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Full-Text Articles in Entire DC Network
Applications Of Crispr/Cas9-Based Genome Editing In The Plant Biology, Yingzhuan Zheng, Qianqian Li, Mingwang Ye, Aie Cehn, Hongyang Wang
Applications Of Crispr/Cas9-Based Genome Editing In The Plant Biology, Yingzhuan Zheng, Qianqian Li, Mingwang Ye, Aie Cehn, Hongyang Wang
Turkish Journal of Botany
Clustered regularly interspaced short palindromic repeats/CRISPR-associated proteins (CRISPR/Cas) is an acquired immune system found in bacteria and archaea that can specifically silence or degrade a foreign single or double strand nucleic acid to protect it from infection. In recent years, the CRISPR/Cas9 system has rapidly been evolved into a genome editing technology, in which the Cas9 endonuclease can be targeted to specific DNA sequences by guide RNAs (gRNAs) that are easily programmable. Due to simplicity, specificity and high efficiency, CRISPR/Cas9 is gradually replacing other gene editing technologies and has been implemented in basic and applied plant sciences to boost yield, …
Traditional Herbal Remedies Used In Kidney Diseases In Turkey: An Overview, Şükran Kültür, Bahar Gürdal, Aynur Sari, Gülay Meli̇koğlu
Traditional Herbal Remedies Used In Kidney Diseases In Turkey: An Overview, Şükran Kültür, Bahar Gürdal, Aynur Sari, Gülay Meli̇koğlu
Turkish Journal of Botany
Ethnobotanical and ethnomedicinal studies have become increasingly recognised as a valuable source of information on the use and possible pharmacological activity of many plant species. There is no study presenting traditional herbal remedies used for kidney diseases in Turkey. The purpose of the paper is to compile herbal remedies used in kidney diseases in Turkey with detailed usage information and chemical constituents. The botanical names, families, and local names; used parts; preparation methods; administration/ dosage; kidney problems and chemical constituents were presented by screening ethnobotanical, ethnomedicinaland phytochemical studies. The most cited plant families, the most cited genera, and the most …
Genetic Structure Of Zannichellia L. Populations According To Mountain Barriers In Iranas Revealed By Issr And Srap Markers, Shabnam Abbasi, Saeed Afsharzadeh, Mehri Dinarvand
Genetic Structure Of Zannichellia L. Populations According To Mountain Barriers In Iranas Revealed By Issr And Srap Markers, Shabnam Abbasi, Saeed Afsharzadeh, Mehri Dinarvand
Turkish Journal of Botany
Zannichellia L. (Potamogetonaceae) is a widespread aquatic genus that is distributed in temperate and subtropical aquatic ecosystems worldwide. Because the biogeographical location of Iran includes mountain ranges and deserts that may cause different habitat types, it was assumed that these Zannichellia populations would be stronger differentiated than observed in Zannichellia from temperate regions. The present study aimed to test whether Z. palustris would demonstrate high levels of genetic differentiation over long distances and across mountain ranges. The genetic structure of the populations of Zannichellia was investigated using inter simple sequence repeats (ISSR) and sequence-related amplified polymorphism (SRAP) as molecular markers. …
Ecological Assessment Of Burç Reservoir's Surface Water (Turkey) Using Phytoplanktonmetrics And Multivariate Approach, Abuzer Çelekli̇, Gülümser Özpinar
Ecological Assessment Of Burç Reservoir's Surface Water (Turkey) Using Phytoplanktonmetrics And Multivariate Approach, Abuzer Çelekli̇, Gülümser Özpinar
Turkish Journal of Botany
The present study aimed to elucidate relationships between phytoplankton species and stressors using multivariate approaches and assess the environmental condition of Burç Reservoir?s surface water using phytoplankton metrics from September 2018 to August 2019 according to implementations of the Water Framework Directive. Burç Reservoir had a characteristic of a warm monomictic pattern. Phytoplankton functional groups (E, F, J, LO, LM, MP , P, S1 , T, and W1 ) were found in the reservoir. A significant difference was found in total biovolume values changed from 2.28 mm3 /L in November 2018 to 0.51 mm3 /L in February 2019. The first …
Development Of A Spiramycin Sensor Based On Adsorptive Stripping Linear Sweepvoltammetry And Its Application For The Determination Of Spiramycin In Chicken Eggsamples, Mustafa Ci̇ttan
Turkish Journal of Chemistry
Herein, an adsorptive stripping linear sweep voltammetric technique was described to determine spiramycin, a macrolide antibiotic, using a carboxylic multiwalled glassy carbon electrode modified with carbon nanotubes. The main principle of the analytical methodology proposed was based on the preconcentration of spiramycin by open-circuit accumulation of the macrolide onto the modified electrode surface. As a result of the adsorption affinity of spiramycin to the modified surface, the sensitivity of the glassy carbon electrode was significantly increased for the determination of spiramycin. The electrochemical behavior of spiramycin was evaluated by cyclic voltammetry and the irreversible anodic peak observed was measured as …
Analyzing Differentially Expressed Genes And Pathways Of Bex2-Deficient Mouse Lung Via Rna-Seq, Noor Bahadar, Hanif Ullah, Salah Adlat, Rajiv Kumar Sah, May Zun Zaw Myint, Zin Mar Oo, Fatoumata Binta Bah, Farooq Hayel Nagi, Hsu Htoo, Ahmad Ud Din, Xuechao Feng, Yaowu Zheng
Analyzing Differentially Expressed Genes And Pathways Of Bex2-Deficient Mouse Lung Via Rna-Seq, Noor Bahadar, Hanif Ullah, Salah Adlat, Rajiv Kumar Sah, May Zun Zaw Myint, Zin Mar Oo, Fatoumata Binta Bah, Farooq Hayel Nagi, Hsu Htoo, Ahmad Ud Din, Xuechao Feng, Yaowu Zheng
Turkish Journal of Biology
Bex2 is well known for its role in the nervous system, and is associated with neurological disorders, but its role in the lung's physiology is still not reported. To elucidate the functional role of Bex2 in the lung, we generated a Bex2 knock-out (KO) mouse model using the CRISPR-Cas9 technology and performed transcriptomic analysis. A total of 652 genes were identified as differentially expressed between Bex2-/- and Bex2+/+ mice, out of which 500 were downregulated, while 152 were upregulated genes. Among these DEGs, Ucp1, Myh6, Coxa7a1, Myl3, Ryr2, RNaset2b, Npy, Enob1, Krt5, Myl2, Hba-a2, and Nrob2 are the most prominent …
Culture Media And Growth Regulators Influence Callus Induction And Plant Regeneration Of Mature Embryos Of Orchardgrass (Dactylis Glomerata L.), Selçuk Kodaz, Kami̇l Hali̇loğlu, Arash Hossein Pour, Murat Aydin
Culture Media And Growth Regulators Influence Callus Induction And Plant Regeneration Of Mature Embryos Of Orchardgrass (Dactylis Glomerata L.), Selçuk Kodaz, Kami̇l Hali̇loğlu, Arash Hossein Pour, Murat Aydin
Turkish Journal of Agriculture and Forestry
To establish an efficient in vitro regeneration protocol for orchardgrass (Dactylis glomerata L.), type of medium, several plant growth regulators and their various concentrations were evaluated in a factorial experiment for callus induction and plant regeneration. Endosperm supported mature embryo were used as explants and optimum response in callus induction was observed on Chu medium with 12 mg/L dicamba (3.6-dichloro-2-methoxybenzoic acid). The highest responding embryogenic callus (15%) was found with Murashige and Skoog medium and 8 mg/L 2.4-D (2,4-dichlorophenoxy acetic acid). The highest regeneration efficiency was achieved on MS medium (17 plantlets) with 8 mg/L 2,4-D. Endosperm-supported mature embryos of …
The Effects Of Increasing Doses Of Nickel And Lead Applications On Some Oriental Tobacco Varieties, Mahmut Tepeci̇k, Mehmet Eşref İrget
The Effects Of Increasing Doses Of Nickel And Lead Applications On Some Oriental Tobacco Varieties, Mahmut Tepeci̇k, Mehmet Eşref İrget
Turkish Journal of Agriculture and Forestry
Heavy metals are hazardous pollutants for humans, animals and plants, when their threshold concentration exceeds. Tobacco can accumulate higher concentrations of heavy metals, and the genotypic differences of tobacco in heavy metal uptake and their growth responses have not been clearly examined. In this study, the effects of nickel (Ni) and lead (Pb) on phytoremediation capabilities were tested in four local Oriental tobacco cultivars (Basma, Akhisar, Sarıbağlar and Dibek). In two pot experiments, nitrogen (N), phosphorus (P) and potassium (P) were applied in fıxed doses, while Pb and Ni were applied at 4 different doses (10, 50, 100 and 150 …
The Current State Of Validated Small Molecules Inhibiting Sars-Cov-2 Non-Structural Proteins, Fati̇h Kocabaş, Merve Uslu
The Current State Of Validated Small Molecules Inhibiting Sars-Cov-2 Non-Structural Proteins, Fati̇h Kocabaş, Merve Uslu
Turkish Journal of Biology
The current COVID-19 outbreak has had a profound influence on public health and daily life. Despite all restrictions and vaccination programs, COVID-19 still can lead to fatality due to a lack of COVID-19-specific treatments. A number of studies have demonstrated the feasibility to develop therapeutics by targeting underlying components of the viral proteome. Here we reviewed recently developed and validated small molecule inhibitors of SARS-CoV-2's nonstructural proteins. We described the validation level of identified compounds specific for SARS-CoV-2 in the presence of in vitro and in vivo supporting data. The mechanisms of pharmacological activity, as well as approaches for developing …
Coronavac (Sinovac) Covid-19 Vaccine-Induced Molecular Changes In Healthy Human Serum By Infrared Spectroscopy Coupled With Chemometrics, Ayça Doğan Mollaoğlu, Rafi̇g Gurbanov, Mete Severcan, Feri̇de Severcan
Coronavac (Sinovac) Covid-19 Vaccine-Induced Molecular Changes In Healthy Human Serum By Infrared Spectroscopy Coupled With Chemometrics, Ayça Doğan Mollaoğlu, Rafi̇g Gurbanov, Mete Severcan, Feri̇de Severcan
Turkish Journal of Biology
From the beginning of the COVID-19 coronavirus pandemic in December of 2019, the disease has infected millions of people worldwide and caused hundreds of thousands of deaths. Since then, several vaccines have been developed. One of those vaccines is inactivated CoronaVac-Sinovac COVID-19 vaccine. In this proof of concept study, we first aimed to determine CoronaVac-induced biomolecular changes in healthy human serum using infrared spectroscopy. Our second aim was to see whether the vaccinated group can be separated or not from the non-vaccinated group by applying chemometric techniques to spectral data. The results revealed that the vaccine administration induced significant changes …
Individual And Combined Effect Of Drought And Heat Stresses In Contrasting Potatocultivars Overexpressing Mir172b-3p, Arslan Asim, Zahi̇de Nesli̇han Öztürk Gökçe, Allah Bakhsh, İlknur Tindaş Çayli, Emre Aksoy, Sevgi̇ Çalişkan, Mehmet Emi̇n Çalişkan, Ufuk Demi̇rel
Individual And Combined Effect Of Drought And Heat Stresses In Contrasting Potatocultivars Overexpressing Mir172b-3p, Arslan Asim, Zahi̇de Nesli̇han Öztürk Gökçe, Allah Bakhsh, İlknur Tindaş Çayli, Emre Aksoy, Sevgi̇ Çalişkan, Mehmet Emi̇n Çalişkan, Ufuk Demi̇rel
Turkish Journal of Agriculture and Forestry
MicroRNAs (miRNAs) are essential players of plant defence systems because of their involvement in reprogramming gene expression under adverse environmental conditions including drought and heat, which are considered major players in limiting crop productivity. miR172b-3p was previously determined as a remarkable stress-responsive miRNA in our next-generation sequencing (NGS) analysis in potato. This study aims to understand the functions of miR172b-3p and its target (ERTF RAP2-7-like) under drought, heat, and combined treatments by overexpressing the miR172b-3p in stress-tolerant (Unica) and sensitive (Russet Burbank) potato cultivars. miR172b-3p overexpression in transgenic lines suppressed the ERTF RAP2-7-like expression leading to enhanced carbon fixation efficiency. …
Evaluation Of Lonicera Caerulea L. Genotypes Based On Morphological Characteristics Offruits Germplasm Collection, Olga Grygorieva, Svitlana Klymenko, Alla Kuklina, Yulia Vinogradova, Olena Vergun, Vladimira Horcinova Sedlackova, Jan Brindza
Evaluation Of Lonicera Caerulea L. Genotypes Based On Morphological Characteristics Offruits Germplasm Collection, Olga Grygorieva, Svitlana Klymenko, Alla Kuklina, Yulia Vinogradova, Olena Vergun, Vladimira Horcinova Sedlackova, Jan Brindza
Turkish Journal of Agriculture and Forestry
It is known that a polymorphic population consisting of a large number of genotypes adapts more rapidly to the environment conditions. The availability of a large gene pool predetermines the success of the introduction and further breeding of new cultivars with economically valuable features. Morphometrics is a classical tool for studying the amplitude of the variability of cultivated plants and evaluating the genotypic diversity of the artificial population. The objective of this study was to evaluate the morphological parameters of Lonicera caerulea L. fruits for 26 genotypes from the population introduced in the M.M. Gryshko National Botanical Garden (Kyiv). Morphological …
Multiplex Fluorescence Quantitative Pcr For The Detection Of Eight Bacterial Pathogens Ofporcine Respiratory Disease Complex (Prdc), Jingbo Wu, Wenjin Nan, Jiangqiang Huang, Guoliang Peng, Honghui Hu
Multiplex Fluorescence Quantitative Pcr For The Detection Of Eight Bacterial Pathogens Ofporcine Respiratory Disease Complex (Prdc), Jingbo Wu, Wenjin Nan, Jiangqiang Huang, Guoliang Peng, Honghui Hu
Turkish Journal of Veterinary & Animal Sciences
As rapid and reliable tools for diagnosis of porcine respiratory disease complex (PRDC) bacterial pathogens are getting more important over time, we established a new multiplex fluorescence quantitative polymerase chain reaction (mFQ-PCR) system with a similar symptom. Our results showed that the system could accurately and simultaneously detect 8 pathogens within 1.5 h. The detection limits were 2-5 standard DNA copies. The correlation coefficient of the standard curve was more than 0.998, with a well dynamic range from 101 to 109, and the intra- and intervariation coefficients (CVs) were less than 2.06%. After setting the positive threshold of Ct value, …
Chemical Castration Using An Intratesticular Injection Of Mannitol: A Preliminary Studyin A Rat Model, Mohammad-Ali Maadi, Mehdi Behfar, Amir Rasaei, Ali Shalizar-Jalali, Gholamreza Najafi, Vahid Mohammadi
Chemical Castration Using An Intratesticular Injection Of Mannitol: A Preliminary Studyin A Rat Model, Mohammad-Ali Maadi, Mehdi Behfar, Amir Rasaei, Ali Shalizar-Jalali, Gholamreza Najafi, Vahid Mohammadi
Turkish Journal of Veterinary & Animal Sciences
This study was aimed to evaluated chemical sterilization using an intra-testicular injection of mannitol 20% in rats. Fifty male Wistar rats were divided into five groups, including 1) intact, 2) surgical castration and, 3 to 5) intra-testicular injections of normal saline, hypertonic saline, and mannitol, respectively. The baseline testosterone levels were measured. Surgical castration was performed in group 2. Intra-testicular injections were performed in groups 3, 4, and 5. On day 60, the testosterone level was evaluated. Then, sperm count, viability, motility, morphological abnormalities and DNA damage were studied. Gonadosomatic index was recorded on day 60. Serum testosterone level was …
Comparison Of Feed Value Of Amaranthus Powellii Willd. Forage To Some Roughagefeeds, Gökhan Fi̇li̇k, Ayşe Gül Fi̇li̇k
Comparison Of Feed Value Of Amaranthus Powellii Willd. Forage To Some Roughagefeeds, Gökhan Fi̇li̇k, Ayşe Gül Fi̇li̇k
Turkish Journal of Veterinary & Animal Sciences
The aim of this study was to compare the chemical composition, in vitro digestibility, protein and energy value, roughage value of Amaranthus powellii Willd. forage to the most commonly used alfalfa hay and wheat straw in ruminant nutrition. Amaranthus powellii Willd. forage has the potential to be a third quality roughage according to its relative feed value assessment of 104.55 ± 0.67. In addition, the relative forage quality assessment developed for feeding dairy cattle was 97.73 ± 0.05 for Amaranthus powellii Willd. forage, which had a higher the relative forage quality value than alfalfa hay and wheat straw, and it …
Residue Depletion Of Sarafloxacin In Black-Bone Silky Fowl Tissues After Oraladministration, Bao-Tao Liu, Shi-Kai Sun, Li Chen, Junjun Yu
Residue Depletion Of Sarafloxacin In Black-Bone Silky Fowl Tissues After Oraladministration, Bao-Tao Liu, Shi-Kai Sun, Li Chen, Junjun Yu
Turkish Journal of Veterinary & Animal Sciences
In this study, the residue depletion of sarafloxacin in black-bone silky fowl (BSF) was studied after oral doses of sarafloxacin (10 mg/kg BW for 7 consecutive days). Muscle and liver tissues were collected at differentwithdrawal periods and determined by HPLC-MS/ MS method. The limit of detection for sarafloxacin was 1.0 μg/kg, and the recoveries from blank fortified samples were 93.53%~108.47% with coefficients of variation less than 9.28%. At first day after ending sarafloxacin treatment, the mean concentrations of sarafloxacin in muscle and liver were 366.88 ± 129.51 and 120.35 ± 46.86 μg/kg, respectively, higher than their maximum residue limits (10 …
Effect Of Vanadium (Iv) Chloride Supplementation On Appetite-Related Hormone Levels Inrats With Experimentally Induced Diabetes, Tünay Kontaş Aşkar, Adnan Adi̇l Hi̇şmi̇oğullari, Olga Büyükleblebi̇ci̇, Hati̇ce Nur Er Sarikaya
Effect Of Vanadium (Iv) Chloride Supplementation On Appetite-Related Hormone Levels Inrats With Experimentally Induced Diabetes, Tünay Kontaş Aşkar, Adnan Adi̇l Hi̇şmi̇oğullari, Olga Büyükleblebi̇ci̇, Hati̇ce Nur Er Sarikaya
Turkish Journal of Veterinary & Animal Sciences
Vanadium is one of the essential trace elements for mammals, which has important functions in the metabolism of carbohydrates. There is limited data about the effects of vanadium (IV) chloride supplementation on appetite-related hormones in literature. Our target was to analyse the impacts of vanadium supplementation on appetite-related hormone (leptin, nesfatin-1 and apelin) levels in rats with experimentally induced diabetes. Twenty eight male Sprague-Dawley albino rats were used in this study. After formation of diabetes, 0.3 mg/mL of vanadium was added to drinking water of rats for four weeks. A substantial increment was found in serum glucose (p < 0.001), HbA1c (p < 0.001), HOMA-IR (p < 0.01), and leptin (p < 0.001) levels and a significant decrease in insulin, apelin and nesfatin-1 concentrations in diabetic rats. Moreover, blood glucose, HbA1c, HOMA-IR, and leptin levels decreased in diabetic + vanadium group, but nesfatin-1 (1.74 ± 0.94 ng/mL), apelin (1.74 ± 0.94 ng/mL), and insulin concentrations were found higher compared with the diabetic group. As a result of this study, vanadium has increased the levels of circulating nesfatin-1 and apelin levels in diabetic rats while decreasing blood glucose and leptin concentrations. But further studies are required to determine the blood glucose lowering effects of vanadium and its relationship with appetite related hormones in diabet.
Detection Of Varroa Mites From Honey Bee Hives By Smart Technology Var-Gor: A Hivemonitoring And Image Processing Device, Sedat Sevi̇n, Hi̇dayet Tutun, Seli̇me Mutlu
Detection Of Varroa Mites From Honey Bee Hives By Smart Technology Var-Gor: A Hivemonitoring And Image Processing Device, Sedat Sevi̇n, Hi̇dayet Tutun, Seli̇me Mutlu
Turkish Journal of Veterinary & Animal Sciences
The major honey bee parasite Varroa destructor reduces hive vitality and honey yields by preventing growth of heathy bees and causes drastic loss in apiculture. Therefore, mite infestation in honey bee needs to be constantly controlled by beekeepers. To minimize this loss, a system called Var-Gor has been developed with the aim of controlling Varroa mite infestation before/just after entering the hive instead of the late period. Var-Gor is a hive entrance attachable device box consist of bee passage tunnels (width: 25 mm, height: 15 mm, and depth: 50 mm), autofocus detection camera combined with interface (process sensor: IV-HG10) and …
Indigenous Entomopathogenic Fungi As Potential Biological Control Agents Of Rose Sawfly, Arge Rosae L. (Hymenoptera: Argidae), Derya Baki̇, Hi̇lal Şule Tosun, Fedai̇ Erler
Indigenous Entomopathogenic Fungi As Potential Biological Control Agents Of Rose Sawfly, Arge Rosae L. (Hymenoptera: Argidae), Derya Baki̇, Hi̇lal Şule Tosun, Fedai̇ Erler
Turkish Journal of Zoology
The rose sawfly, Arge rosae L. (Hymenoptera: Argidae), is one of the most destructive pests of roses grown both indoors and outdoors in Antalya province (south-western part of Turkey). Especially in greenhouse rose cultivation, growers depend heavily on synthetic pesticides to control this pest along with other arthropod pests in their crops. The aim of this study was to evaluate biocontrol potential of some indigenous soil-borne entomopathogenic fungi (EPF) against the pest. In pathogenicity assays, a total of 17 EPF isolates, belonging to three species [Beauveria bassiana (Bals.) Vuill. - 14, Clonostachys rosea (Link) Schroers - 2 and Isaria farinosa …
Infestation And Effect Of Parasitic Isopod Epipenaeon Ingens Ingens Nobili, 1906 Oncommercial Shrimp Species In The Eastern Mediterranean: A Case Study Of The Populationof Brown Shrimp Penaeus Aztecus Ives, 1891, Mehmet Cengi̇z Deval, Fatma Gonca Koçanci
Infestation And Effect Of Parasitic Isopod Epipenaeon Ingens Ingens Nobili, 1906 Oncommercial Shrimp Species In The Eastern Mediterranean: A Case Study Of The Populationof Brown Shrimp Penaeus Aztecus Ives, 1891, Mehmet Cengi̇z Deval, Fatma Gonca Koçanci
Turkish Journal of Zoology
Monthly samples of seven species of penaeid shrimps, namely, Penaeus aztecus (Ives, 1891), Penaus hathor (Burkenroad, 1959) Penaus japonicus (Spence Bate,1888), Penaus kerathurus (Forskal,1775), Penaus semisulcatus (De Haan,1844), Metapenaeus monoceros (Fabricus, 1798) and Metapenaeopsis aegyptia (Galil & Golani, 1990) were collected from Antalya Bay in the Eastern Mediterranean Sea from March, 2019 through March, 2020. Except for P. aztecus and P. semisulcatus, no other shrimp species were infected with the parasitic isopod Epipenaeon ingens ingens. Of the 3043 P. aztecus shrimp inspected, 541 individuals were infected (17.8%) with the bopyrid parasite E. ingens ingens. However, the annual infestation rate in …
Identification Of Micrornas In The Follicular And Luteal Tissues Of Holstein-Friesian Cows, Selçuk Özdemi̇r, Seli̇m Çomakli
Identification Of Micrornas In The Follicular And Luteal Tissues Of Holstein-Friesian Cows, Selçuk Özdemi̇r, Seli̇m Çomakli
Turkish Journal of Veterinary & Animal Sciences
MicroRNAs (miRNAs) regulate many physiological pathways, including development, cell differentiation, immune response as well as diseases by post-transcriptional processes. However, information is limited regarding the biological roles of miRNAs in the development of the follicular and luteal tissues in cows. The main aim of the present study was to identify miRNAs that are expressed in the follicular and luteal tissues of cows. We used a comparative RNA sequencing method to identify miRNA candidates that might play key roles in the follicular and luteal phases of Holstein cows. Nine miRNAs were expressed at a high ratio: 8 in the follicular tissue …
The Ichthyofaunal Diversity Of Freshwater Ecosystems In Gökçeada Island (Nw Turkey)Under The Pressure Of Nonnative Species, Sevan Ağdamar, Gülşah Saç, Özcan Gaygusuz, Ersi̇n Doğaç, Ümi̇t Acar, Çi̇ğdem Gürsoy Gaygusuz, Müfi̇t Özuluğ
The Ichthyofaunal Diversity Of Freshwater Ecosystems In Gökçeada Island (Nw Turkey)Under The Pressure Of Nonnative Species, Sevan Ağdamar, Gülşah Saç, Özcan Gaygusuz, Ersi̇n Doğaç, Ümi̇t Acar, Çi̇ğdem Gürsoy Gaygusuz, Müfi̇t Özuluğ
Turkish Journal of Zoology
Freshwater ecosystems have a greater value for biodiversity per surface area than terrestrial and marine ecosystems. Streams and lakes are notably prone to biodiversity loss, being the greatest threats habitat destructions and nonnative species. The aim of the present study is to assess the fish composition of lotic and lentic water systems of an island ecosystem (Gökçeada Island, Turkey), which is poorly studied, and to highlight the entry routes and possible impacts of translocated fish species in an island ecosystem. The field surveys were conducted in a total of 14 sampling sites (five reservoirs and nine streams) in the inland …
Integrating Indicators Of Natural Regeneration, Enrichment Planting, Above-Ground Carbonstock, Micro-Climate And Soil To Asses Vegetation Succession In Postmining Reclamation Intropical Forest, Trimanto Trimanto, Lia Hapsari, Sugeng Budiharta
Integrating Indicators Of Natural Regeneration, Enrichment Planting, Above-Ground Carbonstock, Micro-Climate And Soil To Asses Vegetation Succession In Postmining Reclamation Intropical Forest, Trimanto Trimanto, Lia Hapsari, Sugeng Budiharta
Turkish Journal of Botany
Open-cast mining in tropical forests causes negative impacts on biodiversity and carbon storage. Postmining reclamation is therefore imposed to recover the vegetation despite the lack of understanding which indicators can be used to monitor the progress ofsuccession. This study proposes an integrated framework to assess the trajectory of vegetation succession in coal mining site in East Kalimantan, Borneo. We combine the indicators of floristic diversity of naturally growing terrestrial and epiphytic plants, survival and growth of enrichment planting of native plants, above-ground carbon stock of pioneer trees, and the measurements on micro-climate and soil conditions. We compare some indicators across …
Gc-Ms Profiling, Antioxidant, Antimicrobial Activities, Dna Cleavage Effect Ofsymphytum Aintabicum Hub.-Mor. & Wickens (Boraginaceae) And Its Anticancer Activityon Mcf-7 Cell Line, Alevcan Kaplan
Turkish Journal of Botany
Symphytum species, generally known as comfrey, have been used for ancient times in folk medicine for wounds, bone breakages, rheumatism, liver problems, and innumerable potentialities. However, many of the species belonging to the genus Symphytum have not been analyzed with scientific methods and principles yet. Therefore, this work is a guide for determining and researching the main gaps in the literature. In this study, MeOH and petroleum ether (PE) extracts of Symphytum aintabicum Hub.-Mor. & Wickens were analyzed for their biological activities and GC-MS analysis, antioxidant, antimicrobial activities, DNA cleavage effect, and anticancer activity on the MCF-7 human breast cell …
Screening Of Cytotoxicity And Dna Topoisomerase Iia Inhibitory Activity Of Turkish Onosma Species, Özge Güzel, Seda Duman, Si̇nem Yilmaz, Çi̇ğdem Karakoyun, Demet Kul, Ademi̇ Fahri̇ Pi̇rhan, Erdal Bedi̇r
Screening Of Cytotoxicity And Dna Topoisomerase Iia Inhibitory Activity Of Turkish Onosma Species, Özge Güzel, Seda Duman, Si̇nem Yilmaz, Çi̇ğdem Karakoyun, Demet Kul, Ademi̇ Fahri̇ Pi̇rhan, Erdal Bedi̇r
Turkish Journal of Botany
Onosma L., the largest genus of Boraginaceae, is represented by 105 species in Turkey with an endemism rate of 52%. Phytochemical studies indicate that Boraginaceae plants mainly comprise naphthoquinones with a wide range of biological activities including anticancer, antiinflammatory, wound healing, and antioxidant effects. However, few taxa of the genus Onosma have been investigated in detail for their bioactivities. Considering the high rate of endemism and an inadequate number of bioactivity screening studies in literature, we aimed to evaluate the cytotoxic effects and topoisomerase inhibitory activities of some Onosma species growing in southwestern Turkey. Here, we describe a comprehensive cytotoxic …
Anticancer, And Antioxidant Activities Of Royal Jelly On Ht-29 Colon Cancer Cells Andmelissopalynological Analysis, Adnan Ayna, Abdullah Tunç, Seda Nur Özbolat, Aydin Şükrü Bengü, Gürkan Aykutoğlu, Deni̇z Canli, Ridvan Polat, Mehmet Çi̇ftci̇, Ekrem Darendeli̇oğlu
Anticancer, And Antioxidant Activities Of Royal Jelly On Ht-29 Colon Cancer Cells Andmelissopalynological Analysis, Adnan Ayna, Abdullah Tunç, Seda Nur Özbolat, Aydin Şükrü Bengü, Gürkan Aykutoğlu, Deni̇z Canli, Ridvan Polat, Mehmet Çi̇ftci̇, Ekrem Darendeli̇oğlu
Turkish Journal of Botany
Royal jelly (RJ) is reflecting the flora around the apiaries as a result of the foraging activity of honeybees and therefore, pollen analysis could be used to verify its botanical/geographical origin. Colon cancer treatment by means of chemotherapeutics agents reflects a substantial problem for the organism due to high toxicity to other viable cells of the body. To explore a chemopreventive approach to enhancing colon cancer treatment efficacy, the antioxidant and antiproliferative effects of RJ in HT-29 colon cancer cells were assessed. Cell proliferation was performed by WST-1 assay, index of apoptosis was calculated by TUNEL Assay, antioxidant activities were …
Treatment Of Sars-Cov-2 Pneumonia With Favipiravir: Early Results From The Egeuniversity Cohort, Turkey, Hüseyi̇n Aytaç Erdem, Pervi̇n Korkmaz Ekren, Derya Çağlayan, Meltem Taşbakan, Tansu Yamazhan, Mehmet Sezai̇ Taşbakan, Abdullah Sayiner, Ayşe Deni̇z Gökengi̇n
Treatment Of Sars-Cov-2 Pneumonia With Favipiravir: Early Results From The Egeuniversity Cohort, Turkey, Hüseyi̇n Aytaç Erdem, Pervi̇n Korkmaz Ekren, Derya Çağlayan, Meltem Taşbakan, Tansu Yamazhan, Mehmet Sezai̇ Taşbakan, Abdullah Sayiner, Ayşe Deni̇z Gökengi̇n
Turkish Journal of Medical Sciences
Background/aim: The aim of this descriptive article is to share the experience in Ege University, Turkey with favipiravir in the treatment of severe SARS-CoV-2 pneumonia. Materials and methods: This retrospective descriptive study included patients diagnosed with COVID-19 who presented with or developed severe pneumonia. Results: Forty patients who completed a full course (at least 5 days) of favipiravir were included in the study. At baseline, 30 (75%) patients required treatment for respiratory distress. Thirty-three patients (82.5%) were discharged from the hospital with full recovery, 6 patients (15%) died and 1 case (2.5%) was still at the intensive care unit (ICU) …
Clinical And Molecular Findings In 37 Turkish Patients With Isolated Methylmalonic Acidemia, Berna Şeker Yilmaz, Deni̇z Kör, Fatma Derya Bulut, Sebi̇le Kilavuz, Serdar Ceylaner, Hali̇se Nesli̇han Önenli̇ Mungan
Clinical And Molecular Findings In 37 Turkish Patients With Isolated Methylmalonic Acidemia, Berna Şeker Yilmaz, Deni̇z Kör, Fatma Derya Bulut, Sebi̇le Kilavuz, Serdar Ceylaner, Hali̇se Nesli̇han Önenli̇ Mungan
Turkish Journal of Medical Sciences
Background/aim: Isolated methylmalonic acidemia (MMA) is caused by complete or partial deficiency of the enzyme methylmalonylCoA mutase (mut0 or mut- enzymatic subtype), a defect of its cofactor adenosyl-cobalamin (cblA, cblB, or cblD-MMA), or deficiency of the enzyme methylmalonyl-CoA epimerase. While onset of the disease ranges from the neonatal period to adulthood, most cases present with lethargy, vomiting and ketoacidosis in the early infancy. Major secondary complications are; growth failure, developmental delay, interstitial nephritis with progressive renal failure, basal ganglia injury and cardiomyopathy. We aimed to demonstrate clinical and molecular findings based on long-term follow up in our patient cohort. Materials …
The Effects Of Water Immersion And Epidural Analgesia On Cellular Immune Response,Neuroendocrine, And Oxidative Markers, Özlem Uzunlar, Ümi̇t Yasemi̇n Sert Di̇nç, Nezaket Kadioğlu, Tuba Çandar, Yaprak Üstün
The Effects Of Water Immersion And Epidural Analgesia On Cellular Immune Response,Neuroendocrine, And Oxidative Markers, Özlem Uzunlar, Ümi̇t Yasemi̇n Sert Di̇nç, Nezaket Kadioğlu, Tuba Çandar, Yaprak Üstün
Turkish Journal of Medical Sciences
Background/aim: Water immersion and epidural analgesia are the most preferred pain relief methods during the labor process. Adverse effects related to these methods, impact on the labor, and perception of pain is well studied in the literature. We aimed to investigate the cord blood level of copeptin, total serum oxidant (TOS), antioxidant (TAS), interleukin (IL)-1, IL-6, and oxytocin after the labor with water immersion, epidural analgesia, and vaginal birth without pain relief. Materials and methods: The study was conducted with 102 healthy pregnant women admitted to the obstetric delivery unit for noncomplicated term birth. Copeptin, oxytocin, TAS, TOS, IL-1, and …