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Articles 3631 - 3660 of 6508
Full-Text Articles in Entire DC Network
The Role Of Ll-37 In Prostate Cancer And Its Potential As A Therapeutic Target, Jonathan Adam Hensel
The Role Of Ll-37 In Prostate Cancer And Its Potential As A Therapeutic Target, Jonathan Adam Hensel
All ETDs from UAB
LL-37 is the only cathelicidin-derived anti-microbial peptide in humans and has been shown to stimulate proliferation, angiogenesis, cellular migration and inhibit apoptosis, in addition to serving as a chemoattractant for leukocytes. It is produced primarily by epithelial cells and leukocytes, and has recently been discovered to be over-expressed in breast, ovarian and lung cancers. Based on these findings, we compared levels of LL-37 expression in benign and cancerous human prostate tissues. Results of this investigation demonstrated that LL-37 is increasingly over-expressed in primary prostate tumors in a grade dependent manner and in metastatic lesions. Since the physiological mechanisms of LL-37 …
Protein Modifications And The Response To Oxidized Lipids In Cardiovascular Cells, Ashlee Higdon
Protein Modifications And The Response To Oxidized Lipids In Cardiovascular Cells, Ashlee Higdon
All ETDs from UAB
Free radical catalyzed oxidation of polyunsaturated fatty acids (PUFAs) such as arachidonic acid is increased in cardiovascular disease states, including atherosclerosis and heart failure. Oxidized lipids have been extensively studied and found to recapitulate several key steps in atherogenesis. However, clinical trials with antioxidants such as alpha-tocopherol have been less promising than originally predicted. Now appreciated as more than just biomarkers of disease, lipid peroxidation products have been shown to have roles in pathogenesis as well as physiology. Of particular interest are reactive lipid species that possess electrophilic carbonyls enabling them to act in a receptor-independent manner. To date, the …
Pax5 Controls B Lineage Specific Gene Expression Program Through Association With The Nuclear Matrix, Sang Yong Hong
Pax5 Controls B Lineage Specific Gene Expression Program Through Association With The Nuclear Matrix, Sang Yong Hong
All ETDs from UAB
Pax5 is an essential regulator for B lineage cell development and controls hundreds of positive and negative target genes. The nuclear matrix (NM) has long been proposed to provide a dynamic structural support for biological reactions inside of the nucleus, including DNA replication, RNA transcription, and RNA splicing. Although Pax5 binding sites have been identified in numerous Pax5 target genes, it is not clear how Pax5 controls so many target genes. In this dissertation, I demonstrate that Pax5 association with the NM is essential for regulation of the B lineage specific gene expression program. In part I, I found that …
Efficacy Of Sterisil In The Treatment Of Dental Unit Waterlines, Don Schmidtke
Efficacy Of Sterisil In The Treatment Of Dental Unit Waterlines, Don Schmidtke
All ETDs from UAB
Introduction: Dental unit waterlines (DUWL) are an ideal home for bacterial microorganisms to grow, multiply, and develop complex living colonies commonly known as "biofilm." The American Dental Association (ADA) and the Centers for Disease Control and Prevention (CDC) have recommendations to maintain DUWL heterotrophic plate count bacteria levels below 500 colony forming units per milliliter (CFU/ml) of water. The aim of this study is to determine whether Sterisil PureTube is able to control the bacterial load in the orthodontic clinic to recommended levels. Methods: Waterline samples from the twelve dental chairs in the orthodontic clinic were used in this study. …
The Role Of Cd19 In Follicular Dendritic Cell Activation, Riley Croom Myers
The Role Of Cd19 In Follicular Dendritic Cell Activation, Riley Croom Myers
All ETDs from UAB
Germinal Centers (GC) are organized foci in secondary lymphoid organs of birds and mammals and are the principle sites of memory B cell generation and plasma cell formation. GC concentrate antigen within follicles to facilitate recognition by responding B cells to promote somatic hypermutation and affinity maturation. Follicular dendritic cells (FDC) reside within the light zones of GC and serve to facilitate B cell interactions with antigen, as well as B cell selection, proliferation, and survival. The work contained within this dissertation addresses the collaborative interactions between B cells and FDC. FDC within an active, GC-containing follicle express an array …
Cognitive Impact Of Pediatric Multiple Sclerosis Varies By Race, Jim Bakken
Cognitive Impact Of Pediatric Multiple Sclerosis Varies By Race, Jim Bakken
Browse All News
No abstract provided.
Conference Focuses On The 'Other' Brain Cells, Staff
Conference Focuses On The 'Other' Brain Cells, Staff
Browse All News
No abstract provided.
Professor Edits New Genetics Handbook, Jim Bakken
Professor Edits New Genetics Handbook, Jim Bakken
Browse All News
No abstract provided.
November 22, 2010 Reporter, University Of Alabama At Birmingham
November 22, 2010 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
Two University Honors Program Students Accepted Into Teach For America Program, Jim Bakken
Two University Honors Program Students Accepted Into Teach For America Program, Jim Bakken
Browse All News
No abstract provided.
Uab Students Bring Phun To Area Elementary School, Jim Bakken
Uab Students Bring Phun To Area Elementary School, Jim Bakken
Browse All News
No abstract provided.
Woods Couchman Appointed Professor Emerita, Alicia Rohan
Woods Couchman Appointed Professor Emerita, Alicia Rohan
Browse All News
No abstract provided.
Shalev Appointed To The Nancy R. And Eugene C. Gwaltney Family Endowed Chair In Juvenile Diabetes Research, Jim Bakken
Shalev Appointed To The Nancy R. And Eugene C. Gwaltney Family Endowed Chair In Juvenile Diabetes Research, Jim Bakken
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No abstract provided.
Daniel Pierce Of Raleigh, N.C., And Nishita Baxi Of Cordova, Tenn., Named Mr. And Ms. Uab 2010, Shannon Thomason
Daniel Pierce Of Raleigh, N.C., And Nishita Baxi Of Cordova, Tenn., Named Mr. And Ms. Uab 2010, Shannon Thomason
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No abstract provided.
November 8, 2010 Reporter, University Of Alabama At Birmingham
November 8, 2010 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
October 18, 2010 Reporter, University Of Alabama At Birmingham
October 18, 2010 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
Uab Physiology And Biophysics Chair Dale Benos Dead At Age 60, Staff
Uab Physiology And Biophysics Chair Dale Benos Dead At Age 60, Staff
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No abstract provided.
Nsf Grant Extends Uab Research In Antarctica, Jim Bakken
Nsf Grant Extends Uab Research In Antarctica, Jim Bakken
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No abstract provided.
Directions - Fall 2010, Mervyn H. Sterne Library
Directions - Fall 2010, Mervyn H. Sterne Library
Directions (Sterne Library, 1985-2015)
No abstract provided.
$11.5 Million Grant Arms Uab Comprehensive Cancer Center Fight Against Pancreatic Cancer, Jim Bakken
$11.5 Million Grant Arms Uab Comprehensive Cancer Center Fight Against Pancreatic Cancer, Jim Bakken
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No abstract provided.
Uab College Of Arts And Sciences Announces Scholarships, Shannon Thomason
Uab College Of Arts And Sciences Announces Scholarships, Shannon Thomason
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No abstract provided.
Uab College Of Arts And Sciences Announces Scholarships, Staff
Uab College Of Arts And Sciences Announces Scholarships, Staff
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No abstract provided.
September 6, 2010 Reporter, University Of Alabama At Birmingham
September 6, 2010 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
Uab Researchers Develop New Test For Shellfish Bacteria, Jim Bakken
Uab Researchers Develop New Test For Shellfish Bacteria, Jim Bakken
Browse All News
No abstract provided.
August 25, 2010 Greenmail, University Of Alabama At Birmingham
August 25, 2010 Greenmail, University Of Alabama At Birmingham
GreenMail (student newsletter through 2024)
No abstract provided.
Uab Cord Teaches Kids The Realities Of Scientific Research, Jim Bakken
Uab Cord Teaches Kids The Realities Of Scientific Research, Jim Bakken
Browse All News
No abstract provided.
August 23, 2010 Reporter, University Of Alabama At Birmingham
August 23, 2010 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
August 9, 2010 Reporter, University Of Alabama At Birmingham
August 9, 2010 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
2010 Uab Summer Research Expo, University Of Alabama At Birmingham
2010 Uab Summer Research Expo, University Of Alabama At Birmingham
Expo Programs
Catalog of undergrauate student research poster presentations with abstracts.
July 21, 2010 Greenmail, University Of Alabama At Birmingham
July 21, 2010 Greenmail, University Of Alabama At Birmingham
GreenMail (student newsletter through 2024)
No abstract provided.