Digital Commons Network^™

The Role Of Type I Insulin-Like Growth Factor Receptor Signaling In Breast Cancer Brain Metastasis, Sandra M. Saldana

Dissertations and Theses (Open Access)

Brain metastasis is a common cause of mortality in cancer patients. Approximately 20-30% of breast cancer patients acquire brain metastasis, yet potential therapeutic targets remain largely unknown. The type I insulin-like growth factor receptor (IGF- IR) is known to play a role in the progression of breast cancer and is currently being investigated in the clinical setting for various types of cancer. The present study demonstrates that the IGF-IR signaling axis is constitutively active in brain-seeking sublines of breast cancer cells, driving an increase in in vitro metastatic properties. We demonstrate that IGF-IR signaling is activated in an autocrine manner …

Connecting Public Libraries With Community Emergency Responders, Michelle Malizia, Karen Vargas, Rebecca Hamilton, Deborah Littrell, Cynthia Olney

Library Staff Publications

No abstract provided.

Ms 015 Guide To Joseph Melnick, Phd Papers (1943-1989), Joseph Melnick (1914-2001)

Manuscript Finding Aids

Joseph Melnick, PhD papers contains correspondence and reprints that document the career of Dr. Melnick, who was a leading epidemiologist, best known for his research on polio. See more at MS 015.

New Vaccines: How And Why Acip Makes Vaccine Recommendations; National Library Week At The Tmc Library; Basics Of Evidence-Based Practice, Vol 11. (4), Texas Medical Center Library

Insider Express (2003-2013)

No abstract provided.

Gsbs News, Spring 2013, Graduate School Of Biomedical Sciences, University Of Texas Health Science Center At Houston/M.D. Anderson Cancer Center

GSBS News

No abstract provided.

Related Resources

Journal of Applied Research on Children: Informing Policy for Children at Risk

Related Resources for New Morbidities 2.0

Beyond Bullying: Transforming The Culture Of Peer Abuse, Suellen Fried

Journal of Applied Research on Children: Informing Policy for Children at Risk

Bullying needs to be understood and positioned as a form of child abuse – peer abuse. For too many people, bullying is a benign term. This article will include information collected from a wide-range of researchers and discussions with over 50,000 students that I have facilitated during the past twenty years. The content will focus on new morbidities related to bullying such as depression and suicide, obesity, eating disorders, food allergies, juvenile diabetes, truancy, and substance and alcohol abuse. Making a cultural change in our society will require identified Change Agents, along with recommendations for collaboration, policies, projects and legislation.

Highlighting The Importance Of Researching Family Homelessness, Ronald E. Hallett, William G. Tierney

Journal of Applied Research on Children: Informing Policy for Children at Risk

This invited commentary responds to and builds upon Tobin and Murphy's article, “Addressing the Challenges of Child and Family Homelessness.” In affirming the ideas emerging from this article, Hallett and Tierney provide three points of extension: (1) more research needs to be conducted with doubled-up families; (2) the role of shame needs further exploration; and, (3) additional work needs to be done to increase access to postsecondary institutions.

Moving Upstream To Prevent Child Maltreatment, Carol Runyan

Journal of Applied Research on Children: Informing Policy for Children at Risk

Invited Commentary on "Child Maltreatment Prevention - Finding Common Ground with Unintentional Injury Prevention."

Journeying Beyond The Balcony To The Block Party And Up To 50,000 Feet: Disparities In Children’S Health And Healthcare, Yolande M. Pengetnze, Glenn Flores

Journal of Applied Research on Children: Informing Policy for Children at Risk

Invited Commentary on “Observations from the Balcony: Directions for Pediatric Health Disparities Research and Policy".

Family Structure And Early Child Health: Policy Implications And Directions For Future Research, Kristin Turney

Journal of Applied Research on Children: Informing Policy for Children at Risk

Invited commentary on "Family Matters: Links Between Family Structure and Early Child Health."

Considering Social Factors And Potential Moderation Effects In Children’S Health Research, Sharon Bzostek

Journal of Applied Research on Children: Informing Policy for Children at Risk

In light of dramatic changes in American family demography in recent decades, there is a growing recognition that family structure is one of a host of important social factors contributing to children’s health and well-being. The article by Augustine and Kimbro contributes to a growing body of research linking children’s family structure and health outcomes, focusing specifically on the association between family living arrangements and children’s risk of obesity. Their analyses are especially helpful in suggesting that family scholars should pay more attention to potential heterogeneity in relationships between family structure and children’s outcomes.

Building An Evidence-Based Approach To Address Dating Violence Prevention, Peggy B. Smith

Journal of Applied Research on Children: Informing Policy for Children at Risk

Purpose: To discuss the approach and recommendations related to the adoption of school based curriculum for violence prevention.

Findings: Preliminary assessments suggest that middle and high school youth experience a variety of forms of violence in social and dating relationships. Such experiences have negative academic, behavioral and emotional consequences.

Conclusions: The authors have clearly illuminated the need for addressing the phenomenon of dating violence. The field could benefit from more robust evidenced-based investigations that substantiate that interventions have an impact beyond attitudinal changes toward the behavior. Such academic endeavors will provide a platform to validate the inclusion of …

Nothing About Us Without Us! The Failure Of The Modern Juvenile Justice System And A Call For Community-Based Justice, Charisa Smith Esq.

Journal of Applied Research on Children: Informing Policy for Children at Risk

The modern juvenile justice system is failing our society. A literature review reveals resounding criticism of the system at all points—arrest, court processing, and incarceration. The current system does not effectively reduce recidivism, is wrought with racial disparities, operates with a minimal degree of cultural competence, violates human rights norms, and fails to empower and reform individuals who are directly affected. The current system shatters social bonds and does not hold governmental agencies accountable for wrongdoing or ineffectiveness. Community-based approaches more effectively reduce crime, cost less, are more empowering and culturally competent, help ameliorative civic fragmentation, and are more socially …

Metropolitan Observatory For Street Children And Youngsters: A Chilean Experience Of An Innovative Model, Emillia Valenzuela Vergara, Paula Margotta Meneses, Paula Bedregal García, Liliana Guerra Aburto

Journal of Applied Research on Children: Informing Policy for Children at Risk

In Chile, street children and youngsters' situations have changed significantly over the last decades. The Metropolitan Observatory is an innovative organization that makes it possible to follow this velnerable group. The Observatory is becoming a pioneering actor in the subject, thanks to the participative work and agreed consensus of different institutions involved.

The aim of this paper is to introduce the innovative cross-sectoral work done by the Metropolitan Observatory for street children and youth.

Addressing The Challenges Of Child And Family Homelessness, Kerri Tobin, Joseph Murphy

Journal of Applied Research on Children: Informing Policy for Children at Risk

Homeless children in families comprise the fastest-growing group of homeless persons in the United States. Indeed, the American Academy of Pediatrics considers homelessness to be an issue with which pediatricians should be concerned. In this article, we review existing literature to provide a background for researchers, policymakers, and social service providers hoping to understand the phenomenon of child and family homelessness and various strategies used to address it. We begin with a definition and description of the population of homeless families with children. We then offer a broad consideration of the effects of child and family homelessness, from physical health …

Child Maltreatment Prevention – Finding Common Ground With Unintentional Injury Prevention, Rohit Shenoi, Christopher Greeley, Angelo P. Giardino

Journal of Applied Research on Children: Informing Policy for Children at Risk

Child Maltreatment Prevention – Finding Common Ground with Unintentional Injury Prevention

Observations From The Balcony: Directions For Pediatric Health Disparities Research And Policy, Jean L. Raphael

Journal of Applied Research on Children: Informing Policy for Children at Risk

In 2002, the Institute of Medicine released Unequal Treatment: Confronting Racial and Ethnic Disparities in Healthcare, a landmark monograph documenting health disparities in the U.S. health care system. Since the publication of Unequal Treatment, the field of pediatric health disparities research has advanced significantly with a proliferation of studies examining a wide array of topics concerning inequities in child health. Advances in health care policy and legislation have also added to a heightened discourse on pediatric health disparities. While there has been substantial activity in efforts to address pediatric health disparities, questions remain regarding whether these efforts have changed …

Family Matters: Links Between Family Structure And Early Child Health, Laura L. Freeman, Mackenzie Brewer

Journal of Applied Research on Children: Informing Policy for Children at Risk

This paper reviews the research of the past two decades that addresses the relationship between family structure and early child health outcomes. Specifically, we focus on family structure’s influence on child health during pregnancy, birth, and infancy. We briefly summarize the most pervasive changes to family structure in the US during recent decades and discuss how early child health is linked to future outcomes for children and adults. We review research that highlights the mechanisms linking family structure to early child health and identify key risk and protective factors for children from the prenatal period through infancy. We conclude with …

Family Structure And Obesity Among U.S. Children, Jennifer M. Augustine Ph.D., Rachel T. Kimbro

Journal of Applied Research on Children: Informing Policy for Children at Risk

Child obesity in the U.S. is a significant public health issue, particularly among children from disadvantaged backgrounds. Thus, the roles of parents’ human and financial capital and racial and ethnic background have become important topics of social science and public health research on child obesity. Less often discussed, however, is the role of family structure, which is an important predictor of child well-being and indicator of family socioeconomic status. The goal of this study, therefore, is to investigate how preschool aged children’s risk of obesity varies across a diverse set of family structures and whether these differences in obesity are …

The Need For School-Based Teen Dating Violence Prevention, Jeff R. Temple, Vi D. Le, Alexandra Muir, Laurie Goforth, Amy L. Mcelhany

Journal of Applied Research on Children: Informing Policy for Children at Risk

Schools have several competing demands, and often suffer from inefficient access to needed resources. Thus, the addition of any program into an already overtaxed school system must be met with convincing evidence that 1) a need or problem exists and is relevant to the education of students, 2) the problem is amenable to change, and 3) addressing the problem is in the best interest of educators and students. The purpose of the present paper is to present a case for inclusion of teen dating violence prevention programs in middle and high schools. We also discuss a recent survey of 219 …

New Morbidities 2.0, Angelo P. Giardino, Robert D. Sanborn

Journal of Applied Research on Children: Informing Policy for Children at Risk

Robert Sanborn and Angelo Giardino's introduction for Volume 4, Issue 1: New Morbdities 2.0

All Adults Once Were Children, Robert W. Block

Journal of Applied Research on Children: Informing Policy for Children at Risk

Issue Editor, Robert Block's, point of view and summary of the articles in New Morbidities 2.0

Md Consult Being Retired By Publisher; Tmc Library Research Guide, Texas Medical Center Library

Insider Express (2003-2013)

No abstract provided.

Basics Of Evidence-Based Practice; Finding Citation Metrics; Tuesday Tech Lunch Series – Introduction To Creating E-Books, Vol 11. (3), Texas Medical Center Library

Insider Express (2003-2013)

No abstract provided.

A University System’S Approach To Enhancing The Educational Mission Of Health Science Schools And Institutions: The University Of Texas Academy Of Health Science Education, L. Maximilian Buja, Susan M. Cox, Steven A. Lieberman, Jonathan Macclements, Janet F. Williams, Robert M. Esterl Jr., Kenneth I. Shine

Library Staff Publications

Background: The academy movement developed in the United States as an important approach to enhance the educational mission and facilitate the recognition and work of educators at medical schools and health science institutions. Objectives: Academies initially formed at individual medical schools. Educators and leaders in The University of Texas System (the UT System, UTS) recognized the academy movement as a means both to address special challenges and pursue opportunities for advancing the educational mission of academic health sciences institutions. Methods: The UTS academy process was started by the appointment of a Chancellor’s Health Fellow for Education in 2004. Subsequently, the …

Ms171: Interview With Dorothy Otto, Dorothy Otto M.S.N., Ed.D., Anef, Houston Academy Of Medicine-Texas Medical Center Library

Texas Medical Center - Women's History Project

Interview with Dorothy Otto, Associate Professor at the School of Nursing, University of Texas Houston Health Science Center. See more at Texas Medical Center-Women's History Project and its finding aid.

Ms171: Interview With Anna Steinberger, Anna Steinberger Ph.D., Houston Academy Of Medicine-Texas Medical Center Library

Texas Medical Center - Women's History Project

An oral interview with Dr. Anna Steinberger, who taught and conducted basic research in Reproductive Biology and served as Assistant Dean for Faculty Affairs at UT Medical School-Houston. Her research yielded over 250 scientific articles, books, and book chapters for which she received numerous awards and recognitions in the USA and abroad. See more at Texas Medical Center-Women's History Project and its finding aid.

Ms171: Interview With Dianna Milewicz, Dianna Milewicz M.D., Ph.D., Houston Academy Of Medicine-Texas Medical Center Library

Texas Medical Center - Women's History Project

An oral interview with Dianna Milewicz, M.D., Ph.D., Professor and Vice Chairman of the Department of Internal Medicine at The University of Texas Medical School at Houston and Director of the M.D./Ph.D. Program and co-Director of the Biomedical Engineering Center. Her research interests include the genetic basis of cardiovascular diseases, and understanding the effect of identified mutations on protein function. She has recently established a genetic core laboratory to provide molecular biology and genetic expertise to clinicians who want to initiate genetic studies on their patient populations. See more at Texas Medical Center-Women's History Project and its finding aid.

Library Holiday Hours; Tuesday Tech Lunch Series – Alternatives To Powerpoint; Emerging Zoonotic Viral Infections: Do They Find Us Or Do We Find Them? Vol. 11 (2), Texas Medical Center Library

Insider Express (2003-2013)

No abstract provided.