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From Classrooms To Polluted Communities: Scientific Inquiry In Birmingham, Alabama And Beyond, Sarah Jeanne Adkins-Jablonsky Jan 2021

From Classrooms To Polluted Communities: Scientific Inquiry In Birmingham, Alabama And Beyond, Sarah Jeanne Adkins-Jablonsky

All ETDs from UAB

Nearly half of all U.S. students who declare science majors in college do not graduate with science degrees within six years. Improvements in science outcomes are linked with active-learning pedagogies such as Course-based Undergraduate Research Experiences (CUREs). However, despite the need for education reform particularly in Alabama, active-learning interventions are severely understudied in Alabama universities. Chapter 1 describes novel CUREs at four colleges in Birmingham, AL: The University of Alabama at Birmingham (UAB); Jefferson State Community College (JSCC), Samford University (SU), and Birmingham Southern College (BSC). Chapter 2 shows how an agar art CURE, The Art of Microbiology, impacts student …


Social Inclusion Among People With Mobility Limitations In The Global South, Shane Burns Jan 2021

Social Inclusion Among People With Mobility Limitations In The Global South, Shane Burns

All ETDs from UAB

An estimated 15% of the world’s population have a disability—roughly 80% of whom live in the Global South. People with disabilities experience profound social disparities that affect their quality of life and social inclusion. Due to the array of cultural perspectives and institutional capacities around the globe, provision of disability rights can come with its challenges. In many cultural contexts, people have moral beliefs about disability that result in shame. More medicalized beliefs toward disability are often the result of medical infrastructure that offers goods and services. Using a framework that arrays these moral and medical dimensions, I theorized that …


Service Profiles In Substance Use Disorder Treatment: The Role Of Institutional And Organizational Factors, Reena Joseph Kelly Jan 2021

Service Profiles In Substance Use Disorder Treatment: The Role Of Institutional And Organizational Factors, Reena Joseph Kelly

All ETDs from UAB

Substance use disorders (SUDs) are a growing crisis globally and in the US, and place an enormous health, social, and financial burden on the nation. To address the complex nature of SUDs, treatment typically involves a combination of different types of services to address the medical, behavioral and social needs of the patient and care is often delivered by specialized SUD treatment facilities. Despite recommendations for a broad suite of services, individual facilities vary in the specific services that they offer. This study examined whether and why systematic differences exist between treatment facilities based on their service mix and whether …


Characterization Of The Metabolic And Cognitive Features Of A Novel Alzheimer’S Disease Rat Model Along With Investigation Of Its Gut Microbiota Change Over Time, Akash Nagarajan Jan 2021

Characterization Of The Metabolic And Cognitive Features Of A Novel Alzheimer’S Disease Rat Model Along With Investigation Of Its Gut Microbiota Change Over Time, Akash Nagarajan

All ETDs from UAB

Alzheimer’s disease (AD) is currently the fifth highest cause of death in the United States and affects primarily individuals of very old age (>80 yrs.). Aging is known to be the biggest risk factor of AD. Recent studies have shown that AD patients have an altered gut microbiota composition. To investigate whether the Alzheimer’s disease pathology in the brain could drive gut microbiota changes during the adult and late life stage of the rat, we performed 16S ribosomal RNA sequencing on the fecal samples of the animals at 14 months and 20 months of age. We found a distinctive …


Embodied Fat Stigma And Health Beliefs About Exercise And Diet, Brie Scrivner Jan 2021

Embodied Fat Stigma And Health Beliefs About Exercise And Diet, Brie Scrivner

All ETDs from UAB

The purpose of this dissertation is to examine how individuals navigate the cultural mandate for thinness, which pressured individuals to pursue weight loss through exercise and restrictive diets. While sustainable weight loss is not probable for the majority of people, there are still significant physical and mental health benefits to be had from engaging in regular, enjoyable movement. For many, physical activity is an important component of a healthy lifestyle. It can improve quality of life for individuals regardless of weight, body size, chronic illness, or disability. However, many fitness facilities focus on weight loss as the most essential goal …


Neonatal Murine Cytomegalovirus Infection Disrupts Synapse Remodeling During Development, Jerome Moulden Jan 2021

Neonatal Murine Cytomegalovirus Infection Disrupts Synapse Remodeling During Development, Jerome Moulden

All ETDs from UAB

Human cytomegalovirus (HCMV) is a complex double stranded DNA betaherpesvirus. Its linear DNA in enclosed in an icosahedral capsid, and has a genome size of about 230kb and encodes about 170 genes. Primary infection with HCMV lead to a lifelong persistent infection. HCMV can also be transmitted across the placenta and infect the developing fetus leading to infection of the newborn infant, an infection which is commonly described as congenital HCMV infection. In the United States, the prevalence of congenital HCMV infection is between 0.2-1.2%. Approximately 5-15% of these newborn infants will develop long-term neurological damage resulting, motor disorder, cognition …


Multidrug-Resistance, Antibiotic-Associated Acute Kidney Injury, And Poor Disease Prognosis In Community-Acquired Bacterial Pneumonia, Adeniyi J. Idigo Jan 2021

Multidrug-Resistance, Antibiotic-Associated Acute Kidney Injury, And Poor Disease Prognosis In Community-Acquired Bacterial Pneumonia, Adeniyi J. Idigo

All ETDs from UAB

In this dissertation research, I examined the challenges of treating patients with bacterial community-acquired pneumonia (CAP) with the purpose of identifying risk factors linked with multidrug-resistant (MDR) Pseudomonas, treatment toxicity, and poor disease prognosis. I used a retrospective cohort study design to explore a clinical cohort of patients admitted to the University of Alabama at Birmingham hospital network who had bacterial pneumonia diagnosis assessed to be from community transmission between January 2013-December 2019. Electronic medical records were accessed for socio-demographic and clinical information. First, I examined the local prevalence/incidence of Pseudomonas CAP and MDR Pseudomonas CAP, and the relationship between …


Structural Changes To Desmosomal Architecture During Assembly And Maturation, Reena R. Beggs Jan 2021

Structural Changes To Desmosomal Architecture During Assembly And Maturation, Reena R. Beggs

All ETDs from UAB

Desmosomes are macromolecular junctions important in adhesion and resisting mechanical stress in epithelial and cardiac tissue. Desmosomes have a complex architecture with transmembrane cadherins, desmogleins and desmocollins, constituting the adhesive interface and plaque proteins, including plakoglobin and desmoplakin, binding the cadherin tails and integrating with intermediate filaments. Dysregulation of desmosomes occurs in many disease states, such as cardiomyopathies, skin diseases, and various cancers. While mature desmosomes' structure is generally understood, less is known about desmosome architecture during assembly and recycling. Desmosomes are dynamic, biochemically intractable, and diffraction-limited, making them challenging to study. To overcome these obstacles, I applied the super-resolution …


The Role Of Visa Status And Acculturation In The Health Of Us Immigrants, Serra Sevde Hatipoglu Jan 2021

The Role Of Visa Status And Acculturation In The Health Of Us Immigrants, Serra Sevde Hatipoglu

All ETDs from UAB

Using data from the 2003 New Immigrant Survey, I examined the association between visa status and acculturation with physical, mental, and self-rated health among immigrants residing in the United States. The primary predictor variable in the study is immigrant visa status. The outcome variables of interest include physical health as any morbidity (chronic diseases), mental health as depressed (as defined by the DSM-IV) and self-rated health (poor self-rated health). Using logistic regressions, I found those with unfavorable visa statuses have worse mental, physical, self-rated health compared to the favorable visa holders. I used inverse odds ratio weighted (IORW) mediation method …


Undergraduate Students’ Perspectives On Mental Health Services, Resources, And Supports During Covid-19: A Qualitative Dissertation, Amy Hutson Chatham Jan 2021

Undergraduate Students’ Perspectives On Mental Health Services, Resources, And Supports During Covid-19: A Qualitative Dissertation, Amy Hutson Chatham

All ETDs from UAB

During the COVID-19 pandemic, increased isolation from supportive relationships, uncertainty about the future, fear of illness, and lack of traditional life-events took a toll on university student mental health. It is important to understand undergraduate students’ mental health needs during the COVID-19 pandemic and their desires for support from their institutions of higher education. Existing studies have documented increased rates of depression, stress, and anxiety among university undergraduates; however, these studies rarely illuminate students’ perspectives on mental health services, resources, and supports that they need during and because of the COVID-19 pandemic. This phenomenological study explored the perspectives of undergraduate …


Sustained Cellular Immune Dysregulation In Individuals Recovering From Covid-19, Jeff Hansen Dec 2020

Sustained Cellular Immune Dysregulation In Individuals Recovering From Covid-19, Jeff Hansen

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No abstract provided.


Sustained Cellular Immune Dysregulation In Individuals Recovering From Sars-Cov-2 Infection, Mary Ashley Canevaro Dec 2020

Sustained Cellular Immune Dysregulation In Individuals Recovering From Sars-Cov-2 Infection, Mary Ashley Canevaro

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No abstract provided.


Uab's 1917 Clinic Officially Relocates To Lakeview District, Alicia Rohan Dec 2020

Uab's 1917 Clinic Officially Relocates To Lakeview District, Alicia Rohan

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No abstract provided.


School Of Medicine Vaccine Town Hall Overview, Mary Ashley Canevaro Dec 2020

School Of Medicine Vaccine Town Hall Overview, Mary Ashley Canevaro

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No abstract provided.


2020: The Year In Photos, Haley Herfurth Dec 2020

2020: The Year In Photos, Haley Herfurth

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No abstract provided.


What You Need To Know About The Pfizer Covid-19 Vaccine, Adam Pope Dec 2020

What You Need To Know About The Pfizer Covid-19 Vaccine, Adam Pope

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No abstract provided.


Covid-19 Vaccine Arrives At Uab Hospital, Alicia Rohan Dec 2020

Covid-19 Vaccine Arrives At Uab Hospital, Alicia Rohan

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No abstract provided.


Uab To Provide First Vaccine Doses To Front Line And Clinical Staff, Ems And Other Birmingham-Area Hospitals, Tyler Greer Dec 2020

Uab To Provide First Vaccine Doses To Front Line And Clinical Staff, Ems And Other Birmingham-Area Hospitals, Tyler Greer

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No abstract provided.


Student Insights: Meet Our Vital Signs Contributors, Uab Heersink School Of Medicine News Dec 2020

Student Insights: Meet Our Vital Signs Contributors, Uab Heersink School Of Medicine News

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No abstract provided.


Connection To Aphl National Key Server Extends Guidesafe™ App Capabilities Beyond State Lines, Tyler Greer Nov 2020

Connection To Aphl National Key Server Extends Guidesafe™ App Capabilities Beyond State Lines, Tyler Greer

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No abstract provided.


Survey Contributes To Ehr Changes; Promotes User Well-Being, Mary Ashley Canevaro Nov 2020

Survey Contributes To Ehr Changes; Promotes User Well-Being, Mary Ashley Canevaro

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No abstract provided.


Inspiring Teamwork During Unprecedented Times, Selwyn M. Vickers Md Nov 2020

Inspiring Teamwork During Unprecedented Times, Selwyn M. Vickers Md

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No abstract provided.


Keep Moving And Stay Connected: Tips For Taking Care Of Older Loved Ones During A Pandemic, Adam Pope Nov 2020

Keep Moving And Stay Connected: Tips For Taking Care Of Older Loved Ones During A Pandemic, Adam Pope

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No abstract provided.


How Can You Safely Return Home For The Holidays?, Alicia Rohan Nov 2020

How Can You Safely Return Home For The Holidays?, Alicia Rohan

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No abstract provided.


How To Enjoy Thanksgiving, Family Holidays During A Pandemic, Staff Nov 2020

How To Enjoy Thanksgiving, Family Holidays During A Pandemic, Staff

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No abstract provided.


How To Overcome Covid-19 Fatigue, Alicia Rohan Nov 2020

How To Overcome Covid-19 Fatigue, Alicia Rohan

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No abstract provided.


Fauci, Neuzil Explain What We've Learned About Covid-19 And Where We Stand On Vaccines, Matt Windsor Nov 2020

Fauci, Neuzil Explain What We've Learned About Covid-19 And Where We Stand On Vaccines, Matt Windsor

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No abstract provided.


Epidemiologist Answers Questions About What To Expect With Coronavirus Cases During The Holidays, Alicia Rohan Nov 2020

Epidemiologist Answers Questions About What To Expect With Coronavirus Cases During The Holidays, Alicia Rohan

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No abstract provided.


Flu And Covid-19: How To Tell The Difference This Winter And Stay Safe, Alicia Rohan Oct 2020

Flu And Covid-19: How To Tell The Difference This Winter And Stay Safe, Alicia Rohan

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No abstract provided.


Interdisciplinary Work Highlighted At Covid-19 Research Symposium, Jeff Hansen Oct 2020

Interdisciplinary Work Highlighted At Covid-19 Research Symposium, Jeff Hansen

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No abstract provided.