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Articles 61 - 90 of 1022
Full-Text Articles in Entire DC Network
Phenotypic And Molecular Characterization And Antimicrobial Susceptibility Pattern Of Pasteurella And Mannheimia Species Obtained From Cattle And Sheep With Pneumonia, Eli̇f Karadeni̇z Pütür, Fati̇h Büyük, Yaren Ersoy
Phenotypic And Molecular Characterization And Antimicrobial Susceptibility Pattern Of Pasteurella And Mannheimia Species Obtained From Cattle And Sheep With Pneumonia, Eli̇f Karadeni̇z Pütür, Fati̇h Büyük, Yaren Ersoy
Turkish Journal of Veterinary & Animal Sciences
Among the heterogeneous Pasteurellaceae family, Pasteurella multocida and Mannheimia haemolytica are the pathogenic species that cause enzootic pneumonia in cattle and sheep. This study aimed to characterise Pasteurella and Mannheimia species obtained from pneumonia cases in cattle and sheep. 100 cattle and 100 sheep lungs diagnosed with infectious pneumonia as a result of histopathological examination were analyzed for Pasteurellaceae members by phenotypic methods, VITEK 2 Compact system and PCR. Antibiotic susceptibilities and phylogenetic analysis of the isolates were done by VITEK 2 Compact System and 16S rRNA-PCR, respectively. Seven Pasteurella multocida and 9 Mannheimia haemolytica were identified. All strains were …
Numerical Solutions Of Sird Model Of Covid-19 By Utilizing Pell-Lucascollocation Method, Gamze Yildirim, Şuayi̇p Yüzbaşi
Numerical Solutions Of Sird Model Of Covid-19 By Utilizing Pell-Lucascollocation Method, Gamze Yildirim, Şuayi̇p Yüzbaşi
Turkish Journal of Mathematics
This article presents an SIRD model based on the evolution of Coronavirus Disease 2019 (COVID-19) caused by SARS-CoV-2 from the coronavirus family. Firstly, we constitute Pell-Lucas collocation method (PLCM) for this model. According to method, the matrix forms of the Pell-Lucas polynomials (PLPs) are constituted. By utilizing this matrix forms, solution forms and all terms in this model are expressed in matrix form. Thus, PLCM transforms our model into a system of the matrix equations. By solving this system, the approximate solutions are obtained. In addition, the error analysis is also presented. In the examples of this study, we analyzed …
Development Of Graphene Oxide-Based Biosensing Platforms For Label-Free Bioelectronic Detection Of Pathogenic Microorganisms, Sezi̇n Yüksel, Fethi̇ye Ferda Yilmaz, Hüseyi̇n Taşli, Pinar Kara
Development Of Graphene Oxide-Based Biosensing Platforms For Label-Free Bioelectronic Detection Of Pathogenic Microorganisms, Sezi̇n Yüksel, Fethi̇ye Ferda Yilmaz, Hüseyi̇n Taşli, Pinar Kara
Turkish Journal of Chemistry
A novel electrochemical nanogenosensor devoted to clinical analysis is reported for label-free detection of pathogenic microorganisms in the present work. The designed biosensor is composed of graphene oxide-modified disposable pencil graphite electrodes as a sensing platform. Escherichia coli is used as a model case. A 5ʹ-aminohexyl-linked 22-base sequence probe representing the E. coli amplicon is immobilized onto sensor surfaces via carbodiimide chemistry. Hybridization is performed with denatured PCR amplicons of the bacteria. Detection is realized by transduction with the electrochemical impedance spectrometry technique. The selectivity of the designed genosensor is measured using Mycobacterium tuberculosis and Klebsiella pneumoniae sequences. Outstanding sensitivity …
A Nationwide Study: Prevalence Of Rheumatoid Factor And Anti- Citrullinated Peptide Positivity And Their Contribution To Rheumatoid Arthritis Diagnosis, Hasan Satiş, Abdulsamet Erden, Emre Bi̇lgi̇n, Gi̇zem Ayan, Berkan Armağan, Duygu Tecer, Alper Sari, Umut Kalyoncu, Murat Çağlayan, Mustafa Mahi̇r Ülgü, Mustafa Okan Ayvali, Nai̇m Ata, Şuayi̇p Bi̇ri̇nci̇
A Nationwide Study: Prevalence Of Rheumatoid Factor And Anti- Citrullinated Peptide Positivity And Their Contribution To Rheumatoid Arthritis Diagnosis, Hasan Satiş, Abdulsamet Erden, Emre Bi̇lgi̇n, Gi̇zem Ayan, Berkan Armağan, Duygu Tecer, Alper Sari, Umut Kalyoncu, Murat Çağlayan, Mustafa Mahi̇r Ülgü, Mustafa Okan Ayvali, Nai̇m Ata, Şuayi̇p Bi̇ri̇nci̇
Turkish Journal of Medical Sciences
AbstractAim: Rheumatoid factor (RF) and Anti Citrullinated Peptide (anti-CCP) is specific for rheumatoid arthritis (RA) diagnosis. However they could be positive in other disease and even healthy populations. It was aimed to investigate the prevalence of positive RF and anti-CCP antibodies in persons admitted to hospital for any reason and on a national scale.Material and Method: The National Electronic Health Database, which contains the clinical records of over eighty million people, is used to design this multi-center, retrospective cohort study. The subjects included in the study were divided into age groups in 10-year periods. RA cases were identified by using …
Role Of Ct-Based Body Composition Parameters In The Course Of Covid-19, Elçi̇n Aydin, Begüm Ergi̇n, Ezgi̇ Güvel Verdi̇, Özge Coşkun, Şükrü Şahi̇n, Ali̇ Haydar Baykan, Hi̇lal Şahi̇n
Role Of Ct-Based Body Composition Parameters In The Course Of Covid-19, Elçi̇n Aydin, Begüm Ergi̇n, Ezgi̇ Güvel Verdi̇, Özge Coşkun, Şükrü Şahi̇n, Ali̇ Haydar Baykan, Hi̇lal Şahi̇n
Turkish Journal of Medical Sciences
Background/aim: A significant correlation is observed between the course of coronavirus disease 2019 (COVID-19) and body composition parameters including visceral fat quantification, muscle mass, and hepatic attenuation. The aim of the study was to investigate the correlation between the extent of lung involvement and various computed tomography (CT) parameters, as well as laboratory findings in COVID-19 patients.Materials and methods: A retrospective analysis was conducted on 72 adult patients with laboratory-confirmed severe acute respiratory syndrome coronavirus 2 infection who underwent two consecutive thorax CT scans at least 2 weeks apart. The patients were divided into two groups, as progressive and nonprogressive, …
Hyoscine-N-Butylbromide In Treating Abdominal Pain Caused By Gastroenteritis: A Double-Blind Randomized Placebo Controlled Study, Çağdaş Yildirim, Gül Pamukçu Günaydin
Hyoscine-N-Butylbromide In Treating Abdominal Pain Caused By Gastroenteritis: A Double-Blind Randomized Placebo Controlled Study, Çağdaş Yildirim, Gül Pamukçu Günaydin
Turkish Journal of Medical Sciences
Background/aimHyoscine-N-Butylbromide (HBB) is an anticholinergic agent widely used to treat pain caused by spasms in the gastrointestinal and urogenital systems. The aim of this study was to compare the efficacy of HBB with placebo in treating abdominal cramping pain caused by acute gastroenteritis in the Emergency Department (ED).Materials and methodsThis was a prospective, double-blind, placebo-controlled, randomized trial conducted in a single-center academic ED, from September to November 2021. Patients aged 18-65 years with acute gastroenteritis symptoms included in the study. The study compared the efficacy of intravenous HBB (20 mg) with placebo. The primary outcome was the absolute change in …
Anatolian Medicinal Plants As Potential Antiviral Agents: Bridging Traditional Knowledge And Modern Science In The Fight Against Covid-19 And Related Viral Infections, Engi̇n Ti̇lkat, Israt Jahan, Ayşe Hoşer, Alevcan Kaplan, Oğuzhan Özdemi̇r, Ahmet Onay
Anatolian Medicinal Plants As Potential Antiviral Agents: Bridging Traditional Knowledge And Modern Science In The Fight Against Covid-19 And Related Viral Infections, Engi̇n Ti̇lkat, Israt Jahan, Ayşe Hoşer, Alevcan Kaplan, Oğuzhan Özdemi̇r, Ahmet Onay
Turkish Journal of Biology
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the worldwide coronavirus illness 2019 (COVID-19), often known as the coronavirus pandemic. Since December 2020 however, COVID-19 vaccines have been extensively administered in numerous countries. In addition to new antiviral medications, the treatment regimen also encompasses symptom management. In spite of sustained research efforts, the outbreak remains uncontrolled, with affected patients still lacking proper treatment. Consequently, this review serves as a valuable asset for researchers and practitioners aiming to delve into the yet unexplored potential of Anatolian flora in the fight against COVID-19 and other viral infections. Numerous …
The Sharp Edge Of Immunosuppressive Treatments: Infections, Aybegüm Özşahi̇n, Tuba İlgar, Sudem Mahmutoğlu Çolak, Kübra Akyüz, Meli̇h Gaffar Gözükara, Uğur Kostakoğlu, İlknur Esen Yildiz, Ayşe Ertürk
The Sharp Edge Of Immunosuppressive Treatments: Infections, Aybegüm Özşahi̇n, Tuba İlgar, Sudem Mahmutoğlu Çolak, Kübra Akyüz, Meli̇h Gaffar Gözükara, Uğur Kostakoğlu, İlknur Esen Yildiz, Ayşe Ertürk
Turkish Journal of Medical Sciences
Background and aim: Different side effects, including infections, are encountered in patients receiving anticytokines used for the treatment of severe coronavirus disease 2019 (COVID-19). The aim of this study was to evaluate the infections and the effects of these infections that develop in this patient group. Materials and Methods: This study included 208 patients who were followed-up with the diagnosis of severe COVID-19 in two different hospitals. Patient data were obtained retrospectively from the hospital information system. Results: Of the 208 patients included, 54 were in the anakinra group, and 154 were in the tocilizumab group. Of these patients, 73 …
Do Patients Infected With Human Coronavirus Before The Covid-19 Pandemic Have Less Risk Of Being Infected With Covid-19?, Gamze Şanlidağ İşbi̇len, Ayça Aydin Uysal, Seli̇n Yi̇ği̇t, Özgür Appak, Hi̇lal Si̇pahi̇, Gülendam Bozdayi, Arzu Sayiner, Candan Çi̇çek, Özlem Güzel Tunçcan, Oğuz Reşat Si̇pahi̇
Do Patients Infected With Human Coronavirus Before The Covid-19 Pandemic Have Less Risk Of Being Infected With Covid-19?, Gamze Şanlidağ İşbi̇len, Ayça Aydin Uysal, Seli̇n Yi̇ği̇t, Özgür Appak, Hi̇lal Si̇pahi̇, Gülendam Bozdayi, Arzu Sayiner, Candan Çi̇çek, Özlem Güzel Tunçcan, Oğuz Reşat Si̇pahi̇
Turkish Journal of Medical Sciences
Background/aim: Although seasonal human coronaviruses (HCoVs) have long been recognized as respiratory tract viruses, the newly identified SARS-CoV-2 caused a pandemic associated with severe respiratory failure. We aimed to evaluate the incidence of COVID-19 infection in patients diagnosed in three tertiary teaching hospitals, both with and without prior confirmed HCoV infection, and to compare these cohorts in terms of COVID-19 contraction.Materials and methods: In our study, we examined HCoV PCR-positive cases obtained retrospectively between January 2014 and March 2020 from three University Hospital Microbiology Laboratories (Cohort 1), as well as PCR-negative patients detected in the same PCR cycle as the …
Relationship Between Functional Status And Fatigue After Covid-19 Infection: A Multicenter Study From Türkiye, İpek Candemi̇r, Pinar Ergün, Di̇cle Kaymaz, Mustafa Engi̇n Şahi̇n, İpek Özmen, Eli̇f Yildirim, Asli Görek Di̇lektaşli, Büşra Yi̇ği̇tli̇ler, Ayten Odabaş, Deni̇z Kizilirmak, Seçi̇l Sari, Celaletti̇n Korkmaz, Cantürk Taşçi, Yakup Arslan, Sema Savci, Buse Kahraman, Ayli̇n Tanriverdi̇, Can Sevi̇nç, Melda Sağlam, Deni̇z İnal İnce, Naci̇ye Vardar Yağli, Ebru Kütükçü, Di̇lber Durmaz, Nesli̇han Durutürk, Gaye Ulubay, Lütfi̇ye Kiliç, Benan Çağlayan, Ayli̇n Moray, Sabri̇ Serhan Olcay, Güven Özkaya
Relationship Between Functional Status And Fatigue After Covid-19 Infection: A Multicenter Study From Türkiye, İpek Candemi̇r, Pinar Ergün, Di̇cle Kaymaz, Mustafa Engi̇n Şahi̇n, İpek Özmen, Eli̇f Yildirim, Asli Görek Di̇lektaşli, Büşra Yi̇ği̇tli̇ler, Ayten Odabaş, Deni̇z Kizilirmak, Seçi̇l Sari, Celaletti̇n Korkmaz, Cantürk Taşçi, Yakup Arslan, Sema Savci, Buse Kahraman, Ayli̇n Tanriverdi̇, Can Sevi̇nç, Melda Sağlam, Deni̇z İnal İnce, Naci̇ye Vardar Yağli, Ebru Kütükçü, Di̇lber Durmaz, Nesli̇han Durutürk, Gaye Ulubay, Lütfi̇ye Kiliç, Benan Çağlayan, Ayli̇n Moray, Sabri̇ Serhan Olcay, Güven Özkaya
Turkish Journal of Medical Sciences
Background/aim: Symptoms of COVID-19 may persist for months. One of the persistent symptoms of COVID-19 is fatigue, which reduces functional status. The relationship between fatigue, functional status, and various other factors has received little attention, which this study aims to address.. Materials and methods: Patients with COVID-19 infection were included in this multicenter cross-sectional study. Age, sex, body mass index (BMI), marital status, smoking status, presence and duration of chronic disease, comorbidity index, regular exercise habits, time since COVID-19 diagnosis, hospitalization status, length of hospital stay, intubation status, home oxygen therapy after discharge, participation in a pulmonary rehabilitation program, presence …
The Frequency Of Potentially Inappropriate Medication Usage In Community-Dwelling Oldest-Old People, Fuat Ni̇hat Özaydin
The Frequency Of Potentially Inappropriate Medication Usage In Community-Dwelling Oldest-Old People, Fuat Ni̇hat Özaydin
Turkish Journal of Medical Sciences
Background/aim: It is critically important to protect the health of the oldest-old people, as their hospitalization and death rates are high. The objective of this study was to analyze the prevalence of potentially inappropriate medication use among the community-dwelling oldest-old people and its association with their demographic characteristics. Materials and methods: Data were collected from real-world settings using the observational method for this descriptive study. An older adult aged ≥ 85 years old was defined as the oldest-old. The participants were visited in their homes. The generic names of the medications used, and the age, sex, and province of residence …
Comparison Of Bulut Index-Beta Method And Global Health Security Index: Results From World Countries, Tevfi̇k Bulut, Mehmet Top, Murat Atan, Burkay Genç
Comparison Of Bulut Index-Beta Method And Global Health Security Index: Results From World Countries, Tevfi̇k Bulut, Mehmet Top, Murat Atan, Burkay Genç
Turkish Journal of Medical Sciences
Background/aimThe Global Health Security Index (GHSI), which is used to assess global health security preparedness level of countries, and Bulut Index-Beta (BI-β) method, developed as a multi-criteria decision-making method, were compared in terms of global health security in the context of world countries. Thus, it is aimed to demonstrate feasibility of BI-β method by testing it on GHSI datasets and then to contribute to methodological development of GHSI.Materials and methodsData set of the study consists of the publicly available GHSI data set, which allows for comparative evaluation of countries. BI-β method and GHSI were used to compare countries in terms …
Identification Of Blood Meals In Field Collected Culex Pipiens, Anopheles Sacharovi And Culex Tritaeniorhynchus (Diptera: Culicidae) Using The Elisa Method, Fatma Bursali, Gi̇zem Anti̇ka, Sare İlknur Yavaşoğlu, Fati̇h Mehmet Şi̇mşek
Identification Of Blood Meals In Field Collected Culex Pipiens, Anopheles Sacharovi And Culex Tritaeniorhynchus (Diptera: Culicidae) Using The Elisa Method, Fatma Bursali, Gi̇zem Anti̇ka, Sare İlknur Yavaşoğlu, Fati̇h Mehmet Şi̇mşek
Turkish Journal of Zoology
Information obtained about the blood feeding behavior of mosquito populations in nature is important for understanding their vectorial capacity and evaluating their potential role in the transmission of vector-borne diseases. This study investigated the feeding patterns of Culex pipiens, Anopheles sacharovi and Culex tritaeniorhynchus by using ELISA method. A total of 435 blood-fed females were collected from the Aegean and Mediterranean regions of Türkiye between May 2021-September 2023. The types and numbers of potential domestic animal hosts were recorded in each village. Of the 372 blood meals tested, 348 gave a single host positive result mainly on bovine and human, …
Comparison Of Radiologic Findings Between Sars-Cov-2 And Other Respiratory Tract Viruses In Critically Ill Children During The Covid-19 Pandemic, Oktay Perk, Tanil Kendi̇rli̇, Emel Uyar, Bi̇rsel Şen Akova, Hati̇ce Albayrak, Hasan Ağin, Ebru Ati̇ke Ongun, Eşe Eda Turanli, Sare Güntülü Şik, Şahi̇n Si̇ncar, Gürkan Bozan, Demet Demi̇rkol, Nazan Ülgen Tekerek, Mey Tali̇p, Arzu Oto, Feyza İnceköy Gi̇rgi̇n, Ferhat Sari, Nuretti̇n Onur Kutlu, Altan Güneş, Ömer Suat Fi̇töz
Comparison Of Radiologic Findings Between Sars-Cov-2 And Other Respiratory Tract Viruses In Critically Ill Children During The Covid-19 Pandemic, Oktay Perk, Tanil Kendi̇rli̇, Emel Uyar, Bi̇rsel Şen Akova, Hati̇ce Albayrak, Hasan Ağin, Ebru Ati̇ke Ongun, Eşe Eda Turanli, Sare Güntülü Şik, Şahi̇n Si̇ncar, Gürkan Bozan, Demet Demi̇rkol, Nazan Ülgen Tekerek, Mey Tali̇p, Arzu Oto, Feyza İnceköy Gi̇rgi̇n, Ferhat Sari, Nuretti̇n Onur Kutlu, Altan Güneş, Ömer Suat Fi̇töz
Turkish Journal of Medical Sciences
Background/aim: This study was planned because the radiological distinction of COVID-19 and respiratory viral panel (RVP)-positive cases is necessary to prioritize intensive care needs and ensure non-COVID-19 cases are not overlooked. With that purpose, the objective of this study was to compare radiologic findings between SARS-CoV-2 and other respiratory airway viruses in critically ill children with suspected COVID-19 disease.Materials and methods: This study was conducted as a multicenter, retrospective, observational, and cohort study in 24 pediatric intensive care units between March 1 and May 31, 2020. SARS-CoV-2- or RVP polymerase chain reaction (PCR)-positive patients’ chest X-ray and thoracic computed tomography …
Short- And Long-Term Neurological Outcomes Of Congenital Cytomegalovirus Infection, Fati̇h Mehmet Aki̇f Özdemi̇r, Yasemi̇n Taşci Yildiz, Rüveyda Gümüşer Ci̇nni̇, Ayşegül Zenci̇roğlu, Deni̇z Yüksel
Short- And Long-Term Neurological Outcomes Of Congenital Cytomegalovirus Infection, Fati̇h Mehmet Aki̇f Özdemi̇r, Yasemi̇n Taşci Yildiz, Rüveyda Gümüşer Ci̇nni̇, Ayşegül Zenci̇roğlu, Deni̇z Yüksel
Turkish Journal of Medical Sciences
Background/aim: Cytomegalovirus (CMV) is the most common congenital viral infection. Although most children with congenital CMV (approximately 85%–90%) are asymptomatic at birth, findings such as sensorineural hearing loss, microcephaly, and neurodevelopmental retardation can be observed during the follow-up. Among the brain magnetic resonance imaging (MRI) findings of CMV are white matter abnormalities, polymicrogyria, and periventricular calcification. Since a definitive diagnosis of congenital CMV cannot be made after the neonatal period, the identification of the associated phenotype is diagnostically important, but data are limited in patients who have been retrospectively diagnosed with congenital CMV infection. The aim of this study was …
Non-Small Cell Lung Cancer Treatment: Current Status Of Drug Repurposing And Nanoparticle-Based Drug Delivery Systems, Tugba Gul Inci, Serap Acar, Di̇lek Balik
Non-Small Cell Lung Cancer Treatment: Current Status Of Drug Repurposing And Nanoparticle-Based Drug Delivery Systems, Tugba Gul Inci, Serap Acar, Di̇lek Balik
Turkish Journal of Biology
Drug repurposing is the strategy of drug utilization for a treatment option other than the intended indications and has increased over the past decades, especially within cancer nanomedicine. Cancer nanomedicine has been facilitated through nanoparticle-based (NP-based) delivery systems which can combat NSCLC via recent advances in nanotechnology and apply its benefits to existing drugs. An effective therapeutic solution could be gained via repurposing and accelerated via NP-based drug delivery systems. This review aims to present an overview of NSCLC treatments with a special focus on drug repurposing with details of clinical study advances and NP-based drug delivery systems for NSCLC. …
The Outcome In Pediatric Acute Myeloblastic Leukemia; Results Of The First-Line Treatment And Contribution Of Hematopoietic Stem Cell Transplantation To Survival Of Relapsed Patients, Nazan Sarper, Intzi Tachzin, Sema Aylan Gelen, Emine Zengi̇n
The Outcome In Pediatric Acute Myeloblastic Leukemia; Results Of The First-Line Treatment And Contribution Of Hematopoietic Stem Cell Transplantation To Survival Of Relapsed Patients, Nazan Sarper, Intzi Tachzin, Sema Aylan Gelen, Emine Zengi̇n
Turkish Journal of Medical Sciences
Background/aim: To analyze the long-term outcome of pediatric patients with acute myeloblastic leukemia.Materials and methods: Data from 69 patients 0–18 years of age diagnosed between December 2001 and October 2019 were analyzed in April 2023. Patients received MRC-AML10 chemotherapy (2ADE+MACE+MidAC). No maintenance chemotherapy or preventive cranial radiotherapy was administered. Twelve patients with Down syndrome and 15 patients with promyelocytic leukemia were in the cohort. Patients with Down syndrome received reduced chemotherapy (cumulative anthracycline 420 mg/m2, cytarabine 3.4 g/m2, etoposide 1400 mg/m2). ATRA was added to chemotherapy in promyelocytic leukemia.Results: Four patients (5.8%) died in the induction (two typhlitis, one intracranial …
Inbreeding Tolerance In Two Isolated Populations Of Harting’S Vole Microtus Hartingi(Rodentia, Arvicolinae), Tanya Zorenko, Larisa Petra Kaija
Inbreeding Tolerance In Two Isolated Populations Of Harting’S Vole Microtus Hartingi(Rodentia, Arvicolinae), Tanya Zorenko, Larisa Petra Kaija
Turkish Journal of Zoology
The adaptive effects of inbreeding are understudied, but accumulating evidence suggests that it plays a major adaptive role in speciation, as populations with a history of inbreeding are more prone to it. Differences in inbreeding tolerance in two populations of Microtus hartingi voles were studied through a series of experiments on reproductive behaviour and partner choice. Modelling an artificial polygyny via the formation of trios composed of a brother, sister, and an unrelated female has shown an uneven attitude towards inbreeding, which was closely linked to the reproduction strategy: voles of the Rhodopean population (RP) would reproduce communally with only …
Longitudinal Attacks Against Iterative Data Collection With Local Differential Privacy, Mehmet Emre Gürsoy
Longitudinal Attacks Against Iterative Data Collection With Local Differential Privacy, Mehmet Emre Gürsoy
Turkish Journal of Electrical Engineering and Computer Sciences
Local differential privacy (LDP) has recently emerged as an accepted standard for privacy-preserving collection of users’ data from smartphones and IoT devices. In many practical scenarios, users’ data needs to be collected repeatedly across multiple iterations. In such cases, although each collection satisfies LDP individually by itself, a longitudinal collection of multiple responses from the same user degrades that user’s privacy. To demonstrate this claim, in this paper, we propose longitudinal attacks against iterative data collection with LDP. We formulate a general Bayesian adversary model, and then individually show the application of this adversary model on six popular LDP protocols: …
Comparison Of Milk Microbiota Between Healthy And Mastitic Cows, Sibel Kizil, Fatma Esin Aydin, Cansu Önlen Güneri̇, Ufuk Ülker, Gürol Emekdaş, İbrahim Basmaci, Serkan Erat, Rıza Durmaz, Efsun Melike Çeçen, Asya Kazan
Comparison Of Milk Microbiota Between Healthy And Mastitic Cows, Sibel Kizil, Fatma Esin Aydin, Cansu Önlen Güneri̇, Ufuk Ülker, Gürol Emekdaş, İbrahim Basmaci, Serkan Erat, Rıza Durmaz, Efsun Melike Çeçen, Asya Kazan
Turkish Journal of Veterinary & Animal Sciences
Mammary gland infections occur due to bacterial changes in the mammary tissue. Studies conducted in recent years have reported variations in the most common bacteria differ according to geographical locations. California mastitis test (CMT), somatic cell count (SCC), and aerobic colony count (ACC) analyses were performed on approximately 50 mL of hygienically collected raw milk samples. Raw milk was also subjected to conventional bacteriological isolation and identification. Bacterial diversity and rates in raw milk were compared through metagenome analysis. Two samples, one from healthy milk and another from subclinical milk with mastitis, were independently tested to determine whether there were …
Investigation Of Molecular Detection Rate And Associated Risk Factors Of Psittacine Beak And Feather Disease Virus In Psittaciformes In Iran, Mojtaba Khosravi, Shoreh Alian Samakkhah, Rahem Khoshbakht
Investigation Of Molecular Detection Rate And Associated Risk Factors Of Psittacine Beak And Feather Disease Virus In Psittaciformes In Iran, Mojtaba Khosravi, Shoreh Alian Samakkhah, Rahem Khoshbakht
Turkish Journal of Veterinary & Animal Sciences
Psittacine beak and feather disease virus (PBFDV) is a significant viral pathogen affecting the development of beak and feather cells, leading to feather abnormalities in avian species. This study aimed to investigate the molecular detection rate of PBFDV among Psittaciformes in Iran and to evaluate the influence of factors such as sex, species, season, and bird origin on PBFDV prevalence. Feather samples were collected from 1335 Psittaciformes, including Agapornis roseicollis, Pyrrhura molinae, Myiopsitta monachus, Aratinga solstitialis, Nymphicus hollandicus, Psittacula krameri, Psittacus erithacus, Poicephalus senegalus, Eos bornea, and Agapornis fischeri, and subjected to polymerase chain reaction (PCR) for PBFDV detection. The …
Determination Of Antibiotic Resistance In Salmonella Typhimurium And Salmonella Kentucky Serotypes Of Animal Origin Using Conventional And Molecular Methods, Zeynep Şik, Mehmet Akan
Determination Of Antibiotic Resistance In Salmonella Typhimurium And Salmonella Kentucky Serotypes Of Animal Origin Using Conventional And Molecular Methods, Zeynep Şik, Mehmet Akan
Turkish Journal of Veterinary & Animal Sciences
The high incidence of multidrug-resistant Salmonella Typhimurium and Salmonella Kentucky isolates is a concern for human and animal health. This study aimed to investigate the antibiotic resistance determinants of a total of 150 S. Typhimurium and S. Kentucky isolates obtained from cows, calves, lambs, and poultry. Salmonella isolates were tested against 13 different antimicrobials using the Kirby-Bauer disc diffusion method, and genotypic antimicrobial resistance determinants were investigated by polymerase chain reaction. Significant differences were detected among serovars for gentamicin, streptomycin, ampicillin, sulfonamide, nalidixic acid, ciprofloxacin, and tetracycline resistance, with the rates of resistance to these antibiotics being determined to be …
Bioassay-Guided Purification And Identification Of Antimicrobial Compound From Corn Silk Extract And Postharvest Application Against Fusarium Verticillioides On Cherry Tomato, Ummara Khan, Rita-Cindy Aye-Ayire Sedjoah, Yuting Shao, Dyaaaldin Abdalmegeed, Zichao Wu, Zhihong Xin
Bioassay-Guided Purification And Identification Of Antimicrobial Compound From Corn Silk Extract And Postharvest Application Against Fusarium Verticillioides On Cherry Tomato, Ummara Khan, Rita-Cindy Aye-Ayire Sedjoah, Yuting Shao, Dyaaaldin Abdalmegeed, Zichao Wu, Zhihong Xin
Turkish Journal of Agriculture and Forestry
Corn silk (Stigma maydis), the silky hairs on top of maize, is commonly discarded as waste. Despite its traditional medicinal use in countries like China, the United States, France, and Turkey, its phytochemical and pharmacological attributes have received limited study. In this study, the agar well diffusion method was used to evaluate the antimicrobial activity of free and bound crude extracts from cornsilk obtained using different solvents. Compared to the free crude extract, the bound crude extract exhibited greater efficacy against the tested microorganisms. Consequently, sequential fractionation was performed on the bound crude extract, and it was found that the …
High Amniotic Fluid Fractalkine And Mip-1Β Levels Are Associated With Intrauterine Growth Restriction: A Prospective Cohort Study, Şehmus Pala, Remzi Atilgan, Nevin İlhan
High Amniotic Fluid Fractalkine And Mip-1Β Levels Are Associated With Intrauterine Growth Restriction: A Prospective Cohort Study, Şehmus Pala, Remzi Atilgan, Nevin İlhan
Turkish Journal of Medical Sciences
Proinflammatory chemokines have been shown to play crucial roles in implantation, spiral artery invasion, and thefetomaternal immunological response. In this context, we investigated the levels of fractalkine (CX3CL1) and chemokine CC motifligand 4 (CCL4 or MIP-1β) in maternal serum and amniotic fluids in pregnant women with intrauterine growth restriction (IUGR).Materials and methods: This prospective cohort study was carried out at Fırat University Obstetrics Clinic between January 1, 2022 andJuly 1, 2022. Group (G) 1: The control group consisted of 40 pregnant women who underwent elective cesarean section (CS) at 38–40weeks of gestation. G2: A total of 40 pregnant women with …
In Silico Study Of Bioactive Compounds Derived From Indonesian Marine Invertebrates As Novel Antituberculosis Agent, Ayu Masyita, Eri̇s Septiana, Asep Bayu, Bustanussalam Bustanussalam, Jonathan A. Panggabean, Fi̇rdayani̇ Firdayani, Tuti̇k Murniasih
In Silico Study Of Bioactive Compounds Derived From Indonesian Marine Invertebrates As Novel Antituberculosis Agent, Ayu Masyita, Eri̇s Septiana, Asep Bayu, Bustanussalam Bustanussalam, Jonathan A. Panggabean, Fi̇rdayani̇ Firdayani, Tuti̇k Murniasih
Turkish Journal of Medical Sciences
Background/aim: Tuberculosis has still become the most deadly disease globally. The problem of finding an effective therapeutic is one of the obstacles in the treatment of patients. Marine invertebrates were a treasure since they produced many active compounds. Following up on this issue, screening active compounds is very important. This study will explain the result of anti-tuberculosis screening of compounds derived from marine invertebrates using in silico and confirmed to the in vitro-data.Materials and methods: Three-dimensional (3D) structures of pantothenate kinase (MtPanK type 1, PDB ID: 4BFT), Mycobacterium tuberculosis InhA (MtInhA, PDB ID: 2X23), protein kinase B (PDB ID: 5U94), …
Tracking The Footsteps Of Burkholderia Mallei: Determination Of The Molecular Differences And Potential Resistance Genes, Dilek Dülger, Seda Eki̇ci̇, Mehmet Demi̇rci̇, Akın Yi̇ği̇n, Orkun Babacan
Tracking The Footsteps Of Burkholderia Mallei: Determination Of The Molecular Differences And Potential Resistance Genes, Dilek Dülger, Seda Eki̇ci̇, Mehmet Demi̇rci̇, Akın Yi̇ği̇n, Orkun Babacan
Turkish Journal of Medical Sciences
Chemical biological radiological nuclear threats are at an important point in the agenda of world health today, as theycan cause mass deaths. B. mallei attracts attention as a potential biological warfare agent due to its features such as multidrug resistance,a rapid transmission mechanism via aerosol, the absence of a complete treatment protocol for the infection it causes, and the absence ofan approved vaccine for protection against the bacteria. B. mallei suspect samples must be studied by experienced personnel in biosafetylevel III laboratories. B mallei is a difficult and troublesome pathogen to diagnose and many unknowns about B. mallei today. Therefore,the …
Clinical Characteristics And Disease Course Before And After Sars-Cov-2 Infection In A Large Cohort Of Systemic Sclerosis Patients, Aslıhan Avanoğlu Güler, Büşra Özçi̇men, Mesude Seda Aydoğdu, Alper Sari, Aliyeva Numune, Nazife Tüzün Ersan, Seda Çolak, Hazan Karadeni̇z, İbrahim Vasi̇, Hamit Küçük, Yasemin Yalçinkaya, Abdulsamet Erden, Mehmet Kayaalp, Mehmet Akif Öztürk, Berna Göker, Ahmet Omma, Sedat Yilmaz, Süleyman Serdar Koca, Murat İnanç, Ali Akdoğan, Abdurrahman Tufan
Clinical Characteristics And Disease Course Before And After Sars-Cov-2 Infection In A Large Cohort Of Systemic Sclerosis Patients, Aslıhan Avanoğlu Güler, Büşra Özçi̇men, Mesude Seda Aydoğdu, Alper Sari, Aliyeva Numune, Nazife Tüzün Ersan, Seda Çolak, Hazan Karadeni̇z, İbrahim Vasi̇, Hamit Küçük, Yasemin Yalçinkaya, Abdulsamet Erden, Mehmet Kayaalp, Mehmet Akif Öztürk, Berna Göker, Ahmet Omma, Sedat Yilmaz, Süleyman Serdar Koca, Murat İnanç, Ali Akdoğan, Abdurrahman Tufan
Turkish Journal of Medical Sciences
The objective of this study is to evaluate the clinical presentations and adverse outcomes of Coronavirus Disease 2019 (COVID-19) in patients with systemic sclerosis (SSc) and assess the impact of SSc features on the clinical course of COVID-19.Materials and methods: In this multicenter, retrospective study, SSc patients with COVID-19 were included. Clinical features of SSc, along with detailed COVID-19 data, were extracted from medical records and patient interviews.Results: The study included 112 patients (mean age 51.4 ± 12.8 years; 90.2% female). SSc-associated interstitial lung disease (ILD) was evident in 57.1% of the patients. The findings revealed hospitalization in 25.5%, respiratory …
Synthesis Of Silane- And Quaternary Ammonium-Bearing Copolymers And Application As A Coating Resin On Cotton Fabric, Ayşe Marti̇n, Nazgül Güler, İlknur Yerli̇, Hande Hançer, Tüli̇n Özbek, Tarik Eren
Synthesis Of Silane- And Quaternary Ammonium-Bearing Copolymers And Application As A Coating Resin On Cotton Fabric, Ayşe Marti̇n, Nazgül Güler, İlknur Yerli̇, Hande Hançer, Tüli̇n Özbek, Tarik Eren
Turkish Journal of Chemistry
In this study, silane and quaternary ammonium functional methacrylate monomers were synthesized and used to construct a copolymer using an emulsion polymerization technique to control the reaction rate. The copolymer was then designed using different ratios of silane and quaternary ammonium groups to investigate the relationship between the structure and properties. The presence of the ethoxy silane group in the copolymer series provided covalent bonding through the silanol group onto cotton fabric. The presence of cationic groups also helped to cover the fabric surface. After coating the cotton textile fabric, the resistance of the dye on the fabric surface to …
Synthesis And Singlet Oxygen Generation Of Boron- 2-(4,5-Dibromo-1h-Imidazole-2-Yl)-3,5-Dipyrazolopyridine Complex For Antimicrobial Photodynamic Therapy, Zeynep Ekmekçi̇, Seda Karaoğlu
Synthesis And Singlet Oxygen Generation Of Boron- 2-(4,5-Dibromo-1h-Imidazole-2-Yl)-3,5-Dipyrazolopyridine Complex For Antimicrobial Photodynamic Therapy, Zeynep Ekmekçi̇, Seda Karaoğlu
Turkish Journal of Chemistry
In this study, the pyridine side of a boron 2-(2'-pyridyl) imidazole (BOPIM) core, which has very few derivatives synthesized in the literature and can show fluorescence properties in solid form, was derivatized with 1-methylpyrazole, predicted to have activity against fungi or bacteria according to the literature. Additionally, its imidazole side was brominated to increase the efficiency of singlet oxygen production by increasing the intersystem crossing. The photophysical properties of the new synthesized BOPIM derivative were investigated in general organic solvents with different polarities. While the wavelength of the maximum absorbance was determined as 406 nm in CH2Cl2 and THF, the …
Ph Responsive Curcumin Released From Urea-Amine Group Functionalized Mesoporous Organosilica Nanoparticles, Osman Tayyar Arli, Yaşar Gök, Hali̇l Zeki̇ Gök
Ph Responsive Curcumin Released From Urea-Amine Group Functionalized Mesoporous Organosilica Nanoparticles, Osman Tayyar Arli, Yaşar Gök, Hali̇l Zeki̇ Gök
Turkish Journal of Chemistry
Studies on natural products with anticancer properties have gained more importance in recent years in order to not damage healthy tissues during cancer treatments or to perform the treatment causing the least damage. Curcumin is a common natural product with anticancer properties, but its low solubility, instability, and bioavailability have limited its use in clinical applications in cancer research. As a proposed solution to this problem, a new mesoporous organosilica nanocarrier (MON-A) functionalized with a 1,2-diphenylethane-1,2-diamine structure capable of pH-controlled release was prepared in this study. MON-A was characterized by TGA, BET, XRD, FT-IR, and SEM-EDS analyses. Dispersion of MON-A …