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45-Nm Cds Qds Photoluminescent Filter For Photovoltaic Conversionefficiency Recovery, Victor Juárez-Luna, Daniel Sauceda-Carvajal, Ivett Zavala-Guillen, Enrique Rodarte-Guajardo, Francisco Carranza-Chávez, Carlos Villa Angulo
45-Nm Cds Qds Photoluminescent Filter For Photovoltaic Conversionefficiency Recovery, Victor Juárez-Luna, Daniel Sauceda-Carvajal, Ivett Zavala-Guillen, Enrique Rodarte-Guajardo, Francisco Carranza-Chávez, Carlos Villa Angulo
Turkish Journal of Electrical Engineering and Computer Sciences
Different energy loss mechanisms have restricted the breakthroughs in concentrated photovoltaic/thermal (CPVT) hybrid solar systems that use photoluminescent filters. Re?ected and transmitted light, emission spectrum, nonideal absorption, Stokes shift (proportional to $f_1 f_2$), overlapping absorption, and scattering of light are mechanisms in photoluminescent filters that restrict optical efficiency to below theoretical limits. In addition, increases in temperature by light concentration affect the operation of photovoltaic cells and photoluminescent filters because of an increase in molecular motion and collisions that consequently lead to energy loss. Meanwhile, nanocrystals or quantum dots (QDs) from groups II VI hold electrical, optical, chemical, and physical …
Analyzing Probabilistic Optimal Power Flow Problem By Cubature Rules, Qing Xiao
Analyzing Probabilistic Optimal Power Flow Problem By Cubature Rules, Qing Xiao
Turkish Journal of Electrical Engineering and Computer Sciences
This paper is devoted to revealing some properties of the probabilistic optimal power flow (POPF) problem. In conjunction with Hermite polynomial model, Nataf transformation is introduced to map POPF problem to the independent standard normal space. Firstly, a multivariate polynomial model is employed to represent the function relationship between POPF inputs and outputs. Then, moment matching equations are derived to characterize the uncertainty effects of POPF inputs on outputs; three cubature rules are derived to calculate statistical moments of POPF outputs. Finally, along with Monte Carlo simulation method, the proposed methods are tested on IEEE 57-bus system and IEEE 118-bus …
A Bi-Level Charging Management Approach For Electric Truck Charging Stationconsidering Power Losses, Tayfur Gökçek, Mehmet Tan Turan, Yavuz Ateş, Ahmet Yi̇ği̇t Arabul
A Bi-Level Charging Management Approach For Electric Truck Charging Stationconsidering Power Losses, Tayfur Gökçek, Mehmet Tan Turan, Yavuz Ateş, Ahmet Yi̇ği̇t Arabul
Turkish Journal of Electrical Engineering and Computer Sciences
This article presents an optimized heavy duty electric truck charging station (ETCS) design based on bi-level mixed integer linear programming. Electric truck parameters are integrated with the grid model and charging sequences are firstly formulated to optimize charging stages. As the second level of the optimization stage, line losses are aimed to be minimized for the charging station. ETCS model is obtained from actual parameters of the Istanbul Muratbey Customs zone which is one of the busiest customs zone in Europe and an ideal location for ETCS application in the future. The ETCS is equipped with roof type photovoltaic (PV) …
Tara: Temperature Aware Online Dynamic Resource Allocation Scheme For Energyoptimization In Cloud Data Centres, Narayanamoorthi Thilagavathi, Arockiasamy John Prakash, Sridhar Sridevi, Vaidyanathan Rhymend Uthariaraj
Tara: Temperature Aware Online Dynamic Resource Allocation Scheme For Energyoptimization In Cloud Data Centres, Narayanamoorthi Thilagavathi, Arockiasamy John Prakash, Sridhar Sridevi, Vaidyanathan Rhymend Uthariaraj
Turkish Journal of Electrical Engineering and Computer Sciences
Cloud data centres, which are characteristic of dynamic workloads, if not optimized for energy consumption, may lead to increased heat dissipation and eventually impact the environment adversely. Consequently, optimizing the usage of energy has become a hard requirement in today's cloud data centres wherein the major part of energy consumption is mostly attributed to computing and cooling systems. Motivated by which this paper proposes an online algorithm for dynamic resource allocation, namely, temperature aware online dynamic resource allocation algorithm (TARA). TARA demonstrates a novel algorithm design to adapt dynamic resource allocation based on the temperature of a data centre using …
Visual Interpretability Of Capsule Network For Medical Image Analysis, Mighty Abra Ayidzoe, Yu Yongbin, Patrick Kwabena Mensah, Jingye Cai, Faiza Umar Bawah
Visual Interpretability Of Capsule Network For Medical Image Analysis, Mighty Abra Ayidzoe, Yu Yongbin, Patrick Kwabena Mensah, Jingye Cai, Faiza Umar Bawah
Turkish Journal of Electrical Engineering and Computer Sciences
Deep learning (DL) models are currently not widely deployed for critical tasks such as in health. This is attributable to the "black box", making it difficult to gain the trust of practitioners. This paper proposes the use of visualizations to enhance performance verification, improve monitoring, ensure understandability, and improve interpretability needed to gain practitioners' confidence. These are demonstrated through the development of a CapsNet model for the recognition of gastrointestinal tract infection. The gastrointestinal tract comprises several organs joined in a long tube from the mouth to the anus. It is susceptive to diseases that are difficult for medics to …
Biometric Identification Using Panoramic Dental Radiographic Images Withfew-Shot Learning, Musa Ataş, Cüneyt Özdemi̇r, İsa Ataş, Burak Ak, Esma Özeroğlu
Biometric Identification Using Panoramic Dental Radiographic Images Withfew-Shot Learning, Musa Ataş, Cüneyt Özdemi̇r, İsa Ataş, Burak Ak, Esma Özeroğlu
Turkish Journal of Electrical Engineering and Computer Sciences
Determining identity is a crucial task especially in the cases of mass disasters such as tsunamis, earthquakes, fires, epidemics, and in forensics. Although there are various studies in the literature on biometric identification from radiographic dental images, more research is still required. In this study, a panoramic dental radiographic (PDR) imagebased human identification system was developed using a customized deep convolutional neural network model in a few-shot learning scheme. The proposed model (PDR-net) was trained on 600 PDR images obtained from a total of 300 patients. As the PDR images of the patients were very different in terms of pose …
Cover And Contents
Turkish Journal of Electrical Engineering and Computer Sciences
No abstract provided.
Improving Utilization Rate Of Semi-Parallel Successive Cancellation Architecture For Polar Codes Using 2-Bit Decoding, Dinesh Kumar Devadoss, Shantha Selva Kumari Rama Packiam
Improving Utilization Rate Of Semi-Parallel Successive Cancellation Architecture For Polar Codes Using 2-Bit Decoding, Dinesh Kumar Devadoss, Shantha Selva Kumari Rama Packiam
Turkish Journal of Electrical Engineering and Computer Sciences
Polar codes are the capacity-achieving error-correcting code proved to be a significant invention in coding theory. It can achieve channel capacity at infinite code length N due to its explicit code construction. However, the processing complexity along with the higher latency due to successive cancellation (SC) decoding is being a major design issue, which reduces the utilization rate in the decoder architectures. This paper presents a modified semi-parallel architecture for decoding polar code with a better decoding latency. Precomputation and look-ahead techniques are used to generate two bits in the final stage. Pipelined partial-sum unit with a less critical path …
Developing A Fake News Identification Model With Advanced Deep Languagetransformers For Turkish Covid-19 Misinformation Data, Mehmet Bozuyla, Akin Özçi̇ft
Developing A Fake News Identification Model With Advanced Deep Languagetransformers For Turkish Covid-19 Misinformation Data, Mehmet Bozuyla, Akin Özçi̇ft
Turkish Journal of Electrical Engineering and Computer Sciences
The massive use of social media causes rapid information dissemination that amplifies harmful messages such as fake news. Fake-news is misleading information presented as factual news that is generally used to manipulate public opinion. In particular, fake news related to COVID-19 is defined as 'infodemic' by World Health Organization. An infodemic is a misleading information that causes confusion which may harm health. There is a high volume of misinformation about COVID-19 that causes panic and high stress. Therefore, the importance of development of COVID-19 related fake news identification model is clear and it is particularly important for Turkish language from …
Event-Related Microblog Retrieval In Turkish, Çağri Toraman
Event-Related Microblog Retrieval In Turkish, Çağri Toraman
Turkish Journal of Electrical Engineering and Computer Sciences
Microblogs, such as tweets, are short messages in which users are able to share any opinion and information. Microblogs are mostly related to real-life events reported in news articles. Finding event-related microblogs is important to analyze online social networks and understand public opinion on events. However, finding such microblogs is a challenging task due to the dynamic nature of microblogs and their limited length. In this study, assuming that news articles are given as queries and microblogs as documents, we find event-related microblogs in Turkish. In order to represent news articles and microblogs, we examine encoding methods, namely traditional bag-of-words …
Identification Of Gain And Phase Margins Based Robust Stability Regions For Atime-Delayed Micro-Grid System Including Fractional-Order Controller In Presenceof Renewable Power Generation, Hakan Gündüz, Şahi̇n Sönmez, Saffet Ayasun
Identification Of Gain And Phase Margins Based Robust Stability Regions For Atime-Delayed Micro-Grid System Including Fractional-Order Controller In Presenceof Renewable Power Generation, Hakan Gündüz, Şahi̇n Sönmez, Saffet Ayasun
Turkish Journal of Electrical Engineering and Computer Sciences
This study examines the gain and phase margins (GPMs) based robust stability margins in the parameter space of fractional order proportional-integral (FOPI) controller for a micro-grid (MG) system with communication time delays. Fluctuations in renewable energy sources (RESs), uncertainties in parameters of system components and communication delays could adversely affect the dynamical analysis and frequency stability of the MG system. Such a MG system has an interval characteristic due to the parametric variations and the interval transfer functions defined by Kharitonov's theorem, which presents a solution for checking of robust stability. Therefore, this study addresses the robust stability regions containing …
Investigations On Cogging Torque Mitigation Techniques Of Transverse Flux Motorfor Direct Drive Low-Speed Spacecraft Applications, Ravichandran Mh, Venkatakirthiga Murali, Haridas Tr
Investigations On Cogging Torque Mitigation Techniques Of Transverse Flux Motorfor Direct Drive Low-Speed Spacecraft Applications, Ravichandran Mh, Venkatakirthiga Murali, Haridas Tr
Turkish Journal of Electrical Engineering and Computer Sciences
The transverse flux motor (TFM) is an ideal choice for direct drive high torque applications owing to its proven higher torque density compared to the radial flux and axial flux motors. TFM motors have several merits to be used for spacecraft applications, considering the everlasting demand of the industry for reduction in power and mass. This paper investigates the various cogging torque mitigation techniques for transverse flux motor to be effectively used as the drive motor for precise position control spacecraft requirement. The paper discusses the basic design variables of surface mounted TFM (SM-TFM) that are to be considered for …
Cryptographically Strong Random Number Generation Using Integrated Cmosphotodiodes For Low-Cost Microcontroller Based Applications, Baykal Sarioğlu
Cryptographically Strong Random Number Generation Using Integrated Cmosphotodiodes For Low-Cost Microcontroller Based Applications, Baykal Sarioğlu
Turkish Journal of Electrical Engineering and Computer Sciences
In this work, we propose a method to generate random numbers for low-cost, low-power, resource-limited low data-rate microcontrollers using integrated CMOS photodiodes. The proposed method utilizes an integrated CMOS photodiode in the photovoltaic mode as the entropy source. The method is based on serially capturing analog values derived from the integrated CMOS photodiode. The entropy of these values increased by a custom algorithm. The proposed random number generator is devised using an integrated CMOS photodiode manufactured in 180 nm standard CMOS technology. The wide applicably of the random number generator is demonstrated by realizing it on a lowcost Arduino UNO …
Long-Term Traffic Flow Estimation: A Hybrid Approach Using Location-Basedtraffic Characteristic, Tuğberk Ayar, Ferhat Atli̇nar, Mehmet Amaç Güvensan, Hafi̇za İrem Türkmen
Long-Term Traffic Flow Estimation: A Hybrid Approach Using Location-Basedtraffic Characteristic, Tuğberk Ayar, Ferhat Atli̇nar, Mehmet Amaç Güvensan, Hafi̇za İrem Türkmen
Turkish Journal of Electrical Engineering and Computer Sciences
Traffic speed estimation plays a key role in various situations, ranging from individual's trip planning to urban traffic management. Despite many studies on short-term prediction, there is only a limited number of studies focusing on long-term prediction and only a couple of them does go beyond 24 h. On the contrary, this study presents a novel hybrid architecture using location-based traffic characteristic for traffic speed estimation up to 7 days. In this architecture, the introduced mean filtering estimation (MFE) model and long short-term memory (LSTM) neural network are jointly utilized for minimizing the error for traffic flow estimation. Both MFE …
Privacy Preserving Scheme For Document Similarity Detection, Ayad Abdulsada, Salah Al-Darraji, Dhafer Honi
Privacy Preserving Scheme For Document Similarity Detection, Ayad Abdulsada, Salah Al-Darraji, Dhafer Honi
Turkish Journal of Electrical Engineering and Computer Sciences
The problem of detecting similar documents plays an essential role for many real-world applications, such as copyright protection and plagiarism detection. To protect data privacy, the new version of such a problem becomes more challenging, where the matched documents are distributed among two or more parties and their privacy should be preserved. In this paper, we propose new privacy-preserving document similarity detection schemes by utilizing the locality-sensitive hashing technique, which can handle the misspelled mistakes. Furthermore, the keywords' occurrences of a given document are integrated into its underlying representation to support a better ranking for the returned results. We introduced …
On An Electrostatic Micropump With A Rigorous Mathematical Model, İbrahi̇m Efe, Fati̇h Di̇kmen, Yury Tuchkin
On An Electrostatic Micropump With A Rigorous Mathematical Model, İbrahi̇m Efe, Fati̇h Di̇kmen, Yury Tuchkin
Turkish Journal of Electrical Engineering and Computer Sciences
The novel electrostatic micropump model for applications such as in biomedical drug delivery is presented. The geometrical arrangement of the coupling rigid electrodes lets us exploit our mathematically rigorous boundary integral equation formulation and its solution. Thus, the charge densities involving the fringe effects on the plates are obtained by means of analytical regularization method (ARM) constructed for annular strips earlier. The efficiency of the constructed method is demonstrated with respect to the direct integral equation solvers implemented via the entire domain Galerkin method and point matching. The main physical characteristics of the suggested system and their deviation from that …
A New Classification Method Using Soft Decision-Making Based On An Aggregation Operator Of Fuzzy Parameterized Fuzzy Soft Matrices, Samet Memi̇ş, Serdar Engi̇noğlu, Uğur Erkan
A New Classification Method Using Soft Decision-Making Based On An Aggregation Operator Of Fuzzy Parameterized Fuzzy Soft Matrices, Samet Memi̇ş, Serdar Engi̇noğlu, Uğur Erkan
Turkish Journal of Electrical Engineering and Computer Sciences
Recently, a precise and stable machine learning algorithm, i.e. eigenvalue classification method (EigenClass), has been developed by using the concept of generalised eigenvalues in contrast to common approaches, such as k-nearest neighbours, support vector machines, and decision trees. In this paper, we offer a new classification algorithm called fuzzy parameterized fuzzy soft aggregation classifier (FPFS-AC) to combine the modelling ability of soft decision-making (SDM) and classification success of generalised eigenvalues. FPFS-AC constructs a decision matrix by employing the similarity measures of fuzzy parameterized fuzzy soft matrices fpfs -matrices) and a generalised eigenvalue-based similarity measure. Then, it applies an SDM method …
Defect Classification Of Railway Fasteners Using Image Preprocessing And Alightweight Convolutional Neural Network, İlhan Aydin, Mehmet Sevi̇, Mehmet Umut Salur, Erhan Akin
Defect Classification Of Railway Fasteners Using Image Preprocessing And Alightweight Convolutional Neural Network, İlhan Aydin, Mehmet Sevi̇, Mehmet Umut Salur, Erhan Akin
Turkish Journal of Electrical Engineering and Computer Sciences
Railway fasteners are used to securely fix rails to sleeper blocks. Partial wear or complete loss of these components can lead to serious accidents and cause train derailments. To ensure the safety of railway transportation, computer vision and pattern recognition-based methods are increasingly used to inspect railway infrastructure. In particular, it has become an important task to detect defects in railway tracks. This is challenging since rail track images are acquired using a measuring train in varying environmental conditions, at different times of day and in poor lighting conditions, and the resulting images often have low contrast. In this study, …
Performance Analysis Of Lightweight Internet Of Things Devices On Blockchainnetworks, Cem Kösemen, Gökhan Dalkiliç, Şafak Öksüzer
Performance Analysis Of Lightweight Internet Of Things Devices On Blockchainnetworks, Cem Kösemen, Gökhan Dalkiliç, Şafak Öksüzer
Turkish Journal of Electrical Engineering and Computer Sciences
Potential integration or cooperation of the Internet of things (IoT) systems and the blockchain technology is nowadays attracting remarkable interest from the researchers. These inter-operating systems often have to rely on lowcost, low-power, and robust IoT devices that can communicate with the blockchain network through smart contracts. In this work, we designed and ran a benchmark study for ESP32-based lightweight IoT devices interacting within the Quorum blockchain. A software library was built for ESP32 devices to enable elliptic-curve digital signing, Keccak-256 hashing, decoding, encoding, and secure private key generation capabilities, which all are the basic functional requirements for running a …
Tri-Op Redactable Blockchains With Block Modification, Removal, And Insertion, Mohammad Sadeq Dousti, Alpteki̇n Küpçü
Tri-Op Redactable Blockchains With Block Modification, Removal, And Insertion, Mohammad Sadeq Dousti, Alpteki̇n Küpçü
Turkish Journal of Electrical Engineering and Computer Sciences
In distributed computations and cryptography, it is desirable to record events on a public ledger, such that later alterations are computationally infeasible. An implementation of this idea is called blockchain, which is a distributed protocol that allows the creation of an immutable ledger. While such an idea is very appealing, the ledger may be contaminated with incorrect, illegal, or even dangerous data, and everyone running the blockchain protocol has no option but to store and propagate the unwanted data. The ledger is bloated over time, and it is not possible to remove redundant information. Finally, missing data cannot be inserted …
Blocksim-Net: A Network-Based Blockchain Simulator, Prashanthi Ramachandran, Nandini Agrawal, Osman Bi̇çer, Alpteki̇n Küpçü
Blocksim-Net: A Network-Based Blockchain Simulator, Prashanthi Ramachandran, Nandini Agrawal, Osman Bi̇çer, Alpteki̇n Küpçü
Turkish Journal of Electrical Engineering and Computer Sciences
Since its proposal by Eyal and Sirer (CACM '13), selfish mining attacks on proof-of-work blockchains have been studied extensively. The main body of this research aims at both studying the extent of its impact and defending against it. Yet, before any practical defense is deployed in a real world blockchain system, it needs to be tested for security and dependability. However, real blockchain systems are too complex to conduct any test on or benchmark the developed protocols. Instead, some simulation environments have been proposed recently, such as BlockSim (Maher et al., SIGMETRICS Perform. Eval. Rev. '19), which is a modular …
Block Size Optimization For Pow Consensus Algorithm Based Blockchainapplications By Using Whale Optimization Algorithm, Betül Aygün, Hi̇lal Arslan
Block Size Optimization For Pow Consensus Algorithm Based Blockchainapplications By Using Whale Optimization Algorithm, Betül Aygün, Hi̇lal Arslan
Turkish Journal of Electrical Engineering and Computer Sciences
Blockchain-based applications come up with cryptocurrencies, especially Bitcoin, introducing a distributed ledger technologies for peer-to-peer networks and essentially records the transactions in blocks containing hash value of the previous blocks. Block generation constitutes the basis of this technology, and the optimization of such systems is among the most crucial concerns. Determining either the block size or the number of transactions in the block brings out a remarkable problem that has been solved by the miners in recent years. First, higher block size results in higher transaction time, on the other hand, smaller block size has many disadvantages such as security, …
Estonian Internet Voting With Anonymous Credentials, İsa Sertkaya, Peter Roenne, Peter Y. A. Ryan
Estonian Internet Voting With Anonymous Credentials, İsa Sertkaya, Peter Roenne, Peter Y. A. Ryan
Turkish Journal of Electrical Engineering and Computer Sciences
The Estonian Internet voting (EIV) scheme is a unique example of a long-term nation-wide, legally binding electronic voting deployment. The EIV scheme is used in parallel with standard paper-based election day voting, of course invalidating an already cast i-vote. This necessarily requires careful authentication of the eligible voters and makes the Estonian identity card solution a crucial part of the scheme, however, note that Parsovs has recently drawn attention to the security flaws found in Estonian ID-cards. In this study, we propose an e-voting scheme EIV-AC that integrates the EIV scheme with anonymous credentials based on self-sovereign identity. In addition …
Forming A Decentralized Research Network: Ds4h, Eni̇s Karaarslan, Meli̇h Bi̇ri̇m, Hüseyi̇n Emre Ari
Forming A Decentralized Research Network: Ds4h, Eni̇s Karaarslan, Meli̇h Bi̇ri̇m, Hüseyi̇n Emre Ari
Turkish Journal of Electrical Engineering and Computer Sciences
There is a trend toward decentralized systems, but these systems are developed without conducting enough software tests. Also, the performance, scalability, and sustainability of the decentralized systems are not taken into account. One of the reasons is the time-consuming testing process. The other is the hardware requirements and the complexity of the software installations of the testing environment. Developer communities need stable and secure research networks to test and develop prototypes before releasing the working versions. Cloud-based blockchain test networks are available, but it allows using a specific framework. Also, users are required to learn how to use each framework. …
Data Immutability And Event Management Via Blockchain In The Internet Of Things, Hakan Altaş, Gökhan Dalkiliç, Umut Can Çabuk
Data Immutability And Event Management Via Blockchain In The Internet Of Things, Hakan Altaş, Gökhan Dalkiliç, Umut Can Çabuk
Turkish Journal of Electrical Engineering and Computer Sciences
The Internet of things (IoT) is the key enabler of the smart systems used in many areas, from agriculture to aviation, industrial automation to autonomous vehicles. Most IoT deployments employ cost-efficient lightweight devices with limited resources (e.g., bandwidth, energy, storage). Although an IoT network must be built in its simplest form, engineers include more sophisticated devices like gateways and servers to provide web-based services and benefit from cloud systems. So, although the nodes can be widely distributed geographically or topologically, the system becomes centralized, which causes bottlenecks and single-points-of-failure. Furthermore, providing data integrity, nonrepudiation, and event management becomes tricky. In …
Cover And Contents
Turkish Journal of Electrical Engineering and Computer Sciences
No abstract provided.
Privacy In Blockchain Systems, Murat Osmanoğlu, Ali̇ Aydin Selçuk
Privacy In Blockchain Systems, Murat Osmanoğlu, Ali̇ Aydin Selçuk
Turkish Journal of Electrical Engineering and Computer Sciences
Privacy of blockchains has been a matter of discussion since the inception of Bitcoin. Various techniques with a varying degree of privacy protection and complexity have been proposed over the past decade. In this survey, we present a systematic analysis of these proposals in four categories: (i) identity, (ii) transaction, (iii) consensus, and (iv) smart contract privacy. Each of these categories have privacy requirements of its own, and various solutions have been proposed to meet these requirements. Almost every technique in the literature of privacy enhancing technologies have been applied to blockchains: mix networks, zero-knowledge proofs, blind signatures, ring signatures, …
Permissioned Blockchain Based Remote Electronic Examination, Öznur Kalkar, İsa Sertkaya
Permissioned Blockchain Based Remote Electronic Examination, Öznur Kalkar, İsa Sertkaya
Turkish Journal of Electrical Engineering and Computer Sciences
Recent coronavirus pandemic transformed almost all aspects of daily life including educational institutions and learning environments. As a result, this transformation brought remote electronic examination (shortly e-exam) concepts back into consideration. In this study, we revisit secure and privacy preserving e-exam protocol proposals and propose an e-exam protocol that utilizes decentralized identity-based verifiable credentials for proof of authentication and public-permissioned blockchain for immutably storing records. In regard to the previously proposed e-exam schemes, our scheme offers both privacy enhancement and better efficiency. More concretely, the proposed solution satisfies test answer authentication, examiner authentication, anonymous marking, anonymous examiner, question secrecy, question …
Transcriptomic Profiling Of Mice Brain Under Bex3 Regulation, Zhimin Xu, Noor Bahadar, Yingxin Zhang, Shuang Tan, Zhongze Wang, Bingyi Ren, Shitao Liu, Huanyan Dai, Yaowu Zheng, Bing Han
Transcriptomic Profiling Of Mice Brain Under Bex3 Regulation, Zhimin Xu, Noor Bahadar, Yingxin Zhang, Shuang Tan, Zhongze Wang, Bingyi Ren, Shitao Liu, Huanyan Dai, Yaowu Zheng, Bing Han
Turkish Journal of Biology
BEX family genes are expressed in various tissues and play significant roles in neuronal development. A mouse model of Bex3 gene knock-out was generated in this study, using the CRISPR-Cas9 system. Transcriptomic analysis of the brain was performed to identify genes and pathways under Bex3 regulation. Essential biological functions under the control of Bex3 related to brain development were identified. Ninety-five genes were differentially expressed under Bex3-/- regulation, with 53 down and 42 up. Among down-regulated genes, LOC102633156 is a member of zf-C2H2, Xlr3a is an X-linked lymphocyte regulated gene, LOC101056144 is a hippocampal related gene, 2210418O10Rik and Fam205a3 are …
Modeling Of C-Terminal Tail Of Human Sting And Its Interaction With Tank-Binding Kinase 1, Rahaf Ata Ouda Al-Masri, Hajara Audu-Bida, Şebnem Eşsi̇z
Modeling Of C-Terminal Tail Of Human Sting And Its Interaction With Tank-Binding Kinase 1, Rahaf Ata Ouda Al-Masri, Hajara Audu-Bida, Şebnem Eşsi̇z
Turkish Journal of Biology
Stimulator of interferon genes (STING) plays a significant role in a cell's intracellular defense against pathogens or self-DNA by inducing inflammation or apoptosis through a pathway known as cGAS-cGAMP-STING. STING uses one of its domains, the C-terminal tail (CTT) to recruit the members of the pathway. However, the structure of this domain has not been solved experimentally. STING conformation is open and more flexible when inactive. When STING gets activated by cGAMP, its conformation changes to a closed state covered by 4 beta-sheets over the binding site. This conformational change leads to its binding to Tank-binding kinase 1 (TBK1). TBK1 …