Digital Commons Network^™

Examining The Effects Of Artemisia Annua On Neuro2a Cells, Wesley Lim

Honors Undergraduate Theses

Artemisia annua L. is a well-known medicinal herb used in Traditional Chinese Medicine for many centuries and contains artemisinin, which exhibits antimalarial properties [1] and is a potential treatment for SARS-CoV-2 [2]. However, the neurological effect of A. annua and its compounds are poorly understood. We hypothesize that A. annua extracts and artemisinin will provide protection against oxidative stress in mouse neuronal Neuro2A cells. Superoxide dismutase 1 (SOD1) is an anti-oxidant enzyme that protects against oxidative damage [3]. Growth Arrest and DNA Damage-inducible 45 alpha (Gadd45a) is involved in DNA repair and is a common biomarker for DNA damage[4]. SOD1 …

Curanderismo And Healing: Insights From Hispanic Young Adults, Allisa Castro

Honors Undergraduate Theses

Curanderismo is a holistic form of traditional medicine primarily used by Latin American populations and Hispanic communities in the United States. This type of care focuses on several aspects of health including physical, emotional and spiritual (supernatural). Hispanics are the largest ethnic minority population in the United States and yet healthcare access to this population remains limited by various barriers including lack of insurance, legal status, language, poverty, and other structural factors. Within this context, exploring the perceptions and role of traditional medicine, like curanderismo, as a form of healthcare becomes crucial in understanding and addressing the unique healthcare needs …

Assessing Preventive Care Utilization For Cardiovascular Disease Among U.S. Latinos, Melanie Helena Paredes

Honors Undergraduate Theses

Accounting for nearly 19% of the United States population in 2020, Latinos and Hispanics represent the second largest racial/ethnic group in the United States, totaling roughly 62.1 million people. Given the growing population size and longer life expectancy estimates amongst the U.S. Latino/Hispanic community, healthcare practitioners and public health officials are increasingly emphasizing the healthcare needs and outcomes of this population. Alarmingly, current literature has highlighted significant disparities in cardiovascular disease (CVD) incidence and risk factors among U.S. Latinos/Hispanics. As CVD continues to be one of the leading causes of death amongst all racial/ethnic groups across the United States, risk …

Functional Verification Of Additively Manufactured Metallopolymer Structures For Structural Electronics Design, Nathan D. Singhal

Honors Undergraduate Theses

As an attempt to improve the overall cost-effectiveness and ease of structural electronics manufacturing, this study characterizes the mechanical and electrical responses of structures which are fabricated from a novel metallopolymer composite material by fused deposition modeling as they are subjected to quasi-static, uniaxial mechanical tension. Baseline values of tensile properties and electrical resistivity were first obtained via ASTM D638-22 standard testing procedures and linear sweep voltammetry (LSV), respectively. A hybrid procedure to measure in-situ mechanically dependent electrical behavior was subsequently developed and implemented. The mechanical and electromechanical testing was followed by the derivation of stochastic values for several mechanical …

Exploring The Link Between Neurocognitive Function And Long Covid: A Comprehensive Review, Dinamaris Aguilar

Honors Undergraduate Theses

The intent of this thesis is to provide an in-depth overview of the neurological manifestations associated with long COVID. The review aimed to assess the cognitive functioning symptoms associated with SARS-CoV-2 post-infection (PASC), investigate the potential mechanisms by which SARS-CoV-2 affects the nervous system, contributing to cognitive fatigue, brain fog, and cognitive dysfunction, and explore the parallels between SARS-CoV-2 and Alzheimer’s Disease. Neuroinflammation emerges as a shared element among these mechanisms, significantly impacting cognitive function. The parallels between COVID-19 and Alzheimer's Disease offer insights into how Alzheimer's affects cognition, aiding in understanding COVID-19's impact. The review underscores a notable gender …

The Battle Over Diversity, Equity, And Inclusion And Critical Race Theory In Florida: A Case Study On The Stop W.O.K.E. Act, Grace Anne Castelin

Honors Undergraduate Theses

Accelerating from 2022 and continuing through 2024, the state of Florida has experienced significant policy changes, particularly within the realm of higher education and affairs of diversity, equity, and inclusion (DEI). Many progressive officials, experts, and activists assert arguments that the state is on the verge of evolving into an authoritarian regime while many illiberal policies are being produced through the Florida legislature and current executive leadership—social and economic sectors are consequently threatened in order to maintain political oppression. The Stop W.O.K.E. Act has served as a catalyst for shifting the state's political stance on DEI, culminating in a chain …

The Effects Of Nanobubbles For Gene Delivery For Osteoporosis Treatment, Abel Córdova Flores

Honors Undergraduate Theses

In recent years, the field of nanomedicine has provided promising alternatives to traditional ways of gene and drug delivery, such as nanobubbles instead of viral vectors. Manufacturing these nanomaterials is cost-effective and tends to be safer than previous forms of treatment for clinical use. In the realm of osteoporosis, a disease based around a higher rate of bone resorption to bone formation, leads to weak and brittle bones, leaving sufferers at risk for fractures, which are sudden and unexpected. These fractures are estimated to cost USD 22 Billion annually in the US alone. Reports show a significant effect on the …

The Implications Of Artificial Intelligence In The Criminal Justice System, Natalie Garay

Honors Undergraduate Theses

This thesis focuses on artificial intelligence's recent implications on the criminal justice system regarding its admissibility as evidence in civil and criminal cases. One of the main concerns surrounding artificial intelligence is determining the validity of AI application; application refers to the accuracy "AI measures, classifies, or predicts what it is designed to" (Article: Artificial Intelligence as Evidence by Paul W. Grimm, Maura R. Grossman & Gordon V.Cormack.(https://scholarlycommons.law.northwestern.edu/cgi/viewcontent.cgi?article=1349&context=njtip). Privacy law will also be analyzed in this analysis. Is evidence recorded without the individual's consent or knowledge acceptable in determining an individual's guilt? This analysis will primarily focus on …

At The Heart Of Nursing: A Literature Review On Health Literacy Education In Nursing Curricula And Preparation For Patient Teaching Encounters, Samantha Garcia

Honors Undergraduate Theses

Background: Health literacy is defined as one’s ability to find, comprehend, and utilize information to make health decisions (Office of Disease Prevention and Health Promotion, n.d.). Globally, nursing students are exposed to the concept of health literacy during their degree-seeking years, yet no formal health literacy education exists across nursing curricula in pre-licensure programs at the associate and bachelor levels. This lack of standardization and non-emphasis of health literacy as a formal topic within education has contributed to poor provider performance and, in turn, low health literacy rates that may lead to suboptimal patient outcomes.

Significance: Studies have found that …

Ratón Pérez: A Translation Of The Spanish Tooth Fairy Legend, Sasmeta Giriraj

Honors Undergraduate Theses

The Ratón Pérez story is an essential landmark in the childhoods of many, especially in Latin American culture. The tale serves as a tool to help children with the anxiety and pain that may be associated with loss of their primary teeth and creates an exciting tradition for them to partake in. Despite the prevalence of this story among Hispanic populations, the last translation of it into English was by Ada Margarete Smith, Lady Moreton (1914). Given the large oral health disparity between the Hispanic population and other ethnic groups in the United States, a more updated translation may serve …

Motivations For Retaliatory Aggression On Social Media Among Borderline Personality Endorsers, Hannah Grimes

Honors Undergraduate Theses

Social media has become a popular way of connecting with people, but it has also led to an increase in cyber aggression. Borderline Personality Disorder (BPD) is a condition that is characterized by retaliatory aggression, difficulty in interpersonal relationships, and high impulsivity. Those who endorse BPD symptoms experience unstable interpersonal relationships and struggle to maintain connections with others which can lead to problematic behaviors on social media like retaliatory aggression. Understanding the motivations behind those behaviors can help inform the experiences of the diagnosed population, mitigate problematic behaviors, and facilitate healthy social relationships. This study aims to explore the motivations …

Masculinity And Political Discourse: A Critical Analysis Of European Leaders, Taylor R. Haycock

Honors Undergraduate Theses

This project examines how European leaders of autocratic and democratic nations engage with masculinity discourses in their public speeches. Do authoritarian leaders use masculinity in a different way than democratic leaders? I answer this question by completing a critical discourse analysis of speeches from Vladimir Putin, Recep Tayyip Erdoğan, Boris Johnson, and Emmanuel Macron, the leaders of Russia, Turkey, the United Kingdom, and France, respectively. The speeches were publicized from July 2019 to September 2022, when all four leaders were simultaneously in office. I found that a similar rhetorical strategy focusing on dominance and strength was used across regime types …

Shades Of Justice: Exploring Colorism In The Hispanic Community And Its Legal Battle For Equity, Christel A. Infante

Honors Undergraduate Theses

This thesis focuses on the racial disparity within the Hispanic and Latinx communities as injustices exist within the community and the workplace. Racial disparities in the United States have been a persistent and deeply rooted issue that has plagued the nation for centuries. Despite significant progress in civil rights and anti-discrimination legislation, disparities in areas such as education, employment, and criminal justice persist. Understanding the factors contributing to these disparities is essential for addressing systemic inequalities and fostering a more just society. The analysis of this thesis primarily focuses on the cases and ramifications of Hispanic persons within the workplace, …

Caring For The Caregiver: A Study On The Quality Of Life Of Informal Caregivers Of Aging And Elderly Adults With Down Syndrome, Isabel E. Latorre-Lagos

Honors Undergraduate Theses

This research studied the quality of life of informal caregivers of aging and elderly adults with Down syndrome. Prior research indicates some degree of deteriorating Quality of Life (QoL) for caregivers, however, there is no empirical research isolating the aspect QoL affected. This study seeks to research the following two questions: 1) What are the trends in the four domains that influence Quality of Life, both positively and negatively, of informal caregivers of aging and elderly adults with Down syndrome? and 2)What supports do caregivers of aging and elderly adults with Down syndrome want to improve their own Quality of …

Healthcare Disparities Among Hypermobile Spectrum Disorder And Hypermobile Ehlers-Danlos Syndrome Patients, Brooke A. Martinez

Honors Undergraduate Theses

Hypermobile Ehlers-Danlos Syndrome (hEDS) is the most common subtype of rare connective tissue disorder called Ehlers-Danlos Syndrome (EDS). Hypermobile Spectrum Disorder (HSD) is a connective tissue disorder that presents itself similarly to hEDS. Both disorders primarily affect individuals assigned to females at birth (AFAB), and symptoms range from joint instability, musculoskeletal pain, dizziness, fatigue, depression, and anxiety. Due to many factors like lack of education or attitudes among medical professionals (MPs), receiving a diagnosis of either of these conditions can be a challenging and grueling journey for patients. An online survey was conducted and distributed over social media platforms to …

Childhood Trauma, Stress, Gender, And Depression's Impact On Suicidal Behavior, Emily H. Mezni

Honors Undergraduate Theses

Suicide is one of the leading causes of death in young adults. Continuous prevention and intervention efforts throughout the world have been made to reduce suicide risk in this population. Two of the biggest known risk factors for suicide is childhood trauma, a traumatic event or events that occur during youth, and depression. Researching the impact childhood trauma and depression make in conjunction with other factors will help to increase knowledge of suicidal behavior. In this study, recent stress and gender will be factored with childhood trauma and depression severity to predict suicidal ideation and attempt. Recent stress is useful …

Reliable Detection Of Wnt7a Protein In Transfected Human Embryonic Kidney 293 Cells, Henry Okonkwo

Honors Undergraduate Theses

Fetal Alcohol Spectrum Disorders (FASDs) refer to a set of development abnormalities affecting a fetus that can result from prenatal alcohol exposure (PAE). Studies performed by the National Institute of Health estimate that the pervasiveness of FASDs may number as high as 1 to 5 per 100 school children. Congenital heart defects (CHDs) are a subset of these abnormalities and have been observed to occur in 38% of children with FASDs. While there is an association between PAE and CHDs, the exact molecular mechanism as to how it occurs remains unclear. A 2022 RNA sequencing study points to the Wnt7a …

Investigating The Role Of Glycemic Control In Cognitive Impairement Risk Among Elderly Individuals With Type 2 Diabetes: A Scoping Review, Julia Pessaia

Honors Undergraduate Theses

Type 2 diabetes mellitus (T2DM), presents a significant health burden globally, affecting millions of individuals, especially in the elderly population. While its association with cardiovascular diseases and cognitive impairments is well-documented, further research on the precise influence of glucose control on cognitive outcomes in elderly T2DM patients is necessary. This scoping review aims to address this gap by investigating the impact of HbA1c levels representing glycemic control on the risk of developing cognitive impairments in elderly patients with T2DM. A literature search was conducted on MEDLINE and eligible studies involved T2DM patients aged 60 or older, with documented cognitive function …

The Use Of Telehealth Evaluations For Diagnosis Of Autism Spectrum Disorder In Children Aged 0-7: A Literature Review, Teah L. Ruiz

Honors Undergraduate Theses

The following literature review was intended to review current research studies related to diagnostic evaluation using Telehealth for young children aged 0-7 seeking a diagnosis of autism spectrum disorder (ASD). The analyzed research created a comprehensive guide on the quality, quantity, and state of Telehealth research for ASD evaluation will result. Through the synthesis of available literature, the strengths, and weaknesses of different models of Telehealth ASD evaluation were assessed. The results of this literature review found that there is evidence to support Telehealth’s use in some aspects of evaluation, but not as a stand-alone methodology. Further research is required …

Assessment Of Quality Of Life Among Patients Undergoing Semaglutide Treatment For Weight Loss, Muhammad Sameed

Honors Undergraduate Theses

Purpose: The study aims to assess the Quality of Life (QoL) among patients undergoing semaglutide treatment for weight loss. The primary hypothesis is that patients’ QoL will improve after semaglutide treatment. This can be due to losing weight, having better physical and mental health, or due to the perceived betterment in life after treatment.

Introduction: Obesity is becoming more prevalent in America, and it has a huge effect on the person's medical conditions, life expectancy, and QoL. Though there has been a surge of treatments to deter the obesity rates in America from rising. One of the more popular and …

The Promise Of Graphic Medicine In Provider Training To Promote Mental Health, Prevent The Empathy Decline, And Improve Learning, Maeher Sukhija

Honors Undergraduate Theses

As medical students progress through their training, they experience a decline in empathy, mental health struggles, and difficulties in learning. The prevalence of depression, anxiety and burnout among medical students, along with the decline of empathy in medical students can impact their professionalism and quality of patient care as future physicians. This literature review shows how the integration of graphic medicine in provider training can address these problems, giving a new perspective on what medical education should look like. Thirty-three articles were found and reviewed by searching through the databases Academic Search Premier, PubMed, and Google Scholar, along with the …

Mapping Accessibility To Emergency Care Using Public Transportation, Bach Tran

Honors Undergraduate Theses

Intro: Public transit offers various advantages for both communities and individuals in terms of mobility and has the potential to serve as a practical alternative to private motorized transportation. Timely and convenient public transit becomes a lifeline for people who cannot access other types of transportation, especially when it comes to emergency care. Method: We built a private network analysis within ArcGIS Pro using coordinate data from hospitals and stand-alone emergency rooms as designated by the North American Industrial Classification System (NAICS) and public transit data from Orlando, FL. Establishing the accessible time as 30 minutes, we computed and visualized …

The Effects Of Exercise On The Immune System Of Older Adults, Brianna Tran

Honors Undergraduate Theses

The purpose of this study was to examine the effects of exercise on the immune system of older adults. Physical exercise has been known to affect one’s health positively. However, specific statistics relating to types of exercise intervention and older adults are dispersed. Autoimmune diseases are a lifelong disease that results in an overactive immune system, causing it to attack healthy cells. Which then leads to symptoms such as fatigue, pain, swelling, and digestive issues. This thesis includes systemic literature reviews that directly discuss the benefits of moderate-intensity exercise regarding the immune system of the elderly population. Results from this …

The Influence Of Intersectionality On Identity And Resilience, Stephanie Washburn

Honors Undergraduate Theses

Co-occurring multiple minority group membership (e.g., ethnic/racial minority and sexual/gender minority) has come to be referred as intersectionality. The purpose of this study was to explore if intersectionality is related to identity and resilience in undergraduate adults. The participant pool consisted of college students from a large metropolitan university in the Southeastern United States, (N = 340), who took an anonymous online self-report survey battery in exchange for course credit. Higher levels of resilience were associated with lower levels of identity distress. Further, identity commitment, but not identity exploration, predicted resiliency. Sexual/Gender Minority (SGM) individuals had lower resiliency than …

Palliative Care Integration Into Critical Care In People With Terminal Conditions, Arielle Westfall

Honors Undergraduate Theses

Palliative care is of value to the quality of life in people with terminal conditions when initiated early. The purpose of this literature review was to identify barriers to early initiation of palliative care consultation. The secondary purpose was to examine characteristics that prompt palliative care consultation. The TLC model of palliative care was used to explore palliative care in the critical care setting in people with terminal conditions. The concepts of the model support optimal palliative care as collaborative and comprehensive, with shared decisions made by the patient, practitioners, and loved ones. A literature review was conducted to identify …

Understanding Guardian Perceptions Of Whole-Foods Plant-Based Diets As Interventions In Pediatric Medicine, Vijay R. Luthra

Honors Undergraduate Theses

The obesity epidemic is widespread in American society, often affecting children who bear its consequences innocently. Due to a lack of nutrition knowledge, children rely on caregivers to meet their nutritional needs and instill healthy habits. This study examines parents' attitudes, knowledge, and behaviors, as well as perceived barriers to adopting a whole-foods plant-based diet (WFPD) for their children. Using a modified survey instrument by Morton et al., this study focused on parents and children regarding dietary choices. Participants were recruited from the waiting area of a pediatric clinic at the Medical College of Georgia between April and May 2023. …

The Effects Of Bilingualism And Trust On Digital Scam Susceptibility, Grace M. Casanova

Honors Undergraduate Theses

Trust is an essential component of social relationships and is connected to how we make informed decisions. Humans tend to use mental shortcuts to arrive to decisions, a strategy which may be exploited by scammers. As online scams have become more common, it is critical to understand factors that can influence appraisal of potentially untrustworthy sources. The present study focused on language, in the form of self-reported bilingualism, and its relation to scam susceptibility. Language is a factor that contributes to alterations in brain structure, cognitive performance, and cognitive control systems. Bilinguals show advantages in the form of increased synaptic …

Music Recommendation Using Exemplars And Contrastive Learning, Tina Tran

Honors Undergraduate Theses

The popularity of AI audio applications is growing, it is used in chatbots, automated voice translation, virtual assistants, and text-to-speech translation. Audio classification is crucial in today’s world with a growing need to sort and classify millions of existing audio data with increasing amounts of new data uploaded over time. In the area of classification lies the difficult and lucrative problem of music recommendation. Research in music recommendation has trended over time towards collaborative-based approaches utilizing large amounts of user data. These approaches tend to deal with the cold-start problem of insufficient data and are costly to train. We look …

Historical Legacies & Contemporary Anti-Americanism In Latin America, Ana Bello Marín

Honors Undergraduate Theses

Latin America is often cited as a prime example of historically rooted and deeply embedded opposition to the United States. There exists a prevalent assumption in the literature that suggests a legacy of foreign intervention can breed anti-Americanism. From this theoretical point of departure, we would expect individuals who lived through periods of intervention to express more negative opinions of the U.S. This thesis aims to explore whether historical legacies continue to live on and impact individual-level evaluations of the United States. By exploiting cross-country variation in the years and types of intervention, this study tests the empirical significance of …

Health-Outcomes Related To Smartphone Use In The College Student Population: A Scoping Review, Gregory Deglomine

Honors Undergraduate Theses

Objective: A scoping review was employed to consolidate what is currently being studied and reported on concerning interactions with smartphone devices and correlated negative health-outcomes, specifically within the college student population. We are specifically concerned with this population due to the unique demands of technology use coupled with free time use of smartphone devices. Information such as study focus, study design, and summarized results are be provided within this compilation of available data. Results: The existing data findings are heavily skewed in favor of a positive correlation between smartphone use and negative health-outcomes. Sampling 17,069 total participants across 41 studies, …