Digital Commons Network^™

Blood Supplies Remain Low Nationwide. Please Donate., Alicia Rohan

Browse All News

No abstract provided.

January 10, 2023 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

January 6, 2023 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

January 4, 2023 Greenmail, University Of Alabama At Birmingham

GreenMail (student newsletter through 2024)

No abstract provided.

Uab Earns Women's Choice Award For "Best Hospital" Designation For Nine Areas, Hannah Echols

Browse All News

No abstract provided.

The Historical Roots Of Loneliness, Caleb Burnett

Vulcan Historical Review

pp. 66-74

The Limited Scope And Legacy Of The Doctors' Trial, Annie Foreman

Vulcan Historical Review

pp. 91-96

Hiv And Addiction Services For People Who Inject Drugs: Healthcare Provider Perceptions On Integrated Care In The U.S. South, Davis Bradford, Mariel Parman, Sara Levy, Wesli H. Turner, Li Li, Leah Leisch, Ellen Eaton, Kaylee B. Crockett

APC Fund

This qualitative study evaluates physician training and experience with treatment and prevention services for people who inject drugs (PWID) including medications for opioid use disorder (MOUD) and HIV pre-exposure prophylaxis (PrEP). The Behavioral Model of Healthcare Utilization for Vulnerable Populations was applied as a framework for data analysis and interpretation. Two focus groups were conducted, one with early career physicians (n = 6) and one with mid- to late career physicians (n = 3). Focus group transcripts were coded and analyzed using thematic analysis to identify factors affecting implementation of treatment and prevention services for PWID. Respondents identified that increasing …

Uab Magazine - Spring 2023, University Of Alabama At Birmingham

UAB Magazine

No abstract provided.

Provider Perspectives On Fertility And Fertility Preservation Discussions Among Women With Cystic Fibrosis, Jessica Corcoran, Caitlyn Campbell, Sigrid Ladores

APC Fund

Cystic Fibrosis (CF) is a genetic disorder that primarily impacts the respiratory and gastrointestinal systems. With advances in treatment and medications, the life expectancy of people with CF is continuing to increase with current life expectancy at 47 years of age. Given the increased life expectancy, people with CF are interested in childbearing but may have CF specific fertility issues that should be addressed by their CF healthcare provider. Currently, these conversations are not occurring or are suboptimal. This study aimed to investigate the practices of cystic fibrosis (CF) healthcare providers regarding fertility and fertility preservation (FP) discussions among women …

Uab Magazine - Fall/Winter 2023, University Of Alabama At Birmingham

UAB Magazine

No abstract provided.

Resources Availability And Covid-19 Mortality Among Us Counties, Josue Patien Epane, Ferhat Zengul, Zo Ramamonjiarivelo, Luceta Mcroy, Robert Weech-Maldonado

APC Fund

The COVID-19 was declared a pandemic by WHO on 03/2020 has claimed millions of lives worldwide. The US leads all countries in COVID-19-related deaths. Individual level (preexisting conditions and demographics) and county-level (availability of resources) factors have been attributed to increased risk of COVID-19-related deaths. This study builds on previous studies to assess the relationship between county-level resources and COVID-19 mortality among 2,438 US counties. We merged 2019 data from AHA, AHRF, and USA FACTS. The dependent variable was the total number of COVID-19-related deaths. Independent variables included county-level resources: (1) hospital staffing levels (FTE RNs, hospitalists, and intensivists) per …

Enhancement Of Muscle Shortening Torque Preloaded With Muscle Lengthening Is Joint-Specific, Marzouq K. Almutairi, Gary R. Hunter, Donald H. Lein, Sojung Kim, David R. Bryan, Mario Inacio, Christopher P. Hurt, William Reed, Harshvardhan Singh

APC Fund

Our cross-sectional study aimed to investigate joint specificity of concentric muscle torque enhancement after a maximum eccentric contraction for the knee versus ankle joints across two different movement velocities (120°/s and 180°/s). After a familiarization session, 22 healthy young adults randomly performed concentric (CONC) and maximum eccentric preloaded concentric (EccCONC) muscle strength tests of the knee extensors and ankle plantar flexors of the non-dominant leg on an isokinetic strength testing device. We calculated the ratio between EccCONC and CONC (EccCONC/CONC) for all the conditions as the marker of concentric muscle torque enhancement. Separate two-way (joints x velocity) within repeated measures …

Out Of Order By Alexis Sears, Stephen Kampa

Birmingham Poetry Review

pp. 214-221

Science, Sleep, And Surprises: My Path To The Most Promising Scientist Award, Cynthia Sanchez

Inquiro (undergraduate research journal)

pp. 7-8

https://www.uab.edu/inquiro/issues/past-issues/volume-11/science-sleep-and-surprises-my-path-to-the-most-promising-scientist-award

"A New Normal": The Making Of A Short Documentary On Childhood Cancer Survivorship, Britney Le, Victoria Sutton

Inquiro (undergraduate research journal)

pp. 9-11

https://www.uab.edu/inquiro/issues/past-issues/volume-11/a-new-normal-the-making-of-a-short-documentary-on-childhood-cancer-survivorship

Inquiro 11 (Complete Issue), Inquiro Staff

Inquiro (undergraduate research journal)

https://www.uab.edu/inquiro/issues/past-issues/volume-11

Dact1, The “Super-Crosslinker”: Regulation Of Non-Canonical Wnt Signaling During Vertebrate Convergent Extension By Modulating Dishevelled Oligomerization, Allyson Angermeier

All ETDs from UAB

A broad spectrum of human birth defects arise from the disruption of morphogenesis, the critical process through which tissues and organs acquire their proper shape. Convergent extension (CE) is a universal morphogenetic engine that promotes polarized extension of diverse tissues and organs by regulating directional cell behavior, such as oriented cell intercalation. In vertebrates, CE is regulated by non-canonical Wnt/Planar Cell Polarity (PCP) pathway, an ancient signaling pathway that was originally discovered to coordinate the cellular polarity in the plane of the epithelium. Non-canonical Wnt/PCP signaling shares the Frizzled (Fz) receptor and cytoplasmic signal transducer Dishevelled (Dvl) with the canonical …

Study Of The Processing-Structure-Property Relationship In Recycled Thermoplastic Composites, Carlos Gerardo Angulo Ruiz

All ETDs from UAB

The quest for sustainable materials and manufacturing techniques has spurred research into distinct composite materials that utilizes recycled thermoplastics in combination with natural hemp fibers and recycled carbon fibers. This dissertation delves into the processing of recycled high-density polyethylene (rHDPE) with hemp fiber and separately, with recycled carbon fiber (rCF), scrutinizing their suitability as environmentally friendly and economically viable materials. The study focuses on distinct processing methods used for hemp fiber and recycled carbon fiber: compression molding with hemp mats as well as extrusion compression molding, additive manufacturing, and injection molding for recycled carbon fiber, while the recycled carbon fiber …

Modifiable Risk Factors And Subsequent All-Cause And Cause-Specific Late Mortality After Blood Or Marrow Transplanta-Tion (Bmt), Nora Balas

All ETDs from UAB

The objective of this dissertation was to examine the association between modifiable risk factors and subsequent all-cause and cause-specific late mortality among blood or marrow transplantation (BMT) recipients. I analyzed data for participants who were ≥18 years (y) at study participation from the BMT Survivor Study (BMTSS). BMTSS (U01 CA213140, PI: Bhatia) is a cohort study designed to examine the long-term outcome of individuals who survived ≥2y after undergoing BMT between 1974 and 2014, at the University of Alabama at Birmingham, City of Hope, or University of Minnesota. BMTSS also examines outcomes in an unaffected comparison group drawn from the …

Regulatory Elements Of Polyphosphate Biosynthesis, Marvin Qortez Bowlin

All ETDs from UAB

Polyphosphate (polyP) is an ancient, conserved, inorganic biomolecule. Biological systems have adapted many functions for this high-energy molecule, ranging from immune regulation in mammals to gene regulation in prokaryotes. Of particular interest is its use in bacterial stress responses. Bacteria use polyP to resist hazardous environmental elements like toxic molecules or nutrient starvation. In many bacterial species, polyP is synthesized by polyphosphate kinases (PPKs). PPK – discovered in Escherica coli (E. coli) – hydrolyzes adenosine-5’-triphosphate (ATP) to synthesize polyP. Species that use PPK develop multiple pathogenic defects when PPK activity is impaired, including, among others, antibiotic susceptibility. There is no …

The Influence Of Proximity On Patient Outcomes For Differently Structured Ambulatory Surgery Centers, Wendy Michelle Smith

All ETDs from UAB

THE INFLUENCE OF PROXIMITY ON PATIENT OUTCOMES FOR DIFFERENTLY STRUCTURED AMBULATORY SURGERY CENTERSWENDY SMITH HEALTH SERVICES ADMINISTRATION ABSTRACT This study examines the complication rates and patient-reported outcome measures (PROMs) for total hip and knee replacement surgeries conducted in one of two differently structured ambulatory surgical centers (ASCs) with varying interprofessional surgical teams. There is an ongoing shift from in-hospital total joint replacement surgeries to ASCs. Additionally, there is specialization occurring within ASCs. In this study, we compare single specialty ASCs designed to perform solely TJR surgeries with one orthopedic group and interprofessional team, with multi-specialty ASCs that perform an array …

Prevalence And Phenotype Of Autism Spectrum Disorder Within Pitt Hopkins Syndrome, Helen Kay Root

All ETDs from UAB

Pitt Hopkins Syndrome (PTHS) is an extremely rare genetic disorder which has been described as closely associated with autism spectrum disorder (ASD). While individuals with PTHS have been observed to exhibit symptoms that closely mirror ASD (de Winter et al., 2016; van Balkom et al., 2012; de Pontual et al., 2009; Sweatt, 2013), there have been few studies which have specifically examined ASD-like symptomatology in this population. The current study aims to build understanding regarding the developmental and ASD-specific profile of individuals with PTHS using in-person, observational and elicited standardized assessment measures. Participants included 10 individuals with PTHS aged 2-12 …

Evaluation Of A Hospital Pdmp Ehr-Integration Implementation: A Mixed, Heather D. Martin

All ETDs from UAB

Background: Many providers continue to over prescribe opioids for pain, and Prescription Drug Monitoring Programs (PDMP) can be used as a tool to assist with appropriate opioid prescribing decisions. Despite mandates requiring opioid prescribers to review patients’ prescribing history in their state’s PDMP, barriers to PDMP success still exist such as a difficult PDMP logon process and having to log on to a separate PDMP system, which can cause access, workflow, time commitment, and ease of use issues and deter providers from using the PDMP. Some health care organizations have implemented PDMP electronic health record (EHR) integration (PDMP EHR-integration) to …

Manipulation And Dependence On Host Cell Cycle By Human Rna And Dna Viruses: Human Coronavirus Oc43 And Bk Polyomavirus, Jason M. Needham

All ETDs from UAB

Cell cycle is a universal necessity of cellular life and impacts nearly every process within the cell. However, despite over one hundred years of research, there still remain questions concerning the mechanisms and regulation of eukaryotic cell cycle. From the beginning, viruses have informed our knowledge of cell cycle. Many key regulators such as the E2F transcription factors, Src kinase, and p53 were originally discovered while studying the interactions between viruses and the cell. Herein, we continue the investigation of viral interactions with cell cycle machinery by researching an RNA virus and a DNA virus. These viruses, human coronavirus OC43 …

A Tale Of Two Waves: The Role Of Genomic Enhancers In Regulating Transcriptional And Epigenetic Responses To Neuronal Activitiy, Robert A. Phillips

All ETDs from UAB

The mesolimbic dopamine (DA) pathway, which consists of dopaminergic neurons that project from the ventral tegmental area (VTA) to the nucleus accumbens (NAc), is heavily implicated in drug addiction. Exposure to drugs of abuse results in increases in extracellular concentrations of DA in the NAc, which in turn activates an immediate early gene (IEG) expression program that primarily consists of activity-dependent transcription factors, such as the AP1 subunits Fos and JunB. IEGs engage a set of temporally and functionally distinct genes, termed the late response gene (LRG) expression program. While gene expression changes are critical for drug-dependent adaptations, two major …

Randomized Control Trial Of A Novel Dental Gel As An Adjunct To Scaling And Root Planing In Subjects With Stage Ii & Iii Periodontitis, Sarah Pham

All ETDs from UAB

The current standard of care for treating chronic periodontitis is scaling and root planing (ScRP) followed by supportive periodontal therapy (SPT) (Cobb et al., 2021; Ramfjord et al., 1987). The goal of ScRP is to eliminate supra- and subgingival bacterial deposits and to reduce periodontal pathogens, inflammation, and pocket depths (Greenstein, 2000). Although ScRP has been shown to significantly improve baseline clinical parameters, moderate to advanced cases may require additional surgical therapy which many patients resist (Stambaugh, 1981; Becker et al., 2001). Currently, no dentifrice used adjunctively has been proven to increase the therapeutic effects of scaling and root planing. …

Physical Activity And Related Social Cognitive Theory Constructs By Major Depression Status In Persons With Multiple Sclerosis, Catherine Danielle Jones

All ETDs from UAB

Major depressive disorder (MDD) is highly prevalent among the 1 million per-sons living with multiple sclerosis (MS) in the United States. The prevalence of MDD is nearly 1.7 times higher in persons with MS than in the general population. MDD is associated with negative outcomes in MS, including worse neuropsychological functioning, lower quality of life (QOL), and worse disability. Higher levels of physical activity (PA) are associated with lower depressive symptoms in MS and participation in moderate to vigorous physical activity (MVPA) has been recommended for managing depression se-verity in the general population. However, the rates, patterns, and behavioral correlates …

Secure And Multimodal Personal Safety In Smart Cities With Applications In Interactions And Privacy Preservation For Pedestrians, Raiful Hasan

All ETDs from UAB

The personal safety of pedestrians has increasingly been recognized as a global concern, with a multitude of contributing elements. These include distractions such as smart and wearable device usage, the absence of human-centric systems, infrastructure inadequacies, and traffic regulation. Individuals are increasingly experiencing physical harm as a consequence of reduced attention to their immediate environment, thereby compromising their personal safety. This phenomenon is becoming more prevalent in this fast-paced, technology-driven world, especially among the young. The proliferation of digital devices, such as smartphones and wearable technology, has led to a significant shift in people’s focus from their physical surroundings to …

Suicide Ideation And Risk Factors Among Correctional Officers, Logan Lavender

All ETDs from UAB

The correctional work environment is detrimental to correctional officers’ (COs) health and wellness. While research shows that COs experience high rates of stress, PTSD, and other mental and physical health problems, relatively little research has examined the issue of CO suicide. The current study addresses this knowledge gap by drawing on a survey of COs from Washington state (N=420). Utilizing a Structural Equation Modeling (SEM) framework, this study examines the prevalence of critical incidents (CIs), work stress, PTSD, and suicide ideation, estimates the degree to which exposure to CIs predicts suicide ideation, and assesses how work stress and PTSD moderate …