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The Scoop, Vol. 11 Issue 10, January 2025, Health Sciences Library

Volume 11

Latest news and updates from the Health Sciences Library in our monthly newsletter for January 2025. Please see page 2 for a text-only version of this issue!

Voicing The Violence: Carmen Maria Machado's Contribution To A Queer Archive, Audrey C. Bryant

Honors Undergraduate Theses

This project analyzes In the Dream House (2019) alongside “The Husband Stitch” and “Eight Bites” from the collection Her Body and Other Parties (2017) by Carmen Maria Machado. The first, a memoir, details Machado’s personal experience with domestic abuse between partners who share a female gender identity; the latter is a collection of short stories outlining everyday violations made against women. Scholars have discussed these works with specifications including female domestic horror, Machado’s use of retellings, and domestic violence and abuse. This project fills a gap in the discourse by intersecting and connecting queer theory with archival studies to support …

Effects Of Invigorating And Relaxing Music On Heart Rate, Blood Pressure, And Heart Rate Variability, Matthew Joshua Faur

Honors Undergraduate Theses

Heart-rate variability (HRV) has been documented to correlate with several health measures, including autonomic nervous system longevity and athletic performance (Zulfiqar, 2010). While increasing age does not affect heart rate, there is a steady decline in HRV, which is a biological marker of aging and the decline of autonomic nervous system function. Furthermore, men who exercise regularly tend to have increased HRV, suggesting a mitigation of the typical age-dependent loss of HRV (Kristal-Boneh et al., 1995). Previous studies have suggested that music may have a physiological effect (e.g., fluctuating vitals, emotional changes) on cardiovascular parameters. However, little is known about …

Associations Between Brain White Matter Hyperintensities And Diet Quality In Cognitive Aging: A Cross-Sectional Assessment, Carla V. Urdaneta

Honors Undergraduate Theses

Leukoaraiosis, or White Matter Lesions (WMLs)/White Matter Hyperintensities (WMHs), are often considered markers of aging and neurodegeneration. White matter hyperintensities appear as lighter, hyperintense regions on T2-weighted fluid-attenuated inversion recovery (FLAIR) magnetic resonance imaging (MRI) scans and are physiologically characterized as demyelination and axonal loss reflected as microvascular lesions in cerebral white matter (Marseglia et. al., 2019). These anatomical landmarks are most seen in MRIs of elderly individuals. They can be associated with aging and cognitive decline, including affected frontal lobe function and episodic memory in the form of delayed recall performance and are linked to several cardiovascular risk factors, …

Does Money Matter? An Analysis Between Per-Student Funding And Its Link To Student Achievement In Florida, Chloe Zwetschkenbaum

Honors Undergraduate Theses

This study examined the relationship between per-student funding and student achievement within four counties in the state of Florida (Clay County, Duval County, Flagler County, and St. Johns County) and whether higher per-student funding resulted in higher student achievement. Florida recently changed from the usage of the Common Core Standards to the Florida Benchmarks for Excellent Student Thinking (B.E.S.T.) and from the Florida State Assessment (FSA) to the Florida Assessment of Student Thinking (F.A.S.T.) test in 2022 (Sabina, Hartikka, and Viola, 2023). This research focused funding on the results of the F.A.S.T. test and the per-student funding of each district …

A Review Of The Utilization Of Comics In Research And The Potential For Graphic Medicine Integration In Health Science Communication, Nagatarang Nimmathota

Honors Undergraduate Theses

Communication is a vital part of research, both during its conduction and the dissemination of its findings. This can be difficult to achieve due to factors like knowledge disparity, technical jargon, and differing backgrounds. This narrative literature review draws from databases like PubMed, ScienceDirect, and others to examine the current utilization of graphic medicine in research and its effects on health research communication. This review found that the integration of graphic medicine can help alleviate those issues by simplifying complex topics into engaging visual narratives or comics for consumption by research participants and the public. Additionally, the use of graphic …

Comparative Semiotic Analysis Of Non-Verbal Communication: Apis Mellifera Waggle Dance And Human Kinesic Signaling Systems, Nishtha Tikalal

Honors Undergraduate Theses

There are many parallels between two seemingly disparate forms of non-verbal communication: the waggle dance of Apis mellifera (honeybees) and human kinesic signaling systems. Through a comparative semiotic analysis, this research aims to conduct a comparative semiotic analysis, investigating structural and functional similarities between these communication methods, challenging anthropocentric assumptions about meaning making in the natural world. This research employs a meta-synthesis approach, drawn from a methodological literature review to examine historical representations of bee-human relationships, semiotics of non-verbal communication, and the specific mechanisms of the waggle dance and human kinesics. This methodology involves systematic categorization and analysis of extracted …

Respiratory Cycle Influence On Lumbosacral Muscle Function: A Tensiomyographic Analysis, Anthony Trombetta

Honors Undergraduate Theses

Introduction:

Tensiomyography (TMG) has significant potential in examining muscle functionality while evading the limitations found in other methods muscle analysis. Specifically, the erector spinae and other lumbosacral muscles can be analyzed with little challenge. Such analyses include data on muscle displacement (Dm), delay time (Td), contraction time (Tc), half-relaxation time (Tr), and sustain time (Ts). Of these parameters, the most evaluated and with the highest level of reliability are Dm, Td, and Tc. However, stiffness of the lumbar spine and lumbosacral muscles fluctuates throughout the respiratory cycle. These fluctuations may pose an issue when examining the functionality of muscles. This …

Parisians' Perceptions Of The 2024 Olympics: A Mixed-Methods Analysis Of Local Attitudes Towards Housing Epidemics Using Social Exchange Theory, Place Attachment, And Media Framing Theory, Tyler Borges

Honors Undergraduate Theses

The Paris 2024 Olympics introduced significant socio-economic transformations to the city, particularly in the areas of housing policy, urban development, and community displacement. This study examines Paris residents' perceptions of these changes using a mixed-methods approach that integrates sentiment analysis and media framing analysis. The research is guided by Social Exchange Theory (SET), Place Attachment Theory, and Media Framing Theory to understand the relationship between public sentiment, urban transformation, and media narratives. Findings indicate that the perceived effects of the Paris 2024 Olympics on its host city were overwhelmingly negative, with consistent concerns centered on housing insecurity, displacement, and a …

The Association Between Parental Bipolar Symptoms And Offspring Identity Formation: The Role Of Parental Attachment And Emotion Regulation, Alexa D. Loonam

Honors Undergraduate Theses

Identity development involves integrating various aspects of oneself into a unified self-concept; however, maladaptive identity formation can lead to negative mental health outcomes (Berman & Weems, 2016). Growing up with a caregiver exhibiting unpredictable behaviors may hinder this process, leaving children vulnerable during this critical stage (Schwartz & Petrova, 2018). The current study evaluated how bipolar symptoms among parents may impact one’s identity. College students (N = 399) completed an anonymous online survey battery for course credit. Results revealed that parental bipolar symptoms were positively correlated with ruminative identity exploration, identity distress, disturbed (unstable) identity, and lack of identity, …

Cannabis Use And Functional Independence Among Older Adults: The Health And Retirement Study, Jade Alaine Perry

Honors Undergraduate Theses

As people age, negative cognitive effects become more common, and the likelihood of chronic disease diagnoses increases. Many older adults suffer from one or more chronic health issues that have serious impacts on both their mental and physical health. Chronic pain is also known to increase in prevalence as we age. Opioid use to treat chronic pain among older adults is worrisome due to the likelihood of drug-drug interactions due to polypharmacy and the risk of problematic opioid use that can lead to overdose. Cannabis use both medical and recreational has become more acceptable among the aging adult population in …

Tools And Trends: An Analysis Of Maya Dental Modification, Channing M. Cook

Honors Undergraduate Theses

The ancient Maya practiced dental modification, intentionally filing, incising, and inlaying stones into the front teeth, potentially to display identity and status. The literature surrounding Maya dental modification tends to overlook mechanical aspects of the process, and many studies approach dental modification through limiting or destructive means. Optical microscopy presents an adaptable, cost-effective option for closer inquiry. Preliminary research suggests the process of dental modification leaves distinct patterns of tool use, depending on style, that can be identified through optical microscopy. The sample selected includes 25 incisors and canines from 14 Classic period Maya individuals from Altun Ha, representing 12 …

The Impact Of Religiosity On Political Knowledge Among Youth Voters, Norah Sackett

Honors Undergraduate Theses

As political engagement trends among young voters have continued to shift in the United States' political atmosphere, understanding the cognitive factors that influence these decisions is becoming increasingly important. Political efficacy, or the feeling that individual political action can impact the political process, impacting their civic duties, has long been regarded as a key determinant of an individual's political engagement. This study investigates how young voters' understanding of prominent political arguments relates to their sense of political efficacy, with a specific lens on individual religiosity.

Through an examination of this relationship between religiosity and overall comprehension of political arguments, this …

Effects Of Resistance Exercise On Post Stroke Patients: Systematic Review Of The Literature, Jeslin Patel

Honors Undergraduate Theses

Individuals who suffer from post-stroke effect face loss of function in mobility and quality of life. Mobility issues lead to changes in walking patterns, strength ability, daily independence, and more. Resistance training is an effective rehabilitation method used to test improve recovery by enhancing well-being, reducing spasticity, and increasing control. The purpose of this study was to explore the effects of resistance exercise on post-stroke patient's recovery and return to activities of daily living. A systemic literature review using databases, key terms, and various strategies. Databases used consisted of UCF Libraries, PubMed, Google Scholar, SagePub, Medline, ScienceDirect, and EBSCOhost. These …

Digital Recess, Screen Time Split: The Impact Of Online Schooling On Recreational Screen Time And Their Dual Impact On Anxiety, Meagan Allender

Honors Undergraduate Theses

This study explores the influence of online schooling, anxiety, and recreational screen time in college aged students. Previous studies have shown a positive correlation between screen usage and anxiety scores, assessing either online school or total screen time on anxiety. However, no study had looked at the correlation between online schooling and recreational screen time, nor had any study assessed both their effects on anxiety at the same time. Using a sample of 71 participants, a bivariate regression was conducted to evaluate the correlation of each type of screen time with one another, then another regression was run to assess …

Users' Trust Perceptions Of Ai Search Results, Leilani J. Cordoves

Honors Undergraduate Theses

Utilizing a repeated measure design, this experiment analyzes users’ perceptions of artificial intelligence embedded within search engines compared to traditional linked search engines in various contextual situations. The purpose of this study is to find the differences in confidence for differing search methods and the variables of trust that lead to these perceived differences. Using screenshots of AI overview search results and linked search results, we asked participants questions of confidence and human-computer trust to gauge their perceptions of the varying search methods. We find evidence of a significant interaction effect in confidence scores between the search method and the …

Lost Innocence, Mateo Valdivieso

Honors Undergraduate Theses

Human trafficking is defined as involving “force, fraud, or coercion to obtain some type of labor or commercial sex act” (U.S. Department of Homeland Security). It disproportionately affects vulnerable populations, particularly children within the U.S. welfare system. This research aims to analyze the characteristics of this system that produce vulnerabilities in welfare children that heighten their risk of being trafficked. The study focuses on socio-economic, psychological, and environmental vulnerabilities, examining how these factors, combined with increased internet accessibility, exacerbate the risks of trafficking. Using a qualitative approach, the research uses secondary data from peer-reviewed journal articles, government reports, and reputable …

Investigating The Effects Of A Psychoplastogen On Depressive-Like Behaviors In Huntington Disease Model Mice, Kaleigh M. Hanley

Honors Undergraduate Theses

Huntington Disease (HD) is a neurodegenerative disorder caused by an expansion in the trinucleotide CAG repeat on exon 1 of the huntingtin gene. In HD one of the first symptoms is often depression. In cases where SSRIs fail, treatments for treatment-resistant depression often become a patient’s only option. These rigorous treatments, such as electroconvulsive therapy, are not suitable for this patient population as it can worsen motor symptoms. In order to search for potential alternatives, we queried whether depressive-like behavior could be reduced in Hu97/18 and Q175FDN HD mice by administering tabernanthalog, a non-hallucinogenic psychedelic analog. Our study is not …

Comparative Efficacy Of Hallucinogens In Treating Mood Disorders Through A Meta-Analysis Of Symptom Reduction, Dosage, And Duration, John Marco D.F. Muniz

Honors Undergraduate Theses

Background: Hallucinogens including psilocybin, lysergic acid diethylamide (LSD), ketamine, N,N-dimethyltryptamine (DMT) (as ayahuasca), have re-emerged as potential rapid-acting treatments for mood disorders. We conducted a meta-analysis of placebo-controlled trials evaluating their efficacy in depression and anxiety disorders. Methods: A systematic review identified 12 trials (Total ≈ 670) meeting inclusion criteria (randomized, placebo-controlled). Data on Cohen’s d and Hedges’ g effect sizes for depression- and anxiety-related outcomes were extracted. We computed pooled effect sizes (weighted by sample size and inverse variance), performed subgroup analyses by drug, diagnosis, follow-up duration, and outcome measure type, and assessed heterogeneity (I², Q …

Effect Of Metal Ions On The Reactive Oxygen Species Scavenging Capabilities Of Cerium Oxide For Biological Applications, Agastya Mittal

Honors Undergraduate Theses

Ceria nanoparticles' capabilities to defend cells against oxidative stress through superoxide dismutase activity are well-documented. Ceria nanoparticles demonstrate a ratio between 3⁺/4⁺ oxidative states on the surface of the particles to exhibit oxygen vacancies, a feature that allows these particles to scavenge Reactive Oxygen Species (ROS) in times of Oxidative Stress. Oxidative stress arises from many wounds in the body, such as wounds in the skin, and can have significant impacts on the health of an individual. Even when receiving treatment for the skin wound, ROS can circulate from around the wound, be generated from an imbalance …

Optimization Of L-Citrulline Production In Corynebacterium Glutamicum, And The Effect Of The Human Small Intestine Environment, Simran S. Ghulldu

Honors Undergraduate Theses

L-citrulline is a crucial amino acid involved in nitric oxide production, which supports cardiovascular health, physical performance, and intestinal well-being. Nitric oxide deficiency is linked to conditions like hypertension, highlighting the need for efficient L-citrulline production. This study attempts to enhance L-citrulline synthesis in Corynebacterium glutamicum, a bacterium widely used in industrial amino acid production, as well as test a The hypothesis is that overexpressing carAB, which encodes carbamoyl phosphate synthetase, will increase carbamoyl phosphate levels and boost L-citrulline production. Two C. glutamicum strains were used: a wild type and the CRBG strain, which has mutations that promote …

A Time Series Analysis Of The Macroeconomic Indicators, Mia Houston

Honors Undergraduate Theses

Understanding inflation—particularly across regions and categories—is crucial for effective policymaking, strategic business decisions, and safeguarding vulnerable populations, as it highlights the diverse drivers and impacts of price changes within the economy. This has become increasingly crucial in recent years between the volatile inflation conditions introduced by the COVID-19 pandemic, energy price shocks, and renewed trade tensions and tariffs. This thesis analyzes 77 U.S. monthly inflation time series from 2003 to 2023 using two forecasting approaches: an elementwise Seasonal Autoregressive Integrated Moving Average (SARIMA) model and a Factor-Augmented Vector Autoregressive (FAVAR) model. The data obtained from the Bureau of Labor Statistics …

Optimizing Crispri Gene Silencing Of Putative Drug Targets In Mycobacterium Abscessus, Max Ivanov

Honors Undergraduate Theses

Among nontuberculous mycobacteria (NTM), Mycobacterium abscessus (Mab) poses a particular threat to patients with cystic fibrosis and chronic obstructive pulmonary disease due to the lung damage and higher mortality rate it causes. Current treatments involve prolonged multi-antibiotic regimens that are often ineffective, highlighting the need for new drug targets.

The CRISPR Interference (CRISPRi) system uses a deactivated Cas9 protein (dCas9) to enable inducible gene silencing, offering a potential approach to identifying new targets. Genes that lead to a loss of Mab viability when silenced are considered essential, an important attribute of potential drug targets. While CRISPRi has shown …

Synthesis And Characterization Of Multifunctional Cerium Oxide Containing Nanoparticles For Biomedical Applications, Ishaan Patel

Honors Undergraduate Theses

This study presents the synthesis and comprehensive characterization of a novel core-shell nanoparticle composed of a maghemite (γ-Fe₂O₃) core and a europium-doped cerium oxide (EuCNP) shell, developed for potential use in cancer theranostics. Using a co-precipitation method, Fe₂O₃–EuCNP core-shell nanoparticles were synthesized and compared against control samples of CNPs, EuCNPs, and Fe₂O₃. A variety of characterization techniques, including UV-Vis spectroscopy, fluorescence spectroscopy, TEM, XRD, XPS, DLS, TGA, and DSC confirmed the successful synthesis of core-shell architecture and europium doping. Moreover, Fe₂O₃–EuCNPs demonstrating strong colloidal …

Investigating The Role Of Prostasin In Angiogenesis: A Chorioallantoic Membrane Model Approach, Zaima Aline

Honors Undergraduate Theses

Prostasin, also known as PRSS8 or CAP1, is a glycosylphosphatidylinositol (GPI)-anchored extracellular serine protease involved in various physiological and pathophysiological processes. Prostasin expression is observed during key phases of trophoblast invasion and placental development, critical steps in embryo implantation in Rhesus monkeys. This suggests a role for prostasin in extracellular matrix remodeling and tissue invasion, both essential for a healthy pregnancy. Moreover, prostasin appears vital for development as studies in mice show that a germline knockout of the gene leads to significant placental defects and eventual embryonic death, highlighting its importance in vascular and structural development within the placenta.

Building …

Examining The Effect Of A High Fat Diet On The Expression Of Adipokines In A Murine Model Of Barrett's Esophagus, Saagar A. Shah

Honors Undergraduate Theses

Chronic acid reflux results in injury to the esophagus and the development of Barrett’s Esophagus (BE). BE elevates the lifetime risk for a patient to develop Esophageal Adenocarcinoma (EAC). Clinically, one of the main risk factors for BE and EAC is obesity, which alters the secretion of inflammatory cytokines by adipocytes, also referred to as adipokines. Conflicting reports have been made to the expression of adipokines and their receptors in the progression to esophageal cancer. Utilizing an inflammation-based mouse model for BE, we hypothesize that alterations in the expression of adipokines and their receptors favor an inflammatory environment associated with …

Unravelling The Role Of Two-Component Systems In Mycobacterium Abscessus, Andrea C. Molero Perez

Honors Undergraduate Theses

Mycobacterium abscessus (Mab) is an emerging pathogen within the nontuberculous bacteria (NTM) which poses a threat due to its complex multi-drug resistance and opportunistic nature. It is predicted that only 45.6% of patients will have successful treatment, with immunocompromised and cystic fibrosis patients being the most threatened. Moreover, investigating new treatment approaches is key to responding to this public health issue. Two-component systems (TCS) are regulatory pathways that play a pivotal role in bacterial survival and virulence. These systems are composed of a sensor histidine kinase (HK) and cognate response regulator (RR) protein that senses environmental cues and triggers specific …

The Association Between Implicit Bias From Healthcare Providers And Postpartum Depression Among Black Women., Chelsea T. Costa

Honors Undergraduate Theses

Postpartum depression is one of the most common issues that women face after birth. Many different factors can contribute to the development of postpartum depression, including perinatal complications, prenatal depression, or social factors. One of the social factors that Black women, specifically, face leading to postpartum depression is discrimination. The purpose of this literature review is to identify research that focuses on whether implicit bias and discrimination by healthcare providers contributes to postpartum depression among Black women. A literature review was conducted using databases including CINHAL Plus Text, CINHAL ULTIMATE, Medline, and APA Psycinfo, with terms that included “healthcare provider* …

Exploring Patient-Provider Communication In Indian American Populations: A Scoping Review, Pranav S. Nadella

Honors Undergraduate Theses

Effective provider-patient communication directly influences patient satisfaction, treatment adherence, and health outcomes, yet the unique experiences of Indian Americans—one of the fastest-growing U.S. populations—remain underexplored in communication research. This scoping review, following Joanna Briggs Institute guidelines, systematically mapped the existing literature on provider-patient communication involving Indian Americans. Eleven studies met inclusion criteria, with data extracted on methods, populations, and seven coded aspects related to communication.

Findings revealed a narrow focus on first-generation immigrants and women, leaving men’s experiences and second-generation voices largely unexamined. Communication was shaped by language discordance, cultural stigma, family involvement, trust dynamics, and health literacy. No studies …

Cognitive Impairment And Depression In Hispanic And Non-Hispanic White Low-Income Older Adults A Cross-Sectional Study, Cecil Latta

Honors Undergraduate Theses

Hispanic older adults represent a growing population in the United States and may be disproportionately affected by cognitive impairment and depression. We theorize that cognitive impairment would be more prevalent in the older Hispanic community and would affect the levels of depression in both Hispanic and non-Hispanic Whites older adults. This cross-sectional study examined the association between cognitive impairment and depression in 157 older adults, including Hispanic (n = 91, 57.96%, age: M = 76.4, SD = 6.8) and non-Hispanic White (n = 66, 42.04%, age: M = 76.2, SD = 6.5). We used the Memory Impairment Screen to assess …