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A Framework For Workforce Management An Agent Based Simulation Approach, Mario Marin Jan 2014

A Framework For Workforce Management An Agent Based Simulation Approach, Mario Marin

Electronic Theses and Dissertations

In today's advanced technology world, enterprises are in a constant state of competition. As the intensity of competition increases the need to continuously improve organizational performance has never been greater. Managers at all levels must be on a constant quest for finding ways to maximize their enterprises' strategic resources. Enterprises can develop sustained competitiveness only if their activities create value in unique ways. There should be an emphasis to transfer this competitiveness to the resources it has on hand and the resources it can develop to be used in this environment. The significance of human capital is even greater now, …


Statistical Analysis Of Depression And Social Support Change In Arab Immigrant Women In Usa, Hazhar Blbas Jan 2014

Statistical Analysis Of Depression And Social Support Change In Arab Immigrant Women In Usa, Hazhar Blbas

Electronic Theses and Dissertations

Arab Muslim immigrant women encounter many stressors and are at risk for depression. Social supports from husbands, family and friends are generally considered mitigating resources for depression. However, changes in social support over time and the effects of such supports on depression at a future time period have not been fully addressed in the literature This thesis investigated the relationship between demographic characteristics, changes in social support, and depression in Arab Muslim immigrant women to the USA. A sample of 454 married Arab Muslim immigrant women provided demographic data, scores on social support variables and depression at three time periods …


The Impact Of A Group Counseling Intervention On Lesbian, Gay, Bisexual, Transgender, And Queer Older Adolescents' Levels Of Hope, Coping, And Suicidality, Catherine Lamb Jan 2014

The Impact Of A Group Counseling Intervention On Lesbian, Gay, Bisexual, Transgender, And Queer Older Adolescents' Levels Of Hope, Coping, And Suicidality, Catherine Lamb

Electronic Theses and Dissertations

This investigation examined the impact of an eight-week group counseling intervention on lesbian, gay, bisexual, transgender, and queer (LGBTQ+) older adolescents’ (aged 18-20) levels of hopefulness, coping skills, and suicidality. An experimental, randomized-controlledtrial research design was employed to identify differences between the intervention group and waitlist control group participants’ hopefulness, coping skills, and suicidality scores. In addition, the relationship between the LGBTQ+ participants’ outcome variables (hopefulness, coping skills, and suicidality) scores was examined. Furthermore, the impact of group therapeutic factors experienced by the LGBTQ+ participants in intervention group for the variables of hopefulness, coping skills, and suicidality was examined. Key …


The Subject Librarian Newsletter, Philosophy, Spring 2014, Richard Harrison Jan 2014

The Subject Librarian Newsletter, Philosophy, Spring 2014, Richard Harrison

Libraries' Newsletters

No abstract provided.


The Subject Librarian Newsletter, Sports Business Management, Spring 2014, Missy Murphey Jan 2014

The Subject Librarian Newsletter, Sports Business Management, Spring 2014, Missy Murphey

Libraries' Newsletters

No abstract provided.


Melatonin-Induced Temporal Up-Regulation Of Gene Expression Related To Ubiquitin/Proteasome System (Ups) In The Human Malaria Parasite Plasmodium Falciparum, Fernando C. Koyama, Mauro F. Azevedo, Alexandre Budu, Debopam Chakrabarti, Célia R. S. Garcia Jan 2014

Melatonin-Induced Temporal Up-Regulation Of Gene Expression Related To Ubiquitin/Proteasome System (Ups) In The Human Malaria Parasite Plasmodium Falciparum, Fernando C. Koyama, Mauro F. Azevedo, Alexandre Budu, Debopam Chakrabarti, Célia R. S. Garcia

Faculty Bibliography 2010s

There is an increasing understanding that melatonin and the ubiquitin/ proteasome system (UPS) interact to regulate multiple cellular functions. Post-translational modifications such as ubiquitination are important modulators of signaling processes, cell cycle and many other cellular functions. Previously, we reported a melatonin-induced upregulation of gene expression related to ubiquitin/proteasome system (UPS) in Plasmodium falciparum, the human malaria parasite, and that P. falciparum protein kinase 7 influences this process. This implies a role of melatonin, an indolamine, in modulating intraerythrocytic development of the parasite. In this report we demonstrate by qPCR analysis, that melatonin induces gene upregulation in nine out of …


A Unified Framework For Individualized Avatar-Based Interactions, Arjun Nagendran, Remo Pillat, Adam Kavanaugh, Greg Welch, Charles Hughes Jan 2014

A Unified Framework For Individualized Avatar-Based Interactions, Arjun Nagendran, Remo Pillat, Adam Kavanaugh, Greg Welch, Charles Hughes

Faculty Bibliography 2010s

This paper presents a framework to interactively control avatars in remote environments. The system, called AMITIES,. serves as the central component that connects people controlling avatars (inhabiters), various manifestation's of these avatars (surrogates), and people interacting with these avatars (participants). A multiserver client architecture, based on a low-demand network protocol, connects the participant environment(s), the inhabiter station(s), and the avatars. A human-in-the-loop metaphor provides an interface for remote operation, with support for multiple inhabiters, multiple avatars, and multiple participants. Custom animation blending routines and a gesture-based interface provide inhabiters with an intuitive avatar control paradigm. This gesture control is enhanced …


The Effect Of Normally Consumed Amounts Of Sucrose Or High Fructose Corn Syrup On Lipid Profiles, Body Composition And Related Parameters In Overweight/Obese Subjects, Joshua Lowndes, Stephanie Sinnett, Sabrina Pardo, Von T. Nguyen, Kathleen J. Melanson, Zhiping Yu, Britte E. Lowther, James M. Rippe Jan 2014

The Effect Of Normally Consumed Amounts Of Sucrose Or High Fructose Corn Syrup On Lipid Profiles, Body Composition And Related Parameters In Overweight/Obese Subjects, Joshua Lowndes, Stephanie Sinnett, Sabrina Pardo, Von T. Nguyen, Kathleen J. Melanson, Zhiping Yu, Britte E. Lowther, James M. Rippe

Faculty Bibliography 2010s

The American Heart Association (AHA) has advocated that women and men not consume more than 100 and 150 kcal/day, respectively, from added sugars. These levels are currently exceeded by over 90% of the adult population in the United States. Few data exist on longer-term metabolic effects when sucrose and High Fructose Corn Syrup (HFCS), the principal sources of added dietary sugars, are consumed at levels typical of the general population. Sixty five overweight and obese individuals were placed on a eucaloric (weight stable) diet for 10-weeks, which incorporated sucrose- or HFCS-sweetened, low-fat milk at 10% or 20% of calories in …


The Effects Of Fructose-Containing Sugars On Weight, Body Composition And Cardiometabolic Risk Factors When Consumed At Up To The 90th Percentile Population Consumption Level For Fructose, Joshua Lowndes, Stephanie Sinnett, Zhiping Yu, James Rippe Jan 2014

The Effects Of Fructose-Containing Sugars On Weight, Body Composition And Cardiometabolic Risk Factors When Consumed At Up To The 90th Percentile Population Consumption Level For Fructose, Joshua Lowndes, Stephanie Sinnett, Zhiping Yu, James Rippe

Faculty Bibliography 2010s

The American Heart Association (AHA) and World Health Organization (WHO) have recommended restricting calories from added sugars at lower levels than the Institute of Medicine (IOM) recommendations, which are incorporated in the Dietary Guidelines for Americans 2010 (DGAs 2010). Sucrose (SUC) and high fructose corn syrup (HFCS) have been singled out for particular concern, because of their fructose content, which has been specifically implicated for its atherogenic potential and possible role in elevating blood pressure through uric acid-mediated endothelial dysfunction. This study explored the effects when these sugars are consumed at typical population levels up to the 90th percentile population …


Behavior Change Techniques Implemented In Electronic Lifestyle Activity Monitors: A Systematic Content Analysis, Elizabeth J. Lyons, Zakkiyya H. Lewis, Brian G. Mayrsohn, Jennifer L. Rowland Jan 2014

Behavior Change Techniques Implemented In Electronic Lifestyle Activity Monitors: A Systematic Content Analysis, Elizabeth J. Lyons, Zakkiyya H. Lewis, Brian G. Mayrsohn, Jennifer L. Rowland

Faculty Bibliography 2010s

Background: Electronic activity monitors (such as those manufactured by Fitbit, Jawbone, and Nike) improve on standard pedometers by providing automated feedback and interactive behavior change tools via mobile device or personal computer. These monitors are commercially popular and show promise for use in public health interventions. However, little is known about the content of their feedback applications and how individual monitors may differ from one another. Objective: The purpose of this study was to describe the behavior change techniques implemented in commercially available electronic activity monitors. Methods: Electronic activity monitors (N=13) were systematically identified and tested by 3 trained coders …


The Impact Of Social Context On Learning And Cognitive Demands For Interactive Virtual Human Simulations, Rebecca Lyons, Teresa R. Johnson, Mohammed K. Khalil, Juan C. Cendàn Jan 2014

The Impact Of Social Context On Learning And Cognitive Demands For Interactive Virtual Human Simulations, Rebecca Lyons, Teresa R. Johnson, Mohammed K. Khalil, Juan C. Cendàn

Faculty Bibliography 2010s

Interactive virtual human (IVH) simulations offer a novel method for training skills involving person-to-person interactions. This article examines the effectiveness of an IVH simulation for teaching medical students to assess rare cranial nerve abnormalities in both individual and small-group learning contexts. Individual (n = 26) and small-group (n = 30) interaction with the IVH system was manipulated to examine the influence on learning, learner engagement, perceived cognitive demands of the learning task, and instructional efficiency. Results suggested the IVH activity was an equally effective and engaging instructional tool in both learning structures, despite learners in the group learning contexts having …


Tcr Triggering By Pmhc Ligands Tethered On Surfaces Via Poly(Ethylene Glycol) Depends On Polymer Length, Zhengyu Ma, David N. Lebard, Sharon M. Loverde, Kim A. Sharp, Michael L. Klein, Dennis E. Discher, Terri H. Finkel Jan 2014

Tcr Triggering By Pmhc Ligands Tethered On Surfaces Via Poly(Ethylene Glycol) Depends On Polymer Length, Zhengyu Ma, David N. Lebard, Sharon M. Loverde, Kim A. Sharp, Michael L. Klein, Dennis E. Discher, Terri H. Finkel

Faculty Bibliography 2010s

Antigen recognition by T cells relies on the interaction between T cell receptor (TCR) and peptide-major histocompatibility complex (pMHC) at the interface between the T cell and the antigen presenting cell (APC). The pMHC-TCR interaction is two-dimensional (2D), in that both the ligand and receptor are membrane-anchored and their movement is limited to 2D diffusion. The 2D nature of the interaction is critical for the ability of pMHC ligands to trigger TCR. The exact properties of the 2D pMHC-TCR interaction that enable TCR triggering, however, are not fully understood. Here, we altered the 2D pMHC-TCR interaction by tethering pMHC ligands …


A New Framework For Resolving Conflicts Over Transboundary Rivers Using Bankruptcy Methods, K. Madani, M. Zarezadeh, S. Morid Jan 2014

A New Framework For Resolving Conflicts Over Transboundary Rivers Using Bankruptcy Methods, K. Madani, M. Zarezadeh, S. Morid

Faculty Bibliography 2010s

A novel bankruptcy approach is proposed for resolving transboundary river conflicts in which the total water demand or claim of the riparian parties is more than the available water. Bankruptcy solution methods can allocate the available water to the conflicting parties with respect to their claims. Four commonly used bankruptcy methods in the economic literature are used here to develop new river bankruptcy solution methods for allocating water to the riparian parties of river systems. Given the non-uniform spatial and temporal distribution of water across river basins, the proposed solution methods are formulated as non-linear network flow optimization models to …


Influence Of Gender And Muscle Architecture Asymmetry On Jump And Sprint Performance, Gerald T. Mangine, David H. Fukuda, Michael B. Lamonica, Adam M. Gonzalez, Adam J. Wells, Jeremy R. Townsend, Adam R. Jajtner, Maren S. Fragala, Jeffrey R. Stout, Jay R. Hoffman Jan 2014

Influence Of Gender And Muscle Architecture Asymmetry On Jump And Sprint Performance, Gerald T. Mangine, David H. Fukuda, Michael B. Lamonica, Adam M. Gonzalez, Adam J. Wells, Jeremy R. Townsend, Adam R. Jajtner, Maren S. Fragala, Jeffrey R. Stout, Jay R. Hoffman

Faculty Bibliography 2010s

Muscle architecture is a determinant for sprinting speed and jumping power, which may be related to anaerobic sports performance. In the present investigation, the relationships between peak (PVJP) and mean (MVJP) vertical jump power, 30m maximal sprinting speed (30M), and muscle architecture were examined in 28 college-aged, recreationally-active men (n = 14; 24.3 +/- 2.2y; 89.1 +/- 9.3kg; 1.80 +/- 0.07 m) and women (n = 14; 21.5 +/- 1.7y; 65.2 +/- 12.4kg; 1.63 +/- 0.08 m). Ultrasound measures of muscle thickness (MT), pennation angle (PNG), cross-sectional area (CSA), and echo intensity (ECHO) were collected from the rectus femoris (RF) …


The Contribution Of Visceral Fat To Improved Insulin Signaling In Ames Dwarf Mice, Vinal Menon, Xu Zhi, Tanvir Hossain, Andrzej Bartke, Adam Spong, Adam Gesing, Michal M. Masternak Jan 2014

The Contribution Of Visceral Fat To Improved Insulin Signaling In Ames Dwarf Mice, Vinal Menon, Xu Zhi, Tanvir Hossain, Andrzej Bartke, Adam Spong, Adam Gesing, Michal M. Masternak

Faculty Bibliography 2010s

Ames dwarf (Prop1df, df/df) mice are characterized by growth hormone (GH), prolactin, and thyrotropin deficiency, remarkable extension of longevity and increased insulin sensitivity with low levels of fasting insulin and glucose. Plasma levels of anti-inflammatory adiponectin are increased in df/df mice, while pro-inflammatory IL-6 is decreased in plasma and epididymal fat. This represents an important shift in the balance between pro- and anti-inflammatory adipokines in adipose tissue, which was not exposed to GH signals during development or adult life. To determine the role of adipose tissue in the control of insulin signaling in these long-living mutants, we examined the effects …


Notch-1 Mediated Cardiac Protection Following Embryonic And Induced Pluripotent Stem Cell Transplantation In Doxorubicin-Induced Heart Failure, Hilda Merino, Dinender K. Singla Jan 2014

Notch-1 Mediated Cardiac Protection Following Embryonic And Induced Pluripotent Stem Cell Transplantation In Doxorubicin-Induced Heart Failure, Hilda Merino, Dinender K. Singla

Faculty Bibliography 2010s

Doxorubicin (DOX), an effective chemotherapeutic drug used in the treatment of various cancers, is limited in its clinical applications due to cardiotoxicity. Recent studies suggest that transplanted adult stem cells inhibit DOX-induced cardiotoxicity. However, the effects of transplanted embryonic stem (ES) and induced pluripotent stem (iPS) cells are completely unknown in DOX-induced left ventricular dysfunction following myocardial infarction (MI). In brief, C57BL/6 mice were divided into five groups: Sham, DOX-MI, DOX-MI+ cell culture (CC) media, DOX-MI+ ES cells, and DOX-MI+ iPS cells. Mice were injected with cumulative dose of 12 mg/kg of DOX and 2 weeks later, MI was induced …


Mycobacterium Avium Subspecies Paratuberculosis Causes Crohn's Disease In Some Inflammatory Bowel Disease Patients, Saleh A. Naser, Sudesh R. Sagramsingh,, Abed S. Naser, Saisathya Thanigachalam Jan 2014

Mycobacterium Avium Subspecies Paratuberculosis Causes Crohn's Disease In Some Inflammatory Bowel Disease Patients, Saleh A. Naser, Sudesh R. Sagramsingh,, Abed S. Naser, Saisathya Thanigachalam

Faculty Bibliography 2010s

Crohn's disease (CD) is a chronic inflammatory condition that plagues millions all over the world. This debilitating bowel disease can start in early childhood and continue into late adulthood. Signs and symptoms are usually many and multiple tests are often required for the diagnosis and confirmation of this disease. However, little is still understood about the cause(s) of CD. As a result, several theories have been proposed over the years. One theory in particular is that Mycobacterium avium subspecies paratuberculosis (MAP) is intimately linked to the etiology of CD. This fastidious bacterium also known to cause Johne's disease in cattle …


Do Changes In Muscle Architecture Affect Post-Activation Potentiation?, Danielle Reardon, Jay R. Hoffman, Gerald T. Mangine, Adam J. Wells, Adam M. Gonzalez, Adam R. Jajtner, Jeremy R. Townsend, William P. Mccormack, Jeffrey R. Stout, Maren S. Fragala, David H. Fukuda Jan 2014

Do Changes In Muscle Architecture Affect Post-Activation Potentiation?, Danielle Reardon, Jay R. Hoffman, Gerald T. Mangine, Adam J. Wells, Adam M. Gonzalez, Adam R. Jajtner, Jeremy R. Townsend, William P. Mccormack, Jeffrey R. Stout, Maren S. Fragala, David H. Fukuda

Faculty Bibliography 2010s

The purpose of this randomized, cross-over design study was to examine the effect of three different muscle potentiation protocols on acute changes in muscle architecture and vertical jump performance. Eleven experienced, resistance trained men (25.2 +/- 3.6y) completed three potentiation squat protocols using moderate intensity (MI; 75%, 3 sets x 10 repetitions), high intensity (HI; 90%, 3 sets x 3 repetitions) and 100% (1RM; 1 set x 1repetition) of their 1RM. In addition, all participants completed a control session (CTL) in which no protocol was performed. During each testing session, muscle architecture and vertical jump testing were assessed at baseline …


"Lapbotic" Surgery: Blending The Expertise Of An Advanced Minimally Invasive Surgeon With The Precision Of A Robot To Best Serve The Patient, Jay A. Redan Jan 2014

"Lapbotic" Surgery: Blending The Expertise Of An Advanced Minimally Invasive Surgeon With The Precision Of A Robot To Best Serve The Patient, Jay A. Redan

Faculty Bibliography 2010s

No abstract provided.


High-Intensity Interval Training And Beta-Hydroxy-Beta-Methylbutyric Free Acid Improves Aerobic Power And Metabolic Thresholds, Edward H. Robinson Iv, Jeffrey R. Stout, Amelia A. Miramonti, David H. Fukuda, Ran Wang, Jeremy R. Townsend, Gerald T. Mangine, Maren S. Fragala, Jay R. Hoffman Jan 2014

High-Intensity Interval Training And Beta-Hydroxy-Beta-Methylbutyric Free Acid Improves Aerobic Power And Metabolic Thresholds, Edward H. Robinson Iv, Jeffrey R. Stout, Amelia A. Miramonti, David H. Fukuda, Ran Wang, Jeremy R. Townsend, Gerald T. Mangine, Maren S. Fragala, Jay R. Hoffman

Faculty Bibliography 2010s

Background: Previous research combining Calcium beta-hydroxy-beta-methylbutyrate (CaHMB) and running high-intensity interval training (HIIT) have shown positive effects on aerobic performance measures. The purpose of this study was to examine the effect of beta-hydroxy-beta-methylbutyric free acid (HMBFA) and cycle ergometry HIIT on maximal oxygen consumption (VO(2)peak), ventilatory threshold (VT), respiratory compensation point (RCP) and time to exhaustion (T-max) in college-aged men and women. Methods: Thirty-four healthy men and women (Age: 22.7 +/- 3.1 yrs; VO(2)peak: 39.3 +/- 5.0 ml center dot kg(-1)center dot min(-1)) volunteered to participate in this double-blind, placebo-controlled design study. All participants completed a series of tests prior …


Pathophysiology Of Autism Spectrum Disorders: Revisiting Gastrointestinal Involvement And Immune Imbalance, Mohtashem Samsam, Raheleh Ahangari, Saleh A. Naser Jan 2014

Pathophysiology Of Autism Spectrum Disorders: Revisiting Gastrointestinal Involvement And Immune Imbalance, Mohtashem Samsam, Raheleh Ahangari, Saleh A. Naser

Faculty Bibliography 2010s

Autism spectrum disorders (ASD) comprise a group of neurodevelopmental abnormalities that begin in early childhood and are characterized by impairment of social communication and behavioral problems including restricted interests and repetitive behaviors. Several genes have been implicated in the pathogenesis of ASD, most of them are involved in neuronal synaptogenesis. A number of environmental factors and associated conditions such as gastrointestinal (GI) abnormalities and immune imbalance have been linked to the pathophysiology of ASD. According to the March 2012 report released by United States Centers for Disease Control and Prevention, the prevalence of ASD has sharply increased during the recent …


Toward In Vitro Models Of Brain Structure And Function, Michael L. Shuler, James J. Hickman Jan 2014

Toward In Vitro Models Of Brain Structure And Function, Michael L. Shuler, James J. Hickman

Faculty Bibliography 2010s

No abstract provided.


Utilization Of Microscale Silicon Cantilevers To Assess Cellular Contractile Function In Vitro, Alec S. T. Smith, Christopher J. Long, Christopher Mcaleer, Nathaniel Bobbitt, Balaji Srinivasan, James J. Hickman Jan 2014

Utilization Of Microscale Silicon Cantilevers To Assess Cellular Contractile Function In Vitro, Alec S. T. Smith, Christopher J. Long, Christopher Mcaleer, Nathaniel Bobbitt, Balaji Srinivasan, James J. Hickman

Faculty Bibliography 2010s

The development of more predictive and biologically relevant in vitro assays is predicated on the advancement of versatile cell culture systems which facilitate the functional assessment of the seeded cells. To that end, microscale cantilever technology offers a platform with which to measure the contractile functionality of a range of cell types, including skeletal, cardiac, and smooth muscle cells, through assessment of contraction induced substrate bending. Application of multiplexed cantilever arrays provides the means to develop moderate to high-throughput protocols for assessing drug efficacy and toxicity, disease phenotype and progression, as well as neuromuscular and other cell-cell interactions. This manuscript …


Death And Disability In A Younge Phase Community, Michael W. Spence, Lana J. Williams, Sandra M. Wheeler Jan 2014

Death And Disability In A Younge Phase Community, Michael W. Spence, Lana J. Williams, Sandra M. Wheeler

Faculty Bibliography 2010s

Roffelsen is an early Younge phase mortuary component in southwestern Ontario. The single burial feature is a pit containing the articulated skeletons of seven successively buried individuals, ranging in age from a few months to late middle age. All had been stripped of soft tissues, except for the connecting tissues that maintained their articulation. Most also had a disk cut from the cranium and a hole drilled near bregma. All but the Want display various forms of developmental failure of the outer and middle ear and the petrous portion of the temporal bone. The pit was apparently the burial facility …


Growth Hormone Action Predicts Age-Related White Adipose Tissue Dysfunction And Senescent Cell Burden In Mice, Michael B. Stout, Tamara Tchkonia, Tamar Pirtskhalava, Allyson K. Palmer, Edward O. List, Darlene E. Berryman, Ellen R. Lubbers, Carlos Escande, Adam Spong, Michal M. Masternak, Ann L. Oberg, Nathan K. Lebrasseur, Richard A. Miller, John J. Kopchick, Andrzej Bartke, James L. Kirkland Jan 2014

Growth Hormone Action Predicts Age-Related White Adipose Tissue Dysfunction And Senescent Cell Burden In Mice, Michael B. Stout, Tamara Tchkonia, Tamar Pirtskhalava, Allyson K. Palmer, Edward O. List, Darlene E. Berryman, Ellen R. Lubbers, Carlos Escande, Adam Spong, Michal M. Masternak, Ann L. Oberg, Nathan K. Lebrasseur, Richard A. Miller, John J. Kopchick, Andrzej Bartke, James L. Kirkland

Faculty Bibliography 2010s

The aging process is associated with the development of several chronic diseases. White adipose tissue (WAT) may play a central role in age-related disease onset and progression due to declines in adipogenesis with advancing age. Recent reports indicate that the accumulation of senescent progenitor cells may be involved in age-related WAT dysfunction. Growth hormone (GH) action has profound effects on adiposity and metabolism and is known to influence lifespan. In the present study we tested the hypothesis that GH activity would predict age-related WAT dysfunction and accumulation of senescent cells. We found that long-lived GH-deficient and -resistant mice have reduced …


Toll Mediated Infection Response Is Altered By Gravity And Spaceflight In Drosophila, Katherine Taylor, Kurt Kleinhesselink, Michael D. George, Rachel Morgan, Tangi Smallwood, Ann S. Hammonds, Patrick M. Fuller, Perot Saelao, Jeff Alley, Allen G. Gibbs, Deborah K. Hoshizaki, Laurence Von Kalm, Charles A. Fuller, Kathleen M. Beckingham, Deborah A. Kimbrell Jan 2014

Toll Mediated Infection Response Is Altered By Gravity And Spaceflight In Drosophila, Katherine Taylor, Kurt Kleinhesselink, Michael D. George, Rachel Morgan, Tangi Smallwood, Ann S. Hammonds, Patrick M. Fuller, Perot Saelao, Jeff Alley, Allen G. Gibbs, Deborah K. Hoshizaki, Laurence Von Kalm, Charles A. Fuller, Kathleen M. Beckingham, Deborah A. Kimbrell

Faculty Bibliography 2010s

Space travel presents unlimited opportunities for exploration and discovery, but requires better understanding of the biological consequences of long-term exposure to spaceflight. Immune function in particular is relevant for space travel. Human immune responses are weakened in space, with increased vulnerability to opportunistic infections and immune-related conditions. In addition, microorganisms can become more virulent in space, causing further challenges to health. To understand these issues better and to contribute to design of effective countermeasures, we used the Drosophila model of innate immunity to study immune responses in both hypergravity and spaceflight. Focusing on infections mediated through the conserved Toll and …


The Potential Impact Of Expanding Target Age Groups For Polio Immunization Campaigns, Radboud J. Duintjer Tebbens, Dominika A. Kalkowska, Steven G. F. Wassilak, Mark A. Pallansch, Stephen L. Cochi, Kimberly M. Thompson Jan 2014

The Potential Impact Of Expanding Target Age Groups For Polio Immunization Campaigns, Radboud J. Duintjer Tebbens, Dominika A. Kalkowska, Steven G. F. Wassilak, Mark A. Pallansch, Stephen L. Cochi, Kimberly M. Thompson

Faculty Bibliography 2010s

Background: Global efforts to eradicate wild polioviruses (WPVs) continue to face challenges due to uninterrupted endemic WPV transmission in three countries and importation-related outbreaks into previously polio-free countries. We explore the potential role of including older children and adults in supplemental immunization activities (SIAs) to more rapidly increase population immunity and prevent or stop transmission. Methods: We use a differential equation-based dynamic poliovirus transmission model to analyze the epidemiological impact and vaccine resource implications of expanding target age groups in SIAs. We explore the use of older age groups in SIAs for three situations: alternative responses to the 2010 outbreak …


A New Crash Test: The Rise And Fall Of Florida Motor Vehicle No-Fault Law, James Colquitt Jan 2014

A New Crash Test: The Rise And Fall Of Florida Motor Vehicle No-Fault Law, James Colquitt

HIM 1990-2015

Florida is one of 12 states that have a no-fault law. The first party benefit coverage is known as personal injury protection (PIP). Every policy sold in the state must include at least $10,000 in personal injury protection. This law went into effect in 1971 and is now being challenged. Changes in consumer, lawyer, and doctor behavior as well as changes in the legal and economic environment have diminished the positive impact of the no-fault law. This thesis will focus on the diminished effectiveness of the no-fault law in Florida. It will be based on research from primary sources. Other …


The Use Of Physical Restraints Among Nursing Home Residents: Do Disparities Exist?, Shekinah Fashaw Jan 2014

The Use Of Physical Restraints Among Nursing Home Residents: Do Disparities Exist?, Shekinah Fashaw

HIM 1990-2015

Introduction: The purpose of this study is to examine how nursing home (NH) characteristics, specifically racial composition of nursing homes residents, influences the use of physical restraints. As the population ages and becomes more diverse, it is essential to mitigate/eliminate racial/ethnic disparities in quality care. Methods: This is cross-sectional study using a 2010 national data set from Brown University Center for Gerontology and Healthcare Research. This study employs Donabedian's Structure-Process-Outcome (SPO) conceptual framework. Statistical analysis includes univariate, bivariate, and a logistic regression model. It is hypothesized that nursing homes with higher proportions of black residents, more Medicaid residents, and for-profit …


Exploring The Relationships Among Personality Traits And Nontechnical Skills In College Students, John Doyle Jan 2014

Exploring The Relationships Among Personality Traits And Nontechnical Skills In College Students, John Doyle

HIM 1990-2015

Previous research established that traditional indicators of academic achievement, such as GPA, serve as insufficient predictors of success outside the academic environment. Employers find many graduates ill-prepared for the expectations of the corporate world because they lack skills such as creativity and critical thinking. The present study explores the relationship among personality, creativity, and critical thinking. Identifying personality traits that correlate with the presence of creativity and critical thinking may help employers identify job candidates who possess these much desired skills. In this study, 97 participants completed the NEO PI-R as a measure of personality, the Cornel Critical Thinking Test, …