Digital Commons Network^™

Phosphogypsum-Based Road Materials: A Review Of Practicality, Longevity, And Safety In The United States, Catesby Elisabeth Mallard

ETDs from 2020-2029

The development of the phosphate fertilizer industry, while integral to the success of modern-day agriculture, continues to produce staggering amounts of phosphogypsum (PG), an acidic and hazardous waste byproduct concentrated with heavy metals, technologically enhanced naturally occurring materials (TENORM), and other toxic elements. Due to the potentially harmful emission of radon from PG, the United States (US) Environmental Protection Agency (EPA) has regulated the disposal of PG in engineered stacks under the National Emission Standards for Hazardous Air Pollutants (NESHAP) for nearly four decades. However, with roughly five tons of PG produced per single ton of phosphoric acid, and a …

Dock7 Is A Novel Modifier Of Duchenne Muscular Dystrophy Pathology, Katherine English

ETDs from 2020-2029

Duchenne muscular dystrophy (DMD) is a progressive, x-linked neuromuscular disorder affecting 1/5000 male births every year. DMD results from mutations in DMD, a critical structural protein within the muscle. In the absence of Dystrophin, the muscle degrades, increasing inflammation, destabilizing the cell membrane and going through constant cycles of regeneration which depletes the stem cell population. Over time, muscle tissue is replaced by fibrosis and adipose tissue, leading to loss of ambulation, respiratory and cardiac failure leading to death by early 20s. The standard of care for DMD patients is corticosteroid treatment. However, gene therapies have recently emerged which present …

Finite Element Analysis Of Post Vs Threaded-Post Glenoid Baseplates In Reverse Total Shoulder Arthroplasty: A Comparative Study, Christopher Morgan

ETDs from 2020-2029

This study compared a standard‑post baseplate with a threaded‑post baseplate in reverse total shoulder arthroplasty (rTSA) to determine whether threaded central fixation improves micromotion and stress distribution. A finite element model of a left scapula with a commercially available rTSA system was created; the two designs differed only by the central post (standard press‑fit versus threaded). A 756 N physiological load was applied at 60°, 90°, and 120° of abduction. Outcomes included total and directional relative micromotion at the bone–implant interface and von Mises stress in the glenoid and baseplate. Total micromotion remained below the 150 µm osseointegration threshold for …

The Healthcare Transition Experiences Of Emerging Adults With Congenital Adrenal Hyperplasia, Leslie Noojin Pitts

ETDs from 2020-2029

Congenital adrenal hyperplasia (CAH) is a group of disorders characterized by enzyme deficiencies impairing adrenal hormone production and requiring lifelong management. Individuals with CAH experience increased morbidity and mortality due to the underlying condition, steroid exposure, and inadequate preventative care. Despite clinical guidelines recommending a structured healthcare transition (HCT), little is known about the HCT experiences of emerging adults with CAH. Understanding these experiences is critical for identifying practice gaps and developing interventions to improve health outcomes. This qualitative descriptive study explored the HCT experiences, challenges, and outcomes of emerging adults with CAH, as guided by the refined Social Ecological …

Investigating The Effects Of Increased O-Glcnaylation On Pathology In Alzheimer’S Disease, Melissa Louise Garcia

ETDs from 2020-2029

Alzheimer’s disease (AD) is currently the 7th leading cause of death, with few treatment options. It is known that AD pathology begins 20-30 years before clinical symptoms manifest. Some of the earliest pathological changes occur in glial cells of the hippocampus, causing them to become chronically reactive, as well as the accumulation of Amyloid-β (Aβ) in the hippocampus and hyperphosphorylated Tau (pTau) in the locus coeruleus, resulting in dysfunction of the noradrenergic (NA) system. Preclinical studies have shown promise in the abilities of the post-translational modification O-linked β-N-acetylglucosamine (O-GlcNAc). O-GlcNAc is a tightly regulated reversible enzymatic modification controlled by the …

Elucidating The Role Of The Rnf20 Histone Modifier In Pancreatic Beta Cells, Tanya Hans Pierre

ETDs from 2020-2029

Diabetes is defined as a loss of functional beta cell mass. It is classically categorized into Type 1 Diabetes (T1D), immune-mediated beta cell destruction and Type 2 Diabetes, which is characterized by whole body insulin resistance alongside beta cell dysregulation. The incidence of diabetes worldwide has risen annually. Despite the presence of therapeutic interventions, diabetes’ heterogeneity can prompt ineffective glycemic control and the development of diabetes-associated comorbidities. For that reason, new approaches to glycemic control for individuals with diabetes are required. One approach to restore glucose homeostasis is beta cell replacement therapy, in which stem cells are programmed into beta-like …

The Association Of Motherhood And Maternal-Related Life Events And Cardiovascular-Related Health, Disease Events, And Mortality, Taishayla Mckitt

ETDs from 2020-2029

More than 40% of U.S. women have cardiovascular disease (CVD), and nearly half have at least one major risk factor. Sparse evidence exists related to the role of childrearing (regardless of prior pregnancy) on CVD. A recent literature review highlighted the influence of reproduction on CVD and health and identified opportunities for advancement. At present, it has yet to be discovered from prospective epidemiologic studies the extent to which parenting and maternal events have influence on cardiovascular health and clinical events. It has been demonstrated that parous women have greater prevalence of cardiovascular risk factors (e.g., short sleep duration and …

Balancing Act: How Graduate Student Mothers Navigate Dual Roles, Jessica Seymour

ETDs from 2020-2029

Graduate student mothers represent a growing but often overlooked population within higher education. While research has examined the experiences of undergraduate student parents, significantly less attention has been given to graduate students who balance academic responsibilities with motherhood. This study explores the experiences of graduate student mothers enrolled at public four-year institutions, focusing on the institutional, financial, and social barriers that shape their academic success and participation in campus life. Using a phenomenological approach, this research seeks to understand how graduate student mothers navigate the dual roles of parenting and pursuing advanced degrees. The study employs a Borderland Theoretical Framework …

Comparative Evaluation Of Translucency, Fluorescence, And Structural Analysis Of 3d-Printed Vs. Conventionally Fabricated 3y, 4y And 5y Zirconia, Surabhi Chhabra

ETDs from 2020-2029

Statement of Problem: Additive manufacturing has emerged as an alternative to conventional milling for zirconia-based dental restorations because of its potential to reduce material waste and increase design flexibility. However, whether 3D-printed zirconia can provide optical and structural properties comparable with those of conventionally milled zirconia for esthetic applications remains unclear. Purpose: The purpose of this in vitro study was to compare the optical properties of 3D-printed zirconia and conventionally milled 3Y, 4Y, and 5Y zirconia, as measured by translucency and fluorescence, and to evaluate their structural characteristics, as measured by density, porosity, phase composition, and surface morphology. Materials and …

Recognizing Patients In Places: A Multilevel Analysis Of Severe Heat-Related Illness Risk In Birmingham, Al, Andria Cimino

ETDs from 2020-2029

Socially marginalized people face a higher risk of adverse health outcomes from extreme heat—as many as 12,000 U.S. deaths a year are attributable to heat-related illness (HRI), a preventable but multifactorial condition. Where one lives plays a critical role in HRI incidence, with evidence linking historically segregated and disinvested urban environments to a higher risk. The literature also suggests that Black adults experience worse HRI outcomes than non-Hispanic White adults, and that men are often, though not always, at higher risk than women. Individuals with heat-sensitive conditions and socially isolated adults also face elevated risk. Yet the mechanisms by which …

Protein Glycosylation In Natural And Synthetic Minimal Genome Mycoplasmas, John Sanford

ETDs from 2020-2029

Mycoplasmas are cell wall-less bacterial symbionts with remarkably streamlined genomes. Mycoplasmas offer two intriguing model organisms for studying concepts of minimal life. Mycoplasma genitalium has streamlined its genome to 580-kbp while maintaining virulence to suit its niche of parasitizing the human urogenital tract. The J. Craig Venter Institute has synthesized and transplanted a 543-kbp genome into a recipient cell, resulting in a non-pathogenic organism termed JCVI-syn3A. The conservation of a biological process in M. genitalium and JCVI-syn3A strongly implies an essential function in mycoplasmas, and potentially all life. Despite common thought of mycoplasmas being the simplest cells, much of their …

May 5, 2026 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

April 24, 2026 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

April 22, 2026 Blazer Weekly, University Of Alabama At Birmingham

Blazer Weekly (student newsletter)

No abstract provided.

Burnout Sentinel: An Early Warning System For Student Burnout Using Workload And Recovery Indicators, Minh Duy Do

Expo Student Presentations

2026 Spring Expo Video Essay Presentation

• Biological & Life Sciences
• Health Sciences & Health Professions
• Physical & Applied Sciences
• Service-Learning
• Social & Behavioral Sciences

Effect Of Missense Mutation In Pah Gene At Position 46: Glycine To Arginine, Lily Hammond, Tiffany Tran

Expo Student Presentations

2026 Spring Expo Online Poster Presentation

• Biological & Life Sciences

Hif1Α-Driven Glycolysis Controls Ifn-Γ Production And Immune Checkpoint Blockade Response In Hypoxic T Cells, Zach Lewis, Hongxing Shen, Oluwagbemiga A. Ojo, Vivian Y. Shi, Haitao Ding, Abdelrahman Yassin, James A. Bonner, Lewis Zhichang Shi

Expo Student Presentations

2026 Spring Expo Poster Presentation

• Biological & Life Sciences

Sex Specific Effects Of Early Life Stress On Blood Pressure Regulation Is Independent Of Arterial Stiffness In Rats, Vanvy Ly, Hiruni M. Aponso, David M. Pollack

Expo Student Presentations

2026 Spring Expo Poster Presentation

• Biological & Life Sciences

Investigating The Missense Mutation In Men1 At Amino Acid Position 331 Changing Asparagine To Isoleucine, Anika Prasad

Expo Student Presentations

2026 Spring Expo Online Poster Presentation

• Biological & Life Sciences

The Effects Of Cannabis Use On Physical Activity, Nitya Chiru, Brionna L. Smith, Karen L. Cropsey, Elizabeth K. Lee

Expo Student Presentations

2026 Spring Expo Poster Presentation

• Biological & Life Sciences

Uab Libraries News, 03 2026, Uab Libraries

UAB Libraries News

No abstract provided.

February 13, 2026 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

February 11, 2026 Blazer Weekly, University Of Alabama At Birmingham

Blazer Weekly (student newsletter)

No abstract provided.

Role Of Depression And Anxiety On Brain Care Scores In A Primary Care Setting: A Preliminary Analysis Of The Bham Registry, Terina Lane Myers

ETDs from 2020-2029

While the field of brain aging research continues to grow at a rapid pace, there is still much to learn about how certain factors influence brain aging as well as when and how these factors can be intervened upon. Cerebrovascular and neurodegenerative diseases continue to pose a major obstacle to healthy brain aging and the better we understand the risk factors of these diseases, the greater chance we have at mitigation strategies and prevention. Previous research has identified key factors, consisting of physical, lifestyle, and socio-emotional aspects of life, which have the greatest impact on brain aging. These factors overlap …

Cellular Therapy For The Treatment Of Ischemic Limb Disease, Akazha Nicole Green

ETDs from 2020-2029

Ischemic limb disease continues to pose major clinical challenges. The effect of this disease causes restricted blood flow, which is followed by a limited ability to regenerate in the vascular tissues. The purpose of this study is to address the current limitations in producing large-scale generation of Smooth Muscle Cells (SMCs) derived from human induced pluripotent stem cells (hiPSCs) and then assessing their potential therapeutic efficiency individually and in combination with endothelial cells (ECs) for vascular repair. A dynamic three-dimensional (3D) culture system was integrated with a two- dimensional (2D) expansion to enhance cell culture yield while maintaining contractile marker …

Unpacking A Health Paradox Among Preterm Infants: Insights From A Providers' Perception, Brittany Nicole Stewart

ETDs from 2020-2029

The goal of this dissertation is to examine the varying perspectives, or frames, of providers regarding decision-making in the NICU, which includes how they view neonates and their families, their roles as providers, and the way their frames possibly impact the care they give to the infants. In this dissertation, I conduct in-depth interviews with 34 NICU providers and professionals that provide their services in the NICU, including doctors, nurse practitioners, nurses, various therapists (i.e. respiratory, physical, occupational), and two other providers from two other professions. Within the NICU, a common stereotype exists that is a belief that White boy …

Conserved Chromatin Programs Orchestrate Cardiac Cell States In Health And Disease And Drive Cardiomyocyte Proliferation After Injury, Xiaoxiao Geng

ETDs from 2020-2029

Chromatin structure is a central regulator of gene expression and cellular identity, yet the chromatin structural factors driving cardiac disease and regeneration remain incompletely defined. This dissertation investigates how modulation of chromatin architecture shapes pathological and regenerative cardiac phenotypes through integrated single-cell transcriptomic, epigenomic, and functional analyses. To determine whether chromatin structural regulators distinguish healthy from diseased cardiac states, we curated a comprehensive list of chromatin structural genes and applied it to single-nuclei RNA sequencing datasets from human hearts with and without dilated cardiomyopathy (DCM). Chromatin structural gene expression effectively stratified cardiomyocyte and fibroblast populations by disease status. Diseased cardiomyocytes …

Novel Retinal Biomarker Development In Early Alzheimer’S Disease, Swetha Ravichandran

ETDs from 2020-2029

Alzheimer’s disease is a progressive neurodegenerative disorder that causes damage to the neurons that are present in the brain. Progress in the management and treatment of AD is limited by lack of early diagnostics, which are critical to the development of effective therapies. It is therefore critical to develop non-invasive/cost efficient biomarkers to aid in early diagnosis and interventions to prevent or delay dementia onset. While Positron Emission Tomography (PET) and cerebrospinal fluid assessment have greatest utility, they are not routinely used because they are expensive and invasive, respectively. Retinal imaging offers a promising, low-cost, and non-invasive avenue for detecting …

Early Life Stress Mediates Cardiovascular Disease Risk Through Csf1r And Increases Risk Of Lupus Through Mature B-Cells, Cailin Elizabeth Kellum

ETDs from 2020-2029

The term Early Life Stress (ELS) encompasses traumatic events occurring before the age of 18 such as physical abuse, verbal abuse, household dysfunctions, sexual abuse, childhood neglect, child maltreatment, and adverse childhood experiences. The traumatic psychological and physical experiences in early life are widely known to cause enduring effects on mental and physical health in adulthood. Of note, individuals with ELS have adverse health outcomes earlier in adulthood and with more severity such as in the case of Systemic Lupus Erythematous (SLE), an autoimmune disease. The risk for autoimmunity and cardiovascular disease (CVD) increases with ELS exposure and CVD is …

Awareness And Knowledge Of Juvenile Idiopathic Arthritis Among Orthodontic And Oral And Maxillofacial Surgery Specialties In The United States., Kavita Nayar

ETDs from 2020-2029

Introduction: Juvenile Idiopathic Arthritis (JIA) is the most common chronic pediatric arthritis, frequently involving the temporomandibular joint (TMJ) and resulting in facial growth disturbances, functional impairment, and complex multidisciplinary treatment needs. Despite its clinical relevance, limited awareness and inconsistent management strategies exist among specialists who are involved in the care of these patients including orthodontists, oral and maxillofacial surgeons and rheumatologists. This study aimed to evaluate the understanding, knowledge and interdisciplinary management practices between board-certified orthodontists and oral and maxillofacial surgeons (OMSs) across the United States regarding JIA. Materials and Methods: A cross-sectional survey was distributed electronically via Qualtrics to …