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Articles 2611 - 2640 of 6508
Full-Text Articles in Entire DC Network
Bcla As An Adjunct To Current Bacillus Anthracis Vaccination And Therapy Protocols, Juan Bosco Rodriguez Barrantes
Bcla As An Adjunct To Current Bacillus Anthracis Vaccination And Therapy Protocols, Juan Bosco Rodriguez Barrantes
All ETDs from UAB
Bacillus anthracis (Ba) is a Gram,-positive zoonotic bacterium that causes inhala- tional, cutaneous and intestinal Anthrax Disease. Although the infectious form of Ba is its endospore (spore), only the tripartite toxin-producing vegetative bacteria causes disease pathology. While current vaccination strategies target the Protective Antigen (PA) com- ponent of this toxin, vaccine-elicited immunity to the spore form of Ba is lacking. How- ever, vaccines targeting spore components of Ba have the potential to neutralize the in- fectious form of Ba. We sought to determine if antibodies elicited through immunization with the main antigenic component of the spore surface- Bacillus collagen-like protein …
Investigating The Role Of Myristoylated Alanine Rich C Kinase Substrate's (Marcks's) Effector Domain In Lung And Brain Cancer Biology, Timothy D. Rohrbach
Investigating The Role Of Myristoylated Alanine Rich C Kinase Substrate's (Marcks's) Effector Domain In Lung And Brain Cancer Biology, Timothy D. Rohrbach
All ETDs from UAB
In this study, we investigated the role MARCKS's Effector Domain plays in lung and brain cancer biology. Initially, we identified that MARCKS was present in a range of lung cancer histologies including: squamous cell, adenocarcinoma, and normal lung tissues among others. In addition, lung adenocarcinoma patients with a mutation in the MARCKS gene correlated with decreased survival as determined by The Cancer Genome Atlas. In vitro studies identified that the phosphorylation status of MARCKS's Effector Domain was able to influence lung cancer radiation sensitivity. When MARCKS's Effector Domain was in a non-phosphorylated state, A549 lung cancer cell lines experienced increased …
Responses Of Marine Benthic Invertebrates Of The Western Antarctic Peninsula To Ocean Acidification And Elevated Temperature, Julie Schram
Responses Of Marine Benthic Invertebrates Of The Western Antarctic Peninsula To Ocean Acidification And Elevated Temperature, Julie Schram
All ETDs from UAB
Increases in atmospheric carbon dioxide (CO2) concentrations are continuing to increase and have been linked with decreasing seawater pH as well as atmospheric and seawater warming. Warming along the western Antarctic Peninsula is occurring at one of the fastest rates recorded to date and triggering further environmental changes. To date there are few records of the current seawater pH and temperature conditions experienced by benthic organisms in this region or how they will respond to shifts in pH and temperature predicted to occur by 2100 or sooner. The primary aim of this dissertation was to pa-rameterize the current seawater carbonate …
Role Of Vapb/Als8 Signaling Through Lar Receptor, Jessica Lindsey Winek Schultz
Role Of Vapb/Als8 Signaling Through Lar Receptor, Jessica Lindsey Winek Schultz
All ETDs from UAB
In humans, a P56S point mutation in the VAPB/ALS8 MSP domain is associated with amyotrophic lateral sclerosis (ALS) and late-onset spinal muscular atrophy (SMA). The N-terminal MSP domain is cleaved from the C-terminus, and secreted through an unknown, nonconventional manner. The P56S mutation inhibits secretion of the MSP domain. We use Caenorhabditis elegans to study live secretion of VPR-1, as well as to understand vMSP receptor signaling in muscle and gonad. To study the secretion mechanism of VPR-1 we created a transgenic line of C. elegans with a fluorescently tagged VPR-1. Using this model, we were able to visualize live …
A Randomized Trial Evaluating Child Dog-Bite Prevention In Rural China Through Video-Based Testimonials, Jiabin Shen
A Randomized Trial Evaluating Child Dog-Bite Prevention In Rural China Through Video-Based Testimonials, Jiabin Shen
All ETDs from UAB
Dog-bite injuries pose a significant threat to children around the world. School-aged children are especially at risk of injuries because of their cognitively immature tendency toward poor perception of vulnerability regarding risky behaviors. This risk is elevated further for millions of school-aged children living in rural China due to the large number of stray dogs, all potential rabies carriers. Effective intervention programs for pediatric dog-bite injuries are sparse. Most existing programs were based on public health concerns and only involve the impartment of safety knowledge to children. They produced mixed results in changing actual behaviors with dogs. Based on the …
The Effects Of 6 Weeks Of High Intensity Interval Training Vs. Moderate Intensity Training On Changes In Body Composition, Corey Noles
All ETDs from UAB
THE EFFECTS OF 6 WEEKS OF HIGH INTENSITY INTERVAL TRAINING VS. MODERATE INTENSITY TRAINING ON CHANGES IN BODY COMPOSITION COREY NOLES KINESIOLOGY ABSTRACT Background: It is important to identify strategies to promote exercise adherence and to identify an optimal exercise stimulus to prevent adverse health outcomes associated with obesity. Low-volume high-intensity interval training (HIIT) has recently been shown to improve a number of cardiometabolic health outcomes similarly to moderate intensity exercise training (MIT) despite requiring 1 hr of training per week for HIIT vs 6 hrs for ET. However, less is known about HIIT and its effects on body composition. …
Uab Looks To Build On Many 2014 Successes In The New Year, Jim Bakken
Uab Looks To Build On Many 2014 Successes In The New Year, Jim Bakken
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No abstract provided.
Uab Enrolls Nation's First Patient In Phase Iii Drug Trial For Preeclampsia, Tyler Greer
Uab Enrolls Nation's First Patient In Phase Iii Drug Trial For Preeclampsia, Tyler Greer
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No abstract provided.
New Study Of Proteins In Space Could Yield Better Understanding, New Drug Development, In Addition To Future Scientists, Jim Bakken
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No abstract provided.
No Extra Risk With Zoster Vax In Ra Patients On Biologics, Staff
No Extra Risk With Zoster Vax In Ra Patients On Biologics, Staff
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No abstract provided.
Novel Theory Connects Mothers To Childhood Obesity: Evolution Is The Cause, Moms Are The Cure, Jim Bakken
Novel Theory Connects Mothers To Childhood Obesity: Evolution Is The Cause, Moms Are The Cure, Jim Bakken
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No abstract provided.
Barghi, Ryder In The Running For International Academic Honors, Staff
Barghi, Ryder In The Running For International Academic Honors, Staff
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No abstract provided.
Uab Cancer Center And Asu Receive Grant To Address Cancer Health Disparities, Beena Thannickal
Uab Cancer Center And Asu Receive Grant To Address Cancer Health Disparities, Beena Thannickal
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No abstract provided.
Uab Cancer Center And Asu Receive Grant To Address Cancer Health Disparities, Staff
Uab Cancer Center And Asu Receive Grant To Address Cancer Health Disparities, Staff
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No abstract provided.
Benveniste Named Interim Senior Associate Dean For Research Administration & Development, Kendra Carter
Benveniste Named Interim Senior Associate Dean For Research Administration & Development, Kendra Carter
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No abstract provided.
In Human Clinical Trial, Uab To Test Drug Shown To Completely Reverse Diabetes In Human Islets, Mice, Tyler Greer
In Human Clinical Trial, Uab To Test Drug Shown To Completely Reverse Diabetes In Human Islets, Mice, Tyler Greer
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No abstract provided.
Gillespie Named To The Pediatric Brain Tumor Foundation's Research Advisory Network, Staff
Gillespie Named To The Pediatric Brain Tumor Foundation's Research Advisory Network, Staff
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No abstract provided.
Bland Named Distinguished Faculty Lecturer, Traci Bratton
Bland Named Distinguished Faculty Lecturer, Traci Bratton
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No abstract provided.
Uab Launches Roadmap For Underrepresented Grad Students Interested In Neuroscience, Alicia Rohan
Uab Launches Roadmap For Underrepresented Grad Students Interested In Neuroscience, Alicia Rohan
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No abstract provided.
Nasa Research Helps Map Protein Structures - Key In The Development Of New Disease-Fighting Drugs, Staff
Nasa Research Helps Map Protein Structures - Key In The Development Of New Disease-Fighting Drugs, Staff
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No abstract provided.
Southern 'Stroke Belt' Study Initiates Nationwide Study, Staff
Southern 'Stroke Belt' Study Initiates Nationwide Study, Staff
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No abstract provided.
Mitochondria Expert Invited To Nih Strategic Workshop, Jeff Hansen
Mitochondria Expert Invited To Nih Strategic Workshop, Jeff Hansen
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No abstract provided.
Uab Prayer Flags To Welcome Dalai Lama In Outdoor Aeiva Installation Oct. 20-26, Shannon Thomason
Uab Prayer Flags To Welcome Dalai Lama In Outdoor Aeiva Installation Oct. 20-26, Shannon Thomason
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No abstract provided.
Mr. And Ms. Uab Finalists Announced, Staff
National Alumni Society Honors Five At Leadership Awards, Shannon Thomason
National Alumni Society Honors Five At Leadership Awards, Shannon Thomason
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No abstract provided.
Ali To Coordinate Undergraduate Research Office, Traci Bratton
Ali To Coordinate Undergraduate Research Office, Traci Bratton
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No abstract provided.
Seven New Members Appointed To The Montgomery Regional Medical Campus Advisory Board, Staff
Seven New Members Appointed To The Montgomery Regional Medical Campus Advisory Board, Staff
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No abstract provided.
Offering Promise Instead Of Health Challenges To Cancer Survivors, Beena Thannickal
Offering Promise Instead Of Health Challenges To Cancer Survivors, Beena Thannickal
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No abstract provided.
Uab Mitochondria Expert Invited To Nih Strategic Workshop, Traci Bratton
Uab Mitochondria Expert Invited To Nih Strategic Workshop, Traci Bratton
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No abstract provided.
Dentistry's Mathews Named 2013-14 Employee Of The Year, Natalie Wade
Dentistry's Mathews Named 2013-14 Employee Of The Year, Natalie Wade
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No abstract provided.