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Cracking The Code Of Ai Autonomy: Examining The Role Of Challenge And Hindrance Appraisals And Ai Literacy In Task Satisfaction, Rujuta Parekar Jan 2026

Cracking The Code Of Ai Autonomy: Examining The Role Of Challenge And Hindrance Appraisals And Ai Literacy In Task Satisfaction, Rujuta Parekar

Graduate Studies Theses and Dissertations 2026

AI is constantly evolving and being rapidly integrated into the workplace. Limited research has examined how this integration is affecting employee outcomes, and particularly the impacts of whether employees are expected or mandated to use AI for their work. The present study utilized the challenge-hindrance framework to examine the effect of autonomy in using AI on task satisfaction through challenge and hindrance appraisal among working adults. Since the ability to understand and use AI can influence how individuals perceive it, the moderating effect of AI literacy on the hypothesized research model is also examined. A multi-wave research design was used …


Beyond The Square Pulse: Waveform Shape, Eeg Correlates, And The Pursuit Of Natural Sensation In Tens, Jason Whitson Jan 2026

Beyond The Square Pulse: Waveform Shape, Eeg Correlates, And The Pursuit Of Natural Sensation In Tens, Jason Whitson

Honors Undergraduate Theses

This study investigates the relationship between electrical stimulus characteristics of shape and charge on evoked sensations and electroencephalogram (EEG) data during multi-waveform transcutaneous electrical nerve stimulation (TENS) of the median nerve. Neuromodulation methods have traditionally had little control over the location and quality of their associated evoked sensation (e.g., electric, vibration, touch). This experiment utilized five unique stimulus waveforms during TENS stimulation. EEG data were collected concurrently to provide an introductory objective measure of the neural responses underlying these sensory changes. Eleven participants completed three tasks (thresholding, super-threshold stimulation, two-alternative forced choice) using a two-electrode TENS approach. Stimulus waveforms were …


Exploring Associations Between Mental Disorder And Creativity, David A. Romero Mora Jan 2026

Exploring Associations Between Mental Disorder And Creativity, David A. Romero Mora

Honors Undergraduate Theses

Mental disorder has been misunderstood and misrepresented throughout history, leading mental health research to be severely behind where it needs to be. Years of misinformation, over-medicalization, negative rhetoric, and stigmatization at the hands of the very same institutions that were believed to care for mental disorder have kept this misunderstanding alive. Further, studies throughout history have failed to look at the nuances of mental health, prioritizing generalizability. This thesis explores the relationship between mental disorder and creative expression, how other factors like cultural discourse and cognitive processes inform this relationship, as well as how analyzing this relationship can provide a …


Bilingualsim In The Workplace: How Work Attitudes Influence Burnout And Turnover Intentions, Andrea Del Aguila Jan 2026

Bilingualsim In The Workplace: How Work Attitudes Influence Burnout And Turnover Intentions, Andrea Del Aguila

Honors Undergraduate Theses

Understanding whether language status functions as a risk or protective factor for employee well-being and retention is essential for developing organizational policies that support workers from varied demographic backgrounds. This study examined how work attitudes such as job satisfaction, organizational commitment, and work engagement are seen among bilingual and monolingual workers and how these outcomes relate to employee burnout and turnover intentions. An outside researcher from Talent Metrics Consulting collected data via an online survey utilizing previously validated measures of job satisfaction, organizational commitment, burnout, work engagement, and turnover intentions. Participants were recruited through online advertising and social sampling obtaining …


Comparative Analysis Of Left Ventricular Sympathetic Axons In Shr And Wky Rats, Parker R. Tyson Jan 2026

Comparative Analysis Of Left Ventricular Sympathetic Axons In Shr And Wky Rats, Parker R. Tyson

Honors Undergraduate Theses

Hypertension is a leading cause of cardiovascular morbidity and mortality and is strongly associated with dysregulation of the sympathetic nervous system, which plays a central role in controlling heart rate, vascular tone, and blood pressure. Although increased sympathetic activity has been widely documented in hypertensive disease, the precise structural organization of sympathetic innervation within the hypertensive heart remains incompletely characterized. This study investigates whether chronic hypertension is associated with structural remodeling of sympathetic axons in the left ventricle by comparing autonomic innervation patterns between spontaneously hypertensive rats (SHR) and normotensive Wistar Kyoto rats (WKY). Hearts were collected following transcardial perfusion …


Complexity Theory And Environmental Conservation Management: A Case Study With Coyote And Red Wolf Hybridization, Gretchen E. Mahalic Jan 2026

Complexity Theory And Environmental Conservation Management: A Case Study With Coyote And Red Wolf Hybridization, Gretchen E. Mahalic

Honors Undergraduate Theses

Conservation biology and invasion biology are value-led scientific disciplines founded on environmental advocacy, operating at the intersection of research and action. Though these disciplines are known for their scientific veracity, unexamined values are often promulgated without scrutiny and drive decisions that work against good ecological outcomes. A case in point is that coyotes migrating into southeastern territory are framed as the greatest threat to the conservation of the endangered red wolf because hybridization is seen as diminishing their species integrity. Applying Val Plumwood’s ecofeminist account of dualistic frameworks, I will use this case to show how the vilification of the …


A Chicken Model For Non-Invasive Diagnosis Of Infant Developmental Dysplasia Of The Hip (Ddh) Using Acoustic Transmission Measurements, Aliza Shah Jan 2026

A Chicken Model For Non-Invasive Diagnosis Of Infant Developmental Dysplasia Of The Hip (Ddh) Using Acoustic Transmission Measurements, Aliza Shah

Honors Undergraduate Theses

Developmental dysplasia of the hip (DDH) is a condition characterized by abnormal development and stability of the hip joint. In a healthy infant, the femoral head (ball) fits securely within the acetabulum (socket of the pelvis), allowing for proper joint function. In DDH, the relationship is disrupted, ranging from mild acetabular dysplasia to partial (subluxation) or complete dislocation of the femoral head. This condition represents a range of structural abnormalities that develop during early growth. The integrity of the hip joint is essential for physical mobility, and disruption of this structure can lead to significant functional impairment. DDH may result …


Investigating The Role Of Traditional Chinese Herbal Medicine For Cancer Symptom Management In Older Adults: A Rapid Review, Isabelle C. Karshner Jan 2026

Investigating The Role Of Traditional Chinese Herbal Medicine For Cancer Symptom Management In Older Adults: A Rapid Review, Isabelle C. Karshner

Honors Undergraduate Theses

Background: Patients with cancer often experience symptoms related to disease, complications, and treatment. One potential method of alleviating these symptoms is traditional Chinese herbal medications (TCHM). This rapid review explores the role of traditional Chinese herbal medications in treating cancer-related symptoms in older adults.

Purpose: The purpose of this rapid review is to gain and provide a better understanding of the effects of TCHM on cancer-symptom management in the older adult population. This review explores the association between TCHM and effects on cancer symptoms in older adults, including interactions, toxicity, and signs/symptoms of TCHM use that may be useful information …


Synthesis And Characterization Of Succinate Dehydrogenase Inhibitors H2/Z14 And C6/Z96 In Order To Combat Small Cell Lung Cancer, Lauren M. Graves Jan 2026

Synthesis And Characterization Of Succinate Dehydrogenase Inhibitors H2/Z14 And C6/Z96 In Order To Combat Small Cell Lung Cancer, Lauren M. Graves

Honors Undergraduate Theses

The use of ubiquinone inhibitors to combat cancer is a recent development in medicinal science and procedures to efficiently synthesize these drugs remain limited. C6/Z96 and H2/Z14, two succinate dehydrogenase inhibitors, have been previously tested in vitro against NSCLC with positive results. Their similarity to ubiquinone is what makes them a strong candidate for a succinate dehydrogenase inhibitor at the ubiquinone binding site. The heterocyclic scaffolds and substituents are proposed to bind strongly through a combination of electronics, hydrogen-bonding, and fit, allowing them to bind well and prove to be more favorable than ubiquinone when competing for the Q-site. By …


A Test Of The Three-Step Theory: Examining Pain, Hopelessness, And Suicidal Desire Among College Students, Shelby Baker Jan 2026

A Test Of The Three-Step Theory: Examining Pain, Hopelessness, And Suicidal Desire Among College Students, Shelby Baker

Graduate Studies Theses and Dissertations 2026

Suicide is a leading cause of death, and suicidal thoughts are prevalent among emerging adults and undergraduate students. Still, many prominent risk factors remain understudied. Guided by the Three-Step Theory of Suicide (3ST), this study examined the roles of hopelessness, psychological pain, and physical pain in prediction of suicidal desire among undergraduate college students (N = 1,705) recruited from UCF’s SONA system and CloudResearch’s Connect platform. Participants completed an online, cross-sectional survey that included measures of suicidal thoughts and behaviors, hopelessness, psychological pain, physical pain, and other psychological variables of interest. Psychological pain and physical pain were tested as moderators …


Holistic Review In Graduate Admissions: Admissions Professionals’ Evaluation Of Non-Cognitive Traits, Joshua L. Olson Jan 2026

Holistic Review In Graduate Admissions: Admissions Professionals’ Evaluation Of Non-Cognitive Traits, Joshua L. Olson

Graduate Studies Theses and Dissertations 2026

This basic qualitative study examines how graduate admissions professionals conceptualize, operationalize, and interpret holistic review within graduate admissions processes. Guided by Social Cognitive Theory and Expectancy-Value Theory, the study explores how non-cognitive traits such as motivation, resilience, self-efficacy, and professionalism are evaluated alongside traditional academic indicators in admissions decision-making. Using semi-structured interviews with graduate admissions professionals directly involved in admissions decisions, the study identifies how holistic review is defined and implemented across institutional contexts, which non-cognitive traits are most valued, and the tools and procedures used to assess applicant potential beyond academic metrics. Findings suggest that, for participants in this …


Come And See: Exploring Complex Dynamics And Abjection Through A Southern Gothic Family Portrait, Lenee N. Peterson Jan 2026

Come And See: Exploring Complex Dynamics And Abjection Through A Southern Gothic Family Portrait, Lenee N. Peterson

Graduate Studies Theses and Dissertations 2026

“COME AND SEE: Exploring Abject Theory Through a Southern Gothic Family Portrait” examines the artist’s complex familial upbringing through the visual and narrative traditions of Southern Gothic art. Drawing upon abject theory and the cultural references of folk horror and Southern Gothicism, this thesis positions the family portrait where intimacy, trauma, and cultural inheritance collide. The project argues that direct confrontation with abjection can foster recognition, shared experience, and the possibility of collective healing. Grounded in practice-based research, this work functions as a critical and creative response to familial strain shaped by scarcity, social oppression, and emotional precarity. Through a …


Evaluation Of Electroencephalography Processing Methods For Estimating Metabolic Energy Expenditure During Walking, Stephanie L. Pinelo Jan 2026

Evaluation Of Electroencephalography Processing Methods For Estimating Metabolic Energy Expenditure During Walking, Stephanie L. Pinelo

Graduate Studies Theses and Dissertations 2026

In this study, three EEG datasets, created via different levels of pre-processing, were used to train VO2 prediction models whose performance was tested and compared. Understanding the link between EEG and VO2 during walking is important when working in rehabilitation or studying metabolic energy optimization. Common methods of measuring these two bio-signals tend to be bulky, uncomfortable, and inefficient, so finding a way to predict VO2 from EEG via 1D CNN model training is a worthy pursuit.  It was hypothesized that, due to a CNN needing more data to find patterns for prediction, a minimally processed EEG dataset would have …


Monitoring Shifts In Estuarine Microbial Communities: A Dna-Metabarcoding Approach, Ashley M. Reaume Jan 2026

Monitoring Shifts In Estuarine Microbial Communities: A Dna-Metabarcoding Approach, Ashley M. Reaume

Graduate Studies Theses and Dissertations 2026

Estuarine microbial communities, including plankton, algae, and bacteria, play important roles in nutrient cycling and food web structure. They are sensitive to changes in abiotic conditions, and shifts in community composition can provide insight into estuarine ecosystem functioning in the face of various physiochemical and anthropogenic stressors. Therefore, monitoring these communities is essential for understanding and maintaining estuarine health. DNA metabarcoding is an emerging technique for enhancing biological monitoring, allowing for the detection of multiple species within a single sample. This dissertation first focuses on how methodological decisions impact DNA metabarcoding results and then implements these optimized methods to perform …


Exercise-Induced Muscle Swelling And Impedance Changes Of The Elbow Flexor, Sofea Smith Jan 2026

Exercise-Induced Muscle Swelling And Impedance Changes Of The Elbow Flexor, Sofea Smith

Graduate Studies Theses and Dissertations 2026

Electrical impedance myography (EIM) is a non-invasive method that assesses body fluid distribution using impedance (Z), resistance (R), reactance (Xc), and phase angle (PhA). These values have previously been used to interpret cellular health and fluid shifts. Acute muscle edema known as a “pump,” has been reported during and after resistance training exercise and the extent to which bioelectrical properties of the muscle tissue are affected during this process remains relatively unexplored. Therefore, the purpose of this study was to assess changes in EIM during exercise-induced muscle swelling via resistance training. Thirty-one resistance-trained adults (male=21, female=10; age=23.4±6.5 years, BMI=26.17±3.04 kg/m2) …


Online Risk And Harm For Marginalized Users: How Social Influence Amplifies Or Mitigates Vulnerability, Tangila Islam Tanni Jan 2026

Online Risk And Harm For Marginalized Users: How Social Influence Amplifies Or Mitigates Vulnerability, Tangila Islam Tanni

Graduate Studies Theses and Dissertations 2026

Social media has reshaped how people connect, communicate, and influence one another, yet these environments also create harms that disproportionately affect marginalized users. Participation in online communities can expose users to identity-based harassment, emotional distress, and the normalization of harmful attitudes, shaping identity, well-being, and participation online and offline. Prior work has documented many forms of online harm, yet less is understood about how harmful norms and behaviors are reinforced across different forms of social media interaction, from private direct messages to online communities. Guided by the Social Ecological Model, this dissertation investigates how online harms toward marginalized users emerge …


Teachers’ Perceptions Of School Leaders’ Role In Implementing The Four Pillars Of Community Schools For Improving Student Achievement, Adrian Irwin Thomas Jan 2026

Teachers’ Perceptions Of School Leaders’ Role In Implementing The Four Pillars Of Community Schools For Improving Student Achievement, Adrian Irwin Thomas

Graduate Studies Theses and Dissertations 2026

This study examined teachers’ perceptions of school leaders’ roles in implementing the Four Pillars of Community Schools to support Student achievement in under-resourced schools. The four pillars of Community Schools- Integrated Student Support, Expanded Learning Time and Opportunities, Family and Community Engagement, and Collaborative Leadership and Practices- served as the conceptual framework for the study. Distributed Leadership Theory and Epstein’s Framework of Parental Involvement provided the theoretical lens that guided the interpretation of the findings. The study explored teachers’ perceptions of leadership practices associated with the four pillars and identified leadership strategies perceived as most effective for sustaining the community …


Bridging The Gap: How Sociodemographic Factors Shape Adults’ Decisions To Pursue Hearing Aids, Logan Lorié Jan 2026

Bridging The Gap: How Sociodemographic Factors Shape Adults’ Decisions To Pursue Hearing Aids, Logan Lorié

Graduate Studies Theses and Dissertations 2026

Despite hearing aids becoming more accessible to adults with hearing loss, hearing aid uptake rates remain low, partly due to sociodemographic factors that influence an adults’ decision to pursue amplification. This study systematically reviewed research on how sociodemographic factors – to include age, gender, socioeconomic status, education level, race/ethnicity, and military status – contribute to the decision-making process. This review guided an analysis of these variables using the National Health and Nutrition Examination Survey (NHANES), a large public health database. To ensure enough hearing aid users were included in the analysis, NHANES data were combined across survey cycles from 1999 …


Developing The Whole Child: A Retrospective Ethnographic Case Study Of Prosocial Learning Efforts At One Elementary School, Bevan Brown Jan 2026

Developing The Whole Child: A Retrospective Ethnographic Case Study Of Prosocial Learning Efforts At One Elementary School, Bevan Brown

Graduate Studies Theses and Dissertations 2026

An alarming trend among elementary-aged students in the United States exhibiting significant deficits in social-emotional competency development has intensified since the Covid-19 pandemic. Challenges in developing competent prosocial skills in the elementary-aged years have been associated with difficulties in emotional regulation and social interactions, which can result in compromising school readiness and long-term academic success. Existing school infrastructure provides a vehicle for early intervention, specifically in supporting students with poor social and emotional wellbeing. Thus, the need for innovative pedagogical and instructional approaches that address the complex challenges of the 21st century has become increasingly essential. Coordinated approaches to prosocial …


Perceptions Of High School Students’ Sports Participation And Potential Impact On Post-Secondary Involvement, Anthony J. Wishart Jan 2026

Perceptions Of High School Students’ Sports Participation And Potential Impact On Post-Secondary Involvement, Anthony J. Wishart

Graduate Studies Theses and Dissertations 2026

This dissertation examined the shifting culture of youth sports in the United States and its impact on academic motivation among adolescent student athletes. The study utilized Self-Determination Theory (SDT) as a framework. Traditionally, youth sports have helped students with personal growth and academic success. However, the contemporary emphasis on early sport specialization and the decline of opportunities in nonrevenue male sports are part of broader cultural shifts and require deeper exploration.

This study investigated the relationship between sport specialization among high school male junior and senior student athletes and their levels of academic motivation, as well as the consequences of …


Invisible Stress, Visible Patterns: How The Superwoman Schema Shapes Diet And Feeding Practices In Black Mothers And Their Youth During The Summer Versus School Months, Jillian Weathington Jan 2026

Invisible Stress, Visible Patterns: How The Superwoman Schema Shapes Diet And Feeding Practices In Black Mothers And Their Youth During The Summer Versus School Months, Jillian Weathington

Graduate Studies Theses and Dissertations 2026

Background: Black mothers are frequently socialized into the Superwoman Schema (SWS), a coping pattern characterized by self-sacrifice and suppression of personal needs. Alongside significant caregiving demands, SWS may limit healthy eating opportunities, yet its relationship with diet quality (DQ) remains understudied. SWS may also intensify during unstructured summer periods. This study examined associations between SWS, perceived stress, and DQ among Black mothers and their youth during summer (T1) and school months (T2).

Methods: This observational within-subjects study included Black mothers (T1: n=51; T2: n=32; mean age 39.6±6.1) and their youth (mean age 10.6±0.3). Assessments occurred at two timepoints six weeks …


The Impact Of Criminal Justice System Contact On Adolescents In The U.S.: Prescription Drug Misuse, Marijuana Use, Health Outcomes, And Demographic Characteristics, Fadime Gokce Karaaslan Jan 2026

The Impact Of Criminal Justice System Contact On Adolescents In The U.S.: Prescription Drug Misuse, Marijuana Use, Health Outcomes, And Demographic Characteristics, Fadime Gokce Karaaslan

Graduate Studies Theses and Dissertations 2026

Criminal justice system (CJS) contact remains a pervasive feature of social life in the United States, with both direct and indirect consequences for adolescents and their families. Although previous research has explored the consequences of direct CJS contact, less is known about how indirect or vicarious contact affects adolescents’ well-being and substance use. Drawing on data from the Future of Families and Child Wellbeing Study (FFCWS), this study investigates the association between parental incarceration and vicarious police stops, defined as police stops involving parents, siblings, friends, neighbors, or other social ties, and adolescent well-being. Findings indicate that CJS contact is …


Gaining Voice, Creating Opportunity: An Exploration Of Non-Native English-Speaking Students’ Sources Of Self-Efficacy In U.S. College Public Speaking Classrooms, Desiree M M Flores-Molina Jan 2026

Gaining Voice, Creating Opportunity: An Exploration Of Non-Native English-Speaking Students’ Sources Of Self-Efficacy In U.S. College Public Speaking Classrooms, Desiree M M Flores-Molina

Graduate Studies Theses and Dissertations 2026

This qualitative dissertation explores the sources of public speaking self-efficacy among non-native English-speaking international students enrolled in U.S. college public speaking courses. The study applies Bandura's social cognitive theory to examine how students describe the experiences that shape their confidence and perceived ability to succeed, with attention to mastery experiences, vicarious experiences, verbal persuasion, and physiological and affective states. It also considers how classroom practices and instructor support contribute to or constrain students' confidence.

Data were collected through semi-structured student interviews, guided reflection artifacts connected to major speech assignments, and key-informant interviews with public speaking instructors. Thematic analysis was used …


Establishment Of An In Vitro Dss-Induced Epithelial Injury Model To Investigate Il-6 Signaling And Microbial Metabolite Mediated Barrier Recovery, Srijal Kunwar Jan 2026

Establishment Of An In Vitro Dss-Induced Epithelial Injury Model To Investigate Il-6 Signaling And Microbial Metabolite Mediated Barrier Recovery, Srijal Kunwar

Graduate Studies Theses and Dissertations 2026

Dextran sodium sulphate (DSS) is widely used in vivo to induce epithelial injury; however, the molecular effects of DSS on intestinal epithelial cells, that investigate inflammatory and metabolic repair mechanisms remain unclear. Here, we establish an in vitro DSS-induced epithelial damage model using differentiated Caco-2 cell monolayer. Exposure to 2.5%(w/v) DSS for 24 hours resulted in significant upregulation of pore forming protein Claudin-2(2.677-fold) and oxidative marker, NOX-1(1.866-fold), accompanied by increased ROS production confirmed via DHE staining. Increased epithelial permeability was observed by TEER analysis, without significant cytotoxicity. Surprisingly, ELISA analysis revealed significant downregulation of IL-6 (p-value …


The Amanah Project: A Pilot Educational Intervention Addressing Intimate Partner Violence In Muslim Communities In The United States, Tamara Makki Jan 2026

The Amanah Project: A Pilot Educational Intervention Addressing Intimate Partner Violence In Muslim Communities In The United States, Tamara Makki

Graduate Studies Theses and Dissertations 2026

This study is a two-part manuscript dissertation that addresses the need for culturally and faith-based responsive interventions for intimate partner violence (IPV) within the Muslim community in the United States (U.S). The first manuscript is a conceptual and literature-based paper that examines IPV within the Muslim community in the U.S. and explores the intersection of religion, culture, patriarchy, and systemic barriers influencing survivors’ help-seeking experiences. Particular attention is given to issues of accessibility, including the limited availability of culturally and religiously responsive IPV services for Muslim survivors. This manuscript argues for the development of culturally responsive, faith-integrated approaches that improve …


Coordinated Whole-Body Dynamic Pressing And Reaction Inhibition — Impact Of High-Intensity Intermittent Exercise And Dehydration, Modesto A. Lebron Jan 2026

Coordinated Whole-Body Dynamic Pressing And Reaction Inhibition — Impact Of High-Intensity Intermittent Exercise And Dehydration, Modesto A. Lebron

Graduate Studies Theses and Dissertations 2026

Dynamic whole-body pressing movements are an imperative aspect of various sport and occupational settings, requiring motor coordination to kinetically sequence from lower- to upper-extremities. Recently, exercises such as the jammer arm punch press (JPP) have increased in popularity, promoted as an exercise to improve strength and force transfer. While the JPP has observed increased practical utility, its use in research is limited potentially due to difficulties with quantifying exercise intensity. One method to quantify exercise intensity is the assessment of velocity, serving as the basis for velocity-based training. For optimization, this strategy requires an understanding of velocity ranges and their …


A Systematic Review And Characterization Of Privacy Noncompliance In Real-World Applications, Alexander E. Charkiewicz Jan 2026

A Systematic Review And Characterization Of Privacy Noncompliance In Real-World Applications, Alexander E. Charkiewicz

Graduate Studies Theses and Dissertations 2026

Software applications increasingly rely on user data to provide their functionality, but improper handling of such data can lead to serious privacy noncompliance with applicable regulations and policies. A prominent example is the Facebook–Cambridge Analytica scandal, in which a third-party application collected the personal data of approximately 87 million Facebook users without users' consent. Despite growing attention to privacy compliance, two key challenges hinder the systematic understanding and analysis of privacy noncompliance. First, unlike security vulnerabilities, which have been systematically categorized through taxonomies such as the Common Weakness Enumeration (CWE), privacy noncompliance lacks a technical taxonomy describing how it manifests …


Toward Evidence-Based Disposition Assessment In Counselor Education: Advocating For Established Measures And Evaluating The Psychometric Properties Of The Pdca-Ra, Laura Rendon Finnell Jan 2026

Toward Evidence-Based Disposition Assessment In Counselor Education: Advocating For Established Measures And Evaluating The Psychometric Properties Of The Pdca-Ra, Laura Rendon Finnell

Graduate Studies Theses and Dissertations 2026

Professional dispositions are recognized as an essential component of counselor competence and are now explicitly included within accreditation standards. However, questions remain regarding how these characteristics should assessed in ways that are fair, systematic, and supported by empirical evidence. This two-manuscript dissertation focused on professional disposition assessment in counselor education. The first manuscript provides a conceptual examination of professional dispositions, counselor competence, and gatekeeping responsibilities while reviewing established disposition assessment instruments in counselor education. The manuscript advocates for the use of established disposition measures rather than relying solely on locally developed assessment procedures. The second manuscript presents an empirical evaluation …


Evaluating Novel Targeted Combination Therapies For Gastrointestinal Cancers, Joseph A. Goode Jan 2026

Evaluating Novel Targeted Combination Therapies For Gastrointestinal Cancers, Joseph A. Goode

Graduate Studies Theses and Dissertations 2026

Gastrointestinal (GI) cancers remain among the leading causes of cancer-related mortality worldwide, with therapeutic resistance continuing to limit the effectiveness of current treatments. Three complementary studies were conducted to identify therapeutic vulnerabilities and evaluate novel combination strategies in pancreatic ductal adenocarcinoma (PDAC) and colorectal cancer (CRC).  First, dual inhibition of fibroblast growth factor receptor 4 (FGFR4) and phosphoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) signaling was investigated in PDAC models. A combination of targeted drug treatments reduced viability, clonogenic survival, migration, and suppressed signaling pathways involved in translational control. This supported a functional interaction between FGFR4 and PI3K-mTOR co-activation in …


Concept Drift Detection For Streaming Data Using One-Class Classification, Poorna Sandamini Senaratne Jan 2026

Concept Drift Detection For Streaming Data Using One-Class Classification, Poorna Sandamini Senaratne

Graduate Studies Theses and Dissertations 2026

Modern machine learning systems are increasingly deployed in streaming environments where data arrive sequentially and the underlying data-generating process may evolve over time. This phenomenon, known as concept drift, can significantly degrade model performance if not detected and addressed in a timely manner. This dissertation proposes a principled framework for concept drift detection based on one-class classification, integrating neural network embeddings with Support Vector methodologies.

The proposed approach leverages neural networks to learn compact and informative embeddings of input data, capturing complex nonlinear structures in a lower-dimensional latent space. These embeddings are then used to construct a statistical description of …