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Articles 2881 - 2910 of 6994
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Gold (Iii) Macrocycles Are Dna Intercalators That Inhibit Topoisomerase I And Ii, Alexander Fagenson
Gold (Iii) Macrocycles Are Dna Intercalators That Inhibit Topoisomerase I And Ii, Alexander Fagenson
HIM 1990-2015
Human Topoisomerase IB (TOP1) and Topoisomerase II? (TOP2?) are essential nuclear enzymes that control DNA topology during DNA replication, gene transcription and cell division. These enzymes carry out their catalytic function by making transient single-strand (type I) or double-strand (type II) breaks in the DNA. In vivo, these complexes are short-lived but can be exploited by anti-cancer drugs to mechanistically kill cancer cells. Two general classes of compounds can kill cancer cells through a topo-targeted mechanism. Interfacial Poisons (IFPs) act at the enzyme-DNA interface to inhibit the religation reaction, resulting in the accumulation of DNA double-stand breaks (DSBs) in the …
Savage In Limbo A Study In Lighting Design, Kenneth Haines
Savage In Limbo A Study In Lighting Design, Kenneth Haines
HIM 1990-2015
Designing the elements of a theatrical production is a unique and often experimental process. This process changes from show to show, and it can be difficult for a viewer to differentiate mistakes from design choices without a background in lighting. That is why it is important to take a look at the design process step by step. Two goals I strove for when designing Savage In Limbo were, how the director's concept blended with a design and if the integrity of the designer's vision was evident on stage. To explore these goals, script analysis and consideration of the director's vision …
An Exploratory Factor Analysis Of Self-Reported State And Trait Guilt, Christina Lacerenza
An Exploratory Factor Analysis Of Self-Reported State And Trait Guilt, Christina Lacerenza
HIM 1990-2015
The construct of guilt has been a subject of debate among philosophers, theologians, sociologists and psychologists for centuries. Disagreements concerning guilt have emerged on the definitional level, measurement level, and conceptual level due to the various ways guilt can be experienced and interpreted. Researchers continue to empirically investigate various aspects of guilt in an effort to advance and refine our understanding of the construct; however, differences among researchers in assessing the impact of guilt on psychological well-being still exist. The purpose of this study is to investigate the internal factor structure of three prominent measures of guilt. This will enable …
Determination Of The Biological Sex Of Juveniles Based Upon The Odontometrics Of The Primary Dentition, Kendall Mccollough
Determination Of The Biological Sex Of Juveniles Based Upon The Odontometrics Of The Primary Dentition, Kendall Mccollough
HIM 1990-2015
Sex determination in human skeletal remains is difficult under the most ideal circumstances; however, in juvenile skeletal remains it is nearly impossible. Currently no accepted techniques exist to identify the biological sex of the juvenile skeleton, other than, when possible, DNA. Thus, developing an accessible and non-destructive technique would benefit both the field of Forensic Anthropology and Bioarchaeology. The ability to provide a quick and accurate determination of sex would greatly expedite the identification process in any case where juvenile skeletal remains are involved. This project aims to establish an accessible and non-destructive method for determining the sex of juvenile …
Determination Of The Hydrogen Peroxide Concentration In Rotenone Induced Dopaminergic Cells Using Cyclic Voltammetry And Amplex Red, Kishan Patel
HIM 1990-2015
Parkinson's disease (PD) is a neurodegenerative condition that affects millions of people worldwide. The exact etiology of PD is unknown. However, it is well established that environmental factors contribute to the onset of PD. In particular, chemicals such as the insecticide Rotenone have been shown to increase the death of dopaminergic (DA) neurons by increasing levels of reactive oxygen species (ROS). ROS such as hydrogen peroxide (H2O2) have been shown to be elevated above basal levels in PD patients. Currently, to measure H2O2 concentrations, a commercially available (Amplex® Red) fluorescent assay is used. However, the assay has limitations: it is …
Resurrecting Inanna: Lament, Gender, Transgression, Kimberly Torres
Resurrecting Inanna: Lament, Gender, Transgression, Kimberly Torres
HIM 1990-2015
This essay, which is at once a literary critical examination and a theological exploration of the Hebraic scriptural book of Lamentations in relation to ancient Sumerian lament, employs a mixed critical approach (e.g., form, feminist, postmodern, reader response), to address various lyrical, contextual, and thematic elements common to both the biblical Lamentations and the older Sumerian compositions. Specific focus is given to issues of gender and gender-malleability, as well as the notion of "transgression" and the various meanings that may be attached to this word in various contexts, theological or otherwise. Also addressed is the means by which the lament …
Cognitive Theory A Qualitative Comparison Of The George W. Bush Administration And The Barack H.Obama Administration, Shelley Urbanovich
Cognitive Theory A Qualitative Comparison Of The George W. Bush Administration And The Barack H.Obama Administration, Shelley Urbanovich
HIM 1990-2015
Although Republicans and Democrats frequently disagree ideologically, the leaders of both parties share one commonality in particular--they inevitably make flawed judgments. To adequately understand the extent to which psychological filters act as a fundamental factor in decision making, this thesis shall analyze current political events and observe how partisans within both administrations deal with information incompatible with their own values and beliefs. Specifically referencing the war in Iraq, weapons of mass destruction (WMDs), civil unrest, national security, the national economic climate, and the housing market, this study examines the way leaders deal differently with conflicting information. Although all subjects in …
The Duality Of Florida's Criminal Pretrial Diversion Programs A Separate Treatment Court For Veterans, David Vanzandt
The Duality Of Florida's Criminal Pretrial Diversion Programs A Separate Treatment Court For Veterans, David Vanzandt
HIM 1990-2015
This thesis examines two issues facing Florida's young and fledgling Veteran Treatment Courts. First is whether or not a separate hybrid court of already existing mental health and drug courts is needed exclusively for veterans; and second, funding and efficiency of such courts as compared to traditional criminal institutions.
A Contact Analysis Of Caldecott Medal And Honor Books From 2001-2011 Examining Gender Issues And Equity In 21st Century Children's Picture Books, Nicole Yello
HIM 1990-2015
An abundance of research has been conducted about the importance of including books and literature as part of a young child's developmental process. Much of this research suggests that picture books are vital to a young child's healthy development and "are important influences that shape us by reflecting the politics and values of our society" (Fox, 1993, p. 656). This study was completed to analyze character roles and gender representation of male and female characters exclusively in children's picture books. The entire population of Caldecott Award and Honor Medal books published between 2001 and 2011 was utilized for a frequency …
The Pastel Medium Communicating Sexuality And Promiscuity In Late Nineteenth-Century Paris, Adee S. Benartzy
The Pastel Medium Communicating Sexuality And Promiscuity In Late Nineteenth-Century Paris, Adee S. Benartzy
HIM 1990-2015
Throughout the history of art, the pastel medium has been considered a medium of secondary interest. Despite its pulsating textures, vibrant colors, and unique receptivity to touch, this medium has been recognized above all for its swiftness in stroke and subsequent ability of the artist to record images of fleeting moments and ideas almost instantaneously. The focus on the advantageous rapidity of the pastel, however, hindered the pastel medium's potential as a mere preliminary technique to working with grander mediums, such as oil paint, thus failing to recognize the prominence of pastel in capturing character. This research endeavor focuses on …
The Nature Of Love A Phenomenological Approach, Samantha Schroeder
The Nature Of Love A Phenomenological Approach, Samantha Schroeder
HIM 1990-2015
As I hope to show, a philosophical study of love is highly relevant today, since the sciences have not adequately answered the perennial question: What is love?; Since the time of Socrates, the idea of love and the conception of the human heart have been devalued by thinkers who, by definition, are known as "lovers of wisdom." Considered pejoratively as "the passions," the subject of emotion was deemed inferior to thought centered upon the human faculty of reason. Many studies in the sciences, from biology to psychology, claim to have pointed us to the source of the human experience of …
Identification Of Spatiotemporal Nutrient Patterns And Associated Ecohydrological Trends In The Tampa Bay Coastal Region, Brent Wimberly
Identification Of Spatiotemporal Nutrient Patterns And Associated Ecohydrological Trends In The Tampa Bay Coastal Region, Brent Wimberly
HIM 1990-2015
Improvements for environmental monitoring and assessment were achieved to advance our understanding of sea-land interactions and nutrient cycling in a coastal bay.; The comprehensive assessment techniques for monitoring of water quality of a coastal bay can be diversified via an extensive investigation of the spatiotemporal nutrient patterns and the associated eco-hydrological trends in a coastal urban region. With this work, it is intended to thoroughly investigate the spatiotemporal nutrient patterns and associated eco-hydrological trends via a two part inquiry of the watershed and its adjacent coastal bay. The findings show that the onset of drought lags the crest of the …
And It's Also The Smell Of Laundry, Rachel Miranda
And It's Also The Smell Of Laundry, Rachel Miranda
HIM 1990-2015
This collection of poems brings to life the idea that in a poet's world, every day life and every single occurrence is a possible subject. Included are works brought on from the worst of circumstances, the youngest of memories, the happiest moments, and even the simplest of thoughts. The collection is autobiographical and reflective, a re-creation of the events taken place with the addition of present knowledge. The work here gives proof to the idea of cohesion between content and art form--it proves the notion that how something is being said is just as, if not more, important than what …
University Of Central Florida Undergraduate Catalog, 2012 - 2013, University Of Central Florida
University Of Central Florida Undergraduate Catalog, 2012 - 2013, University Of Central Florida
UCF Catalogs
No abstract provided.
Towards The Finite A Case Against Infinity In Jorge Luis Borges, Esteban Santis
Towards The Finite A Case Against Infinity In Jorge Luis Borges, Esteban Santis
HIM 1990-2015
The role of infinity as an antagonist in Jorge Luis Borges's oeuvre is undeniable. His stories in El jardiÂn de senderos que se bifurcan (1941), Ficciones (1944), and El Aleph (1949) exhibit Borges's tendency to evoke dreams, labyrinths, mirrors, and libraries as both conduits for infinity and sources of conflict. Oftentimes, Borges's characters experience discomfort upon encountering the limitations of secular temporal succession. This discomfort is rooted in Borges's pessimism about the subject which is explored in Borges's most comprehensive essay on the issue of time: "A New Refutation of Time." Consequently, this thesis considers Borges's attitude towards the issue …
Examining Crowd Violence Connected To Sport Applying The Hooligan Template, Kelly Worthen
Examining Crowd Violence Connected To Sport Applying The Hooligan Template, Kelly Worthen
HIM 1990-2015
The aim of the research is to evaluate crowd violence as it pertains to sports and its spectators. In particular, the research examines sports riots. "A sports riot is defined as violence-vandalism, throwing/shooting missiles, rushing the field or court, committing arson, and/or fighting- committed by five or more individuals in a crowd of one hundred people associated with a formally organized sporting event" (Lewis, 2007). On a micro level, the most prevalent form of spectator violence is the act of Hooliganism in relation to football (soccer). The research on this aggression has been primarily inherent in Europe and South and …
Sandspur, Vol 118, No 15, April 26, 2012, Rollins College
Sandspur, Vol 118, No 15, April 26, 2012, Rollins College
The Rollins Sandspur
Rollins College student newspaper, written by the students and published at Rollins College. The Sandspur started as a literary journal.
Sandspur, Vol 118, No 13, March 29, 2012 (April Fools' Edition), Rollins College
Sandspur, Vol 118, No 13, March 29, 2012 (April Fools' Edition), Rollins College
The Rollins Sandspur
Rollins College student newspaper, written by the students and published at Rollins College. The Sandspur started as a literary journal.
Sandspur, Vol 118, No 12, March 15, 2012, Rollins College
Sandspur, Vol 118, No 12, March 15, 2012, Rollins College
The Rollins Sandspur
Rollins College student newspaper, written by the students and published at Rollins College. The Sandspur started as a literary journal.
Sandspur, Vol 118, No 11, February 23, 2012, Rollins College
Sandspur, Vol 118, No 11, February 23, 2012, Rollins College
The Rollins Sandspur
Rollins College student newspaper, written by the students and published at Rollins College. The Sandspur started as a literary journal.
Methods For Modifying Stem Cell Characteristics, Kiminobu Sugaya, Angel Alvarez
Methods For Modifying Stem Cell Characteristics, Kiminobu Sugaya, Angel Alvarez
UCF Patents
We propose a method of expanding stem cells and dedifferentiating cells by cultruing cells with cell cultrue extracts of embryonic stem cellas and or extracts from a regenerating limb. We demonstrated that co cultureing human bone marrow mesenchymal stem cells with sections of a lizard tail or mouse embryonic stem cells increases the stemness of the Msc. This allows for the creation of a cell cultruing system containing expgenous factors that facilitate increased expression of stem cells genes and dedifferentiation.
On Site Wastewater Treatment Using A Functionalized Green Filtration Media Sorption Field (Divb), Ni-Bin Chang, Ammarin Makkeasorn
On Site Wastewater Treatment Using A Functionalized Green Filtration Media Sorption Field (Divb), Ni-Bin Chang, Ammarin Makkeasorn
UCF Patents
Methods, systems and compositions for a green sorption media for bioretention soil amendments in drainfields for on-site waste water systems filled with the green sorption media to foster an anaerobic or anoxic environment saturated. The green sorption media includes one or more recycled materials, including tire crumb, sawdust, orange peel, coconut husks, leaf compost, oyster shell, soy bean hulls and one or more naturally occuring materials including peat, sands, zeolites, and clay. The wastewater filtration system for a passive drainfield includes the green sorption material mixture, a cell including baffled compartments and a riser, the cell filled with green sorption …
Dubious Role Of Mycobacterium Paratuberculosis In Pathogenesis Of Type I Diabetes, Saisathya Thanigachalam
Dubious Role Of Mycobacterium Paratuberculosis In Pathogenesis Of Type I Diabetes, Saisathya Thanigachalam
Electronic Theses and Dissertations
Background: Type 1 Diabetes mellitus (TIDM) is a chronic disorder in which the insulin producing beta cells are selectively self-destroyed. Although the etiology of the disease has not been determined, genetic dispositions such as SLC11A1 polymorphism in suffering patients have been reported. The role of pathogenic microorganisms such as Mycobacterium avium subspecies paratuberculosis (MAP) in TIDM has also been recently debated. MAP is already known to cause paratuberculosis in cattle and now it is a strong suspect of causing autoimmune diseases in humans such as Crohn’s disease, multiple sclerosis, autoimmune Thyroiditis, rheumatoid arthritis and autoimmune diabetes. We hypothesis that molecular …
Cross-Sector And Inter-Organizational Collaborative Capacity In Community Disaster Resilience And Sustainability: Evidence From Central Florida Counties, Fatih Demiroz
Electronic Theses and Dissertations
This study examines the relationships between interorganizational network development and sustainability, organizational capacity for emergency management, technology utilization, and community disaster resiliency. It is proposed that cross sector and interorganizational collaboration (i.e., network development and sustainability), information communication technology (ICT) utilization, and organizational capacity have a positive impact on disaster resiliency. Disaster resiliency is measured with a three dimensional metric which includes effectiveness of disaster response, effectiveness of disaster recovery, and adaptive capacities. A questionnaire was sent to organizations that are part of the emergency management system in 11 counties in Central Florida. These organizations were identified by each county's …
Transplantation Of Pluripotent Stem Cells Confers Cardiac Protection In Dox-Induced Heart Failure Through Notch-1 Pathway, Hilda Merino-Chavez
Transplantation Of Pluripotent Stem Cells Confers Cardiac Protection In Dox-Induced Heart Failure Through Notch-1 Pathway, Hilda Merino-Chavez
Electronic Theses and Dissertations
Doxorubicin (DOX) is the antineoplastic drug of preference used to treat a wide variety of malignancies, with high survival rates among treated patients. However, the benefits of this drug have become less appealing due to the side effects that occur such as DOX-induced cardiomyopathy (DIC) and an increased risk of myocardial infarction (MI). Therefore, there is an urgent need to explore the therapeutic options to treat DIC. In this context, adult stem cells have been used as a source to reduce cardiomyocyte apoptosis in DIC; however, the effects of transplanted embryonic stem (ES) cells and induced pluripotent stem (iPS) cells …
The Gender Gap In Technical Communication: How Women Challenge The Predominant Objectivist Paradigm, Nathan Bower
The Gender Gap In Technical Communication: How Women Challenge The Predominant Objectivist Paradigm, Nathan Bower
Electronic Theses and Dissertations
Women are currently underrepresented in the Science, Technology, Engineering, and Mathematics (STEM) fields. The purpose of this thesis is to explore how this underrepresentation translates to a gender gap in the field of technical communication and how this gap causes women to challenge the predominant objectivist paradigm in the field. Through an investigation of peer-reviewed journal articles, periodicals, critical theory, and articles published in online magazines such as Slate, I identify the gendered nature of modern technology and discuss to what extent a shift in the predominant paradigm has occurred in the professional arena. In looking at several theoretical approaches …
Limk1 Promotes Mt1-Mmp Expression And Localization To The Plasma Membrane, Richard Ottman
Limk1 Promotes Mt1-Mmp Expression And Localization To The Plasma Membrane, Richard Ottman
Electronic Theses and Dissertations
LIM Kinase 1 (LIMK1), a serine/threonine kinase, modulates actin polymerization and microtubule assembly. The function of LIMK1 is regulated by kinases that are activated by Rho and Rac GTPases. LIMK1 is overexpressed in various cancerous cell types and tissues and its overexpression promotes increased invasion and metastasis of breast and prostate cancer cells. Membrane-Type Matrix Metalloproteinase 1 (MT1-MMP) is a member of the zinc-binding collagenase family, which is involved in extracellular matrix breakdown and activation of secreted MMP-2. The balance between activation and inhibition of MT1- MMP and MMP-2 helps maintaining normal extracellular matrix turnover. However, it has been shown …
Hunting For Bear: Tales Of Teddy Roosevelt, William Faulkner, And Marjorie Kinnan Rawlings, Leslie Kemp Poole
Hunting For Bear: Tales Of Teddy Roosevelt, William Faulkner, And Marjorie Kinnan Rawlings, Leslie Kemp Poole
The Marjorie Kinnan Rawlings Journal of Florida Literature
No abstract provided.
A Letter And A Dream: The Literary Friendship Of Ellen Glasgow And Marjorie Kinnan Rawlings, Ashley Lear
A Letter And A Dream: The Literary Friendship Of Ellen Glasgow And Marjorie Kinnan Rawlings, Ashley Lear
The Marjorie Kinnan Rawlings Journal of Florida Literature
No abstract provided.
An Alaskan Writer Learns About The Writing Life From Marjorie Kinnan Rawlings, Heather Lende
An Alaskan Writer Learns About The Writing Life From Marjorie Kinnan Rawlings, Heather Lende
The Marjorie Kinnan Rawlings Journal of Florida Literature
No abstract provided.