Digital Commons Network^™

Role Of Amyloid Precursor Protein In Neuroregeneration On An In Vitro Model In Alzheimer's Patient-Specific Cell Lines, Lina S. Bedoya Martinez

Honors Undergraduate Theses

Alzheimer's disease (AD) leads to neurodegeneration resulting in cognitive and physical impairments. AD is denoted by accumulation of intracellular neurofibrillary tangles, known as tau, and extracellular plaques of the amyloid beta protein (Aβ). Aβ results from the proteolytic cleavage of the amyloid precursor protein (APP) by β- and gamma-secretases in the amyloidogenic pathway. Although, Aβ has been widely studied for neurodegeneration, the role of APP in both, the healthy and diseased conditions, has not yet been entirely understood. The function that APP has in neural stem cell (NSC) proliferation, differentiation, and migration during adult neurogenesis has been previously studied. Additionally, …

Capillary Electrophoresis Buffer Optimization For Plant Tissue Analysis, Rebekah Davis

Honors Undergraduate Theses

Capillary electrophoresis (CE) is an analytical chemistry approach that allows for the efficient separation by charge of diverse classes of compounds for analysis, including secondary metabolites. The goal of this work was to optimize a buffer system for plant tissue analysis using micellar electrokinetic chromatography (MEKC), and by doing so to understand the role of buffer components in the performance of this form of capillary electrophoresis. In this experiment we implemented a factorial design to optimize buffer composition for separating plant tissue and secondary metabolites. The results of this experiment will be used to optimize a universal buffer for MEKC …

Total Salivary Protein Concentration And Its Correlation To Dental Caries, Emyli Peralta

Honors Undergraduate Theses

Introduction: According to the World Health Organization, dental cavities are the number one chronic disease in children. Saliva coats the teeth all day and can serve many functions to maintain and protect teeth. Saliva has many proteins that can be both detrimental and essential to the preservation of tooth enamel. The purpose of this study is to determine if a correlation exists between the total protein concentration in saliva and the prevalence of cavities in the mouth. We hypothesized that there would be a positive correlation with total salivary protein concentration and the prevalence of cavities in the participant. Methods: …

Willingness To Communicate And International Students' Use Of L2, Michelle Verbitskaya

Honors Undergraduate Theses

Willingness to Communicate (WTC) in the second language (L2) is the "readiness to enter into discourse" which is considered to be the direct precursor of students' communication in L2 (MacIntyre et al., 1998). Oral language is thought to precede written language which creates an assumption that ongoing refining of oral skills may impact writing fluency. In respect to WTC model, there have been several versions that describe the construct (MacIntyre et al., 1998; Wen & Clement, 2003; Matsuoka, 2006). This study references self-efficacy, a cognitive variable in Matsuoka's (2006) proposed model, when analyzing writing as a phenomenon in relation to …

An Investigation Of Textile Fibers By Means Of Rgb Analysis Of Birefringence, Olivia F. Feild

Honors Undergraduate Theses

Fiber analysis using birefringence has been around for years but has only recently been looked at more closely under a microscope. Recent scientists have proposed methods to correct issues found with fiber analysis using birefringence, yet there has not be a defined perfect method. This research will focus on correcting previously found issues with works by Michel-Lévy and Sorensen's, as well as other scientists involved and perfecting the analysis of fiber through birefringence. The goal will be to take this research one step further into the analysis of textile fibers by RGB value analysis and birefringence. The RGB values will …

Relationship Between Executive Function And Postural Control, Lara V. Suarez

Honors Undergraduate Theses

While it has been established that postural control is affected by executive function, research is lacking in identifying if specific executive function components are most responsible or if certain aspects of postural control are more affected than others (e.g., proprioception, vestibular, visual). The current study examined the role of inhibition, processing speed, and visuospatial ability in postural control under conditions affecting visual, proprioceptive, and vestibular sensory input. Cognitive assessments consisted of the Flanker Inhibitory Control and Attention Test, Digit Symbol Substitution Test, Clock Drawing Test, Trail Making Test – Part B, and simple reaction time. Standing Balance was used to …

Recruit Quality And College Football Team Performance In The Cfp Era, Jordan Aaron Izenwasser

Honors Undergraduate Theses

Recruiting is a major component of college football. Teams compete for recruits since the quality of a recruiting class contributes to on-field success. Previous studies have investigated the relationship between recruit quality and on-field performance and have found that a positive relationship exists. This thesis contributes to the literature by empirically examining how recruit quality affects team performance in the College Football Playoff (CFP) era using various measures of success. Panel data econometric models are used to determine the effect of recruits between schools, as well as within both conferences and schools on team performance. It also considers the validity …

Timescales Of Global Tidal Flooding, Maria Bower

Honors Undergraduate Theses

Millions of people in low-lying areas are already affected by flooding, and the number will increase substantially in the future. Tidal flooding, the form of flooding caused by a combination of high tides and sea level rise to overcome protection levels, can cause damage and inconveniences such as road closures, overwhelmed drainage systems, and infrastructure deterioration from water damage. Tidal flooding already occurs annually in cities along the U.S. east coast, most notably Miami. However, the time it will take for other regions globally to begin to experience tidal flooding has not yet been assessed. Therefore, there is a limited …

Exploring Galvanic Replacement As A Method To Engineer Peroxidase-Mimics Nanoparticles, Kuryn T. Magloire

Honors Undergraduate Theses

Peroxidase enzymes are of critical importance within the scientific community for their applications in biosensing assays. In a living system, natural peroxidases function as catalysts in the oxidation of peroxide (e.g., H2O2) - a harmful byproduct of aerobic processes and convert them into harmless compounds. Such an ability allows peroxidases to serve as labels in biosensing assays, where they are conjugated to antibodies and accurately produce a detection signal by catalyzing substrates. However, due to intrinsic limitations, namely instability, Peroxidase made of proteins substantially inhibit broader applications.

Alternatively, nanoparticles produced from noble metals have been found to exhibit peroxidase-like abilities …

The Effect Of Family And Social Support On Suicidal Ideation In Jails, Megan L. Small

Honors Undergraduate Theses

Suicidal ideation and associated behaviors are up to four times more common among jail inmates than the general community (Jenkins et al., 2005; Hayes, 1986). Research finds a variety of social, biological, and psychological factors interact to influence suicidal thoughts of incarcerated individuals (Bonner, 1992; Borrill et al., 2005). Particularly, psychological distress such as, depression and feelings of hopelessness, along with loss of social support and decreased feelings of connectedness have been linked to suicidal ideation and behaviors (Moscicki, 1997; Hawton & van Heeringen, 2009). Recently, the Centers for Disease Control and Prevention (2017) has emphasized the importance of connectedness …

Current Perceptions Of Undocumented Immigrants In The United States, Gabriela Lozano

Honors Undergraduate Theses

The intent of this thesis is to examine current perceptions that U.S. Americans have about immigrants coming to the U.S. illegally/ undocumented. There is currently an ongoing debate around immigration in today's political climate. Historically, immigration has always happened in the U.S. and has sparked a vast array of feelings from the U.S. population (Obinna 2018). This study aims to contribute to the existing literature on undocumented immigration to the U.S. and opinion surrounding it. The current study uses the opinion of 177 people to compare current perceptions of undocumented people based on gender, income, and political standing. This study …

Health Literacy And Health Information Seeking Behaviors Of Student At The University Of Central Florida, Abigail Mcwhorter

Honors Undergraduate Theses

Health literacy is the skill needed to acquire, read, understand, and use health related information to make informed healthcare decisions. It is also the skill needed to follow and maintain a treatment plan. Having a high or adequate health literacy level is important because possessing poor health literacy skill can have a negative impact on one's overall health. This research is important because there are few studies available on the health literacy levels of undergraduate college students. The majority of health literacy studies focus on at risk or underserved populations with low education. Previous studies have shown that education is …

Female Militarization And Women's Rights: A Case Study Of The Peshmerga And Ypj, Margaret Morgan

Honors Undergraduate Theses

Since 2012, there has been an increase of media attention on the Kurds, particularly women who are active in the YPJ and Peshmerga. Various publications have equated women's militarization with women's liberation. In an effort to more accurately measure this, the following question must be asked; what is the effect of women's military involvement on women's rights? Women that are active in both nationalist movements and traditional state armies are presented with changing gender roles. Post conflict, there is a struggle for women to transfer their newfound autonomy into political activism. The theory outlines a chain in which women participate …

Time Series Forecasting And Analysis: A Study Of American Clothing Retail Sales Data, Weijun Huang

Honors Undergraduate Theses

This paper serves to address the effect of time on the sales of clothing retail, from 2010 to May 2019. The data was retrieved from the US Census, where N=113 observations were used, which were plotted to observe their trends. Once outliers and transformations were performed, the best model was fit, and diagnostic review occurred. Inspections for seasonality and forecasting was also conducted. The final model came out to be an ARIMA (2,0,1). Slight seasonality was present, but not enough to drastically influence the trends. Our results serve to highlight the economic growth of clothing retail sales for the past …

Utilizing Journaling In The Mathematics Classroom: A Handbook Guide For Teachers, Audrey Nicole Wilson

Honors Undergraduate Theses

A handbook designed for teachers to illustrate how to utilize journaling as an effective teaching practice in the mathematics classroom. This thesis was written to illuminate educators about the powerful research and proper strategies for implementing journaling in mathematics. The handbook provides three lesson plan samples using journaling in the mathematics classroom for grades 3-5, strategies and idea for implementing journaling in mathematics, and tips and activities for mathematical journaling. The goal of this handbook is to give teachers clarity, examples, guidance, and strategies on mathematical journaling.

Do Cognitive Metaphors Moderate The Effectiveness Of Protective Behavioral Strategies?, Skyler M. Hoover

Honors Undergraduate Theses

Past research has shown a positive relationship between alcohol consumption and alcohol related consequences. Protective behavioral strategies (PBS) are able to lower the negative effects of drinking alcohol, however, the protective effects of PBS at times is moderated by situational circumstances or individual differences. This study looks at the cognitive metaphor of being a Head or Heart person and the moderating effects it has on PBS and alcohol consumption and alcohol related consequences. Participants completed the AUDIT-C to measure drinking habits, the PBSS to asses strategy usage, the YAAQC to measure drinking problems and a self-report single item measure for …

Measuring Media Multitasking, Alexandria Trombetta

Honors Undergraduate Theses

This study aimed to document the occurrence of media multitasking activity, as well as to explore a possible typology of which media tasks will be distinguished as primary or secondary in a multitasking situation, which primary tasks are most often combined with a secondary task, and what secondary tasks are most likely to be paired with a given primary task. An original questionnaire was developed to collect data on media tasks commonly paired in multitasking situations as well as the reasons for or perceived benefits of pairing these tasks. This questionnaire was given to participants along with several individual differences …

Effects Of Sme Access To Capital On Country Economic Performance: Understanding The Differences Between The Developed And The Developing World, William B. Reed

Honors Undergraduate Theses

The intent of this thesis is to explore the effects of small-medium enterprises' (SME) access to capital on country economic performance and examine the differences between the developed world and the developing world. Specifically, two main questions are addressed: whether there are significantly higher barriers-to-entry through a lack of access to credit in developing countries as well as whether SMEs access to credit around the world has changed over time.

Using a sample of 46 countries and grouping them two different ways (developed vs developing and free-market vs non-free-market), I find a negative correlation between the SMEs access to capital …

Robotic Automation Of A Cnc Machine, Jace Hovey

Honors Undergraduate Theses

Robotic automation of CNC machines is becoming more popular as robot technology advances and becomes more readily available. While some CNC machines can run autonomously with part catchers, vertical milling centers require an external entity to keep the machine running. Collaborative and Industrial robots are the two main selections for automating a vertical CNC milling machine. We investigate specifically which robot type is most effective for machine tending a Haas VF2 vertical milling center. To do this a cell floor plan, risk assessment, overall equipment effectiveness evaluation, and a total cost analysis are performed to compare robots. With this results …

The Envelope Stress Response In Sedimentation-Resistant Escherichia Coli, Neel K. Shah

Honors Undergraduate Theses

Previous research discovered the existence of sedimentation-resistant mutants of E. coli. Genomic studies revealed that these mutants resisted sedimentation due to independent modifications to genes that influenced the Rcs signal transduction pathway, causing increased secretion of an exopolysaccharide capsule comprised primarily of colanic acid. The Rcs system is responsible for detecting envelope stressors; consequently, ampicillin and osmotic stress were used to perturb the cellular envelope and study the response of the mutants compared to wild-type cells. It was found that the overproduction of colanic acid in the mutants confers some resistance to envelope stress; however, the mutants still behaved …

Overview Of Direct Thrombin Inhibitors For Use In Staphylococcus Aereus Infections, Joseph C. Risler

Honors Undergraduate Theses

The pathogenicity and intractable nature of the microorganism Staphylococcus aureus (SA) has been long documented and highlighted by many health care agencies, with emphasis on its ability to exploit the human coagulation system to deadly effect. Two drugs from a class of inhibitors known as Direct Thrombin Inhibitors (DTI) have been shown to have a substantial effect on the enzyme secreted by SA known as Staphylocoagulase (SC), but up until now the application of this potential treatment has been limited. This paper strives to supply an overview of these clinical studies and propose a novel protocol for testing DTI's on …

Physics-Guided Deep Learning For Power System Sate Estimation, Lei Wang

Electronic Theses and Dissertations

Conventionally, physics-based models are used for power system state estimation, including Weighted Least Square (WLS) or Weighted Absolute Value (WLAV). These models typically consider a single snapshot of the system without capturing temporal correlations of system states. In this thesis, a Physics-Guided Deep Learning (PGDL) method incorporating the physical power system model with the deep learning is proposed to improve the performance of power system state estimation. Specifically, inspired by Autoencoders, deep neural networks (DNNs) are utilized to learn the temporal correlations of power system states. The estimated system states are checked against the physics law by a set of …

Standing Up Comedy: Analyzing Rhetorical Approaches To Identity In Stand-Up Comedy, Christopher Grabert

Electronic Theses and Dissertations

My thesis addresses contemporary conversations about stand-up comedy and the art-form's capacity for facilitating complex rhetorical decision-making. I examine how stand-up comedians have positioned themselves on-stage through choices pertaining revealing personal behaviors, personas, and beliefs in public settings. Ultimately, I argue that the art of stand-up does not require truth-telling on-stage, and that there exists an implicit contract between performers and audiences which details comedians' license to share falsehoods, exaggerations, and embellishments on-stage without the repercussions that accompany these actions in other discourse settings. Finally, I evaluate how comics have handled this rhetorical "license," with some performers delivering easily identifiable …

Latinx Student Success In Higher Education: Genres, Racialization, And Generic-Racial Interactions., Delia Garcia

Electronic Theses and Dissertations

Using a transformative mixed methods approach, I explored the ways in which genres and racial projects are constitutive of each other and contribute to the racialization of Latinx students in higher education and result in disparate outcomes for Latinx students. Latinx research participants revealed the myriad ways in which they are racialized throughout the education system and the numerous ways they encounter whiteness on a daily basis. I focused on two genres in particular: the federally mandated race and ethnicity categories and their intersections with Big Data/Predictive Analytics (BDPA) projects at the university. Rhetorical Genre Studies (RGS) and Racial Formation …

Automated Synthesis Of Unconventional Computing Systems, Amad Ul Hassen

Electronic Theses and Dissertations

Despite decades of advancements, modern computing systems which are based on the von Neumann architecture still carry its shortcomings. Moore's law, which had substantially masked the effects of the inherent memory-processor bottleneck of the von Neumann architecture, has slowed down due to transistor dimensions nearing atomic sizes. On the other hand, modern computational requirements, driven by machine learning, pattern recognition, artificial intelligence, data mining, and IoT, are growing at the fastest pace ever. By their inherent nature, these applications are particularly affected by communication-bottlenecks, because processing them requires a large number of simple operations involving data retrieval and storage. The …

Multi-Scale Modeling Of Viscoelastic Thin-Ply Composites, Milinda Madhusanka Yapa Yapa Hamillage

Electronic Theses and Dissertations

Thin ply composites have been under the microscope of researchers for around two decades since Kawabe introduced the thin ply technology, in the Industrial Technology Center in Fukui, Japan. With the advancement of the technological aspects of manufacturing carbon fiber composites the tow spreading has improved so much as to reduce the thickness of a conventional ply up to even six-fold. Over the years carbon fiber composites have gained interest in space structures for reinforcement purposes in antennas, as structural elements that store strain energy and support the deployment of deployable structures, and in reflector concepts. Now thin-ply composites are …

Dia De Los Muertos 2019 Bookmark, Megan M. Haught

Libraries' Documents

No abstract provided.

Research Roadtrip (Pegasus Palooza 2019) Bookmark, Cynthia Dancel

Libraries' Documents

No abstract provided.

Cosmic Consciousneess And Rawlings's The Soujourner, Ashley Andrews Lear

The Marjorie Kinnan Rawlings Journal of Florida Literature

No abstract provided.

University Of Central Florida Libraries, Annual Report 2018-2019, University Libraries

Libraries' Documents

No abstract provided.