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University Of Central Florida Graduate Catalog, 2025-2026, University Of Central Florida Jan 2026

University Of Central Florida Graduate Catalog, 2025-2026, University Of Central Florida

UCF Catalogs

No abstract provided.


Strength Of Association Between High Blood Pressure And Dementia Mortality In Adults, Ryan J. Wells Jan 2026

Strength Of Association Between High Blood Pressure And Dementia Mortality In Adults, Ryan J. Wells

High Impact Practices Student Showcase Spring 2026

Dementia refers to a number of conditions that lead to a decline in cognitive function, with several overlapping symptoms such as a disruptions in thinking, impairments of social abilities, and memory loss being a key indication, among many other signs. These factors may become more apparent as the aging population is at a significantly higher risk. With that being said, it remains important for dementia and its related conditions to receive the attention they deserve to promote the well-being of those affected.

The objective behind the study was to dive into the potential relationship between high blood pressure (hypertension) and …


Trouble In Paradise: Tracking Tropicalization On Mosquito Lagoon Oyster Reefs, Gabriel T. Silva, Maya Kurian, Katherine Manzelli, Kye Pollard, Johanne Hunt, Avarey Johnson, Kiara Cuevas-Gutierrez, Giavanna Harrington, Giles Cherkaoui, Anya Spara, Tai Powell, Jacob Mclean, Ryan Chin, Kriztian Milanes, Nicholas Groves, Michael Theobald, Justin Moya, Melissa Vance, Logan Chapman, Jordyn Delikat Jan 2026

Trouble In Paradise: Tracking Tropicalization On Mosquito Lagoon Oyster Reefs, Gabriel T. Silva, Maya Kurian, Katherine Manzelli, Kye Pollard, Johanne Hunt, Avarey Johnson, Kiara Cuevas-Gutierrez, Giavanna Harrington, Giles Cherkaoui, Anya Spara, Tai Powell, Jacob Mclean, Ryan Chin, Kriztian Milanes, Nicholas Groves, Michael Theobald, Justin Moya, Melissa Vance, Logan Chapman, Jordyn Delikat

High Impact Practices Student Showcase Spring 2026

Climate change has caused average temperatures across the globe to increase and the frequency of freezing events in temperate climates to decrease, leading to tropical species moving polewards. This process, known as tropicalization, has been documented on the eastern coast of Florida as the tropical red mangrove (Rhizophora mangle) encroaches into temperate communities once defined by the eastern oyster (Crassostrea virginica). Mosquito Lagoon, located within the Indian River Lagoon (IRL) system, is one community that has experienced an increase of 198% in mangrove coverage on intertidal oyster reefs between 1984 and 2017. Although the frequency of freezes has decreased in …


Musculoskeletal Stress Markers Caused By Occupational Stress And Its Relation To Sex, Madison E. Torres, Sage Rohrer Jan 2026

Musculoskeletal Stress Markers Caused By Occupational Stress And Its Relation To Sex, Madison E. Torres, Sage Rohrer

High Impact Practices Student Showcase Spring 2026

The excavation of the site of San Pedro, Belize, uncovered the skeletal human remains of 46 individuals that were naturally preserved well enough in sand to be studied. These remains belonged to ancient Maya, dating back to the Terminal Postclassic to Historic period (c. 1450–1700 CE), who had been buried under what is now the Sands Hotel. This population was part of a small fishing village. These people likely led a labor-intensive lifestyle, which would lead to the skeletal remains showing signs of Musculoskeletal Stress Markers (MSM). This stems from the theory that the males of this village would carry …


The Association Between Sedentary Behavior And Heart Disease Mortality Rates Among Florida Residents., Umed Norkulov Jan 2026

The Association Between Sedentary Behavior And Heart Disease Mortality Rates Among Florida Residents., Umed Norkulov

High Impact Practices Student Showcase Spring 2026

This research project examines the association between sedentary behavior and Coronary Heart Disease (CHD) mortality among Florida residents. As heart disease remains the leading cause of death in Florida, identifying modifiable risk factors is a public health priority. This study utilizes an ecological design to analyze age-adjusted mortality rates across Florida’s 67 counties, correlating them with the prevalence of sedentary lifestyles reported via the Behavioral Risk Factor Surveillance System (BRFSS).

Key findings indicate that sedentary behavior exceeding 10 hours per day is an independent risk factor for heart disease, increasing risk by 8% to 18%, regardless of other physical activity …


Does Dosage Management Of Levothyroxine During Ramadan Improve Outcomes For Hypothyroidism?, John Duran, Dillon Moya, Ethan Cabral, Renan Rodriguez, Mia Ortiz Jan 2026

Does Dosage Management Of Levothyroxine During Ramadan Improve Outcomes For Hypothyroidism?, John Duran, Dillon Moya, Ethan Cabral, Renan Rodriguez, Mia Ortiz

High Impact Practices Student Showcase Spring 2026

Ramadan fasting alters circadian rhythms and meal timing, interfering with the standard dosage of levothyroxine (LT4) on an empty stomach and impact its absorption. The presentation examines whether dosage management of levothyroxine during Ramadan improves the livelihood of patients with hypothyroidism. Hypothyroidism, characterized by deficient production of thyroid hormones (T3 and T4), leads to elevated thyroid-stimulating hormone (TSH) levels due to reduced negative feedback. Since LT4 is used to normalize TSH levels, disruptions in dosing timing during fasting may result in suboptimal thyroid control. A clinical trial was analyzed comparing regular LT4 dosing with an increased dose of 25 mcg …


Early-Life Stress And Skeletal Proportions In Egyptian Juveniles: A Comparative Analysis Of Upper And Lower Limb Growth, Bonnie Radican Jan 2026

Early-Life Stress And Skeletal Proportions In Egyptian Juveniles: A Comparative Analysis Of Upper And Lower Limb Growth, Bonnie Radican

High Impact Practices Student Showcase Spring 2026

Childhood skeletal growth is sensitive to environmental stress, and different limb segments may respond to developmental disruption unequally. This study explained whether lower limb bones showed greater growth deficits than upper limb bones in juvenile skeletal remains from the Kellis 2 cemetery at the Dakhleh Oasis, Egypt, a Roman period site (approximately AD 50-450) where nutritional stress and disease have been previously documented. The delta 1mean method developed by Goode et al., (1993) was applied to six long bones – humerus, radius, ulna, femur, tibia, and fibula – in a combines sample of 98 individuals drawn from original measurements and …


What Truly Drives Graduate Earnings?, Aiden Akbarov Jan 2026

What Truly Drives Graduate Earnings?, Aiden Akbarov

High Impact Practices Student Showcase Spring 2026

The goal of my project, Predicting the Paycheck: What Factors Truly Influence Graduate Earnings?, was to see if we could actually predict a college graduate's starting salary using data instead of just guessing. I used a dataset of 172 majors from the American Community Survey to look at how a student's field of study, the gender balance of their major, and the current job market all impact their first paycheck. I wanted to create a tool that helps students understand the financial reality of their degree before they even graduate.

To get my results, I used a Multiple Linear Regression …


Constrained Dynamics Of Rapid Orbit Motion Emulator (Rome) Using Udwadia-Kalaba Approach, Keanu Brayman Jan 2026

Constrained Dynamics Of Rapid Orbit Motion Emulator (Rome) Using Udwadia-Kalaba Approach, Keanu Brayman

Honors Undergraduate Theses

The Rapid Orbit Motion Emulator (ROME) is designed to be a hardware-in-the-loop (HIL) testbed for orbital control algorithms. It consists of a four-wheeled ground vehicle and a six-degree-of-freedom robotic manipulator. This work investigates the use of optimal control to execute orbital trajectories on ROME using the Udwadia-Kalaba (UK) formulation to model the system dynamics. The UK formulation is a novel method to derive equations of motion for constrained systems. Unlike traditional approaches, the UK approach can be applied directly to any constrained dynamical system. This project utilizes the UK approach to derive dynamics with trajectory following constraints for the ROME …


Non-Invasive Detection Of Intracranial Pressure, Andrei V. Nesterenko Jan 2026

Non-Invasive Detection Of Intracranial Pressure, Andrei V. Nesterenko

Honors Undergraduate Theses

Intracranial pressure is a critical metric used when managing tumors, strokes, TBIs, hydrocephalus, and other operative conditions. Traditional methods for continuous ICP monitoring, intraparenchymal catheters, epidural transducers etc., are invasive and carry a high risk of infection. Previous attempts to create accurate, easy to use, and non-invasive ICP monitoring techniques have been unsuccessful. In this study, we investigated the utility of supraorbital and posterior auricular photoplethysmography to monitor changes in ICP during orthostatic tilt and hyperventilation, which increase and decrease ICP respectively.

Through a continuous 5-minute recording on a tilt-table we characterized SOA and PAA waveforms in 12 participants (ages …


Experimental And Numerical Study On The Stability Limits Of Ammonia And Ammonia/Hydrogen Flames Inside A Toroidal Jet-Stirred Reactor, Guillermo Alberto Barrios Cadenas Jan 2026

Experimental And Numerical Study On The Stability Limits Of Ammonia And Ammonia/Hydrogen Flames Inside A Toroidal Jet-Stirred Reactor, Guillermo Alberto Barrios Cadenas

Graduate Studies Theses and Dissertations 2026

Ammonia’s (NH3) properties as a carbon-free hydrogen carrier, its phase characteristics, and its wide global infrastructure present a solid case as a potential surrogate for carbon-based aviation fuels. Delivering a zero-emission NH3-based engine requires careful integration and optimization of the combustor and thermal management systems, a process that requires high-fidelity chemical reacting models experimentally validated through the use of simplified combustors. This study investigates NH3 fundamental combustion characteristics at conditions relevant to aviation gas turbines using a newly constructed toroidal jet-stirred reactor (TJSR) facility. Lean blow-off (LBO) experiments were carried out for NH3 blends …


Aeroelastic Simulation Of Shape Adaptive Wing, Allan Alfred Kozich Iii Jan 2026

Aeroelastic Simulation Of Shape Adaptive Wing, Allan Alfred Kozich Iii

Honors Undergraduate Theses

Morphing wings provide aerodynamic qualities that normal fixed wings cannot, such as the ability to improve endurance yet maintain maneuverability, overcome strong gusts, vibrations, and shocks, and handle both ideal flight for both high and low speeds. A critical application of the new generation of morphing wings is the ability to overcome and affect the onset flutter, a self-excited oscillatory instability that has led to the destruction of aircrafts. This work investigates aeroelastic behavior and measurement of a meta-material structured "smart" wing and its attempt to delay the effect of flutter. The variable wing tip model is analyzed through finite …


The Vagabond Way: A Qualitative Study Of Intentional Non-Participation In Structured Society, Lorena E. Black Jan 2026

The Vagabond Way: A Qualitative Study Of Intentional Non-Participation In Structured Society, Lorena E. Black

Honors Undergraduate Theses

This study analyzes intentional vagabondage as both a philosophical position and a lived critique of structured society. Using qualitative fieldwork conducted at Fairlawn Family Church in Fort Pierce, Florida—including ten semi-structured interviews, participant observation, and grounded theory analysis—the study examines how individuals who voluntarily disengage from formal systems of housing, labor, and legality construct meaning, identity, and stability beyond institutional boundaries. The analysis identifies three central themes: rhythm, referring to the patterned routines that sustain mobility; reciprocity, which characterizes social exchange and support networks; and refusal, expressed as a deliberate rejection of societal expectations. While many participants describe their paths …


Survey Measures On Perinatal Cannabis Use, Aaditya Balasubramaniyan, Jacquelyn Reiss, Amy Donley Jan 2026

Survey Measures On Perinatal Cannabis Use, Aaditya Balasubramaniyan, Jacquelyn Reiss, Amy Donley

Institute for Social and Behavioral Science (ISBS)

No abstract provided.


The Effects Of Stress-Related Hormones On Excitatory Synapse Formation, Autumn C. Garvey Jan 2026

The Effects Of Stress-Related Hormones On Excitatory Synapse Formation, Autumn C. Garvey

Honors Undergraduate Theses

Stress profoundly influences brain function through neuromodulatory hormones that regulate synaptic plasticity, yet how temporal patterns of hormone exposure shape excitatory synapse formation remains poorly understood. This study investigates how exposure to stress hormones, norepinephrine and cortisol, affects excitatory synapse development. While existing research primarily compares concentration models, real-world stress occurs in variable patterns that may produce distinct neural outcomes. To address this gap, differentiated Neuro2A neuronal cells are exposed to norepinephrine or cortisol under a continuous treatment paradigm designed to model chronic stress conditions. Following treatment, immunofluorescence imaging is utilized to quantify excitatory synapse formation through analysis of presynaptic …


Comparative Analysis Of Serum-Free Culture Conditions On Cell Proliferation And Extracellular Vesicle Production By Adipose-Derived Stem Cells, Ayna Ghulldu Jan 2026

Comparative Analysis Of Serum-Free Culture Conditions On Cell Proliferation And Extracellular Vesicle Production By Adipose-Derived Stem Cells, Ayna Ghulldu

Honors Undergraduate Theses

Adipose-derived stem cells (ADSCs) are promising candidates in regenerative medicine due to their proliferative capacity, self-renewal, and secretion of extracellular vesicles (EVs) that mediate intercellular communication. Serum-free media has been increasingly explored for MSC culture as it eliminates xenogeneic components, improving human therapeutic suitability. However, comparative evaluation of distinct serum-free formulations on ADSC proliferation and EV output simultaneously remains limited. This study compares a serum-containing medium to three proprietary serum-free media prototypes differing in composition, including the presence or absence of extracellular matrix proteins, to inform the optimization of culture conditions for clinical use. Proliferation, EV characteristics, and gene expression …


The Depuration Of Microplastic Pollution In Aquacultured Indian River Lagoon Oysters, Lee Nguyen Jan 2026

The Depuration Of Microplastic Pollution In Aquacultured Indian River Lagoon Oysters, Lee Nguyen

Honors Undergraduate Theses

Plastics are widely used in consumer goods and industrial manufacturing, and their degradation into microplastics (MP, size < 5 mm) has created an emergent environmental pollutant. Plastics readily enter aquatic environments, where they accumulate additional contaminants and bioaccumulate in organisms. While MP contamination in marine ecosystems is well documented, less is known about MP presence in aquacultured shellfish. Depuration, the process of purging contaminants from shellfish, is conducted in sterile seawater without food, which may cause oyster starvation and death. To date, MP depuration has not been examined in the aquacultured eastern oyster (Crassostrea virginica) in published studies. This study had 3 goals: 1) evaluate the effects of algal feed on oyster survival during depuration, 2) determine the effect of algal feed on depuration effectiveness, and 3) investigate the effect of a ten-day depuration on MP concentration in aquacultured C. virginica soft tissue. MP were quantified in oyster tissues, biodeposits, and in industrial algal feed. Tissues were digested using alkaline solutions, manually examined via microscopy, and analyzed using Fourier-Transform Infrared Spectroscopy (FTIR) to investigate MP polymer …


Noninvasive Monitoring Techniques: The Use Of Scat-Sourced Dna And Camera Traps To Monitor Mammalian Carnivore Species At The Ucf Arboretum, Zachary Montealegre Jan 2026

Noninvasive Monitoring Techniques: The Use Of Scat-Sourced Dna And Camera Traps To Monitor Mammalian Carnivore Species At The Ucf Arboretum, Zachary Montealegre

Honors Undergraduate Theses

The 800-acre University of Central Florida Arboretum Natural Lands functions as a conservation area, recreational space, and research site, making it essential to understand the ecological community it supports. Traditional wildlife monitoring methods such as mark-recapture and blood sampling can be effective but may stress animals or disrupt natural behaviors. To minimize these impacts, this study used non-invasive techniques, specifically scat-based DNA analysis and camera trapping, to assess carnivore species' presence. Two ecologically similar sites within the Arboretum were selected. Suspected carnivore scat was collected twice weekly over two months using both structured and opportunistic sampling. DNA was extracted, amplified, …


The State Of Copyright And Ai: 2026 Updates​, Sarah A. Norris Jan 2026

The State Of Copyright And Ai: 2026 Updates​, Sarah A. Norris

Teaching & Learning with AI

No abstract provided.


How Does Economic Policy Uncertainty Affect Individual Contributions To Retirement Accounts?, David I. Becker Jan 2026

How Does Economic Policy Uncertainty Affect Individual Contributions To Retirement Accounts?, David I. Becker

Honors Undergraduate Theses

This study tests whether Economic Policy Uncertainty (EPU) is associated with U.S. retirement contributions and whether responses differ across account types. Using annual contribution data for defined contribution plans and Traditional and Roth IRAs with the Baker, Bloom, and Davis EPU index, I estimate multivariate regressions with standard macroeconomic controls and compare contemporaneous and lagged specifications. EPU is positively associated with 401(k) contributions, negatively associated with Traditional IRA contributions in the contemporaneous model, and not statistically significant for Roth IRAs. These results suggest uncertainty may shift how households save for retirement rather than uniformly reducing retirement saving.


Associations Between Oral Hormonal Contraceptive Use, Digestive And Other Health Symptoms In Young Women, Silviana E. Buzatu Jan 2026

Associations Between Oral Hormonal Contraceptive Use, Digestive And Other Health Symptoms In Young Women, Silviana E. Buzatu

Honors Undergraduate Theses

Oral hormonal contraceptives (OHCs) are widely used among reproductive-age women; however, their gastrointestinal (GI) side effects remain understudied. The present study examined associations between OHC use, GI, physical, and psychological symptom burden in a large sample of undergraduate women. Participants (N = 669) aged 18 to 25 years were recruited from UCF’s SONA system and classified into three groups based on self-reported contraceptive status: no birth control, combined estrogen–progestin OHC, and progestin-only OHC. Participants completed GI questionnaires, as well as physical and mental health symptoms ones.

Multivariate analyses indicated that overall GI symptom profiles did not differ significantly by birth …


Repurposing Cyclin-Dependent Kinase Inhibitors For The Discovery Of Novel Antiplasmodial Compounds, Ritam Bhowmik Jan 2026

Repurposing Cyclin-Dependent Kinase Inhibitors For The Discovery Of Novel Antiplasmodial Compounds, Ritam Bhowmik

Honors Undergraduate Theses

Malaria remains a major global health burden with over 282 million cases annually and rising resistance to artemisinin-based combination therapies. Plasmodium falciparum, the most lethal malaria parasite species in humans, relies on tightly regulated cell cycle progression during replication within red blood cells. Cyclin-dependent kinases (CDKs) are central regulators of eukaryotic cell division and transcription, and several CDK-like enzymes in P. falciparum, including Pfmrk and PfPK6, are essential for parasite growth and structurally distinct from human kinases. This study evaluated whether commercially available human CDK inhibitors (CDKIs) targeting cancer pathways could be repurposed as novel antimalarial compounds. A library of …


Self-Reported Psychological Effects Of Rock Climbing In Adults On The Autism Spectrum, Brennan Gleason Jan 2026

Self-Reported Psychological Effects Of Rock Climbing In Adults On The Autism Spectrum, Brennan Gleason

Honors Undergraduate Theses

Background: Prior research has shown rock climbing to have considerable therapeutic potential through such mechanisms as boosting self-esteem, promoting mindfulness, and creating a supportive social community. (Liu et al., 2022, Osborne et al., 2025). Meanwhile, autistic adults experience mood disorders at a significantly higher rate than the general population; upwards of 54% are diagnosed with a psychiatric condition (Croen et al., 2015). Many of the issues negatively affecting autistic adults align with the benefits of rock climbing, including low self-esteem, inadequate social support, and anxiety.

Objective: This study aimed to find differences in mental health outcomes between autistic adults who …


Health Care Governance And Structural Exclusion In Florida: A Human Rights Analysis Of Access For Latinx Communities, Natalie Medrano Jan 2026

Health Care Governance And Structural Exclusion In Florida: A Human Rights Analysis Of Access For Latinx Communities, Natalie Medrano

Honors Undergraduate Theses

Access to health care in the United States is a complex system shaped by statutory programs and the discretionary powers of state governance. This thesis examines how Florida’s healthcare system structures access through administrative design, with particular attention to its impact on Latinx communities. Although formally race-neutral, Florida’s reliance on Medicaid non-expansion, managed care delivery, and complex eligibility processes produces systemic barriers that limit access for low-income populations. Drawing on the international right-to-health framework articulated in General Comment No. 14 of the International Covenant on Economic, Social and Cultural Rights, alongside Latinx Critical Race Theory (LatCrit), this study analyzes how …


A Systematic Literature Review Of The Possible Negative Impacts Of Overconsumption Of Mass Media And Technology On Elementary-Aged Members Of Generation Z (1997–2012) And Generation Alpha (2013–2024), Ashya Y. Warren Jan 2026

A Systematic Literature Review Of The Possible Negative Impacts Of Overconsumption Of Mass Media And Technology On Elementary-Aged Members Of Generation Z (1997–2012) And Generation Alpha (2013–2024), Ashya Y. Warren

Honors Undergraduate Theses

This thesis explores the possible negative impacts of overconsumption of mass media and technology on the elementary-aged members of Generation Z (1997-2012) and Generation Alpha (2013-2024). This research is aimed at establishing the relationship between excessive and uncontrolled exposure to digital media and cognitive, emotional, social, behavioral, and academic difficulties at a critical period of child growth. The purpose of this systematic literature review can be explained by the author's experience with technology overuse and professional interests as a future teacher, who should be prepared to help promote healthy childhood and development. The systematic literature review was based on peer-reviewed …


Impact Of Lifestyle Factors On Allergic Rhinitis Symptoms And Quality Of Life Among College Students, Lina Saint-Hilaire Jan 2026

Impact Of Lifestyle Factors On Allergic Rhinitis Symptoms And Quality Of Life Among College Students, Lina Saint-Hilaire

Honors Undergraduate Theses

This study aims to examine the influence of certain lifestyle factors on the presentation of allergic rhinitis symptoms and the quality of life of college students. Factors of interest include residential setting, household cleaning habits, age of symptom onset, and exposure to household pets. Additional analysis includes assessment of the impact of allergic rhinitis symptoms on sleep. Using a cross-sectional survey design, student responses were self-reported through a paper survey distributed during tabling days at the University of Central Florida (UCF) main campus. Eligible participants had to be 18 years or older and current UCF graduate and undergraduate students. Survey …


Evaluating The Effectiveness Of Nurse-Led Prenatal Education On Maternal Outcomes And Labor Satisfaction, Alexis Boris Jan 2026

Evaluating The Effectiveness Of Nurse-Led Prenatal Education On Maternal Outcomes And Labor Satisfaction, Alexis Boris

Honors Undergraduate Theses

Prenatal education has been a long-time major component of maternal healthcare, which has been known to impact expectant mothers and their level of preparedness during the labor and birthing process. Nurses have historically been key educators in the maternity field, due to their accessibility, education, and holistic approach in the healthcare system. Despite their recognition as vital educators in this field and the importance of maternal prenatal education, maternal healthcare is still affected by many modern-day factors, such as access to healthcare and education, health disparities, and negative childbirth experiences. This integrative literature review aims to evaluate the overall effectiveness …


Bodies Of Knowledge: The Accuracy Of Medical Anatomical Drawings From The 14th To The 18th Century, Marina G. Mitchell Jan 2026

Bodies Of Knowledge: The Accuracy Of Medical Anatomical Drawings From The 14th To The 18th Century, Marina G. Mitchell

Honors Undergraduate Theses

From the fourteenth to the eighteenth centuries, European anatomical illustration underwent major transformations in response to changing scientific methods, technologies, and visual conventions, reflecting critical transitions in anatomical history. Scientific evolution allowed these images to achieve increasing structural precision and internal detail, though they frequently diverged from anatomical forms as they are understood today. This study examines how anatomical inaccuracies across five centuries emerged not from ignorance, but from deliberate mediation between purpose, observation, pedagogy, artistic convention, and cultural ideology. Through close analysis of works in visual comparison to their modern counterparts, this thesis identifies specific deviations from the twenty-first …


Social Determinants Of Health Affecting Cardiovascular Health Among South Asian Americans, Ann Mary Thomas Jan 2026

Social Determinants Of Health Affecting Cardiovascular Health Among South Asian Americans, Ann Mary Thomas

Honors Undergraduate Theses

Background: South Asian Americans experience disproportionately high rates of cardiovascular disease, yet the social determinants contributing to these disparities remain understudied.

Objective: This systematic review examines the role of social determinants of health (SDOH) in shaping cardiovascular outcomes among South Asian Americans.

Methods: A systematic literature search was conducted across PubMed, MEDLINE, and Web of Science using predefined search terms related to South Asian populations, cardiovascular health, and SDOH. The review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 reporting guidelines, and study screening and management were performed using Covidence. A total …


Distribution And Morphology Of Catecholaminergic Axons And Terminals In Flat-Mounts Of The Whole Left Ventricles Of Rats: Tracing, Digitization And 3d Scaffold, Emily Liu Jan 2026

Distribution And Morphology Of Catecholaminergic Axons And Terminals In Flat-Mounts Of The Whole Left Ventricles Of Rats: Tracing, Digitization And 3d Scaffold, Emily Liu

Honors Undergraduate Theses

Cardiac sympathetic innervation plays a vital role in regulating various heart functions, and its remodeling has been linked to a range of cardiovascular diseases. To understand cardiac sympathetic innervation and remodeling, it is important to elucidate the topographical distribution and morphology of sympathetic axons in the whole left ventricle. However, immunohistochemistry (IHC) on whole heart tissues presents challenges due to their thickness, as conventional methods label only small sections. This disrupts tissue integrity and neural connections. To overcome this, we developed a whole flat-mount technique to process the rat heart (ventricle thickness: 3 mm). We performed cardiac sympathetic nerve imaging …