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Biogeography And Systematics Of The Nerodia Clarkii/Nerodia Fasciata Clade In Florida, Gregory Territo Jan 2013

Biogeography And Systematics Of The Nerodia Clarkii/Nerodia Fasciata Clade In Florida, Gregory Territo

Electronic Theses and Dissertations

Biogeography provides a window into the evolutionary history of populations, and helps explain the diversity and distribution of life through time. Viewed from a systematic perspective, biogeographic studies generate convincing arguments to explain the relationships among organisms and categorize them into useful taxonomies. When taxonomies do not reflect evolutionary histories, inaccurate representations of biodiversity confound future studies and conservation efforts. Two thamnophiine snakes, Nerodia clarkii and Nerodia fasciata, harbor unique morphological and ecological adaptations that obscured natural groupings, leading to controversial taxonomic delimitations. Additionally, population declines documented in N. clarkii compressicauda and N. clarkii taeniata led managers to list N. …


Design, Synthesis, And Biological Evaluation Of Novel Polyamine Transport System Probes And Their Application To Human Cancers, Aaron Muth Jan 2012

Design, Synthesis, And Biological Evaluation Of Novel Polyamine Transport System Probes And Their Application To Human Cancers, Aaron Muth

Electronic Theses and Dissertations

The mammalian polyamine transport system (PTS) has been of interest due to its roles in cancer and maintaining cellular homeostasis. Polyamines are essential growth factors which are tightly controlled via a balance of biosynthesis, metabolism, import, and export. This work focused on the development and biological testing of polyamine transport probes to help understand the molecular requirements of the PTS. This was mediated through the use of a CHO (PTS active) and CHO-MG* (PTS deficient) screen, where compounds demonstrating high toxicity in CHO and low toxicity in CHO-MG* were considered PTS selective. The first chapter focused on the development of …


Biochemical Studies Of Abce1, Lynn Sims Jan 2012

Biochemical Studies Of Abce1, Lynn Sims

Electronic Theses and Dissertations

The growth and survival of all cells require functional ribosomes that are capable of protein synthesis. The disruption of the steps required for the function of ribosomes represents a potential future target for pharmacological anti-cancer therapy. ABCE1 is an essential Fe-S protein involved in ribosomal function and is vital for protein synthesis and cell survival. Thus, ABCE1 is potentially a great therapeutic target for cancer treatment. Previously, cell biological, genetic, and structural studies uncovered the general importance of ABCE1, although the exact function of the Fe-S clusters was previously unclear, only a simple structural role was suggested. Additionally, due to …


Spatial Ability And Experts Of Needlework Crafts An Exploratory Study, Shannon Kyle Tedder Bailey Dec 2011

Spatial Ability And Experts Of Needlework Crafts An Exploratory Study, Shannon Kyle Tedder Bailey

HIM 1990-2015

In the Surface Development Test, self-perceived Sewing Expertise was significant in predicting participants' test scores. For the Paper Folding Test, Knitting and Crocheting Expertise were significant, suggesting expertise may mitigate age effects.; Spatial ability has been a topic of much research and debate over the past few decades. Yet, there are gaps in the current literature. Spatial ability refers to the aptitude of an individual to mentally rotate objects, visualize spaces, and recognize patterns (Linn & Petersen, 1985). A highly spatial task that is not addressed in research literature is crafting. Crafting may refer to knitting, crocheting, sewing, and other …


Lipophilic Polyamines Providing Enhanced Intracellular Delivery Of Agents By A Polyamine Transport System, Otto Phanstiel, Kenneth Teter Mar 2011

Lipophilic Polyamines Providing Enhanced Intracellular Delivery Of Agents By A Polyamine Transport System, Otto Phanstiel, Kenneth Teter

UCF Patents

All cells require polyamines in order to grow. Many cell types (including cancer cells) have active polyamine transporters which import extracellular polyamines into the cell. Our invention is the development of new lipophilic polyamines which can access cells via their polyamine transport system. The long lipid tails facilitate the formation of assembled complexes which are recognized and imported into cells. The invention describes several examples of using this technology for drug delivery and includes: a) the efficient delivery of foreign DNA into Chinese hamster ovary cells and expression of the protein encoded by the foreign DNA; and b) the delivery …


Airtight Container For The Transfer Of Atmosphere-Sensitive Materials Into Vacuum-Operated Characterization Instruments, Romain M. Gaume, Lydia-Marie Joubert Jan 2011

Airtight Container For The Transfer Of Atmosphere-Sensitive Materials Into Vacuum-Operated Characterization Instruments, Romain M. Gaume, Lydia-Marie Joubert

Faculty Bibliography 2010s

This paper describes the design and operation of a simple airtight container devised to facilitate the transfer of atmosphere-sensitive samples from a glovebox to the vacuum chamber of an analytical instrument such as a scanning electron microscope. The use of this device for characterizing the microstructure of highly hygroscopic strontium iodide ceramics by scanning electron microscopy is illustrated as an application example.


An Investigation Of The Effects Of Using Digital Flash Cards To Increase Biology Vocabulary Knowledge In High School Students With Learning Disabilities, Kelly J. Grillo Jan 2011

An Investigation Of The Effects Of Using Digital Flash Cards To Increase Biology Vocabulary Knowledge In High School Students With Learning Disabilities, Kelly J. Grillo

Electronic Theses and Dissertations

The field of science education, specifically biology, is becoming more challenging due to richer and more rigorous content demands. Along with new demands is the emergence of National Common Core Standards and End of Course Exams. Despite these changes, one factor remains consistent: As content knowledge increases, language demands also increase. For students with learning disabilities (LD), specifically those with language-based disabilities, the increasing vocabulary demand can lead to failure due not to a lack of understanding biology but the vocabulary associated with the content. In an attempt to impact high school students with learning disabilities‘ success in biology, a …


Carbon Nanotube Collimators: Fabrications And Applications, Lee Chow, Guang Chai, Thomas Schenkel Jul 2010

Carbon Nanotube Collimators: Fabrications And Applications, Lee Chow, Guang Chai, Thomas Schenkel

UCF Patents

Apparatus, methods, systems and devices for fabricating individual CNT collimators. Micron size fiber coated CNT samples are synthesized with chemical vapor deposition method and then the individual CNT collimators are fabricated with focused ion beam technique. Unfocused electron beams are successfully propagated through the CNT collimators. The CNT nano-collimators are used for applications including single ion implantation and in high-energy physics, and allow rapid, reliable testing of the transmission of CNT arrays for transport of molecules.


Autonomous Evolution Of Topographic Regularities In Artificial Neural Networks, Jason Gauci, Kenneth O. Stanley Jan 2010

Autonomous Evolution Of Topographic Regularities In Artificial Neural Networks, Jason Gauci, Kenneth O. Stanley

Faculty Bibliography 2010s

Looking to nature as inspiration, for at least the past 25 years, researchers in the field of neuroevolution (NE) have developed evolutionary algorithms designed specifically to evolve artificial neural networks (ANNs). Yet the ANNs evolved through NE algorithms lack the distinctive characteristics of biological brains, perhaps explaining why NE is not yet a main-stream subject of neural computation. Motivated by this gap, this letter shows that when geometry is introduced to evolved ANNs through the hypercube-based neuroevolution of augmenting topologies algorithm, they begin to acquire characteristics that indeed are reminiscent of biological brains. That is, if the neurons in evolved …


Multi-Modal Reading For Low Level Readers, Jamie O'Neal Jan 2010

Multi-Modal Reading For Low Level Readers, Jamie O'Neal

Electronic Theses and Dissertations

The value of this research hinges on the idea that exchanging illustrations for descriptive text can provide appropriate schemas for students with reading difficulties and thereby improve their comprehension and vocabulary acquisition. The research in this dissertation is based on theories and earlier research in the fields of psychology, education, reading, and narratology. A review of these fields offers a variety of perspectives on the processes involved in reading and comprehension. These processes range from the physical systems involved in reading (e.g., early childhood development, eye movement) to the psychological systems, which include cognitive load theory as well as image …


Design, Synthesis, And Characterization Of Novel Hydrophilic Fluorene-Based Derivatives For Bioimaging Applications, Dao Nguyen Jan 2009

Design, Synthesis, And Characterization Of Novel Hydrophilic Fluorene-Based Derivatives For Bioimaging Applications, Dao Nguyen

Electronic Theses and Dissertations

In this work, hydrophilic fluorene-based derivatives that contain ethylene oxide substituents, have been synthesized and characterized for potential use as new fluorophores for bioimaging applications and for fluorescence sensing of heavy metals. Symmetrical and unsymmetrical fluorene derivatives based on structural types of acceptor-pi-acceptor, acceptor-pi-donor, and donor-pi-donor were characterized by TGA, UV-vis absorption, fluorescence emission, lifetime, anisotropy, and two-photon absorption (2PA) cross section. They were found to possess high thermal stability, high photostability, high fluorescence quantum yields, and generally large two-photon absorption cross sections, making them quite suitable for new probes in single-photon absorption and two-photon absorption fluorescence microscopy imaging. Novel …


Sandspur, Vol 115, No 08, October 17, 2008, Rollins College Oct 2008

Sandspur, Vol 115, No 08, October 17, 2008, Rollins College

The Rollins Sandspur

Rollins College student newspaper, written by the students and published at Rollins College. The Sandspur started as a literary journal.


A Point Mutation In The Two-Component Regulator Phop-Phor Accounts For The Absence Of Polyketide-Derived Acyltrehaloses But Not That Of Phthiocerol Dimycocerosates In Mycobacterium Tuberculosis H37ra, Marie-Laure Chesne-Seck, Nathalie Barilone, Frédéric Boudou, Jesús Gonzalo Asensio, Pappachan E. Kolattukudy, Carlos Martín, Stewart T. Cole, Brigitte Gicquel, Deshmukh N. Gopaul, Mary Jackson Jan 2008

A Point Mutation In The Two-Component Regulator Phop-Phor Accounts For The Absence Of Polyketide-Derived Acyltrehaloses But Not That Of Phthiocerol Dimycocerosates In Mycobacterium Tuberculosis H37ra, Marie-Laure Chesne-Seck, Nathalie Barilone, Frédéric Boudou, Jesús Gonzalo Asensio, Pappachan E. Kolattukudy, Carlos Martín, Stewart T. Cole, Brigitte Gicquel, Deshmukh N. Gopaul, Mary Jackson

Faculty Bibliography 2000s

Similarities between Mycobacterium tuberculosis phoP-phoR mutants and the attenuated laboratory strain M. tuberculosis H37Ra in terms of morphological and cytochemical properties, lipid content, gene expression and virulence attenuation prompted us to analyze the functionality of this two-component regulator in the latter strain. Sequence analysis revealed a base substitution resulting in a one-amino-acid change in the likely DNA-binding region of PhoP in H37Ra relative to H37Rv. Using gel-shift assays, we show that this mutation abrogates the ability of the H37Ra PhoP protein to bind to a 40-bp segment of its own promoter. Consistent with this result, the phoP gene from H37Rv …


Alayzing The Effects Of Modularity On Search Spaces, Ozlem Garibay Jan 2008

Alayzing The Effects Of Modularity On Search Spaces, Ozlem Garibay

Electronic Theses and Dissertations

We are continuously challenged by ever increasing problem complexity and the need to develop algorithms that can solve complex problems and solve them within a reasonable amount of time. Modularity is thought to reduce problem complexity by decomposing large problems into smaller and less complex subproblems. In practice, introducing modularity into evolutionary algorithm representations appears to improve search performance; however, how and why modularity improves performance is not well understood. In this thesis, we seek to better understand the effects of modularity on search. In particular, what are the effects of module creation on the search space structure and how …


Retrocyclin Rc-101 Overcomes Cationic Mutations On The Heptad Repeat 2 Of Hiv-1 Gp41, Christopher Fuhrman Jan 2007

Retrocyclin Rc-101 Overcomes Cationic Mutations On The Heptad Repeat 2 Of Hiv-1 Gp41, Christopher Fuhrman

Electronic Theses and Dissertations

Retrocyclin RC-101, a θ-defensin with lectin-like properties, potently inhibits infection by many HIV-1 subtypes by binding to the heptad repeat (HR)-2 region of gp41 and preventing six-helix bundle formation. In the present study, we used in silico computational exploration to identify residues of HR2 that interacted with RC-101 and then analyzed the HIV-1 Sequence Database at LANL for residue variations in the HR1 and HR2 segments that could plausibly impart in vivo resistance. Docking RC-101 to gp41 peptides in silico confirmed its strong preference for HR2 over HR1, and implicated residues crucial for its ability to bind HR2. We mutagenized …


Fundamental Aspects Of Regenerative Cerium Oxide Nanoparticles And Their Applications In Nanobiotechnology, Swanand Patil Jan 2006

Fundamental Aspects Of Regenerative Cerium Oxide Nanoparticles And Their Applications In Nanobiotechnology, Swanand Patil

Electronic Theses and Dissertations

Cerium oxide has been used extensively for various applications over the past two decades. The use of cerium oxide nanoparticles is beneficial in present applications and can open avenues for future applications. The present study utilizes the microemulsion technique to synthesize uniformly distributed cerium oxide nanoparticles. The same technique was also used to synthesize cerium oxide nanoparticles doped with trivalent elements (La and Nd). The fundamental study of cerium oxide nanoparticles identified variations in properties as a function of particle size and also due to doping with trivalent elements (La and Nd). It was found that the lattice parameter of …


Synthesis, Characterizations, And Evaluation Of New Reactive Two-Photon Absorbing Dyes For Two-Photon Excited Fluorescence Imaging Applications, Katherine J. Hales Jan 2005

Synthesis, Characterizations, And Evaluation Of New Reactive Two-Photon Absorbing Dyes For Two-Photon Excited Fluorescence Imaging Applications, Katherine J. Hales

Electronic Theses and Dissertations

Recent, cooperative advances in chemistry, biology, computing, photophysics, optics, and microelectronics have resulted in extraordinary developments in the biological sciences, resulting in the emergence of a novel area termed 'biophotonics'. The integrative and interdisciplinary nature of biophotonics cuts across virtually all disciplines, extending the frontiers of basic cellular, molecular, and biology research through the clinical and pharmaceutical industries. This holds true for the development and application of the novel imaging modality utilizing multiphoton absorption and its extraordinary contribution to recent advances in bioimaging. Intimately involved in the revolution of nonlinear bioimaging has been the development of optical probes for probing …


Part I : Isolation Of Dipentyl 2-(4-(Pentan-3-Yl) Phenyl) Malonate From Sanguisorba Officinalis Labill Part Ii: Synthesis Of A Novel Family Of Ethers Of Podocarpic Acid, Manjeera Yalavarty Jan 2005

Part I : Isolation Of Dipentyl 2-(4-(Pentan-3-Yl) Phenyl) Malonate From Sanguisorba Officinalis Labill Part Ii: Synthesis Of A Novel Family Of Ethers Of Podocarpic Acid, Manjeera Yalavarty

Electronic Theses and Dissertations

The goal of part I of this thesis was to isolate pure anti cancer compounds from the Russian plant Sanguisorba officinalis. This plant was selected for investigation because it showed 100% activity against leukemia (L1210 mouse leukemia cells) during the preliminary screening of approximately 100 Russian plant extracts. This work has resulted in the isolation of novel compound 11 using traditional chromatography techniques. Compound 11 was characterized with spectroscopic techniques such as IR, 1H NMR, 13C NMR, DEPT, DQCOSY and MS. Compound 11 was assigned the structure dipentyl 2-(4-(pentan-3-yl) phenyl) malonate. The goal of part II of this thesis was …


Synthesis Of A Novel Family Of Amide Derivatives Of Podocarpic Acid, Dao Nguyen Jan 2004

Synthesis Of A Novel Family Of Amide Derivatives Of Podocarpic Acid, Dao Nguyen

Electronic Theses and Dissertations

As a class, amides are of great interest in biological studies and pharmaceutical application. In this work, podocarpic acid, a natural tricyclic diterpene, derived from Podocarpus species, has been employed to form a novel family of amide derivatives which will later be studied for their potential as new drug leads. Novel amide derivatives of podocarpic acid were synthesized from podocarpic acid in three steps. The first step involved methylation with dimethylsulfate to form methyl-O-methylpodocarpate. This step was followed by iodination with iodine to give iodomethyl-O-methylpodocarpate. Finally amidation with various aliphatic amides using a copper catalyst yielded four amide derivatives of …


Configurations, Materials And Wavelenghts For Euv Lithium Plasma Discharge Lamps, William Silfvast, Marc Klosner Oct 1999

Configurations, Materials And Wavelenghts For Euv Lithium Plasma Discharge Lamps, William Silfvast, Marc Klosner

UCF Patents

This invention relates to Lithium Plasma discharge sources, and in particular to methods of making and producing pulsed and continuous discharge sources for plasma soft-x-ray or EUV projection lithography. Specifically, novel configurations, metal and ceramic material combinations and efficient wavelengths over and including 11.4 nm are disclosed for EUV lithium plasma discharge lamps.


Efficient Narrow Spectral Width Soft X-Ray Discharge Sources, William Silfvast Mar 1996

Efficient Narrow Spectral Width Soft X-Ray Discharge Sources, William Silfvast

UCF Patents

Methods for making pulsed and continuous discharge plasma light sources for extreme ultraviolet(EUV) projection lithography and soft-x-ray microscopy as well as other applications are disclosed. A first light source of doubly ionized lithium ions emits over a narrow bandwidth of approximately 13.5 nm. A second light source of beryllium ions radiates at approximately 7.60 nm. A third light source of boron ions radiates at approximately 4.86 nm, and a fourth light source of carbon ions radiates at approximately 3.38 nm. Preferred embodiments of apparatus for generating pulsed and continuous discharge sources are disclosed.


Counterpropagation Neural Network Detection Of Visual Primitives, Cynthia Lynn Johnson Jan 1990

Counterpropagation Neural Network Detection Of Visual Primitives, Cynthia Lynn Johnson

Retrospective Theses and Dissertations

Psychological testing has shown that there is an early preattentive stage in the human visual system. At this level, simple features and properties of objects known as visual primitives are detected spatially in parallel by groupings of cells in the visual cortex known as feature maps. In order to study this preattentive stage in a machine vision system, the biologically inspired, highly parallel architecture of the artificial neural network shows great promise. This paper describes how the unique architecture of the counterpropagation neural network was used to simulate the feature maps which detect visual primitives in the human visual system. …


Inoculation Theory: Motivation Mechanism Vs. Attack Credibility As Mediators Of Resistance To Persuasion, Peter F. Cranis Jan 1988

Inoculation Theory: Motivation Mechanism Vs. Attack Credibility As Mediators Of Resistance To Persuasion, Peter F. Cranis

Retrospective Theses and Dissertations

No abstract provided.


Breeding Biology Of The Great Crested Flycatcher, Myiarchus Crinitus, (Linnaeus) In Central Florida, Mark A. Kershner Jan 1985

Breeding Biology Of The Great Crested Flycatcher, Myiarchus Crinitus, (Linnaeus) In Central Florida, Mark A. Kershner

Retrospective Theses and Dissertations

No abstract provided.


Part I: The Synthesis Of New Potential Insecticides. Part Ii: New Aromatic Nucleophililic Subsitution Reactions, Fluoroalkoxylation And N,N-Dimethylamination, Cesar Colon Oct 1983

Part I: The Synthesis Of New Potential Insecticides. Part Ii: New Aromatic Nucleophililic Subsitution Reactions, Fluoroalkoxylation And N,N-Dimethylamination, Cesar Colon

Retrospective Theses and Dissertations

A series of routes are described for the synthesis of new potential insecticides which are symmetrical or asymmetrical similogs of 2,5-Bis (dichloropheny1)-1,3,4-oxadiazole and its precursor diacyl hydrazine. Also two new aromatic nucleophilic substitution reactions are discussed. Activated aryl halides are reacted with fluorinated alkoxide anions. In all cases, substitution of the halogen by a fluoroalkoxy group was observed, and activated aryl halides are reacted with HMPA as an N, N-dimethyl aminating agent. In all cases, substitution of the halogen by a dimethyl amino group was observed. The effect of the activating group and the leaving group is described and a …


Synthesis Of Potential Insecticides And New Synthetic Applications Of Vinamidinium And Azavinamidinium Salts: Reactions With Reducing Agents And Nitro Compounds, Michael J. Lizzi Apr 1982

Synthesis Of Potential Insecticides And New Synthetic Applications Of Vinamidinium And Azavinamidinium Salts: Reactions With Reducing Agents And Nitro Compounds, Michael J. Lizzi

Retrospective Theses and Dissertations

This report discusses the research conducted in two areas: the synthesis of potential insecticides and the investigation of vinamidinium and azavinamidinium salt chemistry. Firstly, four classes of compounds were synthesized and characterized in the investigation of new potential insecticides. These classes of compounds include a-formamidine methyl esters, amidines, diacylhydrazines and 2,5-disubstituted-1,3,4-oxadiazoles and were characterized via NMR and infrared spectroscopy. This account also reveals and discusses the experimental conditions and procedures necessary for the preparation of these potential insecticides. Secondly, the reaction of [ 3-(dimethyl amino)-2-azaprop-2-en-1-ylidene] dimethyl ammonium chloride (Gold's Reagent) with nucleophiles such as activated (nitro) methylene compounds was examined …


Florida Technological University College Of Natural Sciences Research Activities, July 1, 1975-June 30, 1976, Florida Technological University. College Of Natural Sciences Jan 1976

Florida Technological University College Of Natural Sciences Research Activities, July 1, 1975-June 30, 1976, Florida Technological University. College Of Natural Sciences

Research Activities & Annual Reports

Florida Technological University, College of Natural Sciences, research activities including funded research, non-sponsored research projects, presentations of professional papers, doctoral dissertations completed, and faculty publications for the year July 1, 1975-June 30, 1976.


Central Florida Future, Vol. 04 No. 34, July 28, 1972, Florida Technological University Jul 1972

Central Florida Future, Vol. 04 No. 34, July 28, 1972, Florida Technological University

Central Florida Future

Pre-registration terminated: Decision reached at June meeting (with photos of the registration crowd and the FTU administrators and college deans); July research grants fund major projects; Environment Institute ends 10-week broadcast series; FuTUre Editorials: It's gone… but why? Regents okay new engr. degree; Education chapter expands; 'Secret treasures' fill speech clinic; FTU gets $39,600; Low polluting MAX in urban design test (with photo); Fear not, I bring tidings... (with photo of FTU's three Sentinel interns); Station to open despite $ lack; 'New' WFTU radio airs in fall; FuTUre Entertainment: 'Cabaret': Close-up of '30s.


Sandspur, Vol. 72 No. 09, April 11, 1966, Rollins College Apr 1966

Sandspur, Vol. 72 No. 09, April 11, 1966, Rollins College

The Rollins Sandspur

Rollins College student newspaper, written by the students and published at Rollins College. The Sandspur started as a literary journal.


Archaeological Reconnaissance Of The Island Of St. John, United States Virgin Islands, Frederick W. Sleight Jan 1962

Archaeological Reconnaissance Of The Island Of St. John, United States Virgin Islands, Frederick W. Sleight

British West Indies Text

No abstract provided.