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Gmp In The Qc Laboratory And Analytical Method Validation, Stephen Byrn, Zita Ekeocha, Martin Hynes, Roger Ongosi, Kari Clase

The Proceedings of the BIRS Community

This document aims to provide suggestions for course content to the team designing a GMP QC laboratory and analytical method validation course. This course is a 30-minute high-level overview that is part of the USP GMP course.

Investigating Using R, S, And X Charts In Monitoring Performance Of Laboratory Equipment, Mercy Okezue, Stella Ebonine, Amoreen Naluyima, Emeka Akobundu, William Boogere-Wakaalo, Lasisi Olayonu, Rhoda Olayonu, Emanuel Akpan, Abubakar Umar, Kikundwa Emma Mbabazi, Nkem C. Ifudu, Andrew Mukungu, Zita Ekeocha, Stephen Byrn, Kari Clase

The Proceedings of the BIRS Community

Statistical process controls are often used for monitoring processes to identify special causes of variation. Signals generated can assess the operational status of equipment and indicate when corrective action is needed. Control charts are a major tool in statistical process controls used in pharmaceutical manufacturing. It uses graphs as a statistical means of expressing the quality of a process or product. Quality improvement is inversely proportional to variability so that decreasing variabilities in product or process increases quality. Medicines testing laboratories employ various equipment to conduct analysis and generate reports to confirm a sample’s disposition. To ensure data integrity, laboratory …

A Case Study On Completing Work In An Organizational Setting: Getting What You Need From Colleagues, Stacy Hoch, Stephen Byrn, Kari Clase

The Proceedings of the BIRS Community

Analyses in this article are based on data contained in proprietary databases accessible to the author.

Completing complex work in an organizational setting often relies on the cooperation and action of colleagues working together. These can be individuals on the same work team collaborating to accomplish a task, or multiple people working across various groups in an organization for one purpose. In doing so, it is critical that workers complete their work task within the required timeframe in order to meet project timelines. On projects such as these, one person can become a bottleneck that slows down activities downstream. This …

Retired Professor Supports Student Protests, Semoon Chang

KAUPA Letters

No abstract provided.

12 - Researched Argument Essay Reflection, Kristin B. Leaman, E. C. Mcgregor Boyle

Annotated Bibliography Researched Argument Essay

No abstract provided.

8 - Scholarly Article Analysis Peer Review Worksheet, Kristin B. Leaman, E, C, Mcgregor Boyle

Scholarly Article Analysis

No abstract provided.

08 - An Introduction To Mis/Disinformation, Melissa Chomintra

Annotated Bibliography Researched Argument Essay

No abstract provided.

11 - Researched Argument Essay Peer Review Worksheet, Kristin B. Leaman, E. C. Mcgregor Boyle

Annotated Bibliography Researched Argument Essay

No abstract provided.

On Chatgpt: Pedagogical And Academic Musings, John J. Han

KAUPA Letters

No abstract provided.

A Stray Thought On “Happiness”, Yeomin Yoon

KAUPA Letters

No abstract provided.

Effects Of Alternative Hermetic Bag Storage On Fermented And Dried Cocoa Bean (Theobroma Cacao L.), Kenneth Foster, Lina M. Suarez-Guzman, Diana C. Meza-Sepulveda, Dieudonne Baributsa, Carlos A. Zurita

Department of Agricultural Economics Faculty Publications

Cocoa beans, derived from the Cacao Tree (Theobroma cacao L.), are a cash crop among smallholder farmers in tropical regions. After harvest and processing, maintaining cocoa bean quality is critical to access lucrative markets. This paper examines the impact of hermetic storage on insect damage, mold, moisture content, and water activity of fermented and dried cocoa beans under farm conditions in collaboration with a farmer association of Belén de Umbría in Colombia. Three types of hermetic storage systems were assessed for a period of 12 months: Purdue Improved Crop Storage (PICS) bags, including both 2- and 3-layer variants, and Ecotact® …

Perceptual Grouping With Latent Noise, Ben Lonnqvist, Zhengqing Wu, Michael H. Herzog

MODVIS Workshop

Humans effortlessly group elements into objects and segment them from the background and other objects without supervision. For example, the black and white stripes of a zebra are grouped together despite vastly different colors. A thorough theoretical and empirical account of perceptual grouping is still missing – Deep Neural Networks (DNNs), which are considered leading models of the visual system still regularly fail at simplistic perceptual grouping tasks. Here, we propose a counterintuitive unsupervised computational approach to perceptual grouping and segmentation: that they arise because of neural noise, rather than in spite of it. We show that adding noise in …

Modeling The Projection Geometry Of The Retinotopic Visual Hierarchy, Christopher W. Tyler

MODVIS Workshop

No abstract provided.

A Foveated Model Of Visual Discrimination Based On Windowed Texture Statistics, Jan W. Kurzawski, William F. Broderick, Eero P. Simoncelli, Jonathan Winawer

MODVIS Workshop

Most information from visual scenes is discarded by the human nervous system and thus cannot influence visual behavior. Here, we investigated the loss of spatial pattern information. This loss increases dramatically with eccentricity. Recently, models have been developed that average image features in pooling windows whose diameters scale with eccentricity. These models can be used to synthesize “metamers” of natural scenes, images which are physically different but perceptually indistinguishable. Psychophysical experiments have identified the maximum window scaling for which model discrimination abilities match human performance (“critical scaling”). If images are synthesized with pooling windows that exceed critical scaling (“supercritical scaling”), …

Dissecting Bayes: Using Influence Measures To Test Normative Use Of Probability Density Information Derived From A Sample, Laurence T. Maloney, Keiji Ota

MODVIS Workshop

Bayesian decision theory (BDT) is used to model human performance in tasks where the decision maker must compensate for uncertainty in order to gain rewards and avoid losses. BDT prescribes how the decision maker can combine available data, prior knowledge, and value to reach a decision maximizing expected winnings. Do human decision makers actually use BDT in making decisions? Researchers typically compare overall human performance (total winnings or overall percent correct) to the predictions of BDT but we cannot conclude that BDT is an adequate model for human performance based on just overall performance. We break BDT down into elementary …

Information Theory Representation Of Perceptual Processes, Misha Pavel, Yorgos Stratis, Holly B. Jimison, Karen S. Quigley, Deniz Erdogmus

MODVIS Workshop

Human performance in many visual experiments is assessed using probabilities of specific responses to uncertain visual events. Using signal detection theory with specific distributional assumptions, we frequently represent the combination of correct detections with correct negative responses to estimate with measures of discriminability, d', and a response criterion. A shortcoming of this approach involves limitations in generalizing the performance measures across different tasks, especially in experiments with dual or multiple tasks that require comparisons of the performance of simultaneous tasks. Our research aims to develop a framework enabling us to estimate the cognitive resources allocated to different tasks.

We propose …

Algebraic Speed Estimation For Sensorless Induction Motor Control: Insights From An Electric Vehicle Drive Cycle, Jorge Neira-Garcia, Andres Beltran-Pulido, John Cortes-Romero

Purdue University Libraries Open Access Publishing Fund

Induction motors (IMs) must meet high reliability and safety standards in mission-critical applications, such as electric vehicles (EVs), where sensorless control strategies are fundamental. However, sensorless rotor speed estimation demands improvements to overcome filtering distortions, tuning complexities, and sensitivity to IM model mismatch. Algebraic methods offer inherent filtering capabilities and design flexibility to address these challenges without introducing additional dynamics into the control system. The objective of this paper is to provide an algebraic estimation strategy that yields an accurate rotor speed estimate for sensorless IM control. The strategy includes an algebraic estimator with single-parameter tuning and inherent filtering action. …

Exploring Inventions In Self-Directed Language Learning With Generative Ai: Implementations And Perspectives Of Youtube Content Creators, Belle Li, Chaoran Wang, Curtis J. Bonk, Xiaojing Kou

Department of Curriculum and Instruction Faculty Publications

This study explores the integration of generative AI, specifically ChatGPT, in selfdirected language learning (SDLL) as perceived by YouTube content creators. Through thematic analysis of in-depth interviews with 14 prominent online language educators with related YouTube videos on ChatGPT, the present study investigates: (1) their perceptions of GenAI as a tool for SDLL, (2) strategies that they recommend to effectively utilize ChatGPT for enhancing SDLL, and (3) the guidelines they suggest for fostering SDLL with AI. The findings show that YouTube-based language educators acknowledged ChatGPT as a vital tool for SDLL as it offers availability, versatility, and transformative potential. Besides …

Second Reaction: Letters To A Prisoner, Polly Parkinson

First Opinions, Second Reactions

No abstract provided.

The Mechanism By Which Thermal Coupling Leads To An Asymptotic Maldistribution Stability Boundary For Flow Boiling In Parallel Microchannels, Md Emadur Rahman, Justin A. Weibel

CTRC Research Publications

Phase change heat transfer processes are attractive for the efficient thermal management of advanced semiconductor devices, with flow boiling in parallel microchannel heat sinks being one promising solution. However, there are several implementation challenges associated with two-phase flow in parallel microchannels, particularly flow maldistribution, which can adversely affect performance and reliability. Two-phase flow models can be useful in predicting and understanding the instability mechanisms that leads to maldistribution, such that parametric performance trends and safe regions of operation can be identified. Channel-to-channel thermal coupling has been shown to alleviate maldistribution, but it is not yet understood why this effect is …

Centerless? Making Sense Of Disruptions In The Graduate Writing Center, Shannon Mcclellan Brooks

The Writing Center Journal

This critical self-reflection is not a success story; rather, it is an effort of decolonial thinking that reckons with the idea, experience, and practice of centerlessness during pandemic-induced online transitions and operations in a graduate writing center (GWC). By tracing the contours of a series of interlocking disruptions the author and her graduate writing center community experienced during COVID-19, this article brings into sharp focus present colonial legacies inhibiting effective developments, moves, and adaptations to the GWC physical center space and praxis. Through retrospectively following pandemic-induced disruptions to her center, the author critically engages how epistemologies of coloniality and modernity …

Re/Searching (For) Hope: Archives And (Decolonizing) Archival Impressions, Romeo Garcia

The Writing Center Journal

On archives and archival impressions, this essay extends archival research to the elsewhere and otherwise. The essay asks, how do we reposition the contents of archives so that we can position ourselves in relation to it otherwise? It puts forward a theory of (decolonizing) archival impressions.

Reconceptualizing Self-Directed Learning In The Era Of Generative Ai: An Exploratory Analysis Of Language Learning, Belle Li, Curtis J. Bonk, Chaoran Wang, Xiaojing Kou

Department of Curriculum and Instruction Faculty Publications

This exploratory analysis investigates the integration of ChatGPT in self-directed learning (SDL). Specifically, this study examines YouTube content creators’ language-learning experiences and the role of ChatGPT in their SDL, building upon Song and Hill's conceptual model of SDL in online contexts. Thematic analysis of interviews with 19 YouTubers and relevant video contents reveals distinct constructs of ChatGPT-integrated SDL, suggesting a reconceptualization and refinement of the SDL framework in the consideration of generative artificial intelligence (AI). This framework emphasizes critical aspects of utilizing ChatGPT as an SDL tool on two distinct levels: 1) the interactive relationships and interplay between learners’ personal …

The Ugliness Movement: Riot Grrrl's Use Of Ugliness As Feminist Subversion, Maylee Rollins

The Purdue Historian

In the 1990s, Riot Grrrl took the punk and feminist worlds by storm. It emphasized community and represented third-wave feminism in radical form. One particular example that represents the Riot Grrrl ideology well is ugliness. Throughout the movement, artists like Courtney Love and Kathleen Hanna used their musical platform to show the world their view of femininity. This involved body writing and reclaiming words used to degrade women, as well as dressing up in controversial outfits dubbed as “kinderwhore.” The aims of these women in using ugliness in their music were to subvert sexism in the punk scene and bring …

Where To Test A Nuclear Bomb, Tyler Kliegl

The Purdue Historian

The United States detonated three underground nuclear bombs on a far-off Alaskan island called Amchitka in the 1960s and 70s. The goal is to understand what the motive of the United States in selecting Amchitka over the endless potential sites to test at were. What makes a place worthy in being tested on, or unworthy in being left alone. How does the United States deal with resistance from locals and other organizations, fighting to prevent their tests.

The American West And Nozick’S Theory Of Entitlements, Kaitlyn E. Price

The Purdue Historian

Customary law emphasizing the protection of private property rights rather than the authoritative assertion of the law characterized expansion into the American West from 1848-1895. The subsequent legal systems developed in a minarchistic manner that aligned with Robert Nozick’s “theory of entitlements,” leading to the adoption of a “night-watchman state.” This theory asserts that a society built upon customary law that focuses on the protection of individual rights will undoubtedly develop a protective body to safeguard these rights in pursuit of the third principle, the “rectification of justice.” Thus, the chaotic and often disorganized way the West’s extralegal and formal …

Sparse Ensemble Networks For Hypserspectral Image Classification, Rakesh Kumar Iyer, Okan Ersoy

Department of Electrical and Computer Engineering Technical Reports

We explore the efficacy of sparsity and ensemble model in the classification of hyperspectral images, a pivotal task in remote sensing applications. While Convolutional Neural Networks (CNNs) and Transformer models have shown promise in this domain, each exhibits distinct limitations; CNNs excel in capturing the spatial/local features but falter to capture spectral features, whereas Transformers captures the spectral features at the expense of spatial features. Furthermore, the computational cost associated with training several independent CNN and Transformer networks becomes expensive. To address these limitations, we propose a novel ensemble framework comprising pruned CNNs and Transformers, optimizing both spatial and spectral …

Achieving Room Temperature Plasticity In Brittle Ceramics Through Elevated Temperature Preloading, Chao Shen, Jin Li, Tongjun Niu, Jaehun Cho, Zhongxia Shang, Yifan Zhang, Anyu Shang, Bo Yang, Ke Xu, R. Edwin Garcia, Haiyan Wang, Xinghang Zhang

Purdue University Libraries Open Access Publishing Fund

Ceramic materials with high strength and chemical inertness are widely used as engineering materials. However, the brittle nature limits their applications as fracture occurs before the onset of plastic yielding. There has been limited success despite extensive efforts to enhance the deformability of ceramics. Here we report a method for enhancing the room temperature plastic deformability of ceramics by artificially introducing abundant defects into the materials via preloading at elevated temperatures. After the preloading treatment, single crystal (SC) TiO2 exhibited a substantial increase in deformability, achieving 10% strain at room temperature. SC α-Al2O3 also showed plastic deformability, 6 to 7.5% …

Detection And Characterization Of Copy Number Variation In Three Differentially-Selected Nellore Cattle Populations, Lorena F. Benfica, Luiz F. Brito, Ricardo D. Do Bem, Leticia F. De Oliveira, Henrique A. Mulim, Larissa G. Braga, Joslaine N.S.G. Cyrillo, Sarah F.M. Bonilha, Maria Eugenia Z. Mercadante

Purdue University Libraries Open Access Publishing Fund

Introduction: Nellore cattle (Bos taurus indicus) is the main beef cattle breed raised in Brazil. This breed is well adapted to tropical conditions and, more recently, has experienced intensive genetic selection for multiple performance traits. Over the past 43 years, an experimental breeding program has been developed in the Institute of Animal Science (IZ, Sertaozinho, SP, Brazil), which resulted in three differentially-selected lines known as Nellore Control (NeC), Nellore Selection (NeS), and Nellore Traditional (NeT). The primary goal of this selection experiment was to determine the response to selection for yearling weight (YW) and residual feed intake (RFI) on Nellore …

Cross-Sectional Study Of Personal Protective Equipment Use, Training And Biosafety Preparedness Among Healthcare Workers During The First Months Of The Sars-Cov-2 Pandemic In Brazil, Kerstin Muner, Julia Kilgour, Tatiana Ometta, Ana Perola Drulla Brandao, Andrea Pires Dos Santos, Ana Marcia Sa Guimaraes

Purdue University Libraries Open Access Publishing Fund

Objectives Brazil has high rates of COVID-19 and tuberculosis among healthcare workers (HCWs). Personal protective equipment (PPE) is essential for their protection. We aimed to evaluate PPE use, training, and preparedness among HCWs in the early months of the SARS-CoV-2 pandemic in Brazil.

Methods A cross-sectional study was performed using questionnaires available to HCWs through a website created to provide PPE guidelines. χ2 test and robust Poisson regression identified factors associated with HCWs treating COVID-19 patients (TCOVID-19), lack of training on PPE use and N95 respirator reuse. The speech content of open-ended questions was analysed.

Results We analysed 1410 questionnaires …