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University of Central Florida

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Attenuation Of Mycobacterium Tuberculosis By Disruption Of A Mas-Like Gene Or A Chalcone Synthase-Like Gene, Which Causes Deficiency In Dimycocerosyl Phthiocerol Synthesis, Tatiana D. Sirakova, Vinod S. Dubey, Michael H. Cynamon, Pappachan E. Kolattukudy Jan 2003

Attenuation Of Mycobacterium Tuberculosis By Disruption Of A Mas-Like Gene Or A Chalcone Synthase-Like Gene, Which Causes Deficiency In Dimycocerosyl Phthiocerol Synthesis, Tatiana D. Sirakova, Vinod S. Dubey, Michael H. Cynamon, Pappachan E. Kolattukudy

Faculty Bibliography 2000s

Tuberculosis is one of the leading preventable causes of death. Emergence of drug-resistant tuberculosis makes the discovery of new targets for antimyrobacterial drugs critical. The unique mycobacterial cell wall lipids are known to play an important role in pathogenesis, and therefore the genes responsible for their biosynthesis offer potential new targets. To assess the possible role of some of the genes potentially involved in cell wall lipid synthesis, we disrupted a mas-like gene, msl7, and a chalcone synthase-like gene, pks10, with phage-mediated delivery of the disruption construct, in which the target gene was disrupted by replacement of an internal segment …

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The Largest Open Reading Frame (Pks12) In The Mycobacterium Tuberculosis Genome Is Involved In Pathogenesis And Dimycocerosyl Phthiocerol Synthesis, Tatianna D. Sirakova, Vinod S. Dubey, Hwa-Jung Kim, Michael H. Cynamon, Pappachan E. Kolattukudy Jan 2003

The Largest Open Reading Frame (Pks12) In The Mycobacterium Tuberculosis Genome Is Involved In Pathogenesis And Dimycocerosyl Phthiocerol Synthesis, Tatianna D. Sirakova, Vinod S. Dubey, Hwa-Jung Kim, Michael H. Cynamon, Pappachan E. Kolattukudy

Faculty Bibliography 2000s

The cell wall lipids in Mycobacterium tuberculosis are probably involved in pathogenesis. The largest open reading frame in the genome of M. tuberculosis H37Rv, pks12, is unique in that it encodes two sets of domains needed to produce fatty acids. Apks12-disrupted mutant was produced, and disruption was confirmed by both PCR analysis and Southern blotting. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) analysis showed that a 430-kDa protein band present in the wild type was missing in the mutant. Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MS) and liquid chromatography (LC)-MS analysis of tryptic peptides showed that 54 peptides distributed …

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University Of Central Florida Commencement, December 13 & 14, 2002, University Of Central Florida Dec 2002

University Of Central Florida Commencement, December 13 & 14, 2002, University Of Central Florida

Commencement Programs

No abstract provided.

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Sandspur, Vol 109, No 10, December 06, 2002, Rollins College Dec 2002

Sandspur, Vol 109, No 10, December 06, 2002, Rollins College

The Rollins Sandspur

Rollins College student newspaper, written by the students and published at Rollins College. The Sandspur started as a literary journal.

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Central Florida Future, Vol. 35 No. 30, December 2, 2002 Dec 2002

Central Florida Future, Vol. 35 No. 30, December 2, 2002

Central Florida Future

Four-year degree at community college.

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Central Florida Future, Vol. 35 No. 29, November 25, 2002 Nov 2002

Central Florida Future, Vol. 35 No. 29, November 25, 2002

Central Florida Future

Students receive a taste of hunger: Banquet addresses real-world poverty; Hitt's raise pushes him to the top; Higher athletic fee to improve sports teams.

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Central Florida Future, Vol. 35 No. 23, November 4, 2002 Nov 2002

Central Florida Future, Vol. 35 No. 23, November 4, 2002

Central Florida Future

Counties hope to avoid third voting disaster; Students upset with Hitt's lack of answers: Gay rights recycling and financial dictate open forum; LASER nears its final stop.

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Central Florida Future, Vol. 35 No. 16, October 10, 2002 Oct 2002

Central Florida Future, Vol. 35 No. 16, October 10, 2002

Central Florida Future

Students vaccinated to fight bio-terrorism; Foot in mouth: Surfer talks smack shark fights back; Higher standards for student leaders.

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Central Florida Future, Vol. 35 No. 14, October 3, 2002 Oct 2002

Central Florida Future, Vol. 35 No. 14, October 3, 2002

Central Florida Future

Greed Today gone tomorrow?; Promises and pork: UCF researchers defend programs' value practicality; Pond pursuit ends safely.

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The Learning Marketspace, October 1, 2002, Bob Heterick, Carol Twigg Oct 2002

The Learning Marketspace, October 1, 2002, Bob Heterick, Carol Twigg

The Learning MarketSpace (7/99 - 2/03)

No abstract provided.

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Sandspur, Vol 109, No 02, September 27, 2002, Rollins College Sep 2002

Sandspur, Vol 109, No 02, September 27, 2002, Rollins College

The Rollins Sandspur

Rollins College student newspaper, written by the students and published at Rollins College. The Sandspur started as a literary journal.

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Central Florida Future, Vol. 35 No. 11, September 23, 2002 Sep 2002

Central Florida Future, Vol. 35 No. 11, September 23, 2002

Central Florida Future

Claiming turf for free speech; Election blunders on the big screen; Students administrators debate openly.

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Central Florida Future, Vol. 35 No. 6, September 5, 2002 Sep 2002

Central Florida Future, Vol. 35 No. 6, September 5, 2002

Central Florida Future

Declining community begins to thrive; Student government downsizing; $640,000 budget will bring comedians concerts to UCF.

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Central Florida Future, Vol. 35 No. 5, September 3, 2002 Sep 2002

Central Florida Future, Vol. 35 No. 5, September 3, 2002

Central Florida Future

SGA president arrested; Walking under the influence; Overlooked party school?

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Central Florida Future, Vol. 35 No. 4, August 29, 2002 Aug 2002

Central Florida Future, Vol. 35 No. 4, August 29, 2002

Central Florida Future

Reno McBride face off; A friend lost not forgotten.

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Central Florida Future, Vol. 35 No. 2, August 22, 2002 Aug 2002

Central Florida Future, Vol. 35 No. 2, August 22, 2002

Central Florida Future

Voters to decide who runs Florida universities; Reno pushes school spending finds fault with DCF choice; SGA budget increases more than $1 million some clubs still denied funding; Democratic candidate wants to improve public education in Florida.

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University Of Central Florida Commencement, August 3, 2002, University Of Central Florida Aug 2002

University Of Central Florida Commencement, August 3, 2002, University Of Central Florida

Commencement Programs

No abstract provided.

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Central Florida Future, Vol. 34 No. 32, May 8, 2002 May 2002

Central Florida Future, Vol. 34 No. 32, May 8, 2002

Central Florida Future

Environment and conservation issues often lack support; Campus crimes preventable; Orlando Magic owner inspires UCF graduates.

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University Of Central Florida Commencement, May 3 & 4, 2002, University Of Central Florida May 2002

University Of Central Florida Commencement, May 3 & 4, 2002, University Of Central Florida

Commencement Programs

No abstract provided.

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University Of Central Florida Undergraduate Catalog, 2002 - 2003, University Of Central Florida May 2002

University Of Central Florida Undergraduate Catalog, 2002 - 2003, University Of Central Florida

UCF Catalogs

No abstract provided.

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University Of Central Florida Graduate Catalog, 2002 - 2003, University Of Central Florida May 2002

University Of Central Florida Graduate Catalog, 2002 - 2003, University Of Central Florida

UCF Catalogs

No abstract provided.

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Sandspur, Vol 108, No 17, April 26, 2002, Rollins College Apr 2002

Sandspur, Vol 108, No 17, April 26, 2002, Rollins College

The Rollins Sandspur

Rollins College student newspaper, written by the students and published at Rollins College. The Sandspur started as a literary journal.

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Central Florida Future, Vol. 34 No. 31, April 24, 2002 Apr 2002

Central Florida Future, Vol. 34 No. 31, April 24, 2002

Central Florida Future

Credit card theft strikes UCF; Eternal Knights Service remembers deceased students; Less Than Jake rocks Spring Fest.

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Central Florida Future, Vol. 34 No. 29, April 10, 2002 Apr 2002

Central Florida Future, Vol. 34 No. 29, April 10, 2002

Central Florida Future

New sports center planned for 2003; Protecting UCF's wetlands a hot topic at Master plan hearing; Relay for Life an emotional event for all.

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Central Florida Future, Vol. 34 No. 24, February 27, 2002 Feb 2002

Central Florida Future, Vol. 34 No. 24, February 27, 2002

Central Florida Future

Landslide victory for Pena ticket; Knight's Krossing bans kegs parties; Students bid for dates with athletes.

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Central Florida Future, Vol. 34 No. 23, February 20, 2002 Feb 2002

Central Florida Future, Vol. 34 No. 23, February 20, 2002

Central Florida Future

Student housing decision postponed; SGA candidates address issues during forum; UCF features African-American artists, guest speakers, comedians.

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Sandspur, Vol 108, No 13, February 15, 2002, Rollins College Feb 2002

Sandspur, Vol 108, No 13, February 15, 2002, Rollins College

The Rollins Sandspur

Rollins College student newspaper, written by the students and published at Rollins College. The Sandspur started as a literary journal.

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Central Florida Future, Vol. 34 No. 22, February 13, 2002 Feb 2002

Central Florida Future, Vol. 34 No. 22, February 13, 2002

Central Florida Future

Chizik leaves UCF; Campaigns begin for 2002-2003 SGA elections; Leadership Week unites students and community.

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Method And Apparatus For Decoupled Thermo-Photocatalytic Pollution Control, Nazim Muradov, Eric Martin, Ali Raissi Jan 2002

Method And Apparatus For Decoupled Thermo-Photocatalytic Pollution Control, Nazim Muradov, Eric Martin, Ali Raissi

UCF Patents

A new method for design and scale-up of photocatalytic and thermocatalytic processes is disclosed. The method is based on optimizing photoprocess energetics by decoupling of the process energy efficiency from the DRE for target contaminants. The technique is applicable to photo-thermocatalytic reactor design and scale-up. At low irradiance levels, the method is based on the implementation of low pressure drop biopolymeric and synthetic polymeric support for titanium dioxide and other band-gap media. At high irradiance levels, the method utilizes multifunctional metal oxide aerogels and other media within a novel rotating fluidized particle bed reactor.

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University Of Central Florida Libraries, Annual Report 2001-2002, Ucf Libraries Jan 2002

University Of Central Florida Libraries, Annual Report 2001-2002, Ucf Libraries

Libraries' Documents

No abstract provided.

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