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Malondialdehyde (Mda) And Glutathione Peroxidase (Gpx) Are Elevated In Crohns Disease-Associated With Mycobacterium Avium Subspecies Paratuberculosis (Map), Ahmad Qasem

Electronic Theses and Dissertations

Inflamed tissue in Crohn’s disease (CD) are continuously producing toxic oxygen metabolites leading to cellular injury and apoptosis. Here, we are evaluating the role of Mycobacterium avium subspecies paratuberculosis (MAP) in oxidative stress in CD by evaluation of lipid peroxidation and antioxidant defense activity. Specifically, we measured malondialdehyde (MDA) level and selenium-dependent glutathione peroxidase (GPx) activity in the plasma from patients and cattle infected with MAP. The level of MAP antibodies in bovine sera was determined by IDEXX kit whereas detection of MAP DNA was performed by IS900-based nPCR. A total of 42 cattle (21 infected with MAP and 21 …

Structural And Functional Characterization Of Enzymes Of A Novel Group Of Tryptophylquinone Cofactor Containing Oxidases, Esha Sehanobish

Electronic Theses and Dissertations

Protein-derived cofactors are redox and catalytic centers that are generally formed by the posttranslational modifications of one or more amino acids. An important class of these cofactors are the quinones derived from tyrosine and tryptophan. Amongst redox proteins, it has been known till now that oxidases either contain a flavin or a tyrosylquinone cofactor, whereas tryptophylquinone ones are present within the dehydrogenases. In recent times, oxidases from a marine bacterium, Marinomonas mediterranea, have been shown to possess the latter. This study involves the characterization of two such proteins, lysine-?-oxidase (LodA) and glycine oxidase (GoxA). They have been reported to contain …

A Hybrid Simulation Framework Of Consumer-To-Consumer Ecommerce Space, Oloruntomi Joledo

Electronic Theses and Dissertations

In the past decade, ecommerce transformed the business models of many organizations. Information Technology leveled the playing field for new participants, who were capable of causing disruptive changes in every industry. "Web 2.0" or "Social Web" further redefined ways users enlist for services. It is now easy to be influenced to make choices of services based on recommendations of friends and popularity amongst peers. This research proposes a simulation framework to investigate how actions of stakeholders at this level of complexity affect system performance as well as the dynamics that exist between different models using concepts from the fields of …

Dynamic Modeling Approach To Quantify Change Orders Impact On Labor Productivity, Zain Al-Kofahi

Electronic Theses and Dissertations

In construction projects, change orders are commonly faced. These change orders, which are issued by the owner, may cause interruption to the contractor's work, resulting in damages such as loss of labor productivity, delay damages, and cost overruns which may lead to claims. The relationship between change orders and loss of labor productivity is not well understood because of the difficulty in linking the cause of the productivity loss to the change order. So, to receive compensation, the contractor needs to prove with a credible calculation that the productivity loss was a result of the change order issued by the …

Informational Efficiency And The Reaction To Terrorism: A Financial Perspective, Nicholas Roland

Honors Undergraduate Theses

The purpose of this study is to measure the message terror organizations hope to convey using the financial markets as a proxy of measurement to determine patterns within the marketplace and the effects on the terrorists’ ability to deliver a desired message due to the increased use of digital devices and access to instantaneous news, seen over the past decade. Using death count, geographic location, and event type, this study identified 109 attacks between 1985 and 2015 to be analyzed against 5 market indices and 5 securities. Measuring the effects within a 10-day sample window from the time of the …

Adolescent Mothers’ Implementation Of Strategies To Enhance Their Children’S Early Language And Emergent Literacy Skills, Meredith C. Canty

Honors Undergraduate Theses

Previous studies have examined how the language skills of children with adolescent mothers differs from children of older mothers. However, there is limited information on what specific strategies adolescent mothers utilize to increase early language and emergent literacy skills in their children. The aim of the present study is to examine adolescent mothers’ use of strategies to increase the early language and emergent literacy skills of their young children. A sample of 14 adolescent mothers enrolled in a teen parenting program were surveyed on their use of common strategies that are shown to facilitate early development of language and literacy …

A Survey Of Preservice Teachers' Attitudes On Integrating Students With Disabilities In Inclusive Education Classrooms, Kelsey K. Mcnamee

Honors Undergraduate Theses

There are more than 2.4 million American public school students identified with learning disabilities who are served under the Individuals with Disabilities Education Act (IDEA). General education preservice teachers are expected to effectively teach all students, including those with disabilities. However, most teacher preparation programs only require a single course in teaching students with disabilities. Research shows that that teachers’ attitudes regarding inclusion are the greatest predictor of a successful inclusion classroom. This study explored the attitudes of preservice elementary and preservice secondary teachers regarding integrating students with disabilities into general education classrooms. A quantitative research design with a survey …

Pharmacogenomic Management Of Familial Hypercholesterolemia: An Integrative Review Of The Literature, Brian V. Skibo

Honors Undergraduate Theses

The purpose of this thesis is to examine familial hypercholesterolemia (FH) and emerging pharmacogenomics therapies that propose to lower serum low density lipid (LDL) levels. The search of various data bases resulted in nine research articles being selected for review. Syntheses of the articles suggest emerging phamacogenomic drug therapy can improve treatment outcomes for individuals with a diagnosis of FH. The Human Genome Project (HGP) has had far reaching applications for genomic technologies and pharmacagenomic interventions, tailored to human conditions associated with select genomic traits. Synthesis of nine research articles demonstrate that little is known on the topic and reveals …

Nursing Knowledge And Perceived Comfort Level In Acute Infusion Reactions From Antineoplastic Agents, Andrea L. Maiorini

Honors Undergraduate Theses

INTRODUCTION: Acute infusion reactions from antineoplastic agents can include hypersensitivity reactions, anaphylaxis, and cytokine release infusion reactions. Severe acute infusion reactions happen in about 5% of the oncology patient population and nurses are responsible for assessment and management of the reaction. This is a high-stress task for a nurse magnified by the lack of exposure. This project explores nursing knowledge and perceived comfort level of acute infusion reactions caused by antineoplastic agents.

METHODOLOGY: An original survey was created to test nursing knowledge and assess comfort level. Nursing knowledge was broken down into six subscales: general knowledge of acute infusion reactions, …

The Study Of The Adverse Effects Of Childhood Maltreatment, Katie A. Kennie

Honors Undergraduate Theses

This study explores the link between the presence of childhood trauma and adult criminal behavior. In this study, four distinct categories of childhood trauma (physical abuse, sexual abuse, psychological abuse, and neglect) were examined. In addition, this study conducts a comparative analysis of the United States crime rate with that of Switzerland and Japan. This study examines and compares the policies utilized in ensuring the protection of child welfare. The ultimate goal is to provide research which may build a foundation that will assist in creating and improving policies which will ensure a child's psychological health.

Retention Of Cardiopulmonary Resuscitation Knowledge And Psychomotor Skill Among Undergraduate Nursing Students: An Integrative Review Of Literature, Fernanda Tirado

Honors Undergraduate Theses

Purpose: The purpose of this integrative literature review is to explore the effectiveness of different training modalities on the acquisition and retention of CPR knowledge and psychomotor skill among undergraduate nursing students. Background: It is well known that standard CPR-training is ineffective at preparing nurses for the rigors of a cardiac arrest event. Survival rates for in-hospital cardiac arrests remain low and the proportion of neurobehavioral sequelae among survivors is very high. Methods: A review of relevant literature published between 2006 and 2016 was conducted using the CINAHL and MEDLINE databases. The following key terms were used in the search: …

Supervisor Expectations, Event Reporting, And Patient Safety Perceptions: Exploring Potential Moderators And Mediators, Claudia Hernandez

Honors Undergraduate Theses

Given the high number of errors and negative events committed within medical settings, the emphasis on patient safety culture is becoming more prevalent. Despite this effort, underreporting has been and continues to be an issue in this area. Some research has shown a link between underreporting and lack of management responsiveness, but more work is necessary to identify reasons for underreporting and potential mitigating solutions. The objective of the present research is to answer questions regarding the impact supervisors have on staff’s patient safety perceptions and event reporting, through the use of archival survey data collected with the AHRQ Hospital …

Participant's Perception Of Realism And Pediatric Pain Assessment Utilizing A Virtual Patient: A Pilot Study, Alexandra Carson

Honors Undergraduate Theses

The use of simulation in curriculum affords students with the opportunity to enhance clinical skills in a safe environment. However, certain aspects of patient assessment are difficult to reproduce in current simulators, such as changes in facial expressions. Facial expressions are of particular importance when assessing for the presence and severity of pain in the pediatric population. Inconsistencies found in accurate identification of pain suggest the necessity of improved pain assessment training. This study evaluated nursing student’s perceptions of a virtual patient designed to realistically display varying levels of pain in the pediatric patient. Additional purposes of this study were …

Exploring Attachment Behaviors In Urban Mothers And Their Infants, Brooke G. Rusoff

Honors Undergraduate Theses

Infants enter this world relying on caregivers to nurture and protect them. Through this reliance, infants develop an attachment to their caregivers, thus setting the stage for how a child comes to view the world and the people in it. This study sought to further explore attachment behaviors through observation of a voluntary parent education course offered through the Early Learning Coalition of Orange County. Data were collected three times over the course of the nine week program on four mother-infant dyads. Across the three mothers who were present for at least two observations, negative behaviors decreased between the first …

Behavioral Interventions Versus Pharmaceutical Interventions To Reduce Preoperative Anxiety In School Aged Children, Jennifer J. Cline

Honors Undergraduate Theses

Surgical procedures that require general anesthesia can be stressful and create needless anxiety for school-age children. Interventions aimed at reducing preoperative anxiety can improve cooperation and enhance postoperative outcomes by lowering anxiety levels prior to induction of general anesthesia. The purpose of this study was to examine the effects of behavioral interventions versus drug therapy in reducing pre-operative anxiety in children. The secondary purpose was to compare methods used to integrate anxiety reduction interventions into pre-operative care and to evaluate the most widely used and effective strategy for clinical practice. A literature review exploring behavioral based stress reduction interventions and …

Exploring The Art Of Nursing And Its Influence On Patient Satisfaction In Acute Care Settings, Enid Tirado

Honors Undergraduate Theses

‎Nursing is a trusted profession aimed at delivering quality, patient-centered care perceived by patients as caring and satisfactory. While empiric care components are measurable as associated with clinical outcomes, patients’ perceptions of care are increasingly important in determining satisfaction with the patient care experience. Not clearly defined, nor empirically measurable, the “art” of nursing is taking on increasing importance as a component of satisfaction with the patient experience. The purpose of this integrative literature review was to review the literature in order to find common themes influencing determination of the art of nursing on patient satisfaction in acute care settings. …

Intensive Care In Oncology: Admission And Outcomes In Adult Patients With Cancer, Surya John

Honors Undergraduate Theses

Background: Historically, patients with cancer have been perceived as poor candidates for ICU admission. General ICU admission criteria lists cancer patients as low priority in ICU admission depriving them of the care they rightfully deserve. The purpose of this literary synthesis was to examine ICU admission criteria, risk factors, and outcomes of ICU admission in relation to hematological and solid tumor cancers and discuss ways that practitioners and nurses can educate patients with cancer and their families on appropriateness of ICU care.

Methods: A total of 768 articles were found in a literature search including all literature from 2005 to …

The Effect Of Alternative Labor Positions Versus The Lithotomy Position On Birthing Outcomes: An Integrative Literature Review, Kelsey Gaffka

Honors Undergraduate Theses

Traditionally, the lithotomy position is the most commonly used birthing position in western cultures. The purpose of this literature review was to examine the differences in maternal and neonatal outcomes when alternative labor positions are used. Implications for future use of alternative labor positions were explored. Peer reviewed, English-language research articles published from 2009 to 2015 were included for synthesis. Study results revealed that the lithotomy position is linked to multiple negative maternal outcomes. Birthing in a water pool or in a lateral position has been linked to more optimal maternal and neonatal outcomes compared to other positions. Health care …

Identity Development, Social Support, And Motherhood, Dayanara Rosado

Honors Undergraduate Theses

Adolescent pregnancy creates challenges for this minority population in balancing their motherhood identity with continuing to develop their identity at the adolescent stage, which presents a social problem today. The intent of this thesis is to explore the relationship between identity, adjustment, and social support among college students who were adolescent mothers. The following surveys: Personal Network Matrix (PNM), The Identity Distress Scale (IDS), and The Dimension of Identity Development Scale (DIDS), were administered through the UCF SONA system. Participants were divided into three groups: mothers who had their first child as a teenager (teen mothers; n = 6), mothers …

Business Case Studies In Sustainability Practices, Sheri L. Lynch

Honors Undergraduate Theses

Protecting the environment for future generations is crucial. Although businesses are under strong pressure to support sustainability, many leaders find it challenging to meet the environmental needs of the present without negatively impacting their economic goals. This paper describes some methods that businesses have adopted to effectively manage environmental issues and offer an opportunity for competitive advantage. In particular, three case studies show ways that the companies have embraced and integrated sustainability into their strategic planning process, which helped them achieve growth and success in the context of social and environmental concerns. The paper shows how these businesses have chosen …

When People Working In An Office Don't Want To Workout: An Exploration Of Corporate Benefit Use And Correlates To The Big Five Model Of Personality, Dominique T. Harris

Honors Undergraduate Theses

Many corporate offices now offer fitness benefits to their employees. Evidence shows that corporate fitness programs are linked to decreased tardiness, absenteeism, and reduced healthcare costs. These programs also help address the growing obesity crisis threatening one in every three American adults. However, many employees do not participate in corporate fitness plans in spite of the convenience many programs offer. Thus, I wished to explore the personality and lifestyle factors that contribute to older (age 25+) employees’ exercise habits, their use of corporate benefits and correlates to the Big Five model of Personality along with other personality measures. I gathered …

Dosing Accuracy When Administering Oral Medications, Chelsea Hughes

Honors Undergraduate Theses

Inaccurate dosing of children’s liquid medication is a major problem that causes adverse effects for children every year. In order to prevent these errors, education for at risk parents is essential. A survey and observational study was done in order to identify parents/caregivers who make dosing errors when measuring out liquid medication for their children. A total of 25 parents/caregivers with children admitted to Arnold Palmer Hospital were included in this study. Study participants completed a survey that included demographic data as well as parenting experience. The parents were directly observed measuring a dose of corn syrup using Children’s liquid …

Expression Levels Of Virulence Genes In Group A Streptococci: A Response To Aerosolized Propylene Glycol, Michael S. Costello

Honors Undergraduate Theses

Electronic cigarette usage is becoming increasingly prevalent among school age children and young adults. A known bactericidal agent, propylene glycol, is often used as a carrier for nicotine, flavoring, and additional constituents of electronic cigarette juice. This study examined the relationship between propylene glycol and virulence gene expression in Streptococcus pyogenes, a respiratory tract pathogen commonly found in school-age individuals. A variety of virulence genes controlled by the three stand alone regulators mga, RofA, and Rgg/RopB were sampled in an effort to understand the pathway by which virulence is affected. The genes chosen encode C5a peptidase, fibronectin binding protein, hyaluronate …

The United Nations: The Syrian Refugee Crisis, Zahra R. Syed

Honors Undergraduate Theses

The main objective of this research paper is to analyze the international effects the Syrian Conflict has had to the global community. The United Nations High Commissioner for Refugees has declared this conflict to be the worst humanitarian crisis of our time. Millions of Syrians have fled their home country to avoid unjust persecution and are looking to not only neighboring countries, but the European Union for assistance in resettlement.

Since the outbreak of the conflict in Syria in 2011, more than 220,000 people have been massacred, leaving fifty percent of the population in unrest due to home displacement. According …

Forced Motherhood? An Ethnographic Study On State Gender Expectations In Nicaragua, Mikaela M. Mendoza-Cardenal

Honors Undergraduate Theses

The dominant Sandinista party discourse of Nicaragua designates the family as the country’s base social institution, but the prevailing machismo threatens the family’s structure. Men - fathers - leave, either literally as migrant laborers or in the abandonment of their family responsibilities. In order to counteract the men’s socially sanctioned absence, the state deploys a hegemonic expectation of motherhood in the passage of its complete abortion ban, one of the strictest in the world. All forms of abortion, including saving the life of the mother, are banned in Nicaragua and both doctors and women are heavily penalized if an abortion …

Sexual Content In Music's Relationship With Consumers' Body Image, Sexualization And Objectification, Marika Gilbert

Honors Undergraduate Theses

The current study examined the relationship between sexual content in popular pop, rap, and R&B music videos and female consumers’ body image, self-objectification, the objectification of other women, and self-esteem. The current study had two main hypotheses: (1) exposure to sexual content in music videos would be negatively correlated with women’s body image, self-objectification, and the objectification of other women and (2) Women’s body image and self-objectification would mediate the relationship between exposure to sexual content in music videos and self-esteem. Participants included 308 female college students who answered questions related to the study aims online. Exposure to sexual content …

The Second Amendment In The 21st Century: An In-Depth Examination Of Firearm Freedoms And Their Relationship With Public Safety And Interests, Mathew E. Klein

Honors Undergraduate Theses

One of the most hotly contested topics in the world today revolves around an object. An object that has caused debate among all members of society both in the United States, and all across the globe. But how could an object, something that on its own does nothing, spur such heated argument? This object is the evolution of invention and the product of fighting amongst each other. This object changes the way people think and how they act. This object can be used for both good and bad. This object is a gun.

This research project will explore the Second …

The Effect Of Social Media On Sexual Cognitions And Behaviors, Joshua Duarte

Honors Undergraduate Theses

Pop culture and social media have become a prime source of entertainment and communication. The current study focuses on the potential effects of consuming this form of media and how it affects our sexual cognitions and behaviors. A sample of nine hundred and two university students were given self-reporting questionnaires concerning demographics, sexual cognitions, and exposure to sexual content in music. An analysis of music artist’s posts on social media was also performed. It was hypothesized that artists who have sexual content published in their work will also have the same amount of sexual content on social media. However, there …

Exploring Supported Conversation With Familial Caregivers Of Persons With Memory Impairment: A Pilot Study, Arielle Willis

Honors Undergraduate Theses

Teaching conversational strategies has been effective for a wide array of clients with acquired neurologic disorders and their caregivers. Research indicates positive results for Supported Conversation in adults with Aphasia (SCA) secondary to stroke. Applying this method to work with caregivers of persons with memory impairment could prove to be a valid intervention tool. This investigation will examine the applicability of SCA with persons with memory impairment and their familial caregivers. This pilot study is intended to create a conversation regarding SCA and its implementation with persons with memory impairment who still live in the community with their caregivers. Analysis …

The Effect Of Aphasia On Quality Of Life, Coping Style, And Resilience, Nelson J. Hernandez

Honors Undergraduate Theses

Approximately one million people in the United States suffer from aphasia. There are multiple types of aphasia, however they are usually placed into two categories: non-fluent or fluent. The psychosocial factors that are impacted due to the type of aphasia has not been systematically investigated. The purpose of this study is to examine how non-fluent and fluent Individuals With Aphasia (IWA) compare or contrast across three psychosocial factors, Quality of Life (QoL), coping style, and resilience. The World Health Quality of Life- BREF (WHOQOL-BREF), Assimilative-Accommodative Coping Scale (AACS), and the Connor-Davidson Resilience Scale-10 item version (CD-RISC-10), were administered once to …