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The Efficacy Of Oral Ribavirin On Clinical And Laboratory Parameters Incrimean?Congo Hemorrhagic Fever: An Observational Study From Turkey*, Günay Ertem, Meli̇ha Çağla Sönmezer, Fati̇h Temoçi̇n, Çi̇ğdem Ataman Hati̇poğlu, Necla Tülek, Behi̇ç Oral
The Efficacy Of Oral Ribavirin On Clinical And Laboratory Parameters Incrimean?Congo Hemorrhagic Fever: An Observational Study From Turkey*, Günay Ertem, Meli̇ha Çağla Sönmezer, Fati̇h Temoçi̇n, Çi̇ğdem Ataman Hati̇poğlu, Necla Tülek, Behi̇ç Oral
Turkish Journal of Medical Sciences
Background/aim: In this observational study, the effects of oral ribavirin on clinical and laboratory parameters and blood products use in patients with Crimean-Congo hemorrhagic fever (CCHF) were evaluated. Materials and methods: CCHF patients (n = 100) who were hospitalized between 2007 and 2010 were included. Oral ribavirin was administered to 56 patients with symptom duration less than 5 days. Forty-four patients did not receive ribavirin (control group). The patients that received ribavirin in the first 3 days following the initiation of symptoms were designated as Group 1 (n = 29) and the others were designated as Group 2. Results: Ribavirin-treated …
Genotypic Analysis Of Escherichia Coli Strains That Cause Urosepsis In The Aegean Region, Betül Gi̇ray, Füsun Bahri̇ye Uçar, Sabi̇re Şöhret Aydemi̇r
Genotypic Analysis Of Escherichia Coli Strains That Cause Urosepsis In The Aegean Region, Betül Gi̇ray, Füsun Bahri̇ye Uçar, Sabi̇re Şöhret Aydemi̇r
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to characterize strains genotypically, to determine their phylogenetic relationships, to investigate the presence of the papG gene, and to compare their antibiotic susceptibility test results. Materials and methods: Seventy pathogenic E. coli strains were isolated from both urine and blood cultures of patients with the preliminary diagnosis of urosepsis who were referred to the Ege University Faculty of Medicine, Bacteriology Laboratory of Medical Microbiology Department in İzmir. All of these strains were examined for the papG gene and phylogenetic groups with the multiplex polymerase chain reaction technique. Pulsed-field gel electrophoresis and multilocus sequence …
The Protective Effects Of Hydrogen On Ho-1 Expression In The Brainafter Focal Cerebral Ischemia Reperfusion In Rats, Xifeng Wang, Lianshuang Zhang, Wei Zhao, Tongshen Liu
The Protective Effects Of Hydrogen On Ho-1 Expression In The Brainafter Focal Cerebral Ischemia Reperfusion In Rats, Xifeng Wang, Lianshuang Zhang, Wei Zhao, Tongshen Liu
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to investigate whether a hydrogen administration can produce neuroprotective effects after brain ischemia reperfusion in rats. Materials and methods: A brain ischemia reperfusion injury was induced by a 2-h left middle cerebral artery occlusion (MCAO) using an intraluminal filament, followed by 46 h of reperfusion. A hydrogen-rich saline (1 mL/kg body weight i.p.) was administered at the beginning of reperfusion. Saline (1 mL/kg)-treated animals were used as the control. Sham-operated animals were also used. Subsequently, 48 h after the MCAO, histological alternations, heme oxygenase-1 (HO-1) expression, and levels of malondialdehyde (MDA) and superoxide …
Effect Of Methylprednisolone Injection On Interleukin-4 And Interferon-Gamma Expression Following Hepatitis B Vaccination In Mice, Peter Ughachukwu, Paul Okonkwo, Prince Unekwe, John Ogamba
Effect Of Methylprednisolone Injection On Interleukin-4 And Interferon-Gamma Expression Following Hepatitis B Vaccination In Mice, Peter Ughachukwu, Paul Okonkwo, Prince Unekwe, John Ogamba
Turkish Journal of Medical Sciences
Background/aim: The prevalence of hepatitis B infection is high worldwide with liver cirrhosis and hepatocellular carcinoma as important complications. Immunosuppression, especially from corticosteroids, is often cited as a cause of poor immune response and there is documented evidence of irrational administration of glucocorticoids to children and adults. Decreased expression of interleukin-4 and interferon-gamma is an indication of poor humoral and cellular immune responses, respectively. Therefore, we decided to find out if methylprednisolone injection decreases interleukin-4 and interferon-gamma expression following hepatitis B vaccination in mice. Materials and methods: Mice were randomly divided into 2 groups. Daily intramuscular injections of methylprednisolone (15 …
Analysis Of Diabetes-Related Cerebellar Changes In Streptozotocin-Induced Diabetic Rats, Nuri̇ye Güzi̇n Özdemi̇r, Feray Akbaş, Tuğba Koti̇l, Adem Yilmaz
Analysis Of Diabetes-Related Cerebellar Changes In Streptozotocin-Induced Diabetic Rats, Nuri̇ye Güzi̇n Özdemi̇r, Feray Akbaş, Tuğba Koti̇l, Adem Yilmaz
Turkish Journal of Medical Sciences
Background/aim: Diabetic peripheral neuropathy has been extensively studied and reported, but the number of studies that have investigated diabetes-related changes in the central nervous system are limited, with even fewer studies on the cerebellum. The aim of this experimental study was to perform a histologic analysis of the diabetes-related changes in the cerebellums of diabetic rats. Materials and methods: Twenty Sprague Dawley rats weighing between 200 and 220 g were included in the study. Diabetes was induced in 14 of these rats by a single intraperitoneal injection of 65 mg/kg streptozotocin dissolved in saline, while 6 animals constituted the control …
Neuroprotective Effects Of Bone Marrow-Derived Mesenchymal Stem Cellsand Conditioned Medium In Mechanically Injured Neuroblastoma Cells, Mesut Mete, Işil Aydemi̇r, Ülkü Ünlü Ünsal, Yusuf Kurtuluş Duransoy, Mehmet İbrahi̇m Tuğlu, Mehmet Selçuki̇
Neuroprotective Effects Of Bone Marrow-Derived Mesenchymal Stem Cellsand Conditioned Medium In Mechanically Injured Neuroblastoma Cells, Mesut Mete, Işil Aydemi̇r, Ülkü Ünlü Ünsal, Yusuf Kurtuluş Duransoy, Mehmet İbrahi̇m Tuğlu, Mehmet Selçuki̇
Turkish Journal of Medical Sciences
Background/aim: Bone marrow-derived mesenchymal stem cells (BMSCs) possess self-renewal characteristics that distinguish them from other cell types. Recent studies have focused on the effects of conditioned medium (CM) that includes the extracellular matrix. Here we examined the neuroprotective effects of BMSCs and CM on damaged neuroblastoma cells. Materials and methods: The cells were divided into five groups: 1) healthy controls, 2) damaged cells alone, 3) damaged cells treated with BMSCs, 4) damaged cells treated with CM, and 5) damaged cells treated with both BMSCs and CM. Neuroprotective effects were then evaluated based upon the levels of oxidative stress, antitransforming growth …
An Hf/Uhf Dual Mode Rfid Transponder Antenna And Hf Range Extension Using Uhf Wireless Power Transmission, Mustafa Murat Bi̇lgi̇ç, Korkut Yeği̇n
An Hf/Uhf Dual Mode Rfid Transponder Antenna And Hf Range Extension Using Uhf Wireless Power Transmission, Mustafa Murat Bi̇lgi̇ç, Korkut Yeği̇n
Turkish Journal of Electrical Engineering and Computer Sciences
An HF/UHF compatible RFID transponder antenna is designed, simulated, and measured for dual band operation and HF range extension. A dual mode compatible RFID transponder antenna has the benefits of each mode and eliminates the disadvantages of single mode operation. One of the major drawbacks of UHF antennas is their poor performance when the tag is placed on or near metallic objects. To overcome this shortcoming, two-layer substrate with degenerate grounded is used and a 4-turn spiral antenna is placed on the top and bottom parts of the substrate for HF operation. The co-existence of both antennas affects standalone performances …
Design Of A Low-Power, Low-Cost Uhf Rfid Reader Module, Özgür Bostan, Hüseyi̇n Ulvi̇ Aydoğmuş, Serkan Topaloğlu
Design Of A Low-Power, Low-Cost Uhf Rfid Reader Module, Özgür Bostan, Hüseyi̇n Ulvi̇ Aydoğmuş, Serkan Topaloğlu
Turkish Journal of Electrical Engineering and Computer Sciences
No abstract provided.
Design And Implementation Of A New Manet Simulator Model For Aodv Simulation, Si̇nan Tüncel, Hüseyi̇n Eki̇z, Ahmet Zengi̇n
Design And Implementation Of A New Manet Simulator Model For Aodv Simulation, Si̇nan Tüncel, Hüseyi̇n Eki̇z, Ahmet Zengi̇n
Turkish Journal of Electrical Engineering and Computer Sciences
No abstract provided.
A New Abc-Based Multiobjective Optimization Algorithm With An Improvement Approach (Ibmo: Improved Bee Colony Algorithm For Multiobjective Optimization), Tahi̇r Sağ, Mehmet Çunkaş
A New Abc-Based Multiobjective Optimization Algorithm With An Improvement Approach (Ibmo: Improved Bee Colony Algorithm For Multiobjective Optimization), Tahi̇r Sağ, Mehmet Çunkaş
Turkish Journal of Electrical Engineering and Computer Sciences
No abstract provided.
Determination Of Forage Quality By Near-Infrared Reflectance Spectroscopy In Soybean, Sovetgul Asekova, Sang-Ik Han, Hong-Jib Choi, Sang-Jo Park, Dong-Hyun Shin, Chan-Ho Kwon, J. Grover Shannon, Jeong Dong Lee
Determination Of Forage Quality By Near-Infrared Reflectance Spectroscopy In Soybean, Sovetgul Asekova, Sang-Ik Han, Hong-Jib Choi, Sang-Jo Park, Dong-Hyun Shin, Chan-Ho Kwon, J. Grover Shannon, Jeong Dong Lee
Turkish Journal of Agriculture and Forestry
Soybeans have been a favored livestock forage for centuries. However, only a few studies have been conducted to estimate the forage quality of soybean by near-infrared reflectance spectroscopy (NIRS). In this study, 353 forage soybean samples were used to develop near-infrared reflectance (NIR) equations to estimate four forage quality parameters: crude protein (CP), crude fat (CF), neutral detergent fiber (NDF), and acid detergent fiber (ADF). Samples included 181 recombinant inbred lines derived from PI 483463 (G. Soja) × Hutcheson (G. Max), 104 cultivated soybeans (G. Max), and 68 wild soybeans (G. Soja). Two NIR equations developed for CP and CF …
Cancer Stem Cells: Lessons Learned From The Leukemic Stem Cells, Ayten Kandi̇lci̇
Cancer Stem Cells: Lessons Learned From The Leukemic Stem Cells, Ayten Kandi̇lci̇
Turkish Journal of Biology
Cancer is the second cause of death in Turkey and the frequency of cancer deaths increased from 12% in 2002 to 21% in 2009 ( Özkan et al., 2013). To win the war on cancer, we certainly need to apply well-planned prevention policies, given that it is caused mostly by environmental factors, and to develop more effective therapies. To achieve a cure for the disease, it is crucial to understand the cellular and molecular mechanisms leading to cancer and to therapeutically target all the factors playing a role in the initiation, progression, maintenance, and relapse of the disease, preferably in …
Pluripotent Stem Cells And Their Use In Hearing Loss, Ahmet Hamdi̇ Kepekçi̇, Okan Özgür Özturan, Mustafa Yavuz Köker
Pluripotent Stem Cells And Their Use In Hearing Loss, Ahmet Hamdi̇ Kepekçi̇, Okan Özgür Özturan, Mustafa Yavuz Köker
Turkish Journal of Biology
Throughout its half a century of development, stem cell research has included two main fields: embryonic stem (ES) cell research and the reprogramming of body somatic cells. In the present review we focused on stem cell reprogramming and its relation with otolaryngology. The human body somatic cells are transformed into pluripotent cells by three basic methods: the somatic nuclear transfer method, the somatic cell fusion method (getting cellular pluripotent capacity in cellular reprogramming), and by transcription factors influencing the body somatic cells to generate reprogrammed induced pluripotent stem (iPS) cells. ES cells and iPS cells have pluripotency and differentiate into …
Limbal Stem Cell Deficiency: Special Focus On Tracking Limbal Stem Cells, Santhosh Kacham, Bhaskar Birru, Sreenivasa Rao Parcha, Ramaraju Baadhe
Limbal Stem Cell Deficiency: Special Focus On Tracking Limbal Stem Cells, Santhosh Kacham, Bhaskar Birru, Sreenivasa Rao Parcha, Ramaraju Baadhe
Turkish Journal of Biology
The cornea, the transparent part of the eye that helps in the formation of images, has multiple layers. Among them, the superficial epithelial layer is protected and maintained homeostatically by the limbus, located in the periphery of the cornea. Limbal stem cells are located at the basal layer of the limbus and the loss of these cells is called limbal stem cell deficiency (LSCD). LSCD is characterized by corneal vascularization, inflammation, and conjunctivalization, which ultimately lead to blindness. Several clinical transplantation procedures used for the treatment of LSCD are cultivated limbal epithelial transplantation, simple limbal epithelial transplantation, and cultured oral …
Analysis Of Global Micrornaome Profiles Of Caenorhabditis Elegans Oocytes And Early Embryos, Selen Güçlü Durgun, Ahmet Raşi̇t Öztürk, Arzu Atalay
Analysis Of Global Micrornaome Profiles Of Caenorhabditis Elegans Oocytes And Early Embryos, Selen Güçlü Durgun, Ahmet Raşi̇t Öztürk, Arzu Atalay
Turkish Journal of Biology
One of the most complex cell transformations in biology is the remodeling of a fertilized oocyte into a totipotent zygote. There is no transcription during this event, and therefore mRNAs and proteins accumulated in the oocyte during oogenesis are utilized until zygotic genome activation. In order to differentiate into somatic cells, the embryo must erase the totipotency signature coming from the oocyte cytoplasm in the somatic blastomeres. In this study, the microRNAome profiles of oocytes and early embryos before and after zygotic genome activation were identified. By using next-generation high-throughput pyrosequencing and miRNA microarray techniques, miRNAome profiles of Caenorhabditis elegans …
Genetic Diversity And Crown Rust Resistance Of Oat Landracesfrom Various Locations Throughout Turkey, Zi̇ya Dumlupinar, Eric N. Jellen, John Michael Bonman, Eric W. Jackson
Genetic Diversity And Crown Rust Resistance Of Oat Landracesfrom Various Locations Throughout Turkey, Zi̇ya Dumlupinar, Eric N. Jellen, John Michael Bonman, Eric W. Jackson
Turkish Journal of Agriculture and Forestry
A diversity study was carried out to genetically characterize 375 oat landraces (Avena sativa L. And Avena byzantina K.Koch) collected from Turkey and preserved in different gene banks. New assays interrogating oat-based microsatellite and single nucleotide polymorphism loci were used to characterize the landraces. The assays interrogated 176 alleles at 68 loci with an average of 4.5 alleles per locus. The polymorphism information content of the simple sequence repeats was relatively high with a mean value of 0.76. The first two principal components from the principal component analysis (PCA) separated two groups of accessions and explained 9.3% of the variation …
Inheritance Of Fuzz And Lint Fiber Initiation Of Cotton (Gossypium Hirsutum L.), Adem Bardak, Yüksel Bölek
Inheritance Of Fuzz And Lint Fiber Initiation Of Cotton (Gossypium Hirsutum L.), Adem Bardak, Yüksel Bölek
Turkish Journal of Agriculture and Forestry
Fibers of cultivated cotton are classified into two types, lint and fuzz. Fuzzless seeds are cotton seeds lacking fuzz on almost the whole surface of the seed except for small amounts of fuzz at the micropylar or chalazal regions. Fuzzless seeds provide a number of advantages such as avoiding delintation processes and increasing the quality of feed rations. Therefore, it is important to develop varieties having seeds without fuzz but with high fiber ratios. This study, in which three different F2 populations have been developed by using three distinct genotypes as parents, was conducted to investigate the quantitative inheritance of …
Cadmium Contents Of Soils And Durum And Bread Wheats On Harran Plain, Southeast Turkey, Asuman Yanardağ, Ahmet Ruhi Mermut, Angel Faz Cano, Dora Maria Carmona Garces, İbrahi̇m Hali̇l Yanardağ
Cadmium Contents Of Soils And Durum And Bread Wheats On Harran Plain, Southeast Turkey, Asuman Yanardağ, Ahmet Ruhi Mermut, Angel Faz Cano, Dora Maria Carmona Garces, İbrahi̇m Hali̇l Yanardağ
Turkish Journal of Agriculture and Forestry
Durum wheat (Triticum turgidum durum (Desf.) Husn.) is produced on a large scale in Turkey, northern Syria, Kazakhstan, Iran, southern Europe, and North America, and is widely used for making spaghetti, noodles, couscous, and flatbreads. Uptake of Cd by durum wheat species is well known. The objectives of this study were to determine the cadmium (Cd) level of the soils and durum and bread wheat grown on Harran Plain, southeast Turkey, and evaluate it in terms of food safety. Soil samples were taken from 16 selected grains, leaves, and roots of durum and bread wheats for analyses. The total Cd …
The Effects Of Different Nitrogen And Phosphorus Doses On Essentialoil Components Of Some Mentha Genotypes, Meryem Yeşi̇l, Kemaletti̇n Kara
The Effects Of Different Nitrogen And Phosphorus Doses On Essentialoil Components Of Some Mentha Genotypes, Meryem Yeşi̇l, Kemaletti̇n Kara
Turkish Journal of Agriculture and Forestry
The present study was conducted in Erzurum during the years 2010 and 2011 to determine the effects of different nitrogen and phosphorus doses on essential oil components of spearmint genotypes (Mentha spicata L. and Mentha villoso-nervata Opiz.). Two genotypes of Mentha spicata (genotypes 2 and 6) and one genotype of Mentha villoso-nervata (genotype 4) were tested under three nitrogen and phosphorus doses (0, 50, and 100 kg/ha) in a randomized complete block design with three replications. Essential oil components of the genotypes were determined and subjected to variance analysis. Effects of experimental year and nitrogen and phosphorus doses on investigated …
Effect Of The Ethylene Inhibitors Silver Nitrate, Silver Sulfate, And Cobalt Chloride On Micropropagation And Biochemical Parameters In The Cherryrootstocks Cab-6p And Gisela 6, Virginia Sarropoulou, Kortessa Dimassi-Theriou, Ioannis Therios
Effect Of The Ethylene Inhibitors Silver Nitrate, Silver Sulfate, And Cobalt Chloride On Micropropagation And Biochemical Parameters In The Cherryrootstocks Cab-6p And Gisela 6, Virginia Sarropoulou, Kortessa Dimassi-Theriou, Ioannis Therios
Turkish Journal of Biology
In the present study, the effects of three ethylene inhibitors, silver nitrate (AgNO3), silver sulfate (Ag2SO4), and cobalt chloride (CoCl2), on the morphogenic and biochemical responses in CAB-6P and Gisela 6 cherry rootstocks were investigated. In both rootstocks, AgNO3 and Ag2SO4 promoted shoot regeneration while CoCl2 had such an effect only in Gisela 6. The rooting percentage of CAB-6P and Gisela 6 explants was diminished with AgNO3, Ag2SO4, and CoCl2. AgNO3 increased root number (40 μM) and root length (50 μM) in the CAB-6P rootstock while it had an inhibitory effect in Gisela 6. Ag2SO4 and CoCl2 enhanced root length …
The Examinations Of Achene Ultrastructural Features Of Section Acrolophus(Centaurea, Asteraceae) Via Scanning Electron Microscopy, Feyza Candan, Tuna Uysal, Osman Tugay, Meryem Bozkurt, Kuddi̇si̇ Ertuğrul, Hakki Demi̇relma
The Examinations Of Achene Ultrastructural Features Of Section Acrolophus(Centaurea, Asteraceae) Via Scanning Electron Microscopy, Feyza Candan, Tuna Uysal, Osman Tugay, Meryem Bozkurt, Kuddi̇si̇ Ertuğrul, Hakki Demi̇relma
Turkish Journal of Botany
In this study, the achene surfaces of 31 taxa belonging to the genus Centaurea L. Were examined in detail by means of electron microscopy. The main aim of this study was to characterize the microsculpture of the achene surface of the Turkish species of Centaurea sect. Acrolophus (Cass.) DC. (Asteraceae). Detailed descriptions of the achene surface were given for each taxon and a fruitful dendrogram was established by numerical analyses derived from the determined micromorphological features. The relationships among the taxa studied were briefly assessed using this generated dendrogram. The results indicated that the examined taxa had very high variations …
Astragalus Topalanense (Fabaceae), A New Species From Turkey, Ahmet İlçi̇m, Lütfi̇ Behçet
Astragalus Topalanense (Fabaceae), A New Species From Turkey, Ahmet İlçi̇m, Lütfi̇ Behçet
Turkish Journal of Botany
Astragalus topalanense Behçet and İlçim sp. Nov. (section Malacothrix Bunge) is described as a new species from Bingöl Province, East Anatolia in Turkey. The new species is similar to Astragalus macrouroides Hub.-Mor., a species endemic to Turkey, and A. Macrourus Fisch. And C.A.Mey. The diagnostic characters and taxonomic comments on the species are presented. Seed and pollen characteristics are investigated using light and scanning electron microscopy. Notes are also presented on its ecology. A distribution map of the new and related species is also provided.
Is There A Difference Between Parkinson Disease Patients And A Control Group In Terms Of Urinary Symptoms And Quality Of Life?, Erdal Benli̇, Fahri̇ye Feri̇ha Özer, Yasemi̇n Kaya, Tuba Şazi̇ye Özcan, Ali̇ Ayyildiz
Is There A Difference Between Parkinson Disease Patients And A Control Group In Terms Of Urinary Symptoms And Quality Of Life?, Erdal Benli̇, Fahri̇ye Feri̇ha Özer, Yasemi̇n Kaya, Tuba Şazi̇ye Özcan, Ali̇ Ayyildiz
Turkish Journal of Medical Sciences
Background/aim: The aim of this study is to research whether urinary symptoms and disruption of quality of life observed in Parkinson disease patients are different than those of their healthy peers. Additionally, whether these complaints were affected by characteristics such as age at onset of Parkinson disease, sex, disease duration, and severity was investigated. Materials and methods: This study comprised a total of 79 individuals, 39 Parkinson patients and a control group of 40 individuals. Parkinson diagnosis was provided by a neurology expert according to the UK Parkinson's Disease Society Brain Bank Criteria. All patients were evaluated by a urologist …
Clinical Characteristics And Outcome Of Brucella Endocarditis, Na Du, Feng Wang
Clinical Characteristics And Outcome Of Brucella Endocarditis, Na Du, Feng Wang
Turkish Journal of Medical Sciences
Background/aim: Brucella endocarditis, which is a rare condition, is the most common cause of death in human brucellosis, leading to severe cardiac complications. By collecting and analyzing clinical cases, we analyzed the clinical characteristics and outcome of Brucella endocarditis in endemic areas in China. Materials and methods: Presented here are 5 cases of Brucella endocarditis, all managed uniformly. We present the clinical, serological, and echocardiographic features; the therapeutic approach; and the follow-up of five patients with Brucella endocarditis. Results: There was a predominance of aortic involvement (4 cases) and a high incidence of left ventricular failure (5 cases). Polymerase chain …
Plasma Levels Of Serotonin, Gastrointestinal Symptoms,And Sleep Problems In Children With Autism, Sorayya Khkheirouri, Parinaz Kalejahi, Seyyed Gholamreza Noorazar
Plasma Levels Of Serotonin, Gastrointestinal Symptoms,And Sleep Problems In Children With Autism, Sorayya Khkheirouri, Parinaz Kalejahi, Seyyed Gholamreza Noorazar
Turkish Journal of Medical Sciences
Background/aim: Autism is a neurodevelopmental disorder identified with higher frequency of serotonin abnormalities and gastrointestinal (GI) and sleep problems. This study aimed to evaluate the plasma levels of serotonin, GI symptoms, and sleep problems, and their relationship with autism severity in children with autism. Materials and methods: Thirty-five children with autism and 31 healthy subjects were studied. GI problems, sleep disorders, and severity of disorder were assessed. Plasma serotonin was determined using ELISA. Results: There was no significant association between GI problems and autism severity, but a significant positive correlation was seen between different indicators of sleep disorder and severity …
The Effect Of Basolateral Amygdala Nucleus Lesion On Memory Under Acute,Mid And Chronic Stress In Male Rats, Hoda Ranjbar, Maryam Radahmadi, Hojjatallah Alaei, Parham Reisi, Sara Karimi
The Effect Of Basolateral Amygdala Nucleus Lesion On Memory Under Acute,Mid And Chronic Stress In Male Rats, Hoda Ranjbar, Maryam Radahmadi, Hojjatallah Alaei, Parham Reisi, Sara Karimi
Turkish Journal of Medical Sciences
Background/aim: The basolateral amygdala (BLA) modulates memory for emotional events and is involved in both stress and memory. This study investigated different durations of stress and the role of BLA on serum corticosterone level and spatial and cognitive memory. Materials and methods: Different durations of stress (acute, mid, and chronic stress), with and without BLA lesion were induced in rats by 6 h/day restraint stress for 1, 7, and 21 days. Memory functions were evaluated by novel object recognition (NOR) and object location test (OLT). Results: The OLT findings showed locomotor activity and spatial memory slightly decreased with different durations …
Chrysin Prevents Brain Damage Caused By Global Cerebralischemia/Reperfusion In A C57bl/J6 Mouse Model, Mehmet Aki̇f Durak, Mustafa Namik Öztanir, Neşe Başak Türkmen, Osman Çi̇ftçi̇, Asli Taşlidere, Mehmet Tecelli̇oğlu, Ari̇f Önder
Chrysin Prevents Brain Damage Caused By Global Cerebralischemia/Reperfusion In A C57bl/J6 Mouse Model, Mehmet Aki̇f Durak, Mustafa Namik Öztanir, Neşe Başak Türkmen, Osman Çi̇ftçi̇, Asli Taşlidere, Mehmet Tecelli̇oğlu, Ari̇f Önder
Turkish Journal of Medical Sciences
Background/aim: The present study investigated the neuroprotective effects of chrysin (CRS) following global cerebral ischemia and reperfusion (I/R) in a C57BL/J6 mouse model. Materials and methods: A total of 40 mice were equally divided into four groups: (1) sham-operated (SH = control), (2) global cerebral I/R (I/R), (3) CRS, and (4) CRS + I/R. In the I/R group, the bilateral carotid arteries were clipped for 15 min and the mice were treated with vehicle (corn oil) for 10 days. In the CRS group, CRS (50 mg/kg) was given for 10 days without carotid occlusion. In the CRS + I/R group …
Effects Of Cepae Extract, Allantoin, And Heparin Mixture On Developing Andalready Formed Epidural Fibrosis In A Rat Laminectomy Model, Rafet Özay, Osman Yüksel Yavuz, Abi̇t Aktaş, Funda Yi̇ği̇t, Nuri̇ Eralp Çeti̇nalp, Haci Mustafa Özdemi̇r, Zeki̇ Şekerci̇
Effects Of Cepae Extract, Allantoin, And Heparin Mixture On Developing Andalready Formed Epidural Fibrosis In A Rat Laminectomy Model, Rafet Özay, Osman Yüksel Yavuz, Abi̇t Aktaş, Funda Yi̇ği̇t, Nuri̇ Eralp Çeti̇nalp, Haci Mustafa Özdemi̇r, Zeki̇ Şekerci̇
Turkish Journal of Medical Sciences
Background/aim: The study was designed to investigate whether local administration of a mixture composed of cepae extract, allantoin, and heparin (CAH) decreased already formed epidural fibrosis (EF) at the laminectomy site. Materials and methods: Twenty-four adult male Sprague Dawley rats were equally divided into four groups. Laminectomy was performed at the L5 level in all rats. The group 2 and group 4 rats were treated with local drug administration. While the group 1 and 2 rats were sacrificed after 6 weeks, the remaining rats were reoperated and CAH mixture was applied in group 4. The vertebral columns of all rats …
Effects Of Naloxone And Yohimbine In Polycystic Ovary Syndrome: A Rabbit Model Study, Sumera Sajjad, Sadia Tobassum, Umer Farooq, Husna Malik, Musadiq Idris
Effects Of Naloxone And Yohimbine In Polycystic Ovary Syndrome: A Rabbit Model Study, Sumera Sajjad, Sadia Tobassum, Umer Farooq, Husna Malik, Musadiq Idris
Turkish Journal of Medical Sciences
Background/aim: To assess the therapeutic effects of naloxone and yohimbine on polycystic ovary syndrome (PCOS) in a rabbit model in terms of body weight and endocrinological parameters (luteinizing hormone, insulin, and estradiol). Materials and methods: A total of 50 adult, reproductively mature female rabbits (Oryctolagus cuniculus) were divided into five groups (n = 10/group). In the control group PCOS was not induced (negative control group), whereas in the remaining four groups (n = 40) PCOS was induced with a single i.m. injection of testosterone daily and were designated as follows: positive control, naloxone-treated (NalT), yohimbine-treated (YohT), and naloxone+yohimbine-treated (NalYT) groups. …
Herbal Self-Medication Use In Type 2 Diabetes Mellitus, Yusuf Aydin, Eli̇f Önder
Herbal Self-Medication Use In Type 2 Diabetes Mellitus, Yusuf Aydin, Eli̇f Önder
Turkish Journal of Medical Sciences
No abstract provided.