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Uab Team Wants To Build A Roadmap To A Model City, Matt Windsor

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The Best And Worst Things You Can Do For Your Heart, Staff

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Weight Cycling Does Not Adversely Affect Cardiovascular Outcomes In Women With Suspected Myocardial Ischemia, Adam Pope

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Baskin Selected As President Of The Jefferson County Health Action Partnership, Staff

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Recruitment Begins For New Study Examining Diet As Treatment For Type 2 Diabetes Patients, Staff

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$3.25 Million R01 Grant Will Explore The Long-Term Impact Of Diet, Exercise On Symptoms Of Adults With Hiv, Staff

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Does A Smart Fitness Device Or App Help You Lose Weight?, Alicia Rohan

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Uab Magazine - Summer 2019, University Of Alabama At Birmingham

UAB Magazine

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Dental Dimensions In Non-Syndromic Patients With Unilateral Cleft Palate, Blake Boleware

All ETDs from UAB

Objective: The main objective of this study is to determine if any difference in tooth size exists between the maxillary quadrants in non-syndromic patients with unilateral cleft palate using cone beam computed tomography. By understanding the effects of cleft palate on tooth morphology, the multidisciplinary team of specialists involved with the care and treatment of a patient with cleft lip/palate can better understand the intricacies of necessary therapy. This understanding can, in turn, be used for proper planning of desired treatments which can increase the chance of successful achievement of desired outcomes. Materials and Methods: CBCT volumes for 18 patients …

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Assessing Diabetes Risk Among Hispanic Populations: Development And Validation Of A Risk Score Using Readily Available Information, Lucia Juarez

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Background: Diabetes prevalence is increasing worldwide affecting vulnerable popula-tions, in particular Hispanics living in the United States (U.S.). The burden of diabetes and its complications can be reduced by identifying those at high risk and routing them to treatment and intensive behavioral interventions. Aim: The aim of this study is to develop and validate a simple score to identify undiag-nosed diabetes among Hispanics living in the U.S. Methods: A representative sample of Hispanics living in the U.S. was used to develop and validate the score. Logistic regression was used to identify significant risk factors and model coefficients were used to …

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An Unusual Consequence Of Alcoholism And Recurrent Pancreatitis, Mrudula Thiriveedi, Suresh Karne, Parekha Yedla

UAB Huntsville Research Day - All Presentations

2019 clinical vignette poster

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Watch Your Children Grow: Learning How To Address Obesity In Underserved Populations, Meredith Lewis, Denise Surina-Baumgartner, Shivani Malhotra, Rajalakshmi Cheerla

UAB Huntsville Research Day - All Presentations

2019 oral presentation

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Geographic Proximity To Healthy Food Not Associated With Increased Prevalence Of Cardiovascular Risk Factors In Stroke Patients, Alan D. Howard, Chigozirim Izeogu, Adeniyi J. Idigo, Michael J. Lyerly

UAB Huntsville Research Day - All Presentations

2019 research poster

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Biopsychosocial Correlates Of Pain In Youth With Eosinophilic Esophagitis: A Comparison To Other Pediatric Patients, Mary Kenna Lynch

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EoE is a chronic, clinico-pathological, esophageal disease with symptoms that include dysphagia, reflux, vomiting, feeding aversion, and epigastric pain. Diagnosis requires clinical symptom presentation and histologic findings of eosinophil-predominant inflammation of the esophagus. While the pediatric patient’s epigastric pain is predictive of their quality of life, little is known about their pain experience. Through two studies, the pain experience, sleep quality, and internalizing symptoms of youth with Eosinophilic Esophagitis (EoE) have been examined. Through individually evaluating each of these factors as well as testing their relations with each other, the model proposed by Lynch and colleagues (2015) to understand the …

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Occupational Therapy Students’ Perceptions Of Individuals With Mental Illness Before And After A Service-Learning Experience, Valley Mccurry

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Service-learning is a pedagogical approach that allows occupational therapy students to engage in experiential learning with individuals who have mental illness. Perceptions of individuals with mental illness are influenced by factors such as societal stigma. Stigma is present among allied health professionals and students, including occupational therapy students, which may influence provision of care. In order to assess occupational therapy students’ level of comfort with the mental health population, this study used a convergent mixed methods approach to evaluate how students’ personal beliefs and self-efficacy changed after a service-learning experience at a homeless shelter. The study explored occupational therapy students’ …

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The Role Of The Built Environment In Transforming Underserved Neighborhoods Into Smart And Connected Communities, Mary Claire Nabors

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The goal of this report is to create a model for transforming underserved neighborhoods into smart, connected, healthy, and sustainable communities by focusing on the built environment. To do this, there must be a thorough neighborhood analysis of the existing conditions with recommendations for what needs to be done, both short term and long term. The built environment impacts many aspects of a neighborhood and the quality of life for residents. Sidewalks, streets, lighting, landscaping, and accessibility are all components of the built environment and research has continuously shown how the deterioration of the built environment affects the health and …

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Effects Of A Ketogenic Diet On Body Composition, Metabolic Health, And Quality Of Life In Ovarian And Endometrial Cancer Patients, Caroline Whitney Cohen

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Ketogenic diets (KDs) have garnered considerable research attention in recent years, having been investigated as a therapy for neurologic, metabolic, and even dermatologic diseases. Recent research has also focused on KDs as a potential intervention for cancer, with preclinical studies demonstrating profound effects such as inhibiting tumor growth, enhancing the effects of radiation and chemotherapy, and prolonging survival. However, to date few studies have been conducted in cancer patients. In order to determine if KDs might augment existing cancer treatment protocols, additional research is needed. Accordingly, the objective of this project was to conduct the first randomized, controlled trial examining …

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Examining The Role Of The Unfolded Protein Response In Depression, Matthew Timberlake

All ETDs from UAB

Depression is the leading cause of disability worldwide and impacts nearly 350 million people with a disproportionate representation in women with a 1:1.7 ratio of occurrence compared to men. This disorder is characterized by shifts in mood to include feelings of hopelessness, sadness, and lethargy as well as changes in diet, motivation, and sleep patterns. Further, over 50% of patients who struggle with depression also have suicidal ideation and as many as 10% of those commit suicide. At present, treatment plans include behavioral therapy (often) in conjunction with antidepressant medications which act on monoamines and their circuits in the central …

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Discovering The Genetic Architecture Underlying Exercise Response Using Drosophila Melanogaster, Louis P. Watanabe

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The growth of modern jobs, technology, and transportation has coincided with increased sedentary behavior in many developed nations. In the United States, this increase has contributed partially to rising rates of obesity, leading to more than 78 million obese individuals. The annual medical costs associated with obesity are thought to range from 147 to 210 billion dollars. The initial treatment recommendations for individuals with obesity are increased exercise and changes in diet. Despite the strong narrative pushing exercise as a health benefit, individual responses can vary widely, and little is known regarding the genetic networks modulating exercise response. In order …

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Examining Web-Based Lifestyle Interventions For Cancer Survivors, Victoria Williams

All ETDs from UAB

Diet, physical activity, and body weight status are important modifiable risk factors for many health outcomes among cancer survivors, including cancer recurrence. Face-to-face, print, and mailed lifestyle interventions have been used to promote behavior change in cancer survivors successfully. However, such approaches are costly and have limited reach. Web-based lifestyle interventions represent a promising solution to this public health concern. Therefore, this project involved first reviewing and identifying gaps in the existing literature in this area and then developing and pilot testing a web-based lifestyle intervention for cancer survivors. For this three-part dissertation, study 1 was a narrative review of …

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Genetic And Epigenetic Underpinnings Of End-Stage Human Heart Failure, Mark Emile Pepin

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Heart failure (HF) is the clinical endpoint of numerous diseases that negatively impact the heart’s capacity to pump and/or fill with blood. A variety of genetic and environmental factors have been identified as critical determinants of HF susceptibility; however, these factors cannot independently explain the phenotypic diversity of human HF. Instead, a complex interplay has been theorized to exist between genetics and the environment, although the molecular underpinnings of this synergy remain poorly understood. Of the possible mechanisms, epigenetic influences are uniquely capable of explaining how acute stressors of the cardiac microenvironment trigger the stable – yet reversible – reprogramming …

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Designing And Implementing Inclusive Community-Based Health Promotion Intiatives, Cassandra Herman

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Background: People with disabilities (PWDs) have poorer health outcomes, yet are they are underserved by public health initiatives. PWDs face numerous barriers to participation in community-based health programs despite mounting evidence about these barriers along with recommendations and guidelines to become more inclusive of disability. Policy, system, and environmental (PSE) changes that are inclusive of PWDs can help create access to health promotion programs for PWDs. Systematically implementing inclusive PSE changes using implementation science principles can support effective and sustainable changes are implemented for each unique community context. The purpose of this dissertation is to explore the experiences of public …

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Effectiveness Of Cardiopulmonary Rehabilitation On The Functional Capacity Of Cardiac Patients One-Year Post Rehab, Danish Gulamani

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ABSTRACT Cardiac rehabilitation (CR) programs are designed to improve functional capacity, quality of life, reduce cardiovascular risk factors, and improve psychosocial well-being through lifestyle management strategies. While CR programs effectively reduce cardiovascular disease (CVD) risk factors and improve functional capacity at discharge, little is known regarding long-term lifestyle behavior changes and changes in functional capacity that occur following discharge. PURPOSE: Examine changes in 6-minute walk distance (6MWD) 11-15 months following discharge from CR to evaluate long-term changes in functional capacity. METHODS: Patients who completed 24-36 sessions and 6-minute walk tests [6MWT, intake, discharge, and post-discharge (11-15 months following discharge)] between …

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The Weight Of Social Relationships: Social Network Analysis In An Adult Weight Loss Program, Alena Borgatti

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Adult behavioral obesity interventions often show improved attendance and weight loss when delivered in a group, as opposed to individual, therapy format. However, research on the exact mechanisms through which group therapy confers additional weight loss is lacking. Pediatric obesity interventions have recently begun to utilize social network analysis (SNA) to identify structural ties that may improve adherence and weight loss; however, this research is limited and has yet to be replicated in an adult weight loss program. The current study is the first to evaluate social networks in an adult behavioral weight loss intervention. Four weight loss groups were …

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Social Support And Self-Care Efficacy As Mediators Of Racial Disparities In Diabetes Health In Older Adults, Wesley Browning

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Diabetes is a health problem that affects millions of Americans annually, and Black Americans have a higher prevalence with more complications than White Americans. A disparity exists between Black and White older adults living with diabetes in distress related to symptoms, treatment, and complications associated with the disease. Additionally, there are differences in levels of performing diabetes self-care behaviors between Blacks and Whites. One series of factors that may predict better diabetes self-care and diabetes distress in older adults are self-care efficacy and components of social support. This study used linear regression models to predict racial differences between Blacks and …

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Associations Between Dietary Fat Intake And Waist Circumference, Phonchit Teng Soukhamneut

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The objective of this study was to assess: 1) trends in dietary fat intake from 2003-2016 2) the association between type of dietary fat intake and waist circumference (WC), 3) the association between type of dietary fat intake and body shape, and 4) whether these associations vary by sex and race/ethnicity. This secondary data analysis included 27,057 adults aged 19 to 65 from the National Health and Examination Survey (NHANES) 2003-2016. For WC, participants were categorized into high-risk (men: WC ≥ 40 in; women: WC ≥ 35 in) and low-risk (men: WC < 40 in; women: WC < 35 in). Total fat intake was categorized as high (TOTFAT ≥ 35%) and low (TOTFAT< 35%). Saturated fat intake was categorized into high (SATFAT ≥ 10%) and low (SATFAT < 10%). Unsaturated fat intake was categorized into high (UNSATFAT ≥ 25%) and low (UNSATFAT < 25%). Logistic regression was performed to assess the associations between DFI and WC and DFI and body shape, controlling for age, BMI, and total caloric intake. NHW men with high TOTFAT were found to have 1.41 (OR: 1.41, 1.19 – 1.68) times the odds of having a high-risk WC compared to men with a diet low in TOTFAT, controlling for age, BMI, and total caloric intake. NHW men with a diet high in SATFAT were at increased odds of having a high-risk WC compared to men with a diet low in SATFAT, after controlling for covariates (OR: 1.49, 1.21 -1.84). NHW men with a diet high in UNSATFAT were at increased odds of having a high-risk WC compared to men with a diet low in UNSATFAT after controlling for covariates (OR: 1.375, 1.09 – 1.74). There were no significant associations found among NWB and MA men for any type of dietary fat intake. For women, no associations were found between type of dietary fat and WC by race/ethnicity. There were no associations between DFI and body shape by race/ethnicity groups and sex. Future studies are needed to further investigate the body shape cut-off points for increased risk associated with chronic disease.

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Methods For The Establishment Of A Dss-Induced Ibd Model In Adult Zebrafish, Ningxiang Zeng

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Inflammatory Bowel Disease (IBD) is a group of idiopathic chronic inflammatory intestinal conditions. To reveal its pathogenesis, several different animal models have been established. Although no single model captures the complexity of human IBD, each model provides valuable insights into one or another major aspect of disease, and together they have led to the establishment of a generally accepted understanding for human IBD pathogenesis. Recently, zebrafish have become an important platform for IBD research, and several murine IBD outcomes have been adapted to the zebrafish. Dextran Sulfate Sodium (DSS) -induced colitis, the most widely used murine IBD model, has never …

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Exploring The Link Between Dietary Fiber, The Gut Microbiota And Estrogen Metabolism Among Women With Breast Cancer, Ayse G. Zengul

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Breast cancer continues to be a very prevalent disease and impacts over 260,000 new patients per year in the United States. The gut microbiota composition may affect breast cancer risk by modulating various hormonal metabolites including endogenous estrogens. Dietary factors impact gut microbial ecology and influence the regulation of estrogen metabolism. Current evidence supports the potential role of dietary fiber in breast cancer prevention and its possible modulating influence on serum estrogen levels through the gut microbiota associated with β-glucuronidase activity. However, this mechanism is not clearly understood. In this study, we aimed to explore the associations between dietary fiber, …

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The Mechanism Of Glucose-Induced Trib3 Expression In Myoblasts And Myotubes, Xiaobing Liu

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Our previous data indicates that glucose-toxicity is dependent upon upregulation of TRIB3 expression in muscle. TRIB3 is a glucose-responsive gene and, as a pseudokinase, it blocks phosphorylation of AKT resulting in insulin resistance. The purpose of the current study was to identify the role of the differentiation process and the minimal functional sequence of TRIB3 promoter region in modulating glucose-induced TRIB3 gene expression in C2C12 myocytes. First, C2C12 myocytes were collected every 48 hours during the whole differentiation, totally 4 intervals. Before collection, cells were treated with either 5mmol glucose or 25mmol glucose for 24 hours. Under 5mmol glucose, the …

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Utilization Of The Zebrafish Model System To Predict Effects Of Dietary Lipid Composition On Human Health, Lauren Adele Fowler

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Obesity is a disease that encompasses the interaction of both genetics and life-style factors, and the pathology behind its development remains unclear. Specifically, defining the influence of dietary lipid intake on adiposity and metabolic health continues to be a fundamental challenge, and the use of animal models will be required to gain a full understanding of the processes contributing to diet-induced obesity in humans. The zebrafish Danio rerio has emerged as a powerful model system to study diet-induced obesity and metabolic disease in humans, while simultaneously offering multiple advantages over rodent models. This dissertation addresses multiple aspects regarding the use …

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Full-Text Articles in Entire DC Network

Uab Team Wants To Build A Roadmap To A Model City, Matt Windsor

Browse All News

The Best And Worst Things You Can Do For Your Heart, Staff

Browse All News

Weight Cycling Does Not Adversely Affect Cardiovascular Outcomes In Women With Suspected Myocardial Ischemia, Adam Pope

Browse All News

Baskin Selected As President Of The Jefferson County Health Action Partnership, Staff

Browse All News

Recruitment Begins For New Study Examining Diet As Treatment For Type 2 Diabetes Patients, Staff

Browse All News

$3.25 Million R01 Grant Will Explore The Long-Term Impact Of Diet, Exercise On Symptoms Of Adults With Hiv, Staff

Browse All News

Does A Smart Fitness Device Or App Help You Lose Weight?, Alicia Rohan

Browse All News

Uab Magazine - Summer 2019, University Of Alabama At Birmingham

UAB Magazine

Dental Dimensions In Non-Syndromic Patients With Unilateral Cleft Palate, Blake Boleware

All ETDs from UAB

Assessing Diabetes Risk Among Hispanic Populations: Development And Validation Of A Risk Score Using Readily Available Information, Lucia Juarez

All ETDs from UAB

An Unusual Consequence Of Alcoholism And Recurrent Pancreatitis, Mrudula Thiriveedi, Suresh Karne, Parekha Yedla

UAB Huntsville Research Day - All Presentations

Watch Your Children Grow: Learning How To Address Obesity In Underserved Populations, Meredith Lewis, Denise Surina-Baumgartner, Shivani Malhotra, Rajalakshmi Cheerla

UAB Huntsville Research Day - All Presentations

Geographic Proximity To Healthy Food Not Associated With Increased Prevalence Of Cardiovascular Risk Factors In Stroke Patients, Alan D. Howard, Chigozirim Izeogu, Adeniyi J. Idigo, Michael J. Lyerly

UAB Huntsville Research Day - All Presentations

Biopsychosocial Correlates Of Pain In Youth With Eosinophilic Esophagitis: A Comparison To Other Pediatric Patients, Mary Kenna Lynch

All ETDs from UAB

Occupational Therapy Students’ Perceptions Of Individuals With Mental Illness Before And After A Service-Learning Experience, Valley Mccurry

All ETDs from UAB

The Role Of The Built Environment In Transforming Underserved Neighborhoods Into Smart And Connected Communities, Mary Claire Nabors

All ETDs from UAB

Effects Of A Ketogenic Diet On Body Composition, Metabolic Health, And Quality Of Life In Ovarian And Endometrial Cancer Patients, Caroline Whitney Cohen

All ETDs from UAB

Examining The Role Of The Unfolded Protein Response In Depression, Matthew Timberlake

All ETDs from UAB

Discovering The Genetic Architecture Underlying Exercise Response Using Drosophila Melanogaster, Louis P. Watanabe

All ETDs from UAB

Examining Web-Based Lifestyle Interventions For Cancer Survivors, Victoria Williams

All ETDs from UAB

Genetic And Epigenetic Underpinnings Of End-Stage Human Heart Failure, Mark Emile Pepin

All ETDs from UAB

Designing And Implementing Inclusive Community-Based Health Promotion Intiatives, Cassandra Herman

All ETDs from UAB

Effectiveness Of Cardiopulmonary Rehabilitation On The Functional Capacity Of Cardiac Patients One-Year Post Rehab, Danish Gulamani

All ETDs from UAB

The Weight Of Social Relationships: Social Network Analysis In An Adult Weight Loss Program, Alena Borgatti

All ETDs from UAB

Social Support And Self-Care Efficacy As Mediators Of Racial Disparities In Diabetes Health In Older Adults, Wesley Browning

All ETDs from UAB

Associations Between Dietary Fat Intake And Waist Circumference, Phonchit Teng Soukhamneut

All ETDs from UAB

Methods For The Establishment Of A Dss-Induced Ibd Model In Adult Zebrafish, Ningxiang Zeng

All ETDs from UAB

Exploring The Link Between Dietary Fiber, The Gut Microbiota And Estrogen Metabolism Among Women With Breast Cancer, Ayse G. Zengul

All ETDs from UAB

The Mechanism Of Glucose-Induced Trib3 Expression In Myoblasts And Myotubes, Xiaobing Liu

All ETDs from UAB

Utilization Of The Zebrafish Model System To Predict Effects Of Dietary Lipid Composition On Human Health, Lauren Adele Fowler

All ETDs from UAB