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Full-Text Articles in Entire DC Network
B Mode Ultrasonography And Elastography In The Evaluation Of The Pectineus Muscle Indogs With Hip Dysplasia, Pedro Paulo Rossignoli, Marcus Antônio Rossi Feliciano, Bruno Watanabe Minto, Marjury Cristina Maronezi, Ricardo Andres Ramirez Uscategui, Cléber Kazuo Ido, Daniele Santos Rolemberg, Luís Guilherme De Faria, Igor Cezar Kniphoff Da Cruz, Luiz Paulo Nogueira Aires
B Mode Ultrasonography And Elastography In The Evaluation Of The Pectineus Muscle Indogs With Hip Dysplasia, Pedro Paulo Rossignoli, Marcus Antônio Rossi Feliciano, Bruno Watanabe Minto, Marjury Cristina Maronezi, Ricardo Andres Ramirez Uscategui, Cléber Kazuo Ido, Daniele Santos Rolemberg, Luís Guilherme De Faria, Igor Cezar Kniphoff Da Cruz, Luiz Paulo Nogueira Aires
Turkish Journal of Veterinary & Animal Sciences
The goal of this study was to describe and compare B mode and elastographic characteristics of the pectineus muscle of healthy dogs with dysplastic dogs. Thirty-one dogs (62 limbs) with hip dysplasia and 17 nondysplastic dogs (34 limbs) were evaluated. The hip dysplasia score was defined according to the Fédération Cynologique Internationale. Using B mode, echotexture and echogenicity of different regions of the pectineus muscle were evaluated. By means of ARFI elastography, qualitative (elastogram) and quantitative (shear wave velocity) tissue stiffness was assessed. B mode findings demonstrated a hyperechoic and heterogeneous pattern of the pectineus tissue in dogs with hip …
Antibiotic Susceptibility And Phylogenetic Analyses For The Origins And Serotypes Of Listeria Monocytogenes Strains Isolated From Ice Cream And Cream Cakes, Orkun Babacan
Turkish Journal of Veterinary & Animal Sciences
Listeria monocytogenes is a zoonotic bacterium which also infects humans. The aim of this study was to isolate this organism from cream cakes and ice cream and obtain 16S rRNA and hlyA gene sequences from isolates in order to perform phylogenetic analyses. Serotypes and antibiotic susceptibility were also determined. The cream cake and ice cream samples were examined for L. monocytogenes according to ISO 11290-1 and using the mini Vidas LMO 2 kit procedure. Antibiotic susceptibilities were investigated using the disc diffusion method according to the European Committee on Antimicrobial Susceptibility Testing (EUCAST) and the Clinical and Laboratory Standards Institute …
Organochlorine Pesticide Residues In Feathers Of Four Bird Species From Westernpart Of Turkey, Kalender Arikan, Sali̇h Levent Turan
Organochlorine Pesticide Residues In Feathers Of Four Bird Species From Westernpart Of Turkey, Kalender Arikan, Sali̇h Levent Turan
Turkish Journal of Zoology
The use of organochlorine pesticides (OCPs) has decreased considerably worldwide; they have been banned in most countries due to adverse impacts on wildlife. The purpose of the study was to investigate OCP residue levels in wild birds from Aegean, Marmara, Mediterranean, and Central Anatolia geographical regions of Turkey. Feather samples (n = 80) of four bird species in four regions were collected from anthropogenically dead birds such as roadkill and wind turbine collision. Feather samples were analysed using GC/MS and scanned for 23 pesticide congeners. Analysis results showed dichlorodiphenyltrichloroethane (DDT), hexachlorocyclopentadiene (HCCPD), and their derivatives were present in almost all …
Diurnal Time-Activity Budget And Foraging Techniques Of Red-Crested Pochards(Netta Rufina) Wintering At The Wetlands Of West Bengal, India, Arkajyoti Mukherjee, Sudin Pal, Subhra Kumar Mukhopadhyay
Diurnal Time-Activity Budget And Foraging Techniques Of Red-Crested Pochards(Netta Rufina) Wintering At The Wetlands Of West Bengal, India, Arkajyoti Mukherjee, Sudin Pal, Subhra Kumar Mukhopadhyay
Turkish Journal of Zoology
The present study aimed at recording the time-activity budget and feeding techniques of red-crested pochards (RCPs) to test the hypotheses that feeding techniques were influenced by the sexes and contrasting physical conditions of the habitat. The timeactivity budget was quantified using the scanned sample approach. In this study, the mean sex ratio of the RCPs was recorded as 0.655. Dominant behavior was sleeping or resting (42.8% in February to 47.0% in January), followed by swimming (27.1% in February to 29.8% in December), feeding (10.9% in December to 16.6% in February), and preening (9.0% in January to 12.1% in February). During …
The Spider Losdolobus Nelsoni Pompozzi, 2015 - The First Report Of The Familyorsolobidae In Uruguay (Araneae: Synspermiata), Luis Fernando García, Alvaro Laborda, Osvaldo Villarreal, Juan Burla, Enrique Castiglioni
The Spider Losdolobus Nelsoni Pompozzi, 2015 - The First Report Of The Familyorsolobidae In Uruguay (Araneae: Synspermiata), Luis Fernando García, Alvaro Laborda, Osvaldo Villarreal, Juan Burla, Enrique Castiglioni
Turkish Journal of Zoology
The family Orsolobidae Cooke, 1965, is newly recorded for Uruguay, with the first record of Losdolobus nelson Pompozzi, 2015, a recently described species that is endemic to the Buenos Aires Province, Argentina, and herein recorded in the Rocha and Montevideo departments. The biogeographic implications of this record are commented on and some data on the phenology of the species are presented.
Effects Of Carvacrol Administration On Motor Function Following Spinal Ischemia Andreperfusion, Ayhan Çeti̇nkaya, Çağri Çamsari
Effects Of Carvacrol Administration On Motor Function Following Spinal Ischemia Andreperfusion, Ayhan Çeti̇nkaya, Çağri Çamsari
Turkish Journal of Zoology
The sensitivity of the medulla spinalis to ischemia and reperfusion has been shown in previous in vitro and in vivo studies. However, less is known about the effects of carvacrol administration following ischemia and reperfusion. It was hypothesized that carvacrol might have protective effects on motor neuron functionunder ischemia- and reperfusion-induced oxidative stress. A total of 24 adult Wistar rats were divided into three groups: group I (control group; n = 8), group II (spinal ischemia and reperfusion group; n = 8), and group III (spinal ischemia and reperfusion + carvacrol group; n = 8). Ischemia and reperfusion were performed …
Genetic Diversity Of Codling Moth Cydia Pomonella L. (Lepidoptera: Tortricidae)Populations In Turkey, Akin Kuyulu, Hani̇fe Genç
Genetic Diversity Of Codling Moth Cydia Pomonella L. (Lepidoptera: Tortricidae)Populations In Turkey, Akin Kuyulu, Hani̇fe Genç
Turkish Journal of Zoology
The codling moth (Cydia pomonella L., Lepidoptera: Tortricidae) is a well-known pest worldwide and was first reported in 1952 in Turkey. It is traditionally controlled with several pesticide applications during each apple production season. The genetic diversity of codling moths was investigated in this study, based on the partial mitochondrial cytochrome oxidase subunite I gene. Twenty-two haplotypes from 9 populations were studied. The results showed an average haplotype and nucleotide diversity of 0.835 and 0.571, respectively. Phylogenetic analyses were indicated for 2 major clades using the maximum likelihood method. Median Joining Network analysis revealed that the 2 major clades are …
Order Diptera As A Model In The Studies Of Insect Immunity: A Review, Danail Ilchev Takov, Peter Vladislavov Ostoich, Andrey Ivanov Tchorbanov, Daniela Kirilova Pilarska
Order Diptera As A Model In The Studies Of Insect Immunity: A Review, Danail Ilchev Takov, Peter Vladislavov Ostoich, Andrey Ivanov Tchorbanov, Daniela Kirilova Pilarska
Turkish Journal of Zoology
Order Diptera is the most important group of animals when it comes to insect immunity research. The largest share of experimental data in the group falls on the genus Drosophila - a model species with a number of advantages. Other crucial representatives are those of the mosquito group, as they are vectors of a number of infectious diseases infecting higher vertebrates and humans. As representatives of the genera, Anopheles, Aedes and Culex are very significant model organisms. In total, more than 40 dipteran species are being actively studied as models in various aspects related to immunity. Together with the representatives …
Biochemical And Physiological Responses Of Nili-Ravi Buffalo (Bubalus Bubalis) To Heatstress, Umair Younas, Muhammad Abdullah, Jalees Ahmed Bhatti, Nisar Ahmed, Faisal Shahzad, Musadiq Idris, Sana Tehseen, Muhammad Junaid, Saima Tehseen, Saeed Ahmed
Biochemical And Physiological Responses Of Nili-Ravi Buffalo (Bubalus Bubalis) To Heatstress, Umair Younas, Muhammad Abdullah, Jalees Ahmed Bhatti, Nisar Ahmed, Faisal Shahzad, Musadiq Idris, Sana Tehseen, Muhammad Junaid, Saima Tehseen, Saeed Ahmed
Turkish Journal of Veterinary & Animal Sciences
The present study was designed with an objective to evaluate the impact of various strategies to alleviate heat stress on certain physiological attributes viz. respiratory rate (RT), body surface temperature (BST), pulse rate (PR), and respiratory rate (RR); biochemical attributes viz. glucose, total protein (TP), and cholesterol; and endocrinological parameters (tri-iodothyronine and tetraiodothyronine) of the Nili-Ravi buffaloes during early summer season. Lactating Nili-Ravi buffaloes (n = 20) with close production and parity stage were divided into four treatment groups as group A (control group under roof shades only), B (experimental group under roof shades with antistress supplementation), C (experimental group …
Light And Scanning Electron Microscopic Examination Of The Saanen Goat Heart, Sedef Selvi̇ler Si̇zer, Yonca Beti̇l Kabak, Murat Kabak
Light And Scanning Electron Microscopic Examination Of The Saanen Goat Heart, Sedef Selvi̇ler Si̇zer, Yonca Beti̇l Kabak, Murat Kabak
Turkish Journal of Veterinary & Animal Sciences
It is important to know the morphological structure of the heart, which is a vital organ of the body, in detail. For this reason, we aimed to examine the morphological structure of the Saanen goat heart using light and scanning electron microscopy (SEM). A total of thirteen Saanen goat hearts were used in the study. To demonstrate the histological structure of the heart, samples taken from 9 hearts were fixed in 10% formaldehyde solution and blocked in paraffin after routine histological procedures. Histological staining was performed on the sections taken from the blocks. Four hearts were fixed in a 2.5% …
Prevalence Of Ectoparasites On A Stray Cat Population From "Town Of Knowledge" Kotasamarahan, Sarawak, Malaysian Borneo, Naim Che Kamaruddin, Madinah Adrus, Wan Nurainie Wan Ismail
Prevalence Of Ectoparasites On A Stray Cat Population From "Town Of Knowledge" Kotasamarahan, Sarawak, Malaysian Borneo, Naim Che Kamaruddin, Madinah Adrus, Wan Nurainie Wan Ismail
Turkish Journal of Veterinary & Animal Sciences
Stray cats survive on their own and scavenge the surrounding areas for food to survive. Their exploitation to investigate the prevalence of ectoparasites can be of great medical importance for humans as they harbour a variety of zoonotic pathogens. Therefore, a survey of ectoparasites on stray cats was carried out from November 2017 to March 2018 around the Town of Knowledge to determine the prevalence of ectoparasites in stray cats and their potential to threaten the public health by infesting stray cats around Kota Samarahan, Sarawak, Malaysian Borneo. A total of 150 individuals of stray cats have been examined for …
Effect Of Prebiotics On The Growth Performance, Haematological, Biochemical, Andhistological Parameters Of African Catfish (Clarias Gariepinus) In Recirculatingaquaculture System, Ercüment Genç, Münevver Ayçe Genç, Doğukan Kaya, Fai̇k Sertel Seçer, Abdolsaleh Qaranji̇ki̇, Derya Güroy
Effect Of Prebiotics On The Growth Performance, Haematological, Biochemical, Andhistological Parameters Of African Catfish (Clarias Gariepinus) In Recirculatingaquaculture System, Ercüment Genç, Münevver Ayçe Genç, Doğukan Kaya, Fai̇k Sertel Seçer, Abdolsaleh Qaranji̇ki̇, Derya Güroy
Turkish Journal of Veterinary & Animal Sciences
In this study, African catfish (Clarias gariepinus) was investigated under controlled conditions in recirculating aquaculture system (RAS). The experiment tested the effects of three different dietary prebiotics (FOS: fructooligosaccharide, GOS: galactooligosaccharide, and MOS: mannanoligosaccharide) in two levels (1 g/kg and 2 g/kg) and a control diet on the growth performance, survival rate, haematological and biochemical parameters, and small intestinal and liver histology of the African catfish. Better growth results were obtained in MOS (2 g/kg) supplementation, and there was a statistical difference (P < 0.05) between the MOS (2 g/kg) and the control group. Haematological parameters (erythrocyte sedimentation rate, red blood cell, white blood cell, lymphocyte, neutrophil, and glucose) were similar among all groups (P > 0.05) while some (alanine aminotransferase, aspartate aminotransferase enzymes, and monocyte) were significantly different (P < 0.05). The MOS (2 g/kg) group had longer villi length values than the control group. There was no difference among the groups in terms of small intestine histomorphology and liver tissues in fish. According to the results of this experiment, it can be said that MOS addition has a positive effect on growth parameters and could improve health conditions in Clarias gariepinus culture.
Contributions To The Systematics Of The Family Buprestidae (Coleoptera) By The Firstdescription Of Male External Genital Organ And Illustrations Of Six Species From Ankaraprovince, Ali̇ Kemal Kirçakci, Mahmut Kabalak
Contributions To The Systematics Of The Family Buprestidae (Coleoptera) By The Firstdescription Of Male External Genital Organ And Illustrations Of Six Species From Ankaraprovince, Ali̇ Kemal Kirçakci, Mahmut Kabalak
Turkish Journal of Zoology
The main aim of this study is to contribute to the systematics relating to the family Buprestidae, by studying the male external genital organs (aedeagi) of six species belonging to the genera Acmaeodera, Acmaeoderella, Anthaxia, Capnodis, and Perotis, none of which had been illustrated previously. Samples of these species were collected from the province of Ankara, Turkey, and the aedeagus of each was described and illustrated in detail for the first time. The findings were then compared with the current literature.
Ecotoxicological Investigation Of Cyanobacterial Crude Extracts Todaphnia Magna Under Subchronic Test Conditions, Tan Duc Nguyen, Xuan Quang Ngo, Thanh Luu Pham, Thanh Son Dao
Ecotoxicological Investigation Of Cyanobacterial Crude Extracts Todaphnia Magna Under Subchronic Test Conditions, Tan Duc Nguyen, Xuan Quang Ngo, Thanh Luu Pham, Thanh Son Dao
Turkish Journal of Zoology
Cyanobacterial blooms often consist of mixtures of microcystin-producing and microcystin-free species, and both can cause unpredictable effects on aquatic organisms. In this work, the subchronic effects of the cyanobacterial crude extracts (CCEs) from microcystin-producing and microcystin-free cyanobacteria with different microcystin concentrations (1, 10, and 50 μgL$^{-1}$)on Daphnia magna were investigated. The life-history trait responses of D. magna to CCEs were determined based on survival, reproduction, and somatic growth. In addition, the physiological response, represented by the feeding rate of D. magna on green algae (Scenedesmus sp.), after exposure to both types of crude extracts was estimated. Our results showed that …
Effect Of Chemical- And Toxin Binder-Treated Cotton Seed Cake On Milk Production, Milkcomposition, And Aflatoxin Concentration In Milk Of Nili Ravi Lactating Buffaloes, Murtaza Ali Tipu, Anjum Khalique, Muhammad Naveed Ul-Haque, Muhammad Qamer Shahid, Maqsood Akhtar, Mubashir Ilyas
Effect Of Chemical- And Toxin Binder-Treated Cotton Seed Cake On Milk Production, Milkcomposition, And Aflatoxin Concentration In Milk Of Nili Ravi Lactating Buffaloes, Murtaza Ali Tipu, Anjum Khalique, Muhammad Naveed Ul-Haque, Muhammad Qamer Shahid, Maqsood Akhtar, Mubashir Ilyas
Turkish Journal of Veterinary & Animal Sciences
Twelve multiparous Nili Ravi buffaloes were assigned to 1 of 3 treatments in a randomized, replicated 3 × 3 Latin square design to evaluate the effect of chemical (calcium propionate)- and toxin binder (sodium bentonite)-treated cotton seed cake (CSC) on milk yield and transfer of milk toxin (M1). Periods (20 days) were allocated for each treatment. In the 1st treatment (control), CSC with 100 μg/kg of aflatoxin B1 (AFB1) was fed to buffaloes. The 2nd and 3rd treatments were 0.5% calcium-propionate-treated CSC and 1.0% sodium-bentonite-treated CSC, respectively. Each group had 4 multiparous buffaloes. The buffaloes given 0.5% calcium propionate CSC …
The Effect Of Year, Month, Region, And Herd Size On Bulk Tank Somatic Cell And Standardplate Count, And The Determination Of Optimum Herd Size In The Intensive Holsteinfriesian Dairy Farms In The Turkish Republic Of Cyprus, Hati̇ce Di̇lek Arsoy
Turkish Journal of Veterinary & Animal Sciences
The objective of this study was to determine the effects of mount, year, region, and herd size on the bulk tank somatic cell count (SCC) and standard plate count (SPC) and total milk production of Holstein Friesian cows and to decide for optimum herd size in Northern Cyprus. The total number of cattle was 64,450 heads and the number of enterprises was 168 in 2016. The milk samples were collected once or twice a month from each herd. SCC and SPC were determined with the Fluoro-opto-electronic counter method. Herd sizes were described from small to extra-large enterprises for Northern Cyprus …
The Effects Of Season And Chick Sex On Certain Performance Parameters In Commercialturkey Farms In The Aegean Region, Gündüz İlsever, Pembe Di̇lara Keçi̇ci̇, Bülent Eki̇z
The Effects Of Season And Chick Sex On Certain Performance Parameters In Commercialturkey Farms In The Aegean Region, Gündüz İlsever, Pembe Di̇lara Keçi̇ci̇, Bülent Eki̇z
Turkish Journal of Veterinary & Animal Sciences
The aim of this study was to determine the effects of season and sex on the production efficiency of commercial turkey farms in the Aegean Region. The data of 1161 production periods (570 male and 591 female) on 139 turkey farms between 2008 and 2017 were analysed. Daily feed consumption, feed conservation ratio (FCR), average daily gain (ADG), performance index, and carcass weight (P < 0.001) were higher in males than females. While males and females had a similar mortality rate in the first week (P > 0.05), the mortality rate in the later stages was higher in males (P < 0.001). The mortality rate in the initial period was highest in production periods that began in winter and lowest in those that began in summer (P < 0.001). The total mortality rate was higher in the autumn group than in the spring and summer groups (P < 0.001). Rearing season × sex interaction had a significant influence on the performance characteristics investigated in the study, except for mortality rates and survival. In males, FCR was lower in the autumn and winter groups than that of the spring and summer groups (P < 0.05). The highest ADG values were observed in the summer group for males and in the winter group for females. The best performance index was in the summer group in males, and the lowest performance index was observed in the autumn group for both males and females. In conclusion, environmental arrangements are needed in order to reduce the mortality rate and improve performance in production periods that began in autumn and winter.
The Effect Of Staphylococcus Aureus Extracellular Products (Secp) On Performance,Selective Innate Immune Indexes, And Humoral Immune Response Against Avian Influenzaand Newcastle Disease Vaccines In Broiler Chickens, Teimour Tabari, Younes Papi, Esmaeil Azizi, Forough Talazadeh, Ramezan Ali Jafari, Masoud Ghorbanpoor
The Effect Of Staphylococcus Aureus Extracellular Products (Secp) On Performance,Selective Innate Immune Indexes, And Humoral Immune Response Against Avian Influenzaand Newcastle Disease Vaccines In Broiler Chickens, Teimour Tabari, Younes Papi, Esmaeil Azizi, Forough Talazadeh, Ramezan Ali Jafari, Masoud Ghorbanpoor
Turkish Journal of Veterinary & Animal Sciences
Improving the immune response is important for many reasons such as vaccine failure, immunosuppressive diseases, and antibiotics misuse. Research on materials likely to have immune-enhancing effects has been on the rise. Factors, substances, or compounds that can regulate different functions of the immune system can be used to enhance specific and even nonspecific responses to vaccines. Different amounts (0, 25, 50, and 100 μg) of Staphylococcus aureus extracellular products (SECP) were injected subcutaneously to different groups of chickens during the first vaccination against avian influenza (AI) and Newcastle disease (ND) viruses to investigate the effect of SECP on innate and …
Oxidative Stress In Calves With Enzootic Pneumonia, Mustafa Özbek, Cumali̇ Özkan
Oxidative Stress In Calves With Enzootic Pneumonia, Mustafa Özbek, Cumali̇ Özkan
Turkish Journal of Veterinary & Animal Sciences
This study was performed to evaluate the oxidative stress in calves with enzootic pneumonia. Ninety calves that were 2?6 months old were used in this study. Ten of these calves were healthy and used as the control group, while 80 were diagnosed with enzootic pneumonia according to the clinical examinations. The biochemical results showed that total oxidant status (TOS), nitric oxide (NO), malondialdehyde (MDA), and sialic acid (SA) levels were higher in calves with enzootic pneumonia than in the control group. While there was a statistically significant increase in TOS, MDA, and SA concentrations, there was not any statistically significant …
Comparative Evaluation Of The Effects Of Different Thawing Methods On Bull Spermcharacteristics With Computer-Assisted Semen Analysis, Murat Selçuk, Eser Akal, Burcu Esi̇n, Mustafa Yi̇ği̇t Ni̇zam, Merve Deni̇z Genç
Comparative Evaluation Of The Effects Of Different Thawing Methods On Bull Spermcharacteristics With Computer-Assisted Semen Analysis, Murat Selçuk, Eser Akal, Burcu Esi̇n, Mustafa Yi̇ği̇t Ni̇zam, Merve Deni̇z Genç
Turkish Journal of Veterinary & Animal Sciences
Postthaw survival of spermatozoa with high motility and vitality is required for successful artificial insemination. The aim of this study was to compare the effects of two different thawing methods on motility, morphology, kinematic parameters, and viability of spermatozoa with a computer-assisted semen analyzer (CASA). Frozen bull spermatozoa were thawed by using two different thawing procedures: 1) Water bath; straws were thawed in a water bath at 37 °C for 30 s. 2) Dry thawing system; straws were thawed in a dry thawing device at 37 °C for 30 s. A total of 10 straws were used for each thawing …
Retrospective Evaluation Of Factors Affecting Superovulatory Response In Embryoproduction In Simmental Cattle, Hüseyi̇n Erdem, Hasan Alkan, Tahi̇r Karaşahi̇n, Şükrü Dursun, Fatma Satilmiş, Mehmet Güler
Retrospective Evaluation Of Factors Affecting Superovulatory Response In Embryoproduction In Simmental Cattle, Hüseyi̇n Erdem, Hasan Alkan, Tahi̇r Karaşahi̇n, Şükrü Dursun, Fatma Satilmiş, Mehmet Güler
Turkish Journal of Veterinary & Animal Sciences
In the present study, it was aimed to investigate the effect of lactation status, days in milk (DIM), follicle stimulating hormone (FSH) dose, and repeated superstimulations on superovulation response and embryo yield in Simmental cattle. In the present study, 193 Simmental breed cattle (lactating, nonlactating, and heifer) were used as donors, of which 149 were superovulated only once and the other 44 were superovulated for 3 times. Progesterone-based estrus synchronization protocol was applied to the donors. Starting from day 7, FSH was given intramuscularly to donors in decreasing doses twice a day for 4 days. The donors were injected with …
Physiological And Pharmacological Roles Of Melatonin In The Pathophysiologicalcomponents Of Cellular Injury After Ischemic Stroke, Ertuğrul Kiliç, Berrak Çağlayan, Mustafa Caglar Beker
Physiological And Pharmacological Roles Of Melatonin In The Pathophysiologicalcomponents Of Cellular Injury After Ischemic Stroke, Ertuğrul Kiliç, Berrak Çağlayan, Mustafa Caglar Beker
Turkish Journal of Medical Sciences
Apart from its metabolic or physiological functions, melatonin has a potent cytoprotective activity in the physiological and pathological conditions. It is synthetized by the pineal gland and released into the blood circulation but particularly cerebrospinal fluid in a circadian manner. It can also easily diffuse through cellular membranes due its small size and lipophilic structure. Its cytoprotective activity has been linked to its potent free radical scavenger activity with the desirable characteristics of a clinically- reliable antioxidant. Melatonin detoxifies oxygen and nitrogen-based free radicals and oxidizing agents, including the highly toxic hydroxyl-and peroxynitrite radicals, initiating cellular damage. However, the cytoprotective …
Bmp And Tgfß Use And Release In Bone Regeneration, Zeynep Bal, Junichi Kushioka, Joe Kodama, Takashi Kaito, Hideki Yoshikawa, Petek Korkusuz, Feza Korkusuz
Bmp And Tgfß Use And Release In Bone Regeneration, Zeynep Bal, Junichi Kushioka, Joe Kodama, Takashi Kaito, Hideki Yoshikawa, Petek Korkusuz, Feza Korkusuz
Turkish Journal of Medical Sciences
A fracture that does not unite in nine months is defined as nonunion. Nonunion is common in fragmented fractures and large bone defects where vascularization is impaired. The distal third of the tibia, the scaphoid bone or the talus fractures are furthermore prone to nonunion. Open fractures and spinal fusion cases also need special monitoring for healing. Bone tissue regeneration can be attained by autografts, allografts, xenografts and synthetic materials, however their limited availability and the increased surgical time as well as the donor site morbidity of autograft use, and lower probability of success, increased costs and disease transmission and …
Tuberous Sclerosis: A Review Of The Past, Present, And Future, Sanem Pinar Uysal, Mustafa Şahi̇n
Tuberous Sclerosis: A Review Of The Past, Present, And Future, Sanem Pinar Uysal, Mustafa Şahi̇n
Turkish Journal of Medical Sciences
Tuberous sclerosis complex (TSC) is an autosomal dominant, multisystem disorder that is characterized by cellular and tissue dysplasia in several organs. With the advent of genetic and molecular techniques, mutations in the TSC1 or TSC2 genes were discovered to be responsible for mTOR overactivation, which is the underlying mechanism of pathogenesis. TSC is a highly heterogenous clinical entity with variable presentations and severity of disease. The brain, heart, skin, eyes, kidneys, and lungs are commonly involved in this syndrome, with neurologic symptoms comprising a significant source of morbidity and mortality. In 2012, the diagnostic criteria for TSC were revised by …
Igg4-Related Disease: A Contemporary Review, Hazan Karadeni̇z, Augusto Vaglio
Igg4-Related Disease: A Contemporary Review, Hazan Karadeni̇z, Augusto Vaglio
Turkish Journal of Medical Sciences
Background/aim: Immunoglobulin G4-related disease (IgG4-RD), is an immune-mediated fibroinflammatory condition, which may involve multiple organs and mostly presents with high serum IgG4 levels and specific histopathological characteristics. As IgG4-RD is a relatively new entity the etiology, prevalence and epidemiologic knowledge is quite limited. Although involvement of almost all anatomical regions has been reported, the most commonly affected regions are pancreas, lacrimal glands, salivary glands, retroperitoneum, orbita, lymph nodes, kidney and lungs. Diagnosis is made with combined evaluation of clinical, radiological and histopathological findings. Typical histopathological features include storiform fibrosis, dense lymphoplasmacytic infiltrates and obliterative phlebitis. Its course is typically marked …
Graft-Versus-Cancereffect And Innovative Approaches In Thetreatment Of Refractorysolid Tumors, Uğur Şahi̇n, Taner Demi̇rer
Graft-Versus-Cancereffect And Innovative Approaches In Thetreatment Of Refractorysolid Tumors, Uğur Şahi̇n, Taner Demi̇rer
Turkish Journal of Medical Sciences
Background/aim: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) has been used for the treatment of various refractory solid tumors during the last two decades. After the demonstration of graft-versus-leukemia (GvL) effect in a leukemic murine model following allo-HSCT from other strains of mice, graft-versus-tumor (GvT) effect in a solid tumor after allo-HSCT has also been reported in a murine model in 1984. Several trials have reported the presence of a GvT effect in patients with various refractory solid tumors, including renal, ovarian and colon cancers, as well as soft tissue sarcomas [1]. The growing data on haploidentical transplants also indicate GvT …
Ankaferd Hemostat: From Molecules To Medicine, Rafi̇ye Çi̇ftçi̇ler, İbrahi̇m Celaletti̇n Haznedaroğlu
Ankaferd Hemostat: From Molecules To Medicine, Rafi̇ye Çi̇ftçi̇ler, İbrahi̇m Celaletti̇n Haznedaroğlu
Turkish Journal of Medical Sciences
Ankaferd hemostat (ABS; Ankaferd Blood Stopper® , İstanbul, Turkey) is a hemostatic agent having an impact on red blood cell-fibrinogen interactions. The hemostatic effect of ABS depends upon the quick promotion of a protein network, particularly fibrinogen gamma, in relation to the erythrocyte aggregation. The entire physiological process involves ABS-induced formation of the protein network by vital erythrocyte aggregation. Vital erythrocyte aggregation occurs with the spectrine, ankyrin, and actin proteins on the membrane of the red blood cells. ABS notably affects cell metabolism and cell cycle mechanisms. Meanwhile, ABS has antiproliferative effects on cancer cells. The aim of this review …
Thiol-Disulfide Homeostasis: An Integrated Approach With Biochemical And Clinical Aspects, Özcan Erel, Serpi̇l Erdoğan
Thiol-Disulfide Homeostasis: An Integrated Approach With Biochemical And Clinical Aspects, Özcan Erel, Serpi̇l Erdoğan
Turkish Journal of Medical Sciences
Dynamic thiol-disulfide homeostasis (TDH) is a new area has begun to attract more scrutiny. Dynamic TDH is reversal of thiol oxidation in proteins and represents the status of thiols (-SH) and disulfides (-S-S-). Organic compounds containing the sulfhydryl group is called thiol, composed of sulfur and hydrogen atoms. Disulfides are the most important class of dynamic, redox responsive covalent bonds build in between two thiol groups. For many years, thiol levels were analyzed by several methods. During last years, measurements of disulfide levels have been analyzed by a novel automated method, developed by Erel and Neselioglu. In this method, addition …
Data-Driven Identification Of Chemopreventive Agents For Breast Cancer, Deni̇z Can Güven, Cemal Orhan, Kazi̇m Şahi̇n, Fatih Mehmet Uçkun
Data-Driven Identification Of Chemopreventive Agents For Breast Cancer, Deni̇z Can Güven, Cemal Orhan, Kazi̇m Şahi̇n, Fatih Mehmet Uçkun
Turkish Journal of Medical Sciences
Preclinical animal models of breast cancer provide the opportunity to identify chemopreventive drugs with single-agent activity as well as effective multi-modality regimens for primary as well as secondary prevention in high-risk persons. Our group has used the 7,12-dimethylbenz(a)anthracene (DMBA) mouse model of carcinogen-induced breast cancer to explore the clinical potential of two tyrosine kinase inhibitors and a nucleoside analog as chemopreventive agents. All three agents exhibited promising preclinical activity both as monotherapy and as components of combination therapy with the standard chemotherapy drug paclitaxel. The tumors developing despite chemoprevention were not only small and grew slowly, but they also displayed …