Digital Commons Network^™

Comparative Analysis Of Serum-Free Culture Conditions On Cell Proliferation And Extracellular Vesicle Production By Adipose-Derived Stem Cells, Ayna Ghulldu

Honors Undergraduate Theses

Adipose-derived stem cells (ADSCs) are promising candidates in regenerative medicine due to their proliferative capacity, self-renewal, and secretion of extracellular vesicles (EVs) that mediate intercellular communication. Serum-free media has been increasingly explored for MSC culture as it eliminates xenogeneic components, improving human therapeutic suitability. However, comparative evaluation of distinct serum-free formulations on ADSC proliferation and EV output simultaneously remains limited. This study compares a serum-containing medium to three proprietary serum-free media prototypes differing in composition, including the presence or absence of extracellular matrix proteins, to inform the optimization of culture conditions for clinical use. Proliferation, EV characteristics, and gene expression …

Examining The Results Of Revolutions In The Third World: A Case Study Of The Iranian, Libyan, And Nicaraguan Revolutions, Noah A. Mohammedelamien

Honors Undergraduate Theses

This thesis examines the post-revolutionary trajectories of Libya, Iran, and Nicaragua to explain why some Third World revolutionary projects preserve and use elements of their founding ideology while others fragment, personalize, or diffuse over time. Rather than focusing on the causes of revolution alone, it analyzes the durability of religious-socialist ideological continuity after revolutionary upheaval. Using a (MDSD) comparative historical and institutional approach grounded in primary and secondary sources, the study evaluates five key dimensions across the cases: religious-socialist ideological fusion, religious elite loyalty, popular religious mobilization, institutional embedding of ideology, and external pressure. The findings suggest ideological continuity is …

Noninvasive Monitoring Techniques: The Use Of Scat-Sourced Dna And Camera Traps To Monitor Mammalian Carnivore Species At The Ucf Arboretum, Zachary Montealegre

Honors Undergraduate Theses

The 800-acre University of Central Florida Arboretum Natural Lands functions as a conservation area, recreational space, and research site, making it essential to understand the ecological community it supports. Traditional wildlife monitoring methods such as mark-recapture and blood sampling can be effective but may stress animals or disrupt natural behaviors. To minimize these impacts, this study used non-invasive techniques, specifically scat-based DNA analysis and camera trapping, to assess carnivore species' presence. Two ecologically similar sites within the Arboretum were selected. Suspected carnivore scat was collected twice weekly over two months using both structured and opportunistic sampling. DNA was extracted, amplified, …

Repurposing Cyclin-Dependent Kinase Inhibitors For The Discovery Of Novel Antiplasmodial Compounds, Ritam Bhowmik

Honors Undergraduate Theses

Malaria remains a major global health burden with over 282 million cases annually and rising resistance to artemisinin-based combination therapies. Plasmodium falciparum, the most lethal malaria parasite species in humans, relies on tightly regulated cell cycle progression during replication within red blood cells. Cyclin-dependent kinases (CDKs) are central regulators of eukaryotic cell division and transcription, and several CDK-like enzymes in P. falciparum, including Pfmrk and PfPK6, are essential for parasite growth and structurally distinct from human kinases. This study evaluated whether commercially available human CDK inhibitors (CDKIs) targeting cancer pathways could be repurposed as novel antimalarial compounds. A library of …

Self-Reported Psychological Effects Of Rock Climbing In Adults On The Autism Spectrum, Brennan Gleason

Honors Undergraduate Theses

Background: Prior research has shown rock climbing to have considerable therapeutic potential through such mechanisms as boosting self-esteem, promoting mindfulness, and creating a supportive social community. (Liu et al., 2022, Osborne et al., 2025). Meanwhile, autistic adults experience mood disorders at a significantly higher rate than the general population; upwards of 54% are diagnosed with a psychiatric condition (Croen et al., 2015). Many of the issues negatively affecting autistic adults align with the benefits of rock climbing, including low self-esteem, inadequate social support, and anxiety.

Objective: This study aimed to find differences in mental health outcomes between autistic adults who …

Manuka Honey Modulates Oxidative Stress In Neuro2-A Cells Through Mitochondrial Regulation, Rachel Abramovici

Honors Undergraduate Theses

Manuka honey is known for its vital usage in wound healing, being an agonist towards fighting infections, and is an acting antioxidant [32]. Its main constituents are flavonoids and phenolic compounds, with methyl syringate (MSYR) being a major active ingredient. The specific compounds responsible for these antioxidant effects, particularly in the CNS, remain unclear. It is hypothesized that pre-treatment of mouse neuroblastoma cells with MSYR followed by hydrogen peroxide exposure will activate the AMPK/SIRT1/PGC-1a pathway, due to MSYR’s phenolic structure, and thus reduce oxidative stress and improve mitochondrial biogenesis. Hydrogen peroxide is a standard reactive oxygen species (ROS) treatment to …

Transforming Florida Chemistry Education: Exploring Information Literacy Strategies From Singapore, Han N. Le

Honors Undergraduate Theses

This study explores the applicability of Singapore’s information literacy (IL) strategies within Central Floridian higher education environments. Singapore’s national IL framework, supported by its Ministry of Education, integrates information and communication technology (ICT), professional development, and lifelong learning initiatives through a standardized, systemwide approach. In contrast, IL instruction in the United States is largely decentralized, often limited to one-time sessions or elective courses. To investigate the feasibility of adapting Singapore’s practices, surveys were distributed to faculty and librarians across Florida’s twelve public universities, yielding responses that highlighted varying levels of IL integration, limited institutional support, and minimal professional training related …

A Systematic Literature Review Of The Possible Negative Impacts Of Overconsumption Of Mass Media And Technology On Elementary-Aged Members Of Generation Z (1997–2012) And Generation Alpha (2013–2024), Ashya Y. Warren

Honors Undergraduate Theses

This thesis explores the possible negative impacts of overconsumption of mass media and technology on the elementary-aged members of Generation Z (1997-2012) and Generation Alpha (2013-2024). This research is aimed at establishing the relationship between excessive and uncontrolled exposure to digital media and cognitive, emotional, social, behavioral, and academic difficulties at a critical period of child growth. The purpose of this systematic literature review can be explained by the author's experience with technology overuse and professional interests as a future teacher, who should be prepared to help promote healthy childhood and development. The systematic literature review was based on peer-reviewed …

Impact Of Lifestyle Factors On Allergic Rhinitis Symptoms And Quality Of Life Among College Students, Lina Saint-Hilaire

Honors Undergraduate Theses

This study aims to examine the influence of certain lifestyle factors on the presentation of allergic rhinitis symptoms and the quality of life of college students. Factors of interest include residential setting, household cleaning habits, age of symptom onset, and exposure to household pets. Additional analysis includes assessment of the impact of allergic rhinitis symptoms on sleep. Using a cross-sectional survey design, student responses were self-reported through a paper survey distributed during tabling days at the University of Central Florida (UCF) main campus. Eligible participants had to be 18 years or older and current UCF graduate and undergraduate students. Survey …

Slay Her: The Rhetoric Of Violation In Buffy The Vampire Slayer, Lea N. Wright

Honors Undergraduate Theses

This research draws on feminist theory and monster theory to perform a close rhetorical analysis of incidents in the television show Buffy the Vampire Slayer (Buffy) where female characters are violated physically, psychologically, and/or sexually. Buffy is one of the most-analyzed television shows of all time, with a particular emphasis on the show’s engagement with feminism; however, the issue of violation has received little scholarly investigation despite multiple instances of it within the show. Through examining the rhetorical elements (such as dialogue, camerawork, body language, and character response) that surround incidents of violation, this research reveals that Buffy …

Gen Z Perspectives On Mental Health Service Interaction: A Qualitative Content Analysis Of Reddit Discourse, Victor A. Aguiar

Honors Undergraduate Theses

Compared to prior generations, Generation Z engages with mental health and mental health service interaction in distinct ways, frequently using social media platforms to share experiences, concerns, and opinions. Previous research has examined mental health discourse on Reddit; however, much of this work relies on inductive thematic approaches and offers limited focus on mental health service interaction and the factors influencing utilization. Guided by the Theory of Planned Behavior (TPB), this study examines how Generation Z discusses mental health service use through online discourse. Public Reddit posts authored by users identifiable as Generation Z, based on self-reported age, school enrollment, …

Social Determinants Of Health Affecting Cardiovascular Health Among South Asian Americans, Ann Mary Thomas

Honors Undergraduate Theses

Background: South Asian Americans experience disproportionately high rates of cardiovascular disease, yet the social determinants contributing to these disparities remain understudied.

Objective: This systematic review examines the role of social determinants of health (SDOH) in shaping cardiovascular outcomes among South Asian Americans.

Methods: A systematic literature search was conducted across PubMed, MEDLINE, and Web of Science using predefined search terms related to South Asian populations, cardiovascular health, and SDOH. The review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 reporting guidelines, and study screening and management were performed using Covidence. A total …

Impact Of Senescence On Breast Cancer Outcomes, Gracie Sous

Honors Undergraduate Theses

Cellular senescence is a biological process in which damaged cells exit the cell cycle while remaining metabolically active and accumulating within tissues. Senescence plays a complex role in breast cancer progression, largely through the secretion of senescence-associated secretory phenotype (SASP) factors. These factors include a broad range of inflammatory cytokines, chemokines, and signaling molecules that can influence the tumor microenvironment.

Studies suggest that senescence may significantly promote cancer metastasis. Therefore, this study aims to investigate the genes involved in cancer progression and to improve understanding of how SASP is regulated, which is critical for improving breast cancer outcomes. The central …

Investigating The Interaction Of Gram-Positive Lactobacillus Species With Mucin In The Context Of Barrett's Esophagus, Ritisha Suresh

Honors Undergraduate Theses

Gastroesophageal Reflux Disease (GERD) can progress to the precancerous Barrett’s Esophagus (BE) condition, in which the normal esophageal squamous epithelium is replaced with a columnar epithelium containing goblet cells. Mucins, sticky substances, are secreted in response to bile acid exposure during reflux episodes to protect the esophageal epithelium. Goblet cells secrete these mucins, which can also scaffold microbial colonization. Probiotic Lactobacillus bacteria can use glycosidase enzymes to process mucin and metabolize them into their component sugars (glycans). This project aims to identify the role of the Lactobacillus-mucin interaction in BE, as glycan availability could confer an advantage to Lactobacillus …

Unmasking Impression Management: Large Language Models For Detecting Socially Desirable Responding In Open-Ended Situational Judgment Tests, Barret Vermilion

Graduate Studies Theses and Dissertations 2026

Socially desirable responding (SDR) — the tendency to present oneself in an overly favorable light — remains a persistent validity concern in industrial-organizational psychology. Contemporary theory frames SDR as multidimensional, distinguishing agentic impression management (AM; inflating competence, dominance, and achievement) from communal impression management (CM; inflating warmth, cooperation, and prosocial qualities). Existing measures of AM and CM rely on self-report, which captures these constructs only at the level of generalized trait-like tendencies rather than as they naturally unfold in applicants' own language. This dissertation proposes a text-based alternative: detecting AM and CM in open-ended situational judgment tests (SJTs) of Big …

Do Emerging Social Media Platforms Shape The Gender Gap In Surveillance Political Knowledge?, Saskia Papsova

Graduate Studies Theses and Dissertations 2026

Abstract

Research shows that men consistently score higher than women on standard political knowledge measures, but as Americans increasingly obtain political information through social media, it is unclear whether different platforms affect this gender gap. This study investigates whether social media platforms shape the gender gap in surveillance political knowledge—knowledge of current political facts and contested claims circulating in the contemporary information environment, and which platforms have the biggest impact. Using data from the ANES 2020 Social Media Study, I estimate weighted OLS regression models testing whether platform-specific usage is associated with surveillance political knowledge and whether these associations differ …

The Effects Of Episodic Facilitation And Immersion On Memory Formation During Learning Of An Exterior Preflight Inspection Procedure, Nathan A. Sonnenfeld

Graduate Studies Theses and Dissertations 2026

This research examined the use of episodic facilitation—instructional elements aligned with episodic memory (EM) processes—to affect learners’ memory of simulation training for an aviation procedure. Despite its assumed benefits in industry and theory, virtual reality (VR) has shown limited advantages over conventional media for training procedures, in part because prevailing frameworks emphasize semantic and procedural outcomes, leaving memory of training experiences as events underexamined. To address this gap, this work advances human factors research by examining EM as a design consideration, an outcome, and an explanatory mechanism for how simulation training experiences are remembered. Grounded in theories of EM and …

The Attention Safeguard Models: Governing Digital Harm Without Restricting Lawful Speech, Delante Clark

Graduate Scholarship and Creative Works

Digital platforms increasingly govern contemporary social, civic, and psychological life through systems optimized for attention capture, amplification, and monetization. While lawful expression remains protected under the First Amendment, the infrastructural mechanisms that determine how speech circulates have produced a range of attention‑based harms, including cyberbullying, engagement farming, compulsive doom scrolling, emotional dysregulation, and civic polarization. This research paper introduces the Attentional Safeguards Model (ASM), coined and formalized by Delante Clark, as a novel governance framework that mitigates such harms by regulating systems of amplification rather than restricting expression itself. Building on attention economy theory, technological mediation, constitutional free‑speech doctrine, …

Socialization Interventions For Older Adults In Assisted Living Facilities: A Systematic Review, Anoop S. Muvva

Honors Undergraduate Theses

Older adults, defined as individuals over the age of 65, are a growing population in the United States, with projections estimating this group will reach approximately 80 million persons by 2050. Over 90% of older adults are diagnosed with a chronic condition, which can make it difficult to carry out the activities of daily living. As a result, some older adults reside in assisted living facilities, where dedicated staff provide daily support. However, issues in the delivery of care within these settings, including unmet socialization needs and complications among care staff, may contribute to social isolation. Programs designed to address …

Illuminating Those Who Lurk In The Shadows: An Examination Of The Use Of Psychological Profiling In Identifying Violent Criminals In The Modern Age, Skylar R. Holmes

Honors Undergraduate Theses

This study examines the role of psychological profiling in apprehending violent criminals. Psychological profiling involves analyzing behavioral patterns at crime scenes, exploring the relationships between victims, and identifying characteristics and tendencies of offenders. It is currently used by many law enforcement agencies across the country to narrow down a pool of potential suspects and direct researchers, making the most of the limited manpower available. There is, however, a significant limitation in the literature and available evidence that suggests its tenets may be based on intuition and anecdotal evidence purported by investigators, subject to internal bias and thus should not be …

Casual And Confused: Engagement In Non-Committal Sexual Relationships And Its Contributions To Depression And Self-Esteem Struggles Among Young Adults, Sofia A. Marasco

Honors Undergraduate Theses

Non-committal sexual relationships such as hook-ups, friends-with-benefits (FWB/FWBR), and situationships have become increasingly common among young adults and have generated substantial discourse on social media. Despite the rise in modern relationship dynamics and new terminology (i.e., “situationships”), these relationship categories have not been adequately represented in psychological research. The present study examines whether engagement in non-committal relationship types is associated with differences in self-esteem and depressive symptoms compared to committed romantic relationships. Using Bowlby’s Attachment Theory and the Big Five Personality Model, this research also explores whether common interpersonal patterns, attachment styles (anxious and avoidant), and personality traits predict relationship …

An Investigation Of The Impact Of Gender And Race On The Stigmatization Of Borderline Personality Disorder, Joshua Samet

Honors Undergraduate Theses

Stigma surrounding mental health reduces treatment-seeking behaviors and can worsen symptoms. Research on stigma surrounding borderline personality disorder (BPD) has shown that race and gender can impact the nature of the stigma associated with the disorder; however, less is known about the interaction between the two. This study investigated if stigma varies when considering both the race and gender of the stigmatized individual simultaneously. 218 undergraduate students read one of four vignettes describing either a Black male, White male, Black female, or White female, then completed the Attribution Questionnaire-20 (AQ-20) stigma scale. The results indicate that there is a statistically …

Perceptions, Expectations, And Attitudes About Adolescent Telepsychiatry Among Indian American Family Caregivers, Udayvir Jalf

Honors Undergraduate Theses

Adolescent mental health concerns have risen sharply in the United States. The COVID-19 pandemic marked a significant turning point in mental health care access, with telehealth having become a central mode of care delivery. With adolescent telehealth, caregiver involvement has shown to improve treatment adherence and outcomes. Little is known, however, about how Indian American caregivers experience and navigate their adolescent’s virtual mental health care. This qualitative study investigated the perceptions, expectations, and attitudes of Indian American family caregivers regarding adolescent telepsychiatry and caregivers’ involvement. In depth semi-structured interviews were conducted with Indian American caregivers of adolescents who completed at …

Artificial Elections: How Artificial Intelligence Can Affect Elections And Decide Our Future, Ryan D. Granger

Honors Undergraduate Theses

This thesis examines the growing role of artificial intelligence (AI) in democratic elections, highlighting both its transformative potential and its associated risks. Drawing on a qualitative analysis of existing literature, the study explores how AI is increasingly integrated into political campaigns, election administration, and voter engagement. Key benefits include enhanced data analysis, personalized political messaging, and improved efficiency in campaign operations. AI also supports real-time fact-checking and more accurate vote tabulation, which can strengthen transparency and trust in electoral processes. However, the thesis emphasizes that these advantages are accompanied by significant challenges. AI technologies enable the rapid creation and dissemination …

Industrial And Organizational Psychology Researchers’ Positive And Negative Experiences With The Peer-Review Process, Alexa Weaver

Honors Undergraduate Theses

Peer review plays a critical role in advancing the field of psychology; however, limited empirical research has examined psychologists’ experiences with the peer review process. The present study investigated both positive and negative peer review experiences among industrial and organizational (I/O) psychologists and assessed the prevalence of specific reviewer behaviors. A two-phase survey design was administered via Qualtrics. Study 1 employed open-ended questions to identify recurring themes in researchers’ experiences with peer review. Thematic analysis revealed distinct positive and negative patterns of reviewer behavior, which informed the development of Study 2.

Study 2 quantitatively assessed the prevalence of behaviors associated …

Examining The Barriers To Healthcare Among Native Hawaiian And Pacific Islander Populations Living In Hawaii, Gracie L. Kaye

Honors Undergraduate Theses

The state of Hawaii was annexed by the United States in 1898, and served as a starting point from which the U.S. influenced Hawaii's socioeconomic conditions and healthcare access. The literature review examines healthcare views and outcomes among Native Hawaiian and Pacific Islander residents, utilizing various tools and resources to investigate how these factors have impacted overall health statistics and the reasons behind these trends. Results found that the western colonization of the island and the disease outbreaks led to an initial mistrust of “western ideas.” Additionally, due to long-standing cultural beliefs, there is a natural preference for traditional cultural …

Interaction Of The Dap-10 Fluorescent Light-Up Aptamer With An Environment-Sensitive Dye, Crystal Violet, Marina Tsukanova

Honors Undergraduate Theses

Crystal violet (CV) is an environment-sensitive dye whose fluorescence is strongly influenced by microenvironment polarity and viscosity, increasing markedly when rotational and vibrational motions are restricted. While the fluorescence enhancement of CV by fluorescent light-up aptamers (FLAPs) has been noted in literature, the specific binding interactions between CV and aptamers in the DAP-10 family have remained under-investigated.  The objective of this work is to elucidate the binding site interactions between CV and the DAP-10-42 FLAP. It is hypothesized that positions 34 and 35 of the aptamer’s sequence reside in a proposed quadruplex-duplex junction that form the dye-binding pocket of DAP-10 …

Expanding Assessment Of Adverse Childhood Expereneces(Aces) To Include Childhood Disabilties And Medical Trauma., Cassidy E. Chergi

Honors Undergraduate Theses

Adverse Childhood Experiences (ACEs) are considered a fair predictor of future physical and mental health outcomes. However, historically, the ACEs framework has not fully incorporated chronic stressors associated with childhood physical disabilities and health conditions. This study proposes an expansion of ACEs to include serious childhood medical issues and events as well as disability-related adversity—such as early experiences of functional limitations, social adversity, and system-wide barriers. This study also explores the correlation between these serious medical issues and disability-related adversity in childhood and psychological issues in early adulthood, including signs of trauma, depression, and anxiety. Understanding these relationships can contribute …

Analyzing Early Medieval Perspectives Of Fetal Development, Nivedha Srinivasan

Honors Undergraduate Theses

This thesis examines early medieval perspectives of fetal development by analyzing two manuscripts: British Library, Cotton Tiberius A III and Leiden University, Vossianus lat. Q69. This study will investigate how knowledge of pregnancy was shared throughout England before the establishment of universities. Interest in medieval reproductive language has piqued in importance in recent years, especially due to modern legal debates surrounding reproductive rights. By examining descriptions of the nine months of fetal development in these two manuscripts, as well as in widely known earlier medical texts like Pliny’s Natural History and Vindicianus’ Gynaecia, this research explores how monastic writers in …

Listening To The Cemí: An Exploration Of Taíno Spirituality Culture Through Artifact Analysis And Digital Archives, Jordan G. Richardson

Honors Undergraduate Theses

My research explores the evolution and continuity of Taíno spirituality culture across five centuries through artifact analysis and digital archives. While Spanish imperialism in the 15th century devastated Taíno populations and traditional craft production, I find that Taíno spirituality was not eradicated but rather adapted its mode of expression. The shift in medium from primarily pre- and peri- physical cemí artifacts (carved from wood and stone) to contemporary digital representations (online archives, blog posts, YouTube videos) illustrates two things: a) strategic integration of Taíno technological use to preserve spiritual practices while reestablishing cultural connectivity through education, community, and resistance movements, …