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Activation And Expansion Of Natural Killer Cells For Cancer Immunotherapy With Ex21 Exosomes, Sara Khederzadeh Jan 2017

Activation And Expansion Of Natural Killer Cells For Cancer Immunotherapy With Ex21 Exosomes, Sara Khederzadeh

Honors Undergraduate Theses

In the field of cancer immunotherapy, NK cells are recognized for their ability to provide a form of innate immunity against tumor cells. However, the average abundance of NK cells in the blood can be as low as 5% of the total lymphocyte population. As a result, it has been a focus to find novel therapies to expand NK cells in vitro while subsequently enhancing the cytotoxicity of these cells. Previously-defined methods include the minimal expansion of NK cells with high levels of cytokines such as IL-2 and IL-15, as well as co-culturing NK cells with feeder cell populations that …

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Examination Of The Rehabilitation Protocol Of Traumatic Transfemoral Amputees And How To Prevent Bone Mineral Density Loss, Emily R. Jenkinson Jan 2017

Examination Of The Rehabilitation Protocol Of Traumatic Transfemoral Amputees And How To Prevent Bone Mineral Density Loss, Emily R. Jenkinson

Honors Undergraduate Theses

The purpose of this literature review was to identify any adaptations that could be made to the rehabilitation process for Traumatic Transfemoral Amputees. Traumatic Transfemoral Amputation is particularly debilitating with the amputees encountering many obstacles throughout the rehabilitation process. These obstacles can prevent the return to pre-morbid functioning. With an ever-increasing number of amputees within the United States, it is imperative the rehabilitation process be addressed. This literature review addresses possible adjustments in the initial stages of rehabilitation examining the post-operative, pre-prosthetic, and prosthetic rehabilitation stage to enhance the physical functioning for the amputee. This comprehensive literature review encompassing 63 …

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What's Black And White And Not Read All Over?: An Examination Of The Evolving Landscape Of Newspapers Through The Lens Of The New York Times, Anne Reiber Jan 2017

What's Black And White And Not Read All Over?: An Examination Of The Evolving Landscape Of Newspapers Through The Lens Of The New York Times, Anne Reiber

Honors Undergraduate Theses

The research and statistics gathered in this thesis begin in 2000. Newspapers began experiencing change due to technology before 2000. However, the information necessary to complete this thesis only goes back to that year. Since the year 2000, the newspaper industry has struggled to adapt to the age of ever-changing technology. Newspapers across the US, including large and well-established publications have been forced to find new strategies that allow them to keep up with new digital technologies. The New York Times was the focus of this study, but it is only one part of a very large industry. However, it …

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Micro-Spectroscopy Of Bio-Assemblies At The Single Cell Level, Jeslin Kera Jan 2017

Micro-Spectroscopy Of Bio-Assemblies At The Single Cell Level, Jeslin Kera

Honors Undergraduate Theses

In this thesis, we investigate biological molecules on a micron scale in the ultraviolet spectral region through the non-destructive confocal absorption microscopy. The setup involves a combination of confocal microscope with a UV light excitation beam to measure the optical absorption spectra with spatial resolution of 1.4 μm in the lateral and 3.6 μm in the axial direction. Confocal absorption microscopy has the benefits of requiring no labels and only low light intensity for excitation while providing a strong signal from the contrast generated by the attenuation of propagating light due to absorption. This enables spatially resolved measurements of single …

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Keep Your Thoughts Off My Body: Social Attitudes Toward Rape-Related Abortions, Ketty Fernandez Jan 2017

Keep Your Thoughts Off My Body: Social Attitudes Toward Rape-Related Abortions, Ketty Fernandez

Electronic Theses and Dissertations

Since the legalization of abortion in 1973, abortion continues to be an ongoing debate among pro-choice and pro-life groups, and politicians, and is one of the many barriers women may face. As rape continues in being a significant social issue, rape-related pregnancies and abortions have been understudied. By using the General Social Survey (GSS), this paper analyzes various sociodemographic variables which may influence social attitudes toward rape-related abortions. Findings indicate that Blacks, women, those living in the South, and age were not significant predictors of whether a pregnant woman should have a legal abortion as a result of rape. Other …

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Dance Students At A Two Year College: Making Sense Of Their Academic, Cultural, And Social World, Benjamin Lopez Jan 2017

Dance Students At A Two Year College: Making Sense Of Their Academic, Cultural, And Social World, Benjamin Lopez

Electronic Theses and Dissertations

The purpose of this dissertation was to investigate the lived experiences of community college dance students. Previous research was examined to provide a more holistic picture of dancers during their college years and while in the workforce. The literature reviewed indicated that the emergence of dance as a field of study was controversial. Its beginnings were marked by debates concerning (a) the very definition of dance as a body of motion and a body of knowledge that includes a history and a philosophy as asserted by Dimondstein (1985), (b) its legitimate place within the academy (the perception that university dance …

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Balancing Multiple Roles: A Re-Examination Of How Work Impacts Academic Performance For Community College Students, Celena Ziems Jan 2017

Balancing Multiple Roles: A Re-Examination Of How Work Impacts Academic Performance For Community College Students, Celena Ziems

Electronic Theses and Dissertations

This study investigated how work impacts academic performance for community college students, from a multiple role balance perspective. Perna (2010) called for a re-examination of the role of work in college students' lives, especially regarding the exploration of benefits, rather than just the detriments of working while studying. According to Karp and Bork (2014), more research was also needed on community college students and how they balance multiple roles. Exploring the relationship between balancing multiple roles and academic performance may provide new insight into how community college students contend with demanding roles, while striving to achieve academic success. This study …

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Assessment Of Physical Workload, Ergonomic Problems And Prevalence Of Pain Among Low Wage Hotel Housekeepers In Orlando, Rachel Mammen Jan 2017

Assessment Of Physical Workload, Ergonomic Problems And Prevalence Of Pain Among Low Wage Hotel Housekeepers In Orlando, Rachel Mammen

Electronic Theses and Dissertations

This research study examined the work conditions, ergonomic problems, and prevalence of pain among low wage hotel room cleaners in Orlando. In most hotels, the cleanliness of guestrooms is one of the most important service standards expected by customers. The role of the housekeeper is thus critical to service provision and hotel profitability. The hospitality industry is a major recruiter of low wage workers with the majority working in housekeeping departments. Due to the nature of the research problem, a positivist quantitative approach was adopted although the survey instrument included space for qualitative comments to some of the latter open-ended …

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Youth Labor Market Conditions And The Neet Population In The Eu: Do Poor Labor Market Opportunities Discourage Youth?, Jennifer Hudson Jan 2017

Youth Labor Market Conditions And The Neet Population In The Eu: Do Poor Labor Market Opportunities Discourage Youth?, Jennifer Hudson

Electronic Theses and Dissertations

This study examines how poor labor market opportunities discourage youth between the ages of 15 and 24 and 15 to 29 from participating in the labor market in the European Union between 2005 and 2013. A critical portion of inactive NEETs (youth not in employment, education, or training) reports to be discouraged due to a recognized "lack of opportunities in the labor market." Despite indications from descriptive analyses that the conditions that drive the distinct subsets of the NEET population vary, empirical examinations of the effects of these conditions on the rates of different NEET groups across countries and over …

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Posttraumatic Stress Disorder Or Combat Experience? A Functional Near-Infrared Spectroscopy Study Of Trauma-Related Auditory And Olfactory Cues, Michael Gramlich Jan 2017

Posttraumatic Stress Disorder Or Combat Experience? A Functional Near-Infrared Spectroscopy Study Of Trauma-Related Auditory And Olfactory Cues, Michael Gramlich

Electronic Theses and Dissertations

While the clinical communities are aware of the prevalence of posttraumatic stress disorder (PTSD) among OEF/OIF/OND veterans, further efforts are necessary to bolster comprehensive strategies for assessment and treatment. The purpose of this study was to investigate whether a combat-related PTSD symptom provocation paradigm would elicit unique neurological responses via functional near-infrared spectroscopy across three groups – combat veterans with PTSD, combat veterans without PTSD, and nonmilitary participants without PTSD. Results indicated that combat veterans with PTSD demonstrated significant activation during exposure to a trauma-related sound compared to nonmilitary personnel at channels 14 (d = 1.03) and 15 (d = …

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Effects Of An Acute High-Volume Isokinetic Intervention On Circulating Levels Of Tnf-Α And Stnfr: Influence Of Age, Eliott Arroyo Delgado Jan 2017

Effects Of An Acute High-Volume Isokinetic Intervention On Circulating Levels Of Tnf-Α And Stnfr: Influence Of Age, Eliott Arroyo Delgado

Electronic Theses and Dissertations

The immune system has been implicated in recovery and muscle regeneration following exercise. In response to muscle damage, the immune system responds with an increase in circulating pro-inflammatory cytokines with the goal of recruiting leukocytes to the damaged area. Tumor Necrosis Factor-alpha (TNF-α), in particular, has been shown to be implicated in both muscle regeneration and muscle wasting. However, it remains unclear whether TNF-α is responsible for the age-related losses in muscle size and function. Also, due to the high clearance rate of TNF-α from circulation, analyzing the circulating levels of soluble TNF-α receptors 1 and 2 (STNFR1 and STNFR2) …

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Effects Of An Acute High-Volume Isokinetic Intervention On Inflammatory And Strength Changes: Influence Of Age, Joseph Gordon Jan 2017

Effects Of An Acute High-Volume Isokinetic Intervention On Inflammatory And Strength Changes: Influence Of Age, Joseph Gordon

Electronic Theses and Dissertations

PURPOSE: The purpose of this study was to compare the effects of a high volume isokinetic intervention on lower body strength and inflammation, as well as markers of muscle damage in the subsequent 48 hours between younger and middle-aged men. METHODS: 19 healthy, recreationally trained men were randomly assigned to two groups, younger adults (YA: 21.8 ± 2.0 y; 90.7 ± 11.6 kg; 21.5 ± 4.1 % body fat), or middle-aged adults (MA: 47.0 ± 4.4 y; 96.0 ± 21.5; 24.8 ± 6.3 % body fat). Both groups reported to the human performance laboratory (HPL) on four separate occasions. On …

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The Influence Of Economics Knowledge On Students' Attitudes Toward Financial Literacy, Lloyd Beckles Jan 2017

The Influence Of Economics Knowledge On Students' Attitudes Toward Financial Literacy, Lloyd Beckles

Electronic Theses and Dissertations

Financial literacy has developed in importance resulting from the growing intricacy of financial markets and the increased responsibility placed on consumers for their own financial security. During last decade, the necessity of financial literacy has been heightened due to increasingly complex products and services. Managing personal finances is important and people must learn to engage in prudent financial decisions required when planning for retirement, education, and home purchases. The ability to understand and manage personal finances is a skill critical to long-term financial security, additionally, there are significant consequences to financial illiteracy that can last for a life-time and many …

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An Anthropological Study Of Eating Perspectives, Meal Composition, And Food Choices Among Diverse Student Populations, Chelsea Daws Jan 2017

An Anthropological Study Of Eating Perspectives, Meal Composition, And Food Choices Among Diverse Student Populations, Chelsea Daws

Electronic Theses and Dissertations

My thesis explores the factors that shape or reinforce international college students' perceptions of food. This research not only examines how cultural values affect individual nutrition and maintenance of eating behaviors, it also addresses the extent to which accessibility impacts eating behaviors. Notably, the research endeavor uses the concept of dietary habitus as an underlying directive mechanism for study. This study finds that most students experience a reduction in their fruit and vegetable intake. Another finding suggests that international students eat healthier and are more structured in comparison to domestic students if they hybridize their dietary habitus. Research findings also …

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Probation Officer Productivity: Using The Effort-Reward Imbalance Model, Brandon Presley Jan 2017

Probation Officer Productivity: Using The Effort-Reward Imbalance Model, Brandon Presley

Electronic Theses and Dissertations

The purpose of this study is to determine the extent to which workplace efforts and rewards are associated with probation officer stress, overcommitment, health, and productivity. This research uses the effort-reward imbalance model, which is an indicator of job stress, on a group of criminal justice probation officers. The probation officers completed questionnaires regarding their perceptions of health, perceived reward, perceived effort, perceptions of overcommitment, and perceived productivity. Afterward, the responses were collected, and analyses were conducted using correlation and multiple regression to determine the extent to which perceptions of effort, reward, and overcommitment effect probation officer productivity and health. …

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The Influences Of Roles And Support Systems On The Baccalaureate Degree Attainment Of Nontraditional Learners, Shirdricka Roberts Jan 2017

The Influences Of Roles And Support Systems On The Baccalaureate Degree Attainment Of Nontraditional Learners, Shirdricka Roberts

Electronic Theses and Dissertations

The purpose of the research study was to examine the influences of roles and support systems on the baccalaureate attainment of nontraditional learners. A qualitative bounded case study was conducted that include ten face-to-face interviews with nontraditional learners attending the same University during the same time period. The study provided a brief overview on the challenges, support systems, and motivations of these nontraditional learners. Theories used to frame the study's conceptual framework and address its research questions included Biddle's (1979) Role Theory, McClusky's Theory of Margin, Load and Power (1971) and Tinto's (1975, 1993, 2012) and Bean and Metzner's (1985) …

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A Qualitative Inquiry Investigating The Inclusive Practices Of Teachers Within Catholic Schools, Alicia Abbey-Bell Jan 2017

A Qualitative Inquiry Investigating The Inclusive Practices Of Teachers Within Catholic Schools, Alicia Abbey-Bell

Electronic Theses and Dissertations

This phenomenological investigation examined the inclusive practices used to instruct students with disabilities in inclusive classrooms by educators within a large Catholic diocese in the southeast US. This study used phenomenological research methods to examine the perspectives, practices, and policies of Catholic school educators in inclusive settings through interviews, observations, and artifact reviews of school data to triangulate findings within this research. Surveys completed by administrators and faculty members provided initial knowledge and perspectives of inclusive practices for instruction of students with disabilities (SWDs) within inclusive settings. Structured interviews and classroom observation were then completed with participants at the school …

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A Comparison Of Sixth-, Seventh-, And Eighth-Grade Student Outcomes In Schools Configured K-8 Elementary Versus 6-8 Middle Schools As Measured By State Standardized Tests, Student Discipline Referrals, And Student Attendance, Jessica Kelce Jan 2017

A Comparison Of Sixth-, Seventh-, And Eighth-Grade Student Outcomes In Schools Configured K-8 Elementary Versus 6-8 Middle Schools As Measured By State Standardized Tests, Student Discipline Referrals, And Student Attendance, Jessica Kelce

Electronic Theses and Dissertations

The purpose of this study was to examine the differences in sixth-, seventh-, and eighth-grade students' outcomes in relation to school configuration, specifically K-8 elementary schools as compared to 6-8 middle schools. Student outcomes focused on in this study were standardized test scores, number of out-of-school suspensions, and number of days absent. Race and gender served as moderator variables for all research questions. Quantitative data were obtained from a large central Florida school district and included 2016 Florida Standards Assessment scale scores in English Language Arts, Mathematics, and Algebra 1 End-of-Course Examinations, 2015 Florida Standards Assessment scale scores in English …

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Sexual Violence Victimization And Prescription Drug Misuse: An Analysis Using General Strain Theory, Corey Pomykacz Jan 2017

Sexual Violence Victimization And Prescription Drug Misuse: An Analysis Using General Strain Theory, Corey Pomykacz

Electronic Theses and Dissertations

Sexual violence among college women is a widespread and severe public health issue in the United States. When compared to women in the general public, collegiate women are at an increased risk of sexual violence. Sexual violence can result in damaging and long-term consequences for the victim. Consequences of sexual violence include physical injuries, psychological distress, social withdrawal, poor grades and participation in health risk behaviors. While a connection between sexual violence victimization and negative outcomes is well established, most of the research in this area is atheoretical. To address this gap in the literature this study relied on Robert …

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Then And Now: Using Syllabi To Shape The College Classroom, Jessica Valentin Jan 2017

Then And Now: Using Syllabi To Shape The College Classroom, Jessica Valentin

Electronic Theses and Dissertations

While the college classroom has been researched, its climate has received little attention in research. This study analyzes the climate of the classroom using 189 syllabi from various sociology courses. Drawing from data collected by Grauerholz and Gibson (2006) and syllabi from the Teaching Resources and Innovations Library for Sociology (TRAILS), the current study compares college classroom syllabi from two different times periods (pre-2005 and post- 2010) to analyze the frequency of classroom climate statements, the variables that may contribute to the presence of a statement, and common language/themes existent in syllabi that did contain a statement. Results showed a …

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An Examination Of Novice And Expert Teachers' Pedagogy In A Mixed-Reality Simulated Inclusive Secondary Classroom Including A Student Avatar With Autism Spectrum Disorders, Taylor Bousfield Jan 2017

An Examination Of Novice And Expert Teachers' Pedagogy In A Mixed-Reality Simulated Inclusive Secondary Classroom Including A Student Avatar With Autism Spectrum Disorders, Taylor Bousfield

Electronic Theses and Dissertations

Teachers, special and general educators alike, are required to teach a variety of students including students with ASD. With a rise in the prevalence of autism by 119.4% since 2000 (Centers for Disease Control and Prevention [CDC], 2016) and 39% of students with ASD being served in general education classrooms for over 80% of the school day (U.S. Department of Education, 2015), teachers need to be prepared to effectively teach this population. To better prepare teachers, the researcher conducted a two-phase study, situated in the framework of the Skill Acquisition Model (Dreyfus & Dreyfus, 1986) to explore the behaviors of …

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An Analysis Of Robot-Assisted Social-Communication Instruction For Young Children With Autism Spectrum Disorders, Claire Donehower Jan 2017

An Analysis Of Robot-Assisted Social-Communication Instruction For Young Children With Autism Spectrum Disorders, Claire Donehower

Electronic Theses and Dissertations

Social and communication deficits are a core feature of Autism Spectrum Disorders (ASD) and impact an individual's ability to be a full participant in their school environment and community. The increase in number of students with ASD in schools combined with the use of ineffective interventions have created a critical need for quality social-communication instruction in schools for this population. Technology-based interventions, like robots, have the potential to greatly impact students with disabilities, including students with ASD who tend to show increased interest and engagement in technology-based tasks and materials. While research on the use of robots with these learners …

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An Sos Conceptual Model, Lvc Simulation Framework, And A Prototypical Implementation Of Unmanned System Interventions For Nuclear Power Plant Disaster Preparedness, Response, And Mitigation, Matthew Davis Jan 2017

An Sos Conceptual Model, Lvc Simulation Framework, And A Prototypical Implementation Of Unmanned System Interventions For Nuclear Power Plant Disaster Preparedness, Response, And Mitigation, Matthew Davis

Electronic Theses and Dissertations

Nuclear power plant disasters can have severe and far-reaching consequences, thus emergency managers and first responders from utility owners to the DoD must be prepared to respond to and mitigate effects protecting the public and environment from further damage. Rapidly emerging unmanned systems promise significant improvement in response and mitigation of nuclear disasters. Models and simulations (M&S) may play a significant role in improving readiness and reducing risks through its use in planning, analysis, preparation training, and mitigation rehearsal for a wide spectrum of derivate scenarios. Legacy nuclear reactor M&S lack interoperability between themselves and avatar or agent-based simulations of …

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How Does Brief Cognitive Behavioral Therapy Work? Potential Mechanisms Of Action For Veterans With Physical And Psychological Comorbidities, Frances Deavers Jan 2017

How Does Brief Cognitive Behavioral Therapy Work? Potential Mechanisms Of Action For Veterans With Physical And Psychological Comorbidities, Frances Deavers

Electronic Theses and Dissertations

Depression and anxiety are commonly comorbid among patients with chronic medical conditions. These comorbidities are associated with negative outcomes including poorer quality of life and worse physical functioning. Evidence that traditional cognitive behavioral therapy (CBT) is less effective for these populations has led to the development of brief CBT protocols that incorporate physical health self-management skills and are delivered in primary care. To continue refining treatment packages, it is important to understand how brief CBT works. The present study used the transactional model of stress and coping as a framework for investigating potential mechanisms of action of brief CBT. Veterans …

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Predicting Child Maltreatment Potential In Mothers Who Are Substance-Involved: A Study Of Childhood Adversity, Stress, Affectivity, Emotion Dysregulation, And Emotion Regulation Strategies As Mechanisms Of Action, Amanda Lowell Jan 2017

Predicting Child Maltreatment Potential In Mothers Who Are Substance-Involved: A Study Of Childhood Adversity, Stress, Affectivity, Emotion Dysregulation, And Emotion Regulation Strategies As Mechanisms Of Action, Amanda Lowell

Electronic Theses and Dissertations

Compared to the general population, parents who are substance-involved are both more likely to have experienced adversity during childhood and to exhibit elevated child maltreatment potential later in life. Within this population, mothers with young children are particularly at-risk. In order to enhance scientific understanding of this phenomenon, this study identified and examined several characteristics that were shown previously to be related to substance misuse and to the experience and perpetration of maltreatment. These characteristics included stress, affectivity, emotion dysregulation, and emotion regulation strategies. The current study examined these variables collectively in order to clarify the mechanisms at play in …

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The Effects Of The Vocabulary Scenario Technique- English Learner Peer Protocol On Ninth Grade English Learners Who Struggle With Literacy, Kimmerly Harrell Jan 2017

The Effects Of The Vocabulary Scenario Technique- English Learner Peer Protocol On Ninth Grade English Learners Who Struggle With Literacy, Kimmerly Harrell

Electronic Theses and Dissertations

Recent data have shown that only 34% of eighth graders and 37% of 12th graders were reading at or above proficiency (NAEP, 2015). A total of 21% of Hispanic eighth graders were reading at or above proficiency, and only 25% of Hispanic 12th graders were reading at or above proficiency. Of African-American students, 16% of eighth graders and 17% of 12th graders were reading at or above proficiency. In order for adolescents to become successful and productive adults, they need to acquire advanced literacy skills. Many of these demands require an education beyond high school (Rothman, 2012). Concern for English …

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Faculty Perspectives And Participation In Implementing An Early Alert System And Intervention In A Community College, Claudine Bentham Jan 2017

Faculty Perspectives And Participation In Implementing An Early Alert System And Intervention In A Community College, Claudine Bentham

Electronic Theses and Dissertations

Early alert systems have been recognized as a high impact practice designed to improve student engagement and student success. Early alert is designed to identify students with at-risk behaviors early in the semester before they decide to drop-out, withdraw, or fail their classes, using resources such as a predictive analysis tool or advising. For an early alert to be successful and efficient, faculty should be included in the process of early alert. This qualitative study examined faculty's perspective and experiences when implementing early alert strategies and intervention in a two-year institution. Using Cranton's seven facets of transformative learning as a …

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University Students' Citizenship Shaped By Service-Learning, Community Service, And Peer-To-Peer Civic Discussions, Haley Winston Jan 2017

University Students' Citizenship Shaped By Service-Learning, Community Service, And Peer-To-Peer Civic Discussions, Haley Winston

Electronic Theses and Dissertations

Citizenship is often referred to as the forgotten outcome of colleges and universities. The present study examined the relationship between undergraduate students' perceived citizenship level and different types of civic experiences (service-learning, community service, and peer-to-peer civic discussions) and also different demographic factors (gender, race/ethnicity, and parental level of education) at a public institution using the Personal and Social Responsibility Inventory. This study used structural equation modeling and multiple regression analysis. This marks the first time these variables have been researched together. This study found a significant correlation between both community service and peer-to-peer civic discussions in relation to citizenship …

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Load Estimation, Structural Identification And Human Comfort Assessment Of Flexible Structures, Ozan Celik Jan 2017

Load Estimation, Structural Identification And Human Comfort Assessment Of Flexible Structures, Ozan Celik

Electronic Theses and Dissertations

Stadiums, pedestrian bridges, dance floors, and concert halls are distinct from other civil engineering structures due to several challenges in their design and dynamic behavior. These challenges originate from the flexible inherent nature of these structures coupled with human interactions in the form of loading. The investigations in past literature on this topic clearly state that the design of flexible structures can be improved with better load modeling strategies acquired with reliable load quantification, a deeper understanding of structural response, generation of simple and efficient human-structure interaction models and new measurement and assessment criteria for acceptable vibration levels. In contribution …

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Jail Mental Health Innovations: Factors Influencing Mental Health Services Innovations For Jails, Orville Clayton Jan 2017

Jail Mental Health Innovations: Factors Influencing Mental Health Services Innovations For Jails, Orville Clayton

Electronic Theses and Dissertations

The U.S. is recognized for uniquely high incarceration rates. Over recent decades, there has been a concurrent dramatic increase of jail detainees with mental disorders. Provision of adequate mental health services for jail inmates is constitutionally mandated, and has legal, ethical, quality of care, and fiscal implications for jails, families, communities, and detainees. Significant variation exists in the provision of mental health services across jails, and increased understanding of the factors that influence the adoption of such services may help guide jails to implement beneficial services, and ensure that such services reflect, reflect quality standards. This study used a mixed …

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