Digital Commons Network^™

Development And Characterization Of An Autologous Whole Cell Breast Cancer Vaccine, Samantha Leigh Kurtz

Graduate Theses and Dissertations

Approximately 40,000 women will die from breast cancer in the United States in 2014. About 90% of these deaths will be due to metastases, rather than the primary tumor and majority of metastases are due to the recurrence and progression of non-metastatic disease. Current adjuvant treatments, such as chemotherapy and radiation, have severe side effects and may result in overtreatment and drug resistance.

Since greater than 90% of patients are diagnosed between stages I-III and have minimal residual disease after treatment, there is an opportunity to treat patients with an autologous breast cancer vaccine. Autologous vaccines under development have a …

Population Genetics, Distributions And Phenology Of Bombus Latreille, 1802 And Xylocopa Latreille, 1802 (Hymenoptera: Apidae), Amber Dawn Tripodi

Graduate Theses and Dissertations

This work addresses multiple knowledge gaps in bee ecology, population health and phylogeography in order to provide insights into the changing distributions of native bees. A comparison of Arkansas bumble bee records mirrors range-wide surveys, with records of stable species (Bombus bimaculatus Cresson, 1863 and B. impatiens Cresson, 1863) increasing three-fold, and records of the declining B. pensylvanicus (DeGeer, 1773) dropping to 60% of historical levels. However, nationally-recommended conservation-genetics tools did not mirror these results on a regional level. Stable and declining species had equivalent genetic diversity in samples from Arkansas and Tennessee (H_S range: 0.46-0.63). Diploid males, …

Monsters In Common: Identity And Community In Postapocalyptic Science Fiction After 9/11, Jeremy J. Burns

Graduate Theses and Dissertations

In the aftermath 11 September, 2001, postapocalyptic science fiction has offered a way to make sense of the events of that day, as well as the years of social, cultural and political upheaval that have followed. In many ways, 9/11 began immediately to take on apocalyptic significance in the American national narrative, seemingly marking the end of one period and the beginning of another, entirely different one. To think of 9/11 as a kind of apocalyptic break with the past, however, does not tell the whole story. Moreover, such thinking denies key historical linkages between the American response to 9/11 …

Screening Diverse Soybean Germplasm For Water-Logging Tolerance, John Franklin Carlin

Graduate Theses and Dissertations

Water-logging can be detrimental to soybean growth and development; effects range from chlorosis and stunting to yield loss and plant death. Soybean response to, and the effects of, water-logging are dependent on the growth-stage of the plant at the initiation of water-logging. The objectives of this study were to screen a diverse soybean germplasm collection for water-logging tolerance (WLT) at both the V5 and R1 growth stage and to develop a method to screen soybean for WLT in greenhouse. One hundred thirty five genotypes consisting of historical genotypes, PIs, drought and WLT tolerant breeding lines were screened for WLT in …

Outstanding Educational Performance Awards: Highlighting High-Achieving Arkansas Schools, 2014, Charlene A. Reid, Gary W. Ritter

Arkansas Education Reports

The GPA measure, we believe, is a better representation of student achievement on statewide standardized exams. In this report, we are presenting a list of the top 25 schools in each area. In some cases, these "top 25 lists" will contain more than 25 schools as some schools' GPA scores will be identical. This is not a new phenomenon, as we also exceeded 25 schools in previous reports when using the percent proficient and advanced metric as an indicator for student achievement; however, there are fewer ties using the more precise GPA measure.

After we present our overall snapshot of …

Small Quantum Dots Conjugated To Nanobodies As Immunofluorescence Probes For Nanometric Microscopy, Yong Wang, En Cai, Tobias Rosenkranz, Pinghua Ge, Kai Wen Teng, Sung Jun Lim, Andrew M. Smith, Hee Jung Chung, Frederick Sachs, William N. Green, Philip Gottlieb, Paul R. Selvin

Physics Faculty Publications and Presentations

Immunofluorescence, a powerful technique to detect specific targets using fluorescently labeled antibodies, has been widely used in both scientific research and clinical diagnostics. The probes should be made with small antibodies and high brightness. We conjugated GFP binding protein (GBP) nanobodies, small single-chain antibodies from llamas, with new ∼7 nm quantum dots. These provide simple and versatile immunofluorescence nanoprobes with nanometer accuracy and resolution. Using the new probes we tracked the walking of individual kinesin motors and measured their 8 nm step sizes; we tracked Piezo1 channels, which are eukaryotic mechanosensitive channels; we also tracked AMPA receptors on living neurons. …

Minutes Of The Faculty Senate Meeting, November 12, 2014, University Of Arkansas, Fayetteville. Faculty Senate

Faculty Senate Minutes

No abstract provided.

Mole Street Journal, October 2014, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

Arkansas Animal Science Department Report 2014, David L. Kreider, Paul Beck

Arkansas Agricultural Experiment Station Research Series

No abstract provided.

Outstanding Educational Performance Awards: Highlighting High-Achieving Arkansas Schools, 2014, Charlene A. Reid, Gary W. Ritter

Arkansas Education Reports

The GPA measure, we believe, is a better representation of student achievement on statewide standardized exams. In this report, we are presenting a list of the top 25 schools in each area. In some cases, these "top 25 lists" will contain more than 25 schools as some schools' GPA scores will be identical. This is not a new phenomenon, as we also exceeded 25 schools in previous reports when using the percent proficient and advanced metric as an indicator for student achievement; however, there are fewer ties using the more precise GPA measure.

After we present our overall snapshot of …

Economic Contribution Of Agriculture And Food To Arkansas' Gross Domestic Product 1997-2012, Leah English, Jennie Popp, Wayne Miller

AAES Research Reports and Research Bulletins

Agricultural production, processing, and retail industries are major contributors to the Arkansas economy in terms of GDP. Agriculture contributes to the economy through direct agricultural production, value-added processing, and agricultural retail activities, and it also plays an important role through its interactions with other sectors. The use of non-agricultural goods and services as inputs into the agricultural sector promotes diversified growth in Arkansas’ economy; thus agriculture remains a vital part of Arkansas’ economy. This report: 1) compares the relative size of the Agriculture and Food Sector in Arkansas with those of neighboring states, the Southeastern region of the United States, …

Outstanding Educational Performance Awards: Highlighting High-Achieving Arkansas Schools, 2014, Charlene A. Reid, Gary W. Ritter

Arkansas Education Reports

The GPA measure, we believe, is a better representation of student achievement on statewide standardized exams. In this report, we are presenting a list of the top 25 schools in each area. In some cases, these "top 25 lists" will contain more than 25 schools as some schools' GPA scores will be identical. This is not a new phenomenon, as we also exceeded 25 schools in previous reports when using the percent proficient and advanced metric as an indicator for student achievement; however, there are fewer ties using the more precise GPA measure.

After we present our overall snapshot of …

Jeanne Clery Disclosure Of Campus Security Policy And Campus Crime Statistics Report, 2013, University Of Arkansas, Fayetteville. Police Department

Jeanne Clery Disclosure of Campus Security Policy

No abstract provided.

Next Generation Science Standards, Sarah C. Mckenzie, Gary W. Ritter

Policy Briefs

This policy brief provides an overview of the Next Generation Science Standards (NGSS), voluntary state science standards that are intended to improve the quality of science instruction in the U.S. The brief discusses the history of science standards, the development of the NGSS and its current status, arguments for and against the standards, and the status of the NGSS in Arkansas.

Application Of High-Resolution Spectral Absorbance Measurements To Determine Dissolved Organic Carbon Concentration In Remote Areas, Armine Avagyan, Benjamin R. K. Runkle, Lars Kutzbach

Biological and Agricultural Engineering Faculty Publications and Presentations

Accurate quantification of dissolved organic carbon (DOC) in surface and soil pore waters is crucial for understanding changes in water resources under the influence of climate and land use changes. Sampling and laboratory analysis of DOC content at a sufficient temporal frequency are especially difficult to achieve for natural DOC sources like the extensive boreal and arctic mire landscapes due to their remoteness. Therefore, the goals of this paper are (1) to investigate the performance of a portable, high-resolution ultraviolet–visible light spectroscopic method for determining the DOC content of surface and soil pore water samples from a boreal mire complex …

Outstanding Educational Performance Awards: Highlighting High-Achieving Arkansas Schools, 2014, Charlene A. Reid, Gary W. Ritter

Arkansas Education Reports

The GPA measure, we believe, is a better representation of student achievement on statewide standardized exams. In this report, we are presenting a list of the top 25 schools in each area. In some cases, these "top 25 lists" will contain more than 25 schools as some schools' GPA scores will be identical. This is not a new phenomenon, as we also exceeded 25 schools in previous reports when using the percent proficient and advanced metric as an indicator for student achievement; however, there are fewer ties using the more precise GPA measure.

After we present our overall snapshot of …

Outstanding Educational Performance Awards: Highlighting High-Achieving Arkansas Schools, 2014, Charlene A. Reid, Gary W. Ritter

Arkansas Education Reports

In this report, we are presenting a list of the top 25 schools in each area. In some cases, these "top 25 lists" will contain more than 25 schools as some schools' GPA scores will be identical. This is not a new phenomenon, as we also exceeded 25 schools in previous reports when using the percent proficient and advanced metric as an indicator for student achievement; however, there are fewer ties using the more precise GPA measure.

After we present our overall snapshot of high-performing schools, we will release subsequent reports every few weeks focusing on different subsets of schools. …

Athletic Training Education Program Newsletter, Fall 2014, University Of Arkansas, Fayetteville. Athletic Training Education Program

Athletic Training Education Newsletter

No abstract provided.

Research Frontiers, Fall 2014, University Of Arkansas Fayetteville. Office Of University Relations

Research Frontiers

No abstract provided.

Phytochemical, Antioxidant And Antibacterialpotential Of Elaeagnus Kologa (Schlecht.) Leaf., Zoe Merculieff, Shubharani Ramnath, Seethalakshmi Madhukar Sankoli, Sivaram Venkataramegowda, Ganti S. Murthy, Ruben Michael Ceballos

Biological Sciences Faculty Publications and Presentations

Objective To screen different solvent extracts of Elaeagnus kologa (E. kologa) leaf to determine the phytochemicals, potent antioxidant and antibacterial activity to find out the possible source of applied pharmaceutical formulations. Methods Solvent extracts of leaf material were prepared using the Soxhlet apparatus. A study was performed on antioxidant activity of methanolic extract of leaf by 1-1-diphenyl-2-picrylhydrazyl method. The phenolic and flavonoid content of all the fractions were determined using high performance liquid chromatography. Leaves were also subjected to protein and carbohydrate test. Results The total phenols, flavonoids were found to be high in petroleum ether as compare to other …

2013-14 Arkansas Test Results, Sarah C. Mckenzie, Gary W. Ritter

Policy Briefs

In late July, the Arkansas Department of Education (ADE) released the 2013- 14 test score results. The following brief highlights the results of these tests, compares achievement scores over time, and provides a glimpse of regional achievement results for the following exams:  Benchmark Exam (Grades 3-8)  End-of-Course Exam (Algebra I, Geometry, Biology, and Grade 11 Literacy).  Iowa Test of Basic Skills (Grades 1-9)

Method Of Controlled Drug Release From A Liposome Carrier, Daniel Fologea, Greg J. Salamo, Ralph Henry, Michael J. Borrelli, Peter M. Corry

Patents Granted

Methods and compositions for the controlled release of a drug or agent from a liposome using light or radiation are disclosed. Compositions comprising liposomes having a lipid layer, wherein the liposomes contain an agent, an enzyme capable of releasing the agent from the liposome, and an enzyme activator sequestered by a molecular cage are also disclosed, in addition to methods of delivering an agent to a target in a subject.

Annual Report, 2013-2014, University Of Arkansas, Fayetteville. College Of Engineering

College of Engineering Annual Report

No abstract provided.

Mole Street Journal, July 2014, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

Consumer Perceptions And Knowledge Of Genetically Modified Organisms In Belgium: A Case Study Of The Potato Event, Maggie Jo Pruitt

Agricultural Education, Communications and Technology Undergraduate Honors Theses

It is widely known that Europeans have the strongest resistance to genetically modified organisms (GMO). Despite biotechnology advancements in the United States and other countries, European Union (EU) policymakers continue to argue over market-driven GMO regulations. Because humans depend on agriculture for survival, they tend to be concerned with the fundamental risk of combining agricultural production and scientific/technological advancements. In 2011, scientists at a large research institution in Belgium planted a field trial of GM potatoes (during this time GM foods were not in the market). On May 29, an activist group arrived at the field and uprooted the potatoes. …

Investigation Of The Flow And Fate Of Nitrate In Epikarst At The Savoy Experimental Watershed, Northwest Arkansas, Jozef Laincz

Graduate Theses and Dissertations

Many karst aquifers are at high risk of nitrate contamination due to a combination of vulnerable geology characterized by thin soils and conduit flow, and excess inputs of nutrients from animal feeding operations. One zone that is present in many karst regions and could play an important role in nitrate attenuation due to properties such as increased residence time and matrix-water contact is the upper, weathered portion of karst, the epikarst. However, the understanding of this role is lacking, and the objective of this dissertation was to elucidate it. The fate of nitrate in the epikarst was traced along a …

Large-Scale Solution Approaches For Healthcare And Supply Chain Scheduling, Ridvan Gedik

Graduate Theses and Dissertations

This research proposes novel solution techniques for two real world problems. We first consider a patient scheduling problem in a proton therapy facility with deterministic patient arrivals. In order to assess the impacts of several operational constraints, we propose single and multi-criteria linear programming models. In addition, we ensure that the strategic patient mix restrictions predetermined by the decision makers are also enforced within the planning horizon. We study the mathematical structures of the single criteria model with strict patient mix restrictions and derive analytical equations for the optimal solutions under several operational restrictions. These efforts lead to a set …

Summaries Of Arkansas Cotton Research 2013, Derrick M. Oosterhuis

Arkansas Agricultural Experiment Station Research Series

No abstract provided.

3-D Morphometric Analysis Of The Primate Elbow Joint, Seth Brockman Boren

Graduate Theses and Dissertations

Large body size requires limb joints capable of supporting said weight, and a species exhibiting sexual size dimorphism may necessitate joint size differences between the sexes of the species. If habitual behavior differs with body size, one may expect to see significant variation in joint morphology between species and the sexes within species. The following analysis tests two hypotheses: (1) that significant differences in joint size between males and females correlate with the magnitude of sexual dimorphism and (2) that there is significant interspecific variance in joint shape between males and females of the same species. The first hypothesis is …

Assessment Of Nitrifying Bacteria In Massard Plant Using Molecular Tools, Jennifer Puanani Holmes-Smith

Civil Engineering Undergraduate Honors Theses

The discharge of nutrients (such as nitrogen and phosphorus) from wastewater treatment plants (WWTP) has become an increasingly important issue in the United States. Ammonia (NH3) is a common contaminant found in domestic wastewater and agricultural runoff. It can cause toxicity in fish if left untreated. The United States Environmental Protection Agency (EPA) recommends low national criteria for ammonia limits in freshwater. With these greater restrictions, ammonia-nitrogen limit compliance (5 mg/L) has become an issue at the Massard WWTP in Fort Smith, Arkansas. The purpose of this research is to assess the ammonia removal in the Massard WWTP in order …