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2022 James B. Erdmann Award Recipients

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

Jefferson Center for Interprofessional Practice and Education (JCIPE) congratulates this year’s interprofessional education (IPE) and collaborative practice (CP) award winners and thanks them for all their efforts to support and advance this work on campus and beyond. Their contributions are immeasurable!

Reflections On Jcipe’S Interprofessional Palliative Care Program, Brian Donnelly Bsn

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

JCIPE’s Interprofessional Palliative Care Program is a semester-long learning collaborative in which small interprofessional student teams learn about the team-based provision of palliative care for persons with serious illness and at the end of life. Using the National Consensus Project’s Clinical Practice Guidelines for Quality Palliative Care as a framework, teams work collaboratively through case-based discussions and presentations. Additionally, participants have an opportunity to observe Jefferson’s Palliative Care Team’s interdisciplinary rounds and to shadow a Jefferson palliative care provider.

Curricular Revision And Assessment Of Undergraduate Interprofessional Education, Erin Choice Phd, Cscs, Shelene Thomas Pt, Dpt, Edd, Gcs, Fnap

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

College students who desire a career in the health professions, begin their discovery of professional scope through their undergraduate programs. Currently, there lacks uniformity in undergraduate curricula in knowledge, skills and behaviors necessary for collaborative practice in future healthcare systems (Aldriwesh et al., 2022).

Raising The Bar: Evolution Of A Statewide Interprofessional Education Program Following A 5-Year Outcomes Evaluation, Brittany J. Daulton Phd, Ms, Zachary A. Weber Pharmd, Bcps, Bcacp, Cdces, Fash, April D. Newton Pt, Dpt, Ma, Fnap, Laura Romito Dds, Ms, Mba, Fnap, Barbara Manz Friesth Phd, Rn

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

Indiana University is a complex campus system across the state of Indiana. IU-Bloomington hosts the main campus with nearly 50,000 students, while Indiana University-Purdue University Indianapolis (IUPUI) has approximately 30,000. Additionally, there are seven regional medical school campuses located throughout the state in Gary, Evansville, Fort Wayne, Muncie, South Bend, Terre Haute, and West Lafayette.

Meet An Ipe Student Champion From Thomas Jefferson University, Meredith Gray Ost

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

I had the opportunity to work with two JCIPE programs as a Graduate Assistant – Team Care Planning (TCP) and Enhancing Services for Homeless Populations (ESHP). Team Care Planning involves interprofessional groups of students participating in a simulated discharge planning meeting with a standardized patient. For TCP, I analyzed data from simulation sessions to identify common themes that students discuss when reflecting on their simulation experience. I also worked with the Team Care Planning team to put together materials to market TCP to other universities. Enhancing Services for Homeless Populations is a virtual simulation program utilizing the program Second Life …

Meet An Ipe Faculty Champion From Thomas Jefferson University, Jeannette Kates Phd, Crnp, Agpcnp-Bc, Gnp-Bc

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

I have the privilege of working with JCIPE in several ways. I am currently faculty co-lead for Alzheimer’s Virtual Interprofessional Training (AVIT) and faculty lead for the new Interprofessional Palliative Care Program. Additionally, I have had the opportunity to participate in other JCIPE programs by facilitating for Introductory TeamSAFE and the Health Mentors Program.

Micro-Credentials In Ipe: The Ipe Path Of Distinction And Badger Programs In University Of Wisconsin-Madison, Hossein Khalili Bscn, Mscn, Phd, Fnap, Susan Wenker Pt, Phd, Laura Birkeland Ms, Cgc, Meghan Cotter Phd, Benjamin Weber Ma, Mb, (Ascp)Cm, Julia Schiller Spt, Roberta Rusch Mph

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

The UW CIPE Badger Program is a branch of the UW–Madison Badger program in which we provide focused IPE academic training, called IPE Badges, with fewer academic requirements than a typical degree and/or certificate program. IPE Badges are formal, virtual, micro-credentials issued to learners (students, faculty, staff, or practitioners) who participate in and successfully complete designated IPE offerings and activities at UW–Madison and its partners.

Jcipe Updates

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

JCIPE Updates

From The Editors

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

We’re so excited to share this Spring/ Summer edition of our newsletter! As the academic year comes to a close, we look back on another year filled with ups and downs, incredible accomplishments and ongoing challenges. Life during the COVID-19 pandemic has changed. Relative widespread vaccination and declining mortality and hospitalization rates have allowed a slow return to prior routines and activities for many. Yet infection rates are still on the rise as we continue to mourn the lives lost to COVID in the U.S. and globally, and grapple with its prolonged impact. For many of us, COVID has highlighted …

Collaborative Healthcare: Interprofessional Practice, Education And Evaluation (Jcipe), Volume 12, Number 3, Spring/Summer 2022

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

In this Issue:

• Letter from the Editors
• JCIPE Update
• Micro-Credentials In IPE: The IPE Path of Distinction and Badger Programs in University of Wisconsin-Madison
• Meet an IEP Faculty Champion
• Meet an IPE Student Champion
• Raising the Bar: Evolution of a Statewide Interprofessional Education Program Following a 5-Year Outcomes Evaluation
• Curricular Revision and Assessment of Undergraduate Interprofessional Education
• Reflections on JCIPE's Interprofessional Palliative Care Program
• 2022 James B. Erdmann Award Recipients

Quantification Of Spent Coffee Ground Extracts By Roast And Brew Method, And Their Utility In A Green Synthesis Of Gold And Silver Nanoparticles, Brian G Yust, Niny Z Rao, Evan T Schwarzmann, Madisyn H Peoples

College of Life Sciences Faculty Papers

Nanotechnology has become increasingly important in modern society, and nanoparticles are routinely used in many areas of technology, industry, and commercial products. Many species of nanoparticle (NP) are typically synthesized using toxic or hazardous chemicals, making these methods less environmentally friendly. Consequently, there has been growing interest in green synthesis methods, which avoid unnecessary exposure to toxic chemicals and reduce harmful waste. Synthesis methods which utilize food waste products are particularly attractive because they add value and a secondary use for material which would otherwise be disposed of. Here, we show that spent coffee grounds (SCGs) that have already been …

A Genome-Wide Screen Identifies Pdpk1 As A Target To Enhance The Efficacy Of Mek1/2 Inhibitors, Weijia Cai, Nicole A. Wilski, Timothy J. Purwin, Megane Vernon, Manoela Tiago, Andrew E. Aplin

Department of Cancer Biology Faculty Papers

Melanomas frequently harbor activating NRAS mutations. However, limited advance has been made in developing targeted therapy options for NRAS mutant melanoma patients. MEK inhibitors (MEKi) show modest efficacy in the clinic and their actions need to be optimized. In this study, we performed a genome-wide CRISPR-Cas9-based screen and demonstrated that loss of Phosphoinositide-dependent kinase-1 (PDPK1) enhances the efficacy of MEKi. The synergistic effects of PDPK1 loss and MEKi was validated in NRAS mutant melanoma cell lines using pharmacological and molecular approaches. Combined PDPK1 inhibitors (PDPK1i) with MEKi suppressed NRAS mutant xenograft growth and induced gasdermin E-associated pyroptosis. In an immune-competent …

Grk2 Regulates Adp Signaling In Platelets Via P2y1 And P2y12., Xuefei Zhao, Matthew Cooper, James V Michael, Yanki Yarman, Aiden Baltz, J Kurt Chuprun, Walter J Koch, Steven E. Mckenzie, Maurizio Tomaiuolo, Timothy J Stalker, Li Zhu, Peisong Ma

Department of Medicine Faculty Papers

The critical role of G protein-coupled receptor kinase 2 (GRK2) in regulating cardiac function has been well documented for >3 decades. Targeting GRK2 has therefore been extensively studied as a novel approach to treating cardiovascular disease. However, little is known about its role in hemostasis and thrombosis. We provide here the first evidence that GRK2 limits platelet activation and regulates the hemostatic response to injury. Deletion of GRK2 in mouse platelets causes increased platelet accumulation after laser-induced injury in the cremaster muscle arterioles, shortens tail bleeding time, and enhances thrombosis in adenosine 5'-diphosphate (ADP)-induced pulmonary thromboembolism and in FeCl3-induced carotid …

The Hearst Health Prize: The First Five Years, Alexa M. Waters, Alexis Skoufalos, Emily Frelick, Gregory Dorn, David B. Nash

Department of Family & Community Medicine Faculty Papers

The Hearst Health Prize is the first national annual award for excellence in population health. The prize was established "to discover, support, and showcase the work of an individual, group, organization, or institution that has successfully implemented a population health program or intervention that has made a measurable difference" in health outcomes. Now, 5 years since the award's inception, this article reflects on how submissions for the prize collectively mirror - and may even predict - changes within the field of population health. It examines how the most successful programs demonstrated genuine, measurable improvements in health outcomes and/or health behaviors. …

A Qualitative Exploration Of The Functional, Social, And Emotional Impacts Of The Covid-19 Pandemic On People Who Use Drugs, Erin L Kelly, Megan K Reed, Kathryn M Schoenauer, Kelsey Smith, Kristina Scalia-Jackson, Sequoia Kay Hill, Erica Li, Lara Weinstein

Department of Family & Community Medicine Faculty Papers

Since 2020, people who use drugs (PWUD) experienced heightened risks related to drug supply disruptions, contamination, overdose, social isolation, and increased stress. This study explored how the lives of PWUD changed in Philadelphia over a one-year period. Using semi-structured interviews with 20 participants in a Housing First, low-barrier medication for opioid use (MOUD) program in Philadelphia, the effects of the first year of the COVID-19 pandemic on the daily lives, resources, functioning, substance use, and treatment of PWUD were explored. Interviews were analyzed using a combination of directed and conventional content analysis. Six overarching themes emerged during data analysis: (1) …

Implementation And Outcomes Of A Remote Hepatitis B Screening Program Designed To Overcome Covid-19 Pandemic-Related Disruptions To Community-Based Screenings For Asians In Greater Philadelphia: A Descriptive Study, Yoonhee P Ha, Yusha Sun, Jack Wilkinson, Sonia Wang, Lillian Chien, Marisa Wu, Evangeline Wang, Catherine Freeland

College of Population Health Faculty Papers

No abstract provided.

Feasibility Of The Transport Plus Intervention To Improve The Transitions Of Care For Patients Transported Home By Ambulance: A Non-Randomized Pilot Study, Kevin G Munjal, Sai Kaushik Yeturu, Hugh H Chapin, Nadir Tan, Diana Gregoriou, Daniela Garcia, Corita Grudzen, Ula Hwang, Barbara Morano, Hayley Neher, Ksenia Gorbenko, Glen Youngblood, Anjali Misra, Staley Dietrich, Cyndi Gonzalez, Giselle Appel, Erica Jacobs, Albert Siu, Lynne D Richardson

Student Papers, Posters & Projects

BACKGROUND: The growing population of patients over the age of 65 faces particular vulnerability following discharge after hospitalization or an emergency room visit. Specific areas of concern include a high risk for falls and poor comprehension of discharge instructions. Emergency medical technicians (EMTs), who frequently transport these patients home from the hospital, are uniquely positioned to aid in mitigating transition of care risks and are both trained and utilized to do so using the Transport PLUS intervention.

METHODS: Existing literature and focus groups of various stakeholders were utilized to develop two checklists: the fall safety assessment (FSA) and the discharge …

News In Brief

Jefferson Surgical Solutions

Francesco Palazzo, MD, has been promoted to Professor of Surgery.

Drs. Adam Bodzin, George Koenig, and Dawn Salvatore, have been promoted to Associate Professor of Surgery.

T. Sloane Guy, MD, MBA, was recently appointed Vice Chief of the Division of Cardiac Surgery and Clinical Director, Cardiac Surgery at Thomas Jefferson University Hospital.

Chair of Surgery at Jefferson Health – Abington, Orlando Kirton, MD, was named a 2022 History Maker by the Philadelphia Tribune.

General Surgery resident, Sunjay Kumar, MD, was named the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) Guidelines Fellow for …

Full Issue: Volume 17, Number 1 - Summer 2022

Jefferson Surgical Solutions

A publication for friends and colleagues of Jefferson’s Department of Surgery

In This Issue

Cover Story
Jefferson Aortic Center Targets ‘Silent Killers’ with Individualized Care, Innovative Research - Page 1

Overview
Finally -- A Measure of Normalcy - Page 2

Please Welcome
New Faculty - Page 2

Research
Pancreatic Researchers Advance Next-Generation Molecular Profiling - Page 2

On the Job
Meet the Staff - Page 3

Education
Residency Program Receives Five-Year Accreditation, Reorganizes to Serve Growing Program - Page 3

Those Who Give
Naming Opportunities at New Jefferson Specialty Care Pavilion - Page 4

News in Brief
News in Brief …

Residency Program Receives Five-Year Accreditation, Reorganizes To Serve Growing Program

Jefferson Surgical Solutions

The General Surgery Residency Program within the Department of Surgery received full accreditation for five years from the Accreditation Council for Graduate Medical Education (ACGME) in January 2022. In March, the Residency Program completed a successful match—selecting seven categorical residents from about 1,600 applications. And in June, it said goodbye to longtime Residency Program Administrator Donna Guinto, who retired after 38 years with Jefferson.

Since Guinto became coordinator in 1994, the Department of Surgery’s Residency Program has grown in length (from five to six years), number of residents (from six to seven) and complexity (with more guidelines from ACGME and …

Naming Opportunities At New Jefferson Specialty Care Pavilion

Jefferson Surgical Solutions

The Specialty Care Pavilion represents the most significant new patient care facility at Jefferson since the 1970s. With a total cost of more than $762 million, it will serve as a model for modern medical facilities and a cornerstone of Jefferson’s Center City, Philadelphia campus.

On schedule to open to patients in spring 2024, the 19-story building will consolidate more than ten different specialties – including surgery – in 460,000 square feet at 1101 Chestnut Street. It will feature emerging technologies to support an intelligent, responsive approach to care, as well as a seamless in-person and virtual experience for patients. …

New Faculty

Jefferson Surgical Solutions

We are pleased to announce the recent appointment of Anthony Macchiavelli, MD, as Assistant Professor in the Division of Vascular Medicine.

In 1983, Dr. Macchiavelli received his BS in Physics from the United States Military Academy in West Point, NY, and subsequently served as a United States Army Officer from May 1983 – July 1986. He then received his MD from the Lewis Katz School of Medicine at Temple University in 1996 and remained in Philadelphia to complete his residency in Medicine (1996-1998) at Graduate Hospital. From 1998 to present, Dr. Macchiavelli has worked in Internal and Hospital Medicine in …

Pancreatic Researchers Advance Next-Generation Molecular Profiling

Jefferson Surgical Solutions

The Jefferson Pancreas, Biliary and Related Cancer Center performs more pancreas surgeries than any other center in the tristate region. Each year, the center’s team treats more than 200 patients who have cancerous, neoplastic or pre-cancerous lesions.

It’s a level of care and volume of patients that presents a powerful opportunity: using molecular profiling to gather extensive data about pancreatic tumors. Molecular profiling can be a valuable tool in treating pancreatic cancer – now the third-leading cause of cancer-related deaths with a five-year overall survival rate of just 11%.

“With molecular profiling, we’re looking for patterns and signatures within the …

Meet The Staff

Jefferson Surgical Solutions

This Spring, Paul Hazen and Brielle Maugeri joined the Department of Surgery as Education Programs Administrator and Residency Program Coordinator, respectively. In these roles, Hazen and Maugeri will support expansion of the Department of Surgery’s Graduate Medical Education (GME) programs.

Paul Hazen

Hazen joined Jefferson from Einstein Health, where he was a residency coordinator and then a fellowship coordinator. Prior to that, he served as program manager for Emergency Medicine at Drexel Hahnemann and held administrative roles at Georgetown University in Washington, DC.

At Jefferson, Hazen is focusing on centralizing the Department of Surgery’s educational programs and streamlining and standardizing …

Development Of The Centrifugal Blood Pump For A Hybrid Continuous Flow Pediatric Total Artificial Heart: Model, Make, Measure, Carson S Fox, Thomas Palazzolo, Matthew Hirschhorn, Randy M Stevens, Joseph Rossano, Steven W Day, Vakhtang Tchantchaleishvili, Amy L Throckmorton

Department of Medicine Faculty Papers

Clinically-available blood pumps and total artificial hearts for pediatric patients continue to lag well behind those developed for adults. We are developing a hybrid, continuous-flow, magnetically levitated, pediatric total artificial heart (TAH). The hybrid TAH design integrates both an axial and centrifugal blood pump within a single, compact housing. The centrifugal pump rotates around the separate axial pump domain, and both impellers rotate around a common central axis. Here, we concentrate our development effort on the centrifugal blood pump by performing computational fluid dynamics (CFD) analysis of the blood flow through the pump. We also conducted transient CFD analyses (quasi-steady …

A Systematic Review Of Reproductive Counseling In Cases Of Parental Constitutional Reciprocal Translocation (9;22) Mimicking Bcr-Abl1, Zimeng Gao, Stephanie M Rice, Sascha Wodoslawsky, Sara C Long, Zi-Xuan Wang, Mehnoosh Torkzaban, Ana Milena Angarita Africano, Jinglan Liu, Huda B Al-Kouatly

Department of Obstetrics and Gynecology Faculty Papers

We aim to determine the spectrum of cytogenetic abnormalities and outcomes in unbalanced offspring of asymptomatic constitutional balanced t(9;22) carriers through a systematic literature review. We also include a case of a constitutional balanced t(9;22) carrier from our institution. Among the 16 balanced t(9;22) carriers in our review, 13 were maternal and 3 were paternal. Of the 15 unbalanced translocation cases identified, 13 were live births, one was a missed abortion, and one resulted in pregnancy termination. The spectrum of established syndromes reported among the live births was the following: trisomy 9p syndrome (6/13), dual trisomy 9p and DiGeorge syndrome …

Impact Of The Time To Surgery On Visual Outcomes For Rhegmatogenous Retinal Detachment Repair: A Meta-Analysis, Amirthan Sothivannan, Arshia Eshtiaghi, Arjan S. Dhoot, Marko M. Popovic, Sunir J. Garg, Peter J. Kertes, Rajeev H. Muni

Wills Eye Hospital Papers

PURPOSE: To determine the relationship between time from symptom onset or presentation to repair and visual outcomes for macula-on and macula-off rhegmatogenous retinal detachment (RRD).

DESIGN: Meta-analysis.

METHODS: We searched MEDLINE, EMBASE, and Cochrane Library for randomized controlled trials and observational studies comparing best-corrected visual acuity (BCVA) based on time to RRD repair. Study identifiers, baseline characteristics, intervention characteristics, and visual outcomes were extracted. We conducted a random effects meta-analysis. Sensitivity analyses included leave-1-out and influence analyses. Primary outcomes included mean difference (MD) in final BCVA, MD between preoperative and final BCVA (∆BCVA), and relative risk of final BCVA24 hours. …

Finally -- A Measure Of Normalcy, Charles Yeo, Md, Facs

Jefferson Surgical Solutions

After two very abnormal years of celebrations, our Department of Surgery Annual Banquet returned in fine style this past June 17. The venue was spectacular – The Franklin Institute. This black tie event was much anticipated, and did not disappoint. Finally – a measure of normalcy.

We gathered for cocktails, shared a meal and were treated to amazing presentations from our outgoing Chief Residents: Drs. Alvarez, Devin, O’Malley, Rios Diaz, Woodward, Zalewski, and Zheng. The statue of Ben Franklin, standing tall at the center of the room, served as a magnet for photos – and proved to be an imposing …

Jefferson Aortic Center Targets ‘Silent Killers’ With Individualized Care, Innovative Research

Jefferson Surgical Solutions

Jacqueline McGee, CRNP, and Konstadinos Plestis, MD, in the shared reception area for the Aortic Center, Angioplasty Center, and Vascular Center at 111 S. 11th Street in Center

The experience of 79-year-old Jane Collins illustrates the unique challenges of diagnosing and treating aortic disease. Her experience also demonstrates the value of the Jefferson Aortic Center – one of only a few in the nation to provide this complex care at a high volume.

Like an estimated 95% of people with aortic disease, Collins had no symptoms, and her diagnosis was incidental. An X-ray to explore back pain revealed that she …

Outcomes Following Abiraterone Versus Enzalutamide For Prostate Cancer: A Scoping Review, Yash B, Shah, Amy L. Shaver, Jacob Beiriger, Sagar Mehta, Nikita Nikita, William Kevin Kelly, Stephen J. Freedland, Grace Lu-Yao

Department of Medical Oncology Faculty Papers

Abiraterone acetate (AA) and enzalutamide (ENZ) are commonly used for metastatic prostate cancer. It is unclear how their outcomes and toxicities vary with patient-specific factors because clinical trials typically exclude patients with significant comorbidities. This study aims to fill this knowledge gap and facilitate informed treatment decision making. A registered protocol utilizing PRISMA scoping review methodology was utilized to identify real-world studies. Of 433 non-duplicated publications, 23 were selected by three independent reviewers. ENZ offered a faster and more frequent biochemical response (30-50% vs. 70-75%), slowed progression (HR 0.66; 95% CI 0.50-0.88), and improved overall survival versus AA. ENZ was …