Digital Commons Network^™

Unlocking Human-Robot Dynamics In Restaurants: Exploring The Mechanisms Underlying The Impacts Of Service Robots’ Social Cues On Restaurant Customer Behaviors, Yusi Cheng

Graduate Thesis and Dissertation post-2024

The rise of service robots (SRs) is reshaping service delivery, particularly in the dining sector where guiding and delivering robots are increasingly prevalent. However, understanding how customers interact with SRs and respond to their social cues in the dining environment remains unclear and fragmented. This dissertation aims to bridge this gap by comprehensively understanding the social cues of SRs and their influences on customer behaviors. Specifically, the objectives are to (1) understand prominent social cues and customer responses; (2) identify key SR-related social cues; (3) explore customer-SR interaction outcomes; (4) explain why certain social cues elicit particular customer responses; (5) …

Mechanistic Insights Into The Antimicrobial Action Of Fungus-Derived Xanthoquinodins Against Clostridioides Difficile, Erika A. Serravalle

Graduate Thesis and Dissertation post-2024

The bacterial pathogen Clostridioides difficile is the leading cause of antibiotic- and healthcare-associated diarrhea, imposing significant clinical and economic impacts. The emergence of hypervirulent strains, such as PCR ribotype 027 (RT027), has exacerbated disease severity, recurrence rates, antibiotic resistance, and epidemiological spread. Expanding resistance profiles among C. difficile strains continue to limit the effectiveness of current IDSA-SHEA recommended therapies, which are already compromised by high recurrence rates due to antibiotic-induced disruption of the gut microbiota. These challenges highlight the urgent clinical need to identify and characterize antimicrobial compounds targeting alternative pathways in C. difficile physiology. We report the discovery and …

Towards Supporting Undergraduate Students To Become Lifelong Learners: A Multimethod, Multimodal, And Multigranular Analysis Of Motivation And Self-Regulated Learning In Context, Sierra Outerbridge

Graduate Thesis and Dissertation post-2024

This publication-based dissertation includes three manuscripts with distinct statistical methods to investigate self-reported motivation, self-reported self-regulated learning (SRL), and enacted SRL processes in undergraduate student contexts towards understanding how students learn how they learn.

The first manuscript focused on 1248 undergraduate statistics students, utilized self-reported motivation, and interpreted logfile data of time spent within an online textbook through the lens of SRL using hierarchical cluster analysis followed by k-means cluster analysis to identify four distinct motivation clusters. Results from a repeated measures ANOVA suggest that students did not spend time differently within the textbook, whereas there were differences between motivation …

Synthesis And Evaluation Of Chalcones As Treatment For Negative Sense Single Stranded Rna Viruses And Applications As Broad-Spectrum Antivirals, Lorael Kirton

Graduate Thesis and Dissertation post-2024

Chalcones are a class of compounds naturally found in plants and are predicated upon a 1,3-diphenylprop-2-en-1-one scaffold. Chalcones possess many biological activities ranging from anticancer to antiviral activities. This thesis investigates the broad-spectrum antiviral properties of chalcones. Some chalcones have been reported to affect host cell mechanisms such as mammalian target of rapamycin (mTOR) signaling cascade or the cell cycle to reduce viral replication. Previously, a series of chalcones 8 were synthesized and investigated in human cytomegalovirus virus (HCMV) and human immunodeficiency virus (HIV). In this study, ten new chalcones predicated upon the design of 8 were synthesized and a …

Comparative Analysis Of Estimation Techniques On Human Performance In Seek-And-Place Tasking, Adam J. Wehr

Graduate Thesis and Dissertation post-2024

Accurate parameter estimation is fundamental to statistical modeling, shaping the validity of inference, prediction, and decision-making. Although Maximum Likelihood Estimation (MLE) and Bayesian methods are well established theoretically, their performance relative to alternative estimators in small-sample, skewed-data contexts remains less clear. This thesis addresses this gap through a systematic evaluation of estimation techniques applied to human response time data from a controlled seek-and-place jigsaw puzzle task, where distributions are characteristically right-skewed.

A performance-modified lognormal model was developed to capture the relationship between task complexity and response times. Four estimation approaches were investigated: MLE, Method of Moments (MoM), Bayesian estimation under …

Domain-Constrained Clustering: A Two-Stage Framework For Muscle Fiber Type Identification, Fanchao Yi

Graduate Thesis and Dissertation post-2024

This dissertation introduces a novel Two-Stage Clustering Framework for the automated identification of human skeletal muscle fiber types using fluorescence microscopy image intensity data. By integrating two complementary clustering methods, this framework overcomes the subjectivity and labor-intensive nature of traditional manual methods, offering an objective and efficient solution for large-scale muscle physiology research. The initial framework combined Density Peaks Clustering (DPC) with a Gaussian Mixture Model employing a t-distribution (GMM-t). This version was validated by comparing its clustering results with manual counts at the individual subject level. We successfully applied this framework in two published studies \cite{brennan2020,hinkley2023}, demonstrating its practical …

A Unified Thermodynamic Framework For Regime Discovery, Entropy-Aware Optimization, And Emergent Leadership In Flocking Systems, Victor Nkwocha

Graduate Thesis and Dissertation post-2024

This thesis presents a unified framework for modeling, optimizing, and analyzing collective behavior in flocking systems through a thermodynamic and statistical lens. In the first study, we employ entropy-regularized Gaussian Mixture Models (GMM) to identify distinct thermodynamic regimes—ordered, transitional, and disordered—based on the energy and entropy profiles of simulated agent-based flocks. The second study introduces the Organic Adaptive Flocking Algorithm (OAFA), a biologically inspired, entropy-aware extension of the Boids model. OAFA dynamically adjusts rule weights based on local entropy signals and is optimized via a multi-objective NSGAII framework to balance cohesion, separation, energy efficiency, and disorder. Results show that entropy …

Clustering And Classification Methods For Forensic Science Applications, Slun Booppasiri

Graduate Thesis and Dissertation post-2024

Finite mixture models have been widely used to cluster data consisting of homogeneous subpopulations. In forensic palynology, pollen is used as a proxy to link individuals or items to a crime scene. Mixtures of pollen data-including willow and mustard and blank samples-were analyzed using flow cytometry. Willow and mustard clusters tend to have multivariate normal distributions, while a background cluster has multivariate non-normal distribution. We propose a finite mixture model capable of handling the mixtures of pollen in terms of univariate and multivariate distribution. The proposed methods are applied in simulated and mixture of pollen datasets.

Finite mixture models typically …

Robust Multiple Change Point Detection For Streaming Data, Randyll Pandohie

Graduate Thesis and Dissertation post-2024

The growing prevalence of high-frequency, high-dimensional data streams in domains such as finance, cybersecurity, and industrial monitoring has intensified the demand for real-time multiple change point detection methods. These methods are expected to identify distributional shifts as they occur while also determining the number and locations of change points—even in the presence of noise, outliers, and limited labeled data. Traditional batch-based approaches and many existing machine learning models fall short in streaming contexts due to their reliance on static datasets and sensitivity to contamination.

This thesis proposes a unified framework for robust multiple change point detection in streaming environments. The …

Beyond The Bench: Historical Injustices And Future Pathways For Florida’S Family Court, David J. Blum

Honors Undergraduate Theses

This thesis examines systemic inequities in Florida’s family law system, focusing on how legal doctrines, discretionary practices, and enforcement patterns disadvantage unwed and noncustodial fathers. Drawing on statutory analysis, case law, empirical studies, and psychological research, it evaluates several reforms designed to promote fairness while protecting child welfare. These include mandatory paternity testing at birth, a rebuttable presumption of equal custody, stronger enforcement of visitation orders, equitable tax restructuring, and improved training for legal professionals. Current Voluntary Acknowledgment of Paternity (VAP) procedures often create binding obligations without confirming biological parentage, resulting in long-term emotional, legal, and financial consequences. Research shows …

Mitigating And Preparing For Disasters At The Organizational Level: A Global Systematic Literature Review, Abdul-Akeem Sadiq, Ratna B. Dougherty, Rebecca Entress, Bikash Adhikari, Katherine Wilson Mccoy, Emilie Rott, Grace L. Chikoto-Schultz, Shannon Maharajh

Faculty Scholarship and Creative Works

Organizations play significant roles in society by providing goods and services and contributing to the economies of communities, globally. Amid the predicted increase in the frequency and impact of disasters, which will invariably lead to higher disaster costs, there is an urgent need to ameliorate disaster impact on society and organizations. Disaster mitigation and preparedness are strategies for stemming disaster impact and losses within organizations. Cognizant of the importance of disaster mitigation and preparedness, researchers have conducted a myriad of studies on both concepts at the organizational level. To advance knowledge on this topic, this study conducted a comprehensive systematic …

Effects Of Invigorating And Relaxing Music On Heart Rate, Blood Pressure, And Heart Rate Variability, Matthew Joshua Faur

Honors Undergraduate Theses

Heart-rate variability (HRV) has been documented to correlate with several health measures, including autonomic nervous system longevity and athletic performance (Zulfiqar, 2010). While increasing age does not affect heart rate, there is a steady decline in HRV, which is a biological marker of aging and the decline of autonomic nervous system function. Furthermore, men who exercise regularly tend to have increased HRV, suggesting a mitigation of the typical age-dependent loss of HRV (Kristal-Boneh et al., 1995). Previous studies have suggested that music may have a physiological effect (e.g., fluctuating vitals, emotional changes) on cardiovascular parameters. However, little is known about …

Comparative Semiotic Analysis Of Non-Verbal Communication: Apis Mellifera Waggle Dance And Human Kinesic Signaling Systems, Nishtha Tikalal

Honors Undergraduate Theses

There are many parallels between two seemingly disparate forms of non-verbal communication: the waggle dance of Apis mellifera (honeybees) and human kinesic signaling systems. Through a comparative semiotic analysis, this research aims to conduct a comparative semiotic analysis, investigating structural and functional similarities between these communication methods, challenging anthropocentric assumptions about meaning making in the natural world. This research employs a meta-synthesis approach, drawn from a methodological literature review to examine historical representations of bee-human relationships, semiotics of non-verbal communication, and the specific mechanisms of the waggle dance and human kinesics. This methodology involves systematic categorization and analysis of extracted …

Respiratory Cycle Influence On Lumbosacral Muscle Function: A Tensiomyographic Analysis, Anthony Trombetta

Honors Undergraduate Theses

Introduction:

Tensiomyography (TMG) has significant potential in examining muscle functionality while evading the limitations found in other methods muscle analysis. Specifically, the erector spinae and other lumbosacral muscles can be analyzed with little challenge. Such analyses include data on muscle displacement (Dm), delay time (Td), contraction time (Tc), half-relaxation time (Tr), and sustain time (Ts). Of these parameters, the most evaluated and with the highest level of reliability are Dm, Td, and Tc. However, stiffness of the lumbar spine and lumbosacral muscles fluctuates throughout the respiratory cycle. These fluctuations may pose an issue when examining the functionality of muscles. This …

Impact Of Tgf-Β And Twist1 On Motility And Proliferation In Estradiol-Treated Mcf-7 Tamr Cells In-Vitro, Thomas L. Scott Iii

Honors Undergraduate Theses

Breast cancer is a highly malignant cancer and is known to be grouped into three main types: adenocarcinoma, invasive ductal carcinoma (IDC) and ductal carcinoma. Breast cancer commonly arises as adenocarcinoma, located in the milk ducts, and becomes IDC when it spreads into the surrounding tissue from the influence of cytokines and hormones. This study outlines the rate of proliferation and motility of a type of adenocarcinoma, MCF-7-TamR, to become invasive ductal carcinoma when Twist1 is downregulated and exposed to TGF- and estradiol (E2) in-vitro. We hypothesize that the downregulation of Twist1 will reduce cell adhesion and cytoskeleton proteins …

Tools And Trends: An Analysis Of Maya Dental Modification, Channing M. Cook

Honors Undergraduate Theses

The ancient Maya practiced dental modification, intentionally filing, incising, and inlaying stones into the front teeth, potentially to display identity and status. The literature surrounding Maya dental modification tends to overlook mechanical aspects of the process, and many studies approach dental modification through limiting or destructive means. Optical microscopy presents an adaptable, cost-effective option for closer inquiry. Preliminary research suggests the process of dental modification leaves distinct patterns of tool use, depending on style, that can be identified through optical microscopy. The sample selected includes 25 incisors and canines from 14 Classic period Maya individuals from Altun Ha, representing 12 …

Lost Innocence, Mateo Valdivieso

Honors Undergraduate Theses

Human trafficking is defined as involving “force, fraud, or coercion to obtain some type of labor or commercial sex act” (U.S. Department of Homeland Security). It disproportionately affects vulnerable populations, particularly children within the U.S. welfare system. This research aims to analyze the characteristics of this system that produce vulnerabilities in welfare children that heighten their risk of being trafficked. The study focuses on socio-economic, psychological, and environmental vulnerabilities, examining how these factors, combined with increased internet accessibility, exacerbate the risks of trafficking. Using a qualitative approach, the research uses secondary data from peer-reviewed journal articles, government reports, and reputable …

Measuring Achilles Tendon Stiffness And Kinetics In-Vivo, Chloe L. Pinkston

Honors Undergraduate Theses

This study aims to measure the gastrocnemii Achilles subtendon passive stiffness and energy storage during walking. Stiffness was first determined using a noninvasive method that combines ultrasound, motion capture, musculoskeletal modeling, and a force transducer. Eight healthy participants were tested using this method to obtain the passive force-displacement relationship of the Achilles tendon at two different knee angles to calculate stiffness of the gastrocnemii subtendon. A gait analysis session was then performed using ultrasound, motion capture, and an instrumented treadmill at self-selected slow, normal, and fast walking speeds, using stiffness to calculate the subtendon’s force and energy storage. Gastrocnemii Achilles …

Comparative Efficacy Of Hallucinogens In Treating Mood Disorders Through A Meta-Analysis Of Symptom Reduction, Dosage, And Duration, John Marco D.F. Muniz

Honors Undergraduate Theses

Background: Hallucinogens including psilocybin, lysergic acid diethylamide (LSD), ketamine, N,N-dimethyltryptamine (DMT) (as ayahuasca), have re-emerged as potential rapid-acting treatments for mood disorders. We conducted a meta-analysis of placebo-controlled trials evaluating their efficacy in depression and anxiety disorders. Methods: A systematic review identified 12 trials (Total ≈ 670) meeting inclusion criteria (randomized, placebo-controlled). Data on Cohen’s d and Hedges’ g effect sizes for depression- and anxiety-related outcomes were extracted. We computed pooled effect sizes (weighted by sample size and inverse variance), performed subgroup analyses by drug, diagnosis, follow-up duration, and outcome measure type, and assessed heterogeneity (I², Q …

Effect Of Metal Ions On The Reactive Oxygen Species Scavenging Capabilities Of Cerium Oxide For Biological Applications, Agastya Mittal

Honors Undergraduate Theses

Ceria nanoparticles' capabilities to defend cells against oxidative stress through superoxide dismutase activity are well-documented. Ceria nanoparticles demonstrate a ratio between 3⁺/4⁺ oxidative states on the surface of the particles to exhibit oxygen vacancies, a feature that allows these particles to scavenge Reactive Oxygen Species (ROS) in times of Oxidative Stress. Oxidative stress arises from many wounds in the body, such as wounds in the skin, and can have significant impacts on the health of an individual. Even when receiving treatment for the skin wound, ROS can circulate from around the wound, be generated from an imbalance …

Optimization Of L-Citrulline Production In Corynebacterium Glutamicum, And The Effect Of The Human Small Intestine Environment, Simran S. Ghulldu

Honors Undergraduate Theses

L-citrulline is a crucial amino acid involved in nitric oxide production, which supports cardiovascular health, physical performance, and intestinal well-being. Nitric oxide deficiency is linked to conditions like hypertension, highlighting the need for efficient L-citrulline production. This study attempts to enhance L-citrulline synthesis in Corynebacterium glutamicum, a bacterium widely used in industrial amino acid production, as well as test a The hypothesis is that overexpressing carAB, which encodes carbamoyl phosphate synthetase, will increase carbamoyl phosphate levels and boost L-citrulline production. Two C. glutamicum strains were used: a wild type and the CRBG strain, which has mutations that promote …

Synthesis And Characterization Of Multifunctional Cerium Oxide Containing Nanoparticles For Biomedical Applications, Ishaan Patel

Honors Undergraduate Theses

This study presents the synthesis and comprehensive characterization of a novel core-shell nanoparticle composed of a maghemite (γ-Fe₂O₃) core and a europium-doped cerium oxide (EuCNP) shell, developed for potential use in cancer theranostics. Using a co-precipitation method, Fe₂O₃–EuCNP core-shell nanoparticles were synthesized and compared against control samples of CNPs, EuCNPs, and Fe₂O₃. A variety of characterization techniques, including UV-Vis spectroscopy, fluorescence spectroscopy, TEM, XRD, XPS, DLS, TGA, and DSC confirmed the successful synthesis of core-shell architecture and europium doping. Moreover, Fe₂O₃–EuCNPs demonstrating strong colloidal …

Investigating The Role Of Prostasin In Angiogenesis: A Chorioallantoic Membrane Model Approach, Zaima Aline

Honors Undergraduate Theses

Prostasin, also known as PRSS8 or CAP1, is a glycosylphosphatidylinositol (GPI)-anchored extracellular serine protease involved in various physiological and pathophysiological processes. Prostasin expression is observed during key phases of trophoblast invasion and placental development, critical steps in embryo implantation in Rhesus monkeys. This suggests a role for prostasin in extracellular matrix remodeling and tissue invasion, both essential for a healthy pregnancy. Moreover, prostasin appears vital for development as studies in mice show that a germline knockout of the gene leads to significant placental defects and eventual embryonic death, highlighting its importance in vascular and structural development within the placenta.

Building …

Examining The Effect Of A High Fat Diet On The Expression Of Adipokines In A Murine Model Of Barrett's Esophagus, Saagar A. Shah

Honors Undergraduate Theses

Chronic acid reflux results in injury to the esophagus and the development of Barrett’s Esophagus (BE). BE elevates the lifetime risk for a patient to develop Esophageal Adenocarcinoma (EAC). Clinically, one of the main risk factors for BE and EAC is obesity, which alters the secretion of inflammatory cytokines by adipocytes, also referred to as adipokines. Conflicting reports have been made to the expression of adipokines and their receptors in the progression to esophageal cancer. Utilizing an inflammation-based mouse model for BE, we hypothesize that alterations in the expression of adipokines and their receptors favor an inflammatory environment associated with …

Unravelling The Role Of Two-Component Systems In Mycobacterium Abscessus, Andrea C. Molero Perez

Honors Undergraduate Theses

Mycobacterium abscessus (Mab) is an emerging pathogen within the nontuberculous bacteria (NTM) which poses a threat due to its complex multi-drug resistance and opportunistic nature. It is predicted that only 45.6% of patients will have successful treatment, with immunocompromised and cystic fibrosis patients being the most threatened. Moreover, investigating new treatment approaches is key to responding to this public health issue. Two-component systems (TCS) are regulatory pathways that play a pivotal role in bacterial survival and virulence. These systems are composed of a sensor histidine kinase (HK) and cognate response regulator (RR) protein that senses environmental cues and triggers specific …

Utilizing Pneumatic Artificial Muscles To Simulate Wingbeat Kinematics For Morphing Uav Wings, Vireli S. Anbarasu

Honors Undergraduate Theses

The controlling muscles of a bird wing change stiffness and length to provide high efficiency when executing a flight maneuver. This variable stiffness allows the muscles to cycle between increasing energy, transmitting it, and restoring it, allowing an overall increase in mechanical and aerodynamic efficiency. Inspired by this, we have developed a system that uses pneumatic artificial muscles (PAMs) to actuate a morphing wing. The stiffness in the PAMS can be controlled to mimic the changes bird flight muscles undergo when executing a forward flapping maneuver. We will evaluate the performance of the PAMs in actuating a morphing wing through …

The Relationship Between Autistic Features And Identity Development Processes Among College Students Through An Intersectional Lens, Alejandra Santana

Honors Undergraduate Theses

Research on autistic features and identity development has indicated that autistic traits are positively associated with identity disturbance (Ratner & Berman, 2015). Characteristic attributes of autism, including circumscribed interests and impairments in social relatedness, align with self-rumination and hardships engaging in the components of identity formation (Gotham et al., 2014). Nonetheless, research on this topic remains scarce. The present study analyzed the association between autistic features and identity formation processes while considering sociocultural factors, such as gender conformity and social camouflaging. A sample of college students enrolled in a large metropolitan city (N = 427) was recruited to complete …

The Role Of Social Media And Acculturation In Body Comparison, Body Dissatisfaction, And Eating Pathology Among Hispanic And Latinx Individuals, Mariana Ortega

Honors Undergraduate Theses

Eating disorders are a group of mental health conditions that are characterized by complex etiologies. The development of eating disorders varies across each individual and their personal background. The current study examined the relationship between levels of acculturation and daily social media use on the presence of body comparison, body dissatisfaction, and eating pathology in Hispanic and Latinx individuals. The aim of this study is to investigate how these factors may lead to a unique etiology of disordered eating, specific to this ethnic group. The current study consisted of two phases. The first phase determined participant eligibility by confirming ethnic …

Healing Through Art: An Exploration Of Art History Influences On Contemporary Art Therapy For Practices In Oncology Care, Nicole Van

Honors Undergraduate Theses

Art therapy has emerged as a vital practice in oncology, offering patients a means of emotional expression and healing during their treatment journey. This project will explore how integrating art history into therapeutic settings, particularly through virtual classes, enhances the emotional well-being of cancer patients. By examining the impact of engaging with historical artworks, this research aims to illustrate how these artistic narratives can facilitate self-consciousness and foster flexibility in individuals facing significant health challenges. Research indicates that exposure to art can evoke emotion and promote psychological healing, serving as a therapeutic outlet for patients. This study will synthesize therapeutic …

Evaluating Coffee And Caffeine Intake In Adults With Cardiovascular Disease: A Comparative Literature Review, Adam Harrington

Honors Undergraduate Theses

Coffee is among the most commonly consumed beverages worldwide, and its bioactive components, including caffeine, affect the cardiovascular system through multiple physiological mechanisms. Patients with cardiovascular disease are typically advised to limit coffee and caffeine consumption because of potential cardiovascular harm, but emerging research challenges this recommendation. This review evaluates recent evidence regarding consumption of whole coffee, caffeine, or decaffeinated coffee in adults with established cardiovascular disease. Database searches conducted across three platforms for studies published after December 2021 yielded 360 records. Following screening against inclusion criteria, 11 studies were reviewed included in the final review. The studies showed variable …