Digital Commons Network^™

Oxidation Of Thrombomodulin Methionine 388 In Cigarette Smokers, Samrat B. Thapa

Graduate Theses and Dissertations

This work tested the hypothesis that oxidation of methionine 388 in thrombomodulin is higher in cigarette smokers, and thus a likely contributor towards the hypercoagulable state in smokers. Thrombomodulin, a protein cofactor found on endothelial cell surfaces, regulates the activity of thrombin. Thrombin bound to thrombomodulin no longer converts fibrinogen to fibrin, but instead activates Protein C which, in turn, stops the coagulation cascade by inactivation of clotting factors. The oxidation of methionine 388 of thrombomodulin has been shown in vitro to dramatically decrease the anticoagulant cofactor activity of thrombomodulin. The blood of cigarette smokers is more prone to clot …

New Mexico Tourism: Conflict And Cooperation In The Land Of Enchantment, Emily Alyce Bullington

Graduate Theses and Dissertations

The purpose of this study is to analyze the impact that tourism and tourist sites have upon the surrounding communities in New Mexico. It will look specifically at Bandelier National Monument, El Santuario de Chimayo, and the International UFO Museum and Research Center in Roswell. These sites have all been the cause of tensions in their interactions with the local communities, over issues of culture, identity, or resource usage. But these tourist attractions have also brought economic stimulus to these areas, which has brought about a need for cooperation and compromise between the groups as they have negotiated how tourism …

Effects Of Ergot Alkaloids And Bovine Bodily Fluids On Cytochrome P450 Activity, Nicholas Scott Ezell

Graduate Theses and Dissertations

This thesis evaluates the Promega^TM P450-Glo assay (Promega^TM V9800) as a tool for quantifying ergot alkaloid concentration. Current techniques used for detection of ergot alkaloids are slow and expensive, do not detect all ergot alkaloids, or are not effective on bovine bodily fluids. The first study was conducted to determine effects of commercial ergot alkaloids (n = 6; 0 - 400 μM) on the Promega^TM P450-Glo assay. Cytochrome P450 (CYP450) activity in assay had a differential response to each ergot alkaloid and concentration. As concentrations of ergotamine, dihydroergotamine, ergocornine, and ergocryptine increased CYP450 activity was inhibited (P …

Efficacy Of Probiotics For Reducing The Incidence Of Lameness In Broilers Grown On Wire Flooring, John Matthew Stark

Graduate Theses and Dissertations

Growing broilers on wire flooring provides an excellent experimental model for reproducibly triggering significant levels of lameness. In Pilot Study #1 using broilers from Line C grown on wire flooring, adding the Biomin probiotic PoultryStar® to the feed reduced the percentage of lameness by half when compared with broilers that received the control diet alone. In Pilot Study # 2 using broilers from Line B grown on wire flooring, adding the PoultryStar® probiotic reduced the percentage of lameness to 8% when compared with 28% lameness in broilers that received the control diet alone. The objective of this study was to …

Efficacy Of Selected Disinfectants Against Salmonella Isolates From Broiler Breeders, Arslan Aslam

Graduate Theses and Dissertations

Salmonella have been causing huge losses in the poultry industry and have been a major cause food borne illness for many years. Salmonella infections in humans from poultry have been increasing. Good hygiene and biosecurity measures can reduce the incidence of Salmonella infections at poultry farms. Disinfection is a most important measure taken to prevent Salmonellosis in poultry. This research was conducted to determine the efficacy of 12 disinfectants against seven Salmonella isolates in the presence and absence of organic matter. A bacterial solution of a specific optical density value was prepared and .05x, .1x and .2x concentrations of disinfectants …

Genetic Structure Of The Copperhead (Viperidae: Agkistrodon Contortrix Mokasen) At Its Most Northern Distribution, Brenna Aaren Levine

Graduate Theses and Dissertations

The focus of molecular studies in North American pitvipers has been on species that warrant conservation concern, such as Timber (Crotalus horridus) and Massasauga rattlesnakes (Sistrurus catenatus). Scant effort has been directed towards the molecular ecology of the Copperhead (Agkistrodon contortrix), other than to evaluate male reproduction in a laboratory setting and phylogenetic history. Thus, employing DNA-based molecular techniques to study the natural history of A. contortrix will broaden our knowledge of molecular ecology in North American pitvipers, and particularly in a non-threatened species that can serve as a surrogate for threatened and endangered …

An Analysis Of Firearms Training Performance Among Active Law Enforcement Officers, John Thomasson

Graduate Theses and Dissertations

Firearms proficiency is an implicit expectation, held by the public of police officers, due to presumption that the required firearm training is an adequate preparation for a deadly force encounter. However, anecdotal evidence and available data on police shootings suggest that conventional, unrealistic training methods are wholly inadequate. To present stress into firearms training, some departments have opted for exercises such as physical exertion and shoot-house training as a substitute for realistic simulation of force-on-force confrontations.

To determine whether such exercises are comparable, an observation of performance and heart rate levels was conducted on a group of eight police officers, …

Evaluating The Formation Of Bacterial Chondronecrosis With Osteomyelitis In Broilers Raised On Portable Wire Floor Models, Alex David Gilley

Graduate Theses and Dissertations

Rearing birds on wire flooring has proven to be an effective method for consistently triggering significant levels of lameness in broilers, and while the wire flooring model has been proven effective, more mobile wire floor models have been developed to compliment the facility management conditions within commercial genetic selection programs. The mobile wire floor models have been titled "speed bumps", and through previous evaluation have resulted in significantly higher levels of lameness in broilers compared to litter floor shavings. The current experiment contains two studies (studies 1 and 2). Both studies involved comparing leg weakness between broiler strains; while in …

Extraction And Purification Of Gamma-Tocotrienol From Rice Bran Oil Deodorizer Distillate, Mary Kordsmeier

Graduate Theses and Dissertations

The tocols (alpha-, beta-, gamma- and delta- tocopherols (T); alpha-, beta-, gamma- and delta-tocotrienols (T3)) make up the vitamin E family of antioxidants. Tocols have many health benefits. Gamma-T3 has been shown to protect against harmful radiation effects in mice. During rice bran oil refining up to 90% of tocols in rice bran are lost to the deodorizer distillate. The objective of this study was to optimize parameters for analyzing and isolating tocols from rice bran oil deodorizer distillate (RBODD). NP-HPLC analysis of tocol standards was optimized by testing ten mobile phases. Tocol extraction was optimized by testing three concentration …

Influence Of Horn Flies And Breed Type On Milk Production, Calf Production Traits, Pasture Behavior, And Temperament Measurements In Beef Cattle, Angela Rene Mays

Graduate Theses and Dissertations

An experiment conducted in El Reno, Oklahoma during the fly season (May - September/October) evaluated the effects of horn flies on milk production, calf performance, and pasture behavior and temperament measurements of beef cow calf pairs. Cows (n = 53) sired by Bonsmara (BONS; n = 7), Brangus (BRAN; n = 13), Charolais (CHAR; n = 8), Gelbvieh (GELV; n = 5), Hereford (HERF; n = 12), and Romosinuano (ROMO; n = 8) from Brangus dams and their Angus sired calves (n = 51) were used in the study. Horn fly counts (HFC) and milk yield and quality estimates were …

After Orwell: Totalitarian Fears And The English Political Novel, 1950-2010, Jackson Ayres

Graduate Theses and Dissertations

After Orwell: Totalitarian Fears and the English Political Novel, 1950-2010 gives a coherent account of the English political novel after World War II, a critical narrative absent from current scholarship. I contend that George Orwell's Nineteen Eighty-Four (1949), a touchstone for political fiction, is underwritten by Orwell's conflicted attitude toward politics: despite embracing politics as the necessary means to genuinely improve people's lives, he also remained suspicious of politics' apparently inherent potential to diminish or even eliminate autonomy. Orwell's simultaneous attraction and vigorous resistance to politics, I argue, is tied to broader contemporaneous anxieties over political and cultural totalization. Such …

New Effects Of Aging And Lattice Intercalation On Surface Properties Of Titanate Nanobelts, Roger Williams

Graduate Theses and Dissertations

Titanate nanobelts (NBs) have structural characteristics beyond that of clays. Due to a negatively charged lattice matrix of edge-shared TiO6-octahedra, the location of intercalated cations within the interlayer space may dictate the charge-conductions. This environment may in turn govern the lattice-framework's stability and surface properties, based upon our preliminary

data.

On that basis, these nanomaterials have been found in our lab to possess superb biological compatibility that is closely related to the types of the intercalated cations. In addition, a prolonged agitation was proven to enable us to manipulate the titanate NBs' length. In a parallel study, a ripening was …

Learning Experiences And Perspective Transformation In Evangelical Faith-Based Adult Nonformal Education Programs, Philip Gerke

Graduate Theses and Dissertations

The study adapted an existing instrument to examine perspective transformation and its associated factors in participants of evangelical faith-based adult nonformal education in the Midwestern United States. Stratified random one-stage cluster sampling of 11 churches produced a nonprobability sample (N = 597) that was significantly (p < .05) different from the population of the geographical location of the study. An 86% majority self-reported a level of agreement or stronger of perceived transformation of perspectives, but differences predicted by gender were insignificant. The difference in perceived perspective transformations between respondents aged 40-59 that had the highest levels and respondents aged 60 and above that had the lowest levels was significant. The factors of influential individuals, personal reflection, and thought-provoking learning assignments significantly predicted all four factors of perspective transformation; the Writing Assignment factor was a significant negative predictor of only the Perception of Change factor, and a significant positive predictor of only the Future Benefits factor. The study recommended that additional research on faith-based frames of reference and age category differences. The study also recommended that faith-based practitioners consider emphasizing transformative learning experiences and personal reflection in their programs for adults.

The Life History Of Larinus Minutus, A Biological Control Agent Of Invasive Knapweeds, And Its Dispersal From Release Sites In Arkansas, Adam M. Alford

Graduate Theses and Dissertations

Larinus minutus Gyllenhal, a biological control agent of invasive knapweeds, has become established in several states and provinces since initial North American introduction in 1991. In order to reduce growing spotted knapweed populations in Northwest Arkansas, Larinus minutus (a biological control agent of spotted knapweed) was released annually from 2008-2011. Little is known about the larval development of this species, although the widespread use of this insect has provided research describing detailed host range and generalized life history. The speed and extent of the spread of this weevil from release sites following introduction have not been reported. This research described …

Effects Of Using Canola Meal As A Protein Source In Broiler Diets, Charles Danny Bradley Jr

Graduate Theses and Dissertations

Six experiments were conducted to evaluate the response of broilers fed canola meal. Experiment 1 assessed performance and carcass yields when broilers were fed various combinations of canola and soybean meal in nutritionally balanced diets based on digestible amino acid values. The results suggested that canola meal can be used in isocaloric diets as a partial replacement for Soybean meal.

Experiment 2 assessed broiler performance and carcass yields when using various levels of canola meal in broiler diets with a constant level of supplemental poultry oil. The resulting data suggested when diets are formulated with a constant level of supplemental …

Resources And Relationships: Food Insecurity And Social Capital Among Middle School Students, Don Edward Willis

Graduate Theses and Dissertations

This study examines the relationship between food insecurity and Social capital among 5th-7th graders attending an intermediate school in Northwest Arkansas where nearly 70 percent of students participate in the free or reduced lunch program. The central research questions are: Does Social capital have a direct impact on children's food insecurity? And, does Social capital mediate the influence of negative circumstances on children's food insecurity? This study finds that Social capital does have a significant association with food insecurity, even when controlling for multiple demographic and circumstantial factors. However, there appears to be no mediation of circumstance by Social capital. …

Qcm Aptasensor For Rapid And Specific Detection Of Avian Influenza Virus, Luke Brockman

Graduate Theses and Dissertations

There has been a need for rapid detection of avian influenza virus (AIV) H5N1 due to it being a potential pandemic threat. Most of the current methods, including culture isolation and PCR, are very sensitive and specific but require specialized laboratories and trained personnel in order to complete the tests and are time-consuming. The goal of this study was to design a biosensor that would be able to rapidly detect AIV H5N1 using aptamers as biosensing material and a quartz crystal microbalance (QCM) for transducing method. Specific DNA aptamers against AIV H5N1 were immobilized, through biotin and streptavidin conjugation, onto …

Relationship Of Lactate Dehydrogenase & Prolactin Genotypes To Immune Function, Growth, And Composition Of Replacement Heifers Grazing Tall Fescue, Christina Marie Turner

Graduate Theses and Dissertations

Objectives of this research were to determine effects of LDH enzymatic activity and circulating PRL on immune response, growth, composition, and reproduction, and to determine the effects of single nucleotide polymorphisms of LDH and PRL on immune function, growth and carcass traits, cyclicty, and fecundity of replacement heifers grazing endophyte infected tall fescue. Eighty-nine Angus based heifers had physical and ultrasound measurements along with blood samples collected at weaning, yearling, and prebreeding. Estrus detection was conducted for 10 d post each collection period, except prebreeding. Pregnancy status was verified after AI and again after bull removal. Heifers were maintained on …

Development Of A Predictive Modeling System For Validation Of The Cumulative Mirobial Inactivation Of The Salmonellae In Pepperoni Utilizing A Non-Pathogenic Surrogate Microorganism (Enterococcus Faecalis), Scott Donald Stillwell

Graduate Theses and Dissertations

Salmonellosis is the most frequently occurring bacterial foodborne illness in the United States and the human case rate has not improved for the past two decades. The federal agency responsible for oversight of meat and poultry processors has announced the intent to extend existing pathogen reduction performance standards for Salmonella spp. to cover all classes of products including fermented sausages that are currently produced under HACCP plans that are validated for control of Escherichia coli O157:H7. The proposed regulatory modifications will require processors to revalidate HACCP plan controls to achieve either a 6.5 or a 7.0 log10 inactivation of the …

Ecology And Flock-Following Behavior Of The Wedge-Billed Woodcreeper In Eastern Ecuador, Abigail Darrah

Graduate Theses and Dissertations

The wedge-billed woodcreeper (Glyphorynchus spirurus) is a common understory suboscine passerine of lowland Neotropical rainforests. It frequently joins mixed-species understory flocks but also regularly forages alone, and thus is an excellent model species on which to conduct comparative behavioral observations to examine the hypothesized costs and benefits of flock-following. Individuals exhibit variable flocking propensities (proportion of time spent with flocks), and thus observing the correlations between flocking propensity and physical and environmental factors can provide further insight into the importance of flock-following to the ecology of this species. Despite its abundance at many sites and its wide geographic range, surprisingly …

Development Of A Pdms Based Micro Total Analysis System For Rapid Biomolecule Detection, Balaji Srinivasan Venkatesh

Graduate Theses and Dissertations

The emerging field of micro total analysis system powered by microfluidics is expected to revolutionize miniaturization and automation for point-of-care-testing systems which require quick, efficient and reproducible results. In the present study, a PDMS based micro total analysis system has been developed for rapid, multi-purpose, impedance based detection of biomolecules. The major components of the micro total analysis system include a micropump, micromixer, magnetic separator and interdigitated electrodes for impedance detection. Three designs of pneumatically actuated PDMS based micropumps were fabricated and tested. Based on the performance test results, one of the micropumps was selected for integration. The experimental results …

Genetic Analysis Of The Promoter Region Of The Serotonin Receptor 5ht2b And Its Contribution To Pulmonary Hypertension Syndrome In Broiler-Type Chickens, Khaloud Awada Alzahrani

Graduate Theses and Dissertations

Pulmonary Arterial Hypertension (PAH) is a sever disorder characterized by high pulmonary artery pressure and pulmonary vascular resistance along with specific histological changes. Idiopathic PAH is a human disease of unknown origin that showed common characteristics to PHS/ascites in chicken. PHS/ascites is a condition found in broilers causing right ventricular hypertrophy, valvular insufficiency, increased venous pressure, variable liver changes, accumulation of fluids in the abdominal cavity, and finally lung and heart failure. Currently, there is no acceptable animal model for human PAH. Our group has been validating the chicken as the medical animal model for human PAH, thus we have …

Journal Of Food Law & Policy - Spring 2013, Journal Editors

Journal of Food Law & Policy

No abstract provided.

The Forgotten Half Of Food System Reform: Using Food And Agricultural Law To Foster Healthy Food Production, Emily Broad Leib

Journal of Food Law & Policy

America is facing widespread problems with its food system, including environmental harms due to externalities from industrial farms; the increasing amount of "food _miles" traveled by the products that make up our daily meals; and the growing size and complexity of recent outbreaks of foodborne illnesses. Indeed, the entire system that covers the life cycle of food, through production, processing, distribution, consumption, and food waste management, is in crisis. One of the most disturbing of these well-documented problems with the industrial food system is the increase in rates of obesity and diet-related illnesses. Obesity rates in the U.S. have more …

An Overview Of Arkansas' Right-To-Farm-Law, L. Paul Goeringer, H. L. Goodwin

Journal of Food Law & Policy

In the 1980s, state legislatures in all fifty states enacted statutes commonly referred to as "right-to-farm" laws. Arkansas enacted its right-to-farm law ("the Act") in 1981. While there are similarities, these laws differ from state-to-state. All right-to-farm laws provide agricultural producers with statutory defenses to nuisance challenges, subject to certain conditions. As one scholar has noted, right-to-farm laws are designed "to protect existing farm investments by reducing actions under nuisance law that enjoined agricultural activities." These laws also work to preserve farmland and protect established farmland from the pressures of urbanization, allowing "farmers to continue with their husbandry pursuits rather …

The U.S. Department Of Agriculture As A Public Health Agency? A "Health In All Policies" Case Study, Lindsay F. Wiley

Journal of Food Law & Policy

The "war on obesity" is now well into its second decade. What began as an effort to encourage medical doctors to screen and treat patients whose weight put them at risk for health problems has transformed into a much broader public health campaign to address the root causes of obesity. A growing number of state, territorial and local health departments are currently exploring new ways to promote healthy eating and physical activity. At the federal level, the U.S. Centers for Disease Control and Prevention (CDC) has made "nutrition, physical activity and obesity" a top priority.

Molecular Diagnosis Of Metabolic Fast Growth Related Diseases In Broiler, Adnan Ali Khalaf Al-Rubaye

Graduate Theses and Dissertations

Pulmonary Hypertension Syndrome (PHS) and lameness are important metabolic diseases that affect rapidly growing broilers. The research reported in the first section of this dissertation focused on developing qPCR assays to identify differences in the expression levels of four candidate genes possibly associated with PHS: angiotensin II type 1 receptor (AGTR1): urotensin receptor 2D (UTS2D); serotonin receptor/transporter type 2Bn (HTR2B); and angiotensinogen cleaving enzyme (ACE). Expression levels of these candidate genes were examined in four different tissues. We established ribosomal protein S14 (RPS14) and RNA polymerase subunit 2B (RP2B) as suitable reference genes because they showed the most consistent deltaCt …

Considering Kranzhügeln: An Exploration Into The Structural Variation And Environmental/Spatial Distribution Of The Third Millennium "Kranzhügel" Sites, Elise Jakoby

Graduate Theses and Dissertations

First named by von Oppenheim over a century ago, the distinctive third millennium BC kranzhügeln, or "wreath-mound," sites of the Syrian Desert remain a poorly understood phenomenon. While archaeological investigations have been undertaken at a handful of kranzhügel-like sites including Tell Chuera, Tell al-Rawda, and Tell Beydar, the overall number, geographic distribution, and morphological variation of so-called "kranzhügel" sites remains largely unexplored.

1960s-era CORONA satellite imagery available through the CORONA Atlas Project (http://corona.cast.uark.edu/) now enables more systematic documentation of the kranzhügel sites and the production site-scale visual and quantitative analysis. Analysis of kranzhügel distribution and morphology …

Comparing Decellularized Muscle Tissue With An Engineered Muscle Biomaterial, Katelin Cherry

Biomedical Engineering Undergraduate Honors Theses

Decellularized tissues composed of extracellular matrix are commonly used for tissue transplantations but this method has many limitations. An alternative approach is to create an extracellular matrix by seeding degradable foams with cells, culturing these foams to allow extracellular matrix to be secreted from the cells, then washing away the degradable foam to collect the material that is produced. This study was interested in comparing decellularized skeletal muscle tissue to an engineered biomaterial that was seeded with skeletal muscle myoblast cells. Collagen content of decellularized tissue and engineered biomaterial were quantified using a hydroxyproline assay to compare the two samples. …

Animal Science E-Newsletter, May 2013, University Of Arkansas, Fayetteville. Department Of Animal Sciences

Animal Science e-Newsletter

No abstract provided.