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The Impact Of Donor And Recipient Kir Genes And Kir Ligands On The Occurrence Of Acutegraft-Versus-Host Disease And Graft Survival After Hla-Identical Sibling Hematopoieticstem Cell Transplantation, Seyed Ahmad Hoseinian, Davood Jafari, Mehdi Mahmoodi, Kamran Alimoghaddam, Mohammadreza Ostadali, Azita Talebzadeh Bonakdar, Arron Munggela Foma, Mir Saeed Yekaninejad, Ali Akbar Amirzargar
The Impact Of Donor And Recipient Kir Genes And Kir Ligands On The Occurrence Of Acutegraft-Versus-Host Disease And Graft Survival After Hla-Identical Sibling Hematopoieticstem Cell Transplantation, Seyed Ahmad Hoseinian, Davood Jafari, Mehdi Mahmoodi, Kamran Alimoghaddam, Mohammadreza Ostadali, Azita Talebzadeh Bonakdar, Arron Munggela Foma, Mir Saeed Yekaninejad, Ali Akbar Amirzargar
Turkish Journal of Medical Sciences
Background/aim: After allogeneic hematopoietic stem cell transplantation (allo-HSCT), donor natural killer (NK) cells trigger alloreactions against potential recipient cells by their killer immunoglobulin-like receptors (KIRs). This study investigated whether KIR/HLA genotypes and KIR haplotypes of donors and recipients exhibit a critical function in the prevalence of acute graft-versus-host disease (aGVHD) and persistence of the graft after HLA-identical sibling allo-HSCT for patients with hematological malignancies. Materials and methods: We studied KIR and HLA genotypes in 115 related donors and recipients (56 patients with AML and 59 patients with ALL) who had received allo-HSCT from HLA-matched sibling donors. We evaluated 17 KIR …
The In Vitro Effect Of Antimicrobial Photodynamic Therapy Oncandida And Staphylococcus Biofilms, Özlem Güzel Tunçcan, Ayşe Kalkanci, Eli̇f Ayça Ünal, Olkar Abdulmajed, Merve Erdoğan, Murat Di̇zbay, Kayhan Çağlar
The In Vitro Effect Of Antimicrobial Photodynamic Therapy Oncandida And Staphylococcus Biofilms, Özlem Güzel Tunçcan, Ayşe Kalkanci, Eli̇f Ayça Ünal, Olkar Abdulmajed, Merve Erdoğan, Murat Di̇zbay, Kayhan Çağlar
Turkish Journal of Medical Sciences
Background/aim: This study was designed to evaluate the effect of antimicrobial photodynamic treatment (APDT) in a biofilm model using combinations of various dyes (rose bengal, riboflavin, and methylene blue) as photosensitizers and light sources (LED and UVA) against staphylococcal and candidal biofilms. Materials and methods: Sterile microtiter plates were used for the development and quantification of the biofilms. APDT was carried out using combinations of the light sources and dyes. The percentage of the growth inhibition was then calculated using a spectrophotometer. The broth media in the wells were aspirated, wells were stained with crystal violet, and optical density values …
Octreotide Ameliorates Dermal Fibrosis In Bleomycin-Induced Scleroderma, Si̇bel Oyucu Orhan, Ahmet Tektemur, Nevzat Gözel, İbrahi̇m Hani̇fi̇ Özercan, Servet Yolbaş, Ahmet Yildirim, Ebru Önalan, Süleyman Serdar Koca
Octreotide Ameliorates Dermal Fibrosis In Bleomycin-Induced Scleroderma, Si̇bel Oyucu Orhan, Ahmet Tektemur, Nevzat Gözel, İbrahi̇m Hani̇fi̇ Özercan, Servet Yolbaş, Ahmet Yildirim, Ebru Önalan, Süleyman Serdar Koca
Turkish Journal of Medical Sciences
Background/aim: Insulin-like growth factor (IGF)-I is a differentiation and growth factor. Antifibrotic action of octreotide has been reported in pulmonary fibrosis. The present study aimed to research the prophylactic and therapeutic potential of octreotide on a bleomycin (BLM)-induced experimental scleroderma model. Materials and methods: Sixty Balb/c female mice were divided into 6 groups. Daily subcutaneous BLM (100 μg) was injected for 3 weeks in groups II and III and for 6 weeks in groups V and VI. Octreotide (100 μg/kg per day) was injected subcutaneously for the first 3 weeks in group III (prophylactic) and the second 3 weeks in …
Hand Functions In Systemic Lupus Erythematosus: A Comparative Study With Rheumatoidarthritis Patients And Healthy Subjects, Songül Bağlan Yentür, Zeynep Tuna, Oğuzhan Mete, Ahmet Gökkurt, Nurten Gi̇zem Tore, Hami̇t Küçük, Berna Göker, Deran Oskay
Hand Functions In Systemic Lupus Erythematosus: A Comparative Study With Rheumatoidarthritis Patients And Healthy Subjects, Songül Bağlan Yentür, Zeynep Tuna, Oğuzhan Mete, Ahmet Gökkurt, Nurten Gi̇zem Tore, Hami̇t Küçük, Berna Göker, Deran Oskay
Turkish Journal of Medical Sciences
Background/aim: Systemic lupus erythematosus (SLE) frequently affects the small joints of the hand and may result in difficulty in activities of daily living. There are very few studies evaluating the problems encountered in the hands in patients with SLE. The aim of this study is to evaluate hand functions in patients with SLE and compare them with rheumatoid arthritis (RA) patients and healthy subjects. Materials and methods: A total 46 female patients meeting the SLE classification criteria were recruited. Similarly, 51 female RA patients and 46 healthy female subjects served as the control groups. To assess the upper extremity disability …
Methodology Of A New Inflammatory Arthritis Registry: Treasure, Umut Kalyoncu, Etem Koray Taşcilar, Ali̇ İhsan Ertenli̇, Hüseyi̇n Edi̇z Dalkiliç, Cemal Bes, Orhan Küçükşahi̇n, Ti̇muçi̇n Kaşi̇foğlu, Ni̇lüfer Alpay Kanitez, Hakan Emmungi̇l, Gezmi̇ş Ki̇myon, Nazi̇fe Şule Yaşar Bi̇lge, Servet Akar, Mehmet Pami̇r Atagündüz, Süleyman Serdar Koca, Aşkin Ateş
Methodology Of A New Inflammatory Arthritis Registry: Treasure, Umut Kalyoncu, Etem Koray Taşcilar, Ali̇ İhsan Ertenli̇, Hüseyi̇n Edi̇z Dalkiliç, Cemal Bes, Orhan Küçükşahi̇n, Ti̇muçi̇n Kaşi̇foğlu, Ni̇lüfer Alpay Kanitez, Hakan Emmungi̇l, Gezmi̇ş Ki̇myon, Nazi̇fe Şule Yaşar Bi̇lge, Servet Akar, Mehmet Pami̇r Atagündüz, Süleyman Serdar Koca, Aşkin Ateş
Turkish Journal of Medical Sciences
Background/aim: The TReasure registry, created in 2017, is an observational multicenter cohort that includes inflammatory arthritis patients. This article reviews the methodology and objectives of the TReasure registry established to collect data from rheumatoid arthritis (RA) and spondyloarthritis (SpA) patients. Methodology: Fifteen rheumatology centers in Turkey will contribute data to the TReasure database. The actual proprietor of the database is the Hacettepe Rheumatology Association (HRD) and Hacettepe Financial Enterprises. Pharmaceutical companies that operate in Turkey (in alphabetical or er), Abbvie, Amgen, BMS, Celltrion Healthcare, Novartis, Pfizer, Roche, and UCB, support the TReasure registry. TReasure is a web-based database to which …
Multitarget Therapy Versus Intravenous Cyclophosphamide In The Induction Treatment Of Lupus Nephritis: A Metaanalysis Of Randomized Controlled Trials, Jin Deng, Lei Luo, Lin Zhu, Huan Xie, Hong-Ping Xie
Multitarget Therapy Versus Intravenous Cyclophosphamide In The Induction Treatment Of Lupus Nephritis: A Metaanalysis Of Randomized Controlled Trials, Jin Deng, Lei Luo, Lin Zhu, Huan Xie, Hong-Ping Xie
Turkish Journal of Medical Sciences
Background/aim: Multitarget therapy for lupus nephritis (LN) remains in its exploratory phrase and the recent evidence is insufficient. This study aimed to evaluate the efficacy and safety of mycophenolate mofetil (MMF), tacrolimus (TAC), and steroids (multitarget therapy) versus intravenous cyclophosphamide (IVC) and steroids in induction treatment of LN. Materials and methods: We searched for randomized controlled trials of MMF plus TAC versus IVC in LN using PubMed, EMBASE, the Cochrane Central Register of Controlled Trials, the China Biology Medicine Database, and the China National Knowledge Infrastructure Database. We assessed the retrieved citations and selected studies according to predefined inclusion and …
Paricalcitol Inhibits The Wnt/Beta-Catenin Signaling Pathway And Amelioratesexperimentally Induced Arthritis, Servet Yolbaş, Ahmet Yildirim, Ahmet Tektemur, Zulfi̇naz Betül Çeli̇k, Ebru Önalan, İbrahi̇m Hani̇fi̇ Özercan, Mehmet Mustafa Akin, Süleyman Serdar Koca
Paricalcitol Inhibits The Wnt/Beta-Catenin Signaling Pathway And Amelioratesexperimentally Induced Arthritis, Servet Yolbaş, Ahmet Yildirim, Ahmet Tektemur, Zulfi̇naz Betül Çeli̇k, Ebru Önalan, İbrahi̇m Hani̇fi̇ Özercan, Mehmet Mustafa Akin, Süleyman Serdar Koca
Turkish Journal of Medical Sciences
Background/aim: The Wnt/ß-catenin pathway has important biological activities, including the differentiation of cells and joint formations. The aim of our study was to determine the effect of paricalcitol on experimentally induced arthritis. Materials and methods: Type II collagen combined with Freund's adjuvant was applied to induce arthritis in Wistar albino female rats. Paricalcitol (0.3 μg/kg daily) was subcutaneously injected starting 1 day after collagen applications (prophylactic group) or 1 day after the onset of arthritis (therapeutic group), until day 29. Results: The 29th day arthritis scores were lower compared to the 13th day scores in the paricalcitol groups (P < 0.05), while they were higher in the arthritis group (P < 0.05). Marked cartilage-bone destruction and extensive perisynovial inflammation were detected in the arthritis group. Decreased cartilage-bone destruction and perisynovial inflammation in the paws were observed in the paricalcitol groups. The tissue mRNA levels of DKK1, Wnt5a, and axin-2 were higher in the arthritis group than in the control group. In the paricalcitol groups, mRNA expressions were lower than in the arthritis group. Conclusion: The present study shows that the Wnt/ß-catenin signaling pathway is active in arthritis. Moreover, paricalcitol ameliorates arthritis via inhibiting the Wnt/ß-catenin pathway. Paricalcitol and the Wnt/ß-catenin pathway are candidates for research in human rheumatoid arthritis.
The Comparative Effects Of Esmolol And Amiodarone On Isolated Coronary Arterybypass Grafts, Demet Özkaramanli Gür, Özcan Gür, Selami̇ Gürkan
The Comparative Effects Of Esmolol And Amiodarone On Isolated Coronary Arterybypass Grafts, Demet Özkaramanli Gür, Özcan Gür, Selami̇ Gürkan
Turkish Journal of Medical Sciences
Background/aim: Esmolol and amiodarone are two most commonly used antiarrhythmic drugs in coronary artery bypass grafting (CABG) surgery. Nevertheless, blockade of beta-2 receptors by increasing doses raise concerns about possible vasospasms. We studied the vasoactive effects of amiodarone and esmolol on left internal mammary artery (LIMA), radial artery (RA), and saphenous vein (SV) grafts. Materials and methods: After determining the presence of functional smooth muscle and endothelial layers, the responses of submaximally preconstricted graft samples were recorded in a tissue bath system. A total of 96 graft samples from 40 patients were used: 16 LIMA, 16 RA, and 16 SV …
Identification Of Candida Species By Restriction Enzyme Analysis, Reyhan Yi̇ş, Mi̇ne Doluca
Identification Of Candida Species By Restriction Enzyme Analysis, Reyhan Yi̇ş, Mi̇ne Doluca
Turkish Journal of Medical Sciences
Background/aim: The identification of Candida species isolated from clinical specimens provides information about antifungal susceptibility and sheds light on the choice of empirical treatment. In the present study, restriction enzyme analysis of C. albicans and non-albicans Candida species previously identified by conventional methods was done to evaluate the utility of restriction enzyme analysis for more rapid and reliable identification of Candida species. Materials and methods: A total of 146 Candida strains isolated from various clinical specimens and ATCC strains were included. PCR products were digested with MwoI for all species and with BslI for C. parapsilosis and C. tropicalis strains. …
Emerging Biomarker For Predicting Acute Kidney Injuryafter Cardiac Surgery: Cystatin C, Onur Saydam, Ercan Türkmen, Oytun Portakal Akçi̇n, Mustafa Arici, Riza Doğan, Meti̇n Demi̇rci̇n, İlhan Paşaoğlu, Mustafa Yilmaz
Emerging Biomarker For Predicting Acute Kidney Injuryafter Cardiac Surgery: Cystatin C, Onur Saydam, Ercan Türkmen, Oytun Portakal Akçi̇n, Mustafa Arici, Riza Doğan, Meti̇n Demi̇rci̇n, İlhan Paşaoğlu, Mustafa Yilmaz
Turkish Journal of Medical Sciences
Background/aim: Cardiopulmonary bypass (CPB)-associated acute kidney injury (AKI) is a common situation and rapid diagnosis and risk classification are important in the prevention and management of AKI. Changes in serum creatinine (SCr) levels in the current consensus criteria do not allow clinicians to diagnose CPB-associated AKI until 48 h after surgery. Materials and methods: We conducted a prospective single center study involving 57 patients who underwent cardiac surgery with CBP to compare serum beta-trace protein (BTP), neutrophil gelatinase-associated lipocalin-2 (NGAL), and cystatin C (CysC) levels with SCr for early diagnosis of CPB associated AKI. We defined AKI according to KDIGO …
Molecular Characterization Of The Nematode Heterakis Gallinarum (Ascaridida: Heterakidae) Infecting Domestic Chickens (Gallus Gallus Domesticus) In Tunisia, Nabil Amor, Sarra Farjallah, Osama Badri Mohammed, Abdulaziz Alagaili, Lilia Bahri
Molecular Characterization Of The Nematode Heterakis Gallinarum (Ascaridida: Heterakidae) Infecting Domestic Chickens (Gallus Gallus Domesticus) In Tunisia, Nabil Amor, Sarra Farjallah, Osama Badri Mohammed, Abdulaziz Alagaili, Lilia Bahri
Turkish Journal of Veterinary & Animal Sciences
Heterakis gallinarum is one of the most recurrently diagnosed nematodes within the gastrointestinal tract of galliform birds. In the present study, we investigated the genetic diversity of 96 H. gallinarum collected from free-range chickens from different localities in Tunisia. We assessed phylogeny and genetic variability using the internal transcribed spacers (ITS) of the nuclear ribosomal DNA and the mitochondrial cytochrome c oxidase subunit I gene. Haplotype and nucleotide diversities indicate that H. gallinarum is a species with extremely low genetic diversity. Based on the networks and phylogenetic trees, there was strong support for the absence of significant geographical structuring among …
The Role Of A Novel Wolbachia (Rickettsiales: Anaplasmataceae) Synthetic Peptide, Wolfar, In Regulating Prostaglandin Levels In The Hemolymph Of Acheta Domesticus (Orthoptera: Gryllidae), Muhamad Azmi Mohammed, Ameyra Aman Zuki, Nurul Othman Wahida, Yohsuke Tagami, Salmah Yaakop
The Role Of A Novel Wolbachia (Rickettsiales: Anaplasmataceae) Synthetic Peptide, Wolfar, In Regulating Prostaglandin Levels In The Hemolymph Of Acheta Domesticus (Orthoptera: Gryllidae), Muhamad Azmi Mohammed, Ameyra Aman Zuki, Nurul Othman Wahida, Yohsuke Tagami, Salmah Yaakop
Turkish Journal of Zoology
Prostaglandins and other eicosanoids are known as regulating agents for cellular immune responses to pathogen threats in an insect?s hemolymph. A novel synthetic peptide, WolFar, was customized from a conserved region of the Wolbachia surface protein (WSP), isolated from an economically important endoparasitoid species, Fopius arisanus. WolFar consists of nine amino acids (SYY VRL QYN) and was tested on the house cricket, Acheta domesticus. Three concentrations of peptides, 0.83 mmol/L (100%), 0.63 mmol/L (75%), and 0.42 mmol/L (50%), were injected and observed for 72 h. The regulation of prostaglandin E2 (PGE2) in the hemolymph of A. domesticus was determined using …
Diel And Seasonal Activity Of Ground Dwelling Spiders (Araneae) In A Sandy Grassland Habitat, Anna Król, Izabela Hajdamowicz, Cezary Tkaczuk
Diel And Seasonal Activity Of Ground Dwelling Spiders (Araneae) In A Sandy Grassland Habitat, Anna Król, Izabela Hajdamowicz, Cezary Tkaczuk
Turkish Journal of Zoology
The paper concerns the diel and seasonal activity of ground dwelling spiders on a sandy grassland in the Bug River Valley in East-Central Poland. The spiders were captured using pitfall traps in 2009 and 2010 from May to July. The material was collected one day a week, day and night. Traps were checked every 3 h, eight times a day. It was found that for spiders with larger bodies, from the families Lycosidae and Philodromidae, the peak of their activity was in the afternoon, and smaller spiders belonging to the families Linyphiidae and Tetragnathidae showed the greatest activity in the …
A New Record Of Three-Band Garden Slug Ambigolimax Valentianus (A. Férussac, 1822) (Gastropoda: Limacidae) From Turkey, İhsan Eki̇n, Ridvan Şeşen
A New Record Of Three-Band Garden Slug Ambigolimax Valentianus (A. Férussac, 1822) (Gastropoda: Limacidae) From Turkey, İhsan Eki̇n, Ridvan Şeşen
Turkish Journal of Zoology
Ambigolimax valentianus (A. Férussac, 1822), the three-band garden slug, is originally native to the Iberian Peninsula (Spain, Portugal, and the Balearic Islands); however, it has been spread by human activities to many other parts of the world. There is no distributional record of the slug in Turkey to date. The species was recorded for the first time in Turkey during a biological survey carried out in the accommodation area of Dicle University (Diyarbakır) in October 2017. Some of the slugs were transferred to the laboratory for their morphological determination and dissection. Notably, more than 50 species of slugs dwell on …
New Species And New Record Of Chelonini (Hymenoptera: Braconidae) From Western Iran, Alireza Rajabi Mazhar, Shila Goldasteh, Samira Farahani, Cornelis Van Achterberg
New Species And New Record Of Chelonini (Hymenoptera: Braconidae) From Western Iran, Alireza Rajabi Mazhar, Shila Goldasteh, Samira Farahani, Cornelis Van Achterberg
Turkish Journal of Zoology
In 2015 and 2016, the occurrence of the tribe Chelonini (Braconidae, Cheloninae) in the province of Hamadan (western Iran) was surveyed using malaise traps. In total, 12 species were discovered. Chelonus (C.) olgae Kokujev, 1895 is new to the fauna of Iran and one species, Chelonus (Microchelonus) subpamiricus Farahani & van Achterberg sp. nov., is new to science. The diagnostic characters and supplementary illustrations of the newly recorded species are provided.
Sexual Size Dimorphism And Sex Determination By External Measurements In The Redshank Tringa Totanus, Wlodzimierz Meissner, Pavel Pinchuk, Natalia Karlionova, Izabela Fischer, Lucyna Pilacka
Sexual Size Dimorphism And Sex Determination By External Measurements In The Redshank Tringa Totanus, Wlodzimierz Meissner, Pavel Pinchuk, Natalia Karlionova, Izabela Fischer, Lucyna Pilacka
Turkish Journal of Zoology
The Redshank is a wader species that shows no sexual dimorphism in plumage, but some dimorphism in size. To propose a method for sexing birds of this species by linear measurements, a discriminant function analysis was applied to a set of morphometric traits in birds captured during the spring migration in southern Belarus. In total, 113 males and 75 females were measured and sexed molecularly. On average, females were larger in all measurements than males. The most sexually dimorphic trait was wing length, which was included in the discriminant function analysis. Jackknife cross-validation showed that the provided equation allowed the …
Investigations On The Cannibalistic Behavior Of Ladybird Beetlecoccinella Septempunctata L. (Coleoptera: Coccinellidae) Under Laboratory Conditions, Muhammad Hamayoon Khan, Zeynep Yoldaş
Investigations On The Cannibalistic Behavior Of Ladybird Beetlecoccinella Septempunctata L. (Coleoptera: Coccinellidae) Under Laboratory Conditions, Muhammad Hamayoon Khan, Zeynep Yoldaş
Turkish Journal of Zoology
Cannibalism or intraspecific predation, where one species feeds on individuals of its own species, is a widespread phenomenon in most aphidophagous coccinellids. Laboratory studies were conducted on the cannibalistic behavior of various developmental stages of Coccinella septempunctata L. (Coleoptera: Coccinellidae) in the presence and absence of natural food, Acyrthosiphon pisum (Harris) (Hemiptera: Aphididae). In both the presence and absence of aphids, the eggs and 1st and 2nd instars of C. septempunctata were cannibalized by the adults, and the level was inversely related to the availability of aphids. The same was also true for cannibalism of eggs by larvae and within …
Fractal Analysis Of Structural Differences Of Otolith Microrelief In Closely Related And Distant Baikal Ichthyotaxa, Marina Tyagun, Aleksey Golovko
Fractal Analysis Of Structural Differences Of Otolith Microrelief In Closely Related And Distant Baikal Ichthyotaxa, Marina Tyagun, Aleksey Golovko
Turkish Journal of Zoology
Fractal analysis helped find differences in species in the organisation of fish otolith crystalline surfaces in 2 closely related and 2 distant species. To determine regularities of this organisation, we used the microcanonical method of multifractal spectra. It was revealed that the differences of multifractal spectra were more significant for longer distances of taxonomic divergence.
Habitat Structure And Host Plant Specialization Drive Taxonomic Andfunctional Composition Of Heteroptera In Postfire Successional Habitats, Eduardo Mateos, Marta Goula, Teresa Sauras, Xavier Santos
Habitat Structure And Host Plant Specialization Drive Taxonomic Andfunctional Composition Of Heteroptera In Postfire Successional Habitats, Eduardo Mateos, Marta Goula, Teresa Sauras, Xavier Santos
Turkish Journal of Zoology
Changes in habitat structure are the main driving forces for responses of animal assemblages to fire. According to the disturbance theory, generalist species are expected to outperform specialists in variable environments. Thus, we hypothesized that omnivorous and polyphagous species will become more abundant in unstable postfire successional vegetation, whereas monophagous (specialists), due to their strong dependence on host plants, are expected to respond according to the responses of plant hosts. We compared the responses of true bug (Heteroptera) assemblages in stable (unburnt) versus unstable (postfire successional) environments as this group shows a high diversity of feeding strategies. Redundancy analysis fitted …
The Invasive Ameiurus Nebulosus (Lesueur, 1819) As A Permanent Part Of The Fish Fauna In Selected Reservoirs In Central Europe: Long-Term Study Of Three Shallow Lakes, Jacek Rechulicz, Wojciech Plaska
The Invasive Ameiurus Nebulosus (Lesueur, 1819) As A Permanent Part Of The Fish Fauna In Selected Reservoirs In Central Europe: Long-Term Study Of Three Shallow Lakes, Jacek Rechulicz, Wojciech Plaska
Turkish Journal of Zoology
The invasive brown bullhead (Ameiurus nebulosus (Lesueur, 1918)) has been present in Europe since the late 19th century, but there is still a lack of reliable information about its distribution in Europe and the condition of its population. A long-term study (from 2000 to 2011) in three shallow lakes in Central Europe (eastern Poland) was carried out to determine the occurrence of the brown bullhead and its participation in the fish community. The brown bullhead was present in almost all the sampling fishing in all the lakes studied (C$_{i}$ = 72%-82%). Its mean abundance and share in the fish biomass …
Three New Records From Phylinae (Hemiptera: Heteroptera: Miridae) For The Turkish Fauna, Gülten Yazici, Erol Yildirim
Three New Records From Phylinae (Hemiptera: Heteroptera: Miridae) For The Turkish Fauna, Gülten Yazici, Erol Yildirim
Turkish Journal of Zoology
This study was conducted in the Erzurum province of Turkey during 2009-2014. The species Criocoris crassicornis (Hahn, 1834), Europiella artemisiae (Becker, 1864), and Paredrocoris pectoralis Reuter, 1878 were recorded for the first time from Turkey. The important taxonomic characters are described and photographs or illustrations are provided.
Investigation Of Syphilis Coinfection And Performance Of The Architect Syphilis Tp Elisa Screening Test In Hiv Positive Patients, Cemi̇le Sönmez, Tüli̇n Demi̇r, Fi̇gen Sezen, Selçuk Kiliç
Investigation Of Syphilis Coinfection And Performance Of The Architect Syphilis Tp Elisa Screening Test In Hiv Positive Patients, Cemi̇le Sönmez, Tüli̇n Demi̇r, Fi̇gen Sezen, Selçuk Kiliç
Turkish Journal of Medical Sciences
Background/aim: Limited data on syphilis coinfection in human immunodeficiency virus (HIV) positive cases exist in Turkey. Our aim is to investigate syphilis coinfection and to evaluate the compatibility of the screening Architect Syphilis Tp ELISA with the fluorescent treponemal antibody absorption (FTA-abs) confirmation test in HIV positive cases. Materials and methods: Totally 519 HIV positive patients were included in the study. Enzyme linked fluorescent assay (ELFA) was used as a screening test and positive samples were confirmed by line immunassay (LIA). In order to discriminate acute HIV infection and false ELISA positivity, HIV-1 RNA PCR was performed in ELFA positive …
Losartan Inhibits Egfr Transactivation In Vascular Smooth Muscle Cells, Mustafa Kirça, Akin Yeşi̇lkaya
Losartan Inhibits Egfr Transactivation In Vascular Smooth Muscle Cells, Mustafa Kirça, Akin Yeşi̇lkaya
Turkish Journal of Medical Sciences
Background/aim: Angiotensin II (Ang II)-induced molecular signaling pathways play a significant role in the progression of cardiovascular diseases, including hypertension and atherosclerosis. In addition to the well-known effects of Ang II, it may activate epidermal growth factor receptor (EGFR) in a process known as transactivation, which contributes to vascular pathologies. The aim of this study was to determine whether losartan could reduce EGFR transactivation induced by Ang II. Additionally, we evaluated the roles of heparin-binding epidermal-like growth factor (HB-EGF) and matrix metalloproteinases (MMPs) in Ang II-induced EGFR transactivation. Materials and methods: Vascular smooth muscle cells were isolated from a rat …
Investigation Of The Effect Of Combined Use Of Alloplastic-Based Tricalcium Phosphate Bone Graft And Antihemorrhagic Plant Extract (Abs) On Bone Regeneration In Surgically Induced Bone Defects In Nondiabetic Rats: An Experimental Animal Study, Abdulsamet Tani̇k, Arzum Güler Doğru, Veysi̇ Akpolat, Fi̇li̇z Acun Kaya, Ebru Saribaş, Mehmet Gül, Sevgi̇ İrtegün, Engi̇n Deveci̇
Investigation Of The Effect Of Combined Use Of Alloplastic-Based Tricalcium Phosphate Bone Graft And Antihemorrhagic Plant Extract (Abs) On Bone Regeneration In Surgically Induced Bone Defects In Nondiabetic Rats: An Experimental Animal Study, Abdulsamet Tani̇k, Arzum Güler Doğru, Veysi̇ Akpolat, Fi̇li̇z Acun Kaya, Ebru Saribaş, Mehmet Gül, Sevgi̇ İrtegün, Engi̇n Deveci̇
Turkish Journal of Medical Sciences
Background/aim: In this experimental study, we aimed to evaluate the late period effects of the combination of Ankaferd Blood Stopper (ABS), which has bone wound healing effects, and ß-tricalcium phosphate (TCP) on the regeneration of bone tissue through histopathological, immunohistochemical, and radiological (dual energy X-ray absorptiometry - DEXA) methods in nondiabetic rats. Materials and methods: Sixty-four Wistar albino male rats were used. In the calvaria of the rats, a bone defect 7.0 mm in diameter was created. These rats were divided into 4 different groups. Group 1 was the control group without any treatment, a 0.125 mL B-TCP graft was …
A New Ostracoda (Crustacea) Genus, Comalcandona Gen. Nov., From Texas, Usa, Okan Külköylüoğlu, Randy Gibson
A New Ostracoda (Crustacea) Genus, Comalcandona Gen. Nov., From Texas, Usa, Okan Külköylüoğlu, Randy Gibson
Turkish Journal of Zoology
A new freshwater ostracod genus, Comalcandona gen. nov., and its type species (Comalcandona tressleri sp. nov.) are described from John Knox Ranch, Comal County, Texas, USA. The new genus differs from the related genera in the presence of the shallow pits on the trapezoidal shape of the carapace and presence of one well-developed anterior claw (posterior claw and both anterior and posterior setae are absent) on the uropod, a diagnostic character. Differences in the structure of the hemipenes, length and numbers of setae on the extremities, and shape of some other soft body parts also separate this genus from the …
Tardigrada Of Bory Tucholskie National Park, Zaborski Landscape Park, And Their Surroundings (Pomerania Province, Poland), Lukasz Kaczmarek, Jakub Kosicki, Milena Roszkowska
Tardigrada Of Bory Tucholskie National Park, Zaborski Landscape Park, And Their Surroundings (Pomerania Province, Poland), Lukasz Kaczmarek, Jakub Kosicki, Milena Roszkowska
Turkish Journal of Zoology
In this paper, samples of mosses and lichens collected from Bory Tucholskie National Park, Zaborski Landscape Park, and their surroundings (Pomerania Province, northern Poland) were studied for water bears (Tardigrada). In total, 38 tardigrade taxa were identified and six of them (Hypsibius cf. allisoni, Hyp. scabropygus, Macrobiotus sottilei, Milnesium beasleyi, Mil. dornensis, and Mil. granulatum) are new records for the Polish fauna. Eighteen taxa (only 14 identified to the species level) were found in Bory Tucholskie National Park, whereas in Zaborski Landscape Park this number was much larger, i.e. 28 taxa (including 22 identified to the species level), as well …
Feeding Dynamics And Performance Of Beetal Does In Relation To Body Condition Score At The Time Of Mating, Arpan Sharma, Sandeep Kaswan, S. Siva Kumar, Jaspal Singh Lamba
Feeding Dynamics And Performance Of Beetal Does In Relation To Body Condition Score At The Time Of Mating, Arpan Sharma, Sandeep Kaswan, S. Siva Kumar, Jaspal Singh Lamba
Turkish Journal of Veterinary & Animal Sciences
The body condition of does at the time of mating may affect feeding patterns and production performance during forthcoming lactation. For investigation, 40 Beetal does available for breeding were utilized, and their body condition score (BCS) was estimated using the visual-cum-palpation method with a 9-point scale (scale of 1=5 with increments of 0.5 point). The available goats were divided into 3 groups: higher BCS (T$_{≥3.0}$; n =11), moderate BCS (T$_{2.5}$; n = 8), and lower BCS (T$_{≤2.0}$; n = 21) and maintained in 2 random groups (20 each). Beetal goats with higher BCS at breeding time spent significantly (P < 0.01) more time feeding comfortably and less time feeding with difficulty than moderate and lower BCS goats. T2.5 and T$_{≤2.0}$ goats struggled (displacement and pushing) more at feeders, which included T$_{≤2.0}$ goats eating from the ground for more time (P < 0.01) than the other groups. T$_{≥3.0}$ goats had more agonistic interactions (threatening and hitting) toward moderate and lower BCS goats at feeders. Goats with higher BCS at mating had significantly (P < 0.05) higher milk yield during subsequent lactation; however, the composition of the milk did not differ among the groups. Mean disease incidence rate and number of days of disease per goat were significantly (P < 0.01) lesser in the T$_{≥3.0}$ group than other groups. It was concluded that Beetal goats should not have less than 3.0 BCS at the time of mating for better performance and health status.
Impacts Of Environmental Factors On Zooplankton Taxonomic Diversity In Coastal Lagoons In Turkey, Nuray Akbulut, Ülkü Ni̇han Tavşanoğlu
Impacts Of Environmental Factors On Zooplankton Taxonomic Diversity In Coastal Lagoons In Turkey, Nuray Akbulut, Ülkü Ni̇han Tavşanoğlu
Turkish Journal of Zoology
Lagoons are valuable ecosystems providing various services, such as fishing, recreational activities, and land reclamation, as well as hosting high biodiversity. Although lagoons in Turkey cover a coastal area of more than 36,000 ha, few studies of them have been conducted. Therefore, two lagoons (Dalyan and Arapçiftliği) located on the coast of the Sea of Marmara in the Kocaçay Delta, which is under intense anthropogenic pressure, were investigated between November 2013 and March 2015 to examine the effects of environmental factors on taxonomic diversity. In addition, ongoing high nutrient flow from the Karacabey region triggers eutrophication in the lagoons, thus …
Morphological Variation Of Pumpkinseed (Lepomis Gibbosus) With Emphasis On Allometry, Fati̇h Mangit, Mustafa Korkmaz, Sedat Vahdet Yerli̇
Morphological Variation Of Pumpkinseed (Lepomis Gibbosus) With Emphasis On Allometry, Fati̇h Mangit, Mustafa Korkmaz, Sedat Vahdet Yerli̇
Turkish Journal of Zoology
Pumpkinseed(Lepomis gibbosus)is an exotic fish species widely distributed in Europe and it has expanded its distribution area in Turkey since its first report in 1982. It is well known that invasive species like L. gibbosus adapt to introduced habitats relatively well. In order to evaluate morphological variation within this invasive species, sampling was carried out in June 2012 and May 2013 in the Aegean and Thrace regions, respectively. Body-form variability in sampled populations of L. gibbosus was investigated using landmark-based geometric morphometrics. L. gibbosus showed significant geographic- and habitat-based differences with and without allometric standardization. However, outcomes of these results …