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Dysbiosis In Parkinson's Disease: A Meta-Analysis Of Gut Microbiota And Its Role In Gastrointestinal Dysfunction And Disease Progression, Ayan M. Siddiqui Mr. Jan 2024

Dysbiosis In Parkinson's Disease: A Meta-Analysis Of Gut Microbiota And Its Role In Gastrointestinal Dysfunction And Disease Progression, Ayan M. Siddiqui Mr.

Honors Undergraduate Theses

Parkinson's Disease (PD) is a neurodegenerative disorder characterized by motor and nonmotor symptoms, including gastrointestinal (GI) dysfunction. Symptoms such as constipation, bloating, and nausea often show early signs before the onset of motor symptoms. Recent research has suggested an essential role of the human gut microbiome and gut dysbiosis, an imbalance in gut microbiota composition, in the pathogenesis of PD. This thesis aims to assess the potential relationship between gut dysbiosis and PD by conducting a meta-analysis, focusing on differences in gut microbiota between PD patients and healthy controls and evaluating their implications for GI dysfunction and PD progression. The …


Examination Of The Morphological Changes And Genotoxic Effects Of Sodium Benzoate On Neuro-2a Cells In Vitro, Emily S. Larson Jan 2024

Examination Of The Morphological Changes And Genotoxic Effects Of Sodium Benzoate On Neuro-2a Cells In Vitro, Emily S. Larson

Honors Undergraduate Theses

Sodium benzoate is a food preservative present in sodas, fruit juices, and other acidic foods and beverages [1]. Its acceptable daily intake is 0-20 mg/kg body weight [2], and it is generally recognized as safe [1, 3]. However, sodium benzoate has been linked to hyperactivity in children [4, 5] and adults [6] and to deficits and behavioral changes in rodents [7-10], indicating potential negative impacts on the nervous system. Sodium benzoate has also induced genotoxic effects in human lymphocytes [11, 12] and Chinese hamster fibroblast cells [13] in vitro and in rat liver tissue in vivo [14]. The effect of …


The Comparative Efficacy Of Ketamine And Esketamine In Treating Anhedonia And Suicidal Ideation: A Meta-Analysis, Yanyi Wu Jan 2024

The Comparative Efficacy Of Ketamine And Esketamine In Treating Anhedonia And Suicidal Ideation: A Meta-Analysis, Yanyi Wu

Honors Undergraduate Theses

This meta-analysis examines the efficacy and effectiveness of racemic ketamine (RS-ketamine) and esketamine in reducing depressive symptoms such as suicidal ideation and anhedonia in patients suffering from treatment-resistant depression and bipolar disorder. This review comprehensively looks at six studies: three clinical studies focusing on suicidal ideation and three looking at anhedonia. Across the studies, RS-ketamine and esketamine were associated with a higher resolution of suicidal ideation, risk, and anhedonia. Significant improvements were noted in the suicidal desire and ideation subscale of the Beck Scale for Suicidal Ideation. The pooled effect size for suicidal ideation (d = 0.533) and pooled …


Majorie In War And Peace, Gary R. Mormino Jan 2024

Majorie In War And Peace, Gary R. Mormino

The Marjorie Kinnan Rawlings Journal of Florida Literature

No abstract provided.


The Renaissance Of The Traphagen Farm, Ann Mccutchan Jan 2024

The Renaissance Of The Traphagen Farm, Ann Mccutchan

The Marjorie Kinnan Rawlings Journal of Florida Literature

No abstract provided.


Marjorie Kinnan Rawlings Writing Award Co-Winner Graduate Essay: "Douglas And Rawlings: Literary Awareness And Advocacy Of Florida Environment", Hind Berji Jan 2024

Marjorie Kinnan Rawlings Writing Award Co-Winner Graduate Essay: "Douglas And Rawlings: Literary Awareness And Advocacy Of Florida Environment", Hind Berji

The Marjorie Kinnan Rawlings Journal of Florida Literature

No abstract provided.


Marjorie Kinnan Rawlings Writing Award Co-Winner Graduate Essay: The Social Problems With Cross Creek's Transcendentalism, Mohammed Forero Bucheli Jan 2024

Marjorie Kinnan Rawlings Writing Award Co-Winner Graduate Essay: The Social Problems With Cross Creek's Transcendentalism, Mohammed Forero Bucheli

The Marjorie Kinnan Rawlings Journal of Florida Literature

No abstract provided.


An Assessment Of The Hotel Customers’ Robotic Service Quality Perceptions: Scale Development And Validation, Ahmet Hacikara Jan 2024

An Assessment Of The Hotel Customers’ Robotic Service Quality Perceptions: Scale Development And Validation, Ahmet Hacikara

Graduate Thesis and Dissertation 2023-2024

"Hotel customers' interactions with service robots are becoming increasingly common, raising questions about how these interactions impact their experience. To address this gap in knowledge, this dissertation develops and validates a novel robotic service quality (ROBOQUAL) scale. Drawing on social exchange theory, the study examines the reciprocal relationship between hotel customers and artificially intelligent service robots, exploring how robotic service quality influences customers' perceptions of experience quality, satisfaction, and word-of-mouth intentions. The research employs focus-group studies, exploratory factor analysis (EFA), confirmatory factor analysis (CFA), and partial least squares equation modeling (PLS-SEM) to develop and validate the ROBOQUAL scale."


An Examination Of Frontline Service Workers' Empathy In A Cobot Team, Emily Anne Broker Jan 2024

An Examination Of Frontline Service Workers' Empathy In A Cobot Team, Emily Anne Broker

Graduate Thesis and Dissertation 2023-2024

Service robots are an emerging technological advancement increasingly utilized in the hospitality industry. In return, service workers are required to use them during their interactions with customers. This study sought to examine how the service robot-worker team affects cognitive and affective empathy present in a service encounter. Using the empathy attribute part of the SERVQUAL model, this study aimed to examine and differentiate the server's empathy impact in the presence of a service robot. This study utilized semi-structured qualitative interviews to collect data from service workers employed in two restaurants characterized by distinct service environments. The interviews were qualitatively analyzed …


Identifying Antecedents And Consequences Of Mental Imagery: The Use Of Sor Theory In The Context Of Immersive Digital Exhibitions, Yeonjae Kim Jan 2024

Identifying Antecedents And Consequences Of Mental Imagery: The Use Of Sor Theory In The Context Of Immersive Digital Exhibitions, Yeonjae Kim

Graduate Thesis and Dissertation 2023-2024

With innovative technologies, various types of immersive digital experiences (IDEs) have gained significant attention in the past few years. Despite their popularity, little research has been conducted on the factors that examine visitors’ experiences and behavioral intentions. This study applies experience economy within the framework of the SOR (Stimulus-Organism-Response) theory, indicating the dimensions of IDE function as stimulus (S), mental imagery and attitude as the organism (O), and behavioral intentions as the response (R). This study aims to identify the antecedents and consequences of mental imagery to explain and understand the mechanism behind visitors’ evaluations for future decisions.

A total …


Development Of A Novel Mitochondria Biosensor, Randall K. James Jan 2024

Development Of A Novel Mitochondria Biosensor, Randall K. James

Graduate Thesis and Dissertation post-2024

Developing new label-free paradigms for functional assays in biomedical research has the potential to catalyze efforts in drug discovery and improve the understanding of complex disorders. Mitochondria are an essential organelle in nearly every eukaryotic organism that perform vital functions such as ATP production, redox signaling, reactive oxygen species (ROS) homeostasis and regulation of programmed cell death. These activities are regulated by electrophysiological processes that occur in the inner mitochondrial membrane (IMM) and outer mitochondrial membrane (OMM) in response to metabolic demands, making them an important physiological marker for bioenergetic studies. Mitochondria dysfunction is an early pathological biomarker of complex …


Flora And The Cloud Maker: Exploring Burnout Through Animation, Tiffany Marin Jan 2024

Flora And The Cloud Maker: Exploring Burnout Through Animation, Tiffany Marin

Graduate Thesis and Dissertation post-2024

Flora and The Cloud Maker is a two-dimensional (2D) animated short film inspired by my personal experiences as a graduate student learning to balance work-life demands. Pursuing higher education has generated many unanticipated challenges. One of these challenges includes experiencing the state of psychological exhaustion, or “burnout”. Flora and The Cloud Maker’s purpose is to show that burnout is common, and recovery is possible. Many graduate students struggle with work-life balance, burnout, and anxiety in their daily lives. Through strong use of color theory and charming visuals, Flora and The Cloud Maker demonstrates that though the road to higher education …


After A Tragedy: A Mobile Therapeutic Themed Experience, Sarah M. Massarelli Jan 2024

After A Tragedy: A Mobile Therapeutic Themed Experience, Sarah M. Massarelli

Graduate Thesis and Dissertation post-2024

The purpose of this thesis is to design a mobile therapeutic-themed experience that will help start the healing process for victims, direct and indirect, after a mass shooting incident. This design will attempt to address the stigma around seeking traditional mental health care and try to create opportunities for victims, direct and indirect, to support another even though they may not want to seek help from a therapist. Not every victim will react to the mass shooting incident in the same way, and not every person processes their feelings and emotions in the same way. The experience is designed to …


Sars-Cov-2 Infection History Is Positively Correlated With Frequency Of Psychotic Symptoms In Schizophrenia, Jackson D. Beecher Jan 2024

Sars-Cov-2 Infection History Is Positively Correlated With Frequency Of Psychotic Symptoms In Schizophrenia, Jackson D. Beecher

Honors Undergraduate Theses

Previous work in human and animal studies has implicated aberrant insular cortex (IC) activity in the pathophysiology of hallucinations. Of note, the IC overlaps with the olfactory cortex (OC), a region of the brain that receives extensive projections from sensory neurons of the olfactory epithelium. SARS-CoV-2 (COVID-19) is a highly infectious coronavirus with a demonstrated ability to cause anosmia; the virus does this by colocalizing with and damaging support cells in the olfactory epithelium, ultimately leading to alterations in olfactory receptor cell signaling to the OC. Given the overlap between OC and IC, we asked the question of whether COVID-19 …


Exploring Filipino Restaurants In Greater Orlando, Jeremy Quinn T. Braga Jan 2024

Exploring Filipino Restaurants In Greater Orlando, Jeremy Quinn T. Braga

Honors Undergraduate Theses

This ethnographic study examines how Filipino restaurants in Greater Orlando leverage traditional foodways and interior design to gain and sustain customer followings. Data elicitation techniques such as participant observation, semi-structured interviews, photography, and mapping help build a general portrait of these niche out-to-eat venues in central Florida. Collected findings suggest that Filipino restaurants in Greater Orlando are extremely varied from the type of eatery they are, the mode of consumption and their interior design choices. Dine-in, takeout from turo-turo stores, or fast food are the many ways one can get food. Most of the time the interior design of the …


Elements Of The Criminal Mind, Kelsie A. Esposito Ms. Jan 2024

Elements Of The Criminal Mind, Kelsie A. Esposito Ms.

Honors Undergraduate Theses

Studying human behavior and societal dynamics has captivated scholars across time. From ancient philosophers like Plato to contemporary researchers, the quest to comprehend our distinctiveness and the mechanisms that enable harmonious coexistence remains paramount. This thesis examines the enigmatic realm of the “criminal class,” looking at their identity and actions and the cognitive processes underpinning their behavior. Focusing on violent criminal offenders, this thesis seeks to provide greater meaning and understanding of the criminal mind.


Lifes Amazing When La'ing, George T. Rolle Iii Jan 2024

Lifes Amazing When La'ing, George T. Rolle Iii

High Impact Practices Student Showcase Spring 2024

A young college student who fears chemistry is offered the chance to assist in teaching the course he once dreaded. This is their story of overcoming the obstacles faced in not only understanding the course but knowing how to prepare for it as well. Throughout his spring semester, he will learn the ins and outs and eventually create a way to educate others.


Unraveling Molar Wear Patterns Of San Pedro Maya: Exploring Dietary Correlations And Oral Health, Julie M. Alvarez, Emily Boutin Jan 2024

Unraveling Molar Wear Patterns Of San Pedro Maya: Exploring Dietary Correlations And Oral Health, Julie M. Alvarez, Emily Boutin

High Impact Practices Student Showcase Spring 2024

This study investigates the oral health and dietary practices of the historical San Pedro Maya population in Belize. By analyzing the wear patterns on their molars, we gained insights into their past diet and oral health conditions. The findings contribute to a deeper understanding of the lifestyle and health of the San Pedro Maya in ancient times. This research illuminates the connections between diet and oral health among this indigenous group, offering valuable historical insights into their well-being and contributing to our understanding of ancient Maya civilization. We hope to add to what is known about the Maya of San …


Beyond Fear: Inspiring Students To Appreciate Sharks And Understand Their Role In The Ocean, Carolina A. Souza, Janelle Seefelt, Jordyn Delikat, Brianna Rendon Jan 2024

Beyond Fear: Inspiring Students To Appreciate Sharks And Understand Their Role In The Ocean, Carolina A. Souza, Janelle Seefelt, Jordyn Delikat, Brianna Rendon

High Impact Practices Student Showcase Fall 2024

Our team visited a fourth-grade classroom of 26 students at Geneva Elementary School to speak on sharks. We highlighted the ecological significance of sharks, cultural respect for them in Polynesian and Hawaiian cultures, threats facing shark populations, and different ways students could help protect them. Our goal was to address negative stigma surrounding sharks. The students participated in a take-home project where they decorated their own paper bag shark puppet and wrote what they loved about sharks on the back. They also made shark tooth necklaces. Lastly, each student picked a marine organism, decorated it, and glued it onto a …


Waves Of Influence- Our Impact On The Next Generation, Caleb Ryland, Mariam Sonbol, Joedy Maysonet, Lea Obendorf Jan 2024

Waves Of Influence- Our Impact On The Next Generation, Caleb Ryland, Mariam Sonbol, Joedy Maysonet, Lea Obendorf

High Impact Practices Student Showcase Fall 2024

Through our Service-Learning experience, the four of us came together to create a meaningful learning opportunity for a class of grade school students while also contributing to marine conservation. Our goal was to teach them about the unique adaptations of marine life, focusing on concepts like bioluminescence and camouflage. To make the lesson engaging, the students crafted glow-in-the-dark jellyfish to represent bioluminescence and colored cutouts to demonstrate camouflage. By tapping into their creativity, they not only learned but also showcased their newfound knowledge. The success of our efforts was reflected in the students' improved scores on a post-test compared to …


Disability Representation In Contemporary Playwriting, Caroline Hull Jan 2024

Disability Representation In Contemporary Playwriting, Caroline Hull

Graduate Thesis and Dissertation 2023-2024

Is it possible for a playwright to authentically capture the disabled experience without it becoming privy to stereotypes or utilized as a catalyst for the plot? The thesis aims to challenge the prevalent notion that making the disability intrinsic to a theatrical plot is essential for authentic representation, and instead asserts that authentic portrayal of the disabled experience can exist independently of making the disability a central plot device. To support this claim, In Chapter One, I engage with relevant work in the field of playwriting and narrative media studies, such as the workshop "Inaccessible: Writing Plays with Characters who …


Steps Of Theatrical Design: A Resource For Activating Educators To Teach Design In High Schools, Chandler Caroccio Jan 2024

Steps Of Theatrical Design: A Resource For Activating Educators To Teach Design In High Schools, Chandler Caroccio

Graduate Thesis and Dissertation 2023-2024

As a designer and educator, I am continuously gathering more resources for personal knowledge and to share with my students. Yet there is currently a lack of literature when it comes to design pedagogy for all design areas, specifically for high school aged students. How can we teach theatrical design in a tactful and meaningful way to high school students throughout the United States? Steps of Theatrical Design: A Resource for Activating Educators to Teach Design in High Schools, is for educators to learn about the process of design and spread that knowledge to their students. This thesis will …


The Boyfriend Dungeon Controversy: Fan Labor And Toxic Fan Practices In Progressive Fandom, Angela Orozco Jan 2024

The Boyfriend Dungeon Controversy: Fan Labor And Toxic Fan Practices In Progressive Fandom, Angela Orozco

Graduate Thesis and Dissertation 2023-2024

On August 11, 2021, the hack and slash video game and queer dating simulator, Boyfriend Dungeon, was released to play on PC and various gaming consoles by indie developer, Kitfox Games. Quickly upon its release, the development team was met with fan outrage regarding a misleading content warning and themes that were not mentioned during the game's fundraising stage. This culminated in an online harassment campaign against Kitfox Games, with many fans targeting the voice actor of the game's main villain.

The following study attempts to analyze some of the core elements of what is now known to online …


In Vitro Metabolite Identification Of Indole 3-Ylcycloalkyl Ketones, Inez M. Jacobs-Hinton Jan 2024

In Vitro Metabolite Identification Of Indole 3-Ylcycloalkyl Ketones, Inez M. Jacobs-Hinton

Graduate Thesis and Dissertation post-2024

Synthetic cannabinoids (SCs) have emerged as a complex and evolving class of compounds designed to mimic the effects of natural cannabinoids, targeting the endocannabinoid system. Despite their widespread recreational use and therapeutic potential, the safety and pharmacokinetic properties of synthetic cannabinoids remain inadequately understood. This study examines the in vitro drug metabolism of a prominent class of SCs—indole-3-ylcycloalkyl ketones—by identifying and characterizing their metabolites. Human liver microsomes were used to investigate the metabolism of several SCs, including (2,2,3,3-tetramethylcyclopropyl)[1-(4,4,4-trifluorobutyl)-1H-indol-3-yl]-methanone (XLR-12), 1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl-methanone (A-796260), 1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl-methanone (AB-005), 1-(5-fluoropentyl)-1H-indazol-3-yl-methanone (FAB-144), and 1-[(tetrahydro-2H-pyran-4-yl)methyl]-1H-indol-3-yl-methanone (A-834735). Several time points were chosen to assist in elucidating the dynamics of …


A Quantitative Approach To The Analysis Of Human Hair For Forensic Examinations, David S. Hernandez Funes Jan 2024

A Quantitative Approach To The Analysis Of Human Hair For Forensic Examinations, David S. Hernandez Funes

Graduate Thesis and Dissertation post-2024

Hair is frequent trace evidence found in crime scenes due to its high transfer potential due to natural shed. They can provide investigative information in various cases, including homicide, sexual assault, missing persons, and human trafficking. Physical examination of hair involves the analysis of microscopic features, such as color and pigmentation, commonly using bright field microscopy. Microscopical techniques are non-destructive, with minimum to no sample preparation that can be followed by chemical and biological analysis. Although individualization is not possible via microscopical methods, it can be used to include or exclude potential donors. However, previous microscopical techniques lack quantitative and …


Assessment Of Caretaker Resources And Motivation In The Wean-To-Market Phase Of Swine Production, Joshua W. Holtkamp Jan 2024

Assessment Of Caretaker Resources And Motivation In The Wean-To-Market Phase Of Swine Production, Joshua W. Holtkamp

Graduate Thesis and Dissertation 2023-2024

This study is a novel application of I/O Psychology principles to the U.S. swine industry. The Swine Health Information Center (SHIC) recently identified caretaker motivation related to compliance with biosecurity behaviors as a priority needing to be better understood. This exploratory study seeks to identify if there is indeed a worker motivation issue within the industry that is impacting compliance with biosecurity, and if so, establish both a baseline of motivation and a better understanding of the primary influencing factors. Using the Theory of Planned Behavior and the Job Demands/Resources Model of Burnout as a framework, an online survey was …


Exploring Barriers And Pathways To Public Engagement On Climate Change, Monica Mayer Jan 2024

Exploring Barriers And Pathways To Public Engagement On Climate Change, Monica Mayer

Graduate Thesis and Dissertation post-2024

Despite evidence of its severity and urgency, climate change elicits relatively high skepticism and low concern within the U.S. This study explores psychological barriers preventing people from prioritizing the issue as well as potential strategies to overcome those barriers. Interviews with individuals living in Florida identifying as cautious, disengaged, or doubtful about climate change were conducted between September and October 2023. Participants expressed skepticism over humanity’s impact on the climate. They further conveyed that other nations have a larger impact on climate change than the U.S, that the issue’s criticality is exaggerated, and that observable weather shifts are not the …


Humor As An Instructional Communication Tool: Revisiting Humor And Exploring The New Punchline In Human-Machine Communication, Melissa M. Looney Jan 2024

Humor As An Instructional Communication Tool: Revisiting Humor And Exploring The New Punchline In Human-Machine Communication, Melissa M. Looney

Graduate Thesis and Dissertation post-2024

This research examined the role of humor in instructional communication, focusing on human-to-human and human-machine communication (HMC). As artificial intelligence (AI) becomes increasingly embedded in learning environments, it is critical to understand how elements such as humor influence user perceptions and, consequently, affective learning outcomes. Previous arguments about humor in educational settings, particularly those centered on traditional student-teacher interactions, have been arguably derelict. Therefore, this research revisited earlier assertions about humor, extending the inquiry to include online communication and AI-driven chatbots in learning management systems. Specifically, the study explored how humor and the type of agent (human or AI chatbot) …


Competing Narratives And Converging Perspectives: Analyzing The Dynamics Of The Pulse Memorial Crisis, Amy E. Maciel Jan 2024

Competing Narratives And Converging Perspectives: Analyzing The Dynamics Of The Pulse Memorial Crisis, Amy E. Maciel

Graduate Thesis and Dissertation 2023-2024

In the wake of the Pulse nightclub massacre, the effort to create a memorial devolved into a crisis and ultimate failure amidst a complex interplay of divergent claims. This study explored the evolving memorialization process for the creation of a Pulse Memorial, utilizing Fisher's narrative paradigm to analyze articles from the Orlando Sentinel published between January 1st, 2023, and January 31st, 2024. By employing Fisher's framework, which emphasizes narrative fidelity and narrative probability, this study investigated the dynamic evolution of storytelling related to the Pulse Memorial Crisis. Through thematic analysis, the study explored how stakeholders constructed and challenged the memory …


Handheld X-Ray Fluorescence (Hhxrf) As A Non-Destructive Method For Trace Element Analysis Of Ancient Maya (Pre-Conquest 800 Bc - Ad950) Teeth From Altun Ha, Belize, Griffon G. Binkowski Jan 2024

Handheld X-Ray Fluorescence (Hhxrf) As A Non-Destructive Method For Trace Element Analysis Of Ancient Maya (Pre-Conquest 800 Bc - Ad950) Teeth From Altun Ha, Belize, Griffon G. Binkowski

Honors Undergraduate Theses

In anthropology, elemental analysis of bone and teeth can provide significant details about an individual’s life history, such as diet, toxicity exposure, residency, and migration patterns. Intra-individual comparisons can help to gather information about a single individual’s life, while inter-individual comparisons can help illustrate a community’s life history during these periods. However, current methods of elemental analysis commonly involve the destruction of skeletal samples, which can damage a collection’s integrity and be perceived as disrespectful by descendant communities. Preliminary research has validated handheld x-ray fluorescence spectrometry (HHXRF) as an accurate and reliable method of analysis appropriate for determining the elemental …