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University of Kentucky

Selected Works

2011

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Open Access: Good For Readers, Authors, And Journals, James M. Donovan, Carol A. Watson Nov 2011

Open Access: Good For Readers, Authors, And Journals, James M. Donovan, Carol A. Watson

James M. Donovan

Readers, authors, and even law journal publishers will all achieve their different but related interests by adopting open access principles. Readers of every kind will have more efficient access to the materials they need to pursue their intellectual and informational goals; authors will see their works read and cited by a broader audience; and law reviews and journals can raise their own profiles without injuring their revenue streams from fee-based sources. Open access works for everyone, and is the future of information creation and distribution.


Pre- And Post-Bronchodilator Lung Function As Predictors Of Mortality In The Lung Health Study, David M. Mannino, Enrique Diaz-Guzman, Sonia Buist Oct 2011

Pre- And Post-Bronchodilator Lung Function As Predictors Of Mortality In The Lung Health Study, David M. Mannino, Enrique Diaz-Guzman, Sonia Buist

David M. Mannino

Background

Chronic obstructive pulmonary disease (COPD) is supposed to be classified on the basis of post-bronchodilator lung function. Most longitudinal studies of COPD, though, do not have post-bronchodilator lung function available. We used pre-and post bronchodilator lung function data from the Lung Health Study to determine whether these measures differ in their ability to predict mortality.

Methods

We limited our analysis to subjects who were of black or white race, on whom we had complete data, and who participated at either the 1 year or the 5 year follow-up visit. We classified subjects based on their baseline lung function, according …


Preventive Medicine Introduction, F. Douglas Scutchfield Md Aug 2011

Preventive Medicine Introduction, F. Douglas Scutchfield Md

F. Douglas Scutchfield MD

No abstract provided.


Follow-Up Testing In Functional Anova, Olga A. Vsevolozhskaya, Mark C. Greenwood Aug 2011

Follow-Up Testing In Functional Anova, Olga A. Vsevolozhskaya, Mark C. Greenwood

Olga A. Vsevolozhskaya

Functional analysis of variance involves testing for differences in functional means across k groups in n functional responses. If a significant overall difference in the mean curves is detected, one may want to identify the location of these differences. Two different follow-up testing methods are discussed and contrasted. A point-wise test proposed by Cox and Lee (2008) is compared to a test based on regions of the functional domain. The methods are contrasted in terms of weak control of the family-wise error rate, strong control of the family-wise error rate, and power.


Race-Ethnicity As An Effect Modifier Of The Association Between Hbalc And Mortality In U.S. Adults Without Diagnosed Diabetes, Katharina G. Kehl, Hannes M. Findeisen, David W. Fardo, Dennis Bruemmer, David M. Mannino, Wayne T. Sanderson Aug 2011

Race-Ethnicity As An Effect Modifier Of The Association Between Hbalc And Mortality In U.S. Adults Without Diagnosed Diabetes, Katharina G. Kehl, Hannes M. Findeisen, David W. Fardo, Dennis Bruemmer, David M. Mannino, Wayne T. Sanderson

David M. Mannino

Objective

HbAlc is increasingly appreciated as a risk factor for all-cause and cardiovascular disease (CVD) mortality in the non-diabetic population. In this study, we investigated the association between HbAlc and mortality with a particular focus on the impact of race–ethnicity.

Design

Cohort study.

Methods

We analyzed the association between HbAlc and all-cause and CVD mortality in 12 698 non-diabetic adults 20 years or older from the Third National Health and Nutrition Examination Survey using separate models for people of different race–ethnicity.

Results

In our stratified analyses, higher non-diabetic HbAlc levels were associated with all-cause and CVD mortality in non-Hispanic whites …


Phssr Research Agenda, F. Douglas Scutchfield Md Jun 2011

Phssr Research Agenda, F. Douglas Scutchfield Md

F. Douglas Scutchfield MD

No abstract provided.


Gender Differences In Smoking Behaviour And Cessation, Chizimuzo T.C. Okoli, Iris Torchalla, Natalie Hemsing, Lorraine Greaves Jun 2011

Gender Differences In Smoking Behaviour And Cessation, Chizimuzo T.C. Okoli, Iris Torchalla, Natalie Hemsing, Lorraine Greaves

Chizimuzo T.C. Okoli

This article reviews the literature to compare differential outcomes among men and women after smoking cessation, assess barriers they may face during cessation and provide recommendation to address gender-specific challenges in smoking cessation interventions. There is some evidence that women achieve lower abstinence rates than men after a quit attempt with nicotine replacement therapy, as well as without pharmacotherapy, and several underlying mechanisms were discussed to account for these findings. These include: (a) women have specific genetic variants that affect pharmacokinetics and pharmacodynamics of the medication, (b) hormonal influences increase nicotine metabolism and withdrawal symptoms, (c) women are more responsive …


Smoking Cessation Among Persons With Co-Occurring Substance Use Disorder And Mental Illness, Chizimuzo T.C. Okoli, Milan Khara Jun 2011

Smoking Cessation Among Persons With Co-Occurring Substance Use Disorder And Mental Illness, Chizimuzo T.C. Okoli, Milan Khara

Chizimuzo T.C. Okoli

Aims: A history of either a substance use disorder (SUD) or psychiatric disorder (PD) is associated with tobacco use. However, there is limited information available on tobacco dependence treatment outcomes among individuals with co-occurring SUD and PD. Methods: Data from 202 participants enrolled in a tobacco dependence treatment program in an outpatient clinic setting were analysed. Findings: In multivariate analysis, having a history of SUD only (OR =.11, 95% CI = .02–.76) and having a co-occurring SUD and PD (OR = .13, 95% CI = .02–.81), as compared to having neither, were significant predictors of a lower likelihood of achieving …


Public Health Finance Management Needs And How Public Health Agencies Are Funded., F. Douglas Scutchfield Md May 2011

Public Health Finance Management Needs And How Public Health Agencies Are Funded., F. Douglas Scutchfield Md

F. Douglas Scutchfield MD

No abstract provided.


Men's Smoking Cessation Interventions: A Brief Review, Chizimuzo T.C. Okoli, Iris Torchalla, John L. Oliffe, Joan L. Bottorff May 2011

Men's Smoking Cessation Interventions: A Brief Review, Chizimuzo T.C. Okoli, Iris Torchalla, John L. Oliffe, Joan L. Bottorff

Chizimuzo T.C. Okoli

Background: Smoking is associated with adverse health effects and significant disease burden among men, making it an important men's health issue. Conversely, smoking cessation is associated with significant reductions in smoking-attributable risk. However, few studies have examined men-specific smoking cessation programs. The aim of our study was to conduct a comprehensive review of the literature to identify men-specific smoking cessation programs to make recommendations about future efforts to develop, implement and evaluate men-centered smoking cessation interventions.

Methods: A comprehensive search of the COCHRANE Library, MEDLINE, and PsycINFO and SIGLE databases was performed. Out of 873 studies that we retrieved from …


Challenges And Strategies In Developing Transdisciplinary Research Capacity, Chizimuzo T.C. Okoli May 2011

Challenges And Strategies In Developing Transdisciplinary Research Capacity, Chizimuzo T.C. Okoli

Chizimuzo T.C. Okoli

Definitions of Intradisciplinary, Multidisciplinary, Interdisciplinary, and Transdisciplinary

Challenges in developing Transdisciplinary Capacity

Models of Transdisciplinary Research

Case Example of Transdisciplinary Research Team: The iTAG Team


The Relationship Between Secondhand Tobacco Smoke (Shs) Exposure And Smoking Behaviours: Designing A Program Of Research, Chizimuzo T.C. Okoli Apr 2011

The Relationship Between Secondhand Tobacco Smoke (Shs) Exposure And Smoking Behaviours: Designing A Program Of Research, Chizimuzo T.C. Okoli

Chizimuzo T.C. Okoli

Overview

- Background and Significance

- Study 1: Literature Review Study

- Study 2: SHS Exposure, Nicotine Dependence, and Smoking Cessation

- Study 3: Hair Nicotine as a Measure of SHS Exposure

- Study 4: Effects of Nicotine Exposure from SHS Among Bar and Restaurant Workers

- Study 5: Nicotine Dependence Symptoms among Young Never-Smokers Exposed to SHS

- Study 6: An Examination of the Relationship between Adolescents’ Initial Smoking Experience and their Exposure to Peer and Family Member Smoking

Conclusions and Future Directions


Smoking And Secondhand Tobacco Smoke Exposure: Prevalence, Prevention, Protection, And Treatment, Chizimuzo T.C. Okoli Apr 2011

Smoking And Secondhand Tobacco Smoke Exposure: Prevalence, Prevention, Protection, And Treatment, Chizimuzo T.C. Okoli

Chizimuzo T.C. Okoli

Prevalence and Disease Burden of Smoking

Strategies for Prevention and Protection

Approaches to Tobacco Dependence Treatment

Example of a Smoking Cessation Program


Copd In Never Smokers: Results From The Population-Based Burden Of Obstructive Lung Disease Study, Bernd Lamprecht, Mary Ann Mcburnie, William M. Vollmer, Gunnar Gudmundsson, Tobias Welte, Ewa Nizankowska-Mogilnicka, Michael Studnicka, Eric Bateman, Josep M. Anto, Peter Burney, David M. Mannino, Sonia A. Buist Apr 2011

Copd In Never Smokers: Results From The Population-Based Burden Of Obstructive Lung Disease Study, Bernd Lamprecht, Mary Ann Mcburnie, William M. Vollmer, Gunnar Gudmundsson, Tobias Welte, Ewa Nizankowska-Mogilnicka, Michael Studnicka, Eric Bateman, Josep M. Anto, Peter Burney, David M. Mannino, Sonia A. Buist

David M. Mannino

Background: Never smokers comprise a substantial proportion of patients with COPD. Their characteristics and possible risk factors in this population are not yet well defined.

Methods: We analyzed data from 14 countries that participated in the international, population-based Burden of Obstructive Lung Disease (BOLD) study. Participants were aged ≥ 40 years and completed postbronchodilator spirometry testing plus questionnaires about respiratory symptoms, health status, and exposure to COPD risk factors. A diagnosis of COPD was based on the postbronchodilator FEV1/FVC ratio, according to current GOLD (Global Initiative for Obstructive Lung Disease) guidelines. In addition to this, the lower limit of normal …


Expecting To Quit: A Best-Practices Review Of Smoking Cessation Interventions For Pregnant And Postpartum Girls And Women, Lorraine Greaves, Nancy Poole, Chizimuzo T.C. Okoli, Natalie Hemsing, Annie Qu, Lauren Bialystok, Renée O’Leary Mar 2011

Expecting To Quit: A Best-Practices Review Of Smoking Cessation Interventions For Pregnant And Postpartum Girls And Women, Lorraine Greaves, Nancy Poole, Chizimuzo T.C. Okoli, Natalie Hemsing, Annie Qu, Lauren Bialystok, Renée O’Leary

Chizimuzo T.C. Okoli

This report examines interventions designed to reduce or eliminate smoking during pregnancy. It considers these interventions using a “better practices” methodology designed by Moyer, Cameron, Garcia, and Maule (2002, p. 124) for intervention studies published prior to 2003, and a systematic review methodology from the National Institute for Health and Clinical Excellence (NICE) (2006) in the UK for those studies published after 2003. We contextualize the results of these analyses in the wider literature on women’s health, women-centred care, and women’s tobacco use to better interpret them. These results build on those in the first edition of Expecting to Quit …


Keep Your Friends Close…And Your Critics Closer, Philip Bernard Md, Janice Marks, Tara Crane, Louis Bezold Md, Erich C. Maul Do, Mph Mar 2011

Keep Your Friends Close…And Your Critics Closer, Philip Bernard Md, Janice Marks, Tara Crane, Louis Bezold Md, Erich C. Maul Do, Mph

Erich C. Maul DO MPH

No abstract provided.


A Brief History Of Phssr: The National Coordinating Center. Lessons From History, F. Douglas Scutchfield Md Feb 2011

A Brief History Of Phssr: The National Coordinating Center. Lessons From History, F. Douglas Scutchfield Md

F. Douglas Scutchfield MD

No abstract provided.


The Association Of Adverse Pregnancy Events And Cardiovascular Disease In Women 50 Years Of Age And Older, Sara M. Freibert, David M. Mannino, Heather Bush, Leslie J. Crofford Feb 2011

The Association Of Adverse Pregnancy Events And Cardiovascular Disease In Women 50 Years Of Age And Older, Sara M. Freibert, David M. Mannino, Heather Bush, Leslie J. Crofford

David M. Mannino

Objective: This study investigates the association between a prior history of pregnancy complications and cardiovascular disease (CVD) among Kentucky women aged ≥50 years.

Methods: Data were analyzed from participants (n = 3909) in the Kentucky Women's Health Registry (2006–2008). Primary outcomes were self-reported prevalence of CVD, including angina, heart attack, heart failure, and arrhythmia. Pregnancy complications used as predictors were preterm labor, preeclampsia, gestational diabetes mellitus (GDM), and third trimester bleeding. Logistic regression analyses were conducted to determine associations between prevalence of CVD and pregnancy complications, controlling for age, education, and smoking status.

Results: Overall, 199 (5.1%) women reported angina, …


Sms Reference Service: A New Point Of Need For Libraries, Margie Ruppel, Amy Vecchione Feb 2011

Sms Reference Service: A New Point Of Need For Libraries, Margie Ruppel, Amy Vecchione

Margie Ruppel

Boise State University's text reference service is growing in popularity among students. BSU librarians chose SMS software and started the service during Summer 2010. Join BSU librarians Amy Vecchione and Margie Ruppel for this session to learn what types of questions are asked through SMS, students' opinions of the service, as well as helpful guidelines for starting your own text referencing service.


Trauma, Psychiatric Disorders, Substance Use, And Smoking Among Women, Chizimuzo T.C. Okoli, Nancy Poole, Natalie Hemsing, Karin O'Leary Feb 2011

Trauma, Psychiatric Disorders, Substance Use, And Smoking Among Women, Chizimuzo T.C. Okoli, Nancy Poole, Natalie Hemsing, Karin O'Leary

Chizimuzo T.C. Okoli

Despite decreasing smoking rates among women in the general population, there remain subgroups of women characterized by high nicotine dependence, who remain less able to quit.

One subgroup of women who continue to smoke at rates higher than the general population are those who: have past experiences of trauma, are vulnerable to psychiatric disorders and have substance use problems/addictions.

However, the prevalence of the co-occurrence of trauma, psychiatric disorders, and substance use problems/ addictions, with smoking among women has not previously been synthesized.

The purpose of this study is to conduct a comprehensive review to identify the prevalence of smoking …


Public Health Services And Systems Research: A Common Meeting Ground, F. Douglas Scutchfield Md Jan 2011

Public Health Services And Systems Research: A Common Meeting Ground, F. Douglas Scutchfield Md

F. Douglas Scutchfield MD

No abstract provided.


Index Of Suspicion Case 2: Cough With Green Phlegm In An 8 Year Old; Bronchiectasis, Jillian Miller Md, Erich C. Maul Do Jan 2011

Index Of Suspicion Case 2: Cough With Green Phlegm In An 8 Year Old; Bronchiectasis, Jillian Miller Md, Erich C. Maul Do

Erich C. Maul DO MPH

No abstract provided.


Treatment Outcomes From The Tdc: A Look At Smoking Cessation Among Patients With Co-Occurring Substance Use And Psychiatric Disorders, Chizimuzo T.C. Okoli Jan 2011

Treatment Outcomes From The Tdc: A Look At Smoking Cessation Among Patients With Co-Occurring Substance Use And Psychiatric Disorders, Chizimuzo T.C. Okoli

Chizimuzo T.C. Okoli

Summary of Key Findings

  • Smoking abstinence at end of program:
    • Intent to treat analysis: 32.2% (83/258)
    • Among program completers: 41.3% (83/201)
  • Significant predictors of abstinence:
    • Having an alcohol, heroin (or other opioid) or marijuana use history was a significant predictor of being less likely to quit smoking when compared to having no history of substance use disorder.
    • Having a lower CO level at program enrolment was a significant predictor of being more likely to quit
    • Attending the TDC program for a longer duration was a significant predictor of being more likely to quit.


Social Justice And An Information Democracy With Free And Open Source Software, C. Sean Burns Jan 2011

Social Justice And An Information Democracy With Free And Open Source Software, C. Sean Burns

C. Sean Burns

This paper includes some thoughts on the implications of proprietary software versus free and open source software with regards to social justice, capital, and notions of an information society versus an information democracy. It outlines what free and open source software is and why it is important for social justice, and it offers three cases that highlight two salient themes. This includes a case about preference ordering & decision-making and two cases about knowing and knowledge.


Autoimmune Hemolytic Anemia In A 2 Year Old Child With Pneumococcal Pneumonia, Matthew Bacon Md, Erich C. Maul Do, Joseph Pulliam, John D'Orazio Md Jan 2011

Autoimmune Hemolytic Anemia In A 2 Year Old Child With Pneumococcal Pneumonia, Matthew Bacon Md, Erich C. Maul Do, Joseph Pulliam, John D'Orazio Md

Erich C. Maul DO MPH

No abstract provided.


Citation Advantage Of Open Access Legal Scholarship, James M. Donovan, Carol A. Watson Jan 2011

Citation Advantage Of Open Access Legal Scholarship, James M. Donovan, Carol A. Watson

James M. Donovan

In this study focusing on the impact of open access on legal scholarship, the authors examine open access articles from three journals at the University of Georgia School of Law and confirm that legal scholarship freely available via open access improves an article’s research impact. Open access legal scholarship—which today appears to account for almost half of the output of law faculties—can expect to receive fifty-eight percent more citations than non–open access writings of similar age from the same venue.


Tonic Inhibition Of Chronic Pain By Neuropeptide Y, Brian Solway, Soma C. Bose, Gregory Corder, Renee R. Donahue, Bradley K. Taylor Jan 2011

Tonic Inhibition Of Chronic Pain By Neuropeptide Y, Brian Solway, Soma C. Bose, Gregory Corder, Renee R. Donahue, Bradley K. Taylor

Renee R. Donahue

Dramatically up-regulated in the dorsal horn of the mammalian spinal cord following inflammation or nerve injury, neuropeptide Y (NPY) is poised to regulate the transmission of sensory signals. We found that doxycycline-induced conditional in vivo (Npytet/tet) knockdown of NPY produced rapid, reversible, and repeatable increases in the intensity and duration of tactile and thermal hypersensitivity. Remarkably, when allowed to resolve for several weeks, behavioral hypersensitivity could be dramatically reinstated with NPY knockdown or intrathecal administration of Y1 or Y2 receptor antagonists. In addition, Y2 antagonism increased dorsal horn expression of Fos and phosphorylated form of extracellular signal-related kinase. Taken together, …