Digital Commons Network^™

Dynamics Of Vibrio With Virulence Genes Detected In Pacific Harbor Seals (Phoca Vitulina Richardii) Off California: Implications For Marine Mammal Health, Stephanie Nichole Hughes

Master's Theses

Given their coastal site fidelity and opportunistic foraging behavior, harbor seals (Phoca vitulina) may serve as sentinels for coastal ecosystem health. Seals using urbanized coastal habitat can acquire enteric bacteria, including Vibrio, that may affect their health. To understand Vibrio dynamics in seals, demographic and environmental factors were tested for predicting potentially virulent Vibrio in free-ranging and stranded Pacific harbor seals (P. v. richardii) off the coast of California. Vibrio prevalence did not vary with season and was greater in free-ranging seals (29%, n = 319) compared with stranded seals (17%, n = 189). Of …

Utilization Of Protein Tertiary Contacts To Improve Protein Structure Prediction Using Sequence Homology, Trung Thanh Nguyen

Master's Theses

The structure of a protein ultimately determines its function; therefore, knowledge of three-dimensional structure is essential for understanding its function and mechanism of action. The two most common methods for determining protein structure are x-ray crystallography and Nuclear Magnetic Resonance (NMR) spectroscopy. These methods are quite successful but can be very time-intensive and costly. An alternative method is protein structure prediction, where structure is computationally predicted from amino acid sequence. As opposed to x-ray crystallography and NMR spectroscopy, protein structure prediction is not encumbered by potential experimental problems. In this research, we attempted to determine if certain protein structure features, …

Determining The Intracellular Concentrations Of Flavonoids In Mda-Mb-231 Cells Using Hplc-Coupled Mass Spectrometry, Anh Dang Pham

Master's Theses

Flavonoids are polyphenolic compounds found in a wide variety of plants. In recent years, flavonoids have been found to be beneficial to human health. Our lab has investigated the ability of flavonoids to induce cytotoxicity in human breast cancer cell lines. We have discovered that some compounds can induce cytotoxicity very readily, whereas others cannot. We hypothesized that this difference is attributable to a compound's ability to transverse the cell membrane. Therefore, we used LC-MS to measure the amount of each flavonoid that is able to enter into MDA-MB-231 cells, human breast cancer cells. We tested 14 flavonoids. MDA-MB-231 cells …

Profiling Flavonoid Cytotoxicity In Human Breast Cancer Cell Lines, Sina Yadegarynia

Master's Theses

Flavonoids are part of a large family of polyphenols that are found extensively in fruits and vegetables. This class of compounds has been of considerable medical interest due to their anti-inflammatory and anti-cancer activities. Although extensive effort has been made to identify the biological effects responsible for the chemopreventive activity of these compounds, the exact molecular mechanisms involved are not fully understood. In this study, we focused on the cytotoxic effects of fourteen different flavonoids against a series of breast cancer cell lines and evaluated the induction of cell cycle arrest at G1 or G2/M phase as result of such …

A Descriptive Study Of Old-Growth Sequoia Sempervirens Growth Form And Canopy Structure On A Pygmy Forest Ecotone In Mendocino County, Zuhayl Rochin Lambert

Master's Theses

The tallest tree in the world is the coast redwood, Sequoia sempervirens, a species endemic to a 16-km-wide coastal belt extending from Big Sur, California, to southern Oregon. Old-growth redwood forests are home to other plant and animal species that depend on structural characteristics that have formed over hundreds of years. While a great deal of research regarding growth form and structure has taken place on highly productive stands, little work has been done on marginal sites, where redwoods are on the edge of their ecological tolerance. In the Northern California County of Mendocino, hydrophobic spodosol are host to …

The Effects Of Restored Aquatic Large Woody Debris Structures On Invertebrate Populations In The Napa River, Clayton Christopher Leal

Master's Theses

Agricultural encroachment and habitat destruction within the riparian zone of many California ecosystems have created a need for restoration of stream hydrology in order to enhance and support native flora and fauna. On the Napa River, adjacent vineyards have caused the channel to become deeply incised, so that the stream now lacks geomorphic variability and biodiversity. In order to restore channel complexity, large woody debris (LWD) structures were installed in the river in the summer of 2010. In this study I evaluated the effects of installing LWD structures within the Napa River on benthic invertebrates in the first year after …

Investigation Of The Role Of Dietary Flavonoids On Cell Death: Evidence To Support A Non-Classical Apoptotic Mechanism, Tetiana Lialiutska

Master's Theses

Flavonoids are polyphenolic compounds widely distributed in plants and have been shown to be cytotoxic to cancer cells. Our lab has previously shown that some flavonoids are able to induce cytotoxicity and inhibit caspase activity in human breast cancer cell lines. The goal of our study was to identify the specific molecular pathways required for flavonoid-induced cytotoxicity. MDA-MB-231 cells, mouse embryonic fibroblasts (MEFs) lacking caspase 3 and 7, and primary baby mouse kidney epithelial cells lacking Bax and Bak were cultured. Flavonoid-treated MDA-MB-231 cells showed cytochrome c release. We detected caspase 3 activation and PARP cleavage in MDA-MB-231 cells after …

Ethics And Wolf Management: Attitudes Toward And Tolerance Of Wolves In Washington State, Julie Callahan

Master's Theses

Approximately seventy-five years after extirpation from Washington State, gray wolves (Canis lupus) returned. As of December 2012, eight packs had arrived from adjacent states and provinces. Delisted from the Federal Endangered Species List in the eastern one-third of Washington, state wildlife managers now have the authority to manage wolves without federal supervision. As a result, one seven-wolf pack has been destroyed. The current study was developed to provide information for managers and policymakers to modify wolf management policies to fit the new regulatory context. Effects of a range of cultural and demographic factors on attitudes toward wolves and tolerance of …

A Study On Taiwanese International Students And Taiwanese American Students: The Interface Between Naming And Identity, Yi-An Chen

Master's Theses

In this study, I analyze how Chinese and English naming practices influence name adoption and explicate how the use and choice of names by Taiwanese international students and Taiwanese American students at San José State University, California, are structured through social interaction and cultural context. The data were collected from in-depth interviews with 10 Taiwanese international students and 10 Taiwanese American students. The interviews focused on how they construct their identities and produce social relations with others through their choice and use of ethnic and/or English names.

The study findings help to illuminate areas that until now have not received …

Comparing Journal Impact Factor And H-Type Indices In Virology Journals, Zao Liu, Gary (Gang) Wan

Library Philosophy and Practice (e-journal)

This paper examines the relationships between the journal impact factor and the h-type indices in virology journals. The virology journals and their 2010 journal impact factors were retrieved from Journal Citation Reports. The h-index and the g-index values of the journals for 2007-2011 were obtained from Web of Science and Google Scholar. The journals were ranked by their journal impact factor and h-indices. The correlation analysis of the measures found a strong relationship between the journal impact factor and the h-type indices, and a stronger tie between the h-indices themselves. Despite the strong correlations between the measures, differences in rankings …

Use Of E-Resources By Life Scientists: A Case Study Of Sambalpur University, India, Bipin Bihari Sethi, K. C. Panda

Library Philosophy and Practice (e-journal)

E-resources in collaboration with Internet have become a sign of modern age being an invaluable tool for teaching, learning, and research. The library and information landscape has transformed with the onset of the digital era and today traditional libraries have changed their roles to serve as ‘Knowledge Centers’ with priority on value added electronic information services. Academic and research institutions are focusing on how best they can facilitate research by canalizing specific information services which compliment as cutting-edge technology. With the advent of globalization in the realm of education, there has been an information explosion. Most of the science and …

Direct Manipulation Tablet Apps For Education: How Should We Understand Them?, Rich Burkhard, Timothy Hill, Shailaja Venkatsubramanyan, Chang Kim

Faculty Research, Scholarly, and Creative Activity

As the iPad and its competitors create a new product category – apps for mobile, multimedia tablets with touch and gesture interfaces – many are convinced that tablet apps will revolutionize education. For example, hand-controlled, direct manipulation features offer new ways to convey both spatial and abstract concepts, and progressive storylines can adapt to users in real-time. While the effectiveness of tablet apps for learning may seem obvious to new users, how and why particular apps might be effective is new research territory, and the relevance of existing learning theory is unknown. We describe a research program that will explore …

Spartan Daily December 8, 2011, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 137, Issue 53

Global Change, Global Trade, And The Next Wave Of Plant Invasions, Bethany A. Bradley, Dana M. Blumenthal, Regan Early, Edwin D. Grosholz, Joshua J. Lawler, Luke P. Miller, Cascade J.B. Sorte, Carla M. D'Antonio, Jeffrey M. Diez, Jeffrey S. Dukes, Ines Ibanez, Julian D. Olden

Faculty Publications, Biological Sciences

Many non-native plants in the US have become problematic invaders of native and managed ecosystems, but a new generation of invasive species may be at our doorstep. Here, we review trends in the horticultural trade and invasion patterns of previously introduced species and show that novel species introductions from emerging horticultural trade partners are likely to rapidly increase invasion risk. At the same time, climate change and water restrictions are increasing demand for new types of species adapted to warm and dry environments. This confluence of forces could expose the US to a range of new invasive species, including many …

Spartan Daily December 1, 2011, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 137, Issue 49

Spartan Daily November 29, 2011, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 137, Issue 47

Spartan Daily November 22, 2011, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 137, Issue 46

Spartan Daily November 16, 2011, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 137, Issue 43

Spartan Daily November 10, 2011, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 137, Issue 41

Spartan Daily November 3, 2011, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 137, Issue 37

Status Of Institutional Repositories In Asian Countries: A Quantitative Study, Mohammad Nazim, Bhaskar Mukherjee

Library Philosophy and Practice (e-journal)

With the development of information communication technologies, a number of alternative strategies to the traditional scholarly publishing system have been evolved. Among these, Open Access (OA) model which promise to be extremely advantageous to peers everywhere, especially to those who have acute shortage of resources for purchasing scholarly literature. The impetus of OA was boosted by the Open Society Institute (OSI) in a small meeting convened in Budapest on December 1-2, 2001. The purpose of the meeting was to accelerate progress in the international effort to make research literature in all academic fields freely available on the Internet (OAIS, 2002; …

An Exploratory Study Of Indian Science And Technology Publication Output, G. Buchandiran

Library Philosophy and Practice (e-journal)

The contribution of a nation to research promotes the knowledge building process. Understanding the research contribution of a nation is the basic component in science policy. In reality, science auditing is a complex process. The science policy makers employ a large number of science indicators - not all are equally important. Metrics employed in this study are not comprehensive as they are limited to scientific publications. Science auditing is not confined to a small set of indicators. To arrive at a broad science policy, we need to use many other indicators.

The paper presents the data and analyses and the …

University Scholar Series: Brandon White, Brandon White

University Scholar Series

Use and Applications of HeLa Cells in Science and Biotechnology

On October 26, 2011, Dr. Brandon White spoke in the University Scholar Series hosted by Provost Gerry Selter at the Dr. Martin Luther King, Jr. Library. Brandon White is an Assistant Professor in Biological Sciences at SJSU, teaching courses in molecular biology, molecular biological techniques, and cell biology. His research focuses on Notch signaling and identification, and characterization of natural products involved in cell death of cancer cells. In this seminar, Dr. Brandon White discusses the use and applications of HeLa cells in science and biotechnology.

Spartan Daily October 25, 2011, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 137, Issue 31

Spartan Daily October 24, 2011, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 137, Issue 30

Hybrid Veggies & Mixed Kids: Ecocriticism And Race In Ruth Ozeki's Pastoral Heartlands, Melissa Eriko Poulsen

Asian American Literature: Discourses & Pedagogies

This paper explores the troping of racial categories and mixed race bodies in Ruth Ozeki’s All Over Creation (2003) and My Year of Meats (1999). Moving through both transnational and local space, Ozeki’s writes an ecocritical pastoral text in order to resist representations of people of mixed race stemming from nineteenth century racial theory. Drawing attention to the consumption of food within and across national borders, whether genetically modified potatoes or hormone-infused beef, Ozeki simultaneously highlights the uncritical consumption of the language of biology around the mixed race body. All Over Creation and My Year of Meats are constructed around …

A Psychoanalytical Approach To Bich Minh Nguyen's Stealing Buddha's Dinner, Wenying Xu

Asian American Literature: Discourses & Pedagogies

Racial minorities in the U.S. are often tormented by the tension between the corporeal and the ontological, with the former experienced as confining and the latter expansive. Such ambivalence often expresses itself in one's relationship with food. Here I propose to illustrate how Jacques Lacan's psychoanalytical theory on desire can assist us in understanding ethnicity as a bodily performance, which I venture to call an embodied ontology, applying this concept to Bich Minh Nguyen's Stealing Buddha's Dinner (2007).

Spartan Daily October 17, 2011, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 137, Issue 27

Spartan Daily October 10, 2011, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 137, Issue 23

Spartan Daily October 6, 2011, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 137, Issue 22