Digital Commons Network^™

Ic 042 Gude To Texas Children's Hospital Historical Archives, 1953-2003, Texas Children's Hospital

Institutional Finding Aids

Texas Children's Hospital Historical Archives contains 10 cubic feet of processed material and 79 boxes of unprocessed material. The later is labeled as the TCH Historical Archives and arrived in the HRC in 2008. See more at IC 042.

Ic 041 Gude To Women's Auxiliary To Texas Children's Hospital Records, 1954-2014, Women's Auxiliary To Texas Children's Hospital

Institutional Finding Aids

The collection contains photographs, audiovisual materials, meeting minutes, meeting notes, organizational handbooks, publications, and scrapbooks. The collection includes 83 scrapbooks that date from 1954 to 2014. See more at IC 041.

Ic 037 Guide To Hgac - Agency (Houston Galveston Area Council) Records, 1975-1980, Houston-Galveston Area Council

Institutional Finding Aids

The HGAC Agency collection contains applications for Hermann Hospital, St. Luke’s, TCH, THI, Gulf Coast dialysis Center, Methodist, VA Hospital, West Houston Dialysis Center, UT System Cancer Center, and Zimmerman Medical Clinic Dialysis Center. The collection also contains annual reports, general information, spectrum, health service plan, health system plan draft, project review report, copies of the Health Times, newsletters, directory (water damaged), the Area Agency on Aging bulletin, and other related prints. See more at IC 037.

Ic 036 Guide To South Central Chapter Of The Medical Library Association Records, 1966-2018, Medical Library Association. South Central Regional Group

Institutional Finding Aids

The South Central Chapter of the Medical Library Association records (SCC/MLA) contain organizational history, photographs, bylaws, reports, policies, annual meeting records, executive board records, meeting minutes, committee documents, local arrangements materials, membership directories, procedure manuals, newsletters, oral histories, and digital media. The collection documents the activities, people, membership, leaders, and committee work of the SCC/MLA, a professional organization of medical librarians and libraries. See more at IC 036.

Ic 034 Guide To San Jacinto Lung Association Records, 1895-1993, San Jacinto Lung Association

Institutional Finding Aids

The San Jacinto Lung Association records include correspondence, legal documents, budgets, tuberculosis statistics, committee reports and minutes, printed materials, scrapbooks, articles, christmas seals, and photographs that document the history, community services, staff and administration of the San Jacinto Lung Association. See more at IC 034.

Ic 031 Gude To Doctors' Club Records, 1954-2005, The Doctors' Club

Institutional Finding Aids

The Doctor's Club records (IC 031) is 8 cubic feet and consists of 2 documents boxes and 2 oversize boxes and 14 artifacts. It contains a club profile, brochures, correspondence, programs and newsletters (Memos) from the years 1954 to 2002. See more at IC 031.

Ic 030 Guide To Harris County Health Department Records, 1955-2008, Harris County Health Department

Institutional Finding Aids

The Harris County Health Department collection contains a disease control update, communicable disease report, news and views, epidemiology notes, Harris County Hospital District newsletter, annual reports, and ethnic distribution of census population report. See more at IC 030.

Ic 025 Gude To University Of Texas School Of Nursing Records, 1978-2006, University Of Texas Health Science Center At Houston. School Of Nursing

Institutional Finding Aids

This collection consists of records including catalogs, brochures, annual report, six-year plan, 1979 roster, and information memorandum from the University of Texas, School of Nursing The materials were created between 1978-2006. See more at IC 025.

Ic 022 Guide To Hermann Hospital Records, 1907-1997, Memorial Hospital System

Institutional Finding Aids

The Memorial Hospital System records (IC 022) contains photographs, scrapbooks, M news, Memorial Foundation News in Partnership, Margaret Ophelia Neal trust, WWI photo album, student nurses hospital scenes, Caducean (some water damage to paper), publications, telephone directory, news clippings, press releases, histories, hospital rules, donors, catalogs, handbooks, poster of “This Magic Moment”, and other papers and printed materials. See more at IC 022.

Ic 021 Guide To St. Luke's Episcopal Hospital Records, 1959-2011, St. Luke's Episcopal Hospital (Houston, Tx)

Institutional Finding Aids

St. Luke’s Episcopal Hospital, now known as Baylor St Luke’s Medical Center in CHI St. Luke’s Health Center was established in 1962 by Denton A Cooley. The materials are generally in good condition. The collection contains newsletters, directories and rosters, bylaws, brochures, and 6mm films. See more at IC 021.

Ic 020 Guide To Methodist Hospital Records, 1925-1996, Methodist Hospital (Houston, Tx)

Institutional Finding Aids

The Methodist Hospital records contains materials from the Methodist Hospital and the Bluebird Circle covering the years from the 1940s into the 1990s. The materials are generally in good condition. Materials include newsletters, news clippings, minutes, press releases, article drafts, scrapbooks, general historical information, photographs, sound recordings, and brochures. The Methodist Hospital History Project is included in this collection but was donated complete and has its own inventory. See more at IC 020.

Ic 019 Guide To Hermann Hospital Records, 1949-1993, Hermann Hospital (Houston, Tex.)

Institutional Finding Aids

The collection contains records from the George Hermann estate and from Hermann Hospital covering the years from circa 1900 to 2004. The condition of the materials range from endangered to good condition. Materials include correspondence, ledgers, memos, photographs, 35 mm slides, realia, and ephemera. See more at IC 019.

Ic 018 Gude To Harris County Hospital District Records, 1919-1977, Harris County Hospital District

Institutional Finding Aids

The Harris County Hospital District collection primarily consists of patient records, emergency room logbooks, tuberculosis logbooks, hospital operations logbooks, and baby logbooks. The collection also includes copies of The Beat and Progress newsletters, annual reports, records, telephone directories, employee handbooks, budget information, an eligibility procedure manual, and other printed material. See more at IC 018.

Ic 017 Guide To The Institute For Rehabilitation And Research, Tirr Records, 1950-1996, Institute For Rehabilitation And Research (Houston, Tex.)

Institutional Finding Aids

The Institute for Rehabilitation and Research collection contains slides, Department of rehabilitation annual reports, The Spinal Connection, TIRR year in review, Midweek newsletter, Connection newsletter, TIRR annual report, Southwestern Poliomyelitis Respiratory Center Administrative reports, Scoliosis Paul R. Harrington, issues of Promethean, Rehabilitation Research and Training Center reports, and other related printed materials. See more at IC 017.

Ic 016 Guide To Institute Of Religion Records, 1954-2000, Institute Of Religion (Houston, Tx)

Institutional Finding Aids

The Institute of Religion records is .5 cubic foot and consists of 1 document box. It contains formation and scope documents, newsletters, correspondence, pamphlets and news clippings related to the early years of the Institue of Religion, now the Institute of Spirituality and Health. The materials are in good condition. See more at IC 016.

Ic 015 Guide To Texas Research Institute Of Mental Sciences (Trims) Records, 1957-1985, Texas Research Institute Of Mental Sciences

Institutional Finding Aids

The TRIMs collection contains annual reports, annual financial reports, audit reports, highlights, news clippings and articles, constitution, bylaws, rules and regulations, dedication, publicity, linkages, correspondence, administration, organization of clinical services and committees, library information, audio visual, public information, communications, volunteer services, donations, program change proposals and approvals, evaluations, research advisory council, medical advisory committee, commissioners annual review, legislature visit to medical center, statistical information, comprehensive health planning, medical records, contracts, agreements, memos, manuals, salary increases, equal employment opportunity information and complaints, active medical staff, personnel, incidents, grievances, client abuse reports, travel reports, construction projects, minutes, reports of grants and donations, …

Ic 014 Guide To University Of Texas M.D. Anderson Cancer Center Records, 1946-2000, University Of Texas M.D. Anderson Cancer Center

Institutional Finding Aids

The UT MD Anderson Cancer Center records contains newsletters, articles on Neoplasia, annual reports, staff directories, publications, nursing neogram, research protocols, statistics, committee reports, Dr. Clark’s retirement comments, policies, employee handbooks, clinical training grants, internal reviews, printed materials, academic plans, research reports, and Christmas card project dating from 1946-2000. See more at IC 014.

Ms 215 Guide To The Boris Yoffe, Md Papers, 1990s-2000s, Boris Yoffe

Manuscript Finding Aids

Boris Yoffe, MD papers contains photographic prints and 35mm slides related to Radiation Effects and Events. They document the trips to Eastern Europe with Dr. Armin Weinberg. Other materials in the collection include: 7 books, 2 VHS cassette tapes, a Rotary Cell Culture System with 3 rotary culture vessels, and slides related to the rotary cell culture system and liver experiments. See more at MS 215.

Ms225: 2019 Faculty Meeting Minutes, Thomas R. Cole

Thomas R. Cole, PhD Papers

Original Filename: Faculty Meeting Minutes 011619.docx. Format Details: fmt/412; Microsoft Word for Windows; 2007 onwards. See more at Thomas R. Cole, PhD Papers and its finding aid.

Resting-State Functional Connectivity Of The Habenula In Mood Disorder Patients With And Without Suicide-Related Behaviors, Elisa Ambrosi, David B Arciniegas, Kaylah N Curtis, Michelle A Patriquin, Gianfranco Spalletta, Gabriele Sani, B Christopher Frueh, J Christopher Fowler, Alok Madan, Ramiro Salas

Staff and Researcher Publications

The habenula is a small midbrain structure that is important for brain signaling and learning from negative events. Thus, the habenula is strongly connected to both the reward system and motor regions. Increasing evidence suggests a role for the habenula in the etiology of psychiatric disorders, including mood and substance use disorders. However, no studies to date have investigated habenular resting-state functional connectivity (rsFC) in suicide-related behaviors (SB). The authors enrolled 123 individuals with major depressive disorder (MDD) or bipolar disorder and a history of suicide-related behaviors (SB+), 74 individuals with MDD or bipolar disorder and a history of suicidal …

Disruption Of Immune Homeostasis In Human Dendritic Cells Via Regulation Of Autophagy And Apoptosis By Porphyromonas Gingivalis, Mohamed M Meghil, Omnia K Tawfik, Mahmoud Elashiry, Mythilypriya Rajendran, Roger M Arce, David J Fulton, Patricia V Schoenlein, Christopher W Cutler

Faculty, Staff and Student Publications

As fundamental processes of immune homeostasis, autophagy, and apoptosis must be maintained to mitigate risk of chronic inflammation and autoimmune diseases. Periodontitis is a chronic inflammatory disease characterized by oral microbial dysbiosis, and dysregulation of dendritic cell (DC) and T cell responses. The aim of this study was to elucidate the underlying mechanisms by which the oral microbe

Gwas Of Qrs Duration Identifies New Loci Specific To Hispanic/Latino Populations, Brenton R Swenson, Tin Louie, Henry J Lin, Raúl Méndez-Giráldez, Jennifer E Below, Cathy C Laurie, Kathleen F Kerr, Heather Highland, Timothy A Thornton, Kelli K Ryckman, Charles Kooperberg, Elsayed Z Soliman, Amanda A Seyerle, Xiuqing Guo, Kent D Taylor, Jie Yao, Susan R Heckbert, Dawood Darbar, Lauren E Petty, Barbara Mcknight, Susan Cheng, Natalie A Bello, Eric A Whitsel, Craig L Hanis, Mike A Nalls, Daniel S Evans, Jerome I Rotter, Tamar Sofer, Christy L Avery, Nona Sotoodehnia

Faculty, Staff and Student Publications

BACKGROUND: The electrocardiographically quantified QRS duration measures ventricular depolarization and conduction. QRS prolongation has been associated with poor heart failure prognosis and cardiovascular mortality, including sudden death. While previous genome-wide association studies (GWAS) have identified 32 QRS SNPs across 26 loci among European, African, and Asian-descent populations, the genetics of QRS among Hispanics/Latinos has not been previously explored.

METHODS: We performed a GWAS of QRS duration among Hispanic/Latino ancestry populations (n = 15,124) from four studies using 1000 Genomes imputed genotype data (adjusted for age, sex, global ancestry, clinical and study-specific covariates). Study-specific results were combined using fixed-effects, inverse variance-weighted …

Free Water In White Matter Differentiates Mci And Ad From Control Subjects, Matthieu Dumont, Maggie Roy, Pierre-Marc Jodoin, Felix C Morency, Jean-Christophe Houde, Zhiyong Xie, Cici Bauer, Tarek A Samad, Koene R A Van Dijk, James A Goodman, Maxime Descoteaux

Faculty, Staff and Student Publications

Recent evidence shows that neuroinflammation plays a role in many neurological diseases including mild cognitive impairment (MCI) and Alzheimer's disease (AD), and that free water (FW) modeling from clinically acquired diffusion MRI (DTI-like acquisitions) can be sensitive to this phenomenon. This FW index measures the fraction of the diffusion signal explained by isotropically unconstrained water, as estimated from a bi-tensor model. In this study, we developed a simple but powerful whole-brain FW measure designed for easy translation to clinical settings and potential use as a priori outcome measure in clinical trials. These simple FW measures use a "safe" white matter …

Multistate Outbreaks Of Foodborne Illness In The United States Associated With Fresh Produce From 2010 To 2017, Christina K Carstens, Joelle K Salazar, Charles Darkoh

Faculty, Staff and Student Publications

In the United States, the consumption of fresh fruits and vegetables has increased during recent years as consumers seek to make healthier lifestyle choices. However, the number of outbreaks associated with fresh produce that involve cases in more than one state (multistate) has increased concomitantly. As the distance along the farm-to-fork continuum has lengthened over time, there are also more opportunities for fresh produce contamination with bacterial pathogens before it reaches the consumer. This review provides an overview of the three bacterial pathogens (i.e., pathogenic

The Role Of Botulinum Toxin Type-A In Spasticity: Research Trends From A Bibliometric Analysis, Christine A Liang, Jing Liu, Jaiyeola Thomas Ogunniyi, Hui Zhu, Songlin Zhang

Faculty, Staff and Student Publications

AIMS: Since the six-tier Milan salivary gland classification has been introduced, there are very limited studies in literature reporting the risk stratification of the Milan classification.

METHODS: We retrospectively classified a total of 285 salivary gland cytology cases into Milan reporting categories; there were 23 (8.1%) nondiagnostic, 48 (16.8%) nonneoplastic, 19 (6.7%) atypia of undetermined significance (AUS), 138 (48.4%) benign neoplasm, 13 (4.6%) neoplasm of uncertain malignant potential (NUMP), 8 (2.8%) suspicious for malignancy, and 36 (12.6%) malignant. Almost 110 cases (38.6%) had surgical follow-up resections.

RESULTS: The overall risk for malignancy (ROM) was 12.5% for AUS, 3.2% for benign …

Mesenchymal Stromal Cell Therapeutic Delivery: Translational Challenges To Clinical Application, Henry Caplan, Scott D Olson, Akshita Kumar, Mitchell George, Karthik S Prabhakara, Pamela Wenzel, Supinder Bedi, Naama E Toledano-Furman, Fabio Triolo, Julian Kamhieh-Milz, Guido Moll, Charles S Cox

Faculty, Staff and Student Publications

For several decades, multipotent mesenchymal stromal cells (MSCs) have been extensively studied for their therapeutic potential across a wide range of diseases. In the preclinical setting, MSCs demonstrate consistent ability to promote tissue healing, down-regulate excessive inflammation and improve outcomes in animal models. Several proposed mechanisms of action have been posited and demonstrated across an array of in vitro models. However, translation into clinical practice has proven considerably more difficult. A number of prominent well-funded late-phase clinical trials have failed, thus calling out for new efforts to optimize product delivery in the clinical setting. In this review, we discuss novel …

A Proof-Of-Mechanism Study To Test Effects Of The Nmda Receptor Antagonist Lanicemine On Behavioral Sensitization In Individuals With Symptoms Of Ptsd, Marijn Lijffijt, Charles E Green, Nicholas Balderston, Tabish Iqbal, Megan Atkinson, Brittany Vo-Le, Bylinda Vo-Le, Brittany O'Brien, Christian Grillon, Alan C Swann, Sanjay J Mathew

Faculty, Staff and Students Publications

Background: Individuals with post-traumatic stress disorder (PTSD) have a heightened sensitivity to subsequent stressors, addictive drugs, and symptom recurrence, a form of behavioral sensitization. N-methyl-D-aspartate receptors (NMDARs) are involved in the establishment and activation of sensitized behavior.

Objective: We describe a protocol of a randomized placebo-controlled Phase 1b proof-of-mechanism trial to examine target engagement, safety, tolerability, and possible efficacy of the NMDAR antagonist lanicemine in individuals with symptoms of PTSD (Clinician Administered PTSD Scale [CAPS-5] score ≥ 25) and evidence of behavioral sensitization measured as enhanced anxiety-potentiated startle (APS; T-score ≥ 2.8).

Methods: Subjects (n = 24; age range 21–65) …

Deep Patient Representation Of Clinical Notes Via Multi-Task Learning For Mortality Prediction, Yuqi Si, Kirk Roberts

Faculty, Staff and Student Publications

We propose a deep learning-based multi-task learning (MTL) architecture focusing on patient mortality predictions from clinical notes. The MTL framework enables the model to learn a patient representation that generalizes to a variety of clinical prediction tasks. Moreover, we demonstrate how MTL enables small but consistent gains on a single classification task (e.g., in-hospital mortality prediction) simply by incorporating related tasks (e.g., 30-day and 1-year mortality prediction) into the MTL framework. To accomplish this, we utilize a multi-level Convolutional Neural Network (CNN) associated with a MTL loss component. The model is evaluated with 3, 5, and 20 tasks and is …

Melatonin Enhances Sorafenib-Induced Cytotoxicity In Flt3-Itd Acute Myeloid Leukemia Cells By Redox Modification, Tian Tian, Jiajun Li, Yizhuo Li, Yun-Xin Lu, Yan-Lai Tang, Hua Wang, Fufu Zheng, Dingbo Shi, Qian Long, Miao Chen, Guillermo Garcia-Manero, Yumin Hu, Lijun Qin, Wuguo Deng

Faculty, Staff and Student Publications

Acute myeloid leukemia (AML) with an internal tandem duplication in Fms-related tyrosine kinase 3 (FLT3-ITD) is identified as a subgroup with poor outcome and intrinsic resistance to chemotherapy and therefore urgent need for development of novel therapeutic strategies.

Methods: The antitumor effects of melatonin alone or combined with sorafenib were evaluated via flow cytometry and immunoblotting assays in FLT-ITD AML cells. Also, the ex vivo and in vivo models were used to test the synergistic effects of melatonin and sorafenib against leukemia with FLT3/ITD mutation.

Results: Our study shows for the first time that melatonin inhibits proliferation and induces apoptosis …

Impact Of Technology On Improving Hiv And Tuberculosis Health Outcomes Among African Countries, Sunny Ibeneme

Dissertations and Theses (Open Access)

This study used health analytics approach to evaluate the association between population health outcomes and Information and Communication Technology (ICT) infrastructures at a country level. This study used aggregate data obtained from the World Bank database, and the International Telecommunication Union (ITU) database for 53 African countries for the periods 2000 to 2016, and quantitatively explored the impact of ICT infrastructures’ diffusion on population health outcomes.

ICT data was obtained from the ITU database. Similarly, population health attributes were retrieved from the World Bank database. ICT infrastructure variables used in this study include: internet access, mobile phone use, and fixed …