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University of Alabama at Birmingham

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March 3, 2008 Reporter, University Of Alabama At Birmingham Mar 2008

March 3, 2008 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


February 18, 2008 Reporter, University Of Alabama At Birmingham Feb 2008

February 18, 2008 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


February 4, 2008 Reporter, University Of Alabama At Birmingham Feb 2008

February 4, 2008 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


Anthrax Cellular Entry Point Uncovered, Staff Jan 2008

Anthrax Cellular Entry Point Uncovered, Staff

Browse All News

No abstract provided.


January 21, 2008 Reporter, University Of Alabama At Birmingham Jan 2008

January 21, 2008 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


January 7, 2008 Reporter, University Of Alabama At Birmingham Jan 2008

January 7, 2008 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


Silver Bullet: Depleted Uranium As A Military Weapon, Ralph Patterson Jan 2008

Silver Bullet: Depleted Uranium As A Military Weapon, Ralph Patterson

Vulcan Historical Review

pp. 44-57


Uab Magazine - Spring 2008, University Of Alabama At Birmingham Jan 2008

Uab Magazine - Spring 2008, University Of Alabama At Birmingham

UAB Magazine

No abstract provided.


Inquiro 2 (Front Matter), Inquiro Staff Jan 2008

Inquiro 2 (Front Matter), Inquiro Staff

Inquiro (undergraduate research journal)

pp. -3


Inquiro 2 (Complete Issue), Inquiro Staff Jan 2008

Inquiro 2 (Complete Issue), Inquiro Staff

Inquiro (undergraduate research journal)

No abstract provided.


Nobel's Awarded, Inquiro Staff Jan 2008

Nobel's Awarded, Inquiro Staff

Inquiro (undergraduate research journal)

p. 4


Cloning Frozen Animals, Pratik Talati Jan 2008

Cloning Frozen Animals, Pratik Talati

Inquiro (undergraduate research journal)

pp. 5-6


Lessons From Sibs, Shweta Patel Jan 2008

Lessons From Sibs, Shweta Patel

Inquiro (undergraduate research journal)

pp. 14-15


Why Research?, Kim Trawick Jan 2008

Why Research?, Kim Trawick

Inquiro (undergraduate research journal)

pp. 10-11


Medicinal Benefits Of Green Tea?, Adam Threet, Natalie Mitchell Jan 2008

Medicinal Benefits Of Green Tea?, Adam Threet, Natalie Mitchell

Inquiro (undergraduate research journal)

pp. 12-13


Extracellular Atp Activates Multiple Calcium Signaling Pathways In Osteoblasts, Shweta Patel, Leah Strickland, Kaiyu Yuan, Min-Kyung Choo, Majd Zayzafoon Jan 2008

Extracellular Atp Activates Multiple Calcium Signaling Pathways In Osteoblasts, Shweta Patel, Leah Strickland, Kaiyu Yuan, Min-Kyung Choo, Majd Zayzafoon

Inquiro (undergraduate research journal)

pp. 37-41


Movement Patterns Of The Common Periwinkle Cenchritis Muricatus In The Rocky Supralittoral Zone Of San Salvador, Bahamas, Luke Stannard, Donna Howard Jan 2008

Movement Patterns Of The Common Periwinkle Cenchritis Muricatus In The Rocky Supralittoral Zone Of San Salvador, Bahamas, Luke Stannard, Donna Howard

Inquiro (undergraduate research journal)

pp. 42-45


The Importance Of Echinoderms: An Interview With Dr. Stephen Watts, Kim Trawick Jan 2008

The Importance Of Echinoderms: An Interview With Dr. Stephen Watts, Kim Trawick

Inquiro (undergraduate research journal)

pp. 23-25


Uab's 3 Goldwater Scholars, Inquiro Staff Jan 2008

Uab's 3 Goldwater Scholars, Inquiro Staff

Inquiro (undergraduate research journal)

p. 70


Cpg-Oligonucleotides Induce Tlr9 Mediated Cellular Invasion In A Sequence And Structure Dependent Manner, Sonja C. Brooks, Jason S. Hudson, Katri S. Selander, David E. Graves Jan 2008

Cpg-Oligonucleotides Induce Tlr9 Mediated Cellular Invasion In A Sequence And Structure Dependent Manner, Sonja C. Brooks, Jason S. Hudson, Katri S. Selander, David E. Graves

Inquiro (undergraduate research journal)

pp. 63-67


Correlation Between Hypertension And The Progression Of Alzheimer’S Disease, Sukhkamal Bhullar, Thomas Van Groen, Inga Kadish Jan 2008

Correlation Between Hypertension And The Progression Of Alzheimer’S Disease, Sukhkamal Bhullar, Thomas Van Groen, Inga Kadish

Inquiro (undergraduate research journal)

pp. 31-36


Inquiro 2 (End Matter), Inquiro Staff Jan 2008

Inquiro 2 (End Matter), Inquiro Staff

Inquiro (undergraduate research journal)

pp. 76-80


Collagen Mrna Expression In Human Fetal Lung Fibroblasts Treated With Varying Concentrations Of Ascorbic Acid, Pge2, And Tgf-Β1, Dixon Dorand Jan 2008

Collagen Mrna Expression In Human Fetal Lung Fibroblasts Treated With Varying Concentrations Of Ascorbic Acid, Pge2, And Tgf-Β1, Dixon Dorand

Inquiro (undergraduate research journal)

pp. 26-30


Analysis Of Hiv-1 Variable Loop 3-Specific Neutralizing Antibody Responses By Hiv-2/Hiv-1 Envelope Chimeras, Katie L. Davis Jan 2008

Analysis Of Hiv-1 Variable Loop 3-Specific Neutralizing Antibody Responses By Hiv-2/Hiv-1 Envelope Chimeras, Katie L. Davis

All ETDs from UAB

Defining the epitope specificities of the neutralizing antibody response to the HIV-1 envelope protein (Env) during natural human infection and in response to vaccination by HIV-1 immunogens could provide insight into the mechanisms of virus immune containment and facilitate vaccine design. Transplantation of discrete HIV-1 neutralizing epitopes into HIV-2 Env scaffolds may provide a sensitive, biologically functional context in which to quantify specific antibody reactivities in complex sera. Here we describe the development of a novel HIV-2 proviral scaffold (pHIV-2KR.X7) into which we have substituted the env V3 region of several laboratory and primary HIV-1 strains to yield a panel …


The Role Of Tgfß Signaling In Skeletal Development, Hwa-Seon Seo Jan 2008

The Role Of Tgfß Signaling In Skeletal Development, Hwa-Seon Seo

All ETDs from UAB

skeletal element is essential for body movement along with the joints, muscles, tendons and ligaments. They also protect internal organs and serve as a reservoir for hematopoietic stem cells and minerals. To accomplish these multiple tasks, the size and shape of the skeletal elements need to be carefully designed during development of the embryo. Skeletal formation in vertebrae is a complex developmental processes controlled by dynamic and well-balanced interactions between a number of molecular signals. Intensive efforts in the past several decades have made substantial progress in understanding molecular and cellular mechanisms of skeletal development. Despite the fact that TGFß …


Gender Difference In Traumatic Brain Injury Outcomes: Survival, Functional Independence, And Employment Status, Andrea T. Underhill Jan 2008

Gender Difference In Traumatic Brain Injury Outcomes: Survival, Functional Independence, And Employment Status, Andrea T. Underhill

All ETDs from UAB

Medical and rehabilitative care of women living with traumatic brain injury (TBI) is based on information drawn from research conducted primarily on men. Care for men may be adequate for women, but all of the body’s organs have the capability to respond differently based on gender, and research should examine the genders separately. This dissertation examines the survival to 24 months post-TBI and the functional independence and employment status at 12 and 24 months post-TBI of men and women. Participants were drawn from a longitudinal study of injured persons and include those diagnosed only with a TBI. Variables used in …


Feed Comparison For Dietary Standardization Of The Sea Urchin Lytechinus Variegatus And Assessment Of Parental Dietary Copper Toxicity By Fertilization And Embryological Tests, Heath W. Garris Jan 2008

Feed Comparison For Dietary Standardization Of The Sea Urchin Lytechinus Variegatus And Assessment Of Parental Dietary Copper Toxicity By Fertilization And Embryological Tests, Heath W. Garris

All ETDs from UAB

Toxicity tests monitoring the effects of anthropogenic substances on marine systems are considered an important part of environmental management. Sea urchin fertilization and embryological toxicity tests are successful in producing a graded response to toxicants, but standards for controlling the quality of parental urchins have not been developed. In Chapter 1, experimental populations of Lytechinus variegatus were fed either organic romaine lettuce and organic carrots, or a feed formulated for sea urchins for 13 weeks. Growth demographics were assessed and F1 progeny were compared for sensitivity to the toxicants copper sulfate, 1,3,5-trinitrobenzene, and sodium dodecyl sulfate by acute embryonic and …


Stochastic Energetics Of The Buttiker-Landauer Motor And Refrigerator, Ronald Benjamin Jan 2008

Stochastic Energetics Of The Buttiker-Landauer Motor And Refrigerator, Ronald Benjamin

All ETDs from UAB

We investigated the energetics of a Brownian motor driven by position dependent temperature, commonly known as the B¨uttiker-Landauer motor. Overdamped models (M = 0) predict that the motor can attain Carnot efficiency. However, the overdamped limit (M → 0), contradicts the previous prediction due to the kinetic energy contribution to the heat transfer. Using molecular dynamics simulation and numerical solution of the inertial Langevin equation, we confirmed that the motor can never achieve Carnot efficiency and verified that the heat flow via kinetic energy diverges asM−1/2 in the overdamped limit. The reciprocal process of the motor, namely the B¨uttiker-Landauer refrigerator …


Enzymatic And Proteomic Analysis Of Spinal Cord In A G93a Als Mouse Model, Page Jones Jan 2008

Enzymatic And Proteomic Analysis Of Spinal Cord In A G93a Als Mouse Model, Page Jones

All ETDs from UAB

Mutations to copper,zinc superoxide dismutase (Cu,Zn SOD or SOD1) are the only known causes of amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder characterized primarily by death of spinal motor neurons. While the molecular mechanisms responsible for motor neuron death in this disease remain to be elucidated, recent studies implicate mitochondrial dysfunction as a key factor in the pathogenesis of ALS. In support of this, we observed ALS-dependent alterations in key functions including creatine kinase activity and ATP levels, which could be linked to changes in the mitochondrial proteome. Importantly, extensive research efforts have failed to develop a treatment that significantly …


Calmodulin Binding To Cellular Flice Like Inhibitory Protein Modulates Fas-Induced Signaling And Tumorigenesis In Cholangiocarcinoma, Pritish Subhash Pawar Jan 2008

Calmodulin Binding To Cellular Flice Like Inhibitory Protein Modulates Fas-Induced Signaling And Tumorigenesis In Cholangiocarcinoma, Pritish Subhash Pawar

All ETDs from UAB

Cholangiocarcinoma, a fatal tumor arising from biliary epithelium, has very poor 5-year survival rate due to lack of early diagnosis and effective therapies. Induction of the Fas-mediated apoptosis is a promising therapeutic target in this tumor. Studies from our group and others have indicated that Fas-expression correlates inversely with disease progression and that CaM-antagonists induce apoptosis in cholangiocarcinoma cells in a Fas related manner. Further, we reported a direct and dynamic interaction of CaM and Fas and that CaM is recruited into the Fas-stimulated death inducing signaling complex (DISC), suggesting a cross talk between Fas and CaM pathways. The studies …