Digital Commons Network^™

Defining Replication-Coupled Chromatin Assembly Pathways And Their Effect On Silencing And Responses To Dna Damage In Saccharomyces Cerevisiae, Tiffany J. Young

Open Access Dissertations

The genetic information of a cell is organized in a DNA and protein structure referred to as chromatin. Chromatin consists of repeating units called nucleosomes, which consists of 147 base pairs of DNA wrapped around an octamer of histone proteins. These histone proteins are post-translationally modified at specific residues that are important gene regulation and genomic stability. Altered histone modification patterns are strongly associated with multiple cancers, underlying the importance of better understanding the pathways that regulate these modifications. During DNA replication, chromatin must be disassembled, and then reassembled behind the replication fork. Defects in this process can cause alterations …

Designing Hand-Driven Input With Novel Sensing Techniques For Natural Interactions In Tangible And Soft Interfaces, Sang Ho Yoon

Open Access Dissertations

The advancements in electrical components and computing power have introduced new types of sensing capabilities and interfaces. To support upcoming interfaces like augmented/virtual reality (AR/VR), previous studies suggested on utilizing natural correspondences like human motions and natural behaviors [1]. However, conventional input methods still rely on utilizing built-in motion and touch sensors. Although these approaches are offered in effective and efficient manner, they do not fully accommodate human’s natural motions and behaviors as a meaningful input metaphor. Introducing new sensing techniques that are capable of understanding human motions and behaviors will become essential in supporting emerging interfaces. Recent works have …

The Regulation Of Calcium Oscillations In Porcine Eggs At Fertilization, Lu Zhang

Open Access Dissertations

As the most abundant mineral in organisms, ionized calcium (Ca2+) plays a crucial role in cellular signaling, regulating a great number of physiological activities. In this study, the Ca2+ entry mechanism that sustains the long-lasting Ca2+ oscillations in fertilized pig eggs was investigated. Porcine eggs matured in vitro were used for the experiments. In some eggs, the intracellular Ca2+ stores were depleted using cyclopiazonic acid (CPA, a SERCA pump blocker), others were inseminated with boar spermatozoa. To identify the mechanism that mediates the Ca2+ influx, various inhibitors of store-operated Ca2+ entry (SOCE) were used. We found that the inhibitors blocked …

Formative Research On An Instructional Design Theory For Fostering Self-Efficacy Through Gamification, Stacey Zurek

Open Access Dissertations

The merits of gamification as a learner-centered pedagogy that positively influences learner engagement and motivation are widely established in the literature; yet, few studies have ventured beyond motivation to consider the impact gamification has on self-efficacy. Moreover, guidance for the effective design and development of gamified instruction is lacking. This study describes formative research conducted on the Gamification for Enhancing Learner Self-Efficacy (GELSE) instructional design theory, which was developed to guide the design of gamification aimed at fostering self-efficacy. The goal of formative research is to identify improvements for an instructional design theory based on a designed instance of the …

Let's Get Technical-All Hands-On Deck: Collaborating Across Library Units To Tackle Streaming Media Ordering, Stacey Marien, Alayne Mundt, Mary Wahl

Against the Grain

No abstract provided.

Ensuring Access To Government Information, Shari Lasiter, Lynda Kellam

Against the Grain

No abstract provided.

Op Ed-Opinions And Editorials-Educators, Not Engineers, Should Lead The Fight Against Fake News, Adam Blackwell

Against the Grain

No abstract provided.

Table Of Contents

Against the Grain

No abstract provided.

And They Were There-Reports Of Meetings, Ramue K. Kubilius, Sever Bordeianu

Against the Grain

No abstract provided.

If Rumors Were Horses, Katina Strauch

Against the Grain

No abstract provided.

Book Reviews-Monographic Musings, Regina Gong

Against the Grain

No abstract provided.

Legally Speaking-Facing Up To Facebook, William Hannay, Bryan M. Carson, Jack Montgomery, Bruce Strauch

Against the Grain

No abstract provided.

Collecting To The Core-Social Media In Education, Healthcare And Marketing, Anamika Megwalu, Anne Doherty

Against the Grain

No abstract provided.

Profiles Encouraged-Profiles For Many Up And Comers And People, One Company And One Library

Against the Grain

No abstract provided.

End Of Term 2016 Presidential Web Archive, Mark E. Phillips, Kristy K. Phillips

Against the Grain

No abstract provided.

Random Ramblings-Peer Reviewing Of Articles From Third World Countries: My Personal Experience, Bob Holley

Against the Grain

No abstract provided.

State Of State Documents, Susanne Caro

Against the Grain

No abstract provided.

Atg Interviews Jon Cawthorne, Dean Of The University Library System, Wayne State University, Katina Strauch, Tom Gilson

Against the Grain

No abstract provided.

Biz Of Acq-Evidence-Based Collection Development On A Large Scale: A Use Factor Allocation Formula, Michelle Flinchbaugh, Cindy Shirkey

Against the Grain

No abstract provided.

Back Talk-When Your New Best Friend Is A Rattlesnake, Jim O'Donnell

Against the Grain

No abstract provided.

Maintaining Access To Public Data-Lessons From Data Refuge, Margaret Janz

Against the Grain

No abstract provided.

Atg Special Report-The Charlotte Initiative E-Book Symposium, Rebecca Lenzini

Against the Grain

No abstract provided.

Transnational Uses Of Mafia Imagery In Zadie Smith’S White Teeth, Andrea Ciribuco

CLCWeb: Comparative Literature and Culture

In his article "Transnational Uses of Mafia Imagery in Zadie Smith's White Teeth" Andrea Ciribuco discusses the literary representation of multiculturalism in Zadie Smith's first novel, White Teeth (2000). The novel focuses on multicultural encounters in Great Britain in the second half of the twentieth century. This article focuses on one site for these encounters: the character of Millat Iqbal, who joins a gang of teenagers and subsequently a radical Islamic group in his problematic search for identity and belonging. This search is characterized by Millat's tendency to define himself by reference to well-known pop-cultural Mafia figures, whom he …

The Suppression Of Satirizing Belgian Community Difficulties In Flemish Cinema And The Film Adaptation Of Will-O'-The Wisp, Gertjan Willems

CLCWeb: Comparative Literature and Culture

In his article "The Suppression of Satirizing Belgian Community Difficulties in Flemish Cinema and the Film Adaptation of Will-O'-the Wisp" Gertjan Willems analyzes two film projects of Frans Buyens. In 1970, Buyens received a positive funding recommendation for Top-Hit Girl, a satire about community difficulties in Belgium. However, Minister of Culture Frans van Mechelen refused to support the project because it conflicted with his pro-Flemish views. The minister successfully swept this controversial decision under the rug by offering Buyens the option to trade his socially critical project for a film adaptation of Willem Elsschot's novel Will-O'-the Wisp. …

Black Australia ‘Writes Back’ To The Literary Traditions Of Empire, Danica Čerče

CLCWeb: Comparative Literature and Culture

I In her article "Black Australia 'Writes Back' to the Literary Traditions of Empire" Danica Čerče discusses the verse of Australian Indigenous authors Romaine Moreton and Alf Taylor, notable for the overt objection to the institutional and historical processes. These have enabled and maintained the dominant position of those identified as white on the one hand, and the concomitant political, economic, and cultural subordination of Indigenous Australians on the other. Focused on strategies and poetic devices used by the two poets to engage non-Indigenous readers in the experience of their writing, the article examines how the rhetoric of their critique …

Khaled Hosseini’S A Thousand Splendid Suns As A Child-Rescue And Neo-Orientalist Narrative, Abdullah M. Al-Dagamseh, Olga Golubeva

CLCWeb: Comparative Literature and Culture

In their article "Khaled Hosseini's A Thousand Splendid Suns as a Child-Rescue and Neo-Orientalist Narrative" Abdullah Mohammad Dagamseh and Olga Golubeva argue that the novel contrib­utes to hegemonic Eurocentric discourse by showing the superiority and benevolence of the West. In contrast to existing scholarly focus on Hosseini's portrayal of female characters, this article highlights how children of both sexes are represented. The authors' aim is to show how Hosseini's picture of children affected by war contributes to the neo-Orientalist and child-rescue discourses, jus­tifying the foreign involvement in Afghanistan's internal affairs. Moreover, Dagamseh and Golubeva argue that the use of universal …

Voiceless Victims In Sin Tetas No Hay Paraíso, Henry James Morello

CLCWeb: Comparative Literature and Culture

In his article "Voiceless Victims in Sin tetas no hay paraíso" Henry James Morello discusses Gustavo Bolívar's Sin tetas no hay paraiso. The novel is, in Bolívar's words, his way of bringing attention to the problem of young women in Colombia using prostitution in order to pay for plastic surgery a very specific problem facing the youth of Colombia. However, at what price is the success of the novel? Or, rather, who is compromised as a result of this cultural phenomenon? The author may have intended to write a novel that called attention to the problems facing Colombian …

Digital Art History “Beyond The Digitized Slide Library”: An Interview With Johanna Drucker And Miriam Posner, Miriam Kienle

Artl@s Bulletin

Johanna Drucker and Miriam Posner were two of the organizers of the Getty/UCLA Summer Institute in Digital Art History “Beyond the Digitized Slide Library” that took place in the summers of 2014 and 2015. With their extensive expertise in the field, they developed a program that challenged participant to think about the broad theoretical implications of their respective projects and to gain practical tools in digital art history. In this interview, they will describe some of their thinking behind the institute and the state of the field of digital art history, including a discussion of the impact of network visualizations …

“What You See Is What You Get: The Artifice Of Insight”: A Conversation Between R. Luke Dubois And Anne Collins Goodyear, Anne C. Goodyear

Artl@s Bulletin

The metaphorical relationship between sight and knowledge has long been recognized: the double-entendre of “illumination” promises both light and understanding; “I see” signifies that one “gets it” intellectually. This conversation between R. Luke DuBois and Anne Collins Goodyear addresses how data accrues meaning through pictorial structures that represent it. An artist, DuBois has consistently played with conventions for depicting information visually, revealing the intersections between data and desire they represent. Reexamining the interfaces through which we view the world, DuBois and Goodyear consider what our filters threaten to hide.

La relation métaphorique entre la vue et la connaissance a longtemps …

The Computer As Filter Machine: A Clustering Approach To Categorize Artworks Based On A Social Tagging Network, Stefanie Schneider, Hubertus Kohle

Artl@s Bulletin

Image catalogs containing several million reproductions of artworks still pose a costly or computationally intensive challenge if one tries to categorize them adequately, either in a manual or automatic way. Using crowdsourced annotations assigned by laypersons, this article proposes the application of a clustering algorithm to segment artworks into groups. It is shown that the resulting clusters allow for a consistent reclassification extending the traditional categories (history, genre, portrait, still life, landscape), and thus enable a finely-grained differentiation which can be used to search in and filter image inventories, among other things.