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Uab Department Of Music Presents Fall 2025 Performance Calendar, Shannon Thomason Sep 2025

Uab Department Of Music Presents Fall 2025 Performance Calendar, Shannon Thomason

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No abstract provided.


September 26, 2025 Ereporter, University Of Alabama At Birmingham Sep 2025

September 26, 2025 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


“Who All Gon Be There”: The Relationship Between Racial Identity, Perceived Social Distance, And Anxiety Among People Of African Descent, Veronica R. Mixon Sep 2025

“Who All Gon Be There”: The Relationship Between Racial Identity, Perceived Social Distance, And Anxiety Among People Of African Descent, Veronica R. Mixon

All ETDs from UAB

Mental health disparities among people of African descent are an important public health issue within the US. During COVID, between 2020 and 2021, anxiety symptoms among African American adults increased, which led to an overall increase in anxiety and depression rates (Vahratian et al., 2021; CDC, 2023). Despite this increase, only 39% of African Americans who experience mental health difficulties, receive treatment. The pandemic made it difficult for people to come together and there were heightened experiences of racial distress due to the events surrounding George Floyd. Prior research has shown that experiences of racism, isolation, and cultural disconnection have …


Equal Access Birmingham To Host Annual Heart + Sole 5k, Micah Hardge Sep 2025

Equal Access Birmingham To Host Annual Heart + Sole 5k, Micah Hardge

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No abstract provided.


Canceled: Free Lecture By Renowned Playwright, Poet Dan O'Brien At Uab, Tehreem Khan Sep 2025

Canceled: Free Lecture By Renowned Playwright, Poet Dan O'Brien At Uab, Tehreem Khan

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No abstract provided.


September 24, 2025 Blazer Weekly, University Of Alabama At Birmingham Sep 2025

September 24, 2025 Blazer Weekly, University Of Alabama At Birmingham

Blazer Weekly (student newsletter)

No abstract provided.


September 23, 2025 Ereporter, University Of Alabama At Birmingham Sep 2025

September 23, 2025 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


Uab's Aeiva Presents Nationally Touring Exhibition 'Young, Gifted And Black: The Lumpkin Boccuzzi Family Collection Of Contemporary Art', Shannon Thomason Sep 2025

Uab's Aeiva Presents Nationally Touring Exhibition 'Young, Gifted And Black: The Lumpkin Boccuzzi Family Collection Of Contemporary Art', Shannon Thomason

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No abstract provided.


September 19, 2025 Ereporter, University Of Alabama At Birmingham Sep 2025

September 19, 2025 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


September 17, 2025 Blazer Weekly, University Of Alabama At Birmingham Sep 2025

September 17, 2025 Blazer Weekly, University Of Alabama At Birmingham

Blazer Weekly (student newsletter)

No abstract provided.


September 16, 2025 Ereporter, University Of Alabama At Birmingham Sep 2025

September 16, 2025 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


Oct. 9, "Arrival From Sweden: The Music Of Abba" Live At Uab's Alys Stephens Center, Shannon Thomason Sep 2025

Oct. 9, "Arrival From Sweden: The Music Of Abba" Live At Uab's Alys Stephens Center, Shannon Thomason

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No abstract provided.


Structural Analysis Of Pseudomonas Phage Dev Virion-Associated Rna Polymerase (Gp71), James Scherer Sep 2025

Structural Analysis Of Pseudomonas Phage Dev Virion-Associated Rna Polymerase (Gp71), James Scherer

All ETDs from UAB

DEV is a Pseudomonas aeruginosa bacteriophage part of a newly reclassified genus called Schitoviridae. This group of bacteriophages is also referred to as “N4-like” phages, after the prototypical Escherichia coli phage N4, originally isolated from sewage water in 19661. N4, and other phages in the group, contain a large, virion-associated RNA polymerase (vRNAP). This vRNAP is vital to the proliferation of the phage, as it performs the transcription of the early gene products and potentially acts as a motor that helps eject the viral genome into the host bacteria. In DEV, the vRNAP is also known as gene product 71 …


September 12, 2025 Ereporter, University Of Alabama At Birmingham Sep 2025

September 12, 2025 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


Financial Outcomes In Value-Based Care: A Comparative Claims-Based Study Of Medicare Advantage Patients In Investor-Backed Primary Care Practices Pre/Post Investment, Aaron Mark Bujnowski Sep 2025

Financial Outcomes In Value-Based Care: A Comparative Claims-Based Study Of Medicare Advantage Patients In Investor-Backed Primary Care Practices Pre/Post Investment, Aaron Mark Bujnowski

All ETDs from UAB

Medicare Advantage (MA) plans are value-based care (VBC) models aimed at improving cost and quality through prevention to counter the traditional fee-for-service (FFS) Medicare care model, which disincentivizes preventive care and risks misuse and overutilization. Some primary care practices purporting VBC capabilities have attracted private capital investors, yet whether external investment improves cost outcomes has not yet been definitively established. This dissertation examines whether investor-backed primary care organizations participating in MA demonstrate statistically significant reductions in per-patient, per-year claims costs after investment for seven ambulatory care–sensitive conditions. The study applies two-way fixed-effects regression models to a sample of 98,014 patient-year …


Moving Beyond M1/M2: Xenoline-Polarized Macrophages As A Physiologically Relevant Model Of Tumor-Associated Macrophages In Glioblastoma, Hasan Alrefai Sep 2025

Moving Beyond M1/M2: Xenoline-Polarized Macrophages As A Physiologically Relevant Model Of Tumor-Associated Macrophages In Glioblastoma, Hasan Alrefai

All ETDs from UAB

Glioblastoma (GBM) remains one of the most treatment-refractory cancers, with few therapeutic advances translating into survival benefit. With a median survival of just 15-18 months, the need for effective therapies is urgent. A key obstacle is the underutilization of tumor-associated macrophages (TAMs) in preclinical models. TAMs account for a sizable proportion of GBM by mass and drive malignant behaviors such as angiogenesis, invasion, and resistance to chemoradiotherapy, making them attractive therapeutic targets. Unfortunately, most in vitro GBM-TAM models are inadequate, as they fail to capture the cellular heterogeneity and microenvironmental interactions that drive tumor progression, therapeutic resistance, and immune evasion. …


Probiotic Biogeography In The Neonatal Intestine, Sierra Hansen Sep 2025

Probiotic Biogeography In The Neonatal Intestine, Sierra Hansen

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Neonatal infection remains a leading cause of both neonatal morbidity and mortality worldwide, particularly in preterm infants. Probiotic bacteria have been demonstrated to protect against the development of neonatal intestinal dysbiosis, however, formulations and efficacy vary substantially, highlighting a critical gap in the current understanding of the mechanisms governing probiotic efficacy in this population. This gap is exacerbated by regulatory standards which favor economic expansion over scientific rigor. Furthermore, current studies on probiotic efficacy largely rely on indirect or relative readouts of intestinal bacterial burden. Herein, we directly quantify the probiotic effects of Ligilactobacillus murinus V10 and Escherichia coli Nissle …


Lineage-Associated Zinc Metalloprotease B And Its Impact On Cardiac Damage Elicited During Invasive Pneumococcal Disease, Jennifer Nichelle Luck Sep 2025

Lineage-Associated Zinc Metalloprotease B And Its Impact On Cardiac Damage Elicited During Invasive Pneumococcal Disease, Jennifer Nichelle Luck

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During invasive disease, certain strains of Streptococcus pneumoniae (Spn) can invade the myocardium, damaging cardiomyocytes and predisposing patients to life-threatening cardiac complications. To identify genetic loci involved in pneumococcal cardio-virulence, we performed a bacterial genome-wide association study using 825 genomes corresponding to 17 distinct Spn lineages associated with varying rates of cardiac complications during hospitalization for pneumonia. This led to the identification of an allele of zmpB, the gene encoding Zinc metalloprotease B (ZmpB). Infection of mice with a ZmpB deficient mutant, i.e., TIGR4ΔzmpB, found that ZmpB was required to form foci of infection in the heart, i.e., cardiac microlesions. …


Understanding Psychotic Disorders Using Normative Modeling-Derived Individual-Level Brain Structural Abnormalities, Natalie Remiszewski Sep 2025

Understanding Psychotic Disorders Using Normative Modeling-Derived Individual-Level Brain Structural Abnormalities, Natalie Remiszewski

All ETDs from UAB

Psychosis is an heterogenous condition that occurs in many psychiatric disorders. It has a variable symptom presentation and recent initiatives have suggested that investigating the underlying neurobiology of psychiatric disorders rather than their symptomatology would provide a more accurate picture for diagnosis, prognosis, and treatment. Grey matter has been implicated in the pathophysiology of psychosis and psychotic disorders, though significant natural variation due to age and sex have impeded the distinction of pathologically relevant grey matter abnormalities in psychosis. Additionally, case-control approaches to exploring grey matter abnormalities in psychotic disorders often obscure subtle variation in individuals. Here, we utilize a …


Effects Of Probiotic Lactobacilli On Streptococcus Mutans: Implications For Early Childhood Caries, Walaa Al-Turki Sep 2025

Effects Of Probiotic Lactobacilli On Streptococcus Mutans: Implications For Early Childhood Caries, Walaa Al-Turki

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Effects of Probiotic Lactobacilli on Streptococcus mutans: Implications for Early Childhood Caries WALAA MOHIEDEN AL TURKI DENTISTRY ABSTRACT Purpose: Probiotic Lactobacillus species have been shown to have beneficial effects against early childhood caries (ECC) by inhibiting the growth of cariogenic bacteria. However, the acidogenicity of Lactobacillus spp. could have potential carcinogenic effect. The objective of this study was to investigate the effects of probiotic lactobacilli and cariogenic lactobacilli on the growth, biofilm formation, and acid production of Streptococcus mutans (S. mutans). Methods: Growth competition between probiotic L. rhamnosus GG (L-GG) or caries-associated L. rhamnosus M72-26 (L-M72) and S. mutans UA159 …


Bayesian Survival Analysis For High-Dimensional Compositional Data, Zhenying Ding Sep 2025

Bayesian Survival Analysis For High-Dimensional Compositional Data, Zhenying Ding

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Survival analysis integrating microbiome and clinical data offers powerful insights into human health. The microbiome influences immunity, inflammation, and cancer outcomes. Combining microbial profiles with clinical factors like tumor stage, treatment, and demographics enhances understanding of how host-microbe interactions affect survival. To analyze these complex datasets, advanced statistical methods, including Bayesian models, penalized Cox proportional hazards models, and machine learning techniques are employed. These approaches can uncover novel biomarkers and therapeutic targets, leading to personalized treatment strategies that optimize patient survival. However, challenges arise due to the compositionality, high-dimensionality, and phylogenetic relation between taxa in microbiome data. In this dissertation, …


Identifying Functional Regional Changes In Patients With Parkinson’S Disease And Freezing Of Gait, Taylor Robin Davis Sep 2025

Identifying Functional Regional Changes In Patients With Parkinson’S Disease And Freezing Of Gait, Taylor Robin Davis

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Freezing of gait (FOG) affects anywhere from 20-80% of those with Parkinson’s Disease (PD) with the prevalence increasing with disease severity and length. This detrimental symptom is unpredictable and poorly characterized, which adds to the negative experience of FOG as it is difficult to treat. Using resting-state fMRI (rs-fMRI), we set out to determine the functional changes in those with PD-FOG and map onto regions of the brain where signal power, measured using fractional amplitude of low-frequency fluctuations (fALFF), synchronicity, as measured by regional homogeneity (ReHo), and strength and direction of intra-network connections as measured by static effective connectivity, are …


Temperature-Dependent Sex Determination: Implications For The Ecology, Evolution, And Conservation Of Sea Turtles, Forrest William Collins Sep 2025

Temperature-Dependent Sex Determination: Implications For The Ecology, Evolution, And Conservation Of Sea Turtles, Forrest William Collins

All ETDs from UAB

For reptiles, their method of sex determination is temperature-dependent sex determination (TSD). This is where the environmental temperature directly influences the sex ratio being produced within a clutch. For sea turtles, sex is determined within a thermosensitive period (TSP) in which incubation temperatures will result in either males (cooler), females (warmer), or 50:50 even sex ratio. For this dissertation, 2 species of sea turtles were evaluated for their TSD and its implications on their ecology, evolution, and conservation: the Hawksbill sea turtle (Eretmochelys imbricata) and the Kemp’s Ridley sea turtle (Lepidochelys kempii). For the Hawksbill, a major rookery in the …


Bayesian Mediation Analyses For Zero-Inflated Data, Jinhong Cui Sep 2025

Bayesian Mediation Analyses For Zero-Inflated Data, Jinhong Cui

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Mediation analysis is a fundamental tool in causal inference, enabling researchers to disentangle the pathways through which an exposure affects an outcome via intermediate variables (mediators). It has been widely applied in social sciences, psychology, and healthcare-related studies. Traditionally, mediation analysis has been conducted within the linear structural equation modeling (LSEM) framework. However, recent advances have shifted attention toward the counterfactual framework due to its flexibility in defining causal effects and its capacity to accommodate non-linear relationships, parametric and non-parametric models. Building on this foundation, methodological developments in mediation analysis have expanded to address more complex data structures, such as …


Water Absorption, Surface Roughness And Flexural Strength Assessment Of Peek With And Without Aging., Pranjal Ramchandra Daundakr Sep 2025

Water Absorption, Surface Roughness And Flexural Strength Assessment Of Peek With And Without Aging., Pranjal Ramchandra Daundakr

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Polymethyl methacrylate (PMMA) has been the primary material for complete denture bases since its introduction in 1936 due to its esthetics, affordability, and ease of processing. However, PMMA demonstrates well-documented shortcomings, including relatively low flexural strength, high water absorption, and susceptibility to surface wear. These limitations lead to fractures, loss of occlusal vertical dimension (OVD), frequent relines, and compromised esthetics. Even advanced formats such as CAD-CAM milled and 3D printed PMMA remain prone to dimensional instability, microbial colonization, and long-term degradation. Polyetheretherketone (PEEK), a high-performance thermoplastic originally used in orthopedic and spinal implants, has recently been introduced into dentistry as …


In-Vitro Antimicrobial Activity, Demineralization Inhibition Potential, And Staining Effects Of Three Silver Fluoride Materials, Quiesly Torres Sep 2025

In-Vitro Antimicrobial Activity, Demineralization Inhibition Potential, And Staining Effects Of Three Silver Fluoride Materials, Quiesly Torres

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Background: Dental caries is a worldwide preventable public health problem. It affects any individuals regardless of their gender, age, ethnicity, and socioeconomic status. Silver diamine fluoride (SDF) has been extensively used for preventing cavities, but it has side effects; therefore, some other biocompatible antimicrobial and remineralization-inducing alternative materials have been developed. Purpose: This study aims to assess the in vitro antimicrobial activity, demineralization inhibition potential, and staining effect of SDF, Nano Silver Fluoride (NSF), and silver fluoride + potassium iodide (SF/KI). Methods: Three silver diamine fluoride-based materials were tested: SDF 38% (Advantage Arrest®, Elevate Oral Care, USA), 1500 ppm NSF …


Racial/Ethnic Heterogeneity In Women’S Aging Experiences Over Time: A Latent Transition Analysis, Joshua Christian Julian Lewis Sep 2025

Racial/Ethnic Heterogeneity In Women’S Aging Experiences Over Time: A Latent Transition Analysis, Joshua Christian Julian Lewis

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U.S. population aging and unprecedented racial/ethnic diversity will affect the types of social and healthcare services older adults need. These projections have renewed attention to healthy aging, which refers to the physiological/functional, psychological, and social capacity to maintain well-being. Extant research finds that most are aging unwell and through binary and biomedical operationalizations—which do not account for patterns of chronic conditions, disability, intersecting race / ethnic and gender inequality, socioculturally developed resources, and social relations—reifies the exceptions, typically men and non-Hispanic Whites, as the “aging well” benchmark. Integrating theoretical considerations of the life course, cumulative inequality, stress process, and limitations …


Voices From Two Secondary Newcomer Programs In Alabama: A Multiple Case Study, Carl Anthony Floyd Jr Sep 2025

Voices From Two Secondary Newcomer Programs In Alabama: A Multiple Case Study, Carl Anthony Floyd Jr

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This multiple case study investigates the design, implementation, and impact of two secondary newcomer programs in Alabama, with a focus on Students with Limited or Interrupted Formal Education (SLIFE) and non-SLIFE English Learner (EL) newcomers. Grounded in Esteban-Guitart et al.’s (2023) framework of community funds of knowledge and identity, the study explores how these programs function as community educational ecosystems. Data were collected through interviews, observations, and document reviews across two school districts and analyzed using ethnographic and thematic methods. Findings reveal that when newcomer programs are intentionally designed to leverage community assets and cultural identities, they provide meaningful academic, …


Parenting And Parental Well-Being As Risk And Resilience Factors For Mental Well-Being In Adolescents With And Without Neurodevelopmental Disorders, Wanqin Yu Sep 2025

Parenting And Parental Well-Being As Risk And Resilience Factors For Mental Well-Being In Adolescents With And Without Neurodevelopmental Disorders, Wanqin Yu

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Parenting practices and caregiver well-being are widely recognized as key determinants of adolescent mental health. However, few studies have examined how these factors operate in the context of neurodevelopmental disorders (NDDs), particularly through a risk and resilience framework. This study investigated how positive and negative parenting practices, caregiver well-being, and parenting stress relate to adolescents’ emotional well-being and internalizing problems. It also explored whether these variables differed between adolescents with and without NDDs. Participants included 105 adolescents aged 11–14 years (61.9% female; 52.4% diagnosed with an NDD) and their caregivers, drawn from a larger study on adolescent socio-emotional competencies. Caregivers …


Fqhc Turnaround Success – Does Leadership Matter?, Luis Orlando Amaro Sep 2025

Fqhc Turnaround Success – Does Leadership Matter?, Luis Orlando Amaro

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Background: Federally Qualified Health Centers (FQHCs) are essential providers of primary care in underserved communities but face growing risks of financial instability. Leader transitions, particularly at the executive level, may influence an organization's ability to recover from fiscal distress. This study examined whether executive succession—and the type of succession (internal vs. external)—was associated with financial turnaround among distressed FQHCs. Methods: Financial distress was assessed using the Modified Altman Z-Score, a validated indicator of fiscal health in nonprofit organizations. A longitudinal, quantitative design was used to analyze 850 FQHCs across the United States over a six-year period (2017–2022). Financial performance was …