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Investigation Of Lubricin-Stimulating Fda-Approved Compounds For A Disease-Modifying Osteoarthritic Drug, Swathi S. Menon Jan 2025

Investigation Of Lubricin-Stimulating Fda-Approved Compounds For A Disease-Modifying Osteoarthritic Drug, Swathi S. Menon

Honors Undergraduate Theses

Osteoarthritis (OA) is a degenerative disease that affects many people worldwide. Current methods of treatment are palliative, and no treatment exists to fully reverse or cure OA once it begins to progress. The discovery of a disease-modifying osteoarthritic drug (DMOAD) would increase the quality of life for millions and reduce the need for invasive procedures. Screening FDA-approved drugs ensures more promise due to their known safety profile and potential for faster translation to the clinic. The goal of this project was to conduct dose-response assays with FDA-approved drugs that have been shown to stimulate lubricin production in cells that mimic …


Development Of A Proposed Selective Medium For The Isolation And Differentiation Of P. Sordellii, Dimyana Bottros Jan 2025

Development Of A Proposed Selective Medium For The Isolation And Differentiation Of P. Sordellii, Dimyana Bottros

Honors Undergraduate Theses

Clostridium, a genus of anaerobic, spore-forming bacteria, includes clinically and ecologically significant species like Clostridium difficile and Paeniclostridium sordellii. C. difficile causes antibiotic-associated colitis, while P. sordellii is linked to fatal infections and spontaneous abortions. Recent studies found both species in marine sediments, suggesting their role in environmental and wildlife health disturbances, including the 2013 mass mortality of over 300 manatees in the Indian River Lagoon. However, isolating and differentiating P. sordellii is challenging due to the lack of selective media optimized for its growth. This thesis proposes a novel selective medium tailored to P. sordellii’s physiological …


From Novel To Movie: The Yearling In Florida, Donna Green-Townsend, Kathlyne Walkup Sheppard Jan 2025

From Novel To Movie: The Yearling In Florida, Donna Green-Townsend, Kathlyne Walkup Sheppard

The Marjorie Kinnan Rawlings Journal of Florida Literature

No abstract provided.


Mabel Norris Reese: A Courageous Journalist's Pursuit Of Justice In Jim Crow Florida, Joy Wallace Dickinson Jan 2025

Mabel Norris Reese: A Courageous Journalist's Pursuit Of Justice In Jim Crow Florida, Joy Wallace Dickinson

The Marjorie Kinnan Rawlings Journal of Florida Literature

No abstract provided.


Introduction To Hurston's And Sexton's Letters, Marvin E. Hobson Jan 2025

Introduction To Hurston's And Sexton's Letters, Marvin E. Hobson

The Marjorie Kinnan Rawlings Journal of Florida Literature

No abstract provided.


Learning Dissemination Strategies: Lessons From The Covid-19 Pandemic In Training Healthcare Professionals In Disease Management, Kishan Vishanagra Jan 2025

Learning Dissemination Strategies: Lessons From The Covid-19 Pandemic In Training Healthcare Professionals In Disease Management, Kishan Vishanagra

Honors Undergraduate Theses

The COVID-19 pandemic presented many challenges for global healthcare systems, requiring rapid training and dissemination of disease management strategies among healthcare professionals. This study conducts a systematic review of 37 studies to examine the learning dissemination methods created and utilized during the COVID-19 pandemic, focusing on just-in-time training for disease management. This study identifies four core training topics: airway management, infection control, cardiopulmonary resuscitation, and patient triage. This study also categorizes delivery methods into in-situ simulation-based training, online e-learning platforms, online simulation-based training, and hybrid training models. Findings highlight that simulation-based training methods proved effective for invasive high-risk procedures, while …


Reconciling Theory And Praxis. Defending Subjective Agency Against Althusser's Structuralism - Daniel Guerrero, Daniel Guerrero Jan 2025

Reconciling Theory And Praxis. Defending Subjective Agency Against Althusser's Structuralism - Daniel Guerrero, Daniel Guerrero

Honors Undergraduate Theses

Louis Althusser labels Marx’s early works as humanist, pseudo-materialist, and self-contained within the ideology of German idealism. Therefore, all attempts to develop a Marxist theory based on these works are futile and ideological. Instead, Althusser proposes a ‘scientific’ reading of Marx developing a structuralist theory based on dialectical materialism. I argue that his interpretations deny individual agency and reduce social relations to mechanistic processes, which directly conflicts with fundamental Marxist ideas like alienation, production, and species-being. By discussing authors within the Marxist Humanist tradition, I argue that a theoretical framework based on Marx’s early works is not only possible, but …


My Service-Learning Experience, Conserving And Restoring Canaveral National Seashore, Thomas Cole Jan 2025

My Service-Learning Experience, Conserving And Restoring Canaveral National Seashore, Thomas Cole

High Impact Practices Student Showcase Fall 2025

Thomas Cole

[email protected]

3177992

My service-learning experience, conserving and restoring Canaveral National Seashore

During my time spent completing service learning course service-learning marine conservation and restoration.. I had the opportunity to participate in a wide range of projects that benefit marine conservation and restoration. These included mangrove gardening, Beach trash removal, constructing oyster habitat structures and a wading bird camera footage experiment. Each of these experiences relate to the conservation and restoration of Canaveral National Seashore. This National park is home to thousands of species of plants and animals, with 47 of those species being federally listed as special concern, …


Shadows From The Double-Wide: A Reflection On Home, Brittani K. Brown Jan 2025

Shadows From The Double-Wide: A Reflection On Home, Brittani K. Brown

Graduate Thesis and Dissertation post-2024

My studio practice acts as a personal anthropological investigation into my upbringing in the rural South. I utilize photographic, textile, print, and virtual mediums that have a unique historical and/or modern connection with the South. Almost a decade after deciding to leave my Southern Baptist religion behind and even longer after covering up my Southern accent, I find myself in a place of tension-ridden nostalgia for the place I grew up.

The community of artists in the Southeast region of the United States continues to grow and create a more cohesive picture of the South and Southern identity through their …


Evolving Perceptions Of Self And Others: The Effects Of Communing With Nature While Thru Hiking The Florida National Scenic Trail, Stella P. Arbeláez Tascón Jan 2025

Evolving Perceptions Of Self And Others: The Effects Of Communing With Nature While Thru Hiking The Florida National Scenic Trail, Stella P. Arbeláez Tascón

Graduate Thesis and Dissertation post-2024

This body of artwork comprises a thesis that documents and exposes the artist’s inner workings as she regained balance after experiencing deep emotional trauma. This individual’s healing transformation was prompted by her immersion in nature while walking the Florida National Scenic Trail in its entirety, 1,130 miles (or 1,818 km), from the Everglades to the panhandle, in three and a half months. The artistic research conducted, and autobiographical body of work created from it, aims to help others reconnect with their own strengths and to seek wellness in the restorative properties of Nature, while advocating for an empathetic approach to …


Environmental Fate Of Trace Anionic Fission Byproducts: An Analysis Of Redox, Sorption, And Incorporation Pathways Of Iodine And Selenium, Ilana B. Szlamkowicz Jan 2025

Environmental Fate Of Trace Anionic Fission Byproducts: An Analysis Of Redox, Sorption, And Incorporation Pathways Of Iodine And Selenium, Ilana B. Szlamkowicz

Graduate Thesis and Dissertation post-2024

The environmental chemistry and mobility of iodine and selenium contaminants were investigated through redox interactions with manganese oxides and incorporation into carbonate minerals. The study examined iodide (I-) and selenite (SeO32-) oxidation under varying pH conditions using manganese oxide minerals, which are geochemical regulators. Using tandem ion chromatography-inductively coupled plasma-mass spectrometry (IC-ICP-MS), the oxidation and speciation of iodine and selenium were quantified under environmentally relevant conditions. The results demonstrate that oxidation of I- and SeO32- by manganese oxides are highly concentration dependent. Acid birnessite, a common manganese oxide, exhibited significant reactivity toward …


A Greener Way To Synthesize Biodiesel: Mechanochemistry With No Added Catalyst, Amanda S. Tanner Jan 2025

A Greener Way To Synthesize Biodiesel: Mechanochemistry With No Added Catalyst, Amanda S. Tanner

Graduate Thesis and Dissertation post-2024

Biodiesel production is currently energy-demanding and produces large volumes of waste despite being marketed as a greener approach to fuel. Here, we report the development and analysis of a more environmentally friendly way of producing biodiesel via mechanochemistry. In as little as one hour, biodiesel can be produced by ball milling intact oilseeds with methanol and no added catalyst. The catalyst for transesterification of oilseeds and methanol via mechanical milling comes from within the seed shells, rather than needing to be added from a separate source. The metals found in the milling media interact with lignin in the seed shells, …


Development Of Degraders To Target Oncogenic Proteins And Efforts Towards The Total Synthesis Of Lycopodium Alkaloids Via Oxidative Dearomatization, Yujia Bian Jan 2025

Development Of Degraders To Target Oncogenic Proteins And Efforts Towards The Total Synthesis Of Lycopodium Alkaloids Via Oxidative Dearomatization, Yujia Bian

Graduate Thesis and Dissertation post-2024

This dissertation focuses on the degradation of SOS1, a guanine nucleotide exchange factor upstream of KRAS, as an alternative therapeutic target for KRAS‑mutant colorectal cancer (CRC). Guided by crystal structures of SOS1 and cereblon, we designed and synthesized a series of PROTACs based on quinazoline‑linker‑lenalidomide hybrids. Among these, the lead degrader induced up to 92% degradation of SOS1 in CRC cell lines and patient‑derived organoids (PDOs), with excellent specificity. In parallel, an AICAR‑derived PROTAC targeting the transmembrane oncoprotein MUC1‑CT in EGFR‑mutant lung cancer achieved time‑dependent and partial target degradation, establishing complementary chemical tools to probe intracellular signaling and …


Evaluating Health And Immune Proxies Within And Across Sea Turtle Life Stages, Tiffany M. Dawson Jan 2025

Evaluating Health And Immune Proxies Within And Across Sea Turtle Life Stages, Tiffany M. Dawson

Graduate Thesis and Dissertation post-2024

Understanding variations in health and immune function across life stages or physiological states is important for population monitoring and for understanding species’ responses to anthropogenic disturbances. Sea turtles are a model species for evaluating these changes within and across life stages due to their long lifespans with ontogenetic habitat and diet shifts. In this dissertation, I tested whether health and immune hematological proxies (Packed Cell Volume [PCV], white blood cell counts, total protein [TP], biochemistry) differed: (1) across the reproductive season, (2) between species and (3) foraging groups, and (4) with reproductive output for adult female turtles (Chapter 2). In …


Carleman Linearization Of Dynamical Systems, And Graph Inverse And Wiener Filtering, Cong Zheng Jan 2025

Carleman Linearization Of Dynamical Systems, And Graph Inverse And Wiener Filtering, Cong Zheng

Graduate Thesis and Dissertation post-2024

Carleman linearization is a mainstream approach for transforming finite-dimensional nonlinear dynamical systems into infinite-dimensional linear systems. It provides accurate approximations of the original nonlinear system over larger regions around the equilibrium for longer time horizons, surpassing the capabilities of conventional first-order linearization. In Chapter 1, we derive explicit error bounds for the finite-section approximation, demonstrating its exponential convergence concerning the finite-section order. We illustrate that for a specific class of nonlinear systems, exponential convergence can be achieved across the entire time horizon, extending to infinity. These results hold significant practical utility, as the proposed error bounds can be used to …


Motion Extrapolation And Motion Dynamics: Are The Motion Dynamics Of Friction Utilized During Motion Extrapolation To Inform Time-To-Contact Estimations?, Genna Telschow Jan 2025

Motion Extrapolation And Motion Dynamics: Are The Motion Dynamics Of Friction Utilized During Motion Extrapolation To Inform Time-To-Contact Estimations?, Genna Telschow

Graduate Thesis and Dissertation post-2024

Cognitive processing delays should cause us to respond too late when making time-to-contact estimations. According to the theory of constructivism, the brain accounts for these delays by supplementing sensory information with higher level cognitive information to create an accurate motion percept. Across the attention, memory, and motion extrapolation literatures there is evidence supporting the use of higher-level information, like motion dynamics, to supplement our visual input. Specifically, previous research suggests we may account for friction’s constraints on motion when interacting with dynamic stimuli. The current research utilizes features that represent friction as both a stopping agent and a motion catalyst …


The Impact Of Virtual Backgrounds In Video-Mediated Selection And The Role Of Candidate Qualifications, Mira Gruber Jan 2025

The Impact Of Virtual Backgrounds In Video-Mediated Selection And The Role Of Candidate Qualifications, Mira Gruber

Graduate Thesis and Dissertation post-2024

Videoconferencing allows users to manage their self-presentation through virtual backgrounds that mask their immediate physical environment. Prior research suggests that backgrounds depicting professional home spaces (e.g., bookshelves) elicit more favorable impressions than those that depict personal home spaces (e.g., bedrooms). Expectancy Violations Theory (EVT) provides a framework for understanding such effects. The present dissertation applied EVT to video-mediated selection interviews, that have become increasingly popular since the COVID-19 pandemic. Given the strict expectations for professionalism in interviews, virtual backgrounds that deviate from such expectations may negatively impact hiring decisions. Consequently, this work examined the impact of two virtual background types, …


Remedios Varo: Peregrinaciones, Julia Condes Jan 2025

Remedios Varo: Peregrinaciones, Julia Condes

Honors Undergraduate Theses

At the time of her death, the artist Remedios Varo (1908–1963) left behind over 500 works of art, the majority of which were created in her adopted country of Mexico. Known for her meticulously crafted fantastical paintings, Varo underwent exile and displacement due to first the Spanish Civil War, and later World War II, which led her to relocate to Mexico, where she would create prolifically for the remainder of her life. This paper will examine the effect of those experiences on the artist and the work she produced, attesting to Varo’s ability to translate complex emotions regarding the human …


The Stigmatization Of Autism – Why It’S Still Present And How It Affects Women And Individuals Assigned Female At Birth (Afab), Emma Drauer Jan 2025

The Stigmatization Of Autism – Why It’S Still Present And How It Affects Women And Individuals Assigned Female At Birth (Afab), Emma Drauer

Honors Undergraduate Theses

The intent of this thesis is to explain some key factors (the theory of mind notion and the narrow perception of autism) that contribute to the stigmatization of autism and the impact this has on autistic women. Autistic women are heavily underrepresented, especially in the scholarly discourse, so this thesis collected first person accounts of autistic experiences through a survey and interviews. This data revealed important information such as the benefits of a diagnosis, how stigma can prevent this and have consequences, and the struggles autistic women face. Unmasking these struggles can help make the general public aware of their …


Genomic Epidemiology Of Staphylococcus Aureus Sequence-Type 97, Eva Armao Jan 2025

Genomic Epidemiology Of Staphylococcus Aureus Sequence-Type 97, Eva Armao

Honors Undergraduate Theses

Staphylococcus aureus (S. aureus) is a gram-positive bacterial pathogen that colonizes human nasal passages, mucous membranes, or the skin of carriers, with colonization commonly found in 20-30% of healthy people. S. aureus has the potential for two types of infection within human hosts: methicillin-susceptible (MSSA) and methicillin-resistant (MRSA). These infections can be further classified based on their route of infection, either known as community-associated (CA), healthcare-associated (HA), or healthcare-associated community-onset (HACO). Upon further investigation of infected populations, specific genetic subtypes of S. aureus, known as sequence types (ST), have been identified globally, with some exhibiting increased virulence among …


The Yeasty Rise Of Conservatism By Fermenting Sourdough, Sydney M. Mcrae Jan 2025

The Yeasty Rise Of Conservatism By Fermenting Sourdough, Sydney M. Mcrae

Honors Undergraduate Theses

Baking has become increasingly popular in the last five years, particularly baking sourdough bread. This is evident through the rise of social media influencers focusing on trad-wife, family, and sourdough content. Trad wife is the term used to describe a a woman who lives a lifestyle that endorses gender roles, child-rearing, and taking care of the family. There is significant crossover between American social conservative ideals and a trad-wife. The emblem for a tradwife has become baking sourdough since the coronavirus pandemic. Previous research has linked the correlation between American social conservatism and the increasingly popular trad-wife phenomenon. Existing literature …


Multi-Criteria Gis Suitability Analysis For Sustainable Agricultural Tourism Site Selection In Peru, Jessica J. Mccord Jan 2025

Multi-Criteria Gis Suitability Analysis For Sustainable Agricultural Tourism Site Selection In Peru, Jessica J. Mccord

Honors Undergraduate Theses

Agricultural tourism offers a mechanism to strengthen rural economies while preserving traditional practices and unique cultural identities. In the Peruvian Andes, rural communities confront increasing challenges in the face of a changing climate and reliance on industrialized agriculture. Rural communities attempt to strike a delicate balance between economic development and heritage preservation. This research utilizes a Geographic Information System (GIS)- based analysis to identify areas best positioned for the development of agritourism initiatives. The suitability analysis integrates both local and global sustainability priorities by incorporating a set of defined criteria that together identify areas that are the most appropriate for …


The Effect Of Social Hierarchy And Captivity On Behavior In Cercopithecus Petaurista, Haley Bombard Jan 2025

The Effect Of Social Hierarchy And Captivity On Behavior In Cercopithecus Petaurista, Haley Bombard

Undergraduate Scholarship and Creative Works

The social hierarchy within three Cercopithecus petaurista individuals was studied to determine how the influence of captivity affects behavior. The three individuals were monitored from August-November, and the data retained was focused on aggression and allogrooming behaviors. The group consisted of one dominant male and two females in the Central Florida Zoo, and behavioral observations were recorded at 10-minute intervals. Results showed that the dominant male infrequently engaged in allogrooming behavior but more often received it from the less dominant females. The hierarchy and social status of the females was shown and influenced by the allogrooming given and received between …


Rhythm Against Poethics, Jayvyn Dacas Jan 2025

Rhythm Against Poethics, Jayvyn Dacas

Honors Undergraduate Theses

This thesis stages an auto-poetic ethnography that listens to, and moves with, the anterior spaces of Black life. Those murmurs, hums, musical hesitations, and infrastructural vibrations that refuse capture by dominant epistemic regimes. Drawing from Ramon Amaro’s reading of Sylvia Wynter, Katherine McKittrick and Alexander Weheliye’s reflections on sound, Fred Moten’s insights on displacement, and Tendayi Sithole’s attention to the phonographic, the project situates music production as method and unworlding. Through engagements with the 808, sampling, sound systems, and embodied listening across Florida. Spaces like the warehouse, the party, record stores, and community become the work of Black voices, and …


A Story Of Oppression A Psychological And Creative Approach, Juan R. Morillo Jan 2025

A Story Of Oppression A Psychological And Creative Approach, Juan R. Morillo

Honors Undergraduate Theses

The aim of this project is to survey the manner in which oppression is expressed in selected works of literature. It is a topic that not only am I familiar with through my studies of literature and psychology, but one that I, as well as every Venezuelan expatriate has witnessed and felt for their country. The project focuses on social and political oppression, using the current Venezuelan crisis as a focal point, and selected literary sources as a framework. I will analyze dystopian classics such as George Orwell's 1984 and Ray Bradbury’s Fahrenheit 451, as well as Margaret Atwood’s The …


Math Escape Room: A Virtual/Blended Problem‑Solving Adventure, Youssef Ibrahim Jan 2025

Math Escape Room: A Virtual/Blended Problem‑Solving Adventure, Youssef Ibrahim

Teaching Online Pedagogical Repository

A narrative‑driven digital escape room turns secondary‑level mathematics review into a collaborative quest: students unlock successive “rooms” by solving algebraic, geometric, and data‑analysis challenges in Google Forms and Genially. Timers, conditional branching, and embedded hints sustain flow, while instructor analytics reveal misconceptions in real time.


Taiwanese Elementary School Teachers’ Mindset Of Content And Language Integrated Learning (Clil) Instruction, Chin-Wen Chien Dec 2024

Taiwanese Elementary School Teachers’ Mindset Of Content And Language Integrated Learning (Clil) Instruction, Chin-Wen Chien

Journal of English Learner Education

Teachers need to undergo a mindset shift in language learning and teaching. This study used both qualitative and quantitative data to explore seven Taiwanese Content and language integrated learning (CLIL) teachers’ mindsets and led to the following major findings. First, the CLIL teachers had a stronger mindset regarding their instructional strategies, lesson preparations, and efficacy, compared to their more moderate mindset regarding their CLIL training and preparation. Secondly, the CLIL teachers had a different mindset regarding language use in their CLIL instruction due to their learners’ English proficiency levels. Finally, their lesson designs were lacking a 4Cs culture. Based on …


Digital Stories Of Resilience: A Case Study Of Urban Community College English Learners, Patricia George Hunter Dec 2024

Digital Stories Of Resilience: A Case Study Of Urban Community College English Learners, Patricia George Hunter

Journal of English Learner Education

This study utilizes a qualitative case study approach to learn how project-based, digital storytelling (DST) voices the resilience of post-secondary English language learners (ELLs) attending a minority-serving, open-access, community college in New York City. Along with many studies that have examined the usefulness of DST in oral production, this research investigates whether project-based digital storytelling enhances students’ understanding of academic content related to resilience and conventional composition. Narrative inquiry (NI) research technique is the basis of the digital story project in an English as a Second Language (ESL) course. In this case, the study relies on observations and artifacts to …


Now I See: Video Supports For English Language Learners, Joanna C. Zimmerle, Hanrui He, Tara Hill Dec 2024

Now I See: Video Supports For English Language Learners, Joanna C. Zimmerle, Hanrui He, Tara Hill

Journal of English Learner Education

General education teachers are often unprepared by teacher preparation programs and limited professional development opportunities to support English Language Learners (ELLs), despite the increasing number of ELLs entering US schools and the trend towards placing them in mainstream classrooms. Video resources offer one viable approach to supporting the language learning of ELLs, drawing upon theoretical frameworks such as dual-coding, constructivist theory, and sociocultural perspectives. This paper describes the use of video resources to assist general education teachers in effectively leveraging videos to support the language learning of ELLs in mainstream classrooms.


Ucf Pegasus Plan - 3rd Grade - Maps And Regions Of The United States Of America, Madison D. Santos, Maggie Beck, Kylie Vandergriff, Courtney Pennock, Jennifer Campos Dec 2024

Ucf Pegasus Plan - 3rd Grade - Maps And Regions Of The United States Of America, Madison D. Santos, Maggie Beck, Kylie Vandergriff, Courtney Pennock, Jennifer Campos

Pegasus Plans: Social Studies Unit Plans for Florida Teachers

During this unit, students will explore maps and their key elements through songs and fun activities. Students will also be exploring the United States of America and its 5 regions by exploring each region and its unique features with songs, books, and interactive activities.