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University of Alabama at Birmingham

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Uab Libraries Q2 2025 Employee Updates, Uab Libraries Jun 2025

Uab Libraries Q2 2025 Employee Updates, Uab Libraries

UAB Libraries News

No abstract provided.


June 24, 2025 Ereporter, University Of Alabama At Birmingham Jun 2025

June 24, 2025 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


June 17, 2025 Ereporter, University Of Alabama At Birmingham Jun 2025

June 17, 2025 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


June 13, 2025 Ereporter, University Of Alabama At Birmingham Jun 2025

June 13, 2025 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


Understanding The Roles Of Individual And Family-Based Resilience Resources And Mechanisms In Youth With Painful Disorders Of Gut-Brain Interaction, Corinne Taylor Evans Jun 2025

Understanding The Roles Of Individual And Family-Based Resilience Resources And Mechanisms In Youth With Painful Disorders Of Gut-Brain Interaction, Corinne Taylor Evans

All ETDs from UAB

Background Children living with chronic pain are at risk for many negative physical and mental health consequences. However, certain positive attributes and factors can help lessen or prevent such consequences. Children with painful disorders of gut-brain interaction (DGBIs) experience deficits in social, emotional, and physical functioning. However, it is unknown whether a combination of individual and family-based resilience factors may lower these risks and contribute to improved physical and mental health responses. Methods 120 children with painful DGBIs were recruited from a pediatric gastroenterology clinic. Children and caregivers completed a series of questionnaires measuring individual and family-based resilience resources (e.g., …


June 11, 2025 Blazer Weekly, University Of Alabama At Birmingham Jun 2025

June 11, 2025 Blazer Weekly, University Of Alabama At Birmingham

Blazer Weekly (student newsletter)

No abstract provided.


June 10, 2025 Ereporter, University Of Alabama At Birmingham Jun 2025

June 10, 2025 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


June 6, 2025 Ereporter, University Of Alabama At Birmingham Jun 2025

June 6, 2025 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


The Bone Is Not Alone: Skeletal Muscle Is A Novel Source Of Fibroblast Growth Factor 23, Kylie Heitman Jun 2025

The Bone Is Not Alone: Skeletal Muscle Is A Novel Source Of Fibroblast Growth Factor 23, Kylie Heitman

All ETDs from UAB

Chronic kidney disease (CKD) is a major public health issue often accompanied by various pathologies. Hyperphosphatemia contributes to a range of complications, including vascular calcification, systemic inflammation, anemia, left ventricular hypertrophy, and skeletal muscle atrophy. Phosphate homeostasis is tightly regulated through a combination of renal excretion and its storage in bones, with fibroblast growth factor (FGF) 23 playing a central role in this regulation. Produced primarily by osteocytes in response to elevated serum phosphate, FGF23 helps maintain phosphate balance by promoting renal phosphate excretion and inhibiting the synthesis of vitamin D and parathyroid hormone. Dysregulation of FGF23 is associated both …


Translucency And Stain Resistance Of A Light Cured Pontic Paste, Ahmed Abumustafa Jun 2025

Translucency And Stain Resistance Of A Light Cured Pontic Paste, Ahmed Abumustafa

All ETDs from UAB

Objectives: Light-cured pontic pastes can be applied to the internal aspect of clear retainer/aligner trays at sites of missing teeth. Ideally, the pontic tooth should appear visually opaque and resist staining. The aim of this study was to determine if the number of coats of the paste will affect its translucency and stain resistance. Materials and Methods: 12mm diameter discs of a biocryl clear retainer material (Clear Splint) (n=10) were punch-cut. Light-cure pontic paste (Perfect-A-Smile Pontic) was applied to one side of the biocryl discs in 1, 2, 3 or 4 coats (200-400g /coat). The paste was light cured between …


Secondary Medical Conditions In Pediatric Survivors Of Acute Lymphoblastic Leukemia: Role In Performance-Based Neurocognitive Functioning, Caregiver-Reported Outcomes, And Adaptive Functioning And Transition Readiness Intervention, Victoria Seghatol-Eslami Jun 2025

Secondary Medical Conditions In Pediatric Survivors Of Acute Lymphoblastic Leukemia: Role In Performance-Based Neurocognitive Functioning, Caregiver-Reported Outcomes, And Adaptive Functioning And Transition Readiness Intervention, Victoria Seghatol-Eslami

All ETDs from UAB

Survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of secondary medical conditions arising from disease and treatment effects. Secondary medical conditions are associated with adverse survivorship outcomes (e.g., neurocognitive, psychosocial, and adaptive functioning/healthcare transition) in adult survivors of childhood ALL. Little is known about secondary medical conditions in pediatric ALL survivors. Further, the relationship between secondary medical conditions and survivorship outcomes has not been explored in this younger population. This dissertation examined 1) the role of secondary medical conditions in performance-based and caregiver-reported neurocognitive, psychosocial, and adaptive functioning; and 2) the roles of secondary medical conditions and neurocognitive …


Antifungal Efficacy And Flexural Strength Of Silver Nanoparticles Reinforced Cad/Cam And Heat-Cured Pmma Polymers: An In-Vitro Study, Himanshi Aggarwal Jun 2025

Antifungal Efficacy And Flexural Strength Of Silver Nanoparticles Reinforced Cad/Cam And Heat-Cured Pmma Polymers: An In-Vitro Study, Himanshi Aggarwal

All ETDs from UAB

Background: PMMA denture base resins have high propensity for C. albicans growth. Previous studies have found that silver nanoparticle (SNP) addition into conventional PMMA resin improves fungal resistance without interfering with its flexural strength. Recently, CAD/CAM dentures have become highly popular, but they are also prone to fungal in-growth. However, little is known about the effect of addition of silver nanoparticles in CAD/CAM printed PMMA resin material. Objective: To compare the effect of the addition of cytocompatible concentration (1 µm/ml) of SNP on the antifungal efficacy and flexural strength of CAD/CAM printed and heat-cured PMMA polymers. Materials and methods: A …


Balancing The Clinical Response To Sleep Disturbance In Adults 65 And Older, Katherine C. Ward Jun 2025

Balancing The Clinical Response To Sleep Disturbance In Adults 65 And Older, Katherine C. Ward

All ETDs from UAB

Older adults are more likely to have symptoms of insomnia than other age ranges. Ensuring an appropriate clinical response to insomnia in older adults is vital to their health and well-being. This paper addresses the assessment and treatment of insomnia symptoms in older adults in two separate studies analyzing data from the AMBulatoRy blOod preSsure In older Adults (AMBROSIA) study, which recruited older adults (≥65 years old) who had hypertension and were living in Southern California. The first study aimed to investigate the ability of the insomnia severity index (ISI), a standard self-report measure used to assess insomnia symptoms, to …


Autism Spectrum Disorder-Specific Knowledge And Self-Efficacy Among Early Interventionists In Alabama, Greta R. Conlon Jun 2025

Autism Spectrum Disorder-Specific Knowledge And Self-Efficacy Among Early Interventionists In Alabama, Greta R. Conlon

All ETDs from UAB

Young children diagnosed with autism and those who will go on to receive an autism diagnosis are frequently enrolled in early intervention services under Part C of IDEA. ASD-specific knowledge and self-efficacy have been shown to vary among providers working with autistic children, including those providing early intervention services (i.e., early interventionists). The current study aimed to characterize ASD-specific knowledge and self-efficacy in a sample of early interventionists in Alabama. In addition, it sought to identify differences in knowledge and self-efficacy between early interventionists serving different roles and to identify predictors of identified knowledge levels and self-efficacy ratings among participants. …


Development Of Aldot's Worker Safety Assessment, Risk Identification, And Control Program, Lana Marji Jun 2025

Development Of Aldot's Worker Safety Assessment, Risk Identification, And Control Program, Lana Marji

All ETDs from UAB

This research examines the safety challenges faced by Transportation Maintenance Technicians (TMTs) at the Alabama Department of Transportation (ALDOT). By ana-lyzing extensive injury data from 2009 to 2024, along with insights from surveys and interactions with ALDOT personnel, this effort highlights significant trends and relation-ships among injury characteristics such as nature, cause, source, and affected body parts. The findings reveal considerable costs and productivity losses associated with common injury types that warrant the need for targeted interventions. By reviewing successful safety programs across various state Departments of Transportation (DOTs), the study identifies opportunities to enhance safety within ALDOT. This effort …


June 3, 2025 Ereporter, University Of Alabama At Birmingham Jun 2025

June 3, 2025 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


Organizational Factors That Impact Emergency Room Sepsis Bundle Compliance In U.S. Hospitals, Jason Lee Kimbrell Jun 2025

Organizational Factors That Impact Emergency Room Sepsis Bundle Compliance In U.S. Hospitals, Jason Lee Kimbrell

All ETDs from UAB

ORGANIZATIONAL FACTORS THAT IMPACT EMERGENCY ROOM SEPSIS BUNDLE COMPLIANCE IN U.S. HOSPITALS JASON L. KIMBRELL HEALTH SERVICES ADMINISTRATION ABSTRACT This in-depth study examines the organizational factors within U.S. hospital emergency rooms (ERs) that impact care teams’ adherence to established, time-sensitive sepsis protocols. The regression analysis revealed a concerning trend: for each 1% increase in annual patient walk-out rates, compliance with sepsis protocols declines by 2.10%. Additionally, the impact on poor ER throughput where the ESI level 3 length of stay increases by 1 minute, a hospital's compliance with the 3hr POA sepsis bundle decreases by .08%. These findings underscore the …


Stroke Survivors: Predicting Cognitive Outcomes By Stroke Severity, Caregiver Factors, & Social Determinants Of Health, Jason Alexander Blake Jun 2025

Stroke Survivors: Predicting Cognitive Outcomes By Stroke Severity, Caregiver Factors, & Social Determinants Of Health, Jason Alexander Blake

All ETDs from UAB

Physical and cognitive disabilities are common following a stroke, often leading to significant changes in survivors' daily lives and increasing dependency on caregivers. These changes can include involuntary retirement, loss of independence, and decreased social engagement, which may necessitate adjustments in living arrangements and long-term care. This dissertation investigates the predictors of cognitive outcomes in stroke survivors, with a particular focus on the roles of stroke severity and caregiver factors. Utilizing data from the REasons for Geographic and Racial Differences in Stroke (REGARDS) project, this research captures the different predictors of post-stroke cognition through biennial assessments. Through longitudinal studies, this …


The Role Of B Cells In A Mouse Model Of Multiple System Atrophy, Gabrielle Childers Jun 2025

The Role Of B Cells In A Mouse Model Of Multiple System Atrophy, Gabrielle Childers

All ETDs from UAB

Multiple system atrophy (MSA) is a rare, fast progressing, debilitating and ultimately fatal movement disorder. The pathological hallmark of MSA disease is the aggregation and misfolding of alpha-synuclein (α-syn) protein in the cytoplasm of oligodendrocytes, termed glial cytoplasmic inclusions (GCIs). Accumulation of these GCIs result in progressive demyelination and neurodegeneration of the striatonigral and olivopontocerebellar regions of the brain. Currently, no therapeutics have been approved that slow or halt the progression of this devastating disease. Neuroinflammation, has been increasingly appreciated as a key neuropathological feature of disease, especially activation of tissue resident innate immune cells. Recently, evidence of adaptive immune …


Experiences Of Discrimination And Neighborhood Cohesion In Risk Of Poor Mental Health Outcomes Among Older, Community-Dwelling Participants In The Regards Study, Marquita S. Brooks Jun 2025

Experiences Of Discrimination And Neighborhood Cohesion In Risk Of Poor Mental Health Outcomes Among Older, Community-Dwelling Participants In The Regards Study, Marquita S. Brooks

All ETDs from UAB

Mental health disorders impact approximately 14% of persons aged 65 and older and often are undertreated or underrecognized. Assessment of factors that link environmental, sociocultural, behavioral, and biological factors to overall health and disease is integral to guiding research on health disparities in older populations. Although research suggests associations between environmental factors (i.e., discrimination and neighborhood cohesion) and mental health outcomes, there is limited research on these factors within the U.S. Therefore, our study assessed the relationship between discrimination, neighborhood cohesion, and mental health outcomes in the REasons for Geographic and Racial Differences in Stroke (REGARDS) study, a national, prospective …


Examining Risk And Protective Factors Of African Americans Who Use Substances, Dominique Ashonta Black Jun 2025

Examining Risk And Protective Factors Of African Americans Who Use Substances, Dominique Ashonta Black

All ETDs from UAB

African Americans (AAs) are less likely to report internalized symptoms and substance use compared to other racial groups but tend to report more severe symptoms related to either condition. Research suggests internalized symptoms and substance use share a causal relationship or an underlying factor that contributes to both conditions. Risk factors such as stress, discrimination, and trauma strengthen the relationship between anxiety and substance use in AAs. A higher prevalence of stress, discrimination, and trauma exposure was found in AAs when compared to other racial groups, increasing AAs risk for internalized symptoms and substance use. While it is important to …


Cardiac-Derived Fibroblast Growth Factor 23 Contributes To Physiologic And Pathologic Cardiac Remodeling, Isaac Daniel Campos Jun 2025

Cardiac-Derived Fibroblast Growth Factor 23 Contributes To Physiologic And Pathologic Cardiac Remodeling, Isaac Daniel Campos

All ETDs from UAB

Chronic Kidney Disease (CKD) is a global health risk that increases patients’ risk for premature mortality and is accompanied by pathologic cardiac hypertrophy and fibrosis. Declining kidney function results in elevations of serum phosphate and Fibroblast Growth Factor (FGF) 23, a bone-derived phosphaturic hormone. Hyperphosphatemia and elevated FGF23 are associated with cardiovascular mortality in CKD. FGF23 can directly target cardiac myocytes via FGF Receptor (FGFR) 4 and induce cardiac hypertrophy and blocking FGFR4 signaling in CKD models reduces cardiac hypertrophy, but not fibrosis. FGF23 elevations are also observed following exercise and during pregnancy, two scenarios of physiologic hypertrophy not associated …


News From Uab Libraries, 06 2025, Uab Libraries Jun 2025

News From Uab Libraries, 06 2025, Uab Libraries

UAB Libraries News

No abstract provided.


May 23, 2025 Ereporter, University Of Alabama At Birmingham May 2025

May 23, 2025 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


May 16, 2025 Ereporter, University Of Alabama At Birmingham May 2025

May 16, 2025 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


May 13, 2025 Ereporter, University Of Alabama At Birmingham May 2025

May 13, 2025 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


May 9, 2025 Ereporter, University Of Alabama At Birmingham May 2025

May 9, 2025 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

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May 6, 2025 Ereporter, University Of Alabama At Birmingham May 2025

May 6, 2025 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

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May 2, 2025 Ereporter, University Of Alabama At Birmingham May 2025

May 2, 2025 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


News From Uab Libraries, 05 2025, Uab Libraries May 2025

News From Uab Libraries, 05 2025, Uab Libraries

UAB Libraries News

No abstract provided.