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Description Of A New Species Of Eriococcidae (Hemiptera:Coccoidea) From Turkey, Lerzan Erkiliç, Mehmet Bora Kaydan, Ferenc Kozar
Description Of A New Species Of Eriococcidae (Hemiptera:Coccoidea) From Turkey, Lerzan Erkiliç, Mehmet Bora Kaydan, Ferenc Kozar
Turkish Journal of Zoology
A new species of Eriococcidae (Hemiptera: Coccoidea), Proteriococcus lauri Erkılıç sp. nov., collected on Laurus nobilis in Turkey is described and illustrated based on the adult female, and first-instar nymph.
The Second Step In Vitro Trial Of Ankaferd® Bloodstopper®: Comparison With Other Hemostatic Agents, Emre Huri̇, Kadi̇r Turgay Akgül, Mehmet Özgür Yücel, Hesna Müzeyyen Astarci, Hüseyi̇n Üstün, Rüştü Cankon Germi̇yanoğlu
The Second Step In Vitro Trial Of Ankaferd® Bloodstopper®: Comparison With Other Hemostatic Agents, Emre Huri̇, Kadi̇r Turgay Akgül, Mehmet Özgür Yücel, Hesna Müzeyyen Astarci, Hüseyi̇n Üstün, Rüştü Cankon Germi̇yanoğlu
Turkish Journal of Medical Sciences
To investigate the efficacy of Ankaferd Bloodstopper (ABS) and compare ABS with the other hemostatic agents still used in urologic surgery. Materials and methods: Forty Wistar rats were divided into 5 groups: Group T (traditional), partial nephrectomy (PN) with hilar control as per the conventional technique; Group G (Glubran 2), conventional PN followed by the application of Glubran 2; Group F (FloSeal), FloSeal application to the resected area of the kidney; Group C (Celox), Celox was applied; Group A (ABS), Ankaferd was used. Warm ischemia time (WIT) and hemostasis time (HT) were recorded and histopathologic features were compared among the …
Shorebirds In The Gediz Delta (İzmir, Turkey): Breeding And Wintering Abundances, Distributions, And Seasonal Occurrences, Ortaç Onmuş, Mehmet Siki
Shorebirds In The Gediz Delta (İzmir, Turkey): Breeding And Wintering Abundances, Distributions, And Seasonal Occurrences, Ortaç Onmuş, Mehmet Siki
Turkish Journal of Zoology
The present study describes breeding and wintering abundances, distributions, and seasonal occurrences of shorebirds (waders) in the Gediz Delta (İzmir-Turkey). Breeding abundance and distribution, and wintering abundance data were collected by carrying out breeding bird surveys in 2002 and 2006, and waterbird censuses between 1990 and 2007, respectively. Seasonal occurrences were determined using 432 different observations corresponding to 5043 different records between 1990 and 2007. Thirty-eight wader species were observed with a weekly average of 22.5 ± 4.0. Breeding evidence was obtained for 9 species in 2002 and 8 species in 2006. Average number of waders identified during yearly mid-winter …
Cerceis Insolita N. Sp., A New Species Of Sphaeromatid Isopod Crustacean From The Coastal Waters Of Pakistan, Farzana Yousuf
Cerceis Insolita N. Sp., A New Species Of Sphaeromatid Isopod Crustacean From The Coastal Waters Of Pakistan, Farzana Yousuf
Turkish Journal of Zoology
Cerceis insolita n. sp. (Isopoda, Sphaeromatidae), from the rocky intertidal region of Manora Island, Karachi coast, Pakistan, is described. The species can be identified on the basis of the following characters: antenna 1, pleon, pleotelson, coxal plates, pleopods 4 and 5, and notably by the unusual female pereopod 1 merus being short, transversely expanded, with the distolateral angle laterally produced into circular structure; carpus short, transversely expanded, propodus stout, curved laterally, with convex medial and concave lateral margins, dactylus subtriangular, well-developed unguis and accessory unguis. Right pereopod 7 long, slender, merus distomedial angle produced into medially directed lobe. Left pereopod …
Seasonal Changes In Zooplankton Community Structure In Lake Küçükçekmece, İstanbul, Turkey, Songül Özçalkap, Mustafa Temel
Seasonal Changes In Zooplankton Community Structure In Lake Küçükçekmece, İstanbul, Turkey, Songül Özçalkap, Mustafa Temel
Turkish Journal of Zoology
The zooplankton community of Lake Küçükçekmece includes individuals from freshwater groups Rotifera and Cladocera, and also marine species Acartia clausi of the subclass Copepoda; Tintinnopsis nana, Favella sp. Jorgensen, 1924, and Strobilidium spiralis from the group Ciliata; Micronereis sp. Linnaeus, 1758 and Spio sp. Fabricius, 1785 from the class Polychaeta; Pleurobrachia pileus from the phylum Ctenophora; and Gammarus sp. Fabricius, 1775 from the order Amphipoda. Rotifera was the dominant group for each season studied. In autumn, dominant specimens included Bosmina longirostris, Spio sp. Fabricius, 1785, Pleurobrachia pileus, the cypris and nauplius larva of Balanus sp., and veliger larva. In winter, …
Herb Gallwasp Neaylax Salviae (Giraud, 1859) (Hymenoptera, Aylacini) – New Record From Turkey, Yusuf Katilmiş, Suat Kiyak
Herb Gallwasp Neaylax Salviae (Giraud, 1859) (Hymenoptera, Aylacini) – New Record From Turkey, Yusuf Katilmiş, Suat Kiyak
Turkish Journal of Zoology
Here we report a new record for Neaylax salviae (Giraud, 1859) (Hymenoptera, Aylacini) on Salvia officinalis L. (Lamiaceae) in the inland Aegean region of Turkey. We give details on the geographical distribution and host. Neaylax salviae (Giraud, 1859) is a new record on the genus level for Turkish fauna.
Age, Growth And Reproduction Of Four-Spotted Goby, Deltentosteus Quadrimaculatus (Valenciennes, 1837), In İzmir Bay (Central Aegean Sea), Gülnur Meti̇n, Akin Türker İlkyaz, Ozan Soykan, Hasan Tuncay Kinacigi̇l
Age, Growth And Reproduction Of Four-Spotted Goby, Deltentosteus Quadrimaculatus (Valenciennes, 1837), In İzmir Bay (Central Aegean Sea), Gülnur Meti̇n, Akin Türker İlkyaz, Ozan Soykan, Hasan Tuncay Kinacigi̇l
Turkish Journal of Zoology
Length distribution, sex ratio, length-weight relationship, age, growth, spawning period, age, and length at first maturity of four-spotted goby inhabiting İzmir Bay were investigated. A total of 1696 four-spotted goby were collected by trawl hauls between July 2004 and June 2007. The size of the fish sampled ranged from 3.1 to 9.2 cm total length. The samples were composed of 31.1% females, 27.7% males, and 41.2% juvenile individuals, with a female to male ratio of 1:0.89. The age of the fish ranged from 1 to 5 years. The length-weight relationship and the von Bertalanffy growth function were estimated for all …
Length-Weight Relationships For 21 Fish Species Caught In The Argolikos Gulf (Central Aegean Sea, Eastern Mediterranean), Kostas Kapiris, Dimitris Klaoudatos
Length-Weight Relationships For 21 Fish Species Caught In The Argolikos Gulf (Central Aegean Sea, Eastern Mediterranean), Kostas Kapiris, Dimitris Klaoudatos
Turkish Journal of Zoology
The length-weight relationship for both sexes of 21 fish species caught in Argolikos Gulf (central Aegean Sea, eastern Mediterranean), using a variety of fishing gear, was estimated for the first time. Fishing took place between August 2007 and August 2008, and the fishing gear used included gill and trammel nets, long lines, and beach seines from 58 inshore fishing vessels. Individuals caught by trammel nets were usually longer and heavier than those collected by other fishing gear. The allometric coefficient (b) for the majority of species (59%) was statistically significantly higher than 3.0, indicating positive allometry between length and weight …
Alterations In Ion Levels Of Freshwater Fish Oreochromis Niloticus Following Acute And Chronic Exposures To Five Heavy Metals, Gülüzar Atli, Mustafa Canli
Alterations In Ion Levels Of Freshwater Fish Oreochromis Niloticus Following Acute And Chronic Exposures To Five Heavy Metals, Gülüzar Atli, Mustafa Canli
Turkish Journal of Zoology
Freshwater fish, Oreochromis niloticus, were individually exposed to 0, 0.1, 0.5, 1.0, and 1.5 µg/mL of Cu^{2+}, Cd^{2+}, Cr^{6+}, Ag^+, and Zn^{2+} for 96 h (acute) and 0.05 µg/mL concentrations of the same metals for 0, 5, 10, 20, and 30 days (chronic). Following each period, metal accumulation and ion levels (Na^+, K^+, Ca^{+2}, and Mg^{+2}) were measured in the gills, kidneys, and muscles. Except for Ag^+, none of the metals killed the fish within 30 days. Silver killed all the fish within 16 days. With the exceptions of Ag^+ and Cr^{6+}, as their levels were below detection limits, metal …
Population Dynamics Of Parthenium Hysterophorus (Asteraceae) And Its Biological Suppression Through Cassia Occidentalis (Caesalpiniaceae), Jai Knox, Disha Jaggi, Manoj Stephen Paul
Population Dynamics Of Parthenium Hysterophorus (Asteraceae) And Its Biological Suppression Through Cassia Occidentalis (Caesalpiniaceae), Jai Knox, Disha Jaggi, Manoj Stephen Paul
Turkish Journal of Botany
Phytosociological analysis performed over 2005 to 2009 revealed that Cassia occidentalis L. is a dominant species at 3 of 4 sites in Agra district, India, that were previously observed to be dominated by heavy populations of Parthenium hysterophorus L. In order to determine the role of biomolecular interaction, i.e. the allelopathic effect, if any, on this shift of floral pattern effects, aqueous shoot and root cold leachates were determined on seed germination, shoot cut bioassay, seedling bioassay, chlorophyll, nitrogen, and protein content of P. hysterophorus. A significant reduction in germination percentage, shoot cut bioassay, seedling bioassay, and chlorophyll of P. …
A Comparative Assessment Of Fruit Formation In Some Orchid Species From The Southern Caucasus Region, Houshang Nosrati, Roghieh Hajiboland, Ahmad Razban-Haghighi, Maryam Nikniazi
A Comparative Assessment Of Fruit Formation In Some Orchid Species From The Southern Caucasus Region, Houshang Nosrati, Roghieh Hajiboland, Ahmad Razban-Haghighi, Maryam Nikniazi
Turkish Journal of Botany
The distribution and population size of 5 orchid species (Cephalanthera longifolia, Orchis simia, Platanthera bifolia, Dactylorhiza romana, and Ophrys scolopax) were studied in the southern Caucasus based on the individual numbers in a given area. The fruit set was recorded for the latter 3 species and compared in natural and control groups (pollinators prevented) for D. romana and O. scolopax. We compared the obtained fruit set values with those reported from other regions. The distributions of the 5 species were completely fragmented and the population sizes were extremely small. This is the first report of O. scolopax from the region, …
Double-Layer Mesh Hernioplasty For Repairing Umbilical Hernias In 10 Goats*, Jose M. Vilar, Juan A. Corbera, Giuseppe Spinella
Double-Layer Mesh Hernioplasty For Repairing Umbilical Hernias In 10 Goats*, Jose M. Vilar, Juan A. Corbera, Giuseppe Spinella
Turkish Journal of Veterinary & Animal Sciences
Umbilical hernias in goats are uncommon and can vary in their etiology and management. Hernioplasty can be done by closing the abdominal wall with a horizontal mattress pattern using absorbable sutures. However, larger defects (hernial ring size >3 cm) generally require the use of prosthetic materials that allow for a tension-free repair. In this study, 10 young female goats with umbilical hernias and hernial ring sizes ranging from 7-10 cm in width were treated using a double-layer polypropylene mesh. An ultrasonographic examination was performed to assess healing and connective tissue production.
Cicer Uludereensis Dönmez: A New Species Of Cicer (Chickpea) (Fabaceae) From Around The Fertile Crescent, Se Turkey, Ali̇ Aslan Dönmez
Cicer Uludereensis Dönmez: A New Species Of Cicer (Chickpea) (Fabaceae) From Around The Fertile Crescent, Se Turkey, Ali̇ Aslan Dönmez
Turkish Journal of Botany
The genus Cicer L. includes an important crop plant, chickpea, which has been used as a protein source since prehistoric times. Specimens of a native Cicer have been collected and described from south-east Turkey. This new species, Cicer uludereensis Dönmez sp. nova, is distinct from a closely allied species, Cicer isauricum P.H.Davis, by its fine and more numerous teeth per leaflet, larger stipules, and narrower fruit with almost smooth seed surface. An illustration and a distribution map of the new species are provided and observations on the population are discussed.
Pollen Morphology Of The Genus Seseli L. (Umbelliferae) In Turkey, Ebru Doğan Güner, Hayri̇ Duman, Nur Münevver Pinar
Pollen Morphology Of The Genus Seseli L. (Umbelliferae) In Turkey, Ebru Doğan Güner, Hayri̇ Duman, Nur Münevver Pinar
Turkish Journal of Botany
Morphological features of pollen of 11 Turkish taxa belonging to the complex genus Seseli L. were examined using light and scanning electron microscopy. On the basis of exine sculpturing, 3 main types were recognised in Seseli: Type 1, rugulate at equator, psilate-perforate at pole; Type 2, striate-reticulate at equator, rugulate at pole; and Type 3, rugulate at equator, striate at pole. The study revealed that palynological characters display taxonomic significance in the genus.
Rare And Endemic Species: Why Are They Prone To Extinction?, Kani̇ Işik
Rare And Endemic Species: Why Are They Prone To Extinction?, Kani̇ Işik
Turkish Journal of Botany
A species is considered to be "rare" if it exhibits any one of the following attributes: (1) naturally occurs in a narrow geographical area, (2) occupies only one or a few specialised habitats, (3) forms only small population(s) in its range. An "endemic" species, however, grows naturally in a single geographical area, the size of which could be either narrow or relatively large. Not all endemic species are rare, just as not all rare species must necessarily be endemic. Many rare and/or endemic species exhibit one or more of the following attributes which make them especially prone to extinction: (1) …
Şerefeddin Sabuncuoğlu’S Drawings Of Gyneco-Obstetric Instruments, Nuri̇ Seli̇m Kadioğlu, Oya Ögenler, İlter Uzel
Şerefeddin Sabuncuoğlu’S Drawings Of Gyneco-Obstetric Instruments, Nuri̇ Seli̇m Kadioğlu, Oya Ögenler, İlter Uzel
Turkish Journal of Medical Sciences
The purpose of our study was to determine the contribution of Şerefeddin Sabuncuoğlu's achievement to bring gynecology to the modern knowledge level. The gynecological tools in the achievement of Serefeddin Sabuncuoğlu, who is the late period representative of classical medical paradigm, are examined in connection with the achievement of Zahravi, which belongs to the classical medical literature. It was determined that in the long time interval from Zahravi to Sabuncuoğlu a limited advancement occurred in medical knowledge, and that the differences between the achievements of the 2 doctors are important for reflecting the development between the 2 periods.
Effects Of 50 Hz Electric Field On Malondyaldehide And Nitric Oxide Levels In Spinal Cord Of Rats At Prenatal Plus Postnatal Period, Ertuğrul Uzar, Haci Ramazan Yilmaz, Mustafa Yilmaz, Efkan Uz, Vedat Ali̇ Yürekli̇, Bumi̇n Dündar, Hasan Rifat Koyuncuoglu, Selçuk Çömlekçi̇
Effects Of 50 Hz Electric Field On Malondyaldehide And Nitric Oxide Levels In Spinal Cord Of Rats At Prenatal Plus Postnatal Period, Ertuğrul Uzar, Haci Ramazan Yilmaz, Mustafa Yilmaz, Efkan Uz, Vedat Ali̇ Yürekli̇, Bumi̇n Dündar, Hasan Rifat Koyuncuoglu, Selçuk Çömlekçi̇
Turkish Journal of Medical Sciences
The effect of 50 Hz electric field (EF) on developing neural tissues is not known. We aimed to determine whether there would be any oxidative stress effect of 50 Hz EF on developing spinal cord tissues of pup rats by evaluating malondialdehyde (MDA), nitric oxide (NO) levels, and antioxidant enzyme activities such as superoxide dismutase (SOD) and catalase (CAT) measurement. Materials and methods: In the prenatal+postnatal group, the pregnant rat was exposed to continuous EF at 50 Hz 10 kV/s until delivery. Then the female pups of this group (n = 7) were exposed to EF at the same doses …
Urginea Maritima (L.) Baker (Liliaceae) Extract Induces More Cytotoxicity Than Standard Chemotherapeutics In The A549 Non-Small Cell Lung Cancer (Nsclc) Cell Line, Hakan Bozcuk, Mustafa Özdoğan, Oktay Aykurt, Fati̇h Topçuoğlu, Hasan Öztürk, Deni̇z Eki̇nci̇, Asuman Karadeni̇z, Ayli̇n Mutlu, Durmuş Burgucu
Urginea Maritima (L.) Baker (Liliaceae) Extract Induces More Cytotoxicity Than Standard Chemotherapeutics In The A549 Non-Small Cell Lung Cancer (Nsclc) Cell Line, Hakan Bozcuk, Mustafa Özdoğan, Oktay Aykurt, Fati̇h Topçuoğlu, Hasan Öztürk, Deni̇z Eki̇nci̇, Asuman Karadeni̇z, Ayli̇n Mutlu, Durmuş Burgucu
Turkish Journal of Medical Sciences
Urginea maritima (Um) is a plant native to especially Turkey and the Mediterranean area. In this study, we investigated whether Um extract exerted cytotoxicity on cancer cells. Materials and methods: We made various extracts of Um. These extracts in varying concentrations were added to an A549 NSCLC cell culture, alone or with gemcitabine and/or cisplatin. Growth inhibition was tested by the MTT assay and an Annexin V-FITC apoptosis detection kit Results: The onion Um extract (1 µg/mL) was more cytotoxic than cisplatin (1 µg/mL), gemcitabine (1 nm/mL), and leaf Um extract (1 µg/mL) with P < 0.001, P = 0.097, and P < 0.001, respectively. The efficacy of Um extract was further improved by the addition of an antioxidant cocktail to an IC_{50} value of 0.02 µg/mL. Conclusion: Um extract has been shown for the first time to be a strong candidate for drug development in solid tumors. Our studies continue to further define the specific antitumor compound(s) in this extract.
Relationship Between Pon1 Phenotype And Headache Duration In Migraine Patients, Şahbetti̇n Selek, Recep Alp, Selen İlhan Alp, Abdullah Taşkin
Relationship Between Pon1 Phenotype And Headache Duration In Migraine Patients, Şahbetti̇n Selek, Recep Alp, Selen İlhan Alp, Abdullah Taşkin
Turkish Journal of Medical Sciences
The available data on the activity of paraoxonase-1 (PON1) in patients suffering from migraine without aura (MWoA) is scarce. The present study was conducted to fulfill the objective of investigating the probability of an association between PON1 phenotype distribution and headache duration in patients suffering from MWoA. Materials and methods: Seventy-six patients who suffer from MWoA and were not experiencing attacks at the time and 65 healthy volunteers were enrolled for the purpose of evaluation in the present study. Results: The levels of serum paraoxonase, arylesterase activities, and lipid hydroperoxide (LOOH) were determined for these subjects. The results obtained revealed …
Serum Paraoxonase And Arylesterase Activities In Iron Deficiency Anemia During Pregnancy, Hakan Camuzcuoğlu, Harun Toy, Mehmet Vural, Aysun Camuzcuoğlu, Abdullah Taşkin, Haki̇m Çeli̇k
Serum Paraoxonase And Arylesterase Activities In Iron Deficiency Anemia During Pregnancy, Hakan Camuzcuoğlu, Harun Toy, Mehmet Vural, Aysun Camuzcuoğlu, Abdullah Taşkin, Haki̇m Çeli̇k
Turkish Journal of Medical Sciences
To investigate serum paraoxonase and arylesterase activities, and lipid hydroperoxide levels in pregnant women with iron deficiency anemia. Materials and methods: Paraoxonase and arylesterase activities, and lipid hydroperoxide levels were assessed for pregnant women with iron deficiency anemia (n = 50) and controls (n = 70). Serum basal and salt-stimulated paraoxonase, and arylesterase activities were measured spectrophotometrically. The lipid hydroperoxide levels were measured by ferrous ion oxidation xylenol orange assay. In addition, lipid parameters were determined by routine laboratory methods. Results: Basal and salt-stimulated paraoxonase, and arylesterase activities were significantly lower (P = 0.026, P = 0.031, and P = …
Immunomodulatory Role Of Leptin Treatment In Experimental Sepsis Caused By Gram Negative Bacteria, Cemi̇le Koca, Havva Şahi̇n Kavakli, Özlem Alici
Immunomodulatory Role Of Leptin Treatment In Experimental Sepsis Caused By Gram Negative Bacteria, Cemi̇le Koca, Havva Şahi̇n Kavakli, Özlem Alici
Turkish Journal of Medical Sciences
To investigate the effect of leptin treatment on circulating inflammatory cytokines and on tissue damage in experimental rat model of gram-negative sepsis. Materials and methods: Adult male Wistar rats, 28 in total, were randomly divided into 4 groups (n = 7): sham, leptin, sepsis, and sepsis group treated with leptin (sepsis+leptin). Sepsis was induced by intraperitoneal (ip) injection of 2 × 10^{10} CFU of Escherichia coli ATCC 25922. Leptin and sepsis+leptin groups received a single dose ip 0.1 mg/kg leptin, while sham group received 1 mL of ip saline. Rats were sacrificed 24 h after the induction of sepsis. Blood …
Glutamate Dehydrogenase And Triose-Phosphate-Isomerase Coding Genes For Detection And Genetic Characterization Of Giardia Lamblia In Human Feces By Pcr And Pcr-Rflp*, Kareem Hatam Nahavandi, Esmaeel Fallah, Mohammad Asgharzadeh, Nasrin Mirsamadi, Behroz Mahdavipour
Glutamate Dehydrogenase And Triose-Phosphate-Isomerase Coding Genes For Detection And Genetic Characterization Of Giardia Lamblia In Human Feces By Pcr And Pcr-Rflp*, Kareem Hatam Nahavandi, Esmaeel Fallah, Mohammad Asgharzadeh, Nasrin Mirsamadi, Behroz Mahdavipour
Turkish Journal of Medical Sciences
The purpose of this study was comparison of the glutamate dehydrogenase (gdh) and triose phosphate isomerase (tpi) genes for detection and genetic characterization of Giardia lamblia (G. lamblia) in human stool by polymerase chain reaction (PCR) and PCR-restriction fragment length polymorphism (RFLP). Our assay was specific and distinguished between G. lamblia assemblages A and B. Materials and methods: Among the 325 stool samples obtained from patients with acute gastroenteritis hospitalized in the Pediatric Hospital and infected humans referred to the Tabriz Reference Laboratory (TRL), 34 Giardia-positive stool samples were identified by conventional techniques. Two assays-PCR and PCR-RFLP-targeting the tpi and …
Investigation Of Toxin Genes In Staphylococcus Aureus Strains Isolated In Mustafa Kemal University Hospital, Cemi̇l Demi̇r, Özkan Aslantaş, Ni̇zami̇ Duran, Sabahatti̇n Ocak, Burçi̇n Özer
Investigation Of Toxin Genes In Staphylococcus Aureus Strains Isolated In Mustafa Kemal University Hospital, Cemi̇l Demi̇r, Özkan Aslantaş, Ni̇zami̇ Duran, Sabahatti̇n Ocak, Burçi̇n Özer
Turkish Journal of Medical Sciences
The aim of this study was to investigate the presence of genes encoding staphylococcal enterotoxins (SEs), exfoliative toxins (ETAs, ETBs), and toxic shock syndrome toxin-1 (TSST-1) by polymerase chain reaction (PCR) in Staphylococcus aureus strains isolated from various clinical samples from the Mustafa Kemal University Hospital. In addition, PCR-based restriction fragment length polymorphism (RFLP) analysis of the coa gene was employed to genotype the isolates. Materials and methods: A total of 120 S. aureus strains isolated from various clinical samples (blood, wounds, urine, conjuctival swabs, and tracheal aspirate) over a 1 year period, 2007-2008, were used in this study. Results: …
The Protective Effect Of Dexamethasone And Lactate Against Cisplatin-Induced Ototoxicity, Ari̇f Şanli, Sedat Aydin, Zeynep Alev Sarisoy, Mustafa Paksoy, Emi̇n Ayduran, Özlem Çelebi̇ Erdi̇vanli
The Protective Effect Of Dexamethasone And Lactate Against Cisplatin-Induced Ototoxicity, Ari̇f Şanli, Sedat Aydin, Zeynep Alev Sarisoy, Mustafa Paksoy, Emi̇n Ayduran, Özlem Çelebi̇ Erdi̇vanli
Turkish Journal of Medical Sciences
To compare the protective effect of dexamethasone and lactate against cisplatin-induced ototoxicity. Materials and methods: Thirty Wistar rats were randomly divided into 4 groups. After the rats were sedated with intraperitoneal (IP) ketamine hydrochloride (50 mg/kg) and xylazine (7.5 mg/kg), baseline ABRs (auditory brainstem evoked responses) were measured in response to clicks and tone pips of 4, 8, 12, and 16 kHz. After auditory thresholds were determined, the animals received drug administration as follows: Group 1 (n: 6) received intratympanic (IT) saline (0.9% NaCl) solution, Group 2 (n: 8) IP cisplatin (20 mg/kg) alone, Group 3 (n: 8) IT dexamethasone …
The Effect Of Alkali Burn On Corneal Glutathione Peroxidase Activities In Rabbits, İlknur Akyol Salman, Ahmet Kiziltunç, Orhan Baykal
The Effect Of Alkali Burn On Corneal Glutathione Peroxidase Activities In Rabbits, İlknur Akyol Salman, Ahmet Kiziltunç, Orhan Baykal
Turkish Journal of Medical Sciences
Glutathione peroxidase (GPx) is an important corneal defense enzyme for protecting against hydrogen peroxides and lipid peroxides. In the present study, corneal GPx activities after alkali burn of the cornea were evaluated in rabbits. Materials and methods: Corneal alkali burn was created in the right eye of 10 rabbits by applying a 6 mm round filter paper soaked in 1 N NaOH onto the central cornea for 60 s. The right eyes of 10 healthy rabbits served as controls. The corneal GPx activities were determined by the method of Paglia and Valentina, 10 days after the burn. Results: GPx activities …
The Effect Of Caffeine On Oxidative Stress In Liver And Heart Tissues Of Rats, Hati̇ce Paşaoğlu, Fatma Ebru Ofluoğlu Demi̇r, Canan Yilmaz-Demi̇rtaş, Ahmed Hussein, Özge Tuğçe Paşaoğlu
The Effect Of Caffeine On Oxidative Stress In Liver And Heart Tissues Of Rats, Hati̇ce Paşaoğlu, Fatma Ebru Ofluoğlu Demi̇r, Canan Yilmaz-Demi̇rtaş, Ahmed Hussein, Özge Tuğçe Paşaoğlu
Turkish Journal of Medical Sciences
To investigate the effect of caffeine on the levels of malondialdehyde (MDA), nitric oxide (NO), and advanced oxidation protein products (AOPP) in the liver and heart tissues of rats. Materials and methods: The current study included 30 rats, which were divided into 3 groups: a control group and 2 caffeine-treated groups. Group 1 was given caffeine at 30 mg/kg and Group 2 was given caffeine at 100 mg/kg (a high nontoxic dose) for 14 days. Results: MDA and AOPP levels in the liver tissue of the caffeine-treated groups decreased significantly as a result of the dose. MDA and AOPP levels …
The Effects Of P53 Inhibition Using Pifithrin-Α On Acute Necrotizing Pancreatitis In Rats, Etem Alhan, Aki̇f Ci̇nel, Mehmet Cengi̇z Erçi̇n, Serdar Türkyilmaz, Bi̇rgül Vani̇zor Kural, Murat Alper, Deni̇z Fi̇li̇nte
The Effects Of P53 Inhibition Using Pifithrin-Α On Acute Necrotizing Pancreatitis In Rats, Etem Alhan, Aki̇f Ci̇nel, Mehmet Cengi̇z Erçi̇n, Serdar Türkyilmaz, Bi̇rgül Vani̇zor Kural, Murat Alper, Deni̇z Fi̇li̇nte
Turkish Journal of Medical Sciences
To investigate the effects of p53 inhibition using pifithrin-\alpha (PFA) on acute necrotizing pancreatitis (ANP) induced by glycodeoxycholic acid in rats. The role of p53 during acute pancreatitis is unclear. Materials and methods: Rats were divided into 4 groups, 2 of which were initially given only saline (the sham group) and 2 of which were given glycodeoxycholic acid in order to induce ANP. Each group was then identified according to treatment plan: sham+saline, sham+PFA, ANP+saline, or ANP+PFA. The study then investigated the extent of acinar cell injury, apoptosis, mortality, systemic cardiorespiratory variables, functional capillary density (FCD), renal/hepatic functions, and changes …
Anti-Diabetic Effects Of An Alcoholic Extract Of Juglans Regia In An Animal Model, Jamshid Mohammadi, Khalil Saadipour, Hamdollah Delaviz, Bahram Mohammadi
Anti-Diabetic Effects Of An Alcoholic Extract Of Juglans Regia In An Animal Model, Jamshid Mohammadi, Khalil Saadipour, Hamdollah Delaviz, Bahram Mohammadi
Turkish Journal of Medical Sciences
Many traditional treatments have been recommended in the alternative system of medicine for treatment of diabetes mellitus. Juglans regia is one of the medicinal plants used in traditional Iranian medicine as a treatment for diabetes, but little scientific documentation supports its antidiabetic action. The purpose of this study was to investigate antidiabetic effect of J. regia leaves in type 1 diabetes induced animal model. Materials and methods: Four groups of animals were selected. Group I animals were fed a normal diet. Animals of groups II, III, and IV received streptozotocin. Animals of groups III and IV were treated with J. …