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21st Century Learning Ecosystem Opportunities Convening, 21cleo Research Team

21CLEO Presentations and Publications

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Mechanisms Of Substrate Recognition By The Cul3-Based E3 Ligase, Katia Graziella De Oliveira Rebola

Dissertations and Theses

Cul3-based E3 ligase is responsible for regulating a variety of cellular pathways, many of which are known to have profound effects on the proper function of multicellular organisms. Although progress over the past years has been truly impressive, our understanding of the mechanisms of E2 recruitment and selection by the BCR complex and all the roles that Cul3 plays on kidneys remains in its infancy. To explore these aspects, this dissertation aims to analyze the Cul3 complex using two different approaches: (1) We used the powerful tool of chimeric analysis to map the essential domain binding characteristics of Cul3 taking …

What’S Left Before Participatory Modeling Can Fully Support Real-World Environmental Planning Processes: A Case Study Review, Beatrice Hedelin, S. Gray, S. Woehlke, Todd K. Bendor, Alison Singer, R. Jordan, Moira Zellner, Philippe J. Giabbanelli, Pierre D. Glynn, Antoine J. Jetter, Multiple Additional Authors

Engineering and Technology Management Faculty Publications and Presentations

In environmental participatory modeling (PM), both computer and non-computer-based modeling techniques are used to aid participatory problem description, solution, and decision-making actions in environmental contexts. Although many PM case studies have been published, few efforts have sought to systematically describe and understand dominant PM processes or establish best practices for PM. As a first step, we have reviewed a random sample of environmental PM case study articles (n = 60) using a novel PM process evaluation instrument. We found that significant work likely remains for PM to fully support participatory and integrated planning processes. While PM reports systematically address knowledge …

Global Evidence Of Constraints And Limits To Human Adaptation, Adelle Thomas, Emily Theokritoff, Alexandra Lesnikowski, Diana Reckien, Kripa Jagannathan, Roger Cremades, Donovan Campbell, Elphin Tom Joe, Asha Sitati, Idowu Ajibade, Multiple Additional Authors

Geography Faculty Publications and Presentations

Constraints and limits to adaptation are critical to understanding the extent to which human and natural systems can successfully adapt to climate change. We conduct a systematic review of 1,682 academic studies on human adaptation responses to identify patterns in constraints and limits to adaptation for different regions, sectors, hazards, adaptation response types, and actors. Using definitions of constraints and limits provided by the Intergovernmental Panel on Climate Change (IPCC), we find that most literature identifies constraints to adaptation but that there is limited literature focused on limits to adaptation. Central and South America and Small Islands generally report greater …

Black Children's Development Of Self-Regulation Within Stressful Contexts Of Parenting: Investigating Potential Buffering Effects Of A Kindergarten Social-Emotional Learning Program, Eli Labinger

Dissertations and Theses

Children living in poverty are at an elevated risk for experiencing academic, social-emotional, and behavioral difficulties when beginning kindergarten, and early educational achievement gaps between economically disadvantaged and advantaged children are known to persist and widen over time. Black children face additional challenges related to racism, marginalization, minoritization, and oppression--processes which may, like poverty, impact their development by affording them fewer of the high-quality experiences that are critical for early learning. Fortunately, evidence-based social-emotional learning (SEL) programs offer tools to promote the social-emotional and behavioral competencies that support children's school readiness and early learning, and may counteract the adverse impacts …

Rhyolite Stratigraphy Along Succor Creek: Insights Into The Eruptive History Of The Three Fingers And Mahogany Mountain Volcanic Field, Cassandra Caryl Black

Dissertations and Theses

The Mahogany Mountain and Three Fingers calderas with their associated tuffs, the tuff of Leslie Gulch and tuff of Spring Creek, respectively, were the centerpiece of a larger rhyolite center that developed in response to Columbia River Basalt volcanism as numerous other mid Miocene rhyolite centers in a corridor from Baker City in the north to northern Nevada. Previous studies suggest a two caldera model, while others advocated for a single large caldera producing solely the tuff of Leslie Gulch. This study refines the eruptive stratigraphy along the northeastern margin of this rhyolite field with important implications for the entire …

Investigation Of Environmental-Friendly, Membraneless Hydrogen Peroxide Fuel Cells, Bao Nguyen

Dissertations and Theses

Human-induced climate change is one of the biggest threats to humanity in the 21^st century. This is caused by the increase in greenhouse gas concentrations in the Earth's atmosphere. The burning of fossil fuels is the primary cause of climate change. This problem can be addressed by replacing fossil fuels with fuel sources that have clean by-products and are cost-effective. For the last few decades, hydrogen (H₂) has been extensively studied as an alternative to carbon-based fossil fuels. Currently, H₂ still has many shortcomings for commercial applications. The photocatalytic production of H₂ still suffers from …

Climate Change Will Increase The Vector Capacity Of The Aedes Aegypti In South America: A Systematic Map, Liliana I. Maz, Richard S. Lockwood

PSU McNair Scholars Online Journal

Tropical infectious diseases such as dengue, chikungunya, and Zika affect millions of people annually in all regions of the world. The disease burden propagated by these arboviruses has rapidly increased in recent decades due to the range expansion of their shared vector, the Aedes aegypti mosquito. The IPCC has predicted a global increase in temperatures of 1.4-5.8°C over the next century; understanding how that will affect the vector capacity of the Aedes aegypti is essential for public health planning. This paper examined findings from a systematic map of the current state of research on this increasingly important influence on infectious …

Multi-Scale Environmental Conditions Associated With Shade-Tolerant Conifer Regeneration In Forest Park, Portland, Oregon, Matthew Cook

Dissertations and Theses

Forest Park is a 5,100-acre urban forest located in Portland, Oregon, that has been impacted by various anthropogenic stressors including logging, fragmentation, invasive species, air pollution and recreation use due to its proximity to the urban environment. This legacy of land use coupled with natural disturbances has resulted in changes to forest structure, composition, and function--threatening the long-term sustainability of the park. Past research in Forest Park has identified a lack of regenerating shade-tolerant conifers, particularly western hemlock and western red cedar species, in the section of the park closest to the city. Typically, western hemlock and western red cedar …

Exploring Mirna Function And Host Response To Coxiella Burnetii Infection, Madhur Sachan

Dissertations and Theses

Alveolar macrophages attempt to control bacterial infection through a spectrum of defense processes, including induction of apoptosis, autophagy, inflammatory response, and nutrient sequestration. MicroRNAs (miRNAs), a class of small non-coding RNAs, are involved in a spectrum of physiological processes, including immune response to intracellular infections. However, whether microRNAs have any functions in host response to Coxiella burnetii infection is unknown. Coxiella burnetii is a highly infectious intracellular pathogen that causes Q fever, a zoonosis with a worldwide occurrence. In this work, I investigated the functions of miRNAs in host response to C. burnetii infection and found that miRNAs are an …

Spatial Analysis Of Landscape Characteristics, Anthropogenic Factors, And Seasonality Effects On Water Quality In Portland, Oregon, Katherine Gelsey, Daniel Ramirez

REU Final Reports

Urban areas often struggle with deteriorated water quality as a result of complex interactions between landscape factors such as land cover, use, and management as well as climatic variables such as weather, precipitation, and atmospheric conditions. Green stormwater infrastructure (GSI) has been introduced as a strategy to reintroduce pre-development hydrological conditions in cities, but questions remain as to how GSI interacts with other landscape factors to affect water quality. We conducted a statistical analysis of six relevant water quality indicators in 131 water quality stations in four watersheds around Portland, Oregon using data from 2015 to 2021. Indiscriminate of station …

Adoption And Use Of E-Grocery Shopping In The Context Of The Covid-19 Pandemic: Implications For Transport Systems And Beyond, Gabriella Abou-Zeid

Dissertations and Theses

In 2020, the COVID-19 pandemic drastically impacted travel for in-person shopping, commute trips, global supply chains, and food business operations. Previously mundane tasks, like shopping for food and household items, became markedly different as new social distancing and mask guidelines were put in place to mitigate the spread of COVID-19. Concurrently, e-commerce sales in the U.S. skyrocketed. E-grocery pickup and delivery services saw unprecedented expansions. The adoption and use of e-grocery services have implications for equity and mobility, although the nature of the relationship of e-grocery to the latter is still unclear. Enhancing our understanding of the drivers of (and …

Mechanistic Investigation Of Neuropeptide S-Nitrosylation By Nitric Oxide Moieties: A Kinetic And Thermodynamic Approach, Vusumuzi Leroy Sibanda

Dissertations and Theses

This dissertation focuses on providing quantitative insights regarding kinetic, thermodynamic and mechanistic parameters of neuropeptide S-nitrosylation by nitrous acid (HNO₂), peroxynitrite (ONOO^-) and S-nitroso-N-acetyl-D,L-penicillamine (SNAP) to produce S-nitrosothiols (SNOs). Peptide thiol stability and the formation of SNOs from neuropeptides; arginine vasopressin (AVP), somatostatin-14 (SST-14) and urotensin II (U-II) was studied. Investigations into the effects of temperature, copper chelators and pH on peptide thiol autoxidation show that AVP, SST-14 and U-II thiols have half-lives of 30, 44 and 28.2 mins respectively at physiologically relevant temperature and pH in the absence of metal chelators. Target peptide thiols were …

Automated Statistical Structural Testing Techniques And Applications, Yang Shi

Dissertations and Theses

Statistical structural testing(SST) is an effective testing technique that produces random test inputs from probability distributions. SST shows superiority in fault-revealing power over random testing and deterministic approaches since it heritages the merits from both of them. SST ensures testing thoroughness by setting up a probability lower-bound criterion for each structural cover element and test inputs that exercise a structural cover element sampled from the probability distribution, ensuring testing randomness. Despite the advantages, SST is not a widely used approach in practice. There are two major limitations. First, to construct probability distributions, a tester must understand the underlying software's structure, …

The Effect Of A Ferrite-Core Relay Vs. An Air-Core Relay On The Output Power Characteristics Of A Three-Coil Wireless Power Transfer System, Jakob L. White

University Honors Theses

The purpose of this thesis is to determine the effect of using a ferrite-core relay on the output power characteristics of a three-coil, parallel-tuned, domino-resonator wireless power transfer (WPT) system in comparison to the effect of using an air-core relay in such a system. First, a general mathematical model is presented to describe both the ferrite-core-relay system and the air-core-relay system and to calculate their output power characteristics for seven different resistive loads at each of five different distance configurations between the coils. Next, experimental results are analyzed and compared to the mathematical results to confirm model accuracy. Finally, the …

Time To Re-Evaluate Taniguchi Jiro's Pace In Manga, Natsume Fusanosuke, Jon Holt, Teppei Fukuda

World Languages and Literatures Faculty Publications and Presentations

Natsume Fusanosuke is Emeritus Professor of the Graduate Program of Cultural Studies in Corporeal and Visual Representation, Gakushūin University. Despite his recent retirement from Gakushūin in March, he is still very active in manga criticism and scholarship. Originally a manga artist himself in the 1980s, by the 1990s he began doing more writing about manga, although he often still employs his cartooning skills to assist in his analysis and explanation of his subjects, much like his American contemporary Scott McCloud. It is not a stretch to compare the latter’s Understanding Comics to Natsume's work in the classic How to Read …

Understanding The Metabolic Regulation Of Trained Immunity By Palmitic Acid, Khaleda Aqaei, Brooke A. Napier

McNair Symposium

Sepsis is an inflammatory disease that occurs when the body’s response to an infection becomes dysregulated, and infection-fighting processes of the body damage tissues via inflammation, resulting in organ failure and death. Currently, the role for diet in regulating sepsis susceptibility and severity is not fully understood. The Western Diet (WD), the most prevalent diet worldwide, is high in saturated fatty acids (SFAs) and sucrose, and low in fiber. Previously, we have used a lipopolysaccharide (LPS)-induced sepsis mouse model to show that mice fed a Western Diet (WD) or a diet enriched only in SFAs (Ketogenic Diet; KD), experience increased …

Perceptual Mismatch Between Meso And Macro Policy At Tokyo International University, Brianna Ross, Kimberly Brown

McNair Symposium

Previous studies have aimed at looking at meso and micro policy levels of Japanese educational institutions and their English language teaching programs. Through conducting surveys and interviews, researchers gained knowledge of how, or if, institutions portray their standards to students and staff and how those goals are displayed through curriculum. This research shows a disconnect between the stated goals and in class instruction. While the researchers looked at overall disconnects, none looked at specific universities and their programs. My study aims to fill that gap, focusing on a university known for its English teaching and production skills. The intention is …

Liberalism, Settlement, Sacrifice: Towards A Genealogy Of Sacrificial Politics, Marshall Scheider, Adam Culver

McNair Symposium

In recent years, political theorists have begun to explore the sacrificial dimensions of liberalism and neoliberalism in the global North. Little of this work, however, grapples with the ways settler colonialism informs contemporary political sacrifice or conceptions of the sacrificial. This paper traces a genealogy of contemporary political sacrifice through the archive of early British colonialism in North America. When theorists ignore this archive, they do more than render colonization mute: they also fail to apprehend what I term political sacrifice’s differential function—the mechanism by which sacrifice’s burdens fall on subordinated groups while its benefits accrue to the socially, politically, …

Efficacy Of Curcumin In Asthma: A Systematic Review And Meta Analysis, Tabitha Grow, Adam Sadowski

McNair Symposium

Over 23 million people are affected by asthma in the United States and 262 million individuals globally. Asthma, if poorly controlled, is associated with significant morbidity as well as increased risk for mortality. Asthma involves several complex inflammatory pathways and processes including an increase in immune cell activation. Curcumin, the active constituent found in turmeric, has been studied in numerous in-vivo and in-vitro studies to generate anti-inflammatory effects in pulmonary diseases and, more recently, an increase in clinical data has become available. Since the most recent review assessing the role of curcumin in pulmonary disorders, additional clinical trials have been …

Ronald E. Mcnair Scholars Program Profiles And Abstracts 2021, Mcnair Scholars Program

McNair Symposium

This is the complete event program and provides presentation abstracts and biographies of McNair scholars and their mentors.

Physical Activity As A Mediator Between Race/Ethnicity And Changes In Multimorbidity., Jason T. Newsom, Emily C. Denning, Miriam R. Elman, Anda Botoseneanu, Heather G. Allore, Corey L. Nagel, David A. Dorr, Ana R. Quiñones

Psychology Faculty Publications and Presentations

Studies report racial/ethnic disparities in multimorbidity (≥2 chronic conditions) and their rate of accumulation over time as well as differences in physical activity. Our study aimed to investigate whether racial/ethnic differences in the accumulation of multimorbidity were mediated by physical activity among middle-aged and older adults.

Quantum Grover's Oracles With Symmetry Boolean Functions, Peng Gao

Dissertations and Theses

Quantum computing has become an important research field of computer science and engineering. Among many quantum algorithms, Grover's algorithm is one of the most famous ones. Designing an effective quantum oracle poses a challenging conundrum in circuit and system-level design for practical application realization of Grover's algorithm.

In this dissertation, we present a new method to build quantum oracles for Grover's algorithm to solve graph theory problems. We explore generalized Boolean symmetric functions with lattice diagrams to develop a low quantum cost and area efficient quantum oracle. We study two graph theory problems: cycle detection of undirected graphs and generalized …

Discarded Identities/Inspiring Just Sustainability With Reuse Persona Dolls, Michelle A. Domingues

Education Faculty Publications and Presentations

The author identifies as a mixed-race Chicana teacher/educator, bridging ecology, culture, and learning situated within an early learning center on a university campus. This inquiry integrates Gloria Anzaldúa’s autohistoria teoría/autobiographical theory and documents (1) the social construction of a gender-fluid persona doll named “Logan” during a focus group with REMIDA Reggio-inspired educators, (2) a (dis)rupture that took place after engaging the persona doll to introduce the term “transgender” during a preschool circle time, and (3) lessons learned to move early childhood education for social sustainability forward. During this disrupture in our learning community, the question of whether or not to …

Microbes On The Mountain: Plant-Microbe Associations And Interactions On Mount St. Helens, Emily Rose Wolfe

Dissertations and Theses

Plant-microbe associations and interactions provide critical context to studies in both community and ecosystem ecology, especially in systems that are relatively new and still undergoing early successional processes. Microbes can colonize the surfaces and interiors of all plant tissues, and these assemblages vary in composition both spatially and temporally, even within the same plant. Endophytes are bacteria or fungi that spend most of their lifecycles living within plant tissues asymptomatically--typically, "endophyte" refers specifically to aboveground tissues such as leaves and stems, and therefore may have direct influences on defenses against herbivory, pathogen or pest tolerance, and even afterlife effects on …

A Multiplicity Of Journeys: Stem Education Ecosystems As Sources Of Cultural Sustenance, Christopher Louis Beauprey Cardiel

Dissertations and Theses

In this document, I outline the context and significance of a research problem faced by both formal and informal science, technology, engineering, and math (STEM) educators in the Portland metro area--specifically, the need for greater understanding of the individual and cultural motivations, needs, and agentic behavior of learners, as well as the ways in which these factors intersect with learners' experiences of cultural sustenance within their holistic STEM education ecosystems. I base the significance of this problem on the racial and gender inequities evident in the STEM fields and the social and cultural dynamics that discourage members of these groups …

Proximal Policy Optimization For Radiation Source Search, Philippe Erol Proctor

Dissertations and Theses

Rapid localization and search for lost nuclear sources in a given area of interest is an important task for the safety of society and the reduction of human harm. Detection, localization and identification are based upon the measured gamma radiation spectrum from a radiation detector. The nonlinear relationship of electromagnetic wave propagation paired with the probabilistic nature of gamma ray emission and background radiation from the environment leads to ambiguity in the estimation of a source's location. In the case of a single mobile detector, there are numerous challenges to overcome such as weak source activity, multiple sources, or the …

Experiences Of Undergraduates And Graduate Teaching Assistants In Biology Course-Based Undergraduate Research Experiences, Emma Crystal Goodwin

Dissertations and Theses

Evidence of positive student outcomes from course-based undergraduate research experiences (CUREs) has sparked implementation of CUREs in introductory biology laboratory courses, as one approach to boosting student engagement in research. In a CURE, students collaborate with other students and instructors on a research project, where they conduct novel scientific research that has relevance to a local or scientific community. However, previous research rarely considers that graduate teaching assistants (GTAs) often teach introductory labs. The classroom role of GTAs expands in a CURE--they no longer need to simply teach a lab class, but also to serve as research mentors. GTAs, who …

Information Security Maturity Model For Healthcare Organizations In The United States, Bridget Joan Barnes Page

Dissertations and Theses

This research provides a maturity model for information security for healthcare organizations in the United States. Healthcare organizations are faced with increasing threats to the security of their information systems. The maturity model identifies specific performance metrics, with relative importance measures, that can be used to enhance information security at healthcare organizations allowing them to focus scarce resources on mitigating the most important information security threat vectors. This generalizable, hierarchical decision model uses both qualitative and quantitative metrics based on objective goals. This model may be used as a baseline by which to measure individual organizational performance, to measure performance …

"Like I Was An Actual Researcher": Participation And Identity Trajectories Of Underrepresented Minority And First-Generation Stem Students In Research Training Communities Of Practice, Jennifer Lynn Lindwall

Dissertations and Theses

Although calls for a more diverse workforce in biomedical fields have been widespread, racial and ethnic gaps in biomedical degree attainment remain. Contextualist perspectives seek to understand persistent STEM inequities by examining person-in-context experiences and how systemic factors filter into students' proximal contexts shaping their participation and science identity trajectories. Research training communities of practice aim to offer underrepresented minority and first-generation students support, guidance, and opportunities to learn the practices of science and construct their science identity. However, many students still choose to leave these programs. There is limited research on these students' science identity construction process and their …