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Development Of Cerium Oxide Based Polymer Composites With Enhanced Cytocompatability For Biomedical Applications, Roshna Cherugail Jan 2025

Development Of Cerium Oxide Based Polymer Composites With Enhanced Cytocompatability For Biomedical Applications, Roshna Cherugail

Honors Undergraduate Theses

This thesis presents the synthesis and characterization of cerium oxide nanoparticles (CNPs), and silver-doped cerium oxide nanoparticles (AgCNPs) loaded in alginate beads that were designed to be applied in biomedical settings. Cerium oxide was chosen for its antioxidant and anti-inflammatory capabilities, and silver oxide was selected to enhance antimicrobial functionality, both of which are pivotal in expedited wound closure and promoting cellular proliferation. Through the use of an advance electrospray encapsulation apparatus, alginate-based polymer beads were created by incorporating either CNPs or AgCNPs into the matrix. These beads were later characterized using a range of microscopic and FTIR analyses, in …


Sports And Rhetorical Marginalization: A Case Study Of Angel Reese & Caitlin Clark, Diamond R. Williams Jan 2025

Sports And Rhetorical Marginalization: A Case Study Of Angel Reese & Caitlin Clark, Diamond R. Williams

Honors Undergraduate Theses

This thesis explores the manifestation of racism, sexism, and capitalism in the language and rhetoric of sports media through a case study of WNBA players Angel Reese and Caitlin Clark. This study theorizes that sports media has referred to Reese and Clark with damaging language tied to the intersections of their respective identities. This thesis also identifies and analyzes the presence of repeated themes throughout select sports media that mirror relevant theories surrounding stereotypes, biases, and marginalization in sports. Examining and analyzing the subtle nuances at play allows one to understand how language implicitly reinforces harmful narratives and, thus, how …


Exploring The Effects Of Looping On First And Second Grade English Language Learners (Ells) Students' Reading And Science Achievement, Kiera A. Palmer Jan 2025

Exploring The Effects Of Looping On First And Second Grade English Language Learners (Ells) Students' Reading And Science Achievement, Kiera A. Palmer

Honors Undergraduate Theses

The purpose of this study is to compare the reading and science achievement of first grade ELL students who looped with their teacher to second grade with the reading and science achievement of first grade ELL students who had a different teacher in second grade. Looping is an educational practice that allows teachers to stay with their class for two or more years, it was hypothesized that it would have a positive effect on ELL students’ reading and science achievement. Using a comparative methodology, the study tracked the end-of-year scores of the ELL students in their Florida Assessment of Student …


The Deception Of A Metamorphosis, Heidi A. Hernandez Jan 2025

The Deception Of A Metamorphosis, Heidi A. Hernandez

Honors Undergraduate Theses

With the historic fascination of Roman and Greek mythology, it is easy to get caught up in the epic the tales of the ancient era provide. A price must be paid for the powerful figures of these stories to rise to such heights, and the ancient world finds women to be their preferred form of currency.

Behind these deceptive chronicles are the trials of women left behind, abandoned, abused and subjected to cruel sexual abuse and the elements reduced to their physical value serving as nothing more than a pawn. One woman, a nymph, is amidst this trial, Ovid brings …


Analyzing The Rate Of Femicide Of Indigenous Women In Rural Australia, Eliza C. Finnigan Jan 2025

Analyzing The Rate Of Femicide Of Indigenous Women In Rural Australia, Eliza C. Finnigan

Honors Undergraduate Theses

Femicide is an increasingly prevalent issue in Australia, with rates continuing to rise, especially among Indigenous women in rural Australia, who face compounded vulnerabilities. Within literature focusing on femicide, there is a noticeable lack of direct intersection between data on rural area and Indigenous Australians. This study investigates the relationship between rurality, Indigenous status, and femicide rates from 2018 to 2023. Data was compiled from the RED HEART Campaign, focusing on different demographic factors, including Indigenous status, location, victim-offender relationship, and cause of death. Frequencies and rates were calculated using descriptive statistics and data from the Australian Bureau of Statistics …


Post-Incident Debriefings For Pediatric Intensive Care Nurse Burnout A Scoping Review, Sulah Emilie Monize Jan 2025

Post-Incident Debriefings For Pediatric Intensive Care Nurse Burnout A Scoping Review, Sulah Emilie Monize

Honors Undergraduate Theses

Burnout is prevalent among pediatric intensive care unit (PICU) nurses, impacting between 42-77% of them. High emotional burden, physical demand, and cognitive overload contribute to significant PICU nurse burnout prevalence. Burnout is linked to increased job turnover, compromised patient care, and decreased staff mental well-being. Addressing burnout is crucial to ensure patient safety and maintain care quality. Burnout in adult ICU nurses is well documented but less so with PICU nurses, and they face stressors unique to their setting, such as a vulnerable patient population and unique dynamics with families and providers. This scoping review includes 9 articles examining the …


Examining The Association Between Perceived Stigma And Mental Health Help-Seeking Behavior Among Racial/Ethnic Minority Students In Health Professions Education, Camila A. Agurto Jan 2025

Examining The Association Between Perceived Stigma And Mental Health Help-Seeking Behavior Among Racial/Ethnic Minority Students In Health Professions Education, Camila A. Agurto

Honors Undergraduate Theses

Racial and ethnic minority (REM) students in health professions programs in the U.S. have considerable mental health issues. Still, they are less likely to access mental health services when compared to their White peers. The stigma they face, such as —public stigma, self-stigma, or intersectional stigma, may serve as a barrier to help-seeking. Although there is increasing recognition of the barriers to mental health care experienced by these students, there is no systematic understanding of how perceived stigma associated with mental health issues affects mental health help-seeking by REM students enrolled in health professions education. This systematic literature review aims …


Ad Astra Per Aspera: Legal Revision Of Space Laws And Intellectual Property To Cultivate Global Alliance And Innovation, Jaiden E. Haggiag Jan 2025

Ad Astra Per Aspera: Legal Revision Of Space Laws And Intellectual Property To Cultivate Global Alliance And Innovation, Jaiden E. Haggiag

Honors Undergraduate Theses

This thesis explores the inadequate nature of the current legal space regime and points out the gaps in outer space laws, including the following: Jurisdictional Challenges, Frameworks of Liability, and IP (Intellectual Property) Enforcement, utilizing laws such as the Outer Space Treaty (OST), the Liability Convention, the Registration Convention, the Moon Agreement, the Patent Cooperation Treaty (PCT), and TRIPS, along with national laws like the U.S. Commercial Space Launch Competitiveness Act and The Inventions in Outer Space Act (35 U.S.C. § 105.). Through analysis of current scholarly proposals and treaty evolution and synthesize to provide policy options, the goal of …


An Analysis Of The Constitutionality Of Florida's 2024 Hb 3: “Online Protections For Minors,” Comparative To Other State Regulations Of The Internet, Evan J. Siegel Jan 2025

An Analysis Of The Constitutionality Of Florida's 2024 Hb 3: “Online Protections For Minors,” Comparative To Other State Regulations Of The Internet, Evan J. Siegel

Honors Undergraduate Theses

This thesis examines the constitutionality of the Florida House of Representatives’ 2024 priority bill, HB 3: “Online Protections for Minors,” through its ongoing litigation in North Florida. The broad nature of the bill, which is now Florida law, and its burden on accessing constitutionality protected speech and/or expression may not be consistent with the First and Fourteenth Amendments to the United States Constitution. How the law defines and shapes what material may be accessible to people on the Internet, or the means they would need to use to create a social media account, are questions many other courts have begun …


Parents’ Perspectives On Emotional Regulation In Their Children With Autism Spectrum Disorder, Diana Stewart Jan 2025

Parents’ Perspectives On Emotional Regulation In Their Children With Autism Spectrum Disorder, Diana Stewart

Honors Undergraduate Theses

The current study’s main research question was whether emotional dysregulation of children with Autism Spectrum Disorder (ASD) affects parental stress levels. This project examined various negative emotional reactions, such as anger, sadness, worry, anxiety, and tantrums that were present in children with an ASD diagnosis, ages 4 to 13. The research consisted of five psychological assessments with strong psychometric properties. The whole survey was supposed to be filled out by a parent or a caregiver of a child, since children are considered a vulnerable population when it comes to research. The first assessment was the Childhood Autism Spectrum Test (CAST) …


Remedios Varo: Peregrinaciones, Julia Condes Jan 2025

Remedios Varo: Peregrinaciones, Julia Condes

Honors Undergraduate Theses

At the time of her death, the artist Remedios Varo (1908–1963) left behind over 500 works of art, the majority of which were created in her adopted country of Mexico. Known for her meticulously crafted fantastical paintings, Varo underwent exile and displacement due to first the Spanish Civil War, and later World War II, which led her to relocate to Mexico, where she would create prolifically for the remainder of her life. This paper will examine the effect of those experiences on the artist and the work she produced, attesting to Varo’s ability to translate complex emotions regarding the human …


An Examination Of Preservice Teacher Knowledge Of Attention Deficit Hyperactivity Disorder (Adhd) In The Elementary Classroom, Breana K. E. Webb Jan 2025

An Examination Of Preservice Teacher Knowledge Of Attention Deficit Hyperactivity Disorder (Adhd) In The Elementary Classroom, Breana K. E. Webb

Honors Undergraduate Theses

This study examines the knowledge of preservice teachers with attention deficit hyperactivity disorder (ADHD) and how well prepared they might be when supporting students in elementary classrooms. ADHD is a diagnosed neurodevelopmental disorder in children and has been increasingly diagnosed over the past several years. Teachers play a crucial role in providing effective instruction to each and every student in the classroom. Managing classroom instruction with diverse learning capabilities and behaviors requires teachers to understand the characteristics of ADHD, as well as instructional adaptations and behavioral interventions, among preservice teachers. Findings indicate that while most preservice teachers recognize the basic …


Investigating The Role Of Prostasin In Angiogenesis: A Chorioallantoic Membrane Model Approach, Zaima Aline Jan 2025

Investigating The Role Of Prostasin In Angiogenesis: A Chorioallantoic Membrane Model Approach, Zaima Aline

Honors Undergraduate Theses

Prostasin, also known as PRSS8 or CAP1, is a glycosylphosphatidylinositol (GPI)-anchored extracellular serine protease involved in various physiological and pathophysiological processes. Prostasin expression is observed during key phases of trophoblast invasion and placental development, critical steps in embryo implantation in Rhesus monkeys. This suggests a role for prostasin in extracellular matrix remodeling and tissue invasion, both essential for a healthy pregnancy. Moreover, prostasin appears vital for development as studies in mice show that a germline knockout of the gene leads to significant placental defects and eventual embryonic death, highlighting its importance in vascular and structural development within the placenta.

Building …


Examining The Effect Of A High Fat Diet On The Expression Of Adipokines In A Murine Model Of Barrett's Esophagus, Saagar A. Shah Jan 2025

Examining The Effect Of A High Fat Diet On The Expression Of Adipokines In A Murine Model Of Barrett's Esophagus, Saagar A. Shah

Honors Undergraduate Theses

Chronic acid reflux results in injury to the esophagus and the development of Barrett’s Esophagus (BE). BE elevates the lifetime risk for a patient to develop Esophageal Adenocarcinoma (EAC). Clinically, one of the main risk factors for BE and EAC is obesity, which alters the secretion of inflammatory cytokines by adipocytes, also referred to as adipokines. Conflicting reports have been made to the expression of adipokines and their receptors in the progression to esophageal cancer. Utilizing an inflammation-based mouse model for BE, we hypothesize that alterations in the expression of adipokines and their receptors favor an inflammatory environment associated with …


The Impact Of Socioeconomic Status On Substance Use Amongst The Hispanic Maternal Population, Emily C. Olivo Jan 2025

The Impact Of Socioeconomic Status On Substance Use Amongst The Hispanic Maternal Population, Emily C. Olivo

Honors Undergraduate Theses

Aim: To explore and synthesize existing research that focuses on the relationship between socioeconomic status and the use of substances amongst the maternal Hispanic population. By examining research and these factors, interventions can be identified to lower reported substance use rates amongst Hispanic mothers of childbearing ages.

Background: Minorities such as Hispanic women deal with a myriad of struggles, especially during motherhood. Socioeconomic status and substance use can contribute to a large part of the struggles faced by this population. Hispanic and Latina will be used interchangeably throughout this review of literature.

Method: A comprehensive electronic review of 3 databases …


The Association Between Implicit Bias From Healthcare Providers And Postpartum Depression Among Black Women., Chelsea T. Costa Jan 2025

The Association Between Implicit Bias From Healthcare Providers And Postpartum Depression Among Black Women., Chelsea T. Costa

Honors Undergraduate Theses

Postpartum depression is one of the most common issues that women face after birth. Many different factors can contribute to the development of postpartum depression, including perinatal complications, prenatal depression, or social factors. One of the social factors that Black women, specifically, face leading to postpartum depression is discrimination. The purpose of this literature review is to identify research that focuses on whether implicit bias and discrimination by healthcare providers contributes to postpartum depression among Black women. A literature review was conducted using databases including CINHAL Plus Text, CINHAL ULTIMATE, Medline, and APA Psycinfo, with terms that included “healthcare provider* …


Exploring Patient-Provider Communication In Indian American Populations: A Scoping Review, Pranav S. Nadella Jan 2025

Exploring Patient-Provider Communication In Indian American Populations: A Scoping Review, Pranav S. Nadella

Honors Undergraduate Theses

Effective provider-patient communication directly influences patient satisfaction, treatment adherence, and health outcomes, yet the unique experiences of Indian Americans—one of the fastest-growing U.S. populations—remain underexplored in communication research. This scoping review, following Joanna Briggs Institute guidelines, systematically mapped the existing literature on provider-patient communication involving Indian Americans. Eleven studies met inclusion criteria, with data extracted on methods, populations, and seven coded aspects related to communication.

Findings revealed a narrow focus on first-generation immigrants and women, leaving men’s experiences and second-generation voices largely unexamined. Communication was shaped by language discordance, cultural stigma, family involvement, trust dynamics, and health literacy. No studies …


Organization And Activation Of Caffeine Expectancies, Catherine S. Forsyth Jan 2025

Organization And Activation Of Caffeine Expectancies, Catherine S. Forsyth

Honors Undergraduate Theses

Caffeine is the most consumed and widely used psychoactive substance in the world. Whether someone uses caffeine or not, expectations about use can be influential to some degree. Expectancies exist everywhere and are extremely influential in all aspects of life. Regarding drug use, expectancies can affect behavior, outcomes, and one’s experience with the drug. Caffeine is no exception, caffeine expectancies have been seen to play a role in several actions such as the development, maintenance, and reinforcement of caffeine use. This study examined latent use profiles of caffeine and relationships between the profiles and the activation of caffeine expectancies. Multidimensional …


Spirituality In Place: Assessment Of Spirituality, Place Attachment, And Locus Of Control In College, Chloe Armand Jan 2025

Spirituality In Place: Assessment Of Spirituality, Place Attachment, And Locus Of Control In College, Chloe Armand

Honors Undergraduate Theses

The intent of this thesis is to explore how spirituality in place shapes college students’ cognition. While spiritual development is recognized as an important aspect of student affairs, its influence on cognitive factors such as locus of control and place attachment remains underexplored. This study investigates the relationship between spirituality, place attachment, and locus of control, as well as students’ perceptions of spiritual design elements on UCF’s campus. To assess these perceptions, a Quality of Place Questionnaire for Spirituality was developed. This instrument aims to measure humanity, sensuality, and sustainability in the built environment. This research uncovers the connections between …


Addressing Barriers In The Primary Prevention Of Hypertension In Black People, Makalah Pierre Rn Bsn Jan 2025

Addressing Barriers In The Primary Prevention Of Hypertension In Black People, Makalah Pierre Rn Bsn

Honors Undergraduate Theses

Hypertension is a significant health concern among minority groups, and the black population is most at risk (Abrahamowicz et al., 2023). The black population experience higher prevalence rates of hypertension compared to other racial groups and are more likely to experience hypertension-related problems, including cardiovascular disease (CVD) and chronic kidney disease (CKD).  This literature review explores various nursing interventions aimed at preventing hypertension within this population. In this review, the term “black people or persons” is a broad term used to describe both African Americans and people of Afro-Caribbean decent. This includes various backgrounds such as Haitian, Jamaican, or otherwise …


Factors Associated With Fatalism Among Hispanic And Latina Breast Cancer Survivors, Liara Lopez Torralba Jan 2025

Factors Associated With Fatalism Among Hispanic And Latina Breast Cancer Survivors, Liara Lopez Torralba

Honors Undergraduate Theses

As fatalism, a person’s attitude towards their life, increases, there is a significant level of medical mistrust and avoidance, which can delay cancer diagnoses and affect the prognosis of the disease. Literature has shown that many factors, including age, race, acculturation, locus of control, education, and fear can influence fatalism. However, little research has been conducted on whether fatalism differs independently by Hispanic origin and its associated factors among Hispanic breast cancer survivors. This study used data from the Hispanic Breast Cancer Study at the University of Central Florida. The original study recruited 408 women aged ≥ 20 years, diagnosed …


Investigating The Effect Of Artificial Sweeteners On Fitness And Metastasis In Drosophila Melanogaster, Om R. Patel Jan 2025

Investigating The Effect Of Artificial Sweeteners On Fitness And Metastasis In Drosophila Melanogaster, Om R. Patel

Honors Undergraduate Theses

Artificial sweeteners are widely used sugar substitutes, yet their potential effects on health remain poorly understood. For example, more evidence suggests that frequent consumers of sugar substitutes may also be at increased risk of excessive weight gain, metabolic syndrome, and type 2 diabetes, which contradicts the original purpose of artificial sweeteners. This thesis investigates the impact of artificial sweeteners on health using Drosophila melanogaster as a model organism, focusing on three key areas: viability, excretion, and cancer metastasis. Viability assays revealed that flies exposed to artificial sweeteners exhibited a decrease in progeny, with some concentrations increasing progeny but most decreasing …


Post-Translational Modification Of The Low-Density Lipoprotein Receptor By Serine Proteases, Matthew E. Ruiz Jan 2025

Post-Translational Modification Of The Low-Density Lipoprotein Receptor By Serine Proteases, Matthew E. Ruiz

Honors Undergraduate Theses

Hypercholesterolemia is a disease affecting many Americans and adults worldwide and can lead to further complications such as atherosclerosis, stroke, or pulmonary embolisms making it a major risk factor for heart disease. The disease states are caused by chronically elevated levels of VLDLs that get broken down into LDLs. Cells expressing the LDLR can endocytose LDLs from the blood for use intracellularly as cholesterol and prevent plasma cholesterol deposition in the endothelium. Current treatments include leading healthier lifestyles through dieting and exercise, or pharmacological treatments targeting cellular cholesterol production or dietary cholesterol uptake from the GI tract. The SREBPs are …


Physical Activity And Hypertension Outcomes Around Menopause In Adult Women—A Secondary Analysis Of The All Of Us Research Program, Meriam F. Naguib Jan 2025

Physical Activity And Hypertension Outcomes Around Menopause In Adult Women—A Secondary Analysis Of The All Of Us Research Program, Meriam F. Naguib

Honors Undergraduate Theses

Hypertension significantly impacts menopausal women due to a decrease in estrogen levels. That is due to estrogen level changes, causing many metabolic alterations, one of which is increased vascular resistance, leading to hypertension. Advanced treatments are made available to help alleviate the condition; however, lifestyle modifications—especially physical activity—show a critical role in hypertension control. This thesis explored the effect of physical activity as a non-pharmacological, lifestyle intervention on hypertension in women by menopausal status (pre-, peri-, and post-menopausal). This study used a secondary analysis with a retrospective design. Physical activity was defined using the American Heart Association's (AHA) guidelines (i.e., …


Threading The Needle: Chinese American Adoptees And The In-Between, Annalee Johnson Jan 2025

Threading The Needle: Chinese American Adoptees And The In-Between, Annalee Johnson

Honors Undergraduate Theses

Threading the Needle is a short documentary that investigates the relationships between Chinese American adoptees, their families, and their heritage. The film features two primary participants, Mia Nails and Annalee “AJ” Johnson as they reflect on their Asian American identity, experiences with racism, and their struggles with cultural estrangement. The similarities and differences in their perspectives shed light on both the wonderful and the heartbreaking circumstances of adoption. The contemporary value of the film lies in how it challenges popular representations of the Asian American experience: Though in recent years, Asian American media has become more present in popular culture, …


Assessing The Relationship Between Perceived Psychological And Physical Pain In Adults With Orthopedic Pain, Daniel C. Karimi Dehkordi Jan 2025

Assessing The Relationship Between Perceived Psychological And Physical Pain In Adults With Orthopedic Pain, Daniel C. Karimi Dehkordi

Honors Undergraduate Theses

Suicide remains a public health concern in the U.S., particularly among individuals experiencing chronic pain and psychological distress. This cross-sectional study investigated the relationship between perceived physical and psychological pain in 41 adults with chronic orthopedic conditions. The relationship between other risk and protective factors and perceived levels of pain distress was also examined. Results showed a significant positive correlation between psychological distress and physical pain (r(39) = 0.388, p < .05) and psychological distress and depressive/anxiety symptoms (r (39) = 0.477, p < .01). Psychological distress was moderately associated with feelings of hopelessness (r (39) = 0.403, p < .01), however, the relationship between physical pain and hopelessness was weak and nonsignificant (r (39) = -0.06, p = .71). Contrary to expectations, emotional support did not buffer the effects of psychological distress (r (39) = 0.07, p = 0.66). Mediational analysis confirmed that emotional support did not influence the relationship between physical pain and psychological distress (Beta (β) = -0.969, p = 0.572; Sobel Z = 0.5598, p = 0.575). Age was not correlated with psychological distress (r (39) = -0.24, p = 0.13) or mental health symptoms (r (39) = -0.05, p = .77). While there was no significant difference across sex, males reported higher mental health symptomatology and psychological distress scores than female counterparts. These findings underscore the direct impact of physical pain on psychological distress and challenge assumptions about the protective role of social support. The study highlights the need for integrated, multidisciplinary interventions targeting both physical and psychological pain to mitigate suicide risk among individuals with chronic orthopedic conditions. Future research should iii explore alternative support mechanisms and resilience-building strategies to address the complex interplay of pain, distress, and suicidality.


A Systematic Review Of Dietary Trends, Influencing Factors, And Their Impacts On Cardiovascular Health In Turkish Populations, Pelin L. Özoğlu Jan 2025

A Systematic Review Of Dietary Trends, Influencing Factors, And Their Impacts On Cardiovascular Health In Turkish Populations, Pelin L. Özoğlu

Honors Undergraduate Theses

Cardiovascular disease (CVD) is the leading cause of death globally, including in Türkiye. One key factor influencing CVD prevention is dietary patterns, which directly impacts cardiovascular health. Türkiye traditionally follows the Mediterranean diet (MedDiet), which is acclaimed for its cardiovascular benefits. Despite this, Türkiye continues to experience high rates of CVD, with projections indicating that CVD mortality will double for both men and women by 2030. It is crucial to address diet-related factors, including potential nutritional deficiencies, to reduce cardiovascular health risks.

This research aims to analyze the Turkish community's adherence to the Mediterranean diet to understand why CVD prevalence …


The Effects Of School-Based Menstruation Education Programs On Anxiety And Self-Efficacy In Adolescent Girls: A Systematic Review, Hannah C. Hart Jan 2025

The Effects Of School-Based Menstruation Education Programs On Anxiety And Self-Efficacy In Adolescent Girls: A Systematic Review, Hannah C. Hart

Honors Undergraduate Theses

A significant global knowledge gap exists for adolescent girls regarding what constitutes a healthy menstrual cycle, proper menstrual hygiene practices, and the implications of reproductive maturity that is ushered in by menarche. This limited understanding can lead to poor health outcomes and the development of negative sentiments and beliefs surrounding the normal experience of menstruation.

This systematic review aims to comprehensively investigate the current state of research regarding the effects of school-based, formal menstruation education programs on adolescent girls, particularly the effects on anxiety and self-efficacy related to the management of menstruation. Furthermore, this work aims to take a stance …


A Tail Of Two Fishes: Exploring Population Structure In Two Species Of Fishes Across The Galápagos Islands, Hillary Quach Jan 2025

A Tail Of Two Fishes: Exploring Population Structure In Two Species Of Fishes Across The Galápagos Islands, Hillary Quach

Honors Undergraduate Theses

The Galápagos Islands, a UNESCO World Heritage Site and a biodiversity hotspot with high levels of endemism, is home to over 440 species of fishes. Marine conditions across the Archipelago are greatly influenced by ocean currents in the region. The Pacific Equatorial Undercurrent, South Equatorial Current, and the Humboldt Current deliver waters rich in nutrients across the three major regions within the Galápagos (central, north, and west). These conditions create a dynamic environment close to the equator, enabling diverse species to thrive in distinct parts of the Galápagos. Despite the rich biodiversity in the region and diverse oceanographic conditions, there …


Genomic Epidemiology Of Staphylococcus Aureus Sequence-Type 72, Sachitaa Senthilkumar Jan 2025

Genomic Epidemiology Of Staphylococcus Aureus Sequence-Type 72, Sachitaa Senthilkumar

Honors Undergraduate Theses

Staphylococcus aureus (S. aureus, SA) is a gram-positive bacterial colonizer and pathogen commonly carried on the skin and in the anterior nares of humans. SA colonization may lead to a variety of non-invasive (e.g., skin and soft tissue infections, SSTIs) and invasive (e.g., bacteremia and osteomyelitis) infections. The SA population is comprised of multiple lineages that can be delineated through multi-locus sequence typing (MLST), which compares nucleotide sequences within seven housekeeping genes. Strains belonging to an MLST share a common evolutionary history and phenotypic characteristics like antibiotic resistance or virulence. As a result, the epidemiology of lineages can be …