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Making The Most Of Your Groceries During The Coronavirus Pandemic, Adam Pope Apr 2020

Making The Most Of Your Groceries During The Coronavirus Pandemic, Adam Pope

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No abstract provided.


Apply For Fellowship To Enrich Student Experiences In The Honors College, Haley Herfurth Apr 2020

Apply For Fellowship To Enrich Student Experiences In The Honors College, Haley Herfurth

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No abstract provided.


Eating Right And Eating Smart During Covid-19, Adam Pope Mar 2020

Eating Right And Eating Smart During Covid-19, Adam Pope

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No abstract provided.


Online Teaching Veterans Share Their Top Tips, Matt Windsor Mar 2020

Online Teaching Veterans Share Their Top Tips, Matt Windsor

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No abstract provided.


Uab's Women & Infants Center Celebrates 10 Years In State-Of-The-Art Building, Alicia Rohan Mar 2020

Uab's Women & Infants Center Celebrates 10 Years In State-Of-The-Art Building, Alicia Rohan

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No abstract provided.


Hydrogen Sulfide Heightens Disease In Tuberculosis, Suggesting A New Therapeutic Target, Jeff Hansen Mar 2020

Hydrogen Sulfide Heightens Disease In Tuberculosis, Suggesting A New Therapeutic Target, Jeff Hansen

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No abstract provided.


New Study Calculates Damage Of Food And Lifestyle Choices On Inflammation, Staff Feb 2020

New Study Calculates Damage Of Food And Lifestyle Choices On Inflammation, Staff

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No abstract provided.


8 Wallet-Friendly Ways To Eat Foods That Are Good And Good For You, Staff Feb 2020

8 Wallet-Friendly Ways To Eat Foods That Are Good And Good For You, Staff

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No abstract provided.


How To Train For A Marathon, Staff Jan 2020

How To Train For A Marathon, Staff

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No abstract provided.


Step Up To Wellness With Uab On Feb. 5, Staff Jan 2020

Step Up To Wellness With Uab On Feb. 5, Staff

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No abstract provided.


Wednesdays Are All About Eating Well, Haley Herfurth Jan 2020

Wednesdays Are All About Eating Well, Haley Herfurth

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No abstract provided.


Wellness Tips To Get You Over The New Year's Resolution Slump, Adam Pope Jan 2020

Wellness Tips To Get You Over The New Year's Resolution Slump, Adam Pope

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No abstract provided.


'Proud To Be A Part Of Uab's Impact': What Employees Get When They Give Back, Matt Windsor Jan 2020

'Proud To Be A Part Of Uab's Impact': What Employees Get When They Give Back, Matt Windsor

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No abstract provided.


Learn How To Set Goals In The New Year With Uab's First Twitter Q&A, Adam Pope Jan 2020

Learn How To Set Goals In The New Year With Uab's First Twitter Q&A, Adam Pope

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No abstract provided.


Uab Magazine - Spring/Summer 2020, University Of Alabama At Birmingham Jan 2020

Uab Magazine - Spring/Summer 2020, University Of Alabama At Birmingham

UAB Magazine

No abstract provided.


Clinical Evaluation Of The Temporomandibular Joint Function Using 4d Jaw Tracking Following Total Joint Replacement, Farhana Rahman Jan 2020

Clinical Evaluation Of The Temporomandibular Joint Function Using 4d Jaw Tracking Following Total Joint Replacement, Farhana Rahman

All ETDs from UAB

The degenerative temporomandibular joint diseases such as osteoarthritis, rheumatic arthritis, TMJ ankylosis, condylar resorption is successfully treated by total joint replacement. The aim of this study was to examine the function of Temporomandibular joint after total joint replacement. 15 patients with unilateral or bilateral TMJ total joint replacements and 15 healthy controls were evaluated via SICAT JMT+ device. This non-invasive system measures 3D position and rotation in all degrees of freedom and allows undisturbed functional mandibular movements to provide a quantitative evaluation. In addition, a TMJ questionnaire consisting the subjective symptoms was also obtained. Mandibular movements after total joint replacements …


Exploring The Physical And Mental Health Disparities In The Transgender Male Community In A Southern Community-Based Medical Lgbtq Organization, Karen E. Musgrove Jan 2020

Exploring The Physical And Mental Health Disparities In The Transgender Male Community In A Southern Community-Based Medical Lgbtq Organization, Karen E. Musgrove

All ETDs from UAB

This dissertation examined the physical and mental health disparities in the transgender male community in a Southern community-based medical LGBTQ (lesbian, gay, bisexual, transgender, queer) organization via a convergent mixed methods study design. There is a paucity of research on the transgender male community in terms of their physical and mental health care needs, services, and disparities. Quantitative data were col-lected via a chart review of 130 transgender male medical charts at the Magic City Well-ness Center (MCWC). The MCWC transgender male medical chart data were compared to three groups separately of the 2018 Behavioral Risk Factor Surveillance System (BRFSS) …


Circadian Clock And Lipid Metabolism Disruption In Fatty Liver Disease, Jennifer Valcin Jan 2020

Circadian Clock And Lipid Metabolism Disruption In Fatty Liver Disease, Jennifer Valcin

All ETDs from UAB

Hepatic Steatosis, characterized by the accumulation of triglyceride (TG) in the liver is the first stage of Alcoholic Liver Disease (ALD) and Nonalcoholic Fatty Liver Disease (NAFLD). Many metabolic pathways, including lipid metabolism, are regulated by the molecular circadian clock. Importantly, alcohol consumption and obesity induce circadian clock disruption, a risk factor for many diseases, including liver disease. In our first study, we investigated the combined effect of clock disruption and alcohol feeding on liver pathology, and diurnal rhythms in the liver molecular clock and lipid metabolism. Male liver-specific Bmal1 knockout (LKO) mice and control littermates were fed a control …


Direct Primary Care In Rural Communities, Dusty Trotman, David Bramm Jan 2020

Direct Primary Care In Rural Communities, Dusty Trotman, David Bramm

UAB Huntsville Research Day - All Presentations

2020 research poster


Prolonged Conversion Disorder: Exacerbated By Misdiagnosis?, William Nolan, Tarak Vasavada Jan 2020

Prolonged Conversion Disorder: Exacerbated By Misdiagnosis?, William Nolan, Tarak Vasavada

UAB Huntsville Research Day - All Presentations

2020 clinical vignette poster


Contribution Of Adaptive Immune Responses In Chronic Lung Diseases, Thi Kim Tran-Nguyen Jan 2020

Contribution Of Adaptive Immune Responses In Chronic Lung Diseases, Thi Kim Tran-Nguyen

All ETDs from UAB

Immune dysregulation is a hallmark of various chronic lung diseases such as Chronic Obstructive Pulmonary Diseases (COPD) and Idiopathic Pulmonary Fibrosis (IPF). Previous studies in our lab have shown evidences of autoimmunity such as increases in autoantibodies, abnormal T cell profile, immune complex deposition and the presence of ectopic lymphoid structures in the lung of these patients. This thesis consolidates two separate projects about various aberrant immune responses in these diseases. The first project identified Glucose-Regulated-Protein 78 (GRP78) as the common autoantigen in COPD and characterized how GRP78 autoantibodies may increase COPD mortality via its atherogenic effects. I demonstrated that …


Understanding Financial Hardship In Women With Breast Cancer, Courtney Williams Jan 2020

Understanding Financial Hardship In Women With Breast Cancer, Courtney Williams

All ETDs from UAB

Individuals with cancer are at risk of material, psychological, and behavioral financial hardship due to costly new treatments, increasing time on treatment, and longer survival. Breast cancer is an ideal environment to study financial hardship. Treatment options for metastatic breast cancer are heterogeneous due to differences in patient characteristics, disease biology, and because it has the largest number of treatment options of any metastatic cancer. In early stage breast cancer, treatment options include multimodality treatments, including surgery, radiation, and medical therapy (chemotherapy, hormone therapy, targeted therapy), with the choice for each modality being dependent on the other modality decisions. Despite …


Assessment Of Emergency Department High Utilizer Program In Public Health System Setting, Michael Malaise Jan 2020

Assessment Of Emergency Department High Utilizer Program In Public Health System Setting, Michael Malaise

All ETDs from UAB

is study examined whether a case management model designed to reduce emergency department utilization among patients described as super-utilizers in a public health system could also reduce the per patient cost of those super-utilizers. The setting for this study was a large public health system in a major metropolitan area. The study focused on a low-income, urban population. Given the program’s stated desire to improve the self-efficacy of patients over time so that they could take more ownership of their own health status, this study reviewed the program within the framework of self-efficacy theory. This research predicted that the case …


Molecular Regulation Of Glioblastoma Spatial Heterogeneity And Therapeutic Resistance, Soniya Bastola Jan 2020

Molecular Regulation Of Glioblastoma Spatial Heterogeneity And Therapeutic Resistance, Soniya Bastola

All ETDs from UAB

Glioblastoma multiforme (GBM) is a highly invasive, highly vascularized, and heterogeneous malignant tumor of the brain. Due to the highly infiltrative phenotype of GBM, surgery often leaves behind residual tumor cells. In many cases, recurrence occurs close to the surgical margin suggesting the role of these remaining cells in promoting tumor aggressiveness. Rapidly growing tumor creates subsequent hypoxic, and hypovascular core due to limited nutrients, whereas tumor cells in the leading edge have access to nutrients from vasculature enriched microenvironment. Studies have identified the cellular and molecular heterogeneity between the tumors in core and edge. Still, their mechanisms of intercellular …


Race, Type Ii Diabetes Mellitus And Vertebral Fragility Fractures: A Cross-Sectional Analysis From Nhanes, Yuchen At Xiao Jan 2020

Race, Type Ii Diabetes Mellitus And Vertebral Fragility Fractures: A Cross-Sectional Analysis From Nhanes, Yuchen At Xiao

All ETDs from UAB

IntroductionThis study examined the association between race and bone health, and if T2DM modifies this association in a diverse sample of adults. Methods We conducted a cross-sectional study using the 2013-2014 National Health and Nutrition Examine Survey (NHANES) data. Bone health outcomes included lumbar spine BMD (lowered BMD based on T-scores <-1), and vertebral deformities, assessed via vertebral fracture assessment (VFA), including presence, number of deformities, and severity ratio of deformities. T2DM status and other demographic, lifestyle, and health characteristics were self-reported via questionnaire data. To assess if T2DM modifies the association between race and bone health outcomes, we conducted stratified analyses using logistic regression for dichotomous outcomes, Poison regression for count outcomes, and linear regression for continuous outcomes. Results Non-Hispanic (NH) Blacks have significantly less odds of being lowered BMD and osteoporosis comparing to NH-Whites in the crude model and significantly less odds of having vertebral deformities comparing to NH-White in both crude and adjusted model for non-diabetic participants. Such differences are not observed in diabetic groups. Participants in Other race group have significantly more odds of being lowered BMD comparing to NH-Whites in the adjusted model for both diabetic and non-diabetic groups. And have significantly more odds of having vertebral deformities in the diabetic group, crude and adjusted, yet the differences are not significant in non-diabetic groups. Similar results were seen in the number of deformities and total bone loss ratio. The potential modification effect of T2DM was not significant in these models. Conclusions In our national evaluation, bone health differs not only by race and ethnic group but also by T2DM status. The protective vertebral fragility effects observed among NH-Blacks was no longer present among those with diabetes. Likewise, among participants in other racial and ethnic groups, T2DM seemed to magnify the association of worse vertebral fragility. Such trends indicate a potential modifying effect of participants’ T2DM status and should be noted clinically, yet more studies are required for more precise results.


A Modified Standard American Diet (Msad) Induces Physiological Parameters Associated The With Metabolic Syndrome In C57bl/6j Mice, Sophie Bru Chehade Jan 2020

A Modified Standard American Diet (Msad) Induces Physiological Parameters Associated The With Metabolic Syndrome In C57bl/6j Mice, Sophie Bru Chehade

All ETDs from UAB

Obesity manifests physiologically in multiple organ systems of the body, typically increasing the risk of developing cardiometabolic disorders. Researchers have questioned the causative role that western dietary patterns have on disease pathogenesis and have speculated that quality and quantity of dietary fats and/or carbohydrates have a predictive role in the development of these disorders. Standard reference diets such as the AIN-93 rodent diet have historically been used to promote optimal animal model health and reduce variation of results across experiments. These diets have been invaluable to murine research; however, their translational value in studying human nutrition-related pathologies is limited. Early …


Impact Of Diet And Meal Timing On Time-Of-Day Dependent Hippocampal Function, Jennifer Davis Jan 2020

Impact Of Diet And Meal Timing On Time-Of-Day Dependent Hippocampal Function, Jennifer Davis

All ETDs from UAB

Circadian rhythms are biological processes that cycle every ~24 hours and have allowed life to adapt for optimal function across the day. These rhythms are present in all tissues in the body and are coordinated to the light/dark cycle by the suprachiasmatic nucleus (SCN) in the hypothalamus. Along with active-rest cycles, cognitive performance fluctuates across the course of the day, peaking during the active phase. In addition to the light cycle, food and meal timing can provide signaling cues to extra-SCN tissues. Food access only during the inactive phase results in weight gain and memory impairment. High fat diet protocols …


Calibration Of Periodontal Diagnosis Among Participants Of Various Dental Education Levels, Shadi Alkhoury Jan 2020

Calibration Of Periodontal Diagnosis Among Participants Of Various Dental Education Levels, Shadi Alkhoury

All ETDs from UAB

ABSTRACT: The purpose of this project is to assess the level of calibration among dental students of two different education levels and postgraduate students of two different dental specialties during diagnosis and treatment planning of clinical cases with various levels of periodontal involvement, using the 2018 Classification of Periodontal and Peri-implant Diseases and Conditions. Fifty-seven second year dental students (D2), 45 fourth year dental students (D4), 17 orthodontic postgraduate students (OS) and 12 postgraduate periodontology (PS) students were presented with an anonymous survey of 10 different cases, each with 5 choices of diagnosis and 7 therapeutic approaches. Consensus diagnosis was …


Early Childhood Quality Of Education And Late-Life Cognitive Function In A Population-Based Sample From Puerto Rico, Cheyanne Celine Barba Jan 2020

Early Childhood Quality Of Education And Late-Life Cognitive Function In A Population-Based Sample From Puerto Rico, Cheyanne Celine Barba

All ETDs from UAB

In general, greater years of education is associated with reduced risk of cognitive impairment in older adulthood, but the strength of this association has been found to differ by study population. Additionally, quality of education is understudied, despite evidence that quality of education and, in turn, literacy, may be additional indicators of cognitive reserve. This thesis examined years of education, literacy, and childhood quality of education indicators in relation to late-life cognitive outcomes in an older Puerto Rican population. We hypothesized that greater years of education, literacy, and quality of childhood education would be positively associated with each other, as …


Self-Awareness Of Functional Deficits In Older Adults With Mild Cognitive Impairment, Kayla Ann Steward Jan 2020

Self-Awareness Of Functional Deficits In Older Adults With Mild Cognitive Impairment, Kayla Ann Steward

All ETDs from UAB

Performance of instrumental activities of daily living (IADLs) can become compromised in older adults with mild cognitive impairment (MCI). Poor self-awareness of deficits, also known as anosognosia, occurs in a substantial minority of those with MCI and varies in extent depending on the domain examined. This dissertation attempts to explain the inter- and intra-patient variability in anosognosia by examining (1) differences in objective IADL performance and self-awareness of functional difficulties between those with amnestic single- (-ASD) and multi-domain (-AMD) MCI, and by examining (2) the neuropsychological and (3) neuroanatomical correlates of anosognosia for IADLs in older adults across a broad …