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Climate Change And The Evolution Of Insect Immune Function, Danae Perry Jan 2017

Climate Change And The Evolution Of Insect Immune Function, Danae Perry

Electronic Theses and Dissertations

Insects are ectothermic organisms that have physiological, behavioral and life-history traits directly influenced by their environment. Investigations have shown that many insects use melanin to permanently darken their cuticles in cooler or drier climates to improve thermoregulation and desiccation resistance. Melanin is a major component of pathogen defense in insects. This suggests that environmentally driven adaptive changes in cuticular melanin may non-adaptively shape insect immune function. This hypothesis has been referred to as climate-related Cuticle Dependent Immune Investment (climate-related CDII). Climate-related CDII also suggests that a warming climate could lead to the evolution of a weakened melanin-based immune response due …

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Discovery And Characterization Of Novel Antimicrobials Against Mycobacterium Tuberculosis, Carolina Rodrigues Felix Jan 2017

Discovery And Characterization Of Novel Antimicrobials Against Mycobacterium Tuberculosis, Carolina Rodrigues Felix

Electronic Theses and Dissertations

Tuberculosis disease is currently a global health emergency, causing the most deaths worldwide due a single infectious agent. Eradication of TB is hampered by lack of an effective vaccine and poor treatment options. During infection, host-derived cues such as hypoxia and starvation induce Mycobacterium tuberculosis to halt replication and become dormant, which leads to tolerance to front-line antibiotics used in the TB treatment. This dormant phenotype causes delayed clearance of M. tuberculosis, therefore a long treatment time is required for stable cure without relapse. Poor patient compliance increases the emergence of drug resistant strains, posing yet another challenge for the …

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Getting The Upper Hand: Natural Gesture Interfaces Improve Instructional Efficiency On A Conceptual Computer Lesson, Shannon Bailey Jan 2017

Getting The Upper Hand: Natural Gesture Interfaces Improve Instructional Efficiency On A Conceptual Computer Lesson, Shannon Bailey

Electronic Theses and Dissertations

As gesture-based interactions with computer interfaces become more technologically feasible for educational and training systems, it is important to consider what interactions are best for the learner. Computer interactions should not interfere with learning nor increase the mental effort of completing the lesson. The purpose of the current set of studies was to determine whether natural gesture-based interactions, or instruction of those gestures, help the learner in a computer lesson by increasing learning and reducing mental effort. First, two studies were conducted to determine what gestures were considered natural by participants. Then, those gestures were implemented in an experiment to …

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The Behavior Of Humans And Wildlife With Respect To Roads: Insights For Mitigation And Management, Molly Grace Jan 2017

The Behavior Of Humans And Wildlife With Respect To Roads: Insights For Mitigation And Management, Molly Grace

Electronic Theses and Dissertations

Road ecology is the study of how roads and wildlife interact. Traditionally, road ecologists have primarily focused on one effect of roads: roadkill. Though roadkill can have devastating effects on wildlife populations, roads have sub-lethal impacts that are gaining more and more attention from the scientific community. These sub-lethal impacts include noise, light, and chemical pollution as well as altered habitat structure, which can all influence animal behavior. In this dissertation, I applied a behavioral ecology framework to study specific lethal and sub-lethal road effects with the goal of improving mitigation efforts. In Chapters 1 and 2, I evaluated how …

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83 Orange Peels, Klara Hammoud Jan 2017

83 Orange Peels, Klara Hammoud

Electronic Theses and Dissertations

83 ORANGE PEELS is a feature-length film written and directed by Klara Hammoud and produced by Biddayat as part of the requirements for earning a Master of Fine Arts in Entrepreneurial Digital Cinema from the University of Central Florida. The project aims to challenge existing conventions of the documentary filmmaking on multiple levels – aesthetic, narrative, and technical– while also examining growing importance of workflow throughout all aspects of production. These challenges were both facilitated and necessitated by the limited resources available to the production team and the academic context of the production. This thesis is a record of the …

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Gamification Of Visual Search In Real World Scenes, Alyssa Hess Jan 2017

Gamification Of Visual Search In Real World Scenes, Alyssa Hess

Electronic Theses and Dissertations

Gamification, or the application of game-like features in non-game contexts, has been growing in popularity over the last five years. Specifically, the successful gamification of applications (such as Waze, Foursquare, and Fitocracy) has begun a spike in gamification of more complex tasks, such as learning to use AutoCAD or Photoshop. However, much is unknown about the psychological mapping of gamification or how it translates to behavioral outcomes. This dissertation aims to compare three distinct styles of gamification (avatars, points and feedback, and leaderboards) onto the three basic psychological needs (autonomy, competence, and relatedness). It will assess behavioral outcomes on a …

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Moving Water, Alexandra Arend Jan 2017

Moving Water, Alexandra Arend

Electronic Theses and Dissertations

Moving Water is a novella in which the characters must reckon with grief, time, the divine, and the mysterious bonds forged and broken with each other. Phoebe and her family come to terms with the death of Jason, Phoebe's older brother, and with themselves. Around them, the universe moves in ambivalent splendor, dying and being born anew.

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Using Biomarkers To Assess The Migratory Ecology And Reproduction Of The Florida Green Turtle (Chelonia Mydas), Ryan Chabot Jan 2017

Using Biomarkers To Assess The Migratory Ecology And Reproduction Of The Florida Green Turtle (Chelonia Mydas), Ryan Chabot

Electronic Theses and Dissertations

Migratory connectivity between breeding and foraging areas is a vital component of the ecology of a diverse collection of marine vertebrates. Habitat quality, composition, and resource availability at these locations have direct ramifications for individual fitness. The green turtle (Chelonia mydas) is a long-lived, highly migratory species of conservation concern. Important green turtle nesting habitat in Florida is protected, but more information is needed to identify foraging habitats and the influence these habitats have on reproduction. Here, I used stable isotope analysis of δ13C, δ15N, and δ34S and satellite telemetry validation to determine the number of putative foraging areas used …

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Cross-Continental Insights Into Jaguar (Panthera Onca) Ecology And Conservation, Joe Figel Jan 2017

Cross-Continental Insights Into Jaguar (Panthera Onca) Ecology And Conservation, Joe Figel

Electronic Theses and Dissertations

The jaguar (Panthera onca) is a widely distributed large carnivore and the focal species of a range-wide connectivity initiative known as the jaguar conservation network (JCN). Comprised of ~83 Jaguar Conservation Units (JCUs) and ~75 corridors from northern Mexico to Argentina, the JCN functions as a conduit for jaguar movement and gene flow. Key linkages in the network are imperiled by human population growth, large-scale agriculture, highway expansion, and other infrastructural development. Labeled "corridors of concern," these vulnerable linkages are imperative to the maintenance of connectivity and genetic diversity throughout jaguar distribution. I take a multi-faceted approach to analyze conservation …

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Digital Dissonance: Horror Cultures In The Age Of Convergent Technologies, Daniel Powell Jan 2017

Digital Dissonance: Horror Cultures In The Age Of Convergent Technologies, Daniel Powell

Electronic Theses and Dissertations

The first two decades of the new millennium have witnessed an abundance of change in the areas of textual production, digital communication, and our collective engagement with the Internet. This study explores these changes, which have yielded both positive and negative cultural and developmental outcomes, as products of digital dissonance. Dissonance is characterized by the disruptive consequences inherent in technology's incursion into the print publication cultures of the twentieth century, the explosion in social-media interaction that is changing the complexion of human contact, and our expanding reliance on the World Wide Web for negotiating commerce, culture, and communication. This study …

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Cathepsin B Regulates Vldl Secretion Through Lfabp Cleavage, Simeon Thibeaux Jan 2017

Cathepsin B Regulates Vldl Secretion Through Lfabp Cleavage, Simeon Thibeaux

Electronic Theses and Dissertations

The liver is tasked with managing the concentration of various metabolites in the blood, and of particular importance is the uptake of free fatty-acid (FFA), as elevated concentrations of FFA are toxic to cells. FFAs are transported across the cell membrane by CD36 and distributed by LFABP to the endoplasmic reticulum (ER), where they are esterified to glycerol, yielding more chemically inert triglyceride (TAG), which is essential to the process of VLDL assembly. VLDL secretion distributes energy rich TAG to peripheral tissues, and its dysfunction leads to hepatic steatosis, which may progress into hepatocellular carcinoma. The present study examined the …

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Investigating Instructional Designers' Decisions Regarding The Use Of Multimedia Learning Principles In E-Learning Course Design, Victor Arguelles Jan 2017

Investigating Instructional Designers' Decisions Regarding The Use Of Multimedia Learning Principles In E-Learning Course Design, Victor Arguelles

Electronic Theses and Dissertations

This study employed a qualitative research design using the Decomposed Theory of Planned Behavior (DTPB) to investigate instructional designers' use of multimedia learning principles (MLPs) in e-learning course design. While MLPs have been extensively studied in educational research and are largely associated with positive results, evidence suggests that instructional designers are not uniformly implementing these strategies when designing e-learning environments. The purpose of this study was twofold: (a) to understand better the alignment between instructional designers' knowledge and demonstrated implementation of MLPs; and (b) to understand the factors that influence instructional designers' intent and actual implementation of MLPs in their …

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A Study Of Central Florida College Students' Acceptance Of The Theory Of Evolution, Microevolution, Macroevolution, And Human Evolution, David Schleith Jan 2017

A Study Of Central Florida College Students' Acceptance Of The Theory Of Evolution, Microevolution, Macroevolution, And Human Evolution, David Schleith

Electronic Theses and Dissertations

In order to study the teaching and learning of the theory of evolution and determine levels of acceptance of the theory of evolution among college students studying biology in Central Florida, the Inventory of Student Evolution Acceptance, I-SEA, was administered to over 500 university students enrolled in a biology course during the Fall 2016 term. An analysis of 489 completed surveys demonstrated strong overall acceptance of the theory of evolution (average score = 103 out of 120 total possible). Of all students, 78% fell into the category of very high acceptance of the theory of evolution. Students who reported attending …

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A Snapchat Marketing Perspective: Examining The Personality Traits And Motives That Predict Attitudes Toward And Engagement With Non-Sponsored And Sponsored Content In Snapchat., Tiany Sousa Garnica Jan 2017

A Snapchat Marketing Perspective: Examining The Personality Traits And Motives That Predict Attitudes Toward And Engagement With Non-Sponsored And Sponsored Content In Snapchat., Tiany Sousa Garnica

Electronic Theses and Dissertations

Social networking sites (SNS) have revolutionized the communication between consumers and brands, publishers, and marketers. These platforms have become a way for advertisers to communicate directly and engage users with content that is innovative and less intrusive. The aim of this research is to examine the personality traits and motives (based on the uses and gratifications theory) that predict attitudes toward and engagement with non-sponsored and sponsored content in Snapchat. An online survey with 606 participants showed that the main motives of using Snapchat were social information seeking, entertainment, and impression management. Multiple regression analyses were used to determine what …

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Quantification Of Non-Stoichiometry And Impurities In Transparent Yag Ceramics By Laser-Induced Breakdown Spectroscopy (Libs), Sudeep Pandey Jan 2017

Quantification Of Non-Stoichiometry And Impurities In Transparent Yag Ceramics By Laser-Induced Breakdown Spectroscopy (Libs), Sudeep Pandey

Electronic Theses and Dissertations

Transparent ceramics are an important class of optical materials with applications in street-lighting, high-strength windows, electro- and magneto-optical isolators, high-power laser gain media and nuclear radiation detectors. Compared to single-crystal growth, ceramic processing enables size scalability, near net-shape forming and prevents issues associated with dopant segregation and inhomogeneity, such as stress-induced birefringence and wavefront distortions. The fabrication of high optical grade ceramics by route of powder sintering, relies on a controlled set of techniques preventing the formation of scattering centers (pores and secondary phases) and harmful point defects (color centers, charge-carrier trapping sites). This thesis work investigates a novel approach …

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Implication Of Alpha-Synuclein Transcriptional Regulation And Mutagenesis In The Pathogenesis Of Sporadic Parkinson's Disease, Sambuddha Basu Jan 2017

Implication Of Alpha-Synuclein Transcriptional Regulation And Mutagenesis In The Pathogenesis Of Sporadic Parkinson's Disease, Sambuddha Basu

Electronic Theses and Dissertations

Parkinson's disease (PD) is an age-related neurodegenerative disorder characterized by selective loss of dopaminergic neurons (DA neurons) from the substantia nigra (SN) of the mid-brain. PD is classically associated with cytoplasmic inclusion of aggregated proteins called Lewy bodies. alpha-synuclein (α-SYN) coded by the gene SNCA, is one of the major components of Lewy body and neurite along with several other proteins like ubiquitin, neurofilament to name a few. PD is broadly categorized into two groups based on their incidence of occurrence. First is the familial form that occurs due to known genetic aberrations like mutation, gene duplication/triplication in important PD …

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Discovery And Characterization Of Antimalarials With Novel Mechanisms Of Action, Bracken Roberts Jan 2017

Discovery And Characterization Of Antimalarials With Novel Mechanisms Of Action, Bracken Roberts

Electronic Theses and Dissertations

Malaria kills over 500,000 people each year and over a third of the global population is at risk of infection. Though the human race has been fighting the malaria war for over 4,000 years and we have made great strides in eliminating malaria from many countries, we are treading on the edge of what could be another malaria epidemic primarily due to widespread drug resistance. There are documented cases of resistance for every known antimalarial in use today, including Artemisinins. It is critical that we open a new window of discovery in development of next generation antimalarials that circumvent current …

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An Exploratory Mixed Methods Study Of Student Awareness In Expressing Emotions And Identifying The Emotions Of Others: Through The Mirror Looking Glass, Christine K. Duff Jan 2017

An Exploratory Mixed Methods Study Of Student Awareness In Expressing Emotions And Identifying The Emotions Of Others: Through The Mirror Looking Glass, Christine K. Duff

Electronic Theses and Dissertations

The goal of this research was to determine how the self-awareness process of expressing emotions and identifying emotions of others was impacted during a mirror-based intervention for first grade students from inclusive classrooms. The study investigated the extent that a two-way mirror display helped eight students increase their level of awareness when expressing emotions and identifying the emotions of others. Traditional assessment measures for assessing empathy and accuracy in perception of emotions of others have relied on binary, forced choice responses that have not addressed a student's level of awareness, or increased awareness in identifying the emotions of others. Further, …

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Examining The Role Of Cardiovascular And Cognitive Fitness In Goal-Directed Aiming Across The Lifespan, Michael Rupp Jan 2017

Examining The Role Of Cardiovascular And Cognitive Fitness In Goal-Directed Aiming Across The Lifespan, Michael Rupp

Electronic Theses and Dissertations

Older adults experience more difficulties completing goal directed movements than younger adults. The reasons for this have not been completely elucidated within the research literature; however, it is thought that age related movement differences are due to at least one of three possible reasons. The current study investigated the influence of these three hypotheses: (1) biomechanical changes (limbs, joints, or muscles), (2) sensory feedback processing ability, or (3) differences in overall movement strategy on movement kinematics. Additionally, physical activi-ty is known to improve both physical and cognitive functioning and staying cognitively active may also attenuate age-related declines in cognitive ability; …

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Modern Arcana, Kaitlin Kolhoff Jan 2017

Modern Arcana, Kaitlin Kolhoff

Electronic Theses and Dissertations

Modern Arcana is a collection of eleven short stories, totaling 124 pages, and was written in pursuit of a Master of Fine Arts in Creative Writing. This collection was written through multiple stages of planning and revising work in response to the feedback of peers and instructors. Through writing this thesis, I explored my own relationship to the craft of creative writing and composition, as well as the familiarized myself with the current work being published in my field and genre. This collection is made unique through the sharing magical elements between pieces and the themes of agency in relation …

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School Has A Bad Storyline: Gamification In Educational Environments, Irene L. Pynn Jan 2017

School Has A Bad Storyline: Gamification In Educational Environments, Irene L. Pynn

Electronic Theses and Dissertations

School often has low engagement and frustrating or absent options for the kind of agency the Federal Government's 2016 National Education Technology Plan now recommends educators include in their curriculum. Video games offer opportunities for people to participate in critical problem solving through creative projects. From balancing character statistics, to collaborating with other players, to making ethical and tactical decisions that can change the outcome of the story, successful games draw on the player's interest in learning and analyzing numbers, locations, visual clues, narrative elements, people, and more. One useful example may be found in visual novels (VNs), a medium …

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Effects Of Symbol Type On Naming And Identification Of Graphic Symbols By Typically Developing Three, Four, Five And Six-Year Olds Children., Pamela Resnick Jan 2017

Effects Of Symbol Type On Naming And Identification Of Graphic Symbols By Typically Developing Three, Four, Five And Six-Year Olds Children., Pamela Resnick

Electronic Theses and Dissertations

Speech-language pathologists and educators face unique challenges in assessing the language skills of children with complex communication needs due to the wide array of impairments with which these individuals present. For example, most receptive language assessment tools require that children either point to or label line drawings to determine whether or not they comprehend the depicted concepts; task demands such as these preclude administering such assessment tools with children who are unable to physically point to or verbally label presented stimuli. In light of these challenges, the use of eye tracking technologies has become particularly appealing since this alternate response …

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Using Molecular Genetic And Demographic Tools To Improve Management Of Ex Situ Avian Populations, Gina Ferrie Jan 2017

Using Molecular Genetic And Demographic Tools To Improve Management Of Ex Situ Avian Populations, Gina Ferrie

Electronic Theses and Dissertations

Small populations, specifically those that are isolated from others, are more prone to extinction than larger inter-connected populations. The risks that these small isolated populations face include loss of genetic diversity due to founder effects and inbreeding due to population bottlenecks, as well as demographic uncertainty due to fluctuating fecundity and mortality rates and impacts of external environmental factors. Ex situ populations, including those managed as conservation breeding programs with species recovery aims, as well as those that do not have reintroduction goals but are managed for long term population sustainability, suffer from the same extinction risks as small and …

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Development Of Molecular Diagnostic Tools For Mycobacterium Species, Hillary Bengtson Jan 2017

Development Of Molecular Diagnostic Tools For Mycobacterium Species, Hillary Bengtson

Electronic Theses and Dissertations

This dissertation focuses on the development of diagnostic tools for mycobacteria using hybridization based technologies including binary deoxyribozyme (BiDz) sensors and microarrays. The genus Mycobacterium, is a diverse group of bacteria containing 150+ species including M. tuberculosis (M.tb) and non-tuberculous mycobacteria (NTM) which exhibit a range of pathogenicity, drug susceptibility and growth characteristics. M. tuberculosis (M.tb) is the causative agent of tuberculosis (TB) and the leading cause of infectious disease related deaths worldwide. The control of TB is limited by the lack of sensitive and specific diagnostic tools available at the point of care (POC). The studies presented here illustrate …

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Natural Disasters, Rebecca Cobb Jan 2017

Natural Disasters, Rebecca Cobb

Electronic Theses and Dissertations

Natural Disasters is a collection of twelve short stories that feature a variety of narrators as they interact with the ones they love. In these stories, characters experience puberty, friendship, love, loss, trauma, and the everyday magic of living as they fight to master their own failings. Those lucky enough find solace in the forgiving beauty of nature, while others succumb to the untamable power of its disasters. This thesis is useful, important, and unique as it focuses on the stories of a variety of characters, mostly women and children, and displays the beauty and fearsome power of nature as …

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Targeted Therapy Development For Neurofibromatosis Type 2, Marisa Fuse Jan 2017

Targeted Therapy Development For Neurofibromatosis Type 2, Marisa Fuse

Electronic Theses and Dissertations

Neurofibromatosis type 2 (NF2) is a debilitating disease characterized by the formation of bilateral vestibular schwannomas, which compress the vestibulocochlear nerve and cause deafness. Additional peripheral schwannomas, meningiomas and ependymomas may also form. NF2 is caused by mutations in the NF2 gene, resulting in the loss of function of the merlin tumor suppressor. Merlin functions in multiple signaling pathways and its absence in Schwann cells yields increased cell survival and proliferation, thereby causing schwannoma formation. First line treatment for NF2 is watchful waiting and surgical removal of tumors, potentially resulting in facial paralysis and deafness. To date, there are no …

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Reproductive Life History And Signal Evolution In A Multi-Species Assemblage Of Electric Fish, Joseph Waddell Jan 2017

Reproductive Life History And Signal Evolution In A Multi-Species Assemblage Of Electric Fish, Joseph Waddell

Electronic Theses and Dissertations

Animals that co-occur in sympatry with multiple closely-related species use reproductive mate attraction signals not only to assess the quality of a potential conspecific mate (sexual selection), but also to discriminate conspecifics from heterospecifics (species recognition). However, the extent to which sexual selection and species recognition may interact, or even conflict, is poorly known. Neotropical electric fish offer unrivaled opportunities for understanding this problem. They generate simple, stereotyped mate attraction signals that are easy to record and quantify, and that are well-understood from the neurobiological perspective. Additionally, they live in electrically-crowded environments, where multiple congeners live and reproduce in close …

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Women In White: My Journey Into Color, Madison Tarbox Jan 2017

Women In White: My Journey Into Color, Madison Tarbox

Electronic Theses and Dissertations

In many religious circles white is a symbol for purity, cleanliness, and perfection. However, white is also synonymous with empty, blank, and colorless. Women in White: My journey into color is a project centralized around a personal study of the cultural pressures of "perfection" presented both in religious cultures and in the every-day life of a performer. Utilizing the catalyst of a cabaret-style performance, Women in White explores the struggles of nine different female characters in the musical theatre cannon and aims to draw a personal connection from their journey. Inspired by the wise words of my own mother, this …

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Exploring Interactions Between Adult English Learners And Their Teachlive Digital Character Peers, Ting Yan Jan 2017

Exploring Interactions Between Adult English Learners And Their Teachlive Digital Character Peers, Ting Yan

Electronic Theses and Dissertations

Peer interaction is an important part of language learning. The results of previous studies showed advantages and disadvantages of peer interaction between native speakers and English learners. Using the educational simulation platform TeachLivE as the interaction platform, this qualitative descriptive case study explored the possibilities of bridging the gap between classroom language practice and real-life second language communication. The study recruited eight participants for a task-based interaction project. Using conversation analysis, the study revealed details in communication between adult English learners and their digital character peers. During the interactions, the participants were actively involved and the most frequent communication patterns …

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A Chemical And Genetic Approach To Study The Polyamine Transport System In Drosophila, Minpei Wang Jan 2017

A Chemical And Genetic Approach To Study The Polyamine Transport System In Drosophila, Minpei Wang

Electronic Theses and Dissertations

Polyamines are small cationic molecules that play important roles in most vital cellular processes including cell growth and proliferation, regulation of chromatin structure, translation and programmed cell death. Cellular polyamine pools are maintained by a balance between biosynthesis and transport (export and import). Increased polyamine biosynthesis activity and an active transport system are characteristics of many cancer cell lines, and polyamine depletion has been shown to be a viable anticancer strategy. Polyamine levels can be depleted by α-difluoromethylornithine (DFMO), an inhibitor of the key polyamine biosynthesis enzyme ornithine decarboxylase. However, malignant cells often circumvent DFMO therapy by up-regulating polyamine import; …

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