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Parenting The Gifted: Caregivers’ Perspectives Of Challenges And Their Confidence To Support Their Exceptional Children, Kristi A. Mascher Dec 2021

Parenting The Gifted: Caregivers’ Perspectives Of Challenges And Their Confidence To Support Their Exceptional Children, Kristi A. Mascher

Graduate Theses and Dissertations

This phenomenological study uses Bandura’s theory of self-efficacy (1977) to examine the lived experiences of eight parents of gifted children and how their experiences, both positive and negative, shape their perception of their confidence and may contribute to building future supports for gifted parents and caregivers. Qualitative data, collected through semi-structured interviews and analyzed with an interpretive/hermeneutic lens, provides seven major themes derived from the voices of parents with children of varying ages and exceptionalities. In addition, this study concludes with a discussion surrounding the additional challenges associated with parenting the exceptional, frameworks for gifted parent support systems, as well …


Remixed, Remastered: Investigating Organizational Adaptation In Higher Music Education, Jacob Bruce Hertzog Dec 2021

Remixed, Remastered: Investigating Organizational Adaptation In Higher Music Education, Jacob Bruce Hertzog

Graduate Theses and Dissertations

Higher music education presents a unique opportunity to examine change within higher education due to the digital revolution in the music industry over the past two decades. The purpose for conducting this study was to describe, map, and explain the strategies that higher music education programs are using to adapt to the digital revolution in the music industry. This study was grounded in organizational adaptation theory, drawing upon nine well-established theories: population ecology, life cycles, strategic choice, isomorphism, symbolic action, resource dependence, cybernetics, and network theory. Critical concepts of the turbulent environment, environmental perception, and organizational adaptation strategy emerged from …


Queering The Metanarrative Of Domesticity: Chosen Families In Late Nineteenth- Century American Women's Literature, Sharla Rosenbaum Dec 2021

Queering The Metanarrative Of Domesticity: Chosen Families In Late Nineteenth- Century American Women's Literature, Sharla Rosenbaum

Graduate Theses and Dissertations

My primary purpose in this project is to dispel the notion that the white, bourgeois, patriarchal, nuclear family believed by millions of US citizens to have once monopolized the United States’s cultural landscape through an examination of how women authors in the United States constructed families in literature immediately following the Civil War. Not only do the novels under examination reflect diverse representations of families, but they also reflect those images from diverse perspectives. I will use a Marxist lens to explore class and ideologic interpellation; a renegade global feminist lens to explore failure and differential consciousness; a queer and …


Mitigating Rice Injury Caused By Florpyrauxifen-Benzyl And Optimizing Florpyrauxifen-Benzyl Rate And Timing For Use In Furrow-Irrigated Rice, James Winston Beesinger Dec 2021

Mitigating Rice Injury Caused By Florpyrauxifen-Benzyl And Optimizing Florpyrauxifen-Benzyl Rate And Timing For Use In Furrow-Irrigated Rice, James Winston Beesinger

Graduate Theses and Dissertations

Florpyrauxifen-benzyl (synthetic auxin, WSSA Group 4) is a postemergence, broad-spectrum herbicide labeled for use in Mid-South rice (Oryza sativa L.) production. Introduction of florpyrauxifen-benzyl to Arkansas rice production led to observations of varying levels of injury caused by the herbicide across cultivars and environments. Findings from previous research indicated hybrid long-grain rice and medium-grain rice were more susceptible to florpyrauxifen-benzyl and hypotheses were formed using this research regarding the impact of environmental conditions on the amount of injury observed. Concerns of yield loss, delay in maturity and loss of groundcover as well as questions regarding the ability of florpyrauxifen-benzyl to …


Effects Of Extrinsic And Intrinsic Factors On Meat Quality And Muscle Biology Of Livestock, Yongjie Wang Dec 2021

Effects Of Extrinsic And Intrinsic Factors On Meat Quality And Muscle Biology Of Livestock, Yongjie Wang

Graduate Theses and Dissertations

In order to improve the meat quality of livestock, intrinsic and extrinsic factors that impact meat quality have been studied for a long time to optimize production quality. Nutrition, breed, and environment are the three most common factors to improve meat quality and muscle growth. The objective of this thesis is to perform a horizontal comparison of the effects of crude protein levels, breeds, and topsoil on the growth performance, muscle development, and meat quality of livestock, and also a longitudinal analysis using RNA-seq, RT-qPCR, and Western-blot to investigate the changes in genes and proteins related to muscle growth, and …


Forced And Unforced Permafrost Changes In The Northern Hemisphere During 1901-2100, Hong Guo Dec 2021

Forced And Unforced Permafrost Changes In The Northern Hemisphere During 1901-2100, Hong Guo

Graduate Theses and Dissertations

Permafrost regions are very sensitive to rapid changes in climate and environment. In recent decades, there has been growing interest to better understand the permafrost degradation over the Northern Hemisphere in the context of human-induced climate change. Understanding permafrost dynamics is not only important for infrastructure but also for environmental protection in cold regions. In-situ permafrost measurements are important for assessing permafrost conditions. However, direct permafrost observations are sparse and asymmetrical in both spatial and temporal coverage. Active layer thickness (ALT) modeling is another approach that can overcome many of these limitations, but the models have large uncertainty in predicting …


Investigating Effects Of Microenvironmental Stress On Cell Metabolism Using Multiphoton Imaging, Lisa Rebello Dec 2021

Investigating Effects Of Microenvironmental Stress On Cell Metabolism Using Multiphoton Imaging, Lisa Rebello

Graduate Theses and Dissertations

Resistance to therapy in cancer is a major cause of poor prognosis in patients. Tumor hypoxia plays an active role in mediating treatment resistance and has been linked to metastases and metastatic potential in cancer. Our research focused on three objectives: i) To understand metabolic effects of chronic and intermittent hypoxia in murine breast cancer cells and its affiliation with metastatic potential ii) To identify the metabolic changes associated with radiation therapy in a panel of radiosensitive and radioresistant human head and neck cancer cells and iii) to monitor the changes in cell metabolism associated with gain of treatment resistance. …


Experimental And Computational Studies Of Electron Rich Alkenes, Alexa May Dec 2021

Experimental And Computational Studies Of Electron Rich Alkenes, Alexa May

Graduate Theses and Dissertations

Thermal homolysis is one of the most fundamental reactions in organic chemistry. Free radical reactions are generally initiated by light or a radical initiator to generate the first radical, which can then propagate or terminate the reaction. Direct thermal homolysis requires no chemical initiators, just an increase in temperature depending on the homolysis energy.There are few studies of direct radical homolysis in complex systems or under mild conditions. The reactions involving C-N homolysis under mild conditions are reported in Chapter 1. Though the authors do not all propose a radical mechanism, we believe they can all be explained by a …


Peer Irrigators And The Choice Of Field Management And Water Control Practices For Irrigation In Arkansas, Victoria Bailey, Kent Kovacs, Christopher Henry, Qiuqiong Huang, Larry J. Krutz Dec 2021

Peer Irrigators And The Choice Of Field Management And Water Control Practices For Irrigation In Arkansas, Victoria Bailey, Kent Kovacs, Christopher Henry, Qiuqiong Huang, Larry J. Krutz

Agricultural Economics and Agribusiness Faculty Publications and Presentations

We examined how irrigation techniques in use by family and friends influence the use and share of land utilizing different irrigation techniques by Arkansas producers. A bivariate sample selection model simultaneously estimated how farm characteristics determine the use and explain the share of a farm that utilizes an irrigation technique. We found that the irrigation techniques in use by family and friends do affect the irrigation techniques a producer uses and the share of acres utilizing different irrigation techniques. A producer with a family or friend that uses end-blocking irrigation is 41% more likely to use end-blocking themselves. Having a …


Listening To Voices Of Latinx Immigrants In Rural America, Jacqueline Smith Dec 2021

Listening To Voices Of Latinx Immigrants In Rural America, Jacqueline Smith

Graduate Theses and Dissertations

The purpose of this phenomenological qualitative study was to capture and gain an understanding of Latinx immigrants’ lived experiences during their transitions from their native countries to rural Arkansas. Using purposeful criterion-based sampling, the population of interest was five Latinx immigrant students and families who migrated from their native countries to the state of Arkansas. The analytic strategy included a single-case model of each family’s transcription, two-case model, cluster analysis to identify likeness, document portrait, and subtheme development. The structural descriptions that formed the essence of the experience resulted in three themes: education, migration, and emotional experiences. The three overall …


Investigation Of Histomoniasis Prevention In Poultry, Lesleigh Beer Dec 2021

Investigation Of Histomoniasis Prevention In Poultry, Lesleigh Beer

Graduate Theses and Dissertations

Histomonas meleagridis is the etiological agent of histomoniasis, also commonly known as blackhead disease. This protozoal disease of poultry is detrimental to turkeys with flock mortalities often reaching 80-100%, although other gallinaceous birds are susceptible. Since the voluntary removal of nitarsone in 2015, the poultry industry is suffering with no approved prophylactics, therapeutics, or vaccines for this disease. The objectives of this dissertation were to evaluate multiple methods for prevention or control of histomoniasis, including dietary chemoprophylaxis and vaccination. Specifically, this research evaluated quinine as a chemoprophylactic candidate (Chapter 3) or live-attenuated H. meleagridis as vaccine candidates (Chapter 4) in …


Effect Of Hydrogen Peroxide On Algae And Microcystin In Control And Lake Waters, Tatiana Castillo Hernandez Dec 2021

Effect Of Hydrogen Peroxide On Algae And Microcystin In Control And Lake Waters, Tatiana Castillo Hernandez

Biological and Agricultural Engineering Undergraduate Honors Theses

Cyanobacteria are photo-autotrophic organisms with a worldwide distribution, which can result in Harmful Algal Blooms (HABs) producing toxins. One of the most common strains of cyanobacteria is Microcystis, which produces the most abundant cyanotoxin, microcystin. In this study, we analyzed the effect of H2O2 on algae and microcystin using both lake and reagent grade water. The first objective was to determine the effect of H2O2 on algae and cyanobacteria in lake water that was nutrient enriched. The second objective was to detect the effect of H2O2 at oxidizing microcystin in …


Effect Of Cyclic Heat Stress On Feeding-Related Hypothalamic Neuropeptides Of Three Broiler Populations And Their Ancestor Jungle Fowl, Giorgio Brugaletta, Elizabeth S. Greene, Travis Tabler, Sara K. Orlowski, Federico Sirri, Sami Dridi Dec 2021

Effect Of Cyclic Heat Stress On Feeding-Related Hypothalamic Neuropeptides Of Three Broiler Populations And Their Ancestor Jungle Fowl, Giorgio Brugaletta, Elizabeth S. Greene, Travis Tabler, Sara K. Orlowski, Federico Sirri, Sami Dridi

Poultry Science Faculty Publications and Presentations

Heat stress (HS) has been increasingly jeopardizing the sustainability of the poultry production. Moreover, modern high-performing chickens are far less able to withstand HS than their predecessors due to higher growth rate and metabolic rates. Performance losses caused by HS are mainly ascribed to decreases in feed consumption. Since feed intake is tightly controlled by the hypothalamic centers of hunger and satiety, we sought to determine the effect of chronic cyclic HS on the expression of feeding-related hypothalamic neuropeptides (FRHN) in unselected chickens (i.e., the ancestor junglefowl—JF) and three broiler lines from diverse stages of genetic selection (i.e., the slow …


Cultural Impact On Identity And How It Is Expressed Through Dress, Jenifer Thao Dec 2021

Cultural Impact On Identity And How It Is Expressed Through Dress, Jenifer Thao

Apparel Merchandising and Product Development Undergraduate Honors Theses

This study examined how students at the undergraduate and graduate levels at the University of Arkansas incorporate their cultural background into their clothing as a form of self-expression. The study included an online survey platform, Qualtrics, created with a series of Likert-type and open-ended response questions to gather data regarding student opinions on clothing impacts. Results indicated that there were no significant associations when it comes to cultural influences on identity and how it is expressed through dress.


Population Connectivity In Voles (Microtus Sp.) As A Gauge For Tall Grass Prairie Restoration In Midwestern North America, Marlis R. Douglas, Steven M. Mussmann, Tyler Chafin, Whitney J.B. Anthonysamy, Mark A. Davis, Matthew P. Mulligan, Robert L. Schooley, Wade Louis, Michael E. Douglas Dec 2021

Population Connectivity In Voles (Microtus Sp.) As A Gauge For Tall Grass Prairie Restoration In Midwestern North America, Marlis R. Douglas, Steven M. Mussmann, Tyler Chafin, Whitney J.B. Anthonysamy, Mark A. Davis, Matthew P. Mulligan, Robert L. Schooley, Wade Louis, Michael E. Douglas

Biological Sciences Faculty Publications and Presentations

Ecological restoration can promote biodiversity conservation in anthropogenically fragmented habitats, but effectiveness of these management efforts need to be statistically validated to determine ’success.’ One such approach is to gauge the extent of recolonization as a measure of landscape permeability and, in turn, population connectivity. In this context, we estimated dispersal and population connectivity in prairie vole (Microtus ochrogaster; N = 231) and meadow vole (M. pennsylvanicus; N = 83) within five tall-grass prairie restoration sites embedded within the agricultural matrix of midwestern North America. We predicted that vole dispersal would be constrained by the …


Mitochondrial Aberrations During The Progression Of Disuse Atrophy Differentially Affect Male And Female Mice, Megan E. Rosa-Caldwell, Seongkyun Lim, Wesley S. Haynie, Jacob L. Brown, David E. Lee, Kirsten R. Dunlap, Lisa T. Jansen, Tyrone A. Washington, Michael P. Wiggs, Nicholas P. Greene Dec 2021

Mitochondrial Aberrations During The Progression Of Disuse Atrophy Differentially Affect Male And Female Mice, Megan E. Rosa-Caldwell, Seongkyun Lim, Wesley S. Haynie, Jacob L. Brown, David E. Lee, Kirsten R. Dunlap, Lisa T. Jansen, Tyrone A. Washington, Michael P. Wiggs, Nicholas P. Greene

Health, Human Performance and Recreation Faculty Publications and Presentations

Background

Disuse decreases muscle size and is predictive of mortality across multiple pathologies. Detriments to mitochondrial function are hypothesized to underlie disuse-induced muscle atrophy. Little data exist on early mechanisms contributing to onset of these pathologies, nor is it known how they differ between sexes. The purpose of this study was to examine differential and conserved responses to mitochondrial quality control in male and female mice during the development and progression of disuse-induced atrophy.

Methods

One hundred C57BL/6J mice (50 male and 50 female) were hindlimb unloaded to induce disuse atrophy for 0 (con), 24, 48, 72, or 168 h. …


Local And Systemic Cytokine, Chemokine, And Fgf Profile In Bacterial Chondronecrosis With Osteomyelitis (Bco)-Affected Broilers, Alison Ramser, Elizabeth Greene, Robert Wideman, Sami Dridi Nov 2021

Local And Systemic Cytokine, Chemokine, And Fgf Profile In Bacterial Chondronecrosis With Osteomyelitis (Bco)-Affected Broilers, Alison Ramser, Elizabeth Greene, Robert Wideman, Sami Dridi

Poultry Science Faculty Publications and Presentations

Complex disease states, like bacterial chondronecrosis with osteomyelitis (BCO), not only result in physiological symptoms, such as lameness, but also a complex systemic reaction involving immune and growth factor responses. For the modern broiler (meat-type) chickens, BCO is an animal welfare, production, and economic concern involving bacterial infection, inflammation, and bone attrition with a poorly defined etiology. It is, therefore, critical to define the key inflammatory and bone-related factors involved in BCO. In this study, the local bone and systemic blood profile of inflammatory modulators, cytokines, and chemokines was elucidated along with inflammasome and key FGF genes. BCO-affected bone showed …


Economic Contribution Of Agriculture And Food To Arkansas’ Gross Domestic Product 1997-2020, Leah English, Jennie Popp, Wayne Miller Nov 2021

Economic Contribution Of Agriculture And Food To Arkansas’ Gross Domestic Product 1997-2020, Leah English, Jennie Popp, Wayne Miller

AAES Research Reports and Research Bulletins

Agricultural production, processing, and retail industries are major contributors to Arkansas’ GDP. Agriculture contributes to the state economy through direct agricultural production, value-added processing, and agricultural retail activities. The Agriculture and Food Sector, which is comprised of agricultural production, processing, and retail industries, promotes economic strength through various interactions with other industries. The use of non-agricultural goods and services as inputs into the agricultural sector promotes diversified growth in Arkansas’ economy and thus plays a vital role in maintaining economic stability throughout the state. This report 1) compares the relative size of the Agriculture and Food Sector in Arkansas with …


Effects Of Herbal Adaptogen Feed-Additive On Growth Performance, Carcass Parameters, And Muscle Amino Acid Profile In Heat-Stressed Modern Broilers, Elizabeth S. Greene, Clay Maynard, Casey M. Owens, Jean-Francois Meullenet, Sami Dridi Nov 2021

Effects Of Herbal Adaptogen Feed-Additive On Growth Performance, Carcass Parameters, And Muscle Amino Acid Profile In Heat-Stressed Modern Broilers, Elizabeth S. Greene, Clay Maynard, Casey M. Owens, Jean-Francois Meullenet, Sami Dridi

Poultry Science Faculty Publications and Presentations

Heat stress has strong adverse effects on poultry production and, thereby, threats its sustainability, which energized scientists to search for innovative and effective solutions. Here, we undertook this study to evaluate the effects of in-feed herbal adaptogen (stress response modifier) supplementation on growth performances, meat quality, and breast amino acid profile in chronic cyclic heat-stressed broilers. Day-old male Cobb 500 chicks (n = 720) were randomly assigned, in environmental chambers (n = 12, 24 pens), to three diet-treatments: a three-phase corn-soybean based diet fed as such (Control, C), or supplemented with the herbal adaptogen at 500 g/1000 kg …


Facile Synthesis Of Tertiary Amine Pendant Polymers By Cu0-Mediated Atrp Under Aqueous Conditions, Collin M. Britten, Kristen Lason, Keisha Walters Nov 2021

Facile Synthesis Of Tertiary Amine Pendant Polymers By Cu0-Mediated Atrp Under Aqueous Conditions, Collin M. Britten, Kristen Lason, Keisha Walters

Chemical Engineering Faculty Publications and Presentations

Cu0-mediated atom transfer radical polymerization (ATRP) in aqueous media is extended to tertiary amine-pendant methacrylate polymers with poly([2-dimethylamino]ethyl methacrylate) (PDMAEMA) serving as a model polymer. By increasing the concentration of deactivating CuII species, reducing the reaction temperature, and increasing the supporting halide concentration to 1 M, polymers with well-defined molecular weight distributions (MWDs) are achieved in under 4 h. MWDs show good agreement with theoretical values, with polydispersity indices (Đ) as low as 1.14. Furthermore, this reaction system shows a remarkable tolerance to dissolved oxygen, with little to no deleterious effects observed for polymerizations run …


Propagation Of A De Novo Gene Under Natural Selection: Antifreeze Glycoprotein Genes And Their Evolutionary History In Codfishes, Xuan Zhuang, C.-H. Christina Cheng Nov 2021

Propagation Of A De Novo Gene Under Natural Selection: Antifreeze Glycoprotein Genes And Their Evolutionary History In Codfishes, Xuan Zhuang, C.-H. Christina Cheng

Biological Sciences Faculty Publications and Presentations

The de novo birth of functional genes from non-coding DNA as an important contributor to new gene formation is increasingly supported by evidence from diverse eukaryotic lineages. However, many uncertainties remain, including how the incipient de novo genes would continue to evolve and the molecular mechanisms underlying their evolutionary trajectory. Here we address these questions by investigating evolutionary history of the de novo antifreeze glycoprotein (AFGP) gene and gene family in gadid (codfish) lineages. We examined AFGP phenotype on a phylogenetic framework encompassing a broad sampling of gadids from freezing and non-freezing habitats. In three select species representing different AFGP-bearing …


Nine-Banded Armadillo (Dasypus Novemcinctus) Activity Patterns Are Influenced By Human Activity, Brett A. Degregorio, Connor Gale, Ellery V. Lassiter, Andrhea Darleen Massey, Caleb P. Roberts, John T. Veon Nov 2021

Nine-Banded Armadillo (Dasypus Novemcinctus) Activity Patterns Are Influenced By Human Activity, Brett A. Degregorio, Connor Gale, Ellery V. Lassiter, Andrhea Darleen Massey, Caleb P. Roberts, John T. Veon

Biological Sciences Faculty Publications and Presentations

As the human footprint upon the landscape expands, wildlife seeking to avoid human contact are losing the option of altering their spatial distribution and instead are shifting their daily activity patterns to be active at different times than humans. In this study, we used game cameras to evaluate how human development and activity were related to the daily activity patterns of the nine-banded armadillo (Dasypus novemcinctus) along an urban to rural gradient in Arkansas, USA during the winter of 2020–2021. We found that armadillos had substantial behavioral plasticity in regard to the timing of their activity patterns; >95% of …


Microbiota From Specific Pathogen-Free Mice Reduces Campylobacter Jejuni Chicken Colonization, Ayidh Almansour, Ying Fu, Tahrir Jatli Alenezi, Mohit Bansal, Bilal Alrubaye, Hong Wang, Xiaolun Sun Nov 2021

Microbiota From Specific Pathogen-Free Mice Reduces Campylobacter Jejuni Chicken Colonization, Ayidh Almansour, Ying Fu, Tahrir Jatli Alenezi, Mohit Bansal, Bilal Alrubaye, Hong Wang, Xiaolun Sun

Poultry Science Faculty Publications and Presentations

Campylobacter jejuni, a prevalent foodborne bacterial pathogen, is mainly transmitted from poultry with few effective prevention approaches. In this study, we aimed to investigate the role of microbiota on C. jejuni chicken colonization. Microbiota from specific pathogen-free (SPF) mouse stools were collected as SPF-Aerobe and SPF-Anaerobe. Birds were colonized with SPF-Aerobe or SPF-Anaerobe at day 0 and infected with C. jejuni AR101 at day 12. Notably, C. jejuni AR101 colonized at 5.3 and 5.6 log(10) C. jejuni CFU/g chicken cecal digesta at days 21 and 28, respectively, while both SPF-Aerobe and SPF-Anaerobe microbiota reduced pathogen colonization. Notably, SPF-Aerobe and SPF-Anaerobe …


Economic And Ghg Emissions Changes Of Aeration And Gypsum Application, Michael Popp, Karen Renee Lindsay, Amanda Ashworth, Philip Moore, Phillip R. Owens, Taylor Adams, Melissa Mccarver, Becky Roark, Dan Pote, John Pennington Nov 2021

Economic And Ghg Emissions Changes Of Aeration And Gypsum Application, Michael Popp, Karen Renee Lindsay, Amanda Ashworth, Philip Moore, Phillip R. Owens, Taylor Adams, Melissa Mccarver, Becky Roark, Dan Pote, John Pennington

Agricultural Economics and Agribusiness Faculty Publications and Presentations

Alternative pasture management strategies are needed to ensure long-term ecological and economical use of abundantly available poultry litter as a source of valuable nitrogen (N), phosphorus (P) and potassium (K). In combination with the common practice of broadcasting poultry litter and soil compaction from equipment and livestock traffic, pasture aeration offers the potential for added soil water penetration and reduced nutrient runoff by creating soil perforations ranging length from 5 to 15 cm using metal spikes that penetrate the soil to 15 cm depth. Also, the addition of gypsum can further reduce P runoff. We evaluate different pasture management scenarios …


Identification Of Genomic Regions Controlling Chalkiness And Grain Characteristics In A Recombinant Inbred Line Rice Population Based On High-Throughput Snp Markers, Yheni Dwiningsih, Anuj Kumar, Julie Thomas, Charles Ruiz, Jawaher Alkahtani, Abdulrahman Al-Hashimi, Andy Pereira Nov 2021

Identification Of Genomic Regions Controlling Chalkiness And Grain Characteristics In A Recombinant Inbred Line Rice Population Based On High-Throughput Snp Markers, Yheni Dwiningsih, Anuj Kumar, Julie Thomas, Charles Ruiz, Jawaher Alkahtani, Abdulrahman Al-Hashimi, Andy Pereira

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Rice (Oryza sativa L.) is the primary food for half of the global population. Recently, there has been increasing concern in the rice industry regarding the eating and milling quality of rice. This study was conducted to identify genetic information for grain characteristics using a recombinant inbred line (RIL) population from a japonica/indica cross based on high-throughput SNP markers and to provide a strategy for improving rice quality. The RIL population used was derived from a cross of “Kaybonnet (KBNT lpa)” and “ZHE733” named the K/Z RIL population, consisting of 198 lines. A total of 4133 SNP markers were used …


Reduced Toxicity Of Centruroides Vittatus (Say, 1821) May Result From Lowered Sodium Β Toxin Gene Expression And Toxin Protein Production, Aimee Bowman, Chloe Fitzgerald, Jeff Pummill, Douglas D. Rhoads, Tsunemi Yamashita Nov 2021

Reduced Toxicity Of Centruroides Vittatus (Say, 1821) May Result From Lowered Sodium Β Toxin Gene Expression And Toxin Protein Production, Aimee Bowman, Chloe Fitzgerald, Jeff Pummill, Douglas D. Rhoads, Tsunemi Yamashita

Biological Sciences Faculty Publications and Presentations

Body tissue and venom glands from an eastern population of the scorpion Centruroides vittatus (Say, 1821) were homogenized and molecular constituents removed to characterize putative sodium beta toxin gene diversity, RT-qPCR, transcriptomic, and proteomic variation. We cloned sodium beta toxins from genomic DNA, conducted RT-qPCR experiments with seven sodium beta toxin variants, performed venom gland tissue RNA-seq, and isolated venom proteins for mass spectrophotometry. We identified >70 putative novel sodium beta toxin genes, 111 toxin gene transcripts, 24 different toxin proteins, and quantified sodium beta toxin gene expression variation among individuals and between sexes. Our analyses contribute to the growing …


Psychobiology Of Stress And Adolescent Depression (Psy Sad) Study: Protocol Overview For An Fmri-Based Multi-Method Investigation, Stassja Sichko, Theresa Q. Bui, Meghan Vinograd, Grant S. Shields, Krishanu Saha, Suzanne Devkota, Hector A. Olvera-Alvarez, Judith E. Carroll, Steven E. Cole, Michael R. Irwin, George M. Slavich Nov 2021

Psychobiology Of Stress And Adolescent Depression (Psy Sad) Study: Protocol Overview For An Fmri-Based Multi-Method Investigation, Stassja Sichko, Theresa Q. Bui, Meghan Vinograd, Grant S. Shields, Krishanu Saha, Suzanne Devkota, Hector A. Olvera-Alvarez, Judith E. Carroll, Steven E. Cole, Michael R. Irwin, George M. Slavich

Psychological Science Faculty Publications and Presentations

Depression is a common, often recurrent disorder that causes substantial disease burden worldwide, and this is especially true for women following the pubertal transition. According to the Social Signal Transduction Theory of Depression, stressors involving social stress and rejection, which frequently precipitate major depressive episodes, induce depressive symptoms in vulnerable individuals in part by altering the activity and connectivity of stress-related neural pathways, and by upregulating components of the immune system involved in inflammation. To test this theory, we recruited adolescent females at high and low risk for depression and assessed their psychological, neural, inflammatory, and genomic responses to a …


Thin Safety Margin: The Sefor Super-Prompt-Critical Transient Experiments, Ozark Mountains, Arkansas 1970–1971, Jerry Havens, Collis Geren Oct 2021

Thin Safety Margin: The Sefor Super-Prompt-Critical Transient Experiments, Ozark Mountains, Arkansas 1970–1971, Jerry Havens, Collis Geren

Arkansas Scholarly Editions

Thin Safety Margin charts the history of SEFOR, a twenty-megawatt reactor that operated for three years in the rural Ozark Mountains of Arkansas as part of an internationally sponsored program designed to demonstrate the Doppler effect in plutonium-oxide-fueled fast reactors. Authors Jerry Havens and Collis Geren draw upon this history to assess the accidental explosion risk inherent in using fast reactors to reduce the energy industry’s carbon dioxide emissions.

If a sufficiently powerful fast-neutron explosion were to cause the containment of a reactor such as SEFOR’s to fail, the reactor’s radiotoxic plutonium fuel could vaporize and escape into the surrounding …


Central Nervous System Associated With Light Perception And Physiological Responses Of Birds, Seong Kang Oct 2021

Central Nervous System Associated With Light Perception And Physiological Responses Of Birds, Seong Kang

Poultry Science Faculty Publications and Presentations

Environmental light that animal receives (i.e., photoperiod and light intensity) has recently been shown that it affects avian central nervous system for the physiological responses to the environment by up or downregulation of dopamine and serotonin activities, and this, in turn, affects the reproductive function and stress-related behavior of birds. In this study, the author speculated on the intriguing possibility that one of the proposed avian deep-brain photoreceptors (DBPs), i.e., melanopsin (Opn4), may play roles in the dual sensory-neurosecretory cells in the hypothalamus, midbrain, and brain stem for the behavior and physiological responses of birds by light. Specifically, the author …


Evaluating The Bioenergetics Health Index Ratio In Leigh Syndrome Fibroblasts To Understand Disease Severity, Ajibola B. Bakare, Joseph Dean, Qun Chen, Vedant Chen, Yimin Huang, Thomas Laframboise, Edward J. Lesnefsky, Shilpa Iyer Oct 2021

Evaluating The Bioenergetics Health Index Ratio In Leigh Syndrome Fibroblasts To Understand Disease Severity, Ajibola B. Bakare, Joseph Dean, Qun Chen, Vedant Chen, Yimin Huang, Thomas Laframboise, Edward J. Lesnefsky, Shilpa Iyer

Biological Sciences Faculty Publications and Presentations

Several pediatric mitochondrial disorders, including Leigh syndrome (LS), impact mitochondrial (mt) genetics, development, and metabolism, leading to complex pathologies and energy failure. The extent to which pathogenic mtDNA variants regulate disease severity in LS is currently not well understood. To better understand this relationship, we computed a glycolytic bioenergetics health index (BHI) for measuring mitochondrial dysfunction in LS patient fibroblast cells harboring varying percentages of pathogenic mutant mtDNA (T8993G, T9185C) exhibiting deficiency in complex V or complex I (T10158C, T12706C). A high percentage (>90%) of pathogenic mtDNA in cells affecting complex V and a low …