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Threats To Democracy: A Danger To Social Justice For All, José Luis Irizarry, Rajade M. Berry-James, Duchess D. Humphrey, Rachel Emas, Bruce D. Mcdonald Iii, James Nordin, Michael Lee, Lindsey L. Evans, Anthony M. Starke Jr., Jay M. Grosflam Jan 2025

Threats To Democracy: A Danger To Social Justice For All, José Luis Irizarry, Rajade M. Berry-James, Duchess D. Humphrey, Rachel Emas, Bruce D. Mcdonald Iii, James Nordin, Michael Lee, Lindsey L. Evans, Anthony M. Starke Jr., Jay M. Grosflam

School of Public Service Faculty Publications

This essay argues that threats to democracy—both global and domestic—pose an existential risk to the advancement of social justice. It explores how democratic backsliding undermines efforts to achieve social justice for all, examining anti-democratic practices such as misinformation, voter suppression, institutional dismantling, and the politicization of public service. Highlighting the interdependence between democratic institutions and social equity in public governance, the authors propose a multilevel response framework to foster democratic resilience through civic engagement, institutional accountability, and collective action. In this essay, members of the Board of the Section on Democracy and Social Justice (DSJ) of the American Society for …


'I Did Not Know We Could Exercise This Small Premature Baby': Challenges Experienced By Parents While Implementing Early Intervention For Their Preterm Infants-A Qualitative Perspective, Manasa Kolibylu Raghupathy, Selim Jahangir, Sonia Khurana, Leslie Edward S. Lewis, Bhamini Krishna Rao Jan 2025

'I Did Not Know We Could Exercise This Small Premature Baby': Challenges Experienced By Parents While Implementing Early Intervention For Their Preterm Infants-A Qualitative Perspective, Manasa Kolibylu Raghupathy, Selim Jahangir, Sonia Khurana, Leslie Edward S. Lewis, Bhamini Krishna Rao

Rehabilitation Sciences Faculty Publications

Background

Preterm birth is a highly stressful experience for both parents and infants. Parental participation in care enhances developmental outcomes, fosters parent-infant interactions and builds parental confidence. However, low parental adherence has always been a challenge in the successful implementation of intervention programs both in the NICU and at home. It is imperative to understand parents' perspectives and view the challenges that they experience through their lens while providing early intervention to their infants born preterm. This study is aimed at identifying new parents' challenges when implementing early intervention programs for their infants during the transition from hospital to home. …


Perceptions Of Leadership Opportunities And Effectiveness Among Athletic Trainers: A Comparison Across Racial And Ethnic Groups, Nicolette A. Harris, Americus H. Williams, Julie M. Cavallario, Cailee E. Welch Bacon Jan 2025

Perceptions Of Leadership Opportunities And Effectiveness Among Athletic Trainers: A Comparison Across Racial And Ethnic Groups, Nicolette A. Harris, Americus H. Williams, Julie M. Cavallario, Cailee E. Welch Bacon

Rehabilitation Sciences Faculty Publications

Context

Diverse representation in athletic training leadership is essential for fostering inclusion and innovation in the profession. Despite efforts to enhance leadership diversity, disparities persist, underscoring the need to explore barriers to leadership and the effectiveness of leadership in meeting the needs of athletic trainers (ATs).

Objective

To examine racial and ethnic differences in ATs' desire, pursuit, and attainment of leadership positions in the profession in addition to perceptions of current leadership effectiveness.

Design

Cross-sectional, web-based survey.

Participants

A purposeful sample of 1,173 racially and ethnically diverse ATs from an organized professional network followed by a random sample of 6,000 …


Salary Negotiation Dynamics For Athletic Trainers: Insights From Employers On Expectations And Organizational Influences, Julie M. Cavallario, Forrest Andrews, Kendallyn Johnson, Katherine Schalk, Cailee E. Welch Bacon Jan 2025

Salary Negotiation Dynamics For Athletic Trainers: Insights From Employers On Expectations And Organizational Influences, Julie M. Cavallario, Forrest Andrews, Kendallyn Johnson, Katherine Schalk, Cailee E. Welch Bacon

Rehabilitation Sciences Faculty Publications

Context

While researchers have previously identified that most athletic trainers (ATs) do not negotiate their salary, little is known about employers' expectations and behaviors relative to establishing and negotiating salaries for the ATs they hire.

Objective

To examine employers' expectations and behaviors regarding AT salary negotiation.

Design

Cross-sectional.

Setting

Web-based survey.

Patients or other participants

413 employers who are in a role that requires them to negotiate salary offers with prospective AT employees and who have minimally hired one AT into the organization they work for accessed the survey from a random sample of 7,000 ATs (6% access rate); 324 …


Case Report: Multifactorial Intervention For Safe Aging In Place, Ashwini Kulkarni Jan 2025

Case Report: Multifactorial Intervention For Safe Aging In Place, Ashwini Kulkarni

Rehabilitation Sciences Faculty Publications

Background/Objectives: Falls are a leading cause of morbidity in older adults, particularly those with multiple comorbidities. A multidisciplinary approach addressing physical, psychological, and environmental factors is essential for reducing fall risk and supporting aging in place. This report evaluates the effectiveness of a multidisciplinary, multifactorial approach in managing high fall risk in an older adult with diabetes, hypertension, and osteoporosis. Methods: A 72-year-old woman with a recurrent history of falls participated in an 8-week intervention as part of the American Physical Therapy Association (APTA) balance and falls prevention credential program. This study was conducted in Virginia Beach, USA, at the …


Therapy-Based Strategies To Support Tummy Time In Infants Post-Hospital Discharge: A Scoping Review Protocol, Ketaki Inamdar, Sonia Khurana Jan 2025

Therapy-Based Strategies To Support Tummy Time In Infants Post-Hospital Discharge: A Scoping Review Protocol, Ketaki Inamdar, Sonia Khurana

Rehabilitation Sciences Faculty Publications

Tummy time is essential for infant development, yet many caregivers face significant challenges with adherence due to behavioral and contextual barriers. While numerous tummy time interventions exist, a limited understanding of their behavioral components hinders effective replication and implementation. This scoping review aims to identify multidisciplinary interventions used to promote tummy time in infants aged 0–12 months, evaluate their impact on adherence, developmental and health outcomes, and examine the behavior change techniques employed using the Theoretical Domains Framework (TDF). Following the Joanna Briggs Institute (JBI) methodology, a comprehensive search will be conducted in MEDLINE (PubMed), Web of Science Core Collection, …


Comparing Immersive And Nonimmersive Clinical Experiences In Athletic Training Education: Effects On Student Engagement And Confidence, Julie M. Cavallario, Shana Pribesh, S. E. Walker Jan 2025

Comparing Immersive And Nonimmersive Clinical Experiences In Athletic Training Education: Effects On Student Engagement And Confidence, Julie M. Cavallario, Shana Pribesh, S. E. Walker

Rehabilitation Sciences Faculty Publications

Context

With the shift to a graduate-level professional degree in athletic training, it was hypothesized that immersive clinical experiences (ICEs) would be more effectively integrated into curricula than non-ICEs (N-ICEs) and better prepare students for practice.

Objective

To longitudinally compare clinical engagement opportunities in ICEs versus N-ICEs and assess if these opportunities are associated with changes in student confidence in performing related tasks.

Design

Prospective, longitudinal, time-diary study using a Web-based survey. Patients or Other Participants: Fifty-three first-year, master’s-level athletic training students from 21 programs.

Main Outcome Measure(s)

Participants reported their type of clinical experience (ICE, N-ICE, or none), the …


Understanding Injury-Related Fear In Individuals With Chronic Ankle Instability: A Qualitative Approach, Ashley M. B. Suttmiller, Julie M. Cavallario, Shelby E. Baez, Ryan S. Mccann Jan 2025

Understanding Injury-Related Fear In Individuals With Chronic Ankle Instability: A Qualitative Approach, Ashley M. B. Suttmiller, Julie M. Cavallario, Shelby E. Baez, Ryan S. Mccann

Rehabilitation Sciences Faculty Publications

Context

The Tampa Scale of Kinesiophobia (TSK-11) is used to identify injury-related fear (IR-Fear) in individuals with chronic ankle instability (CAI) and is a predictor of poor health outcomes. Limited knowledge beyond quantitative scores necessitates a deeper, qualitative understanding of IR-Fear to reduce the burden of fear within CAI patients.

Objective

To explore the perceptions and experiences that influence IR-Fear within the CAI population.

Design

Consensual qualitative research.

Setting

Individual semistructured video conference interviews.

Patients or Other Participants

Nine participants with CAI were selected as a follow-up from a web-based questionnaire investigating the fear-avoidance model. Potential participants were contacted based …


Frequency And Perceived Influence Of Menopausal Symptoms On Training And Performance In Female Endurance Athletes, Heather M. Hamilton, Natalie M. Yarish, Kristin E. Heron Jan 2025

Frequency And Perceived Influence Of Menopausal Symptoms On Training And Performance In Female Endurance Athletes, Heather M. Hamilton, Natalie M. Yarish, Kristin E. Heron

Rehabilitation Sciences Faculty Publications

Menopause is associated with several negative health concerns and common menopausal symptoms. Physical activity is essential to mitigate these negative effects, but menopausal symptoms may interfere with participation in physical activity. The purpose of this study was to determine the frequency and the perceived negative effect of menopausal symptoms among female endurance athletes. Female runners, cyclists, swimmers, and triathletes 40–60 years of age were recruited (N = 187). Participants completed an online, anonymous survey that included self-reported menopausal status; the Menopausal Rating Scale (MRS), a validated measure for assessing menopausal symptoms; and the perceived effect of menopausal symptoms on …


Ai-Generated Messaging For Life Events Using Structured Prompts: A Comparative Study Of Gpt With Human Experts And Machine Learning, Christopher Lynch, Erik Jensen, Ross Gore, Virginia Zamponi, Kevin O'Brien, Brandon Feldhaus, Katherine Smith, Joseph Martínez, Madison H. Munro, Timur E. Ozkose, Tugce B. Gundogdu, Ann Marie Reinhold, Hamdi Kavak, Barry Ezell Jan 2025

Ai-Generated Messaging For Life Events Using Structured Prompts: A Comparative Study Of Gpt With Human Experts And Machine Learning, Christopher Lynch, Erik Jensen, Ross Gore, Virginia Zamponi, Kevin O'Brien, Brandon Feldhaus, Katherine Smith, Joseph Martínez, Madison H. Munro, Timur E. Ozkose, Tugce B. Gundogdu, Ann Marie Reinhold, Hamdi Kavak, Barry Ezell

VMASC Publications

Large Language Models (LLMs) play an increasingly integrated and pivotal role in generating diverse types of texts, such as social media messages, emails, narratives, and technical reports, among other textual communication forms. As AI-generated messaging filters into human communication, a systematic exploration of their effectiveness for mimicking human-like communication of life events is needed. In this study, we employ a zero-shot structured narrative prompt to generate 24,000 life event messages for birth, death, hiring, and firing events using OpenAI's GPT-4. From this dataset, we manually classify 2880 messages and evaluate their validity in conveying these life events through the form …


Examining Non-Traditional Online Learners' Ownership Of Learning In The Context Of Chatgpt-Facilitated Design, Mohan Yang, Tian Luo, Kristin Herman, Belle Li, Shanan Chappell Moots, Noah Glaser, Shiyan Jiang Jan 2025

Examining Non-Traditional Online Learners' Ownership Of Learning In The Context Of Chatgpt-Facilitated Design, Mohan Yang, Tian Luo, Kristin Herman, Belle Li, Shanan Chappell Moots, Noah Glaser, Shiyan Jiang

STEMPS Faculty Publications

Generative artificial intelligence (GenAI) offers potential solutions to educational challenges by personalizing learning experiences for diverse learners. However, it also introduces complexities around issues of ownership of learning. As an indicator of empowered learning, ownership is a multifaceted but underexplored concept. In this study, the authors adopted a mixed-methods multiple-case study design to explore non-traditional online students’ perceived ownership of learning when using ChatGPT for instructional design. The authors adopted the psychology ownership construct consisting of self-efficacy, accountability, belongingness, and self-identity as the theoretical framework. Findings revealed students’ prior AI experiences and educational levels played a significant role in their …


Socially Shared Regulation Of Learning And Artificial Intelligence: Opportunities To Support Socially Shared Regulation, Jinhee Kim, Rita Detrick, Seongryeong Yu, Yukyeong Song, Linda Bol, Na Li Jan 2025

Socially Shared Regulation Of Learning And Artificial Intelligence: Opportunities To Support Socially Shared Regulation, Jinhee Kim, Rita Detrick, Seongryeong Yu, Yukyeong Song, Linda Bol, Na Li

STEMPS Faculty Publications

Supporting learners in achieving high-level socially shared regulation of learning (SSRL) in the online collaborative learning (OCL) context presents challenges that the utilization of artificial intelligence (AI) technologies may help solve. However, the effective uses of AI to support multifaceted areas (cognition, metacognition, and motivation) and phases (forethought, performance, and reflection) of SSRL remain elusive. Furthermore, research on developing an educational AI and what pedagogical attributes and elements are required for AI to support students' SSRL effectively is limited. This study, therefore, aims to investigate students' perceptions of AI applications in enhancing SSRL and to explore the essential pedagogical elements …


Leveraging Custom Gpts For Formative Assessment And Feedback, Nari Kim, Jason Vickers, Shaimaa Alyehaibi, Chikezie Ozuzu, Xinyue Ren, Suhasini Kotcherlakota Jan 2025

Leveraging Custom Gpts For Formative Assessment And Feedback, Nari Kim, Jason Vickers, Shaimaa Alyehaibi, Chikezie Ozuzu, Xinyue Ren, Suhasini Kotcherlakota

STEMPS Faculty Publications

As artificial intelligence (AI) advances, the use of custom generative pre-trained transformers (Custom GPTs) in formative assessments opens new opportunities for improving student learning and engagement. Custom GPTs increase cognitive and emotional engagement by providing timely, context-sensitive, and tailored responses based on unique learner profiles. This paper aims to investigate how custom GPT-driven formative feedback can enhance individualized learning experiences and improve student performance. This paper will discuss the promise of this AI tool, the challenges associated with its application, and recommendations for educators and academics looking to use these technologies for formative assessments.


Bridging The Gap: The Role Of Parent-Teacher Perception In Child Developmental Outcomes, Mckayla Jensen, Mikaela J. Dufur, Jonathan A. Jarvis, Shana L. Pribesh Jan 2025

Bridging The Gap: The Role Of Parent-Teacher Perception In Child Developmental Outcomes, Mckayla Jensen, Mikaela J. Dufur, Jonathan A. Jarvis, Shana L. Pribesh

STEMPS Faculty Publications

Background/Objectives: Time spent with parents and educators encompasses a large portion of a child’s waking hours, with the home and early childhood education and care serving as two of the first settings in which children develop social and cognitive abilities. While previous studies have used social and cognitive tests to examine antecedents of child behavior, we extend such studies to take into account the congruence and incongruence of parents’ and teachers’ views on those antecedents. We examine the importance of parent-teacher alignment on the perceptions of a child’s personality and abilities in early development. Methods: Parents and teachers of 2968 …


Exploring Lis Curriculum: Agency, Identity, Practices, Holly Hebert, Amanda Harrison, Rene Burress, Kelly Pryde, Lauren Hays, Fei Yu, Elizabeth Burns, Cari Cusick Jan 2025

Exploring Lis Curriculum: Agency, Identity, Practices, Holly Hebert, Amanda Harrison, Rene Burress, Kelly Pryde, Lauren Hays, Fei Yu, Elizabeth Burns, Cari Cusick

STEMPS Faculty Publications

The practices of LIS educators provide agency and identity for developing LIS professionals. It is essential that LIS programs interrogate their curricula to best prepare emerging LIS professionals. The Curriculum SIG will present three projects that explore practices and curriculum for LIS training.

Dr. Amanda Harrison, Dr. Rene Burress, Kelly Pryde, Dr. Cari Cusick, and Dr. Lauren Hays, will present “Teaching Accessibility in a Library and Information Science MLS program.” LIS students must develop knowledge, skills, and awareness to create inclusive, accessible libraries (American Library Association, 2018; IFLA Standing Committee of Libraries Serving Disadvantaged Persons, 2005; Jaeger et …


Assessing The Impact Of Substituting Interaction Types: An Empirical Study Of The Interaction Equivalency Theory, Scott Hauert, Tian Luo, Cherng-Jyh Yen Jan 2025

Assessing The Impact Of Substituting Interaction Types: An Empirical Study Of The Interaction Equivalency Theory, Scott Hauert, Tian Luo, Cherng-Jyh Yen

STEMPS Faculty Publications

Studies on learner–learner and learner–instructor interaction provide insight into the preferences and perceived effects of interaction types. However, evidence of the impact on measured performance resulting from substituting learner–content interaction for learner–learner interaction is sparse. Using an experimental design, this study examined the impact of substituting interaction types on perception of workload, perception of learning, and measured performance in an online, asynchronous, undergraduate-level setting of formal distance education. The results of this study showed (a) learner–learner interactions were perceived to be significantly more work than learner–content interactions, (b) learner–content interactions were perceived to be significantly more helpful in learning the …


Influence Of Faculty-Derived Concept Maps On Student Study Strategies, Kaitlin P. Hardy, Amanda K. Burbage, Julie A. Kerry Jan 2025

Influence Of Faculty-Derived Concept Maps On Student Study Strategies, Kaitlin P. Hardy, Amanda K. Burbage, Julie A. Kerry

EVMS School of Health Professions Faculty Publications

Background

Concept mapping is a well-established tool for students to actively organize information into a visual and spatial framework. However, some students are resistant to adopting concept mapping as a study strategy due to the time and effort involved in generating the maps. In this study, we explored student perceptions of faculty-derived concept maps (FD-maps) developed to accompany content within a Foundational Science module in a medical school curriculum. We subsequently investigated whether student use of FD-maps helped overcome resistance to adoption of concept mapping.

Methods

Student evaluation data was analyzed using a mixed methods approach to explore student perceptions …


Anhedonia Links Sleep Problems And Suicidal Thoughts: An Intensive Longitudinal Study In High-Risk Adolescents, Kinjal K. Patel, Jaclyn C. Kearns, Dan Foti, Wilfred R. Pigeon, Evan M. Kleiman, Catherine R. Glenn Jan 2025

Anhedonia Links Sleep Problems And Suicidal Thoughts: An Intensive Longitudinal Study In High-Risk Adolescents, Kinjal K. Patel, Jaclyn C. Kearns, Dan Foti, Wilfred R. Pigeon, Evan M. Kleiman, Catherine R. Glenn

Psychology Faculty Publications

Growing research indicates that sleep problems are a robust independent risk factor for suicidal thoughts and behaviors among youth. However, relatively little is known about how this risk is conferred. This study used an intensive longitudinal design to investigate anhedonia as a mechanism linking sleep problems and next-day suicidal thoughts in a clinically high-risk sample of adolescents. Adolescents (N = 48; Mage=14.96; 77.1% white, 64.6% female) completed an ecological momentary assessment (EMA) study design for 28 days following discharge from acute psychiatric care for suicide risk. Daily sleep diaries were used to assess prior night total sleep …


Brief Videos During Informed Consent May Be Helpful For Participants' Understanding Of Study Information, Abby L. Braitman, Rachel Ayala Guzman, Kristin E. Heron Jan 2025

Brief Videos During Informed Consent May Be Helpful For Participants' Understanding Of Study Information, Abby L. Braitman, Rachel Ayala Guzman, Kristin E. Heron

Psychology Faculty Publications

Although an informed consent process is required for all research, it is not clear how well study participants read informed consent forms and understand their content. A systematic review of medical clinical trials revealed participants had only a 50% rate of understanding for concepts of the consent process, including voluntary participation, blinding, and freedom to withdraw, with lower rates for randomization, risks, and safety issues (Pietrzykowski & Smilowska, 2021). This issue may be more pronounced for online research, with a recent study indicating half of participants report not reading informed consent forms at all (Perrault & Keating, 2017). Although increasing …


Identifying Salient Social, Environmental, And Situational Contexts Of College Drinking: Impacts Across Drinking Outcomes, Abby L. Braitman, Jennifer L. Shipley, Megan Strowger, Emily S. Renzoni Jan 2025

Identifying Salient Social, Environmental, And Situational Contexts Of College Drinking: Impacts Across Drinking Outcomes, Abby L. Braitman, Jennifer L. Shipley, Megan Strowger, Emily S. Renzoni

Psychology Faculty Publications

Background and Objectives: Drinking context, such as where, why, and under what social conditions drinking occurs, is consistently associated with daily variability in alcohol use. However, ecological momentary assessment (EMA) requires very brief measurement, not allowing for as many contextual assessments as researchers may like. The current investigation examined common contextual predictors and their associations with different alcohol outcomes.

Methods: A sample of N=528 college drinkers completed three surveys about their most recent drinking episode. This included contextual predictors (location, social context, who was present, alcohol offers, and drinking motives), as well as typical drinking outcomes (number of drinks, estimated …


Automation To Autonomy: Temporal Dynamics Of Trust And Visual Attention Allocation Did Not Evolve, Tetsuya Sato, Eric Chancey, Yusuke Yamani Jan 2025

Automation To Autonomy: Temporal Dynamics Of Trust And Visual Attention Allocation Did Not Evolve, Tetsuya Sato, Eric Chancey, Yusuke Yamani

Psychology Faculty Publications

Emerging work environments are expected to implement autonomy that performs various functions without human input. Previous works has shown that trust in automation is negatively correlated with visual attention allocation, indicating that trust is a dynamic construct. Moreover, trust in automation and trust in autonomy appears to evolve in similar ways. However, recent work has demonstrated differences between trust in automation and trust in autonomy within Kaber’s (2018) theoretical framework (Sato et al., 2023b). Yet, it is uncertain whether the development of trust and visual attention allocation differs between automation and autonomy. The present study examined the temporal dynamics of …


Cellphone Separation Modulates The Effects Of Working Memory Load On Ex-Gaussian Parameters Of Choice Reaction Time, Michael Gazzanigo, Alexa Quesnel, Catalina Roldan, Xiao Yang Jan 2025

Cellphone Separation Modulates The Effects Of Working Memory Load On Ex-Gaussian Parameters Of Choice Reaction Time, Michael Gazzanigo, Alexa Quesnel, Catalina Roldan, Xiao Yang

Psychology Faculty Publications

Cognitive effects of cellphone dependency among young adults have garnered increasing research attention. While cellphones have been identified as a distractor in daily tasks, related psychological processes remain unclear. As a potential mechanism underlying those effects of cellphones, excessive working memory (WM) load has not yet been well examined. Our study investigated the effects of the mental representation of cellphone separation on WM. Seventy-five participants (M(age) = 21.3 years; 55 females, 20 males) were assigned into three groups: the cued separation, natural separation, or control group, and completed a block of choice reaction time (CRT) task, and a dual-task block: …


Exploring Institutional Stratification: Minority-Serving Institutional Pathways To Medical School Acceptance In The United States, Amanda K. Burbage, Eushekia Y. Hewitt Jan 2025

Exploring Institutional Stratification: Minority-Serving Institutional Pathways To Medical School Acceptance In The United States, Amanda K. Burbage, Eushekia Y. Hewitt

EVMS School of Health Professions Faculty Publications

Introduction

Recruiting and training a diverse pool of physicians from historically excluded groups is vital to solving complex scientific problems and increasing access to patient care. Disparate educational and health outcomes of COVID-19 amplified this need. In stratified higher education systems, underfunded institutions that serve greater numbers of underrepresented in medicine (URM) students face unique barriers to entering physician training. However, pathways from historically underfunded minority-serving institutions (MSIs) in the United States to medical school (MD) are not well understood.

Method

A hierarchical logistic regression analysis of 328 488 de-identified applicants to US MD-granting medical schools for academic years 2017-2018 …


Reduced Set-Shifting Processing Speed In Male Rats Following Low Dose (10 Cgy) Proton Exposure, Hui Ho Vanessa Chang, Gyutae Kim, Kyu-Sung Kim, Richard A. Britten Jan 2025

Reduced Set-Shifting Processing Speed In Male Rats Following Low Dose (10 Cgy) Proton Exposure, Hui Ho Vanessa Chang, Gyutae Kim, Kyu-Sung Kim, Richard A. Britten

Center for Integrative Neuroscience and Inflammatory Diseases (CINID) Faculty Publications

Space radiation (SR) exposure poses significant biomedical risks, including effects on the central nervous system (CNS). These risks are particularly relevant to cognitive function during long-duration space missions. One critical cognitive skill is decision-making, which requires attentional set-shifting (ATSET)—the ability to quickly assess problems, evaluate options, and select the best actions. Previous studies have shown that exposure to However, the impact of low LET (< 1 keV/μm) protons, which significantly contribute to the total radiation flux astronauts encounter within spacecraft, on ATSET performance is unknown. To address this gap, we evaluated the effects of cranial irradiation with 10 cGy of 100 MeV/n protons (LET = 0.732 keV/μm) on ATSET performance in male Sprague-Dawley rats. We also investigated whether concurrent exposure to variable gravity (hypergravity step-up, step down, purported to have the same effect as exposure to microgravity (another major spaceflight stressor) exacerbated SR-induced cognitive deficits. Our findings indicate that proton exposure alone significantly impaired ATSET performance, as evidenced by decreased processing speed while performing compound discrimination reversal and extra-dimensional shifting. Notably, no additive or synergistic effects were observed when hypergravity was combined with proton exposure. The impact that low-dose proton exposure has on CNS functionality, particularly in reducing processing speed during complex tasks, warrant further investigation. If similar cognitive deficits were to occur in astronauts exposed to galactic cosmic rays, mission success and safety could be significantly compromised.


Neuroinflammatory Signaling And Immune Cell Infiltration Differ In Brains Of Rats Exposed To Space Radiation And Social Isolation, Austin M. Adkins, Zachary N. M. Luyo, Alea F. Boden, Riley S. Heerbrandt, Richard A. Britten, Laurie L. Wellman, Larry D. Sanford Jan 2025

Neuroinflammatory Signaling And Immune Cell Infiltration Differ In Brains Of Rats Exposed To Space Radiation And Social Isolation, Austin M. Adkins, Zachary N. M. Luyo, Alea F. Boden, Riley S. Heerbrandt, Richard A. Britten, Laurie L. Wellman, Larry D. Sanford

Center for Integrative Neuroscience and Inflammatory Diseases (CINID) Faculty Publications

Astronauts on the proposed Mars missions will be exposed to extended periods of social isolation (SI) and space radiation (SR). SI and SR-induced immune dysregulation can result in persistent neuroinflammation and neuronal damage which could negatively impact an astronaut’s health and ability to maintain adequate levels of performance. The synergistic effects of combined SI and SR on immune system functionality and the brain remain unknown. Determining how single and combined inflight stressors modulate the immune system is crucial for fully understanding pathways impacting astronaut health and performance. We used ground-based analogs of SI and SR in rodent models to investigate …


Mobile Health Intervention Tools Promoting Hiv Pre-Exposure Prophylaxis Among Adolescent Girls And Young Women In Sub-Saharan Africa: Scoping Review, Alex Emilio Fischer, Homaira Hanif, Jacob B. Stocks, Aimee E. Rochelle, Karen Dominguez, Eliana Gabriela Armora Langoni, H. Luz Mcnaughton Reyes, Gustavo F. Doncel, Kathryn E. Muessig Jan 2025

Mobile Health Intervention Tools Promoting Hiv Pre-Exposure Prophylaxis Among Adolescent Girls And Young Women In Sub-Saharan Africa: Scoping Review, Alex Emilio Fischer, Homaira Hanif, Jacob B. Stocks, Aimee E. Rochelle, Karen Dominguez, Eliana Gabriela Armora Langoni, H. Luz Mcnaughton Reyes, Gustavo F. Doncel, Kathryn E. Muessig

Department of Obstetrics & Gynecology Faculty Publications

Background:

In 2022, 3100 adolescent girls and young women in sub-Saharan Africa experienced new HIV infections each week. HIV pre-exposure prophylaxis (PrEP) is effective at preventing HIV but has limited uptake and persistence. Mobile health (mHealth) interventions can improve medication adherence; however, their utility to improve PrEP adherence among adolescent girls and young women is not well established.

Objective:

This scoping review synthesizes evidence supporting mHealth for PrEP among adolescent girls and young women in sub-Saharan Africa and identifies strategies for further evaluation.

Methods:

We searched PubMed and Google Scholar databases, expert referrals, and reference lists using the following eligibility …


Racial Disparities In Maternal Mortality Before, During, And After The Covid-19 Pandemic In The United States: A Difference-In-Difference Analysis, Kyosuke Kamijo, Misa Hayasaka, Tetsuya Kawakita Jan 2025

Racial Disparities In Maternal Mortality Before, During, And After The Covid-19 Pandemic In The United States: A Difference-In-Difference Analysis, Kyosuke Kamijo, Misa Hayasaka, Tetsuya Kawakita

Department of Obstetrics & Gynecology Faculty Publications

Background

This study aimed to examine changes in racial disparities in pregnancy-related and maternal mortality before, during, and after the COVID-19 pandemic in the United States.

Methodology

This was a cross-sectional study using the Centers for Disease Control and Prevention Wide-ranging Online Data for Epidemiologic Research (CDC WONDER) data from January 2018 to June 2024. We focused on pregnancy-related and maternal mortality among Black and White individuals to examine racial disparities. The study periods were defined as pre-pandemic (January 2018-March 2020), pandemic (April 2020-March 2022), and post-pandemic (April 2022-June 2024). We applied interrupted time series analysis and difference-in-difference (DID) models …


Treatment Effects Of Genital Mycoplasma Species In High-Risk Pregnant Individuals: A Retrospective Cohort Study, Takashi Yoshimasu, Tasuku Inao, Tetsuya Kawakita Jan 2025

Treatment Effects Of Genital Mycoplasma Species In High-Risk Pregnant Individuals: A Retrospective Cohort Study, Takashi Yoshimasu, Tasuku Inao, Tetsuya Kawakita

Department of Obstetrics & Gynecology Faculty Publications

Objective

We aimed to estimate the causal effect of treatment for genital Mycoplasma species on preterm birth (PTB) and spontaneous abortion (SA). We also evaluated treatment effects separately for cases with co-infection of Ureaplasma and Mycoplasma species.

Methods

This was a retrospective observational cohort study at a single center. Singleton mothers with one or more risk factors for PTBs were screened and treated for genital Mycoplasma species. The treatment was repeated based on polymerase chain reaction (PCR) results after each course. We applied inverse probability treatment weighting, and risk differences (RDs) of the treatment effect on pregnancy outcomes were estimated …


Psychedelic Minimalism: The Case Against Music In Psychedelic Therapy Settings, Samir A. Nader Jan 2025

Psychedelic Minimalism: The Case Against Music In Psychedelic Therapy Settings, Samir A. Nader

Department of Medicine Faculty Publications

[Introduction: reframing the role of setting] In recent years, renewed attention has been given to the centrality of set and setting in psychedelic-assisted therapy. The Reporting of Setting in Psychedelic Clinical Trials (ReSPCT) guidelines reflect an evolving consensus: therapeutic outcomes are not solely pharmacologically determined but are heavily shaped by both the environment and the psychological state of the participant (2). Within this evolving paradigm, music has assumed a privileged role, framed as a therapeutic constant, typically curated to be emotionally supportive or evocative, and especially emphasized during peak psychedelic states (3). The prevailing assumption is that music facilitates safety, …


A Case Study Using The Transparency Framework And Artificial Intelligence To Promote Effective Writing And Student Success In A Writing-Intensive Course, Elizabeth A. Brown, Maria Kronenburg, Ashlee Steeley, Diana Tagbor Jan 2025

A Case Study Using The Transparency Framework And Artificial Intelligence To Promote Effective Writing And Student Success In A Writing-Intensive Course, Elizabeth A. Brown, Maria Kronenburg, Ashlee Steeley, Diana Tagbor

Health Behavior, Policy & Management Faculty Publications

Program evaluation data suggest that undergraduate students struggle with writing in a clear and concise manner and appropriately citing. Faculty implemented the plan-do study-act cycle to pilot the Transparency in Learning and Teaching (TILT) project framework and to explore the use of artificial intelligence (AI) and discuss approaches to using AI, along with the TILT framework, in a writing-intensive course to identify the pros and cons of using ChatGPT in an online classroom. The TILT framework reinforces adult learning by helping students clearly understand the assignment's purpose and establish a clear relationship between assignment and students' professional lives. Faculty encouraged …