Digital Commons Network^™

Methods For Defending Neural Networks Against Adversarial Attacks, Sharvil Shah

Electronic Theses and Dissertations, 2020-2023

Convolutional Neural Networks (CNNs) have been at the frontier of the revolution within the field of computer vision. Since the advent of AlexNet in 2012, neural networks with CNN architectures have surpassed human-level capabilities for many cognitive tasks. As the neural networks are integrated in many safety critical applications such as autonomous vehicles, it is critical that they are robust and resilient to errors. Unfortunately, it has recently been observed that deep neural network models are susceptible to adversarial perturbations which are imperceptible to human vision. In this thesis, we propose a solution to defend neural networks against white box …

Computational Methods To Analyze Next-Generation Sequencing Data In Genomics And Metagenomics, Saidi Wang

Electronic Theses and Dissertations, 2020-2023

This thesis focuses on two important computational problems in genomics and metagenomics with the public available next-generation sequencing data. One is about gene regulation, for which we explore how distal regulatory elements may interact with the proximal regulatory elements. The other is about metagenomics, in which we study how to reconstruct bacterial strain genomes from shotgun reads. Studying gene regulation, especially distal gene regulation, is important because regulatory elements, including those in distal regulatory regions, orchestrate when, where and how much a gene is activated under every experimental condition. Their dysfunction results in various types of diseases. Moreover, the current …

Exploration Of Warm-Up Protocols On Muscular Fatigue, Sahil Kapadia

Honors Undergraduate Theses

Muscular dystrophy is a genetically linked myopathy with no cure available. The lack of a cure makes early detection and treatment of muscular dystrophy imperative. When reviewing protocols examining muscular fatigue at submaximal isometric contractions, proper warm-up appeared to be absent and could have caused skewed results and conclusions. This study examines the effects of implementing a warm-up protocol before fatiguing trials. In this study, 10 adult subjects conducted fatiguing protocols with the right rectus at submaximal isometric contractions. The warm-up period included a light walk along with contractions at 20% and 33% of maximal voluntary isometric contraction (MVIC) levels. …

Probing The Effect Of Hyperglycemia On Endothelial Force Generation And Transmission, Jovani J. Gutierrez

Honors Undergraduate Theses

This thesis intends to utilize biomechanics to study the endothelial biomechanical response in a static hyperglycemic microenvironment. Hyperglycemia is a diabetic condition with abnormally high levels of glucose in the bloodstream. The effects of hyperglycemia over time lead to vascular complications resulting in patients being more prone to cardiovascular diseases. Current studies have focused on the molecular mechanisms affected by hyperglycemia; however, the mechanical mechanisms by which hyperglycemia causes vascular structural and functional changes are understudied. Therefore, to study the effects of hyperglycemia in the endothelium, Human Umbilical Vein Endothelial Cells (HUVEC) were cultured under three glucose conditions: normal glucose …

Influence Of Growth Parameters On The Synthesis Of Mos2 Films, Victor Okonkwo

Honors Undergraduate Theses

Information processing is crucial in modern society, placing a great emphasis on the performance of optoelectronic devices to match ever increasing processing and memory needs. Within these devices, MoS₂ has demonstrated great potential as transistors due to its enhanced electrostatic control. As increased layer thickness of quality MoS₂ films have been shown to boost the performance of its transistors, growth parameters for the synthesis of ideally uniform and large area multilayered films via chemical vapor deposition were investigated. By increasing the flow pressure in the system and the growth time, increasing levels of thickness and nucleation density was …

An Investigative Design Of Gas Jet Nozzles And Their Flow Field Effect On Spatial Distribution, Adam Phengsomphone

Honors Undergraduate Theses

Within this study, the presented material has the objective of providing insight and design characteristics for gas jet nozzles that experimentalists and researchers should consider when utilizing this experimental method. Firstly, this study introduces the developing history and necessity for gas jet experiments and its well-known drawbacks, eventually leading to recent studies and founded knowledge regarding the nozzle geometry dependence on the flow field. The simulation methodology of this study will be presented where the discretization of the computational domain, selection of the flow physics model, and overall design of the nozzle geometry is explained and justified. The flow field …

An Introduction To The Comparison Of Seismocardiography And Phonocardiography, Anna C. Voyatzoglou

Honors Undergraduate Theses

The intent of this thesis is to lay groundwork for examining the relationship between seismocardiography (SCG) and phonocardiography (PCG). Both are methods of measuring and describing heart mechanical function. SCG is described as chest vibrations while the heart beats, and PCG is described as acoustic chest surface signal believed to represent the heart valves opening or closing. SCG and PCG have both been used separately in clinical and research settings, but there is currently no clear comparison between the two. Therefore, there has been no way at the present to understand how one signal might inform the other. This study …

Design And Development Of Medical Devices For Multifaceted Applications, Madisyn Messmore

Honors Undergraduate Theses

The fields of biotechnology and biomedical sciences are rapidly evolving and involve the constant growth of knowledge. As a consequence, engineering design has to also remain at the cutting edge in order to not inhibit the growth of these fields. This study focuses on engineering design and analysis as it pertains to the field of biotechnology, at every step of the engineering process. More specifically, how the engineering design and analysis approach can assist in solving medical problems relating to bone diseases and biomaterials. The first part of the study focuses on a project to design and manufacture a novel …

How Adolescents In The Child Welfare System Seek Support For Their Sexual Risk Experiences Online, Taylor L. Moraguez

Honors Undergraduate Theses

Youth in the foster care system experience unique and challenging situations online, such as higher risks of inappropriate messaging (e.g., sexting) and unwanted solicitations from strangers. As a vulnerable group of adolescents, foster youth often use online platforms as a resource to express themselves and seek support over their sexual experiences online. This thesis analyzes how foster youth seek support online for their sexual risk experiences, including sexual abuse, sexting, and sexuality. To understand how adolescents (ages 13-17) in the child welfare system seek support for these experiences, we conducted a thematic analysis of 541 individual posts made by 121 …

Complex Quantum Contagion: A Quantum-Like Approach For The Analysis Of Co-Evolutionary Dynamics Of Social Contagion, Ece Mutlu

Electronic Theses and Dissertations, 2020-2023

Modeling the dynamics of social contagion processes has recently attracted a substantial amount of interest from researchers due to its wide applicability in network science, multi-agent systems, information science, and marketing. Unlike in biological spreading, the existence of a reinforcement effect in social contagion necessitates considering the complexity of individuals in the systems. Although many studies acknowledged the heterogeneity of the individuals in their adoption of information (or behavior), there are no studies that take into account the individuals' uncertainty during their decision-making despite its theoretical and experimental evidence in behavioral economics, decision science, cognitive science, or multi-agent systems. This …

Covid-19 And Diabetes, Radhika Desai

Honors Undergraduate Theses

Patients with Type 2 Diabetes (T2D) have been found to have increased mortality and morbidity for COVID-19 and are at higher risk for severe disease once infected with COVID-19. Clearly, there exists a relationship between T2D and COVID-19 that requires more attention. In order to understand the mechanisms by which T2D contributes to more severe COVID-19 disease, attention was turned to extracellular vesicles (EVs). It was speculated that viral RNA components of the COVID-19 virus may have originated from circulating EVs that came from infected cells and use a Trojan Exosome method to infect host cells. It is necessary to …

Computational Strain Analysis In Microbiome Datasets With Application To Skin Disease, Minerva Fatimae Ventolero

Electronic Theses and Dissertations, 2020-2023

Identifying bacterial strains is important not only for human health research but also for various environmental and industrial applications. The plethora of available shotgun metagenomic datasets provide an unprecedented opportunity to discover novel bacterial strains in different environmental niches. In this thesis, we evaluated the existing novel-strain-based tools and showed that their performance is still suboptimal. Due to the difficulty in distinguishing strains of similar abundance by available tools, the SMS (strains in multiple samples) tool was developed to de novo identify bacterial strains in multiple shotgun metagenomic samples. We showed that SMS distinguishes strains of similar abundance well and …

Transcinematheque: Defining Cinematic Language In The Trans New Wave, Mel Turnage

Honors Undergraduate Theses

This thesis aims to analyze the films of the Trans New Wave in order to define tropes and motifs of cinematic language and structure. The language of the filmmaking itself presents a different approach from mainstream transgender films, and this changes how certain imagery of transness is contextualized in a larger narrative. In particular, the films of the Trans New Wave operate in contrast to both historical trans films and modern prestige/studio films to deliver more realistic portrayals of trans peoples’ experiences and beliefs. This new language of the Trans New Wave serves to create a more accurate and profound …

Attachment, Identity Processing Style, And Emotion Regulation Among Emerging Adults, Kaitlyn M. Daleandro

Honors Undergraduate Theses

This study explores the relationships among parent, peer, and romantic attachment, identity processing style, and emotion regulation. Previous studies have revealed potential associations among each of the aforementioned factors (e.g., between identity and attachment as well as between attachment and emotion regulation), but this is the first study to examine the three factors together, putting emphasis on romantic attachment. It was predicted that attachment will vary depending on the interaction between identity processing style and emotion regulation. College students (N= 390) in psychology courses participated in an anonymous online survey for course credit. Parent attachment was significantly predicted …

The Effect Of Anti-Aging Treatment On Expression Of Aging Markers In A Mouse Model Of Huntington Disease, Mary Isabelle E. Guerra

Honors Undergraduate Theses

Huntington disease (HD) is a fatal neurodegenerative disease caused by CAG tract expansion in the huntingtin (HTT) gene, which results in production of mutant huntingtin (mtHTT) protein. Although mtHTT is expressed throughout life, onset of HD symptoms typically begins in mid-life, around 35 to 50 years of age. Characteristic HD symptoms include motor, cognitive, and psychiatric abnormalities. The emergence of symptoms in adulthood suggests that aging may play a role in HD pathogenesis. Furthermore, markers of accelerated aging can be observed in HD patients, including telomere attrition, epigenetic alterations, and mitochondrial dysfunction. Our lab has previously observed that …

Analyzing The Relationship Between The Quality Of Life And Race Of Lung Cancer Survivors, Alina S. Wise

Honors Undergraduate Theses

Purpose: The relationship between racial disparities and the health-related quality of life (HRQoL) of lung cancer patients is not well understood. The purpose of this study was to quantify the overall HRQoL of lung cancer patients and compare differences in HRQoL among racial groups in the United States.

Methods: We analyzed data from the Behavioral Risk Factors Surveillance System (BRFSS), a population-based national cross-sectional study conducted by the Centers for Disease Control and Prevention. The BRFSS is conducted annually in all 50 states and collects information on demographics, health behaviors, health-related experiences, health conditions, use of medications, and use of …

Spies, Sanctions, And Single-Party States: How American Sanctions Influence Intelligence Operations, Anthony J. Anta

Honors Undergraduate Theses

States have a diverse and unique set of available mechanisms to deploy when seeking to interact in the international community. Economic sanctions have long been one such tool available for states looking to coerce or incentivize a change in the behavior of another state. Likewise, states have historically sought to influence and gain unknown knowledge on another state or actor. Covert intelligence operations have changed forms, mechanisms, and techniques, especially since the expansive advancements in technology in the 21^st century. This paper seeks to understand the influence that economic sanctions have on the ability for single-party states to conduct …

Characteristics Of Covid-19 Vaccine-Hesitant Ucf College Students And Potential Avenues For Increasing Vaccination Rates, Justin A. Barthel

Honors Undergraduate Theses

The COVID-19 pandemic has been an ongoing disaster that has devasted millions of lives. With the development of COVID-19 vaccines in late 2020, there was a potential for populations to gain artificial active immunity in order to prevent future outbreaks. However, despite successful clinical trials, millions of citizens have been hesitant to receive the COVID-19 vaccines (Khubchandani et al., 2021). Demographics of the most prominent US vaccine-hesitant populations consist of ethnic/racial minorities and Republicans groups (Khubchandani et al., 2021). Little information is known about COVID-19 vaccine hesitancy in colleges and universities. Colleges provide an elevated risk for infection through their …

A Novel Drug To Induce Apoptosis In Advanced Prostate Cancer Cells, Parshva A. Sanghvi

Honors Undergraduate Theses

Prostate cancer is one of the leading causes of death for men in America as approximately 1 in 41 men will have prostate cancer. In this research, we focus on enzalutamide-resistant prostate cancer cells as cell resistance to enzalutamide is a prevalent obstacle in treating prostate cancer. We tested a novel compound library at different doses and observed each compound's efficacy in inducing apoptosis in enzalutamide-resistant cells. Furthermore, we analyzed the mechanism by which apoptosis was induced in compounds that showed a high efficacy at lower doses. Overall, we found that Darapladib shows promising results in treating cells that have …

Sacrificing Sisters: Nurses' Psychological Trauma From The First World War, 1914-1918, Kayla Campana

Electronic Theses and Dissertations, 2020-2023

This thesis examines psychological war trauma nurses experienced during the First World War. Psychological war trauma, or shell shock, as it was commonly known during the war, has largely been identified as a male affliction. In this thesis, I demonstrate that women too, suffered trauma and we can better understand nurses' trauma by applying some of the same analytical techniques that scholars have previously used to examine male combatant trauma. Moreover, I analyze the ways in which contemporary actors, including medical professionals and the public, imagined female trauma, specifically the way nurses' psychological trauma could be understood and articulated. Additionally, …

Workers, Mothers, And Françaises: The French Communist Party And Women In The Interwar Period (1920 - 1939), Elizabeth Klements

Electronic Theses and Dissertations, 2020-2023

A survey of the first two decades of the French Communist Party's propaganda reveals a wide range of female imagery, from the androgynous, Soviet-style militant of the 1920s to the fashionable, feminine figure of the 1930s. Earlier scholars noting this discrepancy argued that the Party first adopted the Soviet "new woman," based on the Marxist principle of absolute gender equality but rejected it just over a decade later in order to broaden their appeal to the French masses. These studies, however, were restricted by the limited access to the French Communist Party's interwar-era archives. Using recently-digitized Party meeting records, reports, …

To The Moon And Back: The Impact Of Moon Rocks On The Historical Legacy Of Nasa's Apollo Program, Emily Strickland

Electronic Theses and Dissertations, 2020-2023

Most would say that the pinnacle of the Space Race was when the United States landed on the Moon. Besides the countless videos and images, what is the proof that the U.S. was there? Moon rocks are tangible evidence that the U.S. was on the Moon. Once the moon rocks came to Earth, they were studied, distributed, and displayed. The goal of this research is to examine the displays and narratives of the Apollo lunar samples. Understanding where and how the rocks ended up in their earthly homes around the country allows for analysis of the historical and cultural impacts …

"We're Not Just Well Suited, We Are Ethically Obligated!": Reimagining Technical And Professional Communication Pedagogy As Advocacy Against Discriminatory Digital Technologies, Anshare Antoine

Electronic Theses and Dissertations, 2020-2023

This dissertation expands on scholarship that examines efforts at incorporating a social justice framework into pedagogy, specifically, the role of technical and professional communication (TPC) faculty in addressing discriminatory digital technologies within a social-justice-oriented tech ethics pedagogy. I observe that despite the thousands of computer technology students who graduate from their programs every year in the US with the latest training, there seems to be no change to the adverse tech culture that produces discriminatory and racist work environments and digital technologies. The implication is that computer technology programs may not be prioritizing a tech ethics pedagogy that supports addressing …

Improving Urban Resilience And Sustainability Via Multi-Scale Urban Food-Energy-Water-Waste Nexus Analysis, Andrea Valencia Marin

Electronic Theses and Dissertations, 2020-2023

Urban sustainable development requires an in-depth and holistic understanding of the complex Food-Energy-Water-Waste (FEWW) nexus facing population growth, climate change, economic development, and pollution control. Following the United Nations (UN) 17 Sustainable Development Goals (SDGs), goal 11 aims for sustainable cities and communities to be resilient, sustainable, and safe cities to achieve social, economic, and environmental sustainability. Explicitly, SDG target 11.3 concentrates on inclusive and sustainable urbanization for sustainable planning and management. As the UN Food System program aims for inclusive, sustainable, and resilient network, promoting sustainable food systems becomes a necessity to echo social, economic, and environmental sustainability. The …

Synthesis, Characterization, And Modeling Of Thermo-Responsive Hydrogels With Improved Mechanical Strength And Swelling Kinetics, Marilu Ortiz Nieves

Electronic Theses and Dissertations, 2020-2023

Hydrogels have been extensively studied for use in applications such as tissue engineering, drug delivery systems, wound dressing, actuators, valves, and sensors in Micromechanical Systems (MEMS), among others. Thermo-responsive hydrogels in particular pose various advantages such as their capability to respond to an external stimulus and reverse the response when the stimulus is removed and the ability to imbibe a significant amount of solvent and increase their volume by over 1000%. Extensive research has been conducted to tune and improve hydrogel’s rate and degree of swelling and mechanical properties. Previous work showed that when synthetic clay (Laponite) is cross-linked with …

Multiomic Hypotheses Underlying Behavioral Manipulation Of Camponotus Floridanus Ants By Ophiocordyceps Camponoti-Floridani Fungi, Ian Will

Electronic Theses and Dissertations, 2020-2023

Parasitic manipulation of host behavior lies at the intersection of disease, animal behavior, and coevolutionary processes. In many of these interactions, the underpinning biology is brought into sharp focus as they are obligate relationships, under strong selection to bring about specific changes in host behavior that determine if the parasite will transmit or die. However, experimental and molecular techniques to understand these interactions are still developing and identification of the mechanisms of manipulation is a primary goal in the field. As such, we investigated host-parasite interactions between Camponotus floridanus (Florida carpenter ant) and Ophiocordyceps camponoti-floridani (Florida zombie ant fungus) from …

The Effect Of Audiovisual And Written Interactivity On Teacher-Candidates' Application Of Instructional Support Practices For English Learners In An Online Tesol Course, Sophie Cuocci

Electronic Theses and Dissertations, 2020-2023

With the increased number of English learners in the United States, teacher candidates need to be prepared to address their needs in their future classrooms. Teacher preparation programs around the nation are continuously exploring solutions to better develop teacher candidates' skills. Simultaneously, the rise in popularity of online education has pushed universities to identify and integrate technology tools which best promote students' learning. This study, connecting both challenges, aims to identify which type of interactivity promoted by technology, in an undergraduate online teaching English for speakers of other languages (TESOL) course, most benefits pre-service teachers in their ability to apply …

How Small Organic Osmolytes Modulate Actin Filament Assembly Kinetics And Mechanics, Pavlo Kravchuk

Electronic Theses and Dissertations, 2020-2023

Actin filament assembly and mechanics are crucial for muscle contraction, maintenance of cell structure, motility, and division. Actin filament assembly occurs in a crowded intracellular environment consisting of various types of molecules, including small organic molecules known as osmolytes. Ample evidence highlights the protective functions of osmolytes such as trimethylamine-N-oxide (TMAO), including their effects on protein stability and their ability to counteract cellular osmotic stress. Recently, TMAO has been shown to counteract the denaturing effects of urea on actin filament assembly based on bulk fluorescence assays. Yet, how TMAO affects individual actin filament assembly dynamics and mechanics is not well …

Compulsory Conformity In Modern Japanese Culture: An Exploration Of Asexuality In The Works Of Murata Sayaka, Kawakami Mieko, And Kamatani Yuki, Nicholas Colecio

Electronic Theses and Dissertations, 2020-2023

This thesis investigates the representation of asexual individuals in the works of Murata Sayaka, Kawakami Mieko, and Kamatani Yuki, all of whom are contemporary Japanese writers that portray near–suffocating social environments in their depictions of modern-day Japan. Their texts illustrate the augmented demands Japanese society places upon a cross-section of asexual and neurodivergent individuals. Despite the thematic and character–related similarities in their works, I argue that each author presents a unique interpretation of how these asexual individuals interact with—and try to integrate into—wider Japanese society and mainstream culture. Murata's texts demonstrate an unapologetically radical separatism by invoking an idealized queer …

Utilizing Geographic Information Systems To Explore The Mortuary Landscape At Kuelap, Peru, Hannah Haynes

Electronic Theses and Dissertations, 2020-2023

The placement of the dead is important for considering social memory, a source of collective knowledge and experiences that shapes social group identity. Mortuary placement is one form of ritual action that communities undertake to remember the dead. This allows anthropologists to ask questions about how humans engaged socially with each other and the landscape. This thesis utilizes an innovative methodological approach combining geographic information systems (GIS) and stable carbon and nitrogen isotope analysis to investigate mortuary variation and social identity within the Late Intermediate Period site (A.D. 800 – 1535) Kuelap in the northern Peruvian Andes. Spatial, demographic, and …