Digital Commons Network^™

Treatment Outcomes For Inpatients With Obsessive-Compulsive Personality Disorder: An Open Comparison Trial, Ryan Smith, Christopher Shepard, Anika Wiltgen, Katrina Rufino, J Christopher Fowler

Staff and Researcher Publications

Background: The current case-control study compared rates of clinically significant and reliable change in psychopathology and global functioning, prevalence of clinical deterioration, and rates of symptom remission among adult patients with obsessive compulsive personality disorder OCPD (n=52) and well-matched inpatients with any other personality disorder (n=56) and no personality disorder (n=53).

Methods: Propensity score matching (PSM) was utilized to select patients matched on specific criteria present in the OCPD group. Multivariate analysis of variance models measured differences in admission functioning and RCI change across depression and anxiety severity, emotion dysregulation and suicidal ideation.

Results: Patients diagnosed with OCPD admit to …

Cancer Antigen 125 Is Associated With Length Of Stay In Patients With Acute Heart Failure, Hakki Kaya, Recep Kurt, Osman Beton, Ali Zorlu, Hasan Yucel, Hakan Gunes, Didem Oguz, Mehmet Birhan Yilmaz

The Texas Heart Institute Journal

Length of stay is the primary driver of heart-failure hospitalization costs. Because cancer antigen 125 has been associated with poor morbidity and mortality rates in heart failure, we investigated the relationship between admission cancer antigen 125 levels and lengths of stay in heart-failure patients. A total of 267 consecutive patients (184 men, 83 women) with acute decompensated heart failure were evaluated prospectively. The median length of stay was 4 days, and the patients were classified into 2 groups: those with lengths of stay ≤4 days and those with lengths of stay >4 days. Patients with longer lengths of stay had …

Percutaneous Valvuloplasty For Bioprosthetic Tricuspid Valve Stenosis, Gaurav Rana, Rohit Malhotra, Anjali Sharma, Nikolaos Kakouros

The Texas Heart Institute Journal

Percutaneous transcatheter tricuspid balloon valvuloplasty (PTTBV) is an accepted treatment option for symptomatic severe native tricuspid valve stenosis, although surgical tricuspid valve replacement remains the treatment of choice. There have been few reports of successful PTTBV for bioprosthetic tricuspid valve stenosis. We present case reports of 3 patients from our hospital experience. Two of the 3 cases were successful, with lasting clinical improvement, whereas the 3rd patient failed to show a reduction in valve gradient. We describe the standard technique used for PTTBV. We present results from a literature review that identified 16 previously reported cases of PTTBV for bioprosthetic …

Fare Thee Well, Dr Cooley, Herbert L Fred, James T Willerson

The Texas Heart Institute Journal

No abstract provided.

Clinical Risk Factors For Infective Endocarditis In Staphylococcus Aureus Bacteremia, Vincent Bryan D Salvador, Bikash Chapagain, Astha Joshi, Debra J Brennessel

The Texas Heart Institute Journal

Crucial to the management of staphylococcal bacteremia is an accurate evaluation of associated endocarditis, which has both therapeutic and prognostic implications. Because the clinical presentation of endocarditis can be nonspecific, the judicious use of echocardiography is important in distinguishing patients at high risk of developing endocarditis. In the presence of high-risk clinical features, an early transesophageal echocardiogram is warranted without prior transthoracic echocardiography.

The purpose of this study was to investigate the clinical risk factors for staphylococcal infective endocarditis that might warrant earlier transesophageal echocardiography and to describe the incidence of endocarditis in cases of methicillin-resistant and methicillin-sensitive Staphylococcus aureus …

Titanium Plug Closure After Heartware Ventricular Assist Device Explantation In A 15-Year-Old Girl: First Us Experience, Diego A Lara, Aamir Jeewa, Barbara A Elias, Elizabeth O Mccullum, Susan W Denfield, William J Dreyer, Iki Adachi

The Texas Heart Institute Journal

We describe the case of a teenage girl with anthracycline-induced cardiomyopathy who received a HeartWare ventricular assist device and underwent successful device explantation after cardiac recovery. During device support, the patient's cardiac function returned to normal. Twelve months after implantation, we explanted the device via repeat median sternotomy. To close the hole in the left ventricular apex and preserve the sewing ring in case future device support is needed, we used a German-manufactured titanium plug, developed specifically for this purpose. To our knowledge, this is the first use of this plug in the United States. The patient recovered uneventfully and …

Improving Outcomes For At-Risk Prekindergarten And Kindergarten Students With A Digital Learning Resource, K.P. Thai Ph.D., Leslie Ponciano Ph.D.

Journal of Applied Research on Children: Informing Policy for Children at Risk

Objective: A two-year longitudinal study examined the academic impact of the integration of ABCmouse Early Learning Academy, an online supplemental digital early learning resource, into prekindergarten and kindergarten.

Design and Participants: With a naturalistic design, ABCmouse was provided to all 230 prekindergarten students enrolled in a district-run program for students identified as at risk for school failure. The following year, the prekindergarten sample entered kindergarten and were provided with ABCmouse along with their kindergarten peers (N = 571) within a quasi-experimental design. Half of the schools received regular access to the full ABCmouse curriculum for the entire school year, …

Pre-K In Texas: A Critical Component For Academic Success, Robert Sanborn, Katie Mcconnell, Mandi Kimball, Andy Canales, Jesus Davila, Shay Everitt, Kellie O'Quinn, Claire Treacy, Carlos Villegas

Journal of Applied Research on Children: Informing Policy for Children at Risk

With funding from the Meadows Foundation and the Miles Foundation, researchers at CHILDREN AT RISK engaged in a study to examine how participation in Texas public PreKindergarten Pre-K1 is associated with performance on the 3rd Grade State of Texas Assessment of Academic Readiness (STAAR) Reading assessment.

CHILDREN AT RISK tracked approximately 47,000 students from the 2010-2011 school year to the 2014-2015 school year.2 These students began public Pre-K in 2010 and completed 3rd grade in 2015. The study focused on five major independent school districts (ISD) in Texas (Austin ISD, Dallas ISD, Fort Worth ISD, Houston ISD, and San Antonio …

Latina Women In The United States: Child Care Preferences And Arrangements, Laura Satkowski Ph.D., Rumeli Banik Ph.D., Sonia Roubeni M.A.

Journal of Applied Research on Children: Informing Policy for Children at Risk

Formal child care has been associated with myriad benefits for children, such as improvements in cognitive development and language skills. Immigrant children may derive unique benefits from formal child care, as research has also confirmed that center-based child care is associated with gains in English language proficiency and school readiness. However, immigrant families are less likely than nonimmigrant families to enroll their children in formal child care. Considering the growing immigrant population in the US—a large proportion of which is Latino—more research is needed to understand the child care decision-making processes of immigrant Latino families. The current study examined the …

Behavioral Economics And Developmental Science: A New Framework To Support Early Childhood Interventions, Lisa Gennetian, Matthew Darling, J Lawrence Aber

Journal of Applied Research on Children: Informing Policy for Children at Risk

Public policies have actively responded to an emergent social and neuroscientific evidence base documenting the benefits of targeting services to children during the earliest period of their development. But problems of low utilization, inconsistent participation, and low retention continue to present themselves as challenges. Although most interventions recognize and address structural and psycho-social barriers to parent’s engagement, few take seriously the decision making roles of parents. Using insights from the behavioral sciences, we revisit assumptions about the presumed behavior of parents in a developmental context. We then describe ways in which this framework informs features of interventions that can be …

The History Of Texas Medical Center, Texas Medical Center

TMC Reports

No abstract provided.

Annual Report 2016-2017, Houston Academy Of Medicine - Texas Medical Center Library

Annual Reports: 1943 - Present

This file contains the Annual Report for the library from 2016-2017.

Ms 104 James H. Steele, Dvm, Ph Papers (1938-­2010), James H. Steele

Manuscript Finding Aids

The James H. Steele DVM, MPH papers document the life and career of James H. Steele, who is considered the father of veterinary public health. These papers provide information about Steele's research, professional activities and correspondence, travels, and achievements. See more at MS 104.

Ms225: 2017 Faculty Meeting Minutes, Thomas R. Cole

Thomas R. Cole, PhD Papers

Original Filename: Faculty Meeting Minutes 010417.docx. Format Details: fmt/412; Microsoft Word for Windows; 2007 onwards. See more at Thomas R. Cole, PhD Papers and its finding aid.

Understanding Pubmed Search Results Using Topic Models And Interactive Information Visualization, Zhiguo Yu

Dissertations and Theses (Open Access)

With data increasing exponentially, extracting and understanding information, themes and relationships from larger collections of documents is becoming more and more important to researchers in many areas. PubMed, which comprises more than 25 million citations, uses Medical Subject Headings (MeSH) to index articles to better facilitate their management, searching and indexing. However, researchers are still challenged to find and then get a meaningful overview of a set of documents in a specific area of interest. This is due in part to several limitations of MeSH terms, including: the need to monitor and expand the vocabulary; the lack of concept coverage …

Improving Syntactic Parsing Of Clinical Text Using Domain Knowledge, Min Jiang

Dissertations and Theses (Open Access)

Syntactic parsing is one of the fundamental tasks of Natural Language Processing (NLP). However, few studies have explored syntactic parsing in the medical domain. This dissertation systematically investigated different methods to improve the performance of syntactic parsing of clinical text, including (1) Constructing two clinical treebanks of discharge summaries and progress notes by developing annotation guidelines that handle missing elements in clinical sentences; (2) Retraining four state-of-the-art parsers, including the Stanford parser, Berkeley parser, Charniak parser, and Bikel parser, using clinical treebanks, and comparing their performance to identify better parsing approaches; and (3) Developing new methods to reduce syntactic ambiguity …

Patient Predictors Of Poor Drug Sensitive Tuberculosis Treatment Outcomes In Kyiv Oblast, Ukraine, Omowunmi Aibana, Andrej Slavuckij, Mariya Bachmaha, Viatcheslav Krasiuk, Natasha Rybak, Timothy P Flanigan, Vasyl Petrenko, Megan B Murray

Faculty, Staff and Student Publications

Background: Ukraine has high rates of poor treatment outcomes among drug sensitive tuberculosis (DSTB) patients, while global treatment success rates for DSTB remain high.

We evaluated baseline patient factors as predictors of poor DSTB treatment outcomes.

Methods: We conducted a retrospective analysis of new drug sensitive pulmonary TB patients treated in Kyiv Oblast, Ukraine between November 2012 and October 2014. We defined good treatment outcomes as cure or completion and poor outcomes as death, default (lost to follow up) or treatment failure. We performed logistic regression analyses, using routine program data, to identify baseline patient factors associated with poor outcomes. …

A Rare Case Of Erythema Elevatum Diutinum Presenting As Diffuse Neuropathy, G H. Nguyen, E L. Guo, D Norris

Faculty, Staff and Students Publications

No abstract provided.

A Novel Approach To Identifying A Neuroimaging Biomarker For Patients With Serious Mental Illness, Alok Madan, J Christopher Fowler, Michelle A Patriquin, Ramiro Salas, Philip R Baldwin, Kenia M Velasquez, Humsini Viswanath, David L Molfese, Carla Sharp, Jon G Allen, Susan Hardesty, John M Oldham, B Christopher Frueh

Staff and Researcher Publications

Serious mental illness (SMI) is disabling, and current interventions are ineffective for many. This exploratory study sought to demonstrate the feasibility of applying topological data analysis (TDA) to resting-state functional connectivity data obtained from a heterogeneous sample of 235 adult inpatients to identify a biomarker of treatment response. TDA identified two groups based on connectivity between the prefrontal cortex and striatal regions: patients admitted with greater functional connectivity between these regions evidenced less improvement from admission to discharge than patients with lesser connectivity between them. TDA identified a potential biomarker of an attenuated treatment response among inpatients with SMI. Insofar …

The Neurobiological Mechanisms Of Generalized Anxiety Disorder And Chronic Stress, Michelle A Patriquin, Sanjay J Mathew

Staff and Researcher Publications

Two classification systems are now at the forefront of clinical psychiatric research: (1) Diagnostic and Statistical Manual, Fifth Edition and (2) the National Institutes of Mental Health Research Domain Criteria. Herein, we propose that these two classification systems are complementary rather than mutually exclusive, and when combined provide important information for understanding aspects of the pathophysiology related to Generalized Anxiety Disorder (GAD). The neurobiological literature for GAD and one relevant research domain criteria component, sustained threat, are reviewed from multiple units of analysis (genetic, neuroimaging, neuroendocrine, and psychophysiological). It is hypothesized that generating a comprehensive, biologically based understanding of the …

Community-Based Partnerships: Collaboration And Organizational Partnerships In Criminal Justice, Meghan E. Hollis

Journal of Family Strengths

This research examined a collaborative communitypractitioner partnership involving many justice and non-justice system agencies in Tarrant County, Texas. The study examined the challenges of a community-based partnership for solving jail overcrowding issues and the overincarceration of mentally ill individuals. This research involved working with the behavioral and mental health providers, substance abuse services providers, health services providers, police, prosecutors, defense attorneys, judges, sheriff’s office, county administration, court administration, jail staff, reentry services providers and organizations, victim services organizations, and so many more. In this paper the focus is on the importance of reducing conflict between entities that see themselves as …

Predicting Sense Of Community In A Historic Latino/Latina Neighborhood Undergoing Gentrification, Laurie A. Walker, Jesse Littman, Amanda Riphenburg-Reese, Devra Ince

Journal of Family Strengths

Neighborhoods with generational Mexican American populations may have high levels of block Social Cohesion and neighborhood Sense of Community. Streetcar-focused development via federal and local investment often spurs gentrification in neighborhoods with ethnic concentrations, which shifts neighborhood demographics towards more White and higher income households. The new residential and business investment in the neighborhood often has an impact on existing neighborhood social dynamics. This study includes mixed methods resident survey data of long term and newer residents. The qualitative data analysis informs quantitative data analysis in order to better understand resident descriptions of the impact of neighborhood streetcar focused gentrification …

Influence Of Maternal Breast Milk Ingestion On Acquisition Of The Intestinal Microbiome In Preterm Infants, Katherine E Gregory, Buck S Samuel, Pearl Houghteling, Guru Shan, Frederick M Ausubel, Ruslan I Sadreyev, W Allan Walker

Faculty, Staff and Students Publications

BACKGROUND: The initial acquisition and early development of the intestinal microbiome during infancy are important to human health across the lifespan. Mode of birth, antibiotic administration, environment of care, and nutrition have all been shown to play a role in the assembly of the intestinal microbiome during early life. For preterm infants, who are disproportionately at risk of inflammatory intestinal disease (i.e., necrotizing enterocolitis), a unique set of clinical factors influence the establishment of the microbiome. The purpose of this study was to establish the influence of nutritional exposures on the intestinal microbiome in a cohort of preterm infants early …

Head Start Since The War On Poverty: Taking On New Challenges To Address Persistent School Readiness Gaps, Pamela Joshi, Kimberly Geronimo, Dolores Acevedo-Garcia

Journal of Applied Research on Children: Informing Policy for Children at Risk

This article explores Head Start’s overall effectiveness in improving school readiness outcomes and its potential to reduce gaps in these outcomes in light of changing program goals, resource and funding capacity, and the demographic changes in the low-income child population it serves. Although not an explicit goal of the Head Start program, we assess whether and how the program can address reducing school readiness gaps between children of different racial and ethnic backgrounds and income groups. Because of changing policy priorities and targeting vulnerable groups of children with diverse needs, meeting Head Start goals within funding constraints can be challenging. …

Developing Understandings Of Collaborative Partnerships Between University And Community, Judith Harris, Rebecca Pfeffer, Bernardo Pohl, Myrna Cohen, Leigh Van Horn

Journal of Family Strengths

University faculty define collaborative partnerships with the community and examine how collaborative partnerships engender community-based research and the learning process of students in the College of Public Service. Considerations include how students are acculturated, specific benefits to learning, unanticipated benefits, and the unexpected challenges of collaborative partnerships between a university and a community.

Ms 014 Guide To William Fields, Md Papers (1930-1987), William Fields (1913-2004)

Manuscript Finding Aids

The William Fields, MD papers contain scientific meeting booklets, academic books, binders containing case histories, research, symposium notes, and correspondence relating to the publication of his research of materials related to his career in Neurology. The collection consists of five boxes and equals 2.5 cubic feet. See more at MS 014.

Ms 012 Guide To Dorothea Kassell Papers (1946-1982), Dorothea Kassell 1946-1982

Manuscript Finding Aids

The Dorothea Kassell, RN papers contains newsletters, committee reports, memos, annual reports, business meeting minutes relating to the Houston Area Association of Occupational Health Nurses and Houston Area Association of Industrial Nurses, print campaigns, reprints, and other printed materials which document the career and experience of Dorothea Kassel’s career as an occupational health nurse. See more at MS 012.

Leveraging University-School District Research Partnerships: Exploring The Longitudinal Effects Of An Early Kindergarten Transition Program, Beth Tarasawa, Nicole C. Ralson, Jacqueline Waggoner

Journal of Applied Research on Children: Informing Policy for Children at Risk

With increasingly tight budgets, many public school districts lack research personnel to evaluate program efficacy or investigate best practices that raise student achievement. We highlight an example of a successful university-district partnership that offers district-driven research support while providing opportunities for practitioner-scholars to learn first-hand how to perform rigorous evaluation work. This article details the Early Kindergarten Transition program evaluation study conducted by a university-district partnership as well as testimony from district leadership on the utility of the research deliverables and long-term benefits of the research collaboration.

Ms 019 Guide To Matilda Benyesh-Melnick, Md Papers (1956-1974), Matilda Benyesh-Melnick (1926-2020)

Manuscript Finding Aids

The Matilda Benyesh-Melnick, MD papers contain research journals, reprints, magazines, reports, symposia and an undated manuscript related to her career in virology. Materials focus on the research that she conducted and collected between 1956 and 1974. See more at MS 019.

Neurogenic Megacolon In Spinal Cord Injury, Rukma R Govindu, Michelle Kelley

Faculty, Staff and Student Publications

No abstract provided.