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Antibacterial And Antibiofilm Effects Of Ziziphus Mauritiana Leaf Extract Against Staphylococcus Aureus, Wiwiek Poedjiastoeti, Irvan Septrian Syah Putra Rasad, Felicia Klarissa Tanzil, Indrayadi Gunardi, Armelia Sari Widyarman

Journal of Dentistry Indonesia

Background: Tooth extraction is a common dental procedure often complicated by postoperative infections, with Staphylococcus aureus as a key opportunistic pathogen. Rising antibiotic resistance and side effects of conventional antiseptics like chlorhexidine highlight the need for natural alternatives. This study evaluated the antibacterial and antibiofilm potential of 96% ethanol extract from Ziziphus mauritiana leaves against S. aureus.

Methods: The extract was prepared by maceration and tested in vitro using microdilution for minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) against S. aureus ATCC 25923. Antibiofilm activity was assessed via crystal violet staining on mature biofilms, with …

Global Research On Palm Oil Diseases And Infections: A Bibliometric Analysis, Fahmi Achmad Saputra, Indria Puti Mustika, Anna Safarida, Catur Sriherwanto, Nicky Rahmana Putra

Makara Journal of Technology

The sustainability of global palm oil production faces significant threats from a range of diseases and infections affecting palm oil crops. This study presents a comprehensive bibliometric analysis to map the scientific landscape and evolution of research related to palm oil diseases over the past decade. Using data from the Scopus database, 366 relevant documents were analyzed using R and VOSviewer to uncover trends in publication volume, citation impact, prolific authors, country contributions, and keyword co-occurrence networks. The findings reveal a strong research concentration on G. boninense, highlighting its critical role as a persistent pathogen in oil palm plantations. Emerging …

Skoring Risiko Mortalitas Pada Pneumonia Komunitas Sedang-Berat, Ni Nyoman Indirawati Kusuma, Gurmeet Singh, Vally Wulani, Cleopas Martin Martin Rumende, Fauzar Fauzar, Telly Kamelia, Sukamto Koesnoe, Adityo Susilo, Hamzah Shatri

Jurnal Penyakit Dalam Indonesia

Introduction. Community Acquired Pneumonia (CAP) is a lung parenchyma infection acquired outside of the hospital and is significantly associated with morbidity and mortality rates. Identifying patients with moderate-severe CAP at high risk of mortality through a combination of these variables is expected to serve as a basis for prompt and appropriate intervention, ultimately improving clinical outcomes for CAP patients. This study aimed to develop a scoring system using clinical characteristics, radiological findings, and serum biomarkers to assess the mortality risk in patients with moderate-severe CAP.

Methods. This study employs a retrospective cohort design with moderate-severe CAP patients treated …

Campak Dan Vaksinasi Campak Pada Orang Dewasa, Robert Sinto, Sukamto Koesnoe, Erni Juwita Nelwan, Alvina Widhani, Sharifah Shakinah, Adeline Pasaribu, Bernadine Gracia Duindrahajeng, Suhendro Suwarto, Leonard Nainggolan, Lie Khie Chen, Adityo Susilo, Suzy Maria, Anshari Saifuddin Hasibuan, Bramantya Wicaksana

Jurnal Penyakit Dalam Indonesia

Measles is a highly contagious viral infection that remains a significant global health problem despite the availability of an effective vaccine. Measles re-emergence is driven by gaps in immunization coverage, waning post-vaccination immunity, and increased population mobility. In adults, measles infection is associated with greater disease severity compared to children. This literature review was conducted by reviewing recent scientific publications addressing the epidemiology, pathogenesis, clinical manifestations, diagnosis, management, complications, and prevention of measles, with a focus on the adult population.  Measles is caused by an RNA virus of the Paramyxoviridae family and is transmitted through respiratory droplets and aerosols. Typical …

Characteristics Of Leprosy Chemoprophylaxis Recipeints In The Tirtayasa Public Health Center Area, 2023–2024, Rifa Imaroh, Maria Angela Lumaksono, Izzah Imani, Dhelya Widasmara

Jurnal Epidemiologi Kesehatan Indonesia

Leprosy remains a public health problem in Indonesia. In 2023, Indonesia ranked third globally in the number of leprosy cases, with 14,376 reported cases, after India (107,851 cases) and Brazil (22,773 cases). One of the key strategies for leprosy control in Indonesia is the implementation of preventive measures, including home visits and the administration of chemoprophylaxis using single-dose rifampicin (SDR). Post-exposure prophylaxis plays an important role in preventing leprosy transmission among contacts of confirmed patients. This study aimed to describe the characteristics of leprosy chemoprophylaxis recipients in the Tirtayasa Public Health Center area during 2023–2024. This study was an descriptive …

Risk Factors Of Leptospirosis Among Agricultural Workers In Southeast Asia: Literature Review, Ronggo Adi Wibowo, Wawa Najwa Nurzakia, Meirany Sasitha Kirana, Yulia Arthemisia Wijaya, Jasmine Ayumaharani Sekaryudha, Dwi Sarwani Sri Rejeki, Rosita Dwi Jayanti

Jurnal Epidemiologi Kesehatan Indonesia

The agricultural sector is the primary source of livelihood for communities in Southeast Asia; however, these activities increase the risk of exposure to zoonotic diseases, particularly leptospirosis. Southeast Asia is one of the regions with the highest incidence of leptospirosis in the world. This literature review aims to identify risk factors for leptospirosis among agricultural workers in Southeast Asia. The search for research articles utilized three databases (Google Scholar, PubMed, and ScienceDirect) using a descriptive approach based on literature review and the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. A total of 9,800 articles were screened for …

Ventilator Weaning Through Spontaneous Breathing Trials In Children With Tetralogy Of Fallot In The Picu: A Case Report, Megah Fitrian, Kadek Ayu Erika, Muhammad Yunus

Jurnal Keperawatan Indonesia

Tetralogy of Fallot (TOF) is a congenital heart defect that causes chronic low oxygen levels, increased right ventricular workload, and a higher risk of complications. Weaning mechanical ventilation in patients with TOF is particularly challenging due to right ventricular dysfunction, muscle weakness, and the risk of heart failure. This study evaluates the use of a spontaneous breathing trial (SBT) strategy with pressure support ventilation (PSV) mode for mechanical ventilation weaning in pediatric patients with TOF. An observational study was conducted on a six-year-old pediatric patient with TOF and a cerebral abscess who underwent mechanical ventilation weaning using the SBT technique …

Impact Of Tropical Cyclones On Food And Nutrition Security: A Global Scoping Review And Thematic Analysis, Patience M. Chiotha, Budi Haryanto

Jurnal Epidemiologi Kesehatan Indonesia

The increasing frequency and intensity of tropical cyclones driven by climate change pose growing threats to food and nutrition security. Globally, an estimated 80–90 tropical cyclones occur annually, affecting approximately 119 million people. Evidence regarding their impact on food systems, dietary patterns, and nutritional status remains fragmented. This scoping review aimed to map global evidence on the impacts of tropical cyclones on food and nutrition security, identify key pathways of impact, and examine affected indicators at household and individual levels. The review followed Joanna Briggs Institute guidelines and PRISMA-ScR. Searches were conducted in PubMed/MEDLINE, Web of Science, Scopus, and Google …

Determinants Of Stunting Among Under-Five Children (0–59 Months) In Central Sulawesi Province, Marchell Bamba, Mondastri Korib Sudaryo, Ratna Djuwita, Helwiah Umniyati

Jurnal Epidemiologi Kesehatan Indonesia

Stunting is caused by chronic malnutrition which can be caused by various factors including poverty, poor nutritional intake and maternal health, and inappropriate infant feeding. This study was conducted to determine what factors cause stunting in Central Sulawesi Province. This study was conducted using a cross-sectional observational analysis method using secondary data from the Survei Kesehatan Indonesia (SKI) 2023. The analysis was carried out using logistic regression. The sample used was 2179 respondents. The dependent variable is stunting while the independent variables are age, gender, area of residence, gestational age, provision of PMT, exclusive breastfeeding, maternal occupation, maternal education, and …

Phytochemistry And Pharmacological Activities Of Sphagneticola Trilobata: A Systematic Review With Perspectives For Drug Discovery, Sonali Dnyaneshwar Labhade, Suraj Kamadi, Pawan Nandkishor Karwa, Ritesh Prakash Bhole, Harshad Sunil Kapare, Sohan Satyanarayan Chitlange

Makara Journal of Science

Sphagneticola trilobata (L.) Pruski is a medicinal plant widely used in traditional medicine for its anti-inflammatory, antimicrobial, antioxidant, hepatoprotective, wound healing, and CNS depressant effects. Despite its broad pharmacolo-gical potential, clinical application is limited due to a lack of mechanistic understanding, standardization, and clinical validation. This review aims to provide a comprehensive overview of the phytochemical composition, pharmacological activities, and therapeutic potential of S. trilobata, while highlighting research gaps and suggesting future directions for clinical translation. A systematic review of scientific literature, ethnobotanical sources, and pharmacological studies was conducted, focusing on phytochemical analysis, biological activity, toxicity, and potential applications …

In Vitro And In Silico Evaluation Of Calcined Chicken Eggshell Powder As An Antibacterial Agent Against Staphylococcus Aureus, Hadi Kurniawan, Hariyanto Ih, Fajar Nugraha, Siti Nani Nurbaeti, Inarah Fajriaty, Ardi Kurniawan, Ridho Maulana Difa

Makara Journal of Science

Staphylococcus aureus is a major Gram-positive pathogen that is increasingly resistant to antibiotics, significantly contributing to antimicrobial resistance (AMR)-related deaths. Therefore, this study aimed to examine the antibacterial activity of calcined chicken eggshell powder (CCEP), a waste-derived material rich in calcium compounds. CCEP was prepared by calcining eggshell powder at 900 °C for 3 hours. Its antibacterial potential was evaluated using in vitro assays, including agar disc diffusion and broth microdilution, as well as in silico molecular docking against penicillin-binding protein 4 (PBP4, PDB ID: 3HUM). The in vitro results showed that a 20% (w/v) CCEP solution in glycerol produced …

Factors Associated With Antiretroviral Therapy Adherence In Patients With Hiv At A Public Hospital In Central Jakarta, Indonesia, Kareena Sari Fatimah, Laily Hanifah, Chandrayani Simanjorang, Nayla Kamilia Fithri

Kesmas

Patients with human immunodeficiency virus (HIV) are required to take antiretroviral therapy (ART) to suppress the virus. However, suboptimal adherence remains a critical barrier that can lead to treatment failure and persistent transmission risks. This study aimed to identify factors associated with ART adherence in patients with HIV. This quantitative study with a cross-sectional design consisted of patients with HIV aged >18 years who received care at the voluntary counseling and testing clinic of a public hospital in Jakarta, Indonesia. Purposive sampling was used. This study used HIV care and ART overview forms as instruments. Data were analyzed using multiple …

Proceeding Book Of The 17th Indonesian Occupational Medicine Updates (Iomu), Perdoki .

Occupational and Environmental Medicine Journal of Indonesia

Bali, Indonesia, 16th - 18th May 2025

Private Sector Healthcare Investment In Indonesia: Leveraging Australia-Indonesia Partnerships For Health System Transformation, Susan Josephine Neuhaus

Journal of Indonesian Health Policy and Administration

Australia and Indonesia are strategic partners with expanding bilateral trade valued at AUD 26.7 billion (2022-23). Health care partnerships between the two countries offer significant opportunities for private sector engagement. Indonesia’s large population, rapidly growing middle class, and implementation of Universal Health Coverage (UHC) through the Jaminan Kesehatan Nasional (JKN) present partnership opportunities to strengthen health system capacity, address infrastructure gaps and workforce shortages, and contribute to shared economic and prosperity goals. This study explores how Australian private healthcare investment can complement government initiatives in supporting Indonesia’s UHC while advancing Australia’s regional engagement. A descriptive qualitative analysis was conducted using …

Analysis Of Coverage Of Tuberculosis Prevention Therapy (Tpt): Literature Review, Septia Rahmalina, Ede Surya Darmawan

Journal of Indonesian Health Policy and Administration

Tuberculosis Preventive Therapy (TPT) is a crucial intervention for tuberculosis (TB) control, particularly among high-risk groups such as household contacts of TB patients and people living with Human Immunodeficiency Virus (HIV). Despite being recommended by the World Health Organization (WHO), TPT implementation still faces challenges at the primary care level. This study employed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) method to review 11 articles published between 2021 and 2025 that were relevant to TPT implementation in various high-TB burden countries, including Indonesia. The main barriers identified were input (logistics, training), process (tracing, education, monitoring), and output …

Prophylactic Antibiotic Analysis In Obs-Gyn, Orthopedics, Gastrointestinal Surgery At A South Tangerang Hospital, January-March 2024, Evelina Endang Nurjaman, Helen Andriani

Journal of Indonesian Health Policy and Administration

Inappropriate use of prophylactic antibiotics (PAs) remains a primary driver of antimicrobial resistance (AMR); however, global adherence to established prescribing guidelines remains suboptimal. This study aimed to analyze the compliance and rationality of PA prescription and to evaluate the underlying causes of physician non-adherence in obstetrics, orthopedic, and gastrointestinal surgeries at a hospital in South Tangerang City, Indonesia. Adopting a mixed-methods approach, this investigation combined a quantitative assessment of 208 surgical patient records (January–March 2024) with qualitative exploratory interviews conducted with three specialist peer group heads. This design allowed the triangulation of prescribing data with underlying clinical perspectives. PA rationality …

The Archaeology Of Alienation: Representation Of Death For The Mentally Illness In Lawang, Malang, Aninda Diandra Rahmadewi, Irmawati Marwoto Imj

International Review of Humanities Studies

Alienation as a novelty in archaeological research which in this study aims to explain how mentally illness patients are buried at Lawang Mental Hospital as an alienation and how the representation of the graves of patients with mentally illness. Alienation is a form of experience by individuals who are marginalized from society, one of which is people with mentally illness. Alienation in mentally illness does not only occur during their lifetime, but continues until they die. Lawang Mental Hospital, built in 1884, is the only mental hospital that has a special cemetery for mentally illness patients. The method used focuses …

Hubungan Faktor Iklim, Faktor Polutan Dan Faktor Sosioekonomi Terhadap Proporsi Pneumonia Balita Provinsi Dki Jakarta Tahun 2013 – 2022, Fayza Chairunnisa Permana, Zakianis Zakianis, Laila Fitria, Erni Pelita Fitratunnisa

Jurnal Nasional Kesehatan Lingkungan Global

In 2022, the Province of DKI Jakarta ranked fourth with the highest coverage of pneumonia in toddlers (53.2%), exceeding Indonesia's toddler pneumonia coverage (38.78%). Pneumonia is influenced by various risk factors, including environmental factors such as climate and weather conditions as well as air pollution, and social and behavioral factors such as toddler characteristics, parental socioeconomic status, and access to health care services. This study aimed to analyze the relationship between climate factors (air temperature, relative humidity, rainfall, and air pressure), pollutant factors (PM₁₀, SO₂, CO, O₃, NO₂), and parents' socioeconomic …

Environmental Health Risks To Children In Sub-Saharan Africa: A Scoping Review Of Evidence And Gaps In Global Interventions, Tadius C. Chitambwe, Dewi Susanna

Jurnal Epidemiologi Kesehatan Indonesia

Sub-Saharan Africa’s (SSA) children experience a disproportionate burden of environmental health risks, contributing to over half of global under-five deaths despite representing only 27% of live births ¹. This scoping review synthesised evidence from sixty-seven (67) eligible studies (2010–2025) to map out environmental exposures affecting children (0–18 years) in Sub-Saharan Africa, and to identify gaps in global interventions. Included studies focused on children (0-18 years) in SSA, addressed one or more of the four predefined environmental exposure domains (air pollution, WASH, toxic chemicals, climate-related risks), and reported on child health outcomes or interventions. Guided by the PRISMA and Arksey …

Kejadian Luar Biasa Gondongan Di Sd Islam X Samarinda, 2024, Rudy Agus Riyanto, Irfansyah Baharuddin Pakki, Mela Sabena, Meli Pasiakan, Erlina Erlina, Rima Andriani

Jurnal Epidemiologi Kesehatan Indonesia

Mumps outbreaks are a public health issue that still frequently occur in elementary school settings, particularly among children with low immunization coverage. Therefore, a comprehensive epidemiological understanding is needed as a basis for control. This research aims to describe the epidemiological picture and causative factors of the mumps outbreak that occurred at Islamic Elementary School X in Samarinda City in 2024, using a case series design. The outbreak occurred from April to October 2024, while epidemiological data collection and case verification were conducted from December 2nd to 8th, 2024. The analysis uses surveillance data, field observations, and questionnaires administered to …

Quantitative Structure-Activity Relationship, Pharmacokinetics, Drug-Likeness, Toxicity, And Molecular Docking Studies Of 4-N-(Methyl)-4-Aminoquinoline Derivatives As Antimalarial Compounds, Muhamad Jalil Baari, Devi Hardiyanti

Makara Journal of Science

Antimalarial drug resistance has encouraged various innovations to develop novel drug compounds that are effective, feasible, and safe, adhering to health standards. One way to do that is by observing and predicting the biological activity of drug compounds using quantitative structure–activity relationship (QSAR) analysis. In this study, QSAR analysis was conducted on the 4-N-(methyl)-4-aminoquinoline derivatives, which effectively inhibit the growth of Plasmodium falciparum as a source of malaria. The research stages involved molecular structure modeling, molecular geometry optimization using the AM1 semi-empirical method, and QSAR descriptor calculations, including electronic (atomic charges (q), HOMO and LUMO energies, polarizability (α), …

The Cytotoxicity And Anti-Inflammatory Properties Of 1’S-1’-Acetoxychavicol Acetate (Aca) On Oral Cells, Nur Umairah Atiqah Sabri, Nor Syazwani Muhammad Zahidan, Zulfahmi Said, Siti Noor Adnalizawati Adnan, Normaliza Ab Malik

Journal of Dentistry Indonesia

Objective: Mouthwash is widely used to maintain oral health by reducing the prevalence of pathogenic microbiomes. Nonetheless, chlorhexidine, a common active ingredient, is associated with side effects including teeth staining, mucosal peeling, mouth and tongue numbness. This has prompted interest in natural alternatives. This study aimed to identify the cytotoxicity and anti-inflammatory properties of 1’S-1’-acetoxychavicol acetate (ACA) isolated from Alpinia conchigera rhizome against human primary gingival fibroblast and keratinocyte (HPGF and HPGK). Methods: Cytotoxicity of ACA (1.57 mg/mL) against HPGF and HPGK was assessed using the MTT assay. Meanwhile, the anti-inflammatory property of ACA was analyzed based on …

Antibacterial Analysis Of Human Amniotic Membrane Against Streptococcus Mutants, Streptococcus Sobrinus, And Enterococcus Faecalis, Mohamad Ezany Yusoff, Ruhil Hayati Hamdan, Haslina Taib, Tan Li Peng, Maizan Mohamed, Rumaizi Shaari, Mohamad Arif Awang Nawi

Journal of Dentistry Indonesia

Objectives: The human amniotic membrane (HAM) is a promising scaffold for oral applications due to its antimicrobial properties, which help protect against bacterial degradation. However, evidence of its activity against oral bacteria remains limited. Thus, this study aimed to evaluate the antibacterial activity of the HAM against selected Gram-positive oral bacteria, namely, Streptococcus mutans (S. mutans), Streptococcus sobrinus (S. sobrinus), and Enterococcus faecalis (E. faecalis). Methods: HAM in 1 cm²-pieces was inoculated with bacterial suspensions and incubated at 37 °C in 5% carbon dioxide (CO₂) for 48 hours to evaluate …

Cost-Benefit Analysis Program Percontohan Pengendalian Rabies Berbasis One Health Di Wilayah Sanur, Denpasar Selatan, Marheni Ni Wayan, Sutarsa I Nyoman, Made Subrata

Jurnal Ekonomi Kesehatan Indonesia

Rabies continues to pose a significant public health challenge in Bali Province, Indonesia. The Dharma Program, a rabies control initiative based on the One Health approach, has been implemented in multiple areas of the province. Sustaining and expanding this program requires an economic evaluation that compares the cost burden of rabies under scenarios with and without program implementation. This study was conducted in two pilot villages: Sanur Kaja (SKJ) and Sanur Kauh (SKH). Cost data were obtained from activity reports, published literature, and structured interviews with program managers. Benefit values were estimated using scenario modeling, which included treatment costs, post-exposure …

Post-Release Health Insurance Utilization Among Ex-Prisoners: A Scoping Review, Icha Khaerunnisa, Megah Andriany, Luky Dwiantoro

Kesmas

The lack of health insurance coverage after prison release significantly reduces access to essential healthcare services, hindering the continuity of care during community reintegration. The evidence on studies of health insurance use following prison release is limited. This scoping review aimed to summarize research on health insurance utilization after release from prison. Literature searches were conducted across databases including ScienceDirect, PubMed, and Scopus. Relevant articles were selected through a two-stage screening process. Data were extracted from the included studies and presented in tabular and descriptive formats. The keywords used were "health insurance AND post-release" and "inmates OR prisoners." This scoping …

Challenges And Policies For Female Sex Workers’ Readiness To Participate In Pre-Exposure Prophylaxis Program: An Explorative Qualitative Study, Rico Januar Sitorus, Anita Rahmiwati, Diana Dewi Sartika, Elvi Sunarsih, Asri Maharani

Kesmas

The prevalence of human immunodeficiency virus is high among female sex workers (FSWs) in Indonesia, underscoring the need for integrated prevention strategies supported by strong government policies. This study aimed to investigate FSWs' willingness to participate in a pre-exposure prophylaxis (PrEP) program. This qualitative study employed semi-structured interviews with 20 participants residing in Pangkal Pinang City, Indonesia (4 stakeholders and 16 FSWs), recruited through purposive sampling. Data were collected from July to September 2024. This non-probability sampling method was adopted due to the focus on specific study objectives and a targeted population. The analysis of the interviews revealed three theme …

Risk Assessment Of Salmonella Spp. Exposure Among Chicken Farm Workers In Phatthalung Province, Southern Thailand, Nutthajit Onmek, Nongyao Mueangdee

Kesmas

This study examined the risk of Salmonella spp. exposure among chicken farm workers by evaluating occupational health management practices. The probability of exposure was determined by assessing the number of contamination points. Sampling for Salmonella spp. contamination was conducted at 7 and 45 days of chicken batches across five areas, alongside evaluation of worker behaviors to assess exposure risk. Three of the 12 large closed-system farms, each housing >10,000 chickens, were selected. Results indicated that boots were the most contaminated items. Workers generally adhered to habitual boot-wearing, which reduced the risk of exposure. Moderate levels of workers' exposure prevention practices, …

Advancing Herbal Medicine: The Role Of Nanosomal Technology In Treating Skin Diseases, Pedro Anugerah Aswan, Baitha Palanggatan Maggadani, Wilzar Fachri, Raditya Iswandana

Pharmaceutical Sciences and Research

Herbal medicine has become popular worldwide, especially in developing countries, with around 80% of the population opting for herbal treatments. The perceived benefits of natural remedies, such as affordability and fewer side effects, drive this trend. Herbal therapies effectively manage skin diseases, infections, and common ailments. However, the absorption of bioactive compounds in herbal extracts is often limited. Recent developments in nano-based herbal delivery systems, like nanosomal, show promise in enhancing the efficacy of herbal remedies for topical applications, providing improved solubility, stability, and skin penetration. This review describes various nanosomal studies developed and successfully used to enhance the topical …

Perceived Benefits And Side Effect Of High-Fiber, High-Protein Meal Replacements In Weight Loss Programs, Esti Nurwanti, Harry Fl Muhammad, Naufal M. Nurdin

Indonesian Journal of Public Health Nutrition (IJPHN)

Obesity is a major risk factor for chronic diseases and early mortality. Although dietary counseling is essential in managing obesity, maintaining a calorie deficit and preventing weight regain remain difficult. Functional foods like high-protein, high-fiber meal replacements may enhance adherence and support weight loss. This randomized controlled trial evaluated the subjective outcomes of a weight loss program incorporating a protein- and fiber-enriched meal replacement among 73 overweight women aged 20–30 years. Participants were randomized to an intervention group (n=38), receiving dietary counseling plus one daily meal replacement, or a control group (n=35), receiving counseling alone. Both groups followed an 8-week …

Simulasi Kenaikan Tarif Cukai Rokok Terhadap Kinerja Ekonomi Rokok Di Indonesia, Diska Agustinningtyas, Neli Agustina

Jurnal Ekonomi dan Pembangunan Indonesia

Production and consumption of cigarettes in Indonesia tend to increase. Increasing production has a positive impact on state revenue. However, the increasing consumption of cigarettes harms public health. The government implemented a policy of cigarette excise tax to control cigarette consumption. This study aims to analyze the impact of increasing the cigarette tax on the economic performance of the cigarette industry. Using Two-Stage Least Squares (2SLS) estimation methods shows that cigarette production is influenced by its consumption. Cigarette consumption is influenced by its price, per capita income in the previous year, and its consumption in the previous year. Cigarette’s price …