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Effect Of Dietary Aspergillus Meal Prebiotic On Growth Performance, Carcass Characteristics, Nutrient Digestibility, And Serum Lipid Profile In Broiler Chick Low-Protein Diets, Saeid Amirdahri, Hossein Janmohammadi, Akbar Taghizadeh, Abbas Rafat
Effect Of Dietary Aspergillus Meal Prebiotic On Growth Performance, Carcass Characteristics, Nutrient Digestibility, And Serum Lipid Profile In Broiler Chick Low-Protein Diets, Saeid Amirdahri, Hossein Janmohammadi, Akbar Taghizadeh, Abbas Rafat
Turkish Journal of Veterinary & Animal Sciences
The effects of 3 levels of commercial Aspergillus meal prebiotic (Fermacto®) in broiler diets with 2 levels of dietary crude protein (CP) on the growth performance, carcass characteristics, apparent ileal digestibility of CP and organic matter (OM), and serum lipid profile were evaluated using 240-day-old broiler chickens as a factorial arrangement in a completely randomized design. From the grower period, 3 groups received normal diets formulated to meet Ross-308 CP and other nutrient requirements with 3 levels of Fermacto®. The other 3 groups received experimental diets with 2% less CP, with the same levels of Fermacto®. None of the growth …
Reproductive Performance And Serum Concentrations Of Progesterone Of Heat-Stressed Holstein Heifers Subjected To Timed Artificial Insemination And Progesterone Supplementation, Abelardo Correa Calderon, Juan Augusto Hernandez Rivera, Leonel Avendaño Reyes, Ulises Macias Cruz, Raul Diaz Molina, Francisco Daniel Alvarez Valenzuela, Arnoldo Gonzalez Reyna
Reproductive Performance And Serum Concentrations Of Progesterone Of Heat-Stressed Holstein Heifers Subjected To Timed Artificial Insemination And Progesterone Supplementation, Abelardo Correa Calderon, Juan Augusto Hernandez Rivera, Leonel Avendaño Reyes, Ulises Macias Cruz, Raul Diaz Molina, Francisco Daniel Alvarez Valenzuela, Arnoldo Gonzalez Reyna
Turkish Journal of Veterinary & Animal Sciences
Sixty-nine Holstein heifers were used to evaluate the effect of progesterone supplementation after timed artificial insemination (TAI) on conception rates of heifers under heat stress. Heifers were randomly assigned to 1 of 3 treatments: 1) control treatment (C), visual detection of estrus. Heifers detected in estrous were inseminated according to the AM-PM procedure (n = 23); 2) TAI (n = 24), using a CIDR device (insert containing progesterone) placed intravaginally on day -10 and removed on day -2 with PGF2α given on day -3. Heifers were given 0.5 mg of ECP at CIDR insertion and a second injection (0.5 mg …
A Note On Phthirapteran Ectoparasites Infesting Yellow-Legged Green Pigeon Treron Phoenicoptera (Columbiformes: Columbidae), Aftab Ahmad, Gaurav Arya, Nayanci Bansal, Oldrich Sychra, Arun Kumar Saxena
A Note On Phthirapteran Ectoparasites Infesting Yellow-Legged Green Pigeon Treron Phoenicoptera (Columbiformes: Columbidae), Aftab Ahmad, Gaurav Arya, Nayanci Bansal, Oldrich Sychra, Arun Kumar Saxena
Turkish Journal of Veterinary & Animal Sciences
The present report records the simultaneous occurrence of ischnoceran lice Columbicola phoenicopterae and Coloceras setosum on the Yellow-legged Green Pigeon in India. The prevalence, intensity of infestation, range of infestation, and nature of the antennal sensilla of these 2 species on 12 of these pigeons have also been recorded.
The Effect Of Intrauterine Cephapirin Treatment After Insemination On Conception Rate In Repeat Breeder Dairy Cows Subjected To The Progesterone-Based Ovsynch Protocol, Ahmet Gümen, Gülnaz Meci̇toğlu, Abdulkadi̇r Keski̇n, Ebru Karakaya, Ali̇ Alkan, Umut Taşdemi̇r, Hayretti̇n Okut
The Effect Of Intrauterine Cephapirin Treatment After Insemination On Conception Rate In Repeat Breeder Dairy Cows Subjected To The Progesterone-Based Ovsynch Protocol, Ahmet Gümen, Gülnaz Meci̇toğlu, Abdulkadi̇r Keski̇n, Ebru Karakaya, Ali̇ Alkan, Umut Taşdemi̇r, Hayretti̇n Okut
Turkish Journal of Veterinary & Animal Sciences
Subclinical endometritis contributes to repeat breeder syndrome in dairy cows. This study evaluated the effect of intrauterine cephapirin benzathine administration after timed artificial insemination (TAI) on the conception rate (CR) in repeat breeder dairy cows. To determine the antibiotic effects, all cows (n = 335) that had more than 3 services with no clinical abnormalities of the reproductive tract received the same combined synchronisation protocol: an ear implant containing progestagen using the Ovsynch protocol and a third gonadotropin-releasing hormone (GnRH) administration 7 days after TAI. Cows in the treatment group (TRT; n = 160) received intrauterine cephapirin 12 h after …
Ultrasound Imaging, Biochemical Blood Analyses, And Weight Investigations Of Dissectible Fat Depots In New Zealand White Rabbits, Penka Yonkova, Anton Rusenov, Dean Kanakov, Dimitrinka Zapryanova, Ekaterina Vachkova, Ayşe Serbest, Rosen Dimitrov, Dimitar Kostov
Ultrasound Imaging, Biochemical Blood Analyses, And Weight Investigations Of Dissectible Fat Depots In New Zealand White Rabbits, Penka Yonkova, Anton Rusenov, Dean Kanakov, Dimitrinka Zapryanova, Ekaterina Vachkova, Ayşe Serbest, Rosen Dimitrov, Dimitar Kostov
Turkish Journal of Veterinary & Animal Sciences
The purpose of the present study was to evaluate changes in real-time ultrasound imaging traits and weight of dissectible fat depots (inguinal, interscapular, and perirenal) in rabbits with different body weights and to monitor the changes in blood glucose and constituents of lipid profiles. In this study, 18 clinically healthy male New Zealand white rabbits were used. The rabbits were fed with standard diet and were divided into 3 groups according to their body weight: group 1 at 1.06 ± 0.03 kg, group 2 at 2.1 ± 0.05 kg, and group 3 at 3.06 ± 0.03 kg. Examined by ultrasonography, …
Protective Effects Of Salvia Officinalis Extract Against Cyclophosphamide-Induced Genotoxicity And Oxidative Stress In Rats, Fulya Üstün Alkan, Feraye Esen Gürsel, Ati̇la Ateş, Mustafa Özyürek, Kubi̇lay Güçlü, Mehmet Altun
Protective Effects Of Salvia Officinalis Extract Against Cyclophosphamide-Induced Genotoxicity And Oxidative Stress In Rats, Fulya Üstün Alkan, Feraye Esen Gürsel, Ati̇la Ateş, Mustafa Özyürek, Kubi̇lay Güçlü, Mehmet Altun
Turkish Journal of Veterinary & Animal Sciences
Medicinal plants, especially rich in polyphenolic compounds, have been suggested to be chemopreventive on account of antioxidative properties. Salvia officinalis L., an aromatic and medicinal plant, is widely used in folk medicine and is well known for its antioxidant properties. Therefore, the present study was designed to investigate the antioxidative, possible genotoxic, and antigenotoxic potency of S. officinalis extract against cyclophosphamide (CYP)-induced oxidative stress and genotoxicity in Wistar albino rats. Animals were orally dosed with S. officinalis extract (50, 100, and 150 mg/kg body weight) for 7 days before the administration of a single intraperitoneal dose of CYP (40 mg/kg …
Ultrasonographic Evaluation Of Cricoarytenoideus Lateralis Muscle In Standardbred Horse, Fulvio Laus, Emanuele Paggi, Matteo Cerquetella, Beniamino Tesei
Ultrasonographic Evaluation Of Cricoarytenoideus Lateralis Muscle In Standardbred Horse, Fulvio Laus, Emanuele Paggi, Matteo Cerquetella, Beniamino Tesei
Turkish Journal of Veterinary & Animal Sciences
The cricoarytenoideus lateralis muscle (CALM) is an adductor of the arytenoid cartilages but is not directly involved in the pathogenesis of recurrent laryngeal neuropathy (RLN) as the abductor cricoarytenoideus dorsalis muscle (CADM) is. Nevertheless, the CALM is the first muscle to experience a neurogenic atrophy in the course of RLN and this feature explains its potential importance in RLN diagnosis. On 30 gelding and 30 female Standardbred horses weighing about 500 kg and aged between 3 and 9 years, an ultrasound examination of the larynx was performed in order to assess shape, size, and echogenicity of the CALMs. The mean …
Establishment And Biological Research Of The Jining Grey Goat Fibroblast Line, Chunyu Bai, Dianjun Wang, Xiaohua Su, Minghai Zhang, Weijun Guan, Yuehui Ma
Establishment And Biological Research Of The Jining Grey Goat Fibroblast Line, Chunyu Bai, Dianjun Wang, Xiaohua Su, Minghai Zhang, Weijun Guan, Yuehui Ma
Turkish Journal of Veterinary & Animal Sciences
Using Jining Grey goat ear marginal tissues as experimental materials, we succeeded in establishing a fibroblast cell bank, including 32 samples, by means of a primary explant and cryopreservation technique. The results from the biological analysis suggested that the population doubling time of the cell line was approximately 48 h. The diploid accounted for 98.35%, the isozyme analysis of the lactic dehydrogenase and malic dehydrogenase disproved cross contamination, and the results of the bacterium, fungi, virus, and mycoplasma detection tests were all negative. The transfection rates of 3 fluorescent protein genes were high, which supported the opinion that exogenous genes …
Effect Of Cold Storage Period On The Quality Of Ram Cauda Epididymal Spermatozoa Recovered Postmortem, Suhail Salam Mir, Farooz Ahmad Lone, Mohammad Zaffarullah Khan, Asloob Ahmad Malik, Rafiqul Islam, Khursheed Ahmad Sofi
Effect Of Cold Storage Period On The Quality Of Ram Cauda Epididymal Spermatozoa Recovered Postmortem, Suhail Salam Mir, Farooz Ahmad Lone, Mohammad Zaffarullah Khan, Asloob Ahmad Malik, Rafiqul Islam, Khursheed Ahmad Sofi
Turkish Journal of Veterinary & Animal Sciences
Postmortem spermatozoa recovery is an important tool for harvesting germplasm from genetically meritorious animals and endangered species. The principal motive of this study was to find out whether ram spermatozoa within epididymides kept at 4 °C for 48 h retain their quality in terms of progressive motility, viability, and acrosomal status. Twenty-four testicles with attached epididymides were collected with 8 samples each processed at 0, 24, and 48 h of storage. A good number of motile spermatozoa could be recovered from epididymides by incision method with up to 48 h of storage, although their quality declined significantly (P < 0.05) as postmortem storage time increased (motility: 83.33 ± 1.05%, 63.33 ± 2.47%, and 44.17 ± 1.53%; and epididymal sperm output (millions): 3500.00 ± 73.97, 1220.00 ± 1.01, and 666.67 ± 19.78 for 0 (control), 24, and 48 h, respectively). Viability and intact acrosomes (%) were also acceptable, although they decreased significantly with up to 24 h of storage. In conclusion, ram epididymides could be stored at 4 °C for 48 h when epididymal spermatozoa cannot be immediately harvested and cryopreserved.
Craniometric Analysis Of Early Medieval Horses Equus Przewalskii F. Caballus (Linnaeus, 1758) From Chosen Areas In Poland, Edyta Pasicka, Aleksander Chrószcz, Maciej Janeczek, Anna Mucha
Craniometric Analysis Of Early Medieval Horses Equus Przewalskii F. Caballus (Linnaeus, 1758) From Chosen Areas In Poland, Edyta Pasicka, Aleksander Chrószcz, Maciej Janeczek, Anna Mucha
Turkish Journal of Veterinary & Animal Sciences
These studies were carried out on 14 adult (9 males and 5 females) Equus przewalskii f. caballus (Linnaeus, 1758) horses, using both the skulls and mandibles. All of the material originated from 3 Polish archaeological sites that date back to the Early Medieval period. The most extensive craniometrical investigations consisted of 40 skull measurements and 16 mandible measurements. In some cases, the conditions of the artifacts narrowed the number of accessible osteometric points. The aim of this study was an estimation of the craniometric measurement differences and an examination of their statistical importance according to animal sex, age, and origin. …
Effects Of Dietary Inclusion Of Clinoptilolite In Colostrum And Milk On Certain Haematological Parameters Of Calves, Konstantinos Pourliotis, Maria Karatzia, Efterpi Christaki, Panagiotis Katsoulos, Harilaos Karatzias`
Effects Of Dietary Inclusion Of Clinoptilolite In Colostrum And Milk On Certain Haematological Parameters Of Calves, Konstantinos Pourliotis, Maria Karatzia, Efterpi Christaki, Panagiotis Katsoulos, Harilaos Karatzias`
Turkish Journal of Veterinary & Animal Sciences
The administration of a natural zeolite, clinoptilolite, in newborn calves via colostrum and milk has been proven to be beneficial in enhancing the intestinal absorption of immunoglobulins and in reducing the incidence and the severity of diarrhoea syndrome. The aim of this study was to investigate whether a 2-month-long supplementation at 2 levels (1 g/kg body weight (BW) and 2 g/kg BW) of clinoptilolite in the colostrum and milk of dairy calves had any effect on their haematological parameters. A total of 84 clinically healthy Holstein calves were assigned to 1 of 3 groups immediately after calving. Group A (n …
The Effects Of Prestorage Leukoreduction And Storage Duration On The In Vitro Quality Of Canine Packed Red Blood Cells, Eli̇f Ergül Eki̇z, Murat Arslan, İbrahi̇m Akyazi, Evren Eraslan Uygur, Güldal İnal Gülteki̇n, Mukaddes Özcan
The Effects Of Prestorage Leukoreduction And Storage Duration On The In Vitro Quality Of Canine Packed Red Blood Cells, Eli̇f Ergül Eki̇z, Murat Arslan, İbrahi̇m Akyazi, Evren Eraslan Uygur, Güldal İnal Gülteki̇n, Mukaddes Özcan
Turkish Journal of Veterinary & Animal Sciences
The effects of prestorage leukoreduction and storage duration on the in vitro quality parameters of canine packed red blood cells (pRBCs) stored in saline-adenine-glucose-mannitol (SAGM) were investigated. Hematological, biochemical, and morphological changes in filtered and unfiltered pRBCs were determined each week during 42 days of storage. All of the parameters changed significantly during storage. The effects of leukoreduction on leukocyte and erythrocyte count, packed cell volume, hemoglobin content, and erythrocyte morphology were significant. While supernatant K increased during storage, glucose, Cl, and 2,3-diphosphoglycerate (2,3-DPG) concentrations decreased. Filtered pRBCs had higher 2,3-DPG levels throughout storage than their unfiltered counterparts. It was …
Comparison Of Different Lactation Curve Models In Sahiwal Cows, Vilas Dongre, Ravindar Singh Gandhi, Avtar Singh
Comparison Of Different Lactation Curve Models In Sahiwal Cows, Vilas Dongre, Ravindar Singh Gandhi, Avtar Singh
Turkish Journal of Veterinary & Animal Sciences
The present investigation was carried out on 12,859 fortnightly test-day milk yield records of first lactation pertaining to 643 Sahiwal cows spread over a period of 49 years (1961-2009), maintained at the National Dairy Research Institute, Karnal, India. The comparison of 3 lactation curve models, i.e. the quadratic model, gamma-type function, and mixed log function, was done using fortnightly test-day milk yield records. The mixed log function was the best fit, with the highest (88.75%) coefficient of determination (R2 value) and the lowest (0.08 kg) root mean square error (RMSE) value, whereas the lowest (56.93%) R2 value was observed in …
Dietary Boron Intake Does Not Change The Ischemic Tolerance And Preconditioning Response In Isoproterenol-Induced Myocardial Injury In Healthy Rats, Mehmet Fati̇h Karakaş, Mustafa Kurt, Uğur Arslantaş, Göktürk İpek, Esra Karakaş, Emi̇ne Bi̇len, Hüsametti̇n Erdamar
Dietary Boron Intake Does Not Change The Ischemic Tolerance And Preconditioning Response In Isoproterenol-Induced Myocardial Injury In Healthy Rats, Mehmet Fati̇h Karakaş, Mustafa Kurt, Uğur Arslantaş, Göktürk İpek, Esra Karakaş, Emi̇ne Bi̇len, Hüsametti̇n Erdamar
Turkish Journal of Medical Sciences
Boron is important for many enzymes, most of which also have a role in the ischemic tolerance of the myocardium. We aimed to evaluate the influence of dietary boron intake on ischemic tolerance in a rat model. Materials and methods: Rats were divided into 3 groups according to the ischemia protocol: Sham (S) (n = 20 total), ischemia only (Isc-only) (n = 40 total), and remote ischemic preconditioning + ischemia (RIPC+Isc) (n = 40 total) groups. These 3 groups were further divided into 4 according to the amount of daily dietary boron (
Effects Of Lycopene On Plasma Glucose, Insulin Levels, Oxidative Stress, And Body Weights Of Streptozotocin-Induced Diabetic Rats, Muhsi̇n Aydin, Sefa Çeli̇k
Effects Of Lycopene On Plasma Glucose, Insulin Levels, Oxidative Stress, And Body Weights Of Streptozotocin-Induced Diabetic Rats, Muhsi̇n Aydin, Sefa Çeli̇k
Turkish Journal of Medical Sciences
To determine possible therapeutic effects of oral lycopene supplementation on plasma insulin levels, lipid peroxidation, blood glucose levels, and the antioxidant defense system of streptozotocin-induced diabetic rats. Materials and methods: Classical biochemical methods were used to determine plasma malondialdehyde (MDA), nitric oxide (NO), glutathione peroxidase (GSH-Px), catalase (CAT), superoxide dismutase (SOD), and glutathione (GSH) levels. Enzyme-linked immunosorbent assay was used to determine plasma insulin levels and reverse transcriptase-polymerase chain reaction was used to determine the levels of brain antioxidant enzymes (SOD, CAT, and GSH-Px). Results: It was found that the diabetes-related increase in blood glucose levels was reduced by supplementation …
Effect Of Intravitreal Octreotide Acetate Injection On Retinal Neovascularization, Morphology, And Apoptotic Cell Death In An Oxygen-Induced Retinopathy Mouse Model, Fatma Seli̇n Kaya, İmren Akkoyun, Asuman Ni̇han Haberal Reyhan, Atti̇la Dağdevi̇ren, Gürsel Yilmaz, Si̇bel Oto, Yonca Akova
Effect Of Intravitreal Octreotide Acetate Injection On Retinal Neovascularization, Morphology, And Apoptotic Cell Death In An Oxygen-Induced Retinopathy Mouse Model, Fatma Seli̇n Kaya, İmren Akkoyun, Asuman Ni̇han Haberal Reyhan, Atti̇la Dağdevi̇ren, Gürsel Yilmaz, Si̇bel Oto, Yonca Akova
Turkish Journal of Medical Sciences
To investigate the effect of octreotide acetate on neovascularization, retinal structures, and apoptotic cell death in an oxygen-induced retinopathy (OIR) mouse model. Materials and methods: A total of 26 C57BL/6J mice were exposed to 75 ± 2% oxygen from postnatal day 7 to 12. On day 12, 12 mice (group C) were injected with 0.1 µg intravitreal octreotide acetate (IVOA) and 14 mice (group D) were injected with 0.05 µg IVOA, in the right eye. The contralateral eyes were injected with 1 µL isotonic saline (control group, group B). Four mice were used as negative controls (group A). Neovascularization was …
Electrical Fatalities In Ankara Over 11 Years, Ramazan Akçan, Emre Karacaoğlu, Alper Keten, Aysun Balseven Odabaşi, Çi̇ğdem Kanburoğlu, Ali̇ Riza Tümer, Hani̇fe Alkurt-Alkan
Electrical Fatalities In Ankara Over 11 Years, Ramazan Akçan, Emre Karacaoğlu, Alper Keten, Aysun Balseven Odabaşi, Çi̇ğdem Kanburoğlu, Ali̇ Riza Tümer, Hani̇fe Alkurt-Alkan
Turkish Journal of Medical Sciences
Electrical injuries are still responsible for significant morbidity and mortality; however, they are generally preventable with simple safety measures. This study Abstracts to determine the general features of electrical fatalities, and to draw attention of health professionals towards such preventable deaths. Materials and methods: A retrospective evaluation of records of electrocution-related deaths in Ankara, Turkey, was conducted over 11 years (1998-2008). Results: Out of 12,263 autopsy cases, 100 (0.8%) were secondary to electrocution. Most of the victims were male (n = 94; 94%) while only 6 were female. Victims’ age ranged from 1 year to 76 years, with a mean …
The Effect Of Knk437, A Heat Shock Protein Inhibitor, On Angiogenesis Of Endothelial Cells, Emel Şahi̇n, Mehmet Şahi̇n, Saadet Gümüşlü
The Effect Of Knk437, A Heat Shock Protein Inhibitor, On Angiogenesis Of Endothelial Cells, Emel Şahi̇n, Mehmet Şahi̇n, Saadet Gümüşlü
Turkish Journal of Medical Sciences
Aim: Hyperthermia is an effective therapy for cancer and tumor angiogenesis. However, the development of thermotolerance is an important problem. We aimed to investigate the effects of KNK437 and quercetin on angiogenesis and thermotolerance in endothelial cells (ECs). Materials and methods: ECs were grown in EGM-2 medium. ECs were preincubated with KNK437 or quercetin and then treated with single and fractionated hyperthermia. Tube formation assay on Matrigel Matrix was performed in these cells to investigate angiogenesis. Results: Tube formation was suppressed in cells that were treated with KNK437 and quercetin at 37 °C. Single hyperthermia (45 °C for 1 h) …
Biochemical And Structural Changes Of The Kidney In Mice Exposed To Phenol, Zahra Tootian, Ali Louei Monfared, Simin Fazelipour, Mohammad Taghi Shybani, Fatemeh Rouhollah, Farhang Sasani, Ebrahim Molaemi
Biochemical And Structural Changes Of The Kidney In Mice Exposed To Phenol, Zahra Tootian, Ali Louei Monfared, Simin Fazelipour, Mohammad Taghi Shybani, Fatemeh Rouhollah, Farhang Sasani, Ebrahim Molaemi
Turkish Journal of Medical Sciences
Aim: To investigate the histology and function of the kidney in mice exposed to different concentrations of phenol through the gavage method for 10 consecutive days. Materials and methods: Forty female BALB/c mice were selected and randomly divided into 1 control group and 3 experimental groups. The control group was administered distilled water through the gavage method, while the experimental groups received daily doses of 80, 180, and 320 mg/kg of phenol, respectively. After 10 days, blood samples were collected and the sera were analyzed biochemically. Renal tissue samples were also taken and histopathological changes of the kidneys were examined …
Effect Of Prenatal Exposure To Cigarette Smoke On The Conduction Of Sensory Nerve Fibers In The Rat, Jumah Shakhanbeh
Effect Of Prenatal Exposure To Cigarette Smoke On The Conduction Of Sensory Nerve Fibers In The Rat, Jumah Shakhanbeh
Turkish Journal of Medical Sciences
Aim: To investigate the effect of prenatal exposure to cigarette smoke (CS) on the conduction of sensory nerve fibers in the adult rat offspring. Materials and methods: Pregnant rats were exposed to CS by inhalation during the gestation period. The saphenous nerve in the adult offspring was exposed in vivo, and the conduction parameters of the threshold, maximum strength of stimulation, conduction velocity, and amplitude of compound action potentials (CAPs) of A\alpha\beta-, A\delta-, and C-fibers were examined. Results: Prenatal exposure to CS induced significant reduction (P < 0.005) in the peak amplitude of CAPs of A\alpha\beta- and A\delta-fibers. The conduction velocity of A\alpha\beta-fibers and C-fibers was significantly (P < 0.025-0.05) increased after prenatal exposure to CS. Conclusion: Prenatal exposure to CS attenuates the conduction of sensory nerve fibers in the rat saphenous nerve.
Plasma Levels Of Il-6 And Tnf-\Alpha In Patients With Esophageal Cancer, Yener Aydin, İbrahi̇m Kaplan, Yusuf Bi̇len, Çağlar Bulut, Fatma Genç, Ati̇la Türkyilmaz, Ati̇la Eroğlu
Plasma Levels Of Il-6 And Tnf-\Alpha In Patients With Esophageal Cancer, Yener Aydin, İbrahi̇m Kaplan, Yusuf Bi̇len, Çağlar Bulut, Fatma Genç, Ati̇la Türkyilmaz, Ati̇la Eroğlu
Turkish Journal of Medical Sciences
Cytokines are multifunctional polypeptides synthesized in various cell types. Interleukin-6 (IL-6) and tumor necrosis factor-\alpha (TNF-\alpha) are cytokines that have important roles in cancer pathogenesis. In this study, we investigated the plasma levels of IL-6 and TNF-\alpha in patients with esophageal cancer. Materials and methods: Forty-three esophageal cancer patients (24 females and 19 males) who were newly diagnosed and had not yet undergone operation participated in the study. The patients' average age was 61.03 ± 12.4 years. The control group, on the other hand, comprised 43 healthy individuals (22 males and 21 females) with an average age of 56 ± …
Evaluation Of Vitamin B-12 Level In Middle-Aged Obese Women With Metabolic And Non-Metabolic Syndrome: Case-Control Study, Davut Baltaci, Ali̇ Kutlucan, Serkan Öztürk, İsmai̇l Karabulut, Hayri̇ye Ak Yildirim, Ahmet Çeler, Gökhan Celbek, İsmai̇l Hamdi̇ Kara
Evaluation Of Vitamin B-12 Level In Middle-Aged Obese Women With Metabolic And Non-Metabolic Syndrome: Case-Control Study, Davut Baltaci, Ali̇ Kutlucan, Serkan Öztürk, İsmai̇l Karabulut, Hayri̇ye Ak Yildirim, Ahmet Çeler, Gökhan Celbek, İsmai̇l Hamdi̇ Kara
Turkish Journal of Medical Sciences
To investigate the correlation between vitamin B12 and body mass index (BMI) along with insulin resistance (IR) in middle-aged obese women. Materials and methods: The study was designed as a case-control study. The study group included middle-aged obese women and the control group included aged-matched lean women. Weight, height, and hip and waist circumferences were measured. Biochemical parameters such as fasting and postprandial glucose, vitamin B12 and folic acid levels, and lipid profiles were assayed. Results: Enrolled in the study were 116 middle-aged obese and 103 aged-matched healthy lean women. The vitamin B12 level of the obese women was significantly …
Evaluation Of The Antibacterial Activity Of Zataria Multiflora Boiss., Rhus Coriaria L. (Sumac), Mentha Piperita L., And Ocimum Basilicum L. Extracts On Brucella Strains Isolated From Brucellosis Patients, Yousef Motaharinia, Mohammad Ali Rezaee, Mohammad Saleh Hazhir, Farid Zandi, Reza Shapouri, Mohammad Saied Hakhamaneshi, Ahmad Rashidi, Mohammad Reza Rahmani
Evaluation Of The Antibacterial Activity Of Zataria Multiflora Boiss., Rhus Coriaria L. (Sumac), Mentha Piperita L., And Ocimum Basilicum L. Extracts On Brucella Strains Isolated From Brucellosis Patients, Yousef Motaharinia, Mohammad Ali Rezaee, Mohammad Saleh Hazhir, Farid Zandi, Reza Shapouri, Mohammad Saied Hakhamaneshi, Ahmad Rashidi, Mohammad Reza Rahmani
Turkish Journal of Medical Sciences
Since brucellosis has been called a chronic illness and treatment of patients infected with this bacterium has not been successful, the present study aim ed to evaluate the effects of several medicinal plant extracts on clinical Brucella strains. Materials and methods: First, Brucella strains were isolated from brucellosis patients. Then an antibiotic resistance assay was performed for these strains, while the antibacterial activity of the above-mentioned extracts was evaluated. Results: After performing accurate evaluations, the obtained results showed that all of the isolated Brucella strains were sensitive to tetracycline, doxycycline, and gentamicin, and the rates of antibiotic resistance to rifampin …
Antinociceptive Activity Of Some Scorzonera L. Species, Özlem Bahadir Acikara, Hayri̇ye Gülçi̇n Saltan, Hanefi̇ Özbek
Antinociceptive Activity Of Some Scorzonera L. Species, Özlem Bahadir Acikara, Hayri̇ye Gülçi̇n Saltan, Hanefi̇ Özbek
Turkish Journal of Medical Sciences
Scorzonera species are mainly used to relieve pain in Turkish traditional medicine. The roots of Scorzonera latifolia (Fisch. & Mey) DC., S. tomentosa L., S. suberosa C.Koch subsp. suberosa, and S. mollis M.Bieb. subsp. szowitzii collected from different regions of Anatolia, and yakı sakızı, which is prepared by drying the latex obtained from the roots of Scorzonera latifolia, were evaluated for their antinociceptive activities. Materials and methods: For antinociceptive evaluation, Scorzonera latifolia (Fisch. & Mey) DC., S. tomentosa L., S. suberosa C.Koch subsp. suberosa, S. mollis M.Bieb. subsp. szowitzii, and yakı sakızı were tested on mice, and acetic acid-induced writhing …
Early Oxidative Status In Adult Patients With Isolated Traumatic Brain Injury, Özgür Söğüt, Hali̇l Kaya, Mehmet Tahi̇r Gökdemi̇r, Leyla Solduk, Mehmet Aki̇f Dokuzoğlu, Mustafa Burak Sayhan, Atilhan Kaya, Abdürrahi̇m Koçyi̇ği̇t
Early Oxidative Status In Adult Patients With Isolated Traumatic Brain Injury, Özgür Söğüt, Hali̇l Kaya, Mehmet Tahi̇r Gökdemi̇r, Leyla Solduk, Mehmet Aki̇f Dokuzoğlu, Mustafa Burak Sayhan, Atilhan Kaya, Abdürrahi̇m Koçyi̇ği̇t
Turkish Journal of Medical Sciences
To investigate oxidative and antioxidative status, as well as the Glasgow Coma Scale (GCS) and Revised Trauma Score (RTS), reflecting injury severity and neurological outcome during the early posttraumatic period in patients with isolated traumatic brain injury (TBI). Materials and methods: Fifty-one adult patients with TBI and 45 eligible healthy volunteers as control subjects were enrolled. Plasma total oxidant status (TOS), total antioxidant status (TAS), and the oxidative stress index (OSI) were calculated as biomarkers of early oxidative changes in serum using a novel automated method. Results: TOS levels and OSI values were significantly higher in nonsurvivors compared with those …
Is Grayanotoxin Directly Responsible For Mad Honey Poisoning-Associated Seizures, Abdülkadi̇r Gündüz, Murat Aydin, Metehan Akça, Süha Türkmen, Süleyman Türedi̇, Umut Eryi̇ği̇t, Ali̇ Cansu, Mehmet Yildirim
Is Grayanotoxin Directly Responsible For Mad Honey Poisoning-Associated Seizures, Abdülkadi̇r Gündüz, Murat Aydin, Metehan Akça, Süha Türkmen, Süleyman Türedi̇, Umut Eryi̇ği̇t, Ali̇ Cansu, Mehmet Yildirim
Turkish Journal of Medical Sciences
The aim of this study was to investigate the effects of grayanotoxin on epileptiform activity in rats. Materials and methods: Forty-two male Sprague Dawley rats were equally divided into 1 of 7 groups. Thirty minutes after induction of epileptiform activity induced by penicillin injection, 0.5, 1, 2, 4, or 8 µg of grayanotoxin-III was intracerebroventricularly administered. Epileptiform activity spike frequency and amplitude were converted into numerical data using software following the experiment. Results: Our results show that grayanotoxin reduces epileptiform spike frequency and amplitude in a dose-dependent manner. Five minutes postinjection, grayanotoxin significantly reduced epileptiform activity, especially at higher doses. …
High Cerebrospinal Fluid Protein Level In West Nile Virus Ncephalitis: Report Of Five Cases, Oğuz Karabay, Nazan Tuna, Mehmet Yahyaoğlu, Gökçen Kayan
High Cerebrospinal Fluid Protein Level In West Nile Virus Ncephalitis: Report Of Five Cases, Oğuz Karabay, Nazan Tuna, Mehmet Yahyaoğlu, Gökçen Kayan
Turkish Journal of Medical Sciences
An outbreak of West Nile virus (WNV) occurred in Greece, Russia, and Turkey in 2010. We diagnosed 5 WNV encephalitis patients, who presented with high cerebrospinal fluid (CSF) protein level and encephalitis relevant symptoms in the last days of summer or in the first days of autumn. Here, we aimed to present a retrospective analysis of 5 WNV encephalitis cases in Turkey in terms of their clinical and laboratory findings.
Histopathological Effects Of S. Xylosus Peptidoglycan In Comparison To E. Coli Lipopolysaccharide In The Urinary Tract Of Mice, Harith Jabbar Fahad Al-Mathkhury, May Talib Flaih, Hiba Khalil Tawfiq
Histopathological Effects Of S. Xylosus Peptidoglycan In Comparison To E. Coli Lipopolysaccharide In The Urinary Tract Of Mice, Harith Jabbar Fahad Al-Mathkhury, May Talib Flaih, Hiba Khalil Tawfiq
Turkish Journal of Medical Sciences
The present work, among other previous studies done in our lab, aimed to highlight the histopathological effect of S. xylosus peptidoglycan in comparison to LPS of E. coli. Materials and methods: One hundred and fifty urine specimens were collected from urinary tract infection patients visiting Baghdad hospitals. The histopathological effects of S. xylosus S24 peptidoglycan was studied in the urinary tract of female mice by injecting 5 animal groups at the following concentrations: 1000, 2000, 3000, 4000, and 5000 µg/mL. Another 5 groups were injected with 10, 25, 50, 75, and 100 ng/mL of E. coli (serotype 0128:B12) LPS. Results: …
Radioimmunotherapy Of Mice Bearing Breast Tumors With ^{177}Lu-Labeled Trastuzumab, Samira Rasaneh, Hossein Rajabi, Shahram Akhlaghpoor, Shahab Sheybani
Radioimmunotherapy Of Mice Bearing Breast Tumors With ^{177}Lu-Labeled Trastuzumab, Samira Rasaneh, Hossein Rajabi, Shahram Akhlaghpoor, Shahab Sheybani
Turkish Journal of Medical Sciences
In the present study, we investigated the therapeutic efficacy of trastuzumab labeled with lutetium-177 (^{177}Lu) in mice bearing breast tumors. Materials and methods: Trastuzumab was labeled with ^{177}Lu via DOTA as a chelator. In vitro and in vivo quality control tests of incorporated activity, immunoreactivity, stability of ^{177}Lu-trastuzumab, biodistribution, and imaging studies were performed. Therapeutic efficacy and dosimetry studies were carried out in mice with breast tumors. Results: The good in vitro and in vivo quality control results suggested that ^{177}Lu-trastuzumab could be used as a radioimmunotherapy agent. Reductions of 81% and 98% in the mean tumor volume for the …
Cerebral Blood Flow During Single Lung Ventilation, Mehmet Muharrem Erol, Si̇bel Kul, Ayşegül Cansu, Celal Teki̇nbaş, Engi̇n Ertürk, Murat Topbaş
Cerebral Blood Flow During Single Lung Ventilation, Mehmet Muharrem Erol, Si̇bel Kul, Ayşegül Cansu, Celal Teki̇nbaş, Engi̇n Ertürk, Murat Topbaş
Turkish Journal of Medical Sciences
Our aim was to show the effect of one-lung ventilation (OLV) on cerebral blood flow (CBF) by measuring carotid blood flow. This technique has been the subject of experimental and clinical studies. Materials and methods: Carotid doppler flows were measured at 4 different times. Peak systolic velocity (PSV) and end diastolic velocity (EDV) were measured and pulsatility index (PI) and resistive index (RI) calculated. Results: There were no significant changes in PSV, PI, RI, or flow volume in the normal or diseased sides at repeated measures (P > 0.05).There was no significant difference between the flow velocities, PIs, RIs, or flow …